3	S000002143	ORF	Dubious	YAL069W	n.a.	1	335	649	W	Hypothetical protein
6	S000028594	ORF	Dubious	YAL068W-A	n.a.	1	538	792	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11	S000002142	ORF	Uncharacterized	YAL068C	n.a.	1	2169	1807	C	Hypothetical protein
13	S000028593	ORF	Uncharacterized	YAL067W-A	n.a.	1	2480	2707	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15	S000000062	ORF	Verified	YAL067C	SEO1	1	9017	7236	C	Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide
17	S000000061	ORF	Dubious	YAL066W	n.a.	1	10092	10400	W	Hypothetical protein
19	S000001817	ORF	Uncharacterized	YAL065C	n.a.	1	11952	11566	C	Hypothetical protein
21	S000002141	ORF	Uncharacterized	YAL064W-B	n.a.	1	12047	12427	W	Hypothetical protein
23	S000002140	ORF	Uncharacterized	YAL064C-A	n.a.	1	13744	13364	C	Hypothetical protein
25	S000000060	ORF	Uncharacterized	YAL064W	n.a.	1	21526	21852	W	Hypothetical protein
28	S000028813	ORF	Uncharacterized	YAL063C-A	n.a.	1	22687	22397	C	Identified by expression profiling and mass spectrometry
30	S000000059	ORF	Verified	YAL063C	FLO9	1	27969	24001	C	Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation
32	S000000058	ORF	Verified	YAL062W	GDH3	1	31568	32941	W	NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources
34	S000000057	ORF	Uncharacterized	YAL061W	n.a.	1	33449	34702	W	putative polyol dehydrogenase
36	S000000056	ORF	Verified	YAL060W	BDH1	1	35156	36304	W	NAD-dependent (2R,3R)-2,3-butanediol dehydrogenase, a zinc-containing medium-chain alcohol dehydrogenase, produces 2,3-butanediol from acetoin during fermentation and allows using 2,3-butanediol as a carbon source during aerobic growth
38	S000000055	ORF	Verified	YAL059W	ECM1	1	36510	37148	W	Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export
40	S000028734	ORF	Dubious	YAL059C-A	n.a.	1	36919	36497	C	Questionable ORF from MIPS
42	S000000054	ORF	Verified	YAL058W	CNE1	1	37465	38973	W	Calnexin; integral membrane ER chaperone involved in the folding and quality control of glycoproteins, 24% identical and 31% similar to mammalian calnexin but the Ca+ binding typical of calnexins has not been demonstrated in yeast
44	S000002139	ORF	Dubious	YAL056C-A	n.a.	1	39047	38697	C	Hypothetical protein
46	S000000052	ORF	Verified	YAL056W	GPB2	1	39260	41902	W	Proposed beta subunit of the heterotrimeric G protein that interacts with the receptor Grp1p, has signaling role in response to nutrients; involved in regulation of pseudohyphal growth through cAMP levels; homolog of Gpb1p
48	S000000051	ORF	Verified	YAL055W	PEX22	1	42178	42720	W	Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation
50	S000000050	ORF	Verified	YAL054C	ACS1	1	45023	42882	C	Acetyl-coA synthetase isoform, expressed during growth on nonfermentable carbon sources and under aerobic conditions
52	S000000049	ORF	Uncharacterized	YAL053W	n.a.	1	45900	48251	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
54	S000000048	ORF	Verified	YAL051W	OAF1	1	48565	51708	W	Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis
56	S000000047	ORF	Uncharacterized	YAL049C	n.a.	1	52596	51856	C	Hypothetical protein
58	S000028733	ORF	Dubious	YAL047W-A	n.a.	1	54585	54914	W	Hypothetical protein
60	S000000046	ORF	Uncharacterized	YAL048C	GEM1	1	54790	52802	C	Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochondrial morphology; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; not required for pheromone-induced cell death
62	S000000045	ORF	Verified	YAL047C	SPC72	1	56858	54990	C	Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them to microtubules; has roles in astral microtubule formation and stabilization
64	S000000044	ORF	Uncharacterized	YAL046C	n.a.	1	57386	57030	C	Hypothetical protein
66	S000007586	ORF	Uncharacterized	YAL044W-A	n.a.	1	57519	57851	W	Similar to pombe uvi31, putative DNA repair protein
68	S000000043	ORF	Dubious	YAL045C	n.a.	1	57797	57489	C	Hypothetical protein
70	S000000042	ORF	Verified	YAL044C	GCV3	1	58463	57951	C	H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm
72	S000000041	ORF	Verified	YAL043C	PTA1	1	61053	58696	C	Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII
74	S000000040	ORF	Verified	YAL042W	ERV46	1	61317	62564	W	Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport
76	S000002138	ORF	Dubious	YAL042C-A	n.a.	1	61609	61232	C	Hypothetical protein
78	S000000039	ORF	Verified	YAL041W	CDC24	1	62841	65405	W	Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing
80	S000000038	ORF	Verified	YAL040C	CLN3	1	67521	65779	C	G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis
82	S000000037	ORF	Verified	YAL039C	CYC3	1	69526	68717	C	Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-Cyc1p in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)
84	S000000036	ORF	Verified	YAL038W	CDC19	1	71787	73289	W	Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration
86	S000028592	ORF	Dubious	YAL037C-B	n.a.	1	73301	72327	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
88	S000028732	ORF	Uncharacterized	YAL037C-A	n.a.	1	73519	73427	C	Identified by SAGE
90	S000000035	ORF	Uncharacterized	YAL037W	n.a.	1	74021	74824	W	Hypothetical protein
92	S000000034	ORF	Verified	YAL036C	RBG1	1	76153	75044	C	Member of the DRG family of GTP-binding proteins; interacts with translating ribosomes
94	S000000033	ORF	Verified	YAL035W	FUN12	1	76428	79436	W	GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2
96	S000000032	ORF	Verified	YAL034W-A	MTW1	1	79719	80588	W	Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly
98	S000002137	ORF	Dubious	YAL034C-B	n.a.	1	79843	79490	C	Protein required for cell viability
100	S000002134	ORF	Verified	YAL034C	FUN19	1	81952	80711	C	Non-essential protein of unknown function
102	S000000031	ORF	Verified	YAL033W	POP5	1	82707	83228	W	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
104	S000000030	ORF	Verified	YAL032C	PRP45	1	84475	83336	C	Ortholog of human transcriptional coactivator SKIP, can activate transcription of a reporter gene; interacts with splicing factors Prp22p and Prp46p
106	S000028731	ORF	Dubious	YAL031W-A	n.a.	1	84670	84978	W	Questionable ORF from MIPS
108	S000000029	ORF	Verified	YAL031C	n.a.	1	87032	84750	C	Cytoplasmic Glc7p-interacting protein, potential Cdc28p substrate
110	S000000028	ORF	Verified	YAL030W	SNC1	1	87287	87753	W	Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins
113	S000033439	intron	n.a.	n.a.	n.a.	1	87389	87501	W	n.a.
114	S000000027	ORF	Verified	YAL029C	MYO4	1	92271	87856	C	One of two type V myosins; required for mother-specific HO expression, for the bud tip localization of ASH1 and IST2 mRNA; facilitates growth and orientation of ER tubules along with She3p
116	S000000026	ORF	Verified	YAL028W	FRT2	1	92901	94487	W	Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate
118	S000000025	ORF	Uncharacterized	YAL027W	n.a.	1	94688	95473	W	Hypothetical protein
120	S000028730	ORF	Dubious	YAL026C-A	n.a.	1	95824	95387	C	Questionable ORF from MIPS
122	S000000024	ORF	Verified	YAL026C	DRS2	1	99698	95631	C	Integral membrane Ca(2+)-ATPase, potential aminophospholipid translocase required to form a specific class of secretory vesicles that accumulate upon actin cytoskeleton disruption; mutation affects maturation of the 18S rRNA
124	S000000023	ORF	Verified	YAL025C	MAK16	1	101146	100226	C	Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for normal concentration of free 60S ribosomal subunits; required for maintenance of M1 satellite double-stranded RNA of the L-A virus
126	S000000022	ORF	Verified	YAL024C	LTE1	1	105873	101566	C	Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP
128	S000000021	ORF	Verified	YAL023C	PMT2	1	108552	106273	C	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals
130	S000000020	ORF	Verified	YAL022C	FUN26	1	110431	108878	C	Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes
132	S000000019	ORF	Verified	YAL021C	CCR4	1	113360	110847	C	Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening
134	S000028729	ORF	Dubious	YAL019W-A	n.a.	1	114251	114820	W	Questionable ORF from MIPS
136	S000000018	ORF	Verified	YAL020C	ATS1	1	114616	113615	C	Protein with a potential role in regulatory interactions between microtubules and the cell cycle, as suggested by genetic and physical interactions with Nap1p and genetic interactions with TUB1
138	S000000017	ORF	Verified	YAL019W	FUN30	1	114920	118315	W	Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p
140	S000000016	ORF	Uncharacterized	YAL018C	n.a.	1	119542	118565	C	Hypothetical protein
142	S000000015	ORF	Verified	YAL017W	PSK1	1	120226	124296	W	One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status
144	S000028528	ORF	Uncharacterized	YAL016C-B	n.a.	1	124493	124308	C	Identified by fungal homology and RT-PCR
146	S000000014	ORF	Verified	YAL016W	TPD3	1	124880	126787	W	Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III
148	S000028728	ORF	Dubious	YAL016C-A	n.a.	1	125070	124756	C	Questionable ORF from MIPS
150	S000000013	ORF	Verified	YAL015C	NTG1	1	128103	126904	C	DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus and mitochondrion
152	S000000012	ORF	Verified	YAL014C	SYN8	1	129020	128253	C	Endosomal SNARE related to mammalian syntaxin 8
154	S000000011	ORF	Verified	YAL013W	DEP1	1	129271	130533	W	Transcriptional modulator involved in the regulation of structural genes involved in phospholipid biosynthesis, also participates in regulation of metabolically unrelated genes as well as maintenance of mating efficiency and sporulation
156	S000000010	ORF	Verified	YAL012W	CYS3	1	130802	131986	W	Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine;
158	S000000009	ORF	Verified	YAL011W	SWC3	1	132202	134079	W	Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae
160	S000000008	ORF	Verified	YAL010C	MDM10	1	135667	134186	C	Subunit of the mitochondrial sorting and assembly machinery (SAM complex); has a role in assembly of the TOM complex, which mediates protein import through the outer membrane; required for normal mitochondrial morphology and inheritance
162	S000000007	ORF	Verified	YAL009W	SPO7	1	135856	136635	W	Integral nuclear/ER membrane protein of unknown function, required for normal nuclear envelope morphology and sporulation
164	S000000006	ORF	Verified	YAL008W	FUN14	1	136916	137512	W	Mitochondrial protein of unknown function
166	S000000005	ORF	Verified	YAL007C	ERP2	1	138347	137700	C	Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
169	S000006680	tRNA	n.a.	tP(UGG)A	TRN1	1	139154	139256	W	tRNA-Pro
170	S000035969	intron	n.a.	n.a.	n.a.	1	139190	139220	W	n.a.
173	S000002136	ORF	Dubious	YAL004W	n.a.	1	140762	141409	W	Hypothetical protein
175	S000000004	ORF	Verified	YAL005C	SSA1	1	141433	139505	C	ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall
177	S000000003	ORF	Verified	YAL003W	EFB1	1	142176	143162	W	Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site
180	S000031943	intron	n.a.	n.a.	n.a.	1	142256	142621	W	n.a.
181	S000007500	snoRNA	n.a.	snR18	SNR18	1	142374	142475	W	guides 2'-O-methylation on large subunit rRNA at A649 and A650; U18 snoRNA
183	S000000002	ORF	Verified	YAL002W	VPS8	1	143709	147533	W	involved in vacuolar protein sorting; required for localization and trafficking of the CPY sorting receptor; Vps8p is a membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the RING finger Zn2+ binding motif.
185	S000000001	ORF	Verified	YAL001C	TFC3	1	151168	147596	C	Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding
188	S000030736	intron	n.a.	n.a.	n.a.	1	151098	151009	C	n.a.
193	S000000063	ORF	Verified	YAR002W	NUP60	1	152259	153878	W	Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a dynamic process that is controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate
195	S000002129	ORF	Verified	YAR002C-A	ERP1	1	154726	154067	C	Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles
197	S000000064	ORF	Verified	YAR003W	SWD1	1	155007	156287	W	Subunit of the COMPASS (Set1C) complex, which methylates Rad6p ubiquitinated histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7
199	S000000065	ORF	Verified	YAR007C	RFA1	1	158621	156756	C	Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
201	S000000066	ORF	Verified	YAR008W	SEN34	1	158967	159794	W	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease
212	S000006521	tRNA	n.a.	tA(UGC)A	n.a.	1	166268	166340	W	tRNA-Ala
214	S000000069	ORF	Verified	YAR014C	BUD14	1	168866	166743	C	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
216	S000000070	ORF	Verified	YAR015W	ADE1	1	169370	170290	W	N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine
218	S000000071	ORF	Verified	YAR018C	KIN3	1	171698	170391	C	Nonessential protein kinase with unknown cellular role
220	S000028735	ORF	Dubious	YAR019W-A	n.a.	1	174996	175340	W	Questionable ORF from MIPS
222	S000000072	ORF	Verified	YAR019C	CDC15	1	175133	172209	C	Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p
224	S000000073	ORF	Verified	YAR020C	PAU7	1	177021	176854	C	Part of 23-member seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme
226	S000000074	ORF	Uncharacterized	YAR023C	n.a.	1	179818	179279	C	Putative integral membrane protein, member of DUP240 gene family
228	S000006636	tRNA	n.a.	tL(CAA)A	SUP56	1	181135	181248	W	tRNA-Leu
229	S000033745	intron	n.a.	n.a.	n.a.	1	181173	181204	W	n.a.
232	S000006719	tRNA	n.a.	tS(AGA)A	n.a.	1	182597	182516	C	tRNA-Ser
236	S000000075	ORF	Verified	YAR027W	UIP3	1	183764	184471	W	Putative integral membrane protein of unknown function; interacts with Ulp1p at the nuclear periphery; member of DUP240 gene family
238	S000000076	ORF	Uncharacterized	YAR028W	n.a.	1	184886	185590	W	Putative integral membrane protein, member of DUP240 gene family
240	S000000077	ORF	Uncharacterized	YAR029W	n.a.	1	186315	186539	W	Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
242	S000000078	ORF	Verified	YAR031W	PRM9	1	186830	187726	W	Pheromone-regulated protein with 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding
244	S000001821	ORF	Dubious	YAR030C	n.a.	1	186847	186506	C	Hypothetical protein
246	S000000079	ORF	Verified	YAR033W	MST28	1	188101	188805	W	Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles
249	S000000080	ORF	Verified	YAR035W	YAT1	1	190187	192250	W	Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix
251	S000028595	ORF	Uncharacterized	YAR035C-A	n.a.	1	192411	192331	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
253	S000000081	ORF	Verified	YAR042W	SWH1	1	192613	196179	W	Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction
255	S000000083	ORF	Dubious	YAR047C	n.a.	1	201780	201460	C	Hypothetical protein
257	S000000084	ORF	Verified	YAR050W	FLO1	1	203394	208007	W	Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p
259	S000000085	ORF	Dubious	YAR053W	n.a.	1	208358	208654	W	Hypothetical protein
262	S000000086	ORF	Dubious	YAR060C	n.a.	1	217483	217148	C	Hypothetical protein
268	S000000089	ORF	Uncharacterized	YAR064W	n.a.	1	220189	220488	W	Hypothetical protein
270	S000002144	ORF	Uncharacterized	YAR066W	n.a.	1	221040	221651	W	Hypothetical protein
272	S000000091	ORF	Uncharacterized	YAR068W	n.a.	1	222397	222882	W	putative membrane protein
274	S000000092	ORF	Dubious	YAR069C	n.a.	1	224295	224002	C	Hypothetical protein
276	S000000093	ORF	Dubious	YAR070C	n.a.	1	224853	224554	C	Hypothetical protein
278	S000000094	ORF	Verified	YAR071W	PHO11	1	225451	226854	W	One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2
280	S000000095	ORF	Verified	YAR073W	IMD1	1	227733	228944	W	Nonfunctional protein with homology to IMP dehydrogenase; IMD1 is a probable pseudogene that is located close to the telomere and is not expressed at detectable levels
282	S000002145	ORF	Uncharacterized	YAR075W	n.a.	1	228835	229308	W	Hypothetical protein
292	S000028665	ORF	Dubious	YJL225W-A	n.a.	10	829	1311	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
294	S000003760	ORF	Uncharacterized	YJL225C	n.a.	10	6130	466	C	Hypothetical protein
297	S000033323	intron	n.a.	n.a.	n.a.	10	4969	4582	C	n.a.
307	S000003759	ORF	Verified	YJL223C	PAU1	10	9138	8776	C	Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
309	S000028664	ORF	Dubious	YJL222W-B	n.a.	10	9346	9483	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
311	S000028663	ORF	Dubious	YJL222W-A	n.a.	10	9452	9679	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
313	S000003758	ORF	Verified	YJL222W	VTH2	10	11475	16124	W	Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting
316	S000003756	ORF	Dubious	YJL220W	n.a.	10	18243	18695	W	Hypothetical protein
318	S000003757	ORF	Verified	YJL221C	FSP2	10	18536	16767	C	Protein of unknown function, expression is induced during nitrogen limitation
320	S000003755	ORF	Verified	YJL219W	HXT9	10	19497	21200	W	Putative hexose transporter that is nearly identical to Hxt11p, has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p
322	S000003754	ORF	Uncharacterized	YJL218W	n.a.	10	21973	22563	W	Hypothetical protein
324	S000003753	ORF	Uncharacterized	YJL217W	n.a.	10	23133	23729	W	Hypothetical protein
327	S000003752	ORF	Uncharacterized	YJL216C	n.a.	10	26086	24341	C	Protein of unknown function, transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
329	S000003751	ORF	Dubious	YJL215C	n.a.	10	26771	26412	C	Hypothetical protein
331	S000003750	ORF	Verified	YJL214W	HXT8	10	26887	28596	W	Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
333	S000003749	ORF	Uncharacterized	YJL213W	n.a.	10	32163	33158	W	Hypothetical protein
335	S000003748	ORF	Verified	YJL212C	OPT1	10	36249	33850	C	Plasma membrane transporter that transports tetra- and pentapeptides and glutathione; member of the OPT family
337	S000003746	ORF	Verified	YJL210W	PEX2	10	36919	37734	W	RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms putative translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import
339	S000003747	ORF	Dubious	YJL211C	n.a.	10	37200	36757	C	Hypothetical protein
341	S000003745	ORF	Verified	YJL209W	CBP1	10	38005	39969	W	Protein required for COB mRNA stability or 5' processing, required for translation of COB mRNAs
343	S000003744	ORF	Verified	YJL208C	NUC1	10	41183	40194	C	Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination
345	S000003743	ORF	Uncharacterized	YJL207C	n.a.	10	47433	41389	C	Hypothetical protein
347	S000003741	ORF	Uncharacterized	YJL206C	n.a.	10	49935	47659	C	Hypothetical protein
349	S000003742	ORF	Verified	YJL205C	NCE101	10	50443	50139	C	Protein of unknown function, involved in secretion of proteins that lack classical secretory signal sequences
352	S000034431	intron	n.a.	n.a.	n.a.	10	50411	50269	C	n.a.
353	S000003740	ORF	Verified	YJL204C	RCY1	10	53151	50629	C	F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth
355	S000003739	ORF	Verified	YJL203W	PRP21	10	53341	54183	W	Subunit of the SF3a splicing factor complex, required for spliceosome assembly
357	S000003738	ORF	Dubious	YJL202C	n.a.	10	54290	53943	C	Protein required for cell viability
359	S000003737	ORF	Verified	YJL201W	ECM25	10	54379	56178	W	Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p
361	S000003736	ORF	Uncharacterized	YJL200C	n.a.	10	58813	56444	C	Hypothetical protein
363	S000006743	tRNA	n.a.	tT(AGU)J	n.a.	10	59172	59100	C	tRNA-Thr
366	S000003735	ORF	Dubious	YJL199C	MBB1	10	60181	59855	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; protein detected in large-scale protein-protein interaction studies
368	S000003734	ORF	Verified	YJL198W	PHO90	10	60843	63488	W	Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
370	S000003733	ORF	Verified	YJL197W	UBP12	10	63804	67568	W	Ubiquitin-specific protease present in the nucleus and cytoplasm that cleaves ubiquitin from ubiquitinated proteins
372	S000028839	ORF	Dubious	YJL197C-A	n.a.	10	66085	65804	C	Identified by expression profiling and mass spectrometry
375	S000003732	ORF	Verified	YJL196C	ELO1	10	68781	67849	C	Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids
377	S000003730	ORF	Verified	YJL194W	CDC6	10	69337	70878	W	Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p
379	S000003731	ORF	Dubious	YJL195C	n.a.	10	69941	69240	C	Protein required for cell viability
381	S000003729	ORF	Uncharacterized	YJL193W	n.a.	10	71365	72573	W	Hypothetical protein
383	S000003728	ORF	Verified	YJL192C	SOP4	10	73413	72709	C	suppressor of pma1-7
385	S000003727	ORF	Verified	YJL191W	RPS14B	10	73786	74610	W	Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins
388	S000032006	intron	n.a.	n.a.	n.a.	10	73796	74203	W	n.a.
389	S000003726	ORF	Verified	YJL190C	RPS22A	10	75301	74909	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins
391	S000003725	ORF	Verified	YJL189W	RPL39	10	75932	76473	W	Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; exhibits genetic interactions with SIS1 and PAB1
394	S000030846	intron	n.a.	n.a.	n.a.	10	75938	76323	W	n.a.
395	S000003724	ORF	Dubious	YJL188C	BUD19	10	76509	76201	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 88% of ORF overlaps the verified gene RPL39; diploid mutant displays a weak budding pattern phenotype in a systematic assay
397	S000003723	ORF	Verified	YJL187C	SWE1	10	79261	76802	C	Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate
399	S000003722	ORF	Verified	YJL186W	MNN5	10	80153	81913	W	Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
401	S000003721	ORF	Uncharacterized	YJL185C	n.a.	10	82974	82093	C	Hypothetical protein
403	S000003720	ORF	Verified	YJL184W	GON7	10	83446	83817	W	Protein of unknown function, proposed to be involved in the transfer of mannosylphosphate groups onto N-linked oligosaccharides; also proposed to be involved in responding to osmotic stress
405	S000003719	ORF	Verified	YJL183W	MNN11	10	84066	85334	W	Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p
407	S000003717	ORF	Uncharacterized	YJL181W	n.a.	10	85658	87493	W	Hypothetical protein
409	S000003718	ORF	Dubious	YJL182C	n.a.	10	85750	85433	C	Hypothetical protein
411	S000003716	ORF	Verified	YJL180C	ATP12	10	88558	87581	C	Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase
413	S000003715	ORF	Verified	YJL179W	PFD1	10	88785	89114	W	Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin
415	S000003714	ORF	Verified	YJL178C	ATG27	10	90095	89280	C	Type II membrane protein that binds phosphatidylinositol 3-phosphate, required for the cytoplasm-to-vacuole targeting (Cvt) pathway
417	S000003713	ORF	Verified	YJL177W	RPL17B	10	90784	91655	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins
420	S000033685	intron	n.a.	n.a.	n.a.	10	91093	91409	W	n.a.
421	S000003711	ORF	Dubious	YJL175W	n.a.	10	94047	94559	W	Hypothetical protein
423	S000003712	ORF	Verified	YJL176C	SWI3	10	94528	92051	C	One of 11 subunits of the SWI/SNF chromatin remodeling complex that regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2
425	S000003710	ORF	Verified	YJL174W	KRE9	10	95090	95920	W	Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects
427	S000003709	ORF	Verified	YJL173C	RFA3	10	96527	96159	C	Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
429	S000003708	ORF	Verified	YJL172W	CPS1	10	97731	99461	W	Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions
432	S000003707	ORF	Uncharacterized	YJL171C	n.a.	10	100888	99698	C	Hypothetical protein
434	S000003706	ORF	Verified	YJL170C	ASG7	10	101695	101144	C	Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell; specific to a-cells and induced by alpha-factor
436	S000003705	ORF	Dubious	YJL169W	n.a.	10	102092	102460	W	Hypothetical protein
438	S000003704	ORF	Verified	YJL168C	SET2	10	104421	102220	C	Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p
440	S000003703	ORF	Verified	YJL167W	ERG20	10	105007	106065	W	Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis
442	S000003702	ORF	Verified	YJL166W	QCR8	10	106427	106711	W	Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p
444	S000003701	ORF	Verified	YJL165C	HAL5	10	109454	106887	C	Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters
446	S000003700	ORF	Verified	YJL164C	TPK1	10	111152	109959	C	Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; inhibits filamentous growth
449	S000003699	ORF	Uncharacterized	YJL163C	n.a.	10	113328	111661	C	Hypothetical protein
451	S000003698	ORF	Uncharacterized	YJL162C	JJJ2	10	115624	114176	C	Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
453	S000006557	tRNA	n.a.	tE(UUC)J	n.a.	10	116005	115934	C	tRNA-Glu
455	S000003697	ORF	Uncharacterized	YJL161W	n.a.	10	117240	117782	W	The authentic, non-tagged protein was localized to the mitochondria
457	S000003696	ORF	Uncharacterized	YJL160C	n.a.	10	118820	117957	C	Hypothetical protein
459	S000003695	ORF	Verified	YJL159W	HSP150	10	120444	121607	W	O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation
461	S000003694	ORF	Verified	YJL158C	CIS3	10	122865	122182	C	Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family
463	S000003693	ORF	Verified	YJL157C	FAR1	10	126245	123753	C	Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate
465	S000007613	ORF	Dubious	YJL156W-A	n.a.	10	126521	126742	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
467	S000003692	ORF	Verified	YJL156C	SSY5	10	128870	126807	C	Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
469	S000003691	ORF	Verified	YJL155C	FBP26	10	130561	129203	C	Fructose-2,6-bisphosphatase, required for glucose metabolism
471	S000003690	ORF	Verified	YJL154C	VPS35	10	133853	131019	C	Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps26p and Vps29p that selects cargo proteins for endosome-to-Golgi retrieval
473	S000003689	ORF	Verified	YJL153C	INO1	10	135851	134250	C	Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element
475	S000003688	ORF	Dubious	YJL152W	n.a.	10	136092	136451	W	Hypothetical protein
477	S000003687	ORF	Verified	YJL151C	SNA3	10	136691	136290	C	Integral membrane protein localized to vacuolar intralumenal vesicles, computational analysis of large-scale protein-protein interaction data suggests a possible role in either cell wall synthesis or protein-vacuolar targeting
479	S000003686	ORF	Dubious	YJL150W	n.a.	10	137041	137343	W	Hypothetical protein
481	S000003685	ORF	Uncharacterized	YJL149W	n.a.	10	137297	139288	W	Hypothetical protein; has similarity to F-box proteins
483	S000006508	snoRNA	n.a.	snR128	SNR128	10	139609	139484	C	U14 snoRNA
485	S000006509	snoRNA	n.a.	snR190	SNR190	10	139868	139679	C	U190 snoRNA
487	S000003684	ORF	Verified	YJL148W	RPA34	10	140355	141056	W	RNA polymerase I subunit A34.5
489	S000003683	ORF	Uncharacterized	YJL147C	n.a.	10	142485	141337	C	Hypothetical protein
491	S000003682	ORF	Verified	YJL146W	IDS2	10	143210	144619	W	Protein involved in modulation of Ime2p activity during meiosis, appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation
493	S000003681	ORF	Verified	YJL145W	SFH5	10	145078	145962	W	Putative phosphatidylinositol transfer protein (PITP), exhibits phosphatidylinositol- but not phosphatidylcholine-transfer activity, mainly localized to cytosol and microsomes, similar to Sec14p; may be PITP regulator rather than actual PITP
495	S000003680	ORF	Uncharacterized	YJL144W	n.a.	10	146277	146591	W	Hypothetical protein
497	S000003679	ORF	Verified	YJL143W	TIM17	10	147019	147495	W	Essential constituent of the mitochondrial inner membrane presequence translocase; interacts with Pam18p to recruit the presequence translocase-associated motor (PAM complex) and also required for protein sorting during import
499	S000003678	ORF	Dubious	YJL142C	n.a.	10	148129	147737	C	Hypothetical protein
501	S000003677	ORF	Verified	YJL141C	YAK1	10	150308	147885	C	Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal
503	S000003676	ORF	Verified	YJL140W	RPB4	10	150879	151544	W	RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; dispensable under some environmental conditions; involved in export of mRNA to cytoplasm under stress conditions
505	S000003675	ORF	Verified	YJL139C	YUR1	10	152917	151631	C	Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; located in the Golgi apparatus
507	S000003674	ORF	Verified	YJL138C	TIF2	10	154609	153422	C	Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
509	S000003673	ORF	Verified	YJL137C	GLG2	10	156045	154903	C	Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin
511	S000028806	ORF	Uncharacterized	YJL136W-A	n.a.	10	156087	156170	W	Identified by SAGE
513	S000003672	ORF	Verified	YJL136C	RPS21B	10	157191	156468	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein
516	S000034085	intron	n.a.	n.a.	n.a.	10	157167	156708	C	n.a.
517	S000003671	ORF	Dubious	YJL135W	n.a.	10	157795	158112	W	Hypothetical protein
519	S000003670	ORF	Verified	YJL134W	LCB3	10	158106	159335	W	Long-chain base-1-phosphate phosphatase, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids
521	S000028805	ORF	Uncharacterized	YJL133C-A	n.a.	10	159765	159541	C	ORF, Uncharacterized
523	S000003669	ORF	Verified	YJL133W	MRS3	10	160537	161481	W	Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs4p; functions under low-iron conditions; may transport other cations in addition to iron
525	S000003668	ORF	Uncharacterized	YJL132W	n.a.	10	161832	164084	W	Hypothetical protein
527	S000003667	ORF	Uncharacterized	YJL131C	n.a.	10	165266	164196	C	Hypothetical protein
529	S000003666	ORF	Verified	YJL130C	URA2	10	172285	165641	C	Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP
531	S000003665	ORF	Verified	YJL129C	TRK1	10	177224	173517	C	Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter
533	S000003664	ORF	Verified	YJL128C	PBS2	10	180021	178015	C	MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress
535	S000007612	ORF	Dubious	YJL127W-A	n.a.	10	180112	180228	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
537	S000028522	ORF	Uncharacterized	YJL127C-B	n.a.	10	181628	181470	C	Identified by homology to <i>Ashbya gossypii</i>
539	S000003663	ORF	Verified	YJL127C	SPT10	10	184139	182217	C	Putative histone acetylase, required for transcriptional regulation at core promoters, functions at or near the TATA box
541	S000003662	ORF	Verified	YJL126W	NIT2	10	184420	185343	W	Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member
543	S000003661	ORF	Verified	YJL125C	GCD14	10	186598	185447	C	Subunit of tRNA (1-methyladenosine) methyltransferase, with Gcd10p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
545	S000003660	ORF	Verified	YJL124C	LSM1	10	187564	187046	C	Component of small nuclear ribonucleoprotein complexes involved in mRNA decapping and decay
547	S000003659	ORF	Uncharacterized	YJL123C	n.a.	10	189360	187924	C	Hypothetical protein
549	S000003658	ORF	Uncharacterized	YJL122W	n.a.	10	189636	190163	W	Hypothetical protein
551	S000003656	ORF	Dubious	YJL120W	n.a.	10	190942	191265	W	Hypothetical protein
553	S000003657	ORF	Verified	YJL121C	RPE1	10	191010	190294	C	D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress
555	S000003654	ORF	Uncharacterized	YJL118W	n.a.	10	191559	192218	W	Hypothetical protein
557	S000003655	ORF	Dubious	YJL119C	n.a.	10	191815	191492	C	Hypothetical protein
559	S000003653	ORF	Verified	YJL117W	PHO86	10	192451	193386	W	Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles
561	S000003652	ORF	Verified	YJL116C	NCA3	10	194793	193780	C	Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family
563	S000003651	ORF	Verified	YJL115W	ASF1	10	196206	197045	W	Nucleosome assembly factor, involved in chromatin assembly after DNA replication, anti-silencing protein that causes derepression of silent loci when overexpressed
565	S000006514	tRNA	n.a.	tA(AGC)J	n.a.	10	197304	197232	C	tRNA-Ala
579	S000006536	tRNA	n.a.	tD(GUC)J1	n.a.	10	204652	204723	W	tRNA-Asp
581	S000003648	ORF	Verified	YJL112W	MDV1	10	205222	207366	W	Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats
583	S000003647	ORF	Verified	YJL111W	CCT7	10	207794	209446	W	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
585	S000003646	ORF	Verified	YJL110C	GZF3	10	211494	209839	C	GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p
587	S000003645	ORF	Verified	YJL109C	UTP10	10	217226	211917	C	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
589	S000003644	ORF	Verified	YJL108C	PRM10	10	218773	217622	C	Pheromone-regulated protein, predicted to have 5 transmembrane segments
591	S000003643	ORF	Uncharacterized	YJL107C	n.a.	10	219933	218770	C	Hypothetical protein
593	S000003642	ORF	Verified	YJL106W	IME2	10	221307	223244	W	Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p
595	S000003641	ORF	Verified	YJL105W	SET4	10	224972	226654	W	Protein of unknown function, contains a SET domain
597	S000003640	ORF	Verified	YJL104W	PAM16	10	227244	227693	W	Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam18p; has similarity to J-domain containing proteins
599	S000006501	snoRNA	n.a.	snR37	SNR37	10	228396	228011	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2940
602	S000003639	ORF	Uncharacterized	YJL103C	n.a.	10	230798	228942	C	Hypothetical protein
604	S000003638	ORF	Verified	YJL102W	MEF2	10	231218	233677	W	Mitochondrial elongation factor involved in translational elongation
606	S000006702	tRNA	n.a.	tR(ACG)J	n.a.	10	233856	233928	W	tRNA-Arg
608	S000003637	ORF	Verified	YJL101C	GSH1	10	236273	234237	C	Gamma glutamylcysteine synthetase, catalyzes the first step in the gamma-glutamyl cycle for glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury
610	S000003636	ORF	Verified	YJL100W	LSB6	10	237180	239003	W	Phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
612	S000003635	ORF	Verified	YJL099W	CHS6	10	239331	241571	W	Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p localization
614	S000003634	ORF	Verified	YJL098W	SAP185	10	241999	245175	W	Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p
616	S000003633	ORF	Uncharacterized	YJL097W	n.a.	10	245508	246161	W	Protein required for cell viability
618	S000003632	ORF	Verified	YJL096W	MRPL49	10	246407	246892	W	Mitochondrial ribosomal protein of the large subunit
620	S000003631	ORF	Verified	YJL095W	BCK1	10	247171	251607	W	Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p
622	S000003630	ORF	Verified	YJL094C	KHA1	10	254358	251737	C	Putative K+/H+ antiporter
624	S000003629	ORF	Verified	YJL093C	TOK1	10	256728	254653	C	Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin
626	S000003628	ORF	Verified	YJL092W	HPR5	10	257339	260863	W	DNA helicase and DNA-dependent ATPase involved in DNA repair, required for proper timing of commitment to meiotic recombination and the transition from Meiosis I to Meiosis II; potential Cdc28p substrate
628	S000003627	ORF	Verified	YJL091C	GWT1	10	262468	260996	C	Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors
630	S000003626	ORF	Verified	YJL090C	DPB11	10	264967	262673	C	Essential BRCT repeat protein, required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis, also required for S/M checkpoint control
632	S000003625	ORF	Verified	YJL089W	SIP4	10	265842	268331	W	C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus
634	S000003624	ORF	Verified	YJL088W	ARG3	10	268715	269731	W	Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine
636	S000003623	ORF	Verified	YJL087C	TRL1	10	272401	269918	C	tRNA ligase, required for tRNA splicing; composed of three essential domains containing the phosphodiesterase, polynucleotide kinase, and ligase activities required for ligation; localized at the inner membrane of the nuclear envelope
638	S000003621	ORF	Verified	YJL085W	EXO70	10	272743	274614	W	Essential 70kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
640	S000003622	ORF	Dubious	YJL086C	n.a.	10	272762	272394	C	Protein required for cell viability
642	S000003620	ORF	Verified	YJL084C	n.a.	10	277918	274778	C	Cytoplasmic protein of unknown function that interacts with Pcl7p, phosphorylated in vitro; potential Cdc28p substrate
644	S000003619	ORF	Verified	YJL083W	TAX4	10	278757	280571	W	Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentrations; Irs4p and Tax4p bind and activate the phosphatase Inp51p
646	S000003618	ORF	Verified	YJL082W	IML2	10	281101	283296	W	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus
648	S000003617	ORF	Verified	YJL081C	ARP4	10	285187	283718	C	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
650	S000003616	ORF	Verified	YJL080C	SCP160	10	289142	285474	C	Essential RNA-binding G protein effector of mating response pathway, predominantly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins
652	S000003615	ORF	Verified	YJL079C	PRY1	10	290690	289791	C	Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins
654	S000003614	ORF	Verified	YJL078C	PRY3	10	293897	291252	C	Protein of unknown function, has similarity to Pry1p and Pry2p and to the plant PR-1 class of pathogen related proteins
656	S000028662	ORF	Uncharacterized	YJL077W-B	n.a.	10	293963	294061	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
658	S000028661	ORF	Dubious	YJL077W-A	n.a.	10	294715	294801	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
660	S000003613	ORF	Uncharacterized	YJL077C	ICS3	10	294977	294582	C	Protein of unknown function
662	S000003612	ORF	Verified	YJL076W	NET1	10	295161	298730	W	Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure
665	S000003611	ORF	Dubious	YJL075C	n.a.	10	298792	298376	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene NET1
667	S000003610	ORF	Verified	YJL074C	SMC3	10	302765	299073	C	Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member
669	S000003609	ORF	Verified	YJL073W	JEM1	10	303097	305034	W	DnaJ-like chaperone required for nuclear membrane fusion during mating, localizes to the ER membrane; exhibits genetic interactions with KAR2
671	S000003608	ORF	Verified	YJL072C	PSF2	10	305778	305137	C	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
673	S000003607	ORF	Verified	YJL071W	ARG2	10	306048	307772	W	Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p
675	S000003606	ORF	Uncharacterized	YJL070C	n.a.	10	310553	307887	C	Hypothetical protein
677	S000003605	ORF	Uncharacterized	YJL069C	UTP18	10	312622	310838	C	Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
679	S000003604	ORF	Uncharacterized	YJL068C	n.a.	10	313831	312932	C	Hypothetical protein
681	S000003603	ORF	Dubious	YJL067W	n.a.	10	314000	314350	W	Hypothetical protein
683	S000003602	ORF	Verified	YJL066C	MPM1	10	314788	314030	C	Mitochondrial membrane protein of unknown function, contains no hydrophobic stretches
685	S000003600	ORF	Dubious	YJL064W	n.a.	10	315091	315486	W	Hypothetical protein
687	S000003601	ORF	Verified	YJL065C	DLS1	10	315473	314970	C	Subunit of ISW2/yCHRAC chromatin accessibility complex along with Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing
689	S000003599	ORF	Verified	YJL063C	MRPL8	10	316391	315675	C	Mitochondrial ribosomal protein of the large subunit
691	S000007611	ORF	Uncharacterized	YJL062W-A	n.a.	10	316639	316896	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
693	S000003598	ORF	Verified	YJL062W	LAS21	10	317200	319692	W	Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity
695	S000003597	ORF	Verified	YJL061W	NUP82	10	319932	322073	W	Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p and is required for proper localization of Nup116p in the NPC
697	S000003596	ORF	Verified	YJL060W	BNA3	10	323302	324636	W	Arylformamidase, involved in biosynthesis of nicotinic acid from tryptophan via kynurenine pathway; potential Cdc28p substrate
699	S000003595	ORF	Verified	YJL059W	YHC3	10	324880	326106	W	Homolog of human CLN3; vacuolar/lysosomal membrane protein
701	S000003594	ORF	Verified	YJL058C	BIT61	10	327789	326158	C	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity
703	S000003593	ORF	Uncharacterized	YJL057C	n.a.	10	330037	328034	C	probable serine/threonine kinase
705	S000003592	ORF	Verified	YJL056C	ZAP1	10	332989	330347	C	Zinc-regulated transcription factor, binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc; regulates its own transcription; contains seven zinc-finger domains
707	S000003591	ORF	Uncharacterized	YJL055W	n.a.	10	333273	334010	W	Hypothetical protein
709	S000003590	ORF	Verified	YJL054W	TIM54	10	334181	335617	W	Translocase Inner Membrane, 54kD; Translocase for the insertion of proteins into the mitochondrial inner membrane.
711	S000003589	ORF	Verified	YJL053W	PEP8	10	335814	336953	W	Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport
714	S000007610	ORF	Uncharacterized	YJL052C-A	n.a.	10	337919	337800	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
716	S000003588	ORF	Verified	YJL052W	TDH1	10	338187	339185	W	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
718	S000003587	ORF	Uncharacterized	YJL051W	n.a.	10	339703	342171	W	Protein of unknown function, localized to the bud tip; mRNA is targeted to the bud via the mRNA transport system involving She2p
720	S000003586	ORF	Verified	YJL050W	MTR4	10	342438	345659	W	Dead-box family ATP dependent helicase required for mRNA export from the nucleus; co-factor of the exosome complex, required for 3' end formation of 5.8S rRNA
722	S000003585	ORF	Uncharacterized	YJL049W	n.a.	10	345889	347241	W	Hypothetical protein
724	S000003584	ORF	Uncharacterized	YJL048C	UBX6	10	348553	347363	C	UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline
726	S000028804	ORF	Uncharacterized	YJL047C-A	n.a.	10	349094	348960	C	ORF, Uncharacterized
728	S000006451	snoRNA	n.a.	snR60	SNR60	10	349149	349046	C	guides 2'-O-methylation on large subunit rRNA at A815 and G906; small nucleolar RNA snR60
730	S000003583	ORF	Verified	YJL047C	RTT101	10	352024	349496	C	Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p
732	S000003582	ORF	Uncharacterized	YJL046W	n.a.	10	352176	353531	W	Hypothetical protein
734	S000006781	tRNA	n.a.	tY(GUA)J1	SUP7	10	354160	354248	W	tRNA-Tyr
735	S000032080	intron	n.a.	n.a.	n.a.	10	354199	354212	W	n.a.
740	S000006714	tRNA	n.a.	tR(UCU)J1	n.a.	10	355290	355361	W	tRNA-Arg
742	S000006537	tRNA	n.a.	tD(GUC)J2	n.a.	10	355372	355443	W	tRNA-Asp
744	S000003581	ORF	Uncharacterized	YJL045W	n.a.	10	355940	357844	W	Similar to SDH1
746	S000003580	ORF	Verified	YJL044C	GYP6	10	359592	358216	C	GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport
748	S000003579	ORF	Uncharacterized	YJL043W	n.a.	10	360046	360819	W	Hypothetical protein
750	S000003578	ORF	Verified	YJL042W	MHP1	10	361165	365361	W	Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins
752	S000003577	ORF	Verified	YJL041W	NSP1	10	365700	368289	W	Essential component of the nuclear pore complex, which mediates nuclear import and export
755	S000034260	intron	n.a.	n.a.	n.a.	10	365701	365818	W	n.a.
756	S000003576	ORF	Verified	YJL039C	NUP192	10	373715	368664	C	Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery of nuclear pores, homologous to human p205
759	S000006538	tRNA	n.a.	tD(GUC)J3	n.a.	10	374411	374340	C	tRNA-Asp
761	S000006715	tRNA	n.a.	tR(UCU)J2	n.a.	10	374493	374422	C	tRNA-Arg
765	S000003575	ORF	Uncharacterized	YJL038C	n.a.	10	375690	375031	C	Hypothetical protein
767	S000003574	ORF	Uncharacterized	YJL037W	n.a.	10	376578	377252	W	Hypothetical protein
770	S000006759	tRNA	n.a.	tV(AAC)J	n.a.	10	378276	378349	W	tRNA-Val
772	S000003573	ORF	Verified	YJL036W	SNX4	10	378741	380012	W	Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX domain; forms complex with Snx41p and Atg20p
774	S000003572	ORF	Verified	YJL035C	TAD2	10	380917	380165	C	Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs
776	S000003571	ORF	Verified	YJL034W	KAR2	10	381243	383291	W	ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p
778	S000003570	ORF	Verified	YJL033W	HCA4	10	383753	386065	W	Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis
780	S000003569	ORF	Dubious	YJL032W	n.a.	10	386264	386578	W	Protein required for cell viability
782	S000003568	ORF	Verified	YJL031C	BET4	10	387354	386284	C	Alpha subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
785	S000030061	intron	n.a.	n.a.	n.a.	10	387351	387265	C	n.a.
786	S000003567	ORF	Verified	YJL030W	MAD2	10	387573	388163	W	Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p
788	S000003566	ORF	Verified	YJL029C	VPS53	10	390769	388301	C	Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting
790	S000006661	tRNA	n.a.	tM(CAU)J1	EMT5	10	391031	390959	C	tRNA that accepts methionine; functions in translational elongation but not translational initiation
792	S000003565	ORF	Dubious	YJL028W	n.a.	10	391227	391562	W	Hypothetical protein
794	S000003564	ORF	Uncharacterized	YJL027C	n.a.	10	392165	391749	C	Hypothetical protein
796	S000003563	ORF	Verified	YJL026W	RNR2	10	392320	393519	W	Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
798	S000028660	ORF	Dubious	YJL026C-A	n.a.	10	393203	392982	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
800	S000003562	ORF	Verified	YJL025W	RRN7	10	393883	395427	W	involved in the transcription of 35S rRNA genes by RNA polymerase I; member of yeast Pol I core factor (CF) also composed of Rrn11p, Rrn6p and TATA-binding protein
802	S000003561	ORF	Verified	YJL024C	APS3	10	396508	395847	C	Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function
805	S000036077	intron	n.a.	n.a.	n.a.	10	396486	396410	C	n.a.
806	S000006583	tRNA	n.a.	tG(GCC)J1	n.a.	10	396712	396642	C	tRNA-Gly
808	S000003559	ORF	Dubious	YJL022W	n.a.	10	398025	398333	W	Hypothetical protein
810	S000003560	ORF	Verified	YJL023C	PET130	10	398314	397271	C	Protein required for respiratory growth
812	S000028659	ORF	Dubious	YJL020W-A	n.a.	10	400897	401154	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
814	S000003557	ORF	Verified	YJL020C	BBC1	10	402326	398853	C	Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches
816	S000003556	ORF	Verified	YJL019W	MPS3	10	402813	404861	W	Essential integral membrane protein required for spindle pole body duplication and for nuclear fusion, localizes to the spindle pole body half bridge, interacts with DnaJ-like chaperone Jem1p and with centrin homolog Cdc31p
818	S000003553	ORF	Uncharacterized	YJL016W	n.a.	10	405504	407189	W	Hypothetical protein
820	S000003552	ORF	Dubious	YJL015C	n.a.	10	407432	407058	C	Protein required for cell viability
822	S000003551	ORF	Verified	YJL014W	CCT3	10	407473	409077	W	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
824	S000003550	ORF	Verified	YJL013C	MAD3	10	410955	409408	C	Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; interacts physically with the spindle checkpoint proteins Bub3p and Mad2p
826	S000003549	ORF	Verified	YJL012C	VTC4	10	413314	411149	C	Phosphate metabolism; transcription is regulated by PHO system; polyphosphate synthetase (putative)
828	S000003548	ORF	Verified	YJL011C	RPC17	10	414685	414200	C	RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex
830	S000006625	tRNA	n.a.	tK(CUU)J	n.a.	10	414881	414953	W	tRNA-Lys
832	S000006773	tRNA	n.a.	tW(CCA)J	n.a.	10	415951	415846	C	tRNA-Trp
833	S000033314	intron	n.a.	n.a.	n.a.	10	415915	415882	C	n.a.
840	S000003547	ORF	Uncharacterized	YJL010C	n.a.	10	419477	417477	C	Essential nucleolar protein required for 18S rRNA synthesis
842	S000003546	ORF	Dubious	YJL009W	n.a.	10	419770	420096	W	Protein required for cell viability
844	S000003545	ORF	Verified	YJL008C	CCT8	10	421578	419872	C	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
848	S000006662	tRNA	n.a.	tM(CAU)J2	EMT3	10	422852	422924	W	tRNA that accepts methionine; functions in translational elongation but not translational initiation
850	S000003544	ORF	Dubious	YJL007C	n.a.	10	422927	422613	C	Hypothetical protein
852	S000003543	ORF	Verified	YJL006C	CTK2	10	424024	423053	C	Beta subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing; has similarity to cyclins
854	S000006650	tRNA	n.a.	tL(UAA)J	SUP51	10	424430	424347	C	tRNA-Leu
856	S000003542	ORF	Verified	YJL005W	CYR1	10	425072	431152	W	Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; involved in cell cycle control and glucose and nitrogen repression of sporulation
858	S000003541	ORF	Verified	YJL004C	SYS1	10	432115	431504	C	Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation
860	S000003540	ORF	Verified	YJL003W	COX16	10	432559	432915	W	Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase
862	S000003539	ORF	Verified	YJL002C	OST1	10	434566	433136	C	Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins
864	S000003538	ORF	Verified	YJL001W	PRE3	10	435078	435841	W	20S proteasome beta-type subunit, responsible for cleavage after acidic residues in peptides
867	S000035911	intron	n.a.	n.a.	n.a.	10	435143	435258	W	n.a.
872	S000003761	ORF	Verified	YJR001W	AVT1	10	436717	438525	W	Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
874	S000003762	ORF	Verified	YJR002W	MPP10	10	438779	440560	W	Component of the SSU processome, which is required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p
877	S000003763	ORF	Uncharacterized	YJR003C	n.a.	10	442527	440908	C	Hypothetical protein
879	S000003764	ORF	Verified	YJR004C	SAG1	10	444775	442823	C	Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor
881	S000003765	ORF	Verified	YJR005W	APL1	10	445837	447939	W	Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex
883	S000028523	ORF	Uncharacterized	YJR005C-A	n.a.	10	448672	448391	C	Identified by homology to <i>Ashbya gossypii</i>
885	S000003766	ORF	Verified	YJR006W	HYS2	10	449116	450579	W	DNA polymerase III (delta) 55 kDa subunit, essential for cell viability; involved in DNA replication and DNA repair
887	S000003767	ORF	Verified	YJR007W	SUI2	10	450934	451848	W	Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP
889	S000003768	ORF	Uncharacterized	YJR008W	n.a.	10	452344	453360	W	Hypothetical protein
892	S000003769	ORF	Verified	YJR009C	TDH2	10	454595	453597	C	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
894	S000003771	ORF	Verified	YJR010W	MET3	10	456153	457688	W	ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism
896	S000003770	ORF	Verified	YJR010C-A	SPC1	10	458275	457991	C	Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex
899	S000003772	ORF	Uncharacterized	YJR011C	n.a.	10	459340	458555	C	Hypothetical protein
901	S000003774	ORF	Uncharacterized	YJR013W	GPI14	10	460296	461507	W	Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M
903	S000003773	ORF	Dubious	YJR012C	n.a.	10	460332	459709	C	Protein required for cell viability
905	S000003775	ORF	Uncharacterized	YJR014W	n.a.	10	461743	462339	W	Hypothetical protein
907	S000003776	ORF	Uncharacterized	YJR015W	n.a.	10	462635	464167	W	Hypothetical protein
909	S000003777	ORF	Verified	YJR016C	ILV3	10	466122	464365	C	Dihydroxyacid dehydratase, catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids
911	S000003779	ORF	Dubious	YJR018W	n.a.	10	466700	467062	W	Hypothetical protein
913	S000003778	ORF	Verified	YJR017C	ESS1	10	466947	466435	C	Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain
915	S000003781	ORF	Dubious	YJR020W	n.a.	10	467915	468247	W	Hypothetical protein
917	S000003780	ORF	Verified	YJR019C	TES1	10	468195	467146	C	Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids
919	S000003782	ORF	Verified	YJR021C	REC107	10	469493	468469	C	Protein involved in early stages of meiotic recombination; involved in altering chromatin structure at DNA double-stranded break sites and in coordination between the initiation of recombination and the first division of meiosis
922	S000030252	intron	n.a.	n.a.	n.a.	10	469177	469098	C	n.a.
923	S000003783	ORF	Verified	YJR022W	LSM8	10	469698	470027	W	Component of small nuclear ribonucleoprotein complexes involved in RNA processing and splicing
925	S000003784	ORF	Dubious	YJR023C	n.a.	10	470119	469718	C	Protein required for cell viability
927	S000003785	ORF	Uncharacterized	YJR024C	n.a.	10	470878	470144	C	Hypothetical protein
929	S000003786	ORF	Verified	YJR025C	BNA1	10	471585	471052	C	3-hydroxyanthranilic acid dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
948	S000003791	ORF	Uncharacterized	YJR030C	n.a.	10	486110	483873	C	Hypothetical protein
950	S000003792	ORF	Verified	YJR031C	GEA1	10	490726	486500	C	Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea2p
952	S000003793	ORF	Verified	YJR032W	CPR7	10	490995	492176	W	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity
954	S000003794	ORF	Verified	YJR033C	RAV1	10	496365	492292	C	Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate
956	S000003795	ORF	Verified	YJR034W	PET191	10	496597	496923	W	Protein required for assembly of cytochrome c oxidase
958	S000003796	ORF	Verified	YJR035W	RAD26	10	497269	500526	W	Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSB protein
960	S000003798	ORF	Dubious	YJR037W	n.a.	10	503016	503399	W	Hypothetical protein
962	S000003797	ORF	Verified	YJR036C	HUL4	10	503305	500627	C	Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability
964	S000003800	ORF	Uncharacterized	YJR039W	n.a.	10	503850	507215	W	Hypothetical protein
966	S000003799	ORF	Dubious	YJR038C	n.a.	10	503986	503624	C	Hypothetical protein
968	S000003801	ORF	Verified	YJR040W	GEF1	10	507660	509999	W	Chloride channel localized to late- or post-Golgi vesicles, involved in iron metabolism; highly homologous to voltage-gated chloride channels in vertebrates
970	S000003802	ORF	Verified	YJR041C	URB2	10	513677	510153	C	Nucleolar protein required for normal metabolism of the rRNA primary transcript, proposed to be involved in ribosome biogenesis
972	S000003803	ORF	Verified	YJR042W	NUP85	10	513969	516203	W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for assembly of the subcomplex and also for formation of the nucleocytoplasmic Gsp1p concentration gradient that plays a role in nuclear trafficking
974	S000003804	ORF	Verified	YJR043C	POL32	10	517427	516375	C	Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Pol31p, PCNA (Pol30p), and Pol1p
976	S000006663	tRNA	n.a.	tM(CAU)J3	IMT3	10	517798	517727	C	Initiator methionine tRNA, tRNA(IMet), one of four initiator methionine tRNA genes in yeast that are functional for translation
979	S000003805	ORF	Verified	YJR044C	VPS55	10	519099	518677	C	Late endosomal protein involved in late endosome to vacuole trafficking; functional homolog of human obesity receptor gene-related protein (OB-RGRP)
981	S000003806	ORF	Verified	YJR045C	SSC1	10	521516	519552	C	Mitochondrial matrix ATPase that is a subunit of the presequence translocase-associated protein import motor (PAM); involved in protein translocation into the matrix and protein folding; member of the heat shock protein 70 (HSP70) family
983	S000003807	ORF	Verified	YJR046W	TAH11	10	521962	523776	W	DNA replication licensing factor, required for pre-replication complex assembly
985	S000006727	tRNA	n.a.	tS(AGA)J	n.a.	10	524007	523926	C	tRNA-Ser
987	S000003808	ORF	Verified	YJR047C	ANB1	10	525295	524822	C	Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions
989	S000003809	ORF	Verified	YJR048W	CYC1	10	526249	526578	W	Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
991	S000003810	ORF	Verified	YJR049C	UTR1	10	528390	526798	C	NAD kinase, active as a hexamer; enhances the activity of ferric reductase (Fre1p)
993	S000003811	ORF	Verified	YJR050W	ISY1	10	528611	529318	W	Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest
995	S000003812	ORF	Verified	YJR051W	OSM1	10	529775	531280	W	Fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity
998	S000006584	tRNA	n.a.	tG(GCC)J2	n.a.	10	531742	531812	W	tRNA-Gly
1000	S000003813	ORF	Verified	YJR052W	RAD7	10	531976	533673	W	Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4)
1002	S000003814	ORF	Verified	YJR053W	BFA1	10	533941	535665	W	Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis
1004	S000003815	ORF	Uncharacterized	YJR054W	n.a.	10	535970	537463	W	Vacuolar protein of unknown function; potential Cdc28p substrate
1008	S000006707	tRNA	n.a.	tR(CCU)J	HSX1	10	538469	538540	W	Low abundance arginine tRNA; required for growth on nonfermentable carbon sources at high temperatures; for the synthesis of Ssc1p, a heat shock protein; and for Ty1 retrotransposition through the regulation of translational frameshifting
1010	S000003816	ORF	Verified	YJR055W	HIT1	10	538686	539180	W	Protein of unknown function, required for growth at high temperature
1015	S000006539	tRNA	n.a.	tD(GUC)J4	n.a.	10	541422	541493	W	tRNA-Asp
1017	S000003817	ORF	Uncharacterized	YJR056C	n.a.	10	542416	541706	C	Hypothetical protein
1019	S000006782	tRNA	n.a.	tY(GUA)J2	SUP4	10	542958	542870	C	tRNA-Tyr
1020	S000032087	intron	n.a.	n.a.	n.a.	10	542919	542906	C	n.a.
1024	S000003818	ORF	Verified	YJR057W	CDC8	10	543976	544626	W	Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p
1026	S000003819	ORF	Verified	YJR058C	APS2	10	545089	544646	C	Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex
1028	S000003820	ORF	Verified	YJR059W	PTK2	10	545701	548157	W	Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake
1030	S000003821	ORF	Verified	YJR060W	CBF1	10	548673	549728	W	Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA
1032	S000003822	ORF	Uncharacterized	YJR061W	n.a.	10	550425	553232	W	Hypothetical protein
1034	S000003823	ORF	Verified	YJR062C	NTA1	10	554763	553390	C	Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation
1036	S000003824	ORF	Verified	YJR063W	RPA12	10	555109	555486	W	RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex
1038	S000003825	ORF	Verified	YJR064W	CCT5	10	555828	557516	W	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
1040	S000003826	ORF	Verified	YJR065C	ARP3	10	559072	557723	C	Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity
1042	S000003827	ORF	Verified	YJR066W	TOR1	10	559330	566742	W	PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis
1044	S000003828	ORF	Verified	YJR067C	YAE1	10	567358	566933	C	Essential protein of unknown function
1046	S000003829	ORF	Verified	YJR068W	RFC2	10	567557	568618	W	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
1048	S000003830	ORF	Verified	YJR069C	HAM1	10	569313	568720	C	Protein of unknown function that is involved in DNA repair; mutant is sensitive to the base analog, 6-N-hydroxylaminopurine, while gene disruption does not increase the rate of spontaneous mutagenesis
1050	S000003832	ORF	Dubious	YJR071W	n.a.	10	570319	570687	W	Hypothetical protein
1052	S000003831	ORF	Verified	YJR070C	LIA1	10	570512	569535	C	Protein with a possible role in microtubule function; complements S. pombe mmd1 mutation affecting mitochondrial distribution although not required for this process in S. cerevisiae; binds to Hyp2p (eIF5A); contains HEAT-like repeats
1054	S000003833	ORF	Verified	YJR072C	NPA3	10	572038	570881	C	Cytoplasmic protein required for cell viability, identified by association with pre-ribosomal particles
1056	S000003834	ORF	Verified	YJR073C	OPI3	10	572849	572229	C	Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis
1058	S000003835	ORF	Verified	YJR074W	MOG1	10	573009	573665	W	Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p
1060	S000003836	ORF	Verified	YJR075W	HOC1	10	573895	575085	W	Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localized complex that also contains Anp1p, Mnn9p, Mnn11p, and Mnn10p; identified as a suppressor of a cell lysis sensitive pkc1-371 allele
1062	S000003837	ORF	Verified	YJR076C	CDC11	10	576515	575268	C	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
1064	S000003838	ORF	Verified	YJR077C	MIR1	10	578104	577169	C	Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2 under normal conditions
1066	S000003839	ORF	Verified	YJR078W	BNA2	10	578774	580135	W	Tryptophan 2,3-dioxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
1068	S000003840	ORF	Uncharacterized	YJR079W	n.a.	10	580119	581153	W	Hypothetical protein
1071	S000036626	intron	n.a.	n.a.	n.a.	10	580262	580966	W	n.a.
1072	S000003841	ORF	Uncharacterized	YJR080C	n.a.	10	581530	580346	C	The authentic, non-tagged protein was localized to the mitochondria
1074	S000003842	ORF	Uncharacterized	YJR082C	EAF6	10	582169	581828	C	Esa1p-associated factor, subunit of the NuA4 acetyltransferase complex
1076	S000003843	ORF	Uncharacterized	YJR083C	ACF4	10	583451	582522	C	Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate
1078	S000003844	ORF	Verified	YJR084W	CSN12	10	583647	584918	W	Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
1080	S000003845	ORF	Uncharacterized	YJR085C	n.a.	10	585351	585034	C	Hypothetical protein
1082	S000003846	ORF	Verified	YJR086W	STE18	10	585982	586314	W	G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling
1084	S000003847	ORF	Dubious	YJR087W	n.a.	10	586314	586664	W	Hypothetical protein
1086	S000003848	ORF	Uncharacterized	YJR088C	n.a.	10	587287	586409	C	Hypothetical protein
1088	S000003849	ORF	Verified	YJR089W	BIR1	10	587632	590496	W	Protein involved in cell cycle regulation and chromosome segregation, contains BIR (Baculovirus Inhibitor of apoptosis Repeat) domain
1090	S000003850	ORF	Verified	YJR090C	GRR1	10	594241	590786	C	F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p and Cln2p degradation; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, and morphogenesis
1092	S000003851	ORF	Verified	YJR091C	JSN1	10	598250	594975	C	Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells
1094	S000003852	ORF	Verified	YJR092W	BUD4	10	598649	602995	W	Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate
1096	S000003853	ORF	Verified	YJR093C	FIP1	10	604120	603137	C	Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity
1098	S000003854	ORF	Verified	YJR094C	IME1	10	605568	604486	C	Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p
1100	S000003855	ORF	Verified	YJR094W-A	RPL43B	10	608222	608775	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein
1103	S000034759	intron	n.a.	n.a.	n.a.	10	608224	608498	W	n.a.
1104	S000003856	ORF	Verified	YJR095W	SFC1	10	609690	610658	W	Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization
1106	S000003857	ORF	Uncharacterized	YJR096W	n.a.	10	611112	611960	W	Protein with similarity to aldo-keto reductases
1108	S000003858	ORF	Verified	YJR097W	JJJ3	10	612330	612848	W	Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein
1111	S000003859	ORF	Uncharacterized	YJR098C	n.a.	10	615070	613103	C	Hypothetical protein
1113	S000003860	ORF	Verified	YJR099W	YUH1	10	615490	616200	W	Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p
1115	S000003861	ORF	Uncharacterized	YJR100C	n.a.	10	617248	616265	C	Hypothetical protein
1117	S000006654	tRNA	n.a.	tL(UAG)J	n.a.	10	617833	617933	W	tRNA-Leu
1118	S000035855	intron	n.a.	n.a.	n.a.	10	617871	617889	W	n.a.
1121	S000003862	ORF	Verified	YJR101W	RSM26	10	618148	618948	W	Mitochondrial ribosomal protein of the small subunit
1123	S000003863	ORF	Verified	YJR102C	VPS25	10	619679	619071	C	Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome
1125	S000003864	ORF	Verified	YJR103W	URA8	10	620668	622362	W	Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis
1127	S000003865	ORF	Verified	YJR104C	SOD1	10	622927	622463	C	Cu, Zn superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans
1129	S000003866	ORF	Verified	YJR105W	ADO1	10	623494	624516	W	Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle
1131	S000003867	ORF	Verified	YJR106W	ECM27	10	624751	626928	W	Non-essential protein of unknown function
1133	S000003868	ORF	Uncharacterized	YJR107W	n.a.	10	627254	628240	W	Hypothetical protein
1135	S000003869	ORF	Uncharacterized	YJR108W	ABM1	10	628627	628998	W	Protein of unknown function, required for normal microtubule organization
1137	S000003870	ORF	Verified	YJR109C	CPA2	10	632856	629500	C	Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor
1139	S000003871	ORF	Verified	YJR110W	YMR1	10	633530	635596	W	Phosphatidylinositol 3-phosphate [PI(3)P] phosphatase, regulates the localization and levels of PI(3)P; involved in cytoplasm to vacuole (CVT) transport; has similarity to the conserved myotubularin dual specificity phosphatase family
1141	S000003872	ORF	Uncharacterized	YJR111C	n.a.	10	636621	635770	C	Hypothetical protein
1143	S000003873	ORF	Verified	YJR112W	NNF1	10	636945	637550	W	Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation
1145	S000028513	ORF	Uncharacterized	YJR112W-A	n.a.	10	637705	638083	W	Identified based on homology to <i>Ashbya gossypii</i>
1148	S000030279	intron	n.a.	n.a.	n.a.	10	637725	637773	W	n.a.
1149	S000003875	ORF	Uncharacterized	YJR114W	n.a.	10	638574	638966	W	Protein that may be involved in survival during stationary phase, substrate for the N-myristoyltransferase Nmt1p
1151	S000003874	ORF	Verified	YJR113C	RSM7	10	638890	638147	C	Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein
1153	S000003876	ORF	Uncharacterized	YJR115W	n.a.	10	639857	640366	W	Hypothetical protein
1155	S000003877	ORF	Uncharacterized	YJR116W	n.a.	10	640740	641579	W	Hypothetical protein
1157	S000003878	ORF	Verified	YJR117W	STE24	10	641922	643283	W	Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans
1159	S000003879	ORF	Verified	YJR118C	ILM1	10	644016	643405	C	Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth
1161	S000003880	ORF	Uncharacterized	YJR119C	n.a.	10	646405	644219	C	Hypothetical protein
1163	S000003881	ORF	Uncharacterized	YJR120W	n.a.	10	647041	647391	W	Hypothetical protein
1165	S000003882	ORF	Verified	YJR121W	ATP2	10	647522	649057	W	Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
1167	S000003883	ORF	Verified	YJR122W	CAF17	10	649691	651184	W	Mitochondrial protein that interacts with Ccr4p in the two-hybrid system; 3'-untranslated region contains a putative mRNA localization element common to genes encoding mitochondrial proteins
1169	S000003884	ORF	Verified	YJR123W	RPS5	10	651816	652493	W	Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins
1172	S000003885	ORF	Uncharacterized	YJR124C	n.a.	10	654153	652807	C	Hypothetical protein
1174	S000003886	ORF	Verified	YJR125C	ENT3	10	655878	654652	C	Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p
1176	S000003887	ORF	Verified	YJR126C	VPS70	10	658604	656169	C	Protein of unknown function involved in vacuolar protein sorting
1178	S000003889	ORF	Dubious	YJR128W	n.a.	10	662836	663195	W	Hypothetical protein
1180	S000003888	ORF	Verified	YJR127C	ZMS1	10	662974	658832	C	Zinc-finger protein that localizes to the nucleus, putative transcriptional regulator of ALD6
1182	S000006492	snoRNA	n.a.	snR3	SNR3	10	663663	663857	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at positions 2128, 2132, and 2263
1184	S000003890	ORF	Uncharacterized	YJR129C	n.a.	10	664934	663915	C	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
1186	S000003891	ORF	Verified	YJR130C	STR2	10	667052	665133	C	Cystathionine gamma-synthase, converts cysteine into cystathionine
1188	S000003892	ORF	Verified	YJR131W	MNS1	10	667559	669208	W	Alpha-1,2-mannosidase involved in N-linked oligosaccharide biosynthesis; catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc; integral to the ER membrane
1190	S000003893	ORF	Verified	YJR132W	NMD5	10	669437	672583	W	Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog
1192	S000003894	ORF	Verified	YJR133W	XPT1	10	672906	673535	W	Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine
1194	S000003895	ORF	Verified	YJR134C	SGM1	10	675767	673644	C	Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus
1196	S000003896	ORF	Verified	YJR135C	MCM22	10	676693	675974	C	Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner
1198	S000007348	ORF	Verified	YJR135W-A	TIM8	10	676886	677149	W	Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; homolog of human DDP1 (deafness dystonia peptide 1) which is mutated in the X-linked Mohr-Tranebjaerg syndrome
1200	S000003897	ORF	Uncharacterized	YJR136C	n.a.	10	678621	677356	C	Hypothetical protein
1202	S000003898	ORF	Verified	YJR137C	ECM17	10	683200	678872	C	Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine
1205	S000003899	ORF	Verified	YJR138W	IML1	10	684482	689236	W	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane
1207	S000003900	ORF	Verified	YJR139C	HOM6	10	690439	689360	C	Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions
1209	S000028666	ORF	Dubious	YJR140W-A	n.a.	10	690876	691025	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
1211	S000003901	ORF	Verified	YJR140C	HIR3	10	695611	690665	C	Transcriptional corepressor involved in the cell cycle-regulated transcription of histone genes HTA1, HTB1, HHT1, and HHT2; involved in position-dependent gene silencing and nucleosome reassembly
1213	S000003902	ORF	Uncharacterized	YJR141W	n.a.	10	695821	696864	W	Protein required for cell viability
1215	S000003903	ORF	Uncharacterized	YJR142W	n.a.	10	697056	698084	W	Hypothetical protein
1217	S000003904	ORF	Verified	YJR143C	PMT4	10	700529	698241	C	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals
1219	S000003905	ORF	Verified	YJR144W	MGM101	10	700797	701606	W	Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage
1221	S000003906	ORF	Verified	YJR145C	RPS4A	10	702983	701942	C	Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
1224	S000034117	intron	n.a.	n.a.	n.a.	10	702969	702714	C	n.a.
1225	S000003907	ORF	Dubious	YJR146W	n.a.	10	703800	704153	W	Hypothetical protein
1227	S000003908	ORF	Verified	YJR147W	HMS2	10	704111	705187	W	Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant
1229	S000003909	ORF	Verified	YJR148W	BAT2	10	705659	706789	W	Cytosolic branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase
1231	S000003910	ORF	Uncharacterized	YJR149W	n.a.	10	707075	708289	W	Hypothetical protein
1233	S000003911	ORF	Verified	YJR150C	DAN1	10	709622	708726	C	Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
1236	S000003912	ORF	Verified	YJR151C	DAN4	10	715655	712170	C	Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
1238	S000028557	ORF	Uncharacterized	YJR151W-A	n.a.	10	717495	717545	W	Identified by fungal homology and RT-PCR
1240	S000003913	ORF	Verified	YJR152W	DAL5	10	719581	721212	W	Allantoin permease; ureidosuccinate permease; expression is constitutive but sensitive to nitrogen catabolite repression
1242	S000003914	ORF	Verified	YJR153W	PGU1	10	722730	723815	W	Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins
1244	S000003915	ORF	Uncharacterized	YJR154W	n.a.	10	725699	726739	W	Hypothetical protein
1246	S000003916	ORF	Verified	YJR155W	AAD10	10	727320	728186	W	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
1248	S000003917	ORF	Verified	YJR156C	THI11	10	729511	728489	C	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
1251	S000003918	ORF	Dubious	YJR157W	n.a.	10	730430	730792	W	Hypothetical protein
1253	S000003919	ORF	Verified	YJR158W	HXT16	10	732355	734058	W	Protein of unknown function with similarity to hexose transporter family members, expression is repressed by high levels of glucose
1255	S000003920	ORF	Verified	YJR159W	SOR1	10	735959	737032	W	Sorbitol dehydrogenase; expression is induced in the presence of sorbitol
1258	S000003921	ORF	Verified	YJR160C	MPH3	10	739731	737923	C	Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication
1260	S000003922	ORF	Verified	YJR161C	COS5	10	743914	742763	C	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
1267	S000003923	ORF	Dubious	YJR162C	n.a.	10	745176	744826	C	Hypothetical protein
1274	S000001708	ORF	Dubious	YKL225W	n.a.	11	452	799	W	Hypothetical protein
1279	S000001707	ORF	Uncharacterized	YKL224C	n.a.	11	2182	1811	C	Hypothetical protein
1281	S000001706	ORF	Dubious	YKL223W	n.a.	11	2390	2722	W	Hypothetical protein
1283	S000001705	ORF	Uncharacterized	YKL222C	n.a.	11	5621	3504	C	Hypothetical protein
1285	S000001704	ORF	Verified	YKL221W	MCH2	11	6108	7529	W	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
1287	S000001703	ORF	Verified	YKL220C	FRE2	11	11227	9092	C	Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels
1289	S000001702	ORF	Verified	YKL219W	COS9	11	14485	15708	W	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
1291	S000001701	ORF	Verified	YKL218C	SRY1	11	18339	17359	C	3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate
1293	S000001700	ORF	Verified	YKL217W	JEN1	11	22234	24084	W	Lactate transporter, required for uptake of lactate and pyruvate; expression is derepressed by transcriptional activator Cat8p under nonfermentative growth conditions, and repressed in the presence of glucose, fructose, and mannose
1295	S000001699	ORF	Verified	YKL216W	URA1	11	25216	26160	W	Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid
1297	S000001698	ORF	Uncharacterized	YKL215C	n.a.	11	30688	26828	C	Hypothetical protein
1299	S000001697	ORF	Verified	YKL214C	YRA2	11	31694	31083	C	Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus
1301	S000001696	ORF	Verified	YKL213C	DOA1	11	34108	31961	C	WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase
1303	S000001695	ORF	Verified	YKL212W	SAC1	11	34544	36415	W	Lipid phosphoinositide phosphatase of the ER and Golgi, involved in protein trafficking and secretion
1305	S000001694	ORF	Verified	YKL211C	TRP3	11	38154	36700	C	Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p
1307	S000006455	snoRNA	n.a.	snR64	SNR64	11	38812	38912	W	guides 2'-O-methylation on large subunit rRNA at C2335; small nucleolar RNA snR64
1309	S000001693	ORF	Verified	YKL210W	UBA1	11	39164	42238	W	Ubiquitin activating enzyme, involved in ubiquitin-mediated protein degradation and essential for viability
1311	S000001692	ORF	Verified	YKL209C	STE6	11	46296	42424	C	ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport, contains 12 transmembrane domains and two ATP binding domains, expressed only in MATa cells
1313	S000006748	tRNA	n.a.	tT(CGU)K	TRT2	11	46807	46736	C	tRNA threonine 2; tRNA-Thr
1315	S000001691	ORF	Verified	YKL208W	CBT1	11	47158	47973	W	Subunit of complex involved in processing of the 3' end of cytochrome b pre-mRNA; involved in RNA splicing
1317	S000001690	ORF	Uncharacterized	YKL207W	n.a.	11	48108	48956	W	Hypothetical protein
1319	S000001689	ORF	Uncharacterized	YKL206C	n.a.	11	49810	49007	C	Hypothetical protein
1321	S000001688	ORF	Verified	YKL205W	LOS1	11	50052	53354	W	Nuclear pore protein involved in nuclear export of pre-tRNA
1323	S000001687	ORF	Verified	YKL204W	EAP1	11	53705	55603	W	eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade
1325	S000001686	ORF	Verified	YKL203C	TOR2	11	63360	55936	C	PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis
1327	S000001685	ORF	Dubious	YKL202W	n.a.	11	63822	64403	W	Hypothetical protein
1329	S000001684	ORF	Verified	YKL201C	MNN4	11	67467	63931	C	Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases
1331	S000001681	ORF	Verified	YKL198C	PTK1	11	70223	68274	C	Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein
1333	S000001680	ORF	Verified	YKL197C	PEX1	11	73870	70739	C	AAA-family ATPase peroxin required for peroxisome biogenesis, contains two 230 amino acid ATP-binding AAA cassettes, upregulated in anaerobiosis; Pex1p and Pex6p interact via their N-terminal AAA-cassettes
1336	S000006671	tRNA	n.a.	tN(GUU)K	n.a.	11	74629	74702	W	tRNA-Asn
1338	S000001679	ORF	Verified	YKL196C	YKT6	11	75539	74937	C	v-SNARE (synaptobrevin) essential for endoplasmic reticulum-Golgi transport; has similarity to Sec22p, Snc1p, and Snc2p
1340	S000001678	ORF	Verified	YKL195W	MIA40	11	75826	77037	W	Essential protein of the mitochondrial intermembrane space, involved in import and assembly of intermembrane space proteins
1342	S000001677	ORF	Verified	YKL194C	MST1	11	78651	77263	C	Mitochondrial threonyl-tRNA synthetase
1344	S000001676	ORF	Verified	YKL193C	SDS22	11	79887	78871	C	Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis
1346	S000001675	ORF	Verified	YKL192C	ACP1	11	80542	80165	C	Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p
1348	S000001674	ORF	Verified	YKL191W	DPH2	11	81040	82644	W	Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p
1350	S000001673	ORF	Verified	YKL190W	CNB1	11	82952	83555	W	Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1
1353	S000029991	intron	n.a.	n.a.	n.a.	11	83004	83079	W	n.a.
1355	S000006651	tRNA	n.a.	tL(UAA)K	n.a.	11	84213	84296	W	tRNA-Leu
1357	S000001672	ORF	Verified	YKL189W	HYM1	11	84709	85908	W	Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response
1359	S000001671	ORF	Verified	YKL188C	PXA2	11	88791	86230	C	Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins
1361	S000001670	ORF	Uncharacterized	YKL187C	n.a.	11	91541	89289	C	Hypothetical protein
1363	S000001669	ORF	Verified	YKL186C	MTR2	11	93303	92749	C	mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA
1365	S000001668	ORF	Verified	YKL185W	ASH1	11	94504	96270	W	Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate
1367	S000001667	ORF	Verified	YKL184W	SPE1	11	96762	98162	W	Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines
1369	S000028558	ORF	Uncharacterized	YKL183C-A	n.a.	11	98612	98400	C	Identified by fungal homology and RT-PCR
1371	S000001666	ORF	Verified	YKL183W	LOT5	11	98726	99646	W	Protein of unknown function; gene expression increases in cultures shifted to a lower temperature
1373	S000001665	ORF	Verified	YKL182W	FAS1	11	100676	106831	W	Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities
1375	S000001664	ORF	Verified	YKL181W	PRS1	11	107321	108604	W	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes
1377	S000001663	ORF	Verified	YKL180W	RPL17A	11	109274	110134	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the components of the outer kinetochore DASH complex
1380	S000036150	intron	n.a.	n.a.	n.a.	11	109583	109888	W	n.a.
1381	S000001662	ORF	Verified	YKL179C	COY1	11	112508	110469	C	Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function
1383	S000001660	ORF	Dubious	YKL177W	n.a.	11	114361	114699	W	Hypothetical protein
1385	S000001661	ORF	Verified	YKL178C	STE3	11	114632	113220	C	Receptor for a factor receptor, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPCR
1387	S000001659	ORF	Verified	YKL176C	LST4	11	117991	115505	C	Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
1389	S000001658	ORF	Verified	YKL175W	ZRT3	11	118798	120309	W	Vacuolar membrane zinc transporter, transports zinc from storage in the vacuole to the cytoplasm when needed; transcription is induced under conditions of zinc deficiency
1391	S000001657	ORF	Verified	YKL174C	TPO5	11	122241	120385	C	Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles
1393	S000001656	ORF	Verified	YKL173W	SNU114	11	122522	125548	W	involved in splicing; U5 snRNP-specific protein related to EF-2
1395	S000001655	ORF	Verified	YKL172W	EBP2	11	125764	127047	W	Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles
1397	S000001654	ORF	Uncharacterized	YKL171W	n.a.	11	127480	130266	W	Hypothetical protein
1399	S000001653	ORF	Verified	YKL170W	MRPL38	11	130639	131055	W	Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels
1401	S000001652	ORF	Dubious	YKL169C	n.a.	11	131073	130690	C	Hypothetical protein
1403	S000001651	ORF	Verified	YKL168C	KKQ8	11	133497	131293	C	Putative serine/threonine protein kinase with unknown cellular role
1405	S000001650	ORF	Verified	YKL167C	MRP49	11	134139	133726	C	Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation
1407	S000001649	ORF	Verified	YKL166C	TPK3	11	135710	134514	C	Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; inhibits filamentous growth
1409	S000007617	ORF	Dubious	YKL165C-A	n.a.	11	136028	135795	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
1411	S000001648	ORF	Verified	YKL165C	MCD4	11	140696	137937	C	Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes
1413	S000006558	tRNA	n.a.	tE(UUC)K	n.a.	11	141094	141023	C	tRNA-Glu
1415	S000001647	ORF	Verified	YKL164C	PIR1	11	142824	141799	C	O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle
1417	S000001646	ORF	Verified	YKL163W	PIR3	11	144406	145383	W	O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway
1419	S000007244	ORF	Dubious	YKL162C-A	n.a.	11	146079	145927	C	Similar to PIR1, PIR2 and PIR3 proteins
1421	S000001645	ORF	Uncharacterized	YKL162C	n.a.	11	148843	147635	C	Hypothetical protein
1423	S000001644	ORF	Verified	YKL161C	n.a.	11	150692	149391	C	Mpk1-like protein kinase; associates with Rlm1p
1425	S000001643	ORF	Uncharacterized	YKL160W	ELF1	11	153274	153711	W	Protein of unknown function; deletion inhibits Brome mosaic virus expression
1427	S000001642	ORF	Verified	YKL159C	RCN1	11	154456	153821	C	Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region
1429	S000001640	ORF	Verified	YKL157W	APE2	11	154996	158186	W	Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W
1432	S000033811	intron	n.a.	n.a.	n.a.	11	155277	155659	W	n.a.
1433	S000001639	ORF	Verified	YKL156W	RPS27A	11	158619	159217	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Bp and has similarity to rat S27 ribosomal protein
1436	S000033666	intron	n.a.	n.a.	n.a.	11	158622	158971	W	n.a.
1437	S000028668	ORF	Dubious	YKL156C-A	n.a.	11	159096	158980	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
1439	S000001638	ORF	Verified	YKL155C	RSM22	11	161347	159461	C	Mitochondrial ribosomal protein of the small subunit
1441	S000001637	ORF	Verified	YKL154W	SRP102	11	161606	162340	W	Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane
1443	S000006716	tRNA	n.a.	tR(UCU)K	n.a.	11	162563	162492	C	tRNA-Arg
1446	S000001636	ORF	Dubious	YKL153W	n.a.	11	163605	164114	W	Protein required for cell viability
1448	S000001635	ORF	Verified	YKL152C	GPM1	11	164390	163647	C	Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis
1450	S000001634	ORF	Uncharacterized	YKL151C	n.a.	11	165935	164922	C	Hypothetical protein
1452	S000001633	ORF	Verified	YKL150W	MCR1	11	166549	167457	W	Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis
1454	S000001632	ORF	Verified	YKL149C	DBR1	11	168834	167617	C	RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition
1456	S000001631	ORF	Verified	YKL148C	SDH1	11	171134	169212	C	Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
1458	S000001629	ORF	Verified	YKL146W	AVT3	11	171788	173866	W	Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
1460	S000001630	ORF	Dubious	YKL147C	n.a.	11	172173	171556	C	Hypothetical protein
1462	S000001628	ORF	Verified	YKL145W	RPT1	11	174218	175621	W	One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p
1464	S000028841	ORF	Dubious	YKL145W-A	n.a.	11	174963	175055	W	Identified by expression profiling and mass spectrometry
1466	S000001627	ORF	Verified	YKL144C	RPC25	11	176486	175848	C	RNA polymerase III subunit C25
1468	S000001626	ORF	Verified	YKL143W	LTV1	11	176786	178177	W	Protein required for growth at low temperature
1470	S000001625	ORF	Verified	YKL142W	MRP8	11	178520	179179	W	Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2
1472	S000001624	ORF	Verified	YKL141W	SDH3	11	179672	180268	W	Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
1474	S000001623	ORF	Verified	YKL140W	TGL1	11	180784	182430	W	Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
1476	S000001622	ORF	Verified	YKL139W	CTK1	11	182963	184549	W	Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
1478	S000028421	ORF	Verified	YKL138C-A	HSK3	11	185017	184808	C	Component of the DASH complex which is found at kinetochores and regulates spindle assembly; in vitro DASH forms rings on microtubules and promotes microtubule stability
1480	S000001621	ORF	Verified	YKL138C	MRPL31	11	185686	185291	C	Mitochondrial ribosomal protein of the large subunit
1482	S000001620	ORF	Uncharacterized	YKL137W	n.a.	11	185988	186299	W	Hypothetical protein
1484	S000001619	ORF	Dubious	YKL136W	n.a.	11	186423	186821	W	Hypothetical protein
1486	S000001618	ORF	Verified	YKL135C	APL2	11	188647	186467	C	Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting
1488	S000001617	ORF	Verified	YKL134C	OCT1	11	191443	189131	C	Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis
1490	S000001616	ORF	Uncharacterized	YKL133C	n.a.	11	193071	191680	C	Hypothetical protein
1492	S000001614	ORF	Dubious	YKL131W	n.a.	11	194479	195000	W	Hypothetical protein
1494	S000001615	ORF	Verified	YKL132C	RMA1	11	194867	193575	C	Putative dihydrofolate synthetase; has similarity to Fol3p; similar to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase
1496	S000001613	ORF	Verified	YKL130C	SHE2	11	196029	195289	C	RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud
1498	S000001612	ORF	Verified	YKL129C	MYO3	11	200165	196350	C	One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization
1500	S000001611	ORF	Verified	YKL128C	PMU1	11	201417	200530	C	Putative phosphomutase, contains a region homologous to the active site of phsophomutases; overexpression of the gene suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant
1503	S000006626	tRNA	n.a.	tK(CUU)K	n.a.	11	202645	202717	W	tRNA-Lys
1505	S000001610	ORF	Verified	YKL127W	PGM1	11	203187	204899	W	Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism
1507	S000001609	ORF	Verified	YKL126W	YPK1	11	205353	207395	W	Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK
1509	S000001608	ORF	Verified	YKL125W	RRN3	11	207893	209776	W	Required for transcription of rDNA by RNA Polymerase I; DNA-independent RNA Polymerase I transcription factor
1511	S000001607	ORF	Verified	YKL124W	SSH4	11	210239	211978	W	Protein whose overexpression confers resistance to the growth inhibitor leflunomide; suppressor of shr3 mutation
1513	S000001606	ORF	Dubious	YKL123W	n.a.	11	211689	212069	W	Hypothetical protein
1515	S000001605	ORF	Verified	YKL122C	SRP21	11	212644	212141	C	Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm
1517	S000001604	ORF	Uncharacterized	YKL121W	n.a.	11	213788	216346	W	Hypothetical protein
1519	S000001603	ORF	Verified	YKL120W	OAC1	11	216990	217964	W	Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family
1521	S000001601	ORF	Dubious	YKL118W	n.a.	11	218772	219083	W	Involved in meiotic nuclear division.
1523	S000001602	ORF	Verified	YKL119C	VPH2	11	218863	218216	C	Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)
1526	S000006515	tRNA	n.a.	tA(AGC)K1	n.a.	11	219541	219613	W	tRNA-Ala
1528	S000001600	ORF	Verified	YKL117W	SBA1	11	219970	220620	W	Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins
1530	S000001599	ORF	Verified	YKL116C	PRR1	11	222546	220990	C	Protein kinase with a possible role in MAP kinase signaling in the pheromone response pathway
1532	S000001598	ORF	Dubious	YKL115C	n.a.	11	222931	222539	C	Hypothetical protein
1534	S000001597	ORF	Verified	YKL114C	APN1	11	224101	222998	C	Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; controls spontaneous mutations
1536	S000001596	ORF	Verified	YKL113C	RAD27	11	225521	224373	C	5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family
1538	S000001595	ORF	Verified	YKL112W	ABF1	11	226216	228411	W	DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair
1540	S000001594	ORF	Dubious	YKL111C	n.a.	11	228445	228110	C	Protein required for cell viability
1542	S000001593	ORF	Verified	YKL110C	KTI12	11	229526	228585	C	Protein associated with the RNA polymerase II Elongator complex; involved in sensitivity to G1 arrest induced by Kluyveromyces lactis toxin, zymocin
1544	S000001592	ORF	Verified	YKL109W	HAP4	11	231873	233537	W	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex
1546	S000001591	ORF	Verified	YKL108W	SLD2	11	234072	235433	W	Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate
1548	S000001590	ORF	Uncharacterized	YKL107W	n.a.	11	235787	236716	W	Hypothetical protein
1550	S000007616	ORF	Uncharacterized	YKL106C-A	n.a.	11	236912	236793	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
1552	S000001589	ORF	Verified	YKL106W	AAT1	11	237182	238537	W	Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis
1554	S000001588	ORF	Uncharacterized	YKL105C	n.a.	11	242229	238831	C	Hypothetical protein
1556	S000001587	ORF	Verified	YKL104C	GFA1	11	245019	242866	C	Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis
1558	S000001586	ORF	Verified	YKL103C	LAP4	11	247328	245784	C	Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway
1560	S000001585	ORF	Dubious	YKL102C	n.a.	11	248013	247708	C	Hypothetical protein
1562	S000001584	ORF	Verified	YKL101W	HSL1	11	248566	253122	W	Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p
1564	S000028840	ORF	Dubious	YKL100W-A	n.a.	11	253805	253894	W	Identified by expression profiling and mass spectrometry
1566	S000001583	ORF	Uncharacterized	YKL100C	n.a.	11	255106	253343	C	Hypothetical protein
1568	S000001582	ORF	Verified	YKL099C	UTP11	11	256117	255347	C	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
1570	S000001581	ORF	Uncharacterized	YKL098W	n.a.	11	256415	257488	W	Hypothetical protein
1572	S000001580	ORF	Dubious	YKL097C	n.a.	11	258558	258148	C	Hypothetical protein
1574	S000028667	ORF	Uncharacterized	YKL096C-B	n.a.	11	258867	258718	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
1576	S000001956	ORF	Verified	YKL096W-A	CWP2	11	258898	259176	W	major constituent of the cell wall containing GPI-anchor, plays a role in stabilizing the cell wall, low pH resistance protein; cell wall mannoprotein
1578	S000001579	ORF	Verified	YKL096W	CWP1	11	260777	261496	W	Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization
1580	S000001578	ORF	Verified	YKL095W	YJU2	11	261922	262758	W	Essential nuclear protein; putative spliceosomal component involved in mRNA splicing, based on computational analysis of large-scale protein-protein interaction data
1582	S000001577	ORF	Verified	YKL094W	YJU3	11	262994	263935	W	Protein of unknown function, localizes to lipid particles
1584	S000001576	ORF	Verified	YKL093W	MBR1	11	264434	265453	W	Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants
1586	S000001575	ORF	Verified	YKL092C	BUD2	11	269104	265790	C	GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types
1588	S000001574	ORF	Uncharacterized	YKL091C	n.a.	11	270295	269363	C	Sec14p homolog
1590	S000001573	ORF	Verified	YKL090W	CUE2	11	271523	272854	W	Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination
1592	S000001572	ORF	Verified	YKL089W	MIF2	11	273039	274688	W	Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p
1594	S000001571	ORF	Uncharacterized	YKL088W	n.a.	11	274928	276643	W	Protein required for cell viability
1596	S000001570	ORF	Verified	YKL087C	CYT2	11	277508	276834	C	Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1
1598	S000001569	ORF	Verified	YKL086W	SRX1	11	277926	278309	W	Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants; conserved in higher eukaryotes
1600	S000001568	ORF	Verified	YKL085W	MDH1	11	278768	279772	W	Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle
1602	S000001567	ORF	Verified	YKL084W	HOT13	11	280154	280504	W	Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small TIM (Translocase of the Inner Membrane) complexes which escort hydrophobic inner membrane proteins en route to the TIM22 complex
1604	S000001566	ORF	Dubious	YKL083W	n.a.	11	280566	281180	W	Protein required for cell viability
1606	S000001565	ORF	Uncharacterized	YKL082C	RRP14	11	281974	280670	C	Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family
1608	S000001564	ORF	Verified	YKL081W	TEF4	11	282536	284100	W	Translation elongation factor EF-1gamma
1611	S000033489	intron	n.a.	n.a.	n.a.	11	282741	283066	W	n.a.
1612	S000007301	snoRNA	n.a.	snR38	SNR38	11	282830	282924	W	Small nucleolar RNA
1614	S000001563	ORF	Verified	YKL080W	VMA5	11	284675	285853	W	Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
1616	S000001562	ORF	Verified	YKL079W	SMY1	11	286248	288218	W	Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-terminal domain is related to the motor domain of kinesins
1618	S000001561	ORF	Verified	YKL078W	DHR2	11	288490	290697	W	Predominantly nucleolar DEAH-box RNA helicase, required for 18S rRNA synthesis
1620	S000001560	ORF	Uncharacterized	YKL077W	n.a.	11	291098	292276	W	Hypothetical protein
1622	S000001559	ORF	Dubious	YKL076C	PSY1	11	292866	292483	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 69% of ORF overlaps the uncharacterized ORF YKL075C
1624	S000001558	ORF	Uncharacterized	YKL075C	n.a.	11	293953	292601	C	Hypothetical protein
1626	S000001557	ORF	Verified	YKL074C	MUD2	11	295838	294255	C	Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitment complex; interacts with Msl5p/BBP splicing factor and Sub2p; similar to metazoan splicing factor U2AF65
1628	S000001556	ORF	Verified	YKL073W	LHS1	11	296075	298720	W	Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; member of the Hsp70 family; localizes to the lumen of the ER; regulated by the unfolded protein response pathway
1630	S000001555	ORF	Verified	YKL072W	STB6	11	299227	301527	W	Protein that binds Sin3p in a two-hybrid assay
1633	S000006774	tRNA	n.a.	tW(CCA)K	n.a.	11	302563	302668	W	tRNA-Trp
1634	S000033327	intron	n.a.	n.a.	n.a.	11	302599	302632	W	n.a.
1637	S000001554	ORF	Uncharacterized	YKL071W	n.a.	11	304759	305529	W	Hypothetical protein
1639	S000001553	ORF	Uncharacterized	YKL070W	n.a.	11	305856	306365	W	Hypothetical protein
1641	S000001552	ORF	Uncharacterized	YKL069W	n.a.	11	306930	307472	W	Hypothetical protein
1643	S000006760	tRNA	n.a.	tV(AAC)K1	n.a.	11	307862	307789	C	tRNA-Val
1645	S000028524	ORF	Uncharacterized	YKL068W-A	n.a.	11	308851	309087	W	Identified by homology to <i>Ashbya gossypii</i>
1647	S000001551	ORF	Verified	YKL068W	NUP100	11	309844	312723	W	Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup116p
1649	S000006598	tRNA	n.a.	tH(GUG)K	n.a.	11	313117	313046	C	tRNA-His
1653	S000001550	ORF	Verified	YKL067W	YNK1	11	314457	314918	W	Nucleoside diphosphate kinase, catalyzes the phosphorylation of nucleoside diphosphates into the corresponding triphosphates for nucleic acid biosynthesis
1655	S000001549	ORF	Dubious	YKL066W	n.a.	11	314926	315369	W	Hypothetical protein
1657	S000001548	ORF	Uncharacterized	YKL065C	n.a.	11	316702	316082	C	Endoplasmic reticulum transmembrane protein, homolog of human BAP31 protein
1659	S000001547	ORF	Verified	YKL064W	MNR2	11	317409	320318	W	Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations
1661	S000001546	ORF	Uncharacterized	YKL063C	n.a.	11	321163	320660	C	Hypothetical protein
1663	S000001545	ORF	Verified	YKL062W	MSN4	11	322873	324765	W	Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
1665	S000001544	ORF	Uncharacterized	YKL061W	n.a.	11	325416	325757	W	Hypothetical protein
1667	S000001543	ORF	Verified	YKL060C	FBA1	11	327132	326053	C	Fructose 1,6-bisphosphate aldolase, a cytosolic enzyme required for glycolysis and gluconeogenesis; catalyzes the conversion of fructose 1,6 bisphosphate into two 3-carbon products: glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
1669	S000001542	ORF	Verified	YKL059C	MPE1	11	329088	327763	C	Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif
1671	S000001541	ORF	Verified	YKL058W	TOA2	11	329811	330179	W	Transcription factor IIA, small chain
1673	S000001540	ORF	Verified	YKL057C	NUP120	11	333614	330501	C	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for even distribution of NPCs around the nuclear envelope, involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p
1675	S000001539	ORF	Uncharacterized	YKL056C	n.a.	11	334560	334057	C	Hypothetical protein
1677	S000001538	ORF	Verified	YKL055C	OAR1	11	335802	334966	C	Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase, may comprise a type II mitochondrial fatty acid synthase along with Mct1p
1679	S000001537	ORF	Verified	YKL054C	DEF1	11	338398	336182	C	RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII
1681	S000007243	ORF	Verified	YKL053C-A	MDM35	11	339087	338827	C	Mitochondrial Distribution and Morphology; Similar to human sequence predicted by GENSCAN
1683	S000001536	ORF	Dubious	YKL053W	n.a.	11	339217	339591	W	Hypothetical protein
1685	S000001535	ORF	Verified	YKL052C	ASK1	11	340191	339313	C	Component of the DASH complex that binds to microtubules and kinetochores and is essential for chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases
1687	S000001534	ORF	Verified	YKL051W	SFK1	11	340957	342018	W	Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane
1689	S000001533	ORF	Uncharacterized	YKL050C	n.a.	11	345265	342497	C	Hypothetical protein
1691	S000001532	ORF	Verified	YKL049C	CSE4	11	346409	345720	C	Centromere protein that resembles histones, required for proper kinetochore function; homolog of human CENP-A
1693	S000001531	ORF	Verified	YKL048C	ELM1	11	348781	346859	C	Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring
1695	S000001530	ORF	Uncharacterized	YKL047W	n.a.	11	349108	350658	W	Hypothetical protein
1697	S000001529	ORF	Verified	YKL046C	DCW1	11	352269	350920	C	Mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis, homologous to Dfg5p
1699	S000001528	ORF	Verified	YKL045W	PRI2	11	353138	354724	W	Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair
1701	S000001527	ORF	Dubious	YKL044W	n.a.	11	355967	356287	W	Hypothetical protein
1703	S000001526	ORF	Verified	YKL043W	PHD1	11	356393	357493	W	Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate
1705	S000001525	ORF	Verified	YKL042W	SPC42	11	358120	359211	W	Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane
1707	S000001524	ORF	Verified	YKL041W	VPS24	11	359787	360461	W	One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); forms an ESCRT-III subcomplex with Vps2p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway
1709	S000001523	ORF	Verified	YKL040C	NFU1	11	361472	360702	C	Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria
1711	S000001522	ORF	Verified	YKL039W	PTM1	11	362266	363861	W	Protein of unknown function
1713	S000006460	snoRNA	n.a.	snR69	SNR69	11	364419	364519	W	guides 2'-O-methylation on large subunit rRNA at C2945; small nucleolar RNA snR69
1715	S000001521	ORF	Verified	YKL038W	RGT1	11	365248	368760	W	Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor
1717	S000001520	ORF	Uncharacterized	YKL037W	n.a.	11	369008	369364	W	Hypothetical protein
1719	S000001518	ORF	Verified	YKL035W	UGP1	11	369534	371033	W	UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p
1721	S000001519	ORF	Dubious	YKL036C	n.a.	11	369563	369171	C	Protein required for cell viability
1723	S000001517	ORF	Verified	YKL034W	TUL1	11	371472	373748	W	Golgi-localized RING-finger ubiquitin ligase (E3), involved in ubiquitinating and sorting membrane proteins that contain polar transmembrane domains to multivesicular bodies for delivery to the vacuole for quality control purposes
1725	S000007242	ORF	Uncharacterized	YKL033W-A	n.a.	11	374148	374858	W	Similar to S. pombe hypothetical proteins
1727	S000001516	ORF	Uncharacterized	YKL033W	n.a.	11	375099	378215	W	Protein of unknown function; localized to the cytoplasm.
1729	S000006761	tRNA	n.a.	tV(AAC)K2	n.a.	11	379323	379396	W	tRNA-Val
1731	S000001515	ORF	Verified	YKL032C	IXR1	11	381501	379708	C	Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b
1733	S000001514	ORF	Dubious	YKL031W	n.a.	11	381715	382128	W	Hypothetical protein
1735	S000001513	ORF	Dubious	YKL030W	n.a.	11	382141	382746	W	Hypothetical protein
1737	S000001512	ORF	Verified	YKL029C	MAE1	11	384368	382359	C	Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids
1739	S000001511	ORF	Verified	YKL028W	TFA1	11	385401	386849	W	TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening
1741	S000001510	ORF	Uncharacterized	YKL027W	n.a.	11	387205	388548	W	Hypothetical protein
1743	S000001509	ORF	Verified	YKL026C	GPX1	11	389526	389023	C	Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
1745	S000001508	ORF	Verified	YKL025C	PAN3	11	391922	389883	C	Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes
1747	S000001507	ORF	Verified	YKL024C	URA6	11	392783	392169	C	Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP)
1749	S000001506	ORF	Uncharacterized	YKL023W	n.a.	11	393364	394197	W	Hypothetical protein
1751	S000001505	ORF	Verified	YKL022C	CDC16	11	396891	394369	C	Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation
1753	S000001504	ORF	Verified	YKL021C	MAK11	11	398393	396987	C	Protein essential for cell growth and replication of M dsRNA virus; contains four beta-transducin repeats
1755	S000001503	ORF	Verified	YKL020C	SPT23	11	401723	398475	C	ER membrane protein involved, with its homolog Mga2p, in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
1757	S000001502	ORF	Verified	YKL019W	RAM2	11	402211	403161	W	Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor
1759	S000007615	ORF	Uncharacterized	YKL018C-A	n.a.	11	403522	403223	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
1761	S000001501	ORF	Verified	YKL018W	SWD2	11	403745	404734	W	Subunit of the COMPASS (Set1C) complex, which methylates ubiquitinated histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination
1763	S000001500	ORF	Verified	YKL017C	HCS1	11	406884	404833	C	Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities
1765	S000001499	ORF	Verified	YKL016C	ATP7	11	407632	407108	C	Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
1767	S000001498	ORF	Verified	YKL015W	PUT3	11	408187	411126	W	Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain
1769	S000001497	ORF	Verified	YKL014C	URB1	11	416556	411262	C	Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit
1771	S000001496	ORF	Verified	YKL013C	ARC19	11	417666	417151	C	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
1773	S000001495	ORF	Verified	YKL012W	PRP40	11	417953	419704	W	U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex
1775	S000001494	ORF	Verified	YKL011C	CCE1	11	420859	419798	C	cruciform cutting endonuclease
1777	S000001493	ORF	Verified	YKL010C	UFD4	11	425518	421067	C	Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins
1779	S000001492	ORF	Verified	YKL009W	MRT4	11	425885	426595	W	Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus
1781	S000001491	ORF	Verified	YKL008C	LAC1	11	428194	426938	C	Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p
1783	S000001490	ORF	Verified	YKL007W	CAP1	11	428945	429751	W	Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches
1785	S000002101	ORF	Verified	YKL006C-A	SFT1	11	430275	429841	C	Intra-Golgi v-SNARE, required for transport of proteins between an early and a later Golgi compartment
1788	S000037320	intron	n.a.	n.a.	n.a.	11	430239	430099	C	n.a.
1789	S000001489	ORF	Verified	YKL006W	RPL14A	11	431549	432363	W	N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth
1792	S000030077	intron	n.a.	n.a.	n.a.	11	431678	432075	W	n.a.
1793	S000001488	ORF	Verified	YKL005C	BYE1	11	434520	432736	C	Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit
1795	S000001487	ORF	Verified	YKL004W	AUR1	11	435223	436428	W	Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance
1797	S000001486	ORF	Verified	YKL003C	MRP17	11	437135	436740	C	Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator
1799	S000001485	ORF	Verified	YKL002W	DID4	11	437421	438187	W	Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis
1802	S000035273	intron	n.a.	n.a.	n.a.	11	437481	437548	W	n.a.
1803	S000001484	ORF	Verified	YKL001C	MET14	11	439028	438420	C	Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism
1809	S000001709	ORF	Verified	YKR001C	VPS1	11	442365	440251	C	GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization via its interaction with Sla1p; required for late Golgi-retention of some proteins including Kex2p; involved in regulating peroxisome biogenesis
1811	S000001710	ORF	Verified	YKR002W	PAP1	11	442875	444581	W	Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs
1813	S000001711	ORF	Verified	YKR003W	OSH6	11	445024	446370	W	Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery
1815	S000001712	ORF	Verified	YKR004C	ECM9	11	447679	446442	C	Non-essential protein of unknown function
1818	S000033975	intron	n.a.	n.a.	n.a.	11	447453	447350	C	n.a.
1819	S000001713	ORF	Uncharacterized	YKR005C	n.a.	11	449507	448164	C	Hypothetical protein
1821	S000001714	ORF	Verified	YKR006C	MRPL13	11	450860	450066	C	Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation
1823	S000001715	ORF	Verified	YKR007W	MEH1	11	451077	451631	W	Component of the EGO complex, which is involved in the regulation of microautophagy; localizes to the vacuolar membrane, loss results in a defect in vacuolar acidification
1825	S000001716	ORF	Verified	YKR008W	RSC4	11	451844	453721	W	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling
1827	S000001717	ORF	Verified	YKR009C	FOX2	11	456697	453995	C	Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities
1830	S000006642	tRNA	n.a.	tL(CAA)K	n.a.	11	458200	458313	W	tRNA-Leu
1831	S000033792	intron	n.a.	n.a.	n.a.	11	458238	458269	W	n.a.
1834	S000001718	ORF	Verified	YKR010C	TOF2	11	460882	458567	C	Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1
1836	S000001719	ORF	Uncharacterized	YKR011C	n.a.	11	462339	461278	C	Hypothetical protein
1838	S000001721	ORF	Verified	YKR013W	PRY2	11	463602	464591	W	Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins
1840	S000001720	ORF	Dubious	YKR012C	n.a.	11	463759	463382	C	Hypothetical protein
1842	S000001722	ORF	Verified	YKR014C	YPT52	11	465714	465010	C	GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis
1844	S000001723	ORF	Uncharacterized	YKR015C	n.a.	11	468310	466604	C	Hypothetical protein
1846	S000001724	ORF	Uncharacterized	YKR016W	n.a.	11	469360	470982	W	The authentic, non-tagged protein was localized to the mitochondria
1848	S000001725	ORF	Uncharacterized	YKR017C	n.a.	11	472992	471337	C	Hypothetical protein
1850	S000001726	ORF	Uncharacterized	YKR018C	n.a.	11	475543	473366	C	Hypothetical protein
1852	S000001727	ORF	Verified	YKR019C	IRS4	11	477706	475859	C	Protein involved in regulation of phosphatidylinositol 4,5-bisphosphate concentrations; Irs4p and Tax4p bind and activate the phosphatase Inp51p; mutation confers an increase in rDNA silencing
1854	S000001728	ORF	Verified	YKR020W	VPS51	11	477981	478475	W	Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP)  complex to the SNARE Tlg1p
1856	S000001729	ORF	Uncharacterized	YKR021W	n.a.	11	478877	481624	W	Hypothetical protein
1858	S000001730	ORF	Uncharacterized	YKR022C	n.a.	11	482782	481814	C	Protein required for cell viability
1860	S000001731	ORF	Uncharacterized	YKR023W	n.a.	11	483062	484654	W	Hypothetical protein
1862	S000001732	ORF	Verified	YKR024C	DBP7	11	487015	484787	C	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
1864	S000001733	ORF	Verified	YKR025W	RPC37	11	487413	488261	W	RNA polymerase III subunit C37
1866	S000001734	ORF	Verified	YKR026C	GCN3	11	489298	488381	C	Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression
1870	S000006703	tRNA	n.a.	tR(ACG)K	n.a.	11	490611	490683	W	tRNA-Arg
1872	S000001735	ORF	Uncharacterized	YKR027W	n.a.	11	491007	493304	W	The authentic, non-tagged protein was localized to the mitochondria
1874	S000001736	ORF	Verified	YKR028W	SAP190	11	493900	497196	W	Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p
1876	S000001737	ORF	Verified	YKR029C	SET3	11	499475	497220	C	Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains
1878	S000001738	ORF	Verified	YKR030W	GMH1	11	499924	500745	W	Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting
1880	S000001739	ORF	Verified	YKR031C	SPO14	11	506037	500986	C	Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis
1882	S000001740	ORF	Dubious	YKR032W	n.a.	11	506159	506473	W	Hypothetical protein
1884	S000001742	ORF	Verified	YKR034W	DAL80	11	506540	507349	W	Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p
1886	S000001741	ORF	Dubious	YKR033C	n.a.	11	506946	506521	C	Hypothetical protein
1888	S000006435	ORF	Verified	YKR035W-A	DID2	11	507581	508195	W	Class E protein of the vacuolar protein-sorting (Vps) pathway, associates reversibly with the late endosome, has human ortholog that may be altered in breast tumors
1890	S000001743	ORF	Dubious	YKR035C	n.a.	11	508203	507562	C	Hypothetical protein
1892	S000001744	ORF	Verified	YKR036C	CAF4	11	510323	508344	C	WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p
1894	S000001745	ORF	Verified	YKR037C	SPC34	11	511439	510552	C	Component of Dam1p complex, important for spindle and kinetochore integrity; localized to nuclear side of spindle pole body and along mitotic spindle
1896	S000001746	ORF	Verified	YKR038C	KAE1	11	512801	511641	C	Putative glycoprotease that interacts with Bud32p, which is a member of the novel protein kinase piD261 family
1898	S000006540	tRNA	n.a.	tD(GUC)K	n.a.	11	513045	512974	C	tRNA-Asp
1901	S000001747	ORF	Verified	YKR039W	GAP1	11	514705	516513	W	General amino acid permease; localization to the plasma membrane is regulated by nitrogen source
1904	S000006516	tRNA	n.a.	tA(AGC)K2	n.a.	11	517630	517702	W	tRNA-Ala
1906	S000001749	ORF	Uncharacterized	YKR041W	n.a.	11	517840	518592	W	Hypothetical protein
1908	S000001748	ORF	Dubious	YKR040C	n.a.	11	518208	517705	C	Hypothetical protein
1910	S000001750	ORF	Verified	YKR042W	UTH1	11	518914	520266	W	Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death
1912	S000001751	ORF	Uncharacterized	YKR043C	n.a.	11	521354	520539	C	Hypothetical protein
1914	S000001752	ORF	Verified	YKR044W	UIP5	11	521657	522988	W	Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates
1916	S000001753	ORF	Uncharacterized	YKR045C	n.a.	11	523611	523060	C	Hypothetical protein
1918	S000001754	ORF	Uncharacterized	YKR046C	PET10	11	524716	523865	C	Protein of unknown function that co-purifies with lipid particles; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange
1920	S000001755	ORF	Dubious	YKR047W	n.a.	11	524899	525204	W	Hypothetical protein
1922	S000001756	ORF	Verified	YKR048C	NAP1	11	526282	525029	C	Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus
1924	S000001757	ORF	Uncharacterized	YKR049C	n.a.	11	526873	526472	C	The authentic, non-tagged protein was localized to the mitochondria
1926	S000001758	ORF	Verified	YKR050W	TRK2	11	527457	530126	W	Component of the Trk1p-Trk2p potassium transport system
1928	S000001759	ORF	Uncharacterized	YKR051W	n.a.	11	530588	531844	W	Hypothetical protein
1930	S000001760	ORF	Verified	YKR052C	MRS4	11	533106	532192	C	Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs3p; functions under low-iron conditions; may transport other cations in addition to iron
1932	S000001761	ORF	Verified	YKR053C	YSR3	11	534923	533709	C	Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p
1934	S000001762	ORF	Verified	YKR054C	DYN1	11	547567	535289	C	Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p
1936	S000001763	ORF	Verified	YKR055W	RHO4	11	547858	548733	W	Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity
1938	S000001764	ORF	Verified	YKR056W	TRM2	11	549090	551009	W	tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; previously thought to be an endo-exonuclease
1940	S000001765	ORF	Verified	YKR057W	RPS21A	11	551299	551884	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein
1943	S000036540	intron	n.a.	n.a.	n.a.	11	551323	551644	W	n.a.
1944	S000001766	ORF	Verified	YKR058W	GLG1	11	552820	554262	W	Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin
1946	S000001767	ORF	Verified	YKR059W	TIF1	11	554629	555816	W	Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
1948	S000001768	ORF	Uncharacterized	YKR060W	UTP30	11	556160	556984	W	Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
1950	S000001769	ORF	Verified	YKR061W	KTR2	11	557319	558596	W	Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
1952	S000006502	snoRNA	n.a.	snR42	SNR42	11	559008	558658	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2971
1954	S000001770	ORF	Verified	YKR062W	TFA2	11	559308	560294	W	TFIIE small subunit, involved in RNA polymerase II transcription initiation
1956	S000001771	ORF	Verified	YKR063C	LAS1	11	561939	560431	C	Essential nuclear protein possibly involved in bud formation and morphogenesis; mutants require the SSD1-v allele for viability
1958	S000001772	ORF	Uncharacterized	YKR064W	n.a.	11	562189	564780	W	Hypothetical protein
1960	S000001773	ORF	Uncharacterized	YKR065C	n.a.	11	565534	564941	C	The authentic, non-tagged protein was localized to the mitochondria
1962	S000001774	ORF	Verified	YKR066C	CCP1	11	566840	565755	C	Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress
1964	S000001775	ORF	Verified	YKR067W	GPT2	11	567560	569791	W	Glycerol-3-phosphate acyltransferase located in both lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone, which are intermediate steps in lipid biosynthesis
1966	S000001776	ORF	Verified	YKR068C	BET3	11	570551	569970	C	Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex
1968	S000001777	ORF	Verified	YKR069W	MET1	11	571254	573035	W	S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in sulfate assimilation, methionine metabolism, and siroheme biosynthesis
1970	S000001778	ORF	Uncharacterized	YKR070W	n.a.	11	573216	574274	W	Hypothetical protein
1972	S000001779	ORF	Verified	YKR071C	DRE2	11	575622	574576	C	Protein of unknown function; mutation displays synthetic lethal interaction with the pol3-13 allele of CDC2
1974	S000001780	ORF	Verified	YKR072C	SIS2	11	577765	576077	C	Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion homeostasis and cell cycle progression
1976	S000001781	ORF	Dubious	YKR073C	n.a.	11	578149	577829	C	Hypothetical protein
1978	S000006632	tRNA	n.a.	tK(UUU)K	n.a.	11	578607	578702	W	tRNA-Lys
1979	S000034204	intron	n.a.	n.a.	n.a.	11	578644	578666	W	n.a.
1982	S000001782	ORF	Uncharacterized	YKR074W	n.a.	11	578851	579318	W	Hypothetical protein
1984	S000028669	ORF	Dubious	YKR075W-A	n.a.	11	579854	580123	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
1986	S000001783	ORF	Uncharacterized	YKR075C	n.a.	11	580392	579469	C	Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p
1988	S000001784	ORF	Verified	YKR076W	ECM4	11	581925	583037	W	Non-essential protein of unknown function; similar to Ygr154cp
1990	S000001785	ORF	Uncharacterized	YKR077W	n.a.	11	583295	584386	W	Hypothetical protein
1992	S000001786	ORF	Uncharacterized	YKR078W	n.a.	11	584594	586351	W	Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate
1994	S000001787	ORF	Uncharacterized	YKR079C	TRZ1	11	588947	586431	C	tRNase Z, involved in RNA processing, has two putative nucleotide triphosphate-binding motifs (P-loop) and a conserved histidine motif, homolog of the human candidate prostate cancer susceptibility gene ELAC2
1996	S000001788	ORF	Verified	YKR080W	MTD1	11	590037	590999	W	NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline
1998	S000001789	ORF	Verified	YKR081C	RPF2	11	592182	591148	C	Essential protein involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles
2000	S000001790	ORF	Verified	YKR082W	NUP133	11	592467	595940	W	Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p
2002	S000001791	ORF	Verified	YKR083C	DAD2	11	596464	596063	C	Essential protein, component of the DASH complex; involved in spindle integrity and kinetochore function; interacts with Duo1p and Dam1p; localizes to intranuclear spindles and kinetochore
2004	S000001792	ORF	Verified	YKR084C	HBS1	11	598532	596697	C	GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha and Sup35p; associates with Dom34p, and shares a similar genetic relationship with genes that encode ribosomal protein components
2006	S000001793	ORF	Verified	YKR085C	MRPL20	11	599323	598736	C	Mitochondrial ribosomal protein of the large subunit
2008	S000001794	ORF	Verified	YKR086W	PRP16	11	599499	602714	W	RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-dependent RNA unwinding activity
2010	S000001795	ORF	Verified	YKR087C	OMA1	11	603874	602837	C	Metalloendopeptidase of the mitochondrial inner membrane, involved in turnover of membrane-embedded proteins; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes
2012	S000001796	ORF	Uncharacterized	YKR088C	n.a.	11	605060	604047	C	Integral membrane protein localized to vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
2014	S000001797	ORF	Uncharacterized	YKR089C	n.a.	11	608007	605275	C	Protein of unknown function found in lipid particles; potential Cdc28p substrate
2016	S000001798	ORF	Verified	YKR090W	PXL1	11	608588	610708	W	LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin
2018	S000001799	ORF	Verified	YKR091W	SRL3	11	611167	611907	W	Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate
2020	S000001800	ORF	Verified	YKR092C	SRP40	11	613527	612307	C	Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140
2022	S000001801	ORF	Verified	YKR093W	PTR2	11	615372	617177	W	Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p
2024	S000001802	ORF	Verified	YKR094C	RPL40B	11	618392	617638	C	Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
2027	S000034524	intron	n.a.	n.a.	n.a.	11	618384	618017	C	n.a.
2028	S000001803	ORF	Verified	YKR095W	MLP1	11	619447	625074	W	Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length; involved in the retention of unspliced mRNAs in the nucleus
2030	S000028512	ORF	Uncharacterized	YKR095W-A	n.a.	11	625506	625847	W	Protein of unknown function, conserved in Ashbya gossypii
2033	S000030273	intron	n.a.	n.a.	n.a.	11	625544	625618	W	n.a.
2034	S000001804	ORF	Uncharacterized	YKR096W	n.a.	11	626435	630022	W	Hypothetical protein
2036	S000001805	ORF	Verified	YKR097W	PCK1	11	630790	632439	W	Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol
2038	S000001806	ORF	Verified	YKR098C	UBP11	11	634817	632664	C	Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins
2040	S000001807	ORF	Verified	YKR099W	BAS1	11	635489	637924	W	Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways
2042	S000001808	ORF	Uncharacterized	YKR100C	SKG1	11	639606	638539	C	Transmembrane protein of unknown function; localizes on the inner surface of the plasma membrane at the bud and in the daughter cell; affects the cell wall polymer composition
2044	S000001809	ORF	Verified	YKR101W	SIR1	11	640106	642142	W	Protein involved in repression of transcription at the silent mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin
2046	S000001810	ORF	Verified	YKR102W	FLO10	11	645994	649503	W	Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation
2048	S000001811	ORF	Verified	YKR103W	NFT1	11	652718	656374	W	Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds.
2050	S000001812	ORF	Verified	YKR104W	n.a.	11	656474	657394	W	ORFs YKR103W and YKR104W are merged in different strain backgrounds
2052	S000001813	ORF	Uncharacterized	YKR105C	n.a.	11	660102	658354	C	Hypothetical protein
2054	S000001814	ORF	Uncharacterized	YKR106W	n.a.	11	661080	662927	W	Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YCL073C
2065	S000028673	ORF	Dubious	YLL067W-A	n.a.	12	843	1325	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2067	S000003990	ORF	Uncharacterized	YLL067C	n.a.	12	4301	585	C	Hypothetical protein
2070	S000034998	intron	n.a.	n.a.	n.a.	12	4014	3916	C	n.a.
2071	S000028672	ORF	Uncharacterized	YLL066W-B	n.a.	12	5605	5775	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2077	S000028671	ORF	Dubious	YLL066W-A	n.a.	12	6486	6968	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2079	S000003989	ORF	Uncharacterized	YLL066C	n.a.	12	9836	6120	C	Hypothetical protein
2082	S000034883	intron	n.a.	n.a.	n.a.	12	9549	9451	C	n.a.
2088	S000003988	ORF	Dubious	YLL065W	n.a.	12	11726	12076	W	growth inhibitor
2093	S000003987	ORF	Uncharacterized	YLL064C	n.a.	12	13445	13083	C	Hypothetical protein
2095	S000003986	ORF	Verified	YLL063C	AYT1	12	16072	14648	C	Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis
2097	S000003985	ORF	Verified	YLL062C	MHT1	12	17613	16639	C	S-methylmethionine-homocysteine methyltransferase, functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio
2099	S000003984	ORF	Verified	YLL061W	MMP1	12	17956	19707	W	High-affinity S-methylmethionine permease, required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p
2101	S000003983	ORF	Verified	YLL060C	GTT2	12	21839	21138	C	Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p
2103	S000003982	ORF	Dubious	YLL059C	n.a.	12	22980	22474	C	Hypothetical protein
2105	S000003981	ORF	Uncharacterized	YLL058W	n.a.	12	23569	25296	W	Hypothetical protein
2107	S000003980	ORF	Uncharacterized	YLL057C	JLP1	12	26994	25756	C	Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use as a sulfur source, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)
2109	S000003979	ORF	Uncharacterized	YLL056C	n.a.	12	28305	27409	C	Protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
2111	S000003978	ORF	Uncharacterized	YLL055W	n.a.	12	30109	31704	W	Hypothetical protein
2113	S000003977	ORF	Uncharacterized	YLL054C	n.a.	12	35203	32894	C	Hypothetical protein
2115	S000003976	ORF	Uncharacterized	YLL053C	n.a.	12	35960	35502	C	Hypothetical protein; maybe continuous with YLL052C (AQY2) in some strain backgrounds including Sigma1278b; functions as an aquaporin in these strains.
2117	S000003975	ORF	Verified	YLL052C	AQY2	12	36360	35911	C	Water channel that mediates the transport of water across cell membranes and may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains
2119	S000003974	ORF	Verified	YLL051C	FRE6	12	39470	37332	C	Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels
2121	S000003973	ORF	Verified	YLL050C	COF1	12	40413	39803	C	Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments , thought to be regulated by phosphorylation at SER4, ubiquitous and essential in eukaryotes
2124	S000037512	intron	n.a.	n.a.	n.a.	12	40399	40221	C	n.a.
2125	S000003972	ORF	Uncharacterized	YLL049W	n.a.	12	40665	41204	W	Hypothetical protein
2127	S000003971	ORF	Verified	YLL048C	YBT1	12	46264	41279	C	Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters
2129	S000003970	ORF	Dubious	YLL047W	n.a.	12	46671	47054	W	Hypothetical protein
2131	S000003969	ORF	Verified	YLL046C	RNP1	12	47462	46713	C	Ribonucleoprotein that contains two RNA recognition motifs (RRM)
2133	S000003967	ORF	Dubious	YLL044W	n.a.	12	48215	48661	W	Hypothetical protein
2135	S000003968	ORF	Verified	YLL045C	RPL8B	12	48628	47858	C	Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
2137	S000003966	ORF	Verified	YLL043W	FPS1	12	49937	51946	W	Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) family of channel proteins; involved in efflux of glycerol and in uptake of the trivalent metalloids arsenite and antimonite
2139	S000003965	ORF	Verified	YLL042C	ATG10	12	52589	52086	C	Enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy
2141	S000003964	ORF	Verified	YLL041C	SDH2	12	53930	53130	C	Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
2143	S000003963	ORF	Verified	YLL040C	VPS13	12	63644	54210	C	Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention
2145	S000003962	ORF	Verified	YLL039C	UBI4	12	65206	64061	C	Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response
2147	S000003961	ORF	Verified	YLL038C	ENT4	12	66517	65774	C	Protein of unknown function, contains an N-terminal epsin-like domain
2149	S000003960	ORF	Dubious	YLL037W	n.a.	12	66561	66941	W	Protein required for cell viability
2151	S000003959	ORF	Verified	YLL036C	PRP19	12	68255	66744	C	Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases
2153	S000003958	ORF	Verified	YLL035W	GRC3	12	68579	70477	W	Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated
2155	S000003957	ORF	Verified	YLL034C	RIX7	12	73145	70632	C	Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions
2157	S000003956	ORF	Uncharacterized	YLL033W	n.a.	12	73408	74100	W	ORF, Uncharacterized
2159	S000003955	ORF	Uncharacterized	YLL032C	n.a.	12	76746	74269	C	Hypothetical protein
2161	S000003954	ORF	Verified	YLL031C	GPI13	12	80204	77151	C	ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein
2163	S000003953	ORF	Dubious	YLL030C	n.a.	12	80696	80355	C	Hypothetical protein
2165	S000003952	ORF	Uncharacterized	YLL029W	n.a.	12	81460	83709	W	Hypothetical protein
2167	S000003951	ORF	Verified	YLL028W	TPO1	12	84803	86563	W	Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane
2169	S000003950	ORF	Verified	YLL027W	ISA1	12	87402	88154	W	Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources
2171	S000003949	ORF	Verified	YLL026W	HSP104	12	88622	91348	W	Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation
2174	S000006683	tRNA	n.a.	tP(UGG)L	n.a.	12	92547	92649	W	tRNA-Pro
2175	S000036013	intron	n.a.	n.a.	n.a.	12	92583	92613	W	n.a.
2178	S000003948	ORF	Uncharacterized	YLL025W	n.a.	12	94746	95120	W	Hypothetical protein
2180	S000003947	ORF	Verified	YLL024C	SSA2	12	97484	95565	C	ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall
2182	S000003946	ORF	Uncharacterized	YLL023C	n.a.	12	98835	97996	C	Hypothetical protein
2184	S000003945	ORF	Verified	YLL022C	HIF1	12	100200	99043	C	Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing
2186	S000003944	ORF	Verified	YLL021W	SPA2	12	100946	105346	W	Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate
2188	S000003943	ORF	Dubious	YLL020C	n.a.	12	105860	105555	C	Hypothetical protein
2190	S000028670	ORF	Dubious	YLL019W-A	n.a.	12	106907	106999	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2192	S000003942	ORF	Verified	YLL019C	KNS1	12	107898	105685	C	Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues
2194	S000007245	ORF	Verified	YLL018C-A	COX19	12	108971	108675	C	Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase
2196	S000003941	ORF	Verified	YLL018C	DPS1	12	111574	109901	C	Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation
2202	S000003938	ORF	Verified	YLL015W	BPT1	12	116431	121110	W	ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p
2204	S000003937	ORF	Uncharacterized	YLL014W	n.a.	12	121321	121647	W	Hypothetical protein
2206	S000003936	ORF	Verified	YLL013C	PUF3	12	124713	122074	C	Protein that regulates degradation of specific mRNAs such as COX17, binds almost exclusively to cytoplasmic mRNAs encoding mitochondrial proteins, member of the PUF protein family that contains Pumilio homology domains
2208	S000003935	ORF	Verified	YLL012W	YEH1	12	125533	127254	W	Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes
2210	S000003934	ORF	Verified	YLL011W	SOF1	12	127522	128991	W	Essential subunit of the U3 (box C+D) snRNP complex required for 2' O-methylation of pre-RNA; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p
2212	S000003933	ORF	Verified	YLL010C	PSR1	12	130612	129329	C	Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p
2214	S000003932	ORF	Verified	YLL009C	COX17	12	131413	131204	C	Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase
2216	S000003931	ORF	Verified	YLL008W	DRS1	12	131728	133986	W	Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles
2218	S000003930	ORF	Uncharacterized	YLL007C	n.a.	12	136298	134301	C	Hypothetical protein
2220	S000028560	ORF	Uncharacterized	YLL006W-A	n.a.	12	136344	136520	W	Identified by fungal homology and RT-PCR
2222	S000003929	ORF	Verified	YLL006W	MMM1	12	136585	137865	W	Mitochondrial outer membrane protein required for normal mitochondrial morphology and mtDNA stability; involved in tethering mitochondria to the actin cytoskeleton and in anchoring mtDNA nucleoids
2224	S000003928	ORF	Verified	YLL005C	SPO75	12	140545	137939	C	Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis
2226	S000003927	ORF	Verified	YLL004W	ORC3	12	141072	142922	W	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
2228	S000003926	ORF	Verified	YLL003W	SFI1	12	143200	146040	W	Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C
2230	S000003925	ORF	Verified	YLL002W	RTT109	12	146290	147600	W	Protein with a role in regulation of Ty1 transposition
2232	S000003924	ORF	Verified	YLL001W	DNM1	12	147889	150162	W	Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis
2238	S000003991	ORF	Uncharacterized	YLR001C	n.a.	12	153976	151388	C	Hypothetical protein
2240	S000003992	ORF	Verified	YLR002C	NOC3	12	156333	154342	C	Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport; also binds to chromatin to promote the association of DNA replication factors and replication initiation
2242	S000003993	ORF	Uncharacterized	YLR003C	n.a.	12	157729	156854	C	Hypothetical protein
2244	S000003994	ORF	Uncharacterized	YLR004C	n.a.	12	159504	157933	C	Hypothetical protein
2246	S000003995	ORF	Verified	YLR005W	SSL1	12	160048	161433	W	Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p
2248	S000003996	ORF	Verified	YLR006C	SSK1	12	163892	161754	C	Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate
2250	S000003997	ORF	Verified	YLR007W	NSE1	12	164391	165401	W	Essential nuclear protein required for DNA repair; forms a complex with Smc5p and Smc6p
2252	S000003998	ORF	Verified	YLR008C	PAM18	12	166082	165576	C	Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam16p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain
2254	S000003999	ORF	Verified	YLR009W	RLP24	12	166536	167135	W	Ribosomal Like Protein 24
2256	S000004000	ORF	Verified	YLR010C	TEN1	12	167801	167319	C	protein involved in Telomeric pathways in association with Stn1; Protein required for cell viability
2258	S000006728	tRNA	n.a.	tS(AGA)L	n.a.	12	168024	167943	C	tRNA-Ser
2261	S000004001	ORF	Verified	YLR011W	LOT6	12	169102	169677	W	Putative NADPH-dependent FMN reductase with strong ferricyanide reductase activity in vitro; gene expression increases in cultures shifted to a lower temperature
2263	S000004002	ORF	Uncharacterized	YLR012C	n.a.	12	170280	169981	C	Hypothetical protein
2265	S000004003	ORF	Verified	YLR013W	GAT3	12	171338	171763	W	Protein containing GATA family zinc finger motifs
2267	S000004004	ORF	Verified	YLR014C	PPR1	12	174981	172267	C	Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p
2269	S000004005	ORF	Verified	YLR015W	BRE2	12	175226	176743	W	Subunit of the COMPASS (Set1C) complex, which methylates Rad6p ubiquitinated histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to the trithorax-group protein ASH2L
2271	S000004006	ORF	Uncharacterized	YLR016C	n.a.	12	177415	176801	C	Hypothetical protein
2273	S000004007	ORF	Verified	YLR017W	MEU1	12	177607	178620	W	Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression
2275	S000004008	ORF	Verified	YLR018C	POM34	12	179605	178706	C	Integral membrane protein of the nuclear pore complex, localizes adjacent to the nuclear membrane
2277	S000004009	ORF	Verified	YLR019W	PSR2	12	180287	181480	W	Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p
2279	S000004010	ORF	Verified	YLR020C	YEH2	12	183404	181788	C	Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism
2281	S000004011	ORF	Uncharacterized	YLR021W	n.a.	12	183622	184161	W	Hypothetical protein
2283	S000004012	ORF	Uncharacterized	YLR022C	n.a.	12	184925	184173	C	Essential protein involved in RNA metabolism, one of two yeast homologs (with Yhr087wp) of the human protein SBDS responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome, also conserved in Archaea
2285	S000004013	ORF	Verified	YLR023C	IZH3	12	187128	185497	C	Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity
2287	S000004014	ORF	Verified	YLR024C	UBR2	12	193282	187664	C	Cytoplasmic ubiquitin-protein ligase (E3)
2289	S000004015	ORF	Verified	YLR025W	SNF7	12	194453	195175	W	One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes
2291	S000004016	ORF	Verified	YLR026C	SED5	12	196473	195451	C	cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins
2293	S000004017	ORF	Verified	YLR027C	AAT2	12	198086	196830	C	Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells
2295	S000007497	snoRNA	n.a.	snR30	SNR30	12	198785	199385	W	H/ACA small nucleolar RNA (snoRNA); required for cleavage of 35S pre-rRNA at sites A1 and A2 to form mature 18S rRNA
2297	S000004018	ORF	Verified	YLR028C	ADE16	12	201316	199541	C	Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine
2299	S000004019	ORF	Verified	YLR029C	RPL15A	12	202591	201977	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
2301	S000004020	ORF	Uncharacterized	YLR030W	n.a.	12	203291	204082	W	Hypothetical protein
2303	S000004021	ORF	Uncharacterized	YLR031W	n.a.	12	204226	204786	W	Hypothetical protein
2305	S000004022	ORF	Verified	YLR032W	RAD5	12	204992	208501	W	Single-stranded DNA-dependent ATPase, involved in postreplication repair; contains RING finger domain
2307	S000004023	ORF	Verified	YLR033W	RSC58	12	208762	210270	W	Remodels the structure of chromatin complex 58KDa subunit; Chromatin Remodeling Complex subunit
2309	S000004024	ORF	Verified	YLR034C	SMF3	12	211934	210513	C	Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins
2311	S000004025	ORF	Verified	YLR035C	MLH2	12	214457	212370	C	Protein required for DNA mismatch repair in mitosis and meiosis; involved in the repair of mutational intermediates; forms a complex with Pms1p and Msh1p to repair mismatched DNA
2313	S000006524	tRNA	n.a.	tA(UGC)L	n.a.	12	214956	214884	C	tRNA-Ala
2320	S000004026	ORF	Uncharacterized	YLR036C	n.a.	12	222133	221522	C	Hypothetical protein
2322	S000004027	ORF	Verified	YLR037C	DAN2	12	223060	222686	C	Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
2324	S000004028	ORF	Verified	YLR038C	COX12	12	225173	224922	C	Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of fully active cytochrome c oxidase but not required for activity after assembly
2326	S000004029	ORF	Verified	YLR039C	RIC1	12	228597	225427	C	Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes
2328	S000004031	ORF	Dubious	YLR041W	n.a.	12	229378	229698	W	Hypothetical protein
2330	S000004030	ORF	Uncharacterized	YLR040C	n.a.	12	229583	228909	C	Hypothetical protein
2332	S000004032	ORF	Uncharacterized	YLR042C	n.a.	12	230452	229967	C	Hypothetical protein
2334	S000004033	ORF	Verified	YLR043C	TRX1	12	232014	231703	C	Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against both oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance
2336	S000004034	ORF	Verified	YLR044C	PDC1	12	234082	232391	C	Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism
2338	S000004035	ORF	Verified	YLR045C	STU2	12	237704	235038	C	Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p
2340	S000004036	ORF	Uncharacterized	YLR046C	n.a.	12	238814	238002	C	Putative membrane protein, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
2342	S000004037	ORF	Uncharacterized	YLR047C	n.a.	12	241408	239348	C	Hypothetical protein
2344	S000004038	ORF	Verified	YLR048W	RPS0B	12	242233	243350	W	Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
2347	S000032919	intron	n.a.	n.a.	n.a.	12	242323	242681	W	n.a.
2348	S000004039	ORF	Uncharacterized	YLR049C	n.a.	12	245173	243887	C	Hypothetical protein
2350	S000004040	ORF	Uncharacterized	YLR050C	n.a.	12	246073	245588	C	Hypothetical protein
2352	S000004041	ORF	Uncharacterized	YLR051C	n.a.	12	246978	246325	C	Protein required for cell viability
2354	S000004042	ORF	Verified	YLR052W	IES3	12	247202	247954	W	Subunit of the INO80 chromatin remodeling complex
2356	S000004043	ORF	Uncharacterized	YLR053C	n.a.	12	248427	248101	C	Hypothetical protein
2358	S000004044	ORF	Uncharacterized	YLR054C	OSW2	12	250979	248718	C	Protein of unknown function proposed to be involved in the assembly of the spore wall
2361	S000035046	intron	n.a.	n.a.	n.a.	12	250948	250862	C	n.a.
2362	S000004045	ORF	Verified	YLR055C	SPT8	12	253081	251273	C	Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters
2364	S000004046	ORF	Verified	YLR056W	ERG3	12	253862	254959	W	C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources
2366	S000004047	ORF	Uncharacterized	YLR057W	n.a.	12	255307	257856	W	Hypothetical protein
2368	S000004048	ORF	Verified	YLR058C	SHM2	12	259402	257993	C	serine hydroxymethyltransferase
2370	S000004049	ORF	Verified	YLR059C	REX2	12	260548	259739	C	RNA exonuclease, required for U4 snRNA maturation; functions redundantly with Rnh70p in 5.8S rRNA maturation, and with Rnh70p and Rex3p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases
2372	S000004050	ORF	Verified	YLR060W	FRS1	12	260980	262767	W	Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate the active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
2374	S000004051	ORF	Verified	YLR061W	RPL22A	12	263195	263949	W	Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein
2377	S000030140	intron	n.a.	n.a.	n.a.	12	263207	263595	W	n.a.
2378	S000004052	ORF	Dubious	YLR062C	BUD28	12	263955	263578	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene RPL22A; diploid mutant displays a weak budding pattern phenotype in a systematic assay
2380	S000004053	ORF	Uncharacterized	YLR063W	n.a.	12	264158	265255	W	Hypothetical protein
2382	S000004054	ORF	Uncharacterized	YLR064W	n.a.	12	265457	266278	W	Hypothetical protein
2384	S000004055	ORF	Uncharacterized	YLR065C	n.a.	12	266919	266374	C	Hypothetical protein
2386	S000004056	ORF	Verified	YLR066W	SPC3	12	267170	267724	W	Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23
2388	S000004057	ORF	Verified	YLR067C	PET309	12	270711	267814	C	Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; located in the mitochondrial inner membrane
2390	S000004058	ORF	Verified	YLR068W	FYV7	12	271009	271464	W	Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in processing the 35S rRNA primary transcript to generate the 20S and 27SA2 pre-rRNA transcripts
2392	S000004059	ORF	Verified	YLR069C	MEF1	12	273916	271631	C	Mitochondrial elongation factor involved in translational elongation
2394	S000004060	ORF	Verified	YLR070C	XYL2	12	275212	274142	C	Xylitol dehydrogenase, converts xylitol to D-xylulose in the endogenous xylose utilization pathway
2396	S000004061	ORF	Verified	YLR071C	RGR1	12	278627	275379	C	Component of RNA polymerase II holoenzyme/mediator complex; affects chromatin structure and transcriptional regulation of diverse genes; required for glucose repression, HO repression, RME1 repression and sporulation
2398	S000004062	ORF	Uncharacterized	YLR072W	n.a.	12	278863	280944	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
2400	S000004063	ORF	Uncharacterized	YLR073C	n.a.	12	281622	281020	C	Hypothetical protein
2402	S000004064	ORF	Verified	YLR074C	BUD20	12	282457	281957	C	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
2404	S000004065	ORF	Verified	YLR075W	RPL10	12	282928	283593	W	Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family
2406	S000004066	ORF	Dubious	YLR076C	n.a.	12	283608	283186	C	Protein required for cell viability
2408	S000004067	ORF	Uncharacterized	YLR077W	n.a.	12	283873	285624	W	The authentic, non-tagged protein was localized to the mitochondria
2410	S000004068	ORF	Verified	YLR078C	BOS1	12	286560	285737	C	v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi
2413	S000036711	intron	n.a.	n.a.	n.a.	12	286557	286469	C	n.a.
2414	S000004069	ORF	Verified	YLR079W	SIC1	12	286821	287675	W	Inhibitor of Cdc28-Clb kinase complexes that controls the G1/S phase transition, preventing premature S phase entry and ensuring genomic integrity; multisite phosphorylation by Cdc28-Cln kinase targets Sic1p for SCF(CDC4)-dependent turnover
2416	S000004070	ORF	Verified	YLR080W	EMP46	12	287917	289251	W	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport
2418	S000004071	ORF	Verified	YLR081W	GAL2	12	290213	291937	W	Galactose permease, required for utilization of galactose; also able to transport glucose
2420	S000004072	ORF	Verified	YLR082C	SRL2	12	293573	292395	C	Protein of unknown function; overexpression suppresses the lethality caused by a rad53 null mutation
2422	S000004073	ORF	Verified	YLR083C	EMP70	12	296095	294092	C	Protein whose 24kDa cleavage product is found in endosome-enriched membrane fractions, predicted to be a transmembrane protein
2424	S000004074	ORF	Verified	YLR084C	RAX2	12	300252	296590	C	N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p
2426	S000004075	ORF	Verified	YLR085C	ARP6	12	301990	300674	C	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
2428	S000004076	ORF	Verified	YLR086W	SMC4	12	302244	306500	W	Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate
2430	S000004077	ORF	Verified	YLR087C	CSF1	12	315732	306856	C	Protein required for fermentation at low temperature
2432	S000004078	ORF	Verified	YLR088W	GAA1	12	316108	317952	W	Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anchoring signal and attaches GPI to proteins in the ER
2434	S000004079	ORF	Uncharacterized	YLR089C	n.a.	12	320016	318238	C	Putative alanine transaminase (glutamic pyruvic transaminase)
2436	S000004080	ORF	Verified	YLR090W	XDJ1	12	320702	322081	W	Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p
2438	S000004081	ORF	Uncharacterized	YLR091W	n.a.	12	322298	323179	W	Hypothetical protein
2440	S000004082	ORF	Verified	YLR092W	SUL2	12	323545	326226	W	High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates
2442	S000004083	ORF	Verified	YLR093C	NYV1	12	327416	326514	C	v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane
2445	S000033560	intron	n.a.	n.a.	n.a.	12	327400	327260	C	n.a.
2446	S000004084	ORF	Verified	YLR094C	GIS3	12	329239	327731	C	Protein of unknown function
2448	S000004085	ORF	Verified	YLR095C	IOC2	12	332116	329678	C	Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif
2450	S000004086	ORF	Verified	YLR096W	KIN2	12	332591	336034	W	Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p
2452	S000004087	ORF	Uncharacterized	YLR097C	HRT3	12	337266	336232	C	Putative nuclear ubiquitin ligase, based on computational analysis of large-scale protein-protein interaction data; has similarity to F-box proteins; identified in association with Cdc53p, Skp1p and Ubi4 in large-scale studies
2454	S000004088	ORF	Verified	YLR098C	CHA4	12	339474	337528	C	Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain; DNA-binding transcriptional activator or CHA1
2456	S000004089	ORF	Verified	YLR099C	ICT1	12	340929	339745	C	Protein of unknown function, null mutation leads to an increase in sensitivity to Calcofluor white; expression of the gene is induced in the presence of isooctane
2458	S000007618	ORF	Uncharacterized	YLR099W-A	n.a.	12	341326	341589	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
2460	S000004090	ORF	Verified	YLR100W	ERG27	12	341811	342854	W	3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs
2462	S000004091	ORF	Dubious	YLR101C	n.a.	12	342962	342567	C	Protein required for cell viability
2464	S000004092	ORF	Verified	YLR102C	APC9	12	343768	342971	C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
2466	S000004093	ORF	Verified	YLR103C	CDC45	12	345942	343990	C	DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes
2468	S000004094	ORF	Uncharacterized	YLR104W	n.a.	12	346586	346981	W	Hypothetical protein
2470	S000004095	ORF	Verified	YLR105C	SEN2	12	348181	347048	C	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease
2472	S000007313	snoRNA	n.a.	snR79	SNR79	12	348511	348428	C	Small nucleolar RNA; small nucleolar RNA
2474	S000004096	ORF	Verified	YLR106C	MDN1	12	363739	349007	C	Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm
2476	S000004097	ORF	Verified	YLR107W	REX3	12	364117	365331	W	RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases
2479	S000006494	snRNA	n.a.	snR6	SNR6	12	366236	366347	W	U6 spliceosomal RNA, interacts with U4; homology to snRNA U6, interacts with snr14
2481	S000004098	ORF	Uncharacterized	YLR108C	n.a.	12	368125	366668	C	Hypothetical protein
2483	S000004099	ORF	Verified	YLR109W	AHP1	12	368782	369312	W	Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p
2485	S000004100	ORF	Verified	YLR110C	CCW12	12	370099	369698	C	Cell wall protein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor
2487	S000004101	ORF	Dubious	YLR111W	n.a.	12	370392	370724	W	Hypothetical protein
2489	S000004102	ORF	Dubious	YLR112W	n.a.	12	370792	371211	W	Hypothetical protein
2491	S000004103	ORF	Verified	YLR113W	HOG1	12	371621	372928	W	Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p
2494	S000006704	tRNA	n.a.	tR(ACG)L	n.a.	12	374356	374428	W	tRNA-Arg
2496	S000004104	ORF	Uncharacterized	YLR114C	n.a.	12	377239	374945	C	PHO85 Requiring
2498	S000004105	ORF	Verified	YLR115W	CFT2	12	377986	380565	W	Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein.
2500	S000004106	ORF	Verified	YLR116W	MSL5	12	380823	382253	W	Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA
2502	S000004107	ORF	Verified	YLR117C	CLF1	12	384535	382472	C	Essential splicesome assembly factor; contains multiple tetratricopeptide repeat (TPR) protein-binding motifs and interacts specifically with many spliceosome components, may serve as a scaffold during splicesome assembly
2504	S000004108	ORF	Uncharacterized	YLR118C	n.a.	12	385409	384726	C	ORF, Uncharacterized
2506	S000004109	ORF	Verified	YLR119W	SRN2	12	385535	386176	W	Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; suppressor of rna1-1 mutation; may be involved in RNA export from nucleus
2508	S000004110	ORF	Verified	YLR120C	YPS1	12	388221	386512	C	Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
2510	S000028674	ORF	Dubious	YLR120W-A	n.a.	12	388673	388774	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2512	S000004111	ORF	Verified	YLR121C	YPS3	12	390271	388745	C	Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
2514	S000004112	ORF	Dubious	YLR122C	n.a.	12	391332	390955	C	Hypothetical protein
2516	S000004113	ORF	Dubious	YLR123C	n.a.	12	391408	391079	C	contains characteristic aminoacyl-tRNA motif
2518	S000004114	ORF	Dubious	YLR124W	n.a.	12	391601	391945	W	Hypothetical protein
2520	S000004115	ORF	Uncharacterized	YLR125W	n.a.	12	393485	393895	W	Hypothetical protein
2522	S000004116	ORF	Uncharacterized	YLR126C	n.a.	12	395521	394766	C	Hypothetical protein
2524	S000004117	ORF	Verified	YLR127C	APC2	12	398320	395759	C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; similar to cullin Cdc53p
2526	S000004118	ORF	Verified	YLR128W	DCN1	12	398531	399434	W	Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain
2529	S000035289	intron	n.a.	n.a.	n.a.	12	398534	398627	W	n.a.
2530	S000004119	ORF	Verified	YLR129W	DIP2	12	399658	402489	W	Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex
2532	S000004120	ORF	Verified	YLR130C	ZRT2	12	404063	402795	C	Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor
2534	S000004121	ORF	Verified	YLR131C	ACE2	12	406823	404511	C	Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate
2536	S000004122	ORF	Uncharacterized	YLR132C	n.a.	12	408156	407284	C	Protein required for cell viability
2538	S000004123	ORF	Verified	YLR133W	CKI1	12	408446	410194	W	choline kinase
2540	S000004124	ORF	Verified	YLR134W	PDC5	12	410724	412415	W	Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism
2542	S000004125	ORF	Verified	YLR135W	SLX4	12	413282	415528	W	Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
2544	S000004126	ORF	Verified	YLR136C	TIS11	12	416659	415802	C	mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis
2546	S000004127	ORF	Uncharacterized	YLR137W	n.a.	12	417007	418110	W	Hypothetical protein
2548	S000004128	ORF	Verified	YLR138W	NHA1	12	418438	421395	W	Na+/H+ antiporter involved in sodium and potassium efflux through the plasma membrane; required for alkali cation tolerance at acidic pH
2550	S000004129	ORF	Verified	YLR139C	SLS1	12	423474	421543	C	Mitochondrial membrane protein required for assembly of respiratory-chain enzyme complexes III and IV; coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery
2552	S000004130	ORF	Dubious	YLR140W	n.a.	12	423475	423801	W	Protein required for cell viability
2554	S000004131	ORF	Verified	YLR141W	RRN5	12	423684	424775	W	Transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p, involved in transcription of rDNA by RNA polymerase I
2556	S000004132	ORF	Verified	YLR142W	PUT1	12	425187	426617	W	Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source
2558	S000006541	tRNA	n.a.	tD(GUC)L1	n.a.	12	427133	427204	W	tRNA-Asp
2560	S000004133	ORF	Uncharacterized	YLR143W	n.a.	12	427330	429387	W	Hypothetical protein
2562	S000004134	ORF	Verified	YLR144C	ACF2	12	432017	429678	C	Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly
2564	S000004135	ORF	Verified	YLR145W	RMP1	12	432169	432774	W	Protein required for cell viability, component of RNase MRP, which is involved in RNA processing in mitochondria
2566	S000004136	ORF	Verified	YLR146C	SPE4	12	433726	432824	C	Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
2568	S000004137	ORF	Verified	YLR147C	SMD3	12	434464	434159	C	involved in snRNP biogenesis and pre-mRNA splicing; encodes a core snRNP protein
2570	S000004138	ORF	Verified	YLR148W	PEP3	12	434642	437398	W	Vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis, forms complex with Pep5p that mediates protein transport to the vacuole
2572	S000004139	ORF	Uncharacterized	YLR149C	n.a.	12	439824	437632	C	Hypothetical protein
2574	S000007619	ORF	Dubious	YLR149C-A	n.a.	12	440457	440371	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
2576	S000004140	ORF	Verified	YLR150W	STM1	12	440468	441289	W	Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations
2578	S000004141	ORF	Verified	YLR151C	PCD1	12	442738	441716	C	Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids
2580	S000004142	ORF	Uncharacterized	YLR152C	n.a.	12	444689	442959	C	Hypothetical protein
2582	S000004143	ORF	Verified	YLR153C	ACS2	12	447576	445525	C	Acetyl-coA synthetase isoform, required for growth on glucose; expressed under anaerobic conditions
2584	S000004144	ORF	Verified	YLR154C	RNH203	12	448315	447983	C	Ribonuclease H2 subunit, required for RNase H2 activity
2586	S000006699	tRNA	n.a.	tQ(UUG)L	n.a.	12	448722	448651	C	tRNA-Gln
2589	S000029718	rRNA	n.a.	ETS2-1	ETS2-1	12	451786	451576	C	Non-coding region located adjacent to and downstream of RDN25, transcribed as part of the 35S rRNA precursor transcript; contains the primary rRNA transcription termination site at +93 and a secondary termination site between +211 and +250
2591	S000028675	ORF	Dubious	YLR154W-A	n.a.	12	452439	452624	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; encoded within the the 25S rRNA gene on the opposite strand
2593	S000028563	ORF	Dubious	YLR154W-B	n.a.	12	454393	454557	W	Identified by fungal homology and RT-PCR; encoded within the the 25S rRNA gene on the opposite strand
2595	S000028422	ORF	Verified	YLR154W-C	TAR1	12	454697	455071	W	Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand
2597	S000006484	rRNA	n.a.	RDN25-1	RDN25-1	12	455182	451787	C	25S ribosomal RNA, component of the large (60S) ribosomal subunit; encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript
2599	S000029716	rRNA	n.a.	ITS2-1	ITS2-1	12	455414	455183	C	Non-coding region, between RDN58 and RDN25, that is transcribed as part of the 35S rRNA precursor transcript; forms a stem-loop structure that is required for processing of the precursor transcript
2601	S000028676	ORF	Dubious	YLR154W-E	n.a.	12	455434	455637	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; encoded within the the 35S rRNA transcript on the opposite strand
2603	S000006488	rRNA	n.a.	RDN58-1	RDN58-1	12	455572	455415	C	5.8S ribosomal RNA, component of the 60S ribosomal subunit; encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript; 3' end formation involves processing by the exosome complex while 5' end is generated by Kem1p and Rat1p
2605	S000028843	ORF	Dubious	YLR154W-F	n.a.	12	455884	456024	W	Identified by expression profiling and mass spectrometry; encoded within the the 35S rRNA transcript on the opposite strand
2607	S000029715	rRNA	n.a.	ITS1-1	ITS1-1	12	455933	455573	C	Non-coding region, between RDN58 and RDN18, that is transcribed as part of the 35S rRNA precursor transcript; excision during transcript maturation is coupled with processing of the 3' external transcribed spacer (3'ETS)
2609	S000006482	rRNA	n.a.	RDN18-1	RDN18-1	12	457733	455934	C	18S ribosomal RNA, component of the small (40S) ribosomal subunit; involved in codon recognition by tRNAs or the release factor eRF1 (Sup45p); encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript
2611	S000029717	rRNA	n.a.	ETS1-1	ETS1-1	12	458433	457734	C	Non-coding region, located immediately upstream of RDN18, that is transcribed as part of the 35S rRNA precursor transcript; contains an essential U3 snoRNA binding site required for maturation of 18S rRNA
2613	S000006486	rRNA	n.a.	RDN37-1	RDN37-1	12	458433	451576	C	35S ribosomal RNA transcript, encoded by the RDN1 locus, that is processed into the 25S, 18S and 5.8S rRNAs (represented by the RDN25, RDN18, and RDN58 loci)
2621	S000029329	rRNA	n.a.	NTS2-1	n.a.	12	459676	458434	C	Nontranscribed region of the rDNA repeat, located between RND5 and the 5'ETS; contains RNA polymerase I termination site
2623	S000006479	rRNA	n.a.	RDN5-1	RDN5-1	12	459677	459797	W	5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA
2625	S000029714	rRNA	n.a.	NTS1-2	n.a.	12	460712	459798	C	Non-transcribed region of the rDNA repeat located between the 3' ETS and RDN5, required for rDNA repeat expansion
2627	S000029713	rRNA	n.a.	ETS2-2	ETS2-2	12	460923	460713	C	Non-coding region located adjacent to and downstream of RDN25, transcribed as part of the 35S rRNA precursor transcript; contains the primary rRNA transcription termination site at +93 and a secondary termination site between +211 and +250; Non-coding region located adjacent to and downstream of RDN25, transcribed as part of the 35S rRNA precursor transcript; excision during transcript maturation is coupled with processing of ITS1 (internal transcribed spacer 1)
2629	S000028561	ORF	Uncharacterized	YLR154C-G	n.a.	12	462672	462523	C	Identified by fungal homology and RT-PCR
2631	S000006485	rRNA	n.a.	RDN25-2	RDN25-2	12	464319	460924	C	25S ribosomal RNA, component of the large (60S) ribosomal subunit; encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript
2633	S000029712	rRNA	n.a.	ITS2-2	ITS2-2	12	464551	464320	C	Non-coding region between RDN58 and RDN25, transcribed as part of the 35S rRNA precursor transcript; forms a stem-loop structure required for processing of the precursor transcript
2635	S000006489	rRNA	n.a.	RDN58-2	RDN58-2	12	464709	464552	C	5.8S ribosomal RNA, component of the 60S ribosomal subunit; encoded in the rDNA repeat (RDN1)
2637	S000029709	rRNA	n.a.	ITS1-2	ITS1-2	12	465070	464710	C	Non-coding region between RDN58 and RDN18, transcribed as part of the 35S rRNA precursor transcript; excision during transcript maturation is coupled with processing of the 3' external transcribed spacer (3' ETS)
2639	S000006483	rRNA	n.a.	RDN18-2	RDN18-2	12	466870	465071	C	18S ribosomal RNA, component of the small (40S) ribosomal subunit; involved in codon recognition by tRNAs or the release factor eRF1 (Sup45p); encoded in the rDNA repeat (RDN1) as part of the 35S primary transcript
2641	S000029707	rRNA	n.a.	ETS1-2	ETS1-2	12	467570	466871	C	Non-coding region located immediately upstream of RDN18, transcribed as part of the 35S rRNA precursor transcript; contains an essential U3 snoRNA binding site required for maturation of 18S rRNA
2643	S000006487	rRNA	n.a.	RDN37-2	RDN37-2	12	467570	460713	C	35S ribosomal RNA transcript, encoded by the RDN1 locus, that is processed into the 25S, 18S and 5.8S rRNAs (represented by the RDN25, RDN18, and RDN58 loci)
2651	S000029706	rRNA	n.a.	NTS2-2	n.a.	12	468813	467571	C	Non-transcribed region of the rDNA repeat, located between RDN5 and the 5' ETS
2653	S000006480	rRNA	n.a.	RDN5-2	RDN5-2	12	468814	468932	W	5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA
2655	S000028562	ORF	Uncharacterized	YLR154C-H	n.a.	12	468959	468828	C	Identified by fungal homology and RT-PCR
2657	S000004145	ORF	Verified	YLR155C	ASP3-1	12	470406	469318	C	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
2659	S000004146	ORF	Uncharacterized	YLR156W	n.a.	12	472114	472458	W	YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12.
2661	S000006481	rRNA	n.a.	RDN5-3	RDN5-3	12	472466	472584	W	5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA
2663	S000028564	ORF	Uncharacterized	YLR156C-A	n.a.	12	472611	472480	C	Identified by fungal homology and RT-PCR
2665	S000004147	ORF	Verified	YLR157C	ASP3-2	12	474058	472970	C	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
2667	S000028677	ORF	Uncharacterized	YLR157W-D	n.a.	12	475765	475977	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2676	S000028678	ORF	Uncharacterized	YLR157W-E	n.a.	12	481874	482038	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
2680	S000029708	rRNA	n.a.	RDN5-4	RDN5-4	12	482046	482164	W	5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA
2682	S000028565	ORF	Uncharacterized	YLR157C-C	n.a.	12	482191	482060	C	Identified by fungal homology and RT-PCR
2684	S000004148	ORF	Verified	YLR158C	ASP3-3	12	483638	482550	C	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
2686	S000004149	ORF	Uncharacterized	YLR159W	n.a.	12	485346	485690	W	Note: YLR156W, YLR159W, and YLR161W are identical.
2688	S000029710	rRNA	n.a.	RDN5-5	RDN5-5	12	485698	485816	W	5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA
2690	S000028566	ORF	Uncharacterized	YLR159C-A	n.a.	12	485843	485712	C	Identified by fungal homology and RT-PCR
2692	S000004150	ORF	Verified	YLR160C	ASP3-4	12	487290	486202	C	Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C
2694	S000004151	ORF	Uncharacterized	YLR161W	n.a.	12	488998	489342	W	Note: YLR156W, YLR159W, and YLR161W are identical.
2696	S000029711	rRNA	n.a.	RDN5-6	RDN5-6	12	489350	489470	W	5S ribosomal RNA, component of the large (60S) ribosomal subunit; localized to the nucleolus via interaction with Rpl5p; may play a role in maintenance of translational frame; transcription is mediated by PolIII and activated by TFIIIA
2698	S000004152	ORF	Uncharacterized	YLR162W	n.a.	12	489574	489930	W	Protein of unknown function; overexpression confers resistance to the antimicrobial peptide MiAMP1
2700	S000028567	ORF	Uncharacterized	YLR162W-A	n.a.	12	490407	490595	W	Identified by fungal homology and RT-PCR
2702	S000028844	ORF	Dubious	YLR163W-A	n.a.	12	492814	492927	W	Identified by expression profiling and mass spectrometry
2704	S000004153	ORF	Verified	YLR163C	MAS1	12	493256	491868	C	Smaller subunit of the mitochondrial processing protease, essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins
2706	S000004154	ORF	Uncharacterized	YLR164W	n.a.	12	493885	494391	W	YLR164Wp is homologous to TIM18p
2708	S000004155	ORF	Verified	YLR165C	PUS5	12	495260	494496	C	Pseudouridine synthase, catalyzes only the formation of pseudouridine (Psi)-2819 in mitochondrial 21S rRNA; not essential for viability
2710	S000004156	ORF	Verified	YLR166C	SEC10	12	498046	495431	C	Essential 100kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
2712	S000004157	ORF	Verified	YLR167W	RPS31	12	498949	499407	W	Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B
2714	S000004158	ORF	Uncharacterized	YLR168C	n.a.	12	500272	499580	C	possibly involved in intramitochondrial sorting
2716	S000004159	ORF	Dubious	YLR169W	n.a.	12	500337	500690	W	Hypothetical protein
2718	S000004161	ORF	Dubious	YLR171W	n.a.	12	500735	501124	W	Hypothetical protein
2720	S000004160	ORF	Verified	YLR170C	APS1	12	501051	500581	C	Small subunit of the clathrin-associated adaptor complex AP-1, which is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex
2722	S000004162	ORF	Verified	YLR172C	DPH5	12	502164	501262	C	Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm
2724	S000004163	ORF	Uncharacterized	YLR173W	n.a.	12	502423	504249	W	Hypothetical protein
2726	S000004164	ORF	Verified	YLR174W	IDP2	12	504593	505831	W	Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose
2728	S000004165	ORF	Verified	YLR175W	CBF5	12	506136	507587	W	Component of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), probable rRNA pseudouridine synthase, binds to snoRNP Nop10p and also interacts with ribosomal biogenesis protein Nop53p
2730	S000004166	ORF	Verified	YLR176C	RFX1	12	510234	507799	C	Protein involved in DNA damage and replication checkpoint pathway; recruits repressors Tup1p and Cyc8p to promoters of DNA damage-inducible genes; similar to a family of mammalian DNA binding RFX1-4 proteins
2732	S000004167	ORF	Uncharacterized	YLR177W	n.a.	12	511056	512942	W	Hypothetical protein
2734	S000004168	ORF	Verified	YLR178C	TFS1	12	513823	513164	C	Carboxypeptidase Y inhibitor, function requires acetylation by the NatB N-terminal acetyltransferase; phosphatidylethanolamine-binding protein involved in protein kinase A signaling pathway
2736	S000004169	ORF	Uncharacterized	YLR179C	n.a.	12	514715	514110	C	Protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
2738	S000004170	ORF	Verified	YLR180W	SAM1	12	515264	516412	W	S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
2740	S000004171	ORF	Verified	YLR181C	VTA1	12	517672	516680	C	Protein involved in endosomal protein sorting; binds to Vps20 and Vps4 and may regulate Vps4function; has coiled-coil domains; mutants show class E vacuolar-protein sorting defects
2742	S000004172	ORF	Verified	YLR182W	SWI6	12	517942	520353	W	Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate
2744	S000004173	ORF	Verified	YLR183C	TOS4	12	522014	520545	C	Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF
2746	S000004174	ORF	Dubious	YLR184W	n.a.	12	522108	522455	W	Hypothetical protein
2748	S000004175	ORF	Verified	YLR185W	RPL37A	12	522665	523290	W	Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein
2751	S000033907	intron	n.a.	n.a.	n.a.	12	522672	523030	W	n.a.
2752	S000004176	ORF	Verified	YLR186W	EMG1	12	523634	524392	W	Protein required for the maturation of the 18S rRNA and for 40S ribosome production; associated with spindle/microtubules; nuclear localization depends on physical interaction with Nop14p; may bind snoRNAs
2754	S000004177	ORF	Uncharacterized	YLR187W	SKG3	12	524867	527947	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p
2756	S000004178	ORF	Verified	YLR188W	MDL1	12	528302	530389	W	Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress
2758	S000004179	ORF	Verified	YLR189C	ATG26	12	534395	530799	C	UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids, involved in autophagy
2760	S000004180	ORF	Verified	YLR190W	MMR1	12	535216	536691	W	Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p
2762	S000004181	ORF	Verified	YLR191W	PEX13	12	537274	538434	W	Integral peroxisomal membrane receptor for the PTS1 peroxisomal matrix protein signal recognition factor Pex5p, required for the translocation of peroxisomal matrix proteins, also interacts with Pex7p and Pex14p, contains a C-terminal SH3 domain
2764	S000004182	ORF	Verified	YLR192C	HCR1	12	539591	538794	C	Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA
2766	S000004183	ORF	Uncharacterized	YLR193C	n.a.	12	540538	540011	C	Hypothetical protein
2768	S000004184	ORF	Uncharacterized	YLR194C	n.a.	12	541575	540811	C	Hypothetical protein
2770	S000004185	ORF	Verified	YLR195C	NMT1	12	543306	541939	C	N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction
2772	S000004186	ORF	Verified	YLR196W	PWP1	12	543970	545700	W	Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily
2774	S000004187	ORF	Verified	YLR197W	SIK1	12	546099	547613	W	Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects
2776	S000004188	ORF	Dubious	YLR198C	n.a.	12	547647	547288	C	Protein required for cell viability
2778	S000004189	ORF	Uncharacterized	YLR199C	n.a.	12	548771	547855	C	Hypothetical protein
2781	S000030463	intron	n.a.	n.a.	n.a.	12	548765	548680	C	n.a.
2782	S000004190	ORF	Verified	YLR200W	YKE2	12	549014	549358	W	Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin
2784	S000004191	ORF	Uncharacterized	YLR201C	n.a.	12	550295	549513	C	The authentic, non-tagged protein was localized to the mitochondria
2786	S000004192	ORF	Dubious	YLR202C	n.a.	12	550638	550196	C	Hypothetical protein
2789	S000037016	intron	n.a.	n.a.	n.a.	12	550576	550461	C	n.a.
2790	S000004193	ORF	Verified	YLR203C	MSS51	12	551962	550652	C	Nuclear encoded protein required for translation of COX1 mRNA; binds to Cox1 protein
2792	S000004194	ORF	Verified	YLR204W	QRI5	12	552272	552607	W	Mitochondrial protein of unknown function
2794	S000004195	ORF	Verified	YLR205C	HMX1	12	553679	552726	C	ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxygenase activity despite similarity to heme oxygenases; expression regulated by AFT1
2796	S000004196	ORF	Verified	YLR206W	ENT2	12	554580	556421	W	Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus
2798	S000004197	ORF	Verified	YLR207W	HRD3	12	556790	559291	W	Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events
2800	S000004198	ORF	Verified	YLR208W	SEC13	12	559553	560446	W	Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles
2802	S000004199	ORF	Verified	YLR209C	PNP1	12	561734	560799	C	Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides
2804	S000004200	ORF	Verified	YLR210W	CLB4	12	562010	563392	W	B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation
2806	S000004201	ORF	Uncharacterized	YLR211C	n.a.	12	564533	563794	C	Hypothetical protein
2809	S000032248	intron	n.a.	n.a.	n.a.	12	564515	564457	C	n.a.
2810	S000004202	ORF	Verified	YLR212C	TUB4	12	566283	564862	C	Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body
2812	S000004203	ORF	Verified	YLR213C	CRR1	12	567924	566656	C	Protein with similarity to Crh1p, which is a putative glycosidase of the cell wall
2814	S000004204	ORF	Verified	YLR214W	FRE1	12	568569	570629	W	Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels
2816	S000004205	ORF	Verified	YLR215C	CDC123	12	571860	570778	C	Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein
2818	S000004207	ORF	Dubious	YLR217W	n.a.	12	572911	573234	W	Hypothetical protein
2820	S000004206	ORF	Verified	YLR216C	CPR6	12	573213	572098	C	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity
2822	S000004208	ORF	Uncharacterized	YLR218C	n.a.	12	573920	573468	C	Hypothetical protein
2824	S000004209	ORF	Verified	YLR219W	MSC3	12	574153	576339	W	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate
2826	S000004210	ORF	Verified	YLR220W	CCC1	12	576827	577795	W	Functions in the homeostasis of both calcium and manganese ions; Possible transmembrane Ca2+ transporter
2828	S000004211	ORF	Verified	YLR221C	RSA3	12	579026	578364	C	Protein with a likely role in ribosomal maturation, required for accumulation of wild-type levels of large (60S) ribosomal subunits; binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus
2830	S000004212	ORF	Verified	YLR222C	UTP13	12	581773	579320	C	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
2832	S000028568	ORF	Dubious	YLR222C-A	n.a.	12	582238	582008	C	Identified by fungal homology and RT-PCR
2834	S000004213	ORF	Verified	YLR223C	IFH1	12	585492	582235	C	Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate
2836	S000004214	ORF	Uncharacterized	YLR224W	n.a.	12	586466	587575	W	Hypothetical protein
2838	S000004215	ORF	Uncharacterized	YLR225C	n.a.	12	588920	587697	C	Hypothetical protein
2840	S000004216	ORF	Verified	YLR226W	BUR2	12	589356	590543	W	Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II
2842	S000004217	ORF	Verified	YLR227C	ADY4	12	592045	590564	C	Structural component of the meiotic outer plaque, which is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane
2844	S000006655	tRNA	n.a.	tL(UAG)L1	n.a.	12	592621	592521	C	tRNA-Leu
2845	S000035002	intron	n.a.	n.a.	n.a.	12	592583	592565	C	n.a.
2860	S000004218	ORF	Verified	YLR228C	ECM22	12	602465	600021	C	Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription factors; homologous to Upc2p
2862	S000004220	ORF	Dubious	YLR230W	n.a.	12	604576	604881	W	Protein required for cell viability
2864	S000004219	ORF	Verified	YLR229C	CDC42	12	604789	604214	C	Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins
2866	S000006614	tRNA	n.a.	tI(UAU)L	n.a.	12	605434	605302	C	tRNA-Ile
2867	S000035162	intron	n.a.	n.a.	n.a.	12	605397	605338	C	n.a.
2870	S000004222	ORF	Dubious	YLR232W	n.a.	12	606832	607179	W	Hypothetical protein
2872	S000004221	ORF	Verified	YLR231C	BNA5	12	607121	605760	C	Kynureninase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
2874	S000004223	ORF	Verified	YLR233C	EST1	12	609526	607427	C	TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere
2876	S000004224	ORF	Verified	YLR234W	TOP3	12	609785	611755	W	DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination
2878	S000004225	ORF	Dubious	YLR235C	n.a.	12	611932	611534	C	Involved in meiotic nuclear division.
2880	S000004226	ORF	Dubious	YLR236C	n.a.	12	612119	611796	C	Hypothetical protein
2882	S000004227	ORF	Verified	YLR237W	THI7	12	612369	614165	W	Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia
2884	S000004228	ORF	Verified	YLR238W	FAR10	12	614757	616193	W	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate
2886	S000004229	ORF	Verified	YLR239C	LIP2	12	617320	616334	C	Lipoyl ligase, involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups
2888	S000004230	ORF	Verified	YLR240W	VPS34	12	617535	620162	W	Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; similar to p110 subunit of mammalian PI 3-kinase
2890	S000004231	ORF	Uncharacterized	YLR241W	n.a.	12	620475	622823	W	Hypothetical protein
2892	S000004232	ORF	Verified	YLR242C	ARV1	12	623885	622920	C	Protein required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein
2894	S000004233	ORF	Uncharacterized	YLR243W	n.a.	12	624205	625023	W	Protein required for cell viability
2896	S000004234	ORF	Verified	YLR244C	MAP1	12	626333	625170	C	Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p
2898	S000004235	ORF	Verified	YLR245C	CDD1	12	626932	626504	C	Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm
2900	S000004236	ORF	Verified	YLR246W	ERF2	12	627120	628199	W	Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole
2902	S000006643	tRNA	n.a.	tL(CAA)L	n.a.	12	628385	628499	W	tRNA-Leu
2903	S000033796	intron	n.a.	n.a.	n.a.	12	628423	628455	W	n.a.
2906	S000004237	ORF	Uncharacterized	YLR247C	n.a.	12	633356	628686	C	Hypothetical protein
2908	S000004238	ORF	Verified	YLR248W	RCK2	12	634254	636086	W	Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
2910	S000004239	ORF	Verified	YLR249W	YEF3	12	636782	639916	W	Translational elongation factor, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP
2912	S000004240	ORF	Verified	YLR250W	SSP120	12	640319	641023	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
2914	S000004241	ORF	Uncharacterized	YLR251W	SYM1	12	641466	642059	W	Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17
2916	S000004242	ORF	Dubious	YLR252W	n.a.	12	641959	642264	W	Hypothetical protein
2918	S000004243	ORF	Uncharacterized	YLR253W	n.a.	12	642629	644338	W	Hypothetical protein
2920	S000004244	ORF	Uncharacterized	YLR254C	NDL1	12	644975	644406	C	homolog of nuclear distribution factor NudE, NUDEL
2922	S000004245	ORF	Dubious	YLR255C	n.a.	12	645955	645602	C	Hypothetical protein
2924	S000004246	ORF	Verified	YLR256W	HAP1	12	646417	650925	W	Heme-responsive zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; redox sensing regulator of gene expression (activates CYC1, CYC7, CYP3, CYB2, CTT1, COR2, ROX1, ERG9, ERG11, SOD2 and YHB1; represses HEM13)
2931	S000006517	tRNA	n.a.	tA(AGC)L	n.a.	12	657008	656936	C	tRNA-Ala
2935	S000004247	ORF	Uncharacterized	YLR257W	n.a.	12	658828	659793	W	Hypothetical protein
2937	S000004248	ORF	Verified	YLR258W	GSY2	12	660718	662835	W	Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase
2939	S000004249	ORF	Verified	YLR259C	HSP60	12	665004	663286	C	Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; similarity to groEL
2941	S000004250	ORF	Verified	YLR260W	LCB5	12	665846	667909	W	Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules
2943	S000004251	ORF	Dubious	YLR261C	VPS63	12	668565	668239	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene YPT6; deletion causes a vacuolar protein sorting defect
2945	S000004252	ORF	Verified	YLR262C	YPT6	12	668893	668246	C	Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi; has similarity to the human GTPase, Rab6
2947	S000007246	ORF	Uncharacterized	YLR262C-A	n.a.	12	669664	669470	C	Similar to C. elegans protein
2949	S000004253	ORF	Verified	YLR263W	RED1	12	670342	672825	W	Protein involved in chromosome segregation during the first meiotic division; component of the axial elements of the synaptonemal complex; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity
2951	S000004254	ORF	Verified	YLR264W	RPS28B	12	673133	673336	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Bp and has similarity to rat S28 ribosomal protein
2953	S000028808	ORF	Uncharacterized	YLR264C-A	n.a.	12	673946	673830	C	Identified by SAGE
2955	S000004255	ORF	Verified	YLR265C	NEJ1	12	675457	674429	C	Protein involved in regulation of nonhomologous end joining; repressed by MAT heterozygosity; associates with Lif1p and regulates its cellular distribution
2957	S000004256	ORF	Verified	YLR266C	PDR8	12	677726	675621	C	Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon
2959	S000004257	ORF	Uncharacterized	YLR267W	n.a.	12	678214	679926	W	Protein of unknown function, overproduction suppresses a pam1 slv3 double null mutation
2961	S000004258	ORF	Verified	YLR268W	SEC22	12	680202	680846	W	R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog
2963	S000004260	ORF	Verified	YLR270W	DCS1	12	681188	682240	W	Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p
2965	S000004259	ORF	Dubious	YLR269C	n.a.	12	681218	680868	C	Hypothetical protein
2967	S000004261	ORF	Uncharacterized	YLR271W	n.a.	12	682739	683563	W	Hypothetical protein
2969	S000004262	ORF	Verified	YLR272C	YCS4	12	687204	683674	C	Protein required for accurate sister chromatid segregation
2971	S000006762	tRNA	n.a.	tV(AAC)L	n.a.	12	687934	687861	C	tRNA-Val
2975	S000004263	ORF	Verified	YLR273C	PIG1	12	691031	689085	C	Putative type 1 phosphatase regulatory subunit; interacts with Gsy2p; similar to Gac1p
2977	S000004264	ORF	Verified	YLR274W	CDC46	12	691557	693884	W	Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
2979	S000004265	ORF	Verified	YLR275W	SMD2	12	694380	694802	W	U1 snRNP protein of the Sm class
2982	S000030098	intron	n.a.	n.a.	n.a.	12	694385	694474	W	n.a.
2983	S000004266	ORF	Verified	YLR276C	DBP9	12	696832	695048	C	ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit
2985	S000004267	ORF	Verified	YLR277C	YSH1	12	699497	697158	C	Putative endonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex required for 3' processing of mRNAs
2987	S000004268	ORF	Uncharacterized	YLR278C	n.a.	12	704026	700001	C	Protein of unknown function, localizes to the nucleus; potential Cdc28p substrate
2989	S000004269	ORF	Dubious	YLR279W	n.a.	12	704311	704700	W	Hypothetical protein
2991	S000004270	ORF	Dubious	YLR280C	n.a.	12	704835	704485	C	Hypothetical protein
2993	S000004271	ORF	Uncharacterized	YLR281C	n.a.	12	704962	704495	C	Hypothetical protein
2995	S000004273	ORF	Uncharacterized	YLR283W	n.a.	12	705188	706132	W	Hypothetical protein
2997	S000004272	ORF	Dubious	YLR282C	n.a.	12	705414	705073	C	Hypothetical protein
2999	S000004274	ORF	Verified	YLR284C	ECI1	12	707042	706200	C	Peroxisomal delta3,delta2-enoyl-CoA isomerase, hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced
3001	S000004275	ORF	Verified	YLR285W	NNT1	12	707362	708147	W	Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination
3003	S000028569	ORF	Uncharacterized	YLR285C-A	n.a.	12	708340	708170	C	Identified by fungal homology and RT-PCR
3005	S000028679	ORF	Dubious	YLR286W-A	n.a.	12	708564	708698	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3007	S000004276	ORF	Verified	YLR286C	CTS1	12	710138	708450	C	Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p
3009	S000004277	ORF	Uncharacterized	YLR287C	n.a.	12	712060	710993	C	Hypothetical protein
3011	S000004278	ORF	Verified	YLR287C-A	RPS30A	12	713160	712539	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Bp and has similarity to rat S30 ribosomal protein
3014	S000030933	intron	n.a.	n.a.	n.a.	12	713157	712728	C	n.a.
3015	S000004279	ORF	Verified	YLR288C	MEC3	12	714906	713482	C	DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1
3017	S000004280	ORF	Verified	YLR289W	GUF1	12	715091	717028	W	Mitochondrial GTPase of unknown function, similar to E. coli elongation factor-type GTP-binding protein LepA and to LK1236.1 from Caenorhabditis elegans
3019	S000004281	ORF	Uncharacterized	YLR290C	n.a.	12	717980	717147	C	Hypothetical protein
3021	S000004282	ORF	Verified	YLR291C	GCD7	12	719464	718319	C	Beta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression
3023	S000004283	ORF	Verified	YLR292C	SEC72	12	720372	719791	C	Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
3025	S000004284	ORF	Verified	YLR293C	GSP1	12	721432	720773	C	GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Prp20p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog
3027	S000004285	ORF	Dubious	YLR294C	n.a.	12	722032	721703	C	Hypothetical protein
3029	S000004286	ORF	Verified	YLR295C	ATP14	12	722375	722001	C	Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
3031	S000004287	ORF	Dubious	YLR296W	n.a.	12	722980	723306	W	Hypothetical protein
3033	S000004288	ORF	Uncharacterized	YLR297W	n.a.	12	724046	724435	W	Hypothetical protein
3035	S000004289	ORF	Verified	YLR298C	YHC1	12	725418	724723	C	Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site
3037	S000004290	ORF	Verified	YLR299W	ECM38	12	726071	728053	W	Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; expression induced mainly by nitrogen starvation
3039	S000028680	ORF	Dubious	YLR299C-A	n.a.	12	728005	727913	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3041	S000004291	ORF	Verified	YLR300W	EXG1	12	728957	730303	W	Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes
3043	S000004292	ORF	Uncharacterized	YLR301W	n.a.	12	730827	731561	W	Hypothetical protein
3046	S000006656	tRNA	n.a.	tL(UAG)L2	n.a.	12	732092	732192	W	tRNA-Leu
3047	S000035006	intron	n.a.	n.a.	n.a.	12	732130	732148	W	n.a.
3050	S000004294	ORF	Verified	YLR303W	MET17	12	732544	733878	W	O-acetyl homoserine-O-acetyl serine sulfhydrylase, required for sulfur amino acid synthesis
3052	S000004293	ORF	Dubious	YLR302C	n.a.	12	732555	732193	C	Hypothetical protein
3055	S000006607	tRNA	n.a.	tI(AAU)L1	n.a.	12	734804	734877	W	tRNA-Ile
3057	S000004295	ORF	Verified	YLR304C	ACO1	12	737550	735214	C	Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy
3059	S000004296	ORF	Verified	YLR305C	STT4	12	743865	738163	C	Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization
3061	S000004297	ORF	Verified	YLR306W	UBC12	12	744153	744853	W	Enzyme that mediates the conjugation of Rub1p, a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes
3064	S000031520	intron	n.a.	n.a.	n.a.	12	744156	744289	W	n.a.
3065	S000004298	ORF	Verified	YLR307W	CDA1	12	745622	746527	W	Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall
3067	S000028525	ORF	Uncharacterized	YLR307C-A	n.a.	12	747113	746850	C	Identified by homology to <i>Ashbya gossypii</i>
3069	S000004299	ORF	Verified	YLR308W	CDA2	12	747939	748877	W	Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall
3071	S000004300	ORF	Verified	YLR309C	IMH1	12	751771	749036	C	Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi
3073	S000004301	ORF	Verified	YLR310C	CDC25	12	756995	752226	C	Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1
3075	S000004302	ORF	Dubious	YLR311C	n.a.	12	757614	757267	C	Hypothetical protein
3077	S000004303	ORF	Uncharacterized	YLR312C	n.a.	12	758835	757639	C	Hypothetical protein
3079	S000004304	ORF	Verified	YLR312W-A	MRPL15	12	759385	760243	W	Mitochondrial ribosomal protein of the large subunit
3082	S000037405	intron	n.a.	n.a.	n.a.	12	759413	759566	W	n.a.
3083	S000028570	ORF	Uncharacterized	YLR312C-B	n.a.	12	760644	760357	C	Identified by fungal homology and RT-PCR
3085	S000004305	ORF	Verified	YLR313C	SPH1	12	762342	760357	C	Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p
3087	S000004306	ORF	Verified	YLR314C	CDC3	12	764137	762575	C	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
3089	S000004307	ORF	Verified	YLR315W	NKP2	12	764808	765269	W	Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)
3091	S000004309	ORF	Dubious	YLR317W	n.a.	12	765655	766089	W	Dubious ORF, may be part of a bicistronic transcript with NKP2
3093	S000004308	ORF	Verified	YLR316C	TAD3	12	766358	765266	C	Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs
3097	S000035751	intron	n.a.	n.a.	n.a.	12	766129	766074	C	n.a.
3098	S000035750	intron	n.a.	n.a.	n.a.	12	766249	766182	C	n.a.
3099	S000004310	ORF	Verified	YLR318W	EST2	12	766542	769196	W	Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia
3101	S000004311	ORF	Verified	YLR319C	BUD6	12	771684	769318	C	Actin- and formin-interacting protein, involved in actin cable nucleation and polarized cell growth; isolated as bipolar budding mutant; potential Cdc28p substrate
3103	S000004312	ORF	Verified	YLR320W	MMS22	12	771940	776304	W	Protein involved in resistance to ionizing radiation; acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks
3105	S000004314	ORF	Dubious	YLR322W	VPS65	12	777628	777942	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 75% of ORF overlaps the verified gene SFH1; deletion causes a vacuolar protein sorting defect
3107	S000004313	ORF	Verified	YLR321C	SFH1	12	777864	776584	C	Subunit of the RSC chromatin remodeling complex required for kinetochore function in chromosome segregation; essential gene required for cell cycle progression; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog
3109	S000004315	ORF	Verified	YLR323C	CWC24	12	778952	778173	C	Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p
3111	S000004316	ORF	Verified	YLR324W	PEX30	12	779215	780786	W	Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p
3113	S000004317	ORF	Verified	YLR325C	RPL38	12	781379	781143	C	Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein
3115	S000004318	ORF	Uncharacterized	YLR326W	n.a.	12	782174	782896	W	Hypothetical protein
3117	S000004319	ORF	Uncharacterized	YLR327C	n.a.	12	783387	783127	C	Hypothetical protein
3119	S000006732	tRNA	n.a.	tS(GCU)L	n.a.	12	784354	784453	W	tRNA-Ser
3120	S000037471	intron	n.a.	n.a.	n.a.	12	784390	784409	W	n.a.
3123	S000004320	ORF	Verified	YLR328W	NMA1	12	784913	786118	W	Nicotinic acid mononucleotide adenylyltransferase, involved in NAD(+) salvage pathway
3125	S000004321	ORF	Verified	YLR329W	REC102	12	786731	787333	W	Protein involved in early stages of meiotic recombination; required for chromosome synapsis; forms a complex with Rec104p and Spo11p necessary during the initiation of recombination
3127	S000004322	ORF	Verified	YLR330W	CHS5	12	787664	789679	W	Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p localization, also involved in cell fusion during mating
3129	S000004324	ORF	Verified	YLR332W	MID2	12	790676	791806	W	O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p
3131	S000004323	ORF	Dubious	YLR331C	n.a.	12	791046	790669	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 98% of ORF overlaps the verified gene MID2
3134	S000006542	tRNA	n.a.	tD(GUC)L2	n.a.	12	793918	793989	W	tRNA-Asp
3136	S000006452	snoRNA	n.a.	snR61	SNR61	12	794575	794486	C	guides 2'-O-methylation on large subunit rRNA at A1131; small nucleolar RNA snR61
3138	S000006446	snoRNA	n.a.	snR55	SNR55	12	794794	794697	C	guides 2'-O-methylation on small subunit rRNA at U1267; small nucleolar RNA snR55
3140	S000006448	snoRNA	n.a.	snR57	SNR57	12	795024	794937	C	guides 2'-O-methylation on small subunit rRNA at G1571; small nucleolar RNA snR57
3142	S000004325	ORF	Verified	YLR333C	RPS25B	12	795899	795573	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein
3145	S000004326	ORF	Dubious	YLR334C	n.a.	12	797078	796698	C	Hypothetical protein
3147	S000006559	tRNA	n.a.	tE(UUC)L	n.a.	12	797178	797249	W	tRNA-Glu
3149	S000004327	ORF	Verified	YLR335W	NUP2	12	797430	799592	W	Protein involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization
3151	S000004328	ORF	Verified	YLR336C	SGD1	12	802396	799697	C	Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia
3153	S000004330	ORF	Dubious	YLR338W	n.a.	12	804346	805203	W	Hypothetical protein
3155	S000004329	ORF	Verified	YLR337C	VRP1	12	805106	802653	C	Proline-rich, actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP)
3157	S000004332	ORF	Verified	YLR340W	RPP0	12	805887	806825	W	Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302
3159	S000004331	ORF	Dubious	YLR339C	n.a.	12	806335	805784	C	Protein required for cell viability
3161	S000004333	ORF	Verified	YLR341W	SPO77	12	807385	808818	W	Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis
3163	S000004334	ORF	Verified	YLR342W	FKS1	12	809997	815627	W	Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling
3165	S000028571	ORF	Uncharacterized	YLR342W-A	n.a.	12	815810	815983	W	Identified by fungal homology and RT-PCR
3167	S000004335	ORF	Uncharacterized	YLR343W	GAS2	12	816094	817761	W	Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p
3170	S000006706	tRNA	n.a.	tR(CCG)L	TRR4	12	818609	818680	W	tRNA Arg Four; tRNA-Arg
3172	S000004336	ORF	Verified	YLR344W	RPL26A	12	819312	820142	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
3175	S000037240	intron	n.a.	n.a.	n.a.	12	819331	819777	W	n.a.
3176	S000004337	ORF	Uncharacterized	YLR345W	n.a.	12	820511	822040	W	Hypothetical protein
3178	S000004338	ORF	Uncharacterized	YLR346C	n.a.	12	822592	822287	C	Protein of unknown function; expression regulated by PDR1
3180	S000028681	ORF	Dubious	YLR347W-A	n.a.	12	824788	824928	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3182	S000004339	ORF	Verified	YLR347C	KAP95	12	826412	823827	C	Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS), interacts with nucleoporins to guide transport across the nuclear pore complex
3184	S000004341	ORF	Dubious	YLR349W	n.a.	12	827520	828026	W	Hypothetical protein
3186	S000004340	ORF	Verified	YLR348C	DIC1	12	827872	826976	C	Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix
3188	S000004342	ORF	Verified	YLR350W	ORM2	12	828729	829379	W	Evolutionarily conserved protein with similarity to Orm1p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum
3190	S000004343	ORF	Verified	YLR351C	NIT3	12	830363	829488	C	Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member
3192	S000004344	ORF	Uncharacterized	YLR352W	n.a.	12	831115	833538	W	Hypothetical protein
3194	S000004345	ORF	Verified	YLR353W	BUD8	12	834351	836162	W	Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole
3196	S000004346	ORF	Verified	YLR354C	TAL1	12	837356	836349	C	Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate
3198	S000004347	ORF	Verified	YLR355C	ILV5	12	839252	838065	C	Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA
3200	S000004348	ORF	Uncharacterized	YLR356W	n.a.	12	840320	840913	W	Hypothetical protein
3202	S000004349	ORF	Verified	YLR357W	RSC2	12	841330	843999	W	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; required for expression of mid-late sporulation-specific genes; contains two essential  bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook
3204	S000004350	ORF	Dubious	YLR358C	n.a.	12	844049	843486	C	Hypothetical protein
3206	S000004351	ORF	Verified	YLR359W	ADE13	12	844281	845729	W	Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway
3208	S000004352	ORF	Verified	YLR360W	VPS38	12	846102	847421	W	Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity
3210	S000004353	ORF	Uncharacterized	YLR361C	n.a.	12	849123	847387	C	Protein involved in cell cycle regulation
3212	S000028845	ORF	Uncharacterized	YLR361C-A	n.a.	12	849678	849382	C	Identified by expression profiling and mass spectrometry
3214	S000004354	ORF	Verified	YLR362W	STE11	12	849865	852018	W	Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways, where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p
3216	S000004355	ORF	Verified	YLR363C	NMD4	12	853150	852494	C	Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway
3218	S000007620	ORF	Uncharacterized	YLR363W-A	n.a.	12	853460	853717	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
3220	S000004356	ORF	Uncharacterized	YLR364W	n.a.	12	854061	854390	W	Hypothetical protein
3222	S000004357	ORF	Dubious	YLR365W	n.a.	12	855198	855530	W	Hypothetical protein
3224	S000004358	ORF	Dubious	YLR366W	n.a.	12	855537	855842	W	Hypothetical protein
3226	S000028846	ORF	Dubious	YLR364C-A	n.a.	12	855644	855522	C	Identified by expression profiling and mass spectrometry
3228	S000004359	ORF	Verified	YLR367W	RPS22B	12	856441	857316	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins
3231	S000037775	intron	n.a.	n.a.	n.a.	12	856574	857056	W	n.a.
3232	S000006504	snoRNA	n.a.	snR44	SNR44	12	856709	856919	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of small subunit rRNA at position 106 and of large subunit rRNA at position 1055
3234	S000004360	ORF	Verified	YLR368W	MDM30	12	857539	859335	W	F box protein, component of protein ubiquitin ligases; promotes ubiquitin-mediated degradation of Gal4p; required for normal mitochondrial fusion
3236	S000004361	ORF	Verified	YLR369W	SSQ1	12	859551	861524	W	Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia
3238	S000004362	ORF	Verified	YLR370C	ARC18	12	862253	861717	C	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
3240	S000004363	ORF	Verified	YLR371W	ROM2	12	862713	866783	W	GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP
3242	S000004364	ORF	Verified	YLR372W	SUR4	12	867353	868390	W	Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis
3244	S000004365	ORF	Verified	YLR373C	VID22	12	871366	868661	C	Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles
3246	S000004367	ORF	Uncharacterized	YLR375W	n.a.	12	871696	872727	W	Protein involved in pre-tRNA splicing and in uptake of branched-chain amino acids
3248	S000004366	ORF	Dubious	YLR374C	n.a.	12	871841	871452	C	Hypothetical protein
3250	S000004368	ORF	Uncharacterized	YLR376C	PSY3	12	873553	872825	C	Protein of unknown function; deletion results in a mutator phenotype suggesting a role for this protein as a mutational suppressor; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C
3252	S000004369	ORF	Verified	YLR377C	FBP1	12	874791	873745	C	Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism
3254	S000006633	tRNA	n.a.	tK(UUU)L	n.a.	12	875375	875470	W	tRNA-Lys
3255	S000034214	intron	n.a.	n.a.	n.a.	12	875412	875434	W	n.a.
3258	S000004371	ORF	Dubious	YLR379W	n.a.	12	876921	877295	W	Protein required for cell viability
3260	S000004370	ORF	Verified	YLR378C	SEC61	12	877177	875735	C	Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER
3262	S000004372	ORF	Verified	YLR380W	CSR1	12	878282	879508	W	Phosphatidylinositol transfer protein with a potential role in lipid turnover; interacts specifically with thioredoxin peroxidase (Tsa2p) and may have a role in oxidative stress resistance
3264	S000004373	ORF	Verified	YLR381W	CTF3	12	879723	881924	W	Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules
3266	S000004374	ORF	Verified	YLR382C	NAM2	12	884751	882067	C	Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance
3268	S000004375	ORF	Verified	YLR383W	SMC6	12	885288	888632	W	Protein involved in structural maintenance of chromosomes; required for interchromosomal and sister chromatid recombination; homologous to S. pombe rad18
3270	S000004376	ORF	Verified	YLR384C	IKI3	12	892900	888851	C	Subunit of RNA polymerase II elongator histone acetyltransferase complex, involved in maintaining its structural integrity; negatively regulates exocytosis independent of transcription, homolog of human familial dysautonomia (FD) protein
3272	S000004377	ORF	Verified	YLR385C	SWC7	12	893390	892992	C	Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin
3274	S000004378	ORF	Verified	YLR386W	VAC14	12	893628	896270	W	Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; activator of Fab1p
3276	S000004379	ORF	Verified	YLR387C	REH1	12	897672	896374	C	Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains
3278	S000004380	ORF	Verified	YLR388W	RPS29A	12	898651	898821	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins
3280	S000006500	snoRNA	n.a.	snR34	SNR34	12	898987	899536	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at positions 2876 and 2822
3282	S000004381	ORF	Verified	YLR389C	STE23	12	902660	899577	C	Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family
3284	S000004382	ORF	Verified	YLR390W	ECM19	12	903066	903404	W	Non-essential protein of unknown function
3286	S000006429	ORF	Verified	YLR390W-A	CCW14	12	903724	904440	W	Secretory Stress Response protein
3288	S000004384	ORF	Uncharacterized	YLR392C	n.a.	12	906305	904749	C	Hypothetical protein
3290	S000004385	ORF	Verified	YLR393W	ATP10	12	907079	907918	W	Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6
3292	S000004386	ORF	Verified	YLR394W	CST9	12	907950	909398	W	Protein required for synaptonemal complex formation, may have a role in meiotic recombination; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate
3294	S000004387	ORF	Verified	YLR395C	COX8	12	909965	909729	C	Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
3296	S000004388	ORF	Verified	YLR396C	VPS33	12	912310	910235	C	ATP-binding protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport
3298	S000004389	ORF	Verified	YLR397C	AFG2	12	914892	912550	C	ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; may be involved in degradation of aberrant mRNAs
3300	S000004390	ORF	Verified	YLR398C	SKI2	12	919019	915156	C	Putative RNA helicase, involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski3p and Ski8p; required for repressing propagation of dsRNA viruses
3302	S000028682	ORF	Dubious	YLR399W-A	n.a.	12	920869	920973	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3304	S000004391	ORF	Verified	YLR399C	BDF1	12	921596	919536	C	Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p
3306	S000004392	ORF	Dubious	YLR400W	n.a.	12	922063	922536	W	Hypothetical protein
3308	S000004393	ORF	Uncharacterized	YLR401C	DUS3	12	924447	922618	C	Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region
3310	S000004394	ORF	Dubious	YLR402W	n.a.	12	924563	925078	W	Hypothetical protein
3312	S000004395	ORF	Verified	YLR403W	SFP1	12	925566	927617	W	Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation
3314	S000004396	ORF	Uncharacterized	YLR404W	n.a.	12	928741	929598	W	Hypothetical protein
3316	S000004397	ORF	Uncharacterized	YLR405W	DUS4	12	929787	930890	W	Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p
3318	S000004398	ORF	Verified	YLR406C	RPL31B	12	931753	931063	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
3321	S000034913	intron	n.a.	n.a.	n.a.	12	931696	931348	C	n.a.
3322	S000028683	ORF	Uncharacterized	YLR406C-A	n.a.	12	932353	932204	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3324	S000004399	ORF	Uncharacterized	YLR407W	n.a.	12	932965	933654	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
3326	S000004400	ORF	Uncharacterized	YLR408C	n.a.	12	934250	933882	C	Hypothetical protein
3328	S000004401	ORF	Uncharacterized	YLR409C	UTP21	12	937230	934411	C	Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
3330	S000004402	ORF	Verified	YLR410W	VIP1	12	937538	940978	W	Protein of unknown function probably involved in the function of the cortical actin cytoskeleton; putative ortholog of S. pombe asp1+
3341	S000004403	ORF	Verified	YLR411W	CTR3	12	947250	947975	W	High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae
3343	S000004404	ORF	Uncharacterized	YLR412W	n.a.	12	948365	949189	W	Hypothetical protein
3345	S000028572	ORF	Uncharacterized	YLR412C-A	n.a.	12	950469	950263	C	Identified by fungal homology and RT-PCR
3347	S000004405	ORF	Uncharacterized	YLR413W	n.a.	12	951152	953179	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
3349	S000004406	ORF	Uncharacterized	YLR414C	n.a.	12	954140	953349	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, and bud
3351	S000004407	ORF	Uncharacterized	YLR415C	n.a.	12	954593	954255	C	Hypothetical protein
3353	S000004408	ORF	Dubious	YLR416C	n.a.	12	954885	954487	C	Hypothetical protein
3355	S000004409	ORF	Verified	YLR417W	VPS36	12	955006	956706	W	Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome
3357	S000004410	ORF	Verified	YLR418C	CDC73	12	958091	956910	C	Substituent of the Paf1 complex together with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for the expression of certain genes and modification of some histones
3359	S000004411	ORF	Uncharacterized	YLR419W	n.a.	12	958424	962731	W	Hypothetical protein
3361	S000006652	tRNA	n.a.	tL(UAA)L	n.a.	12	963051	962968	C	tRNA-Leu
3364	S000004412	ORF	Verified	YLR420W	URA4	12	963781	964875	W	Dihydrooratase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate
3366	S000004413	ORF	Verified	YLR421C	RPN13	12	965556	965086	C	Subunit of the 19S regulatory particle of the 26S proteasome lid
3368	S000004414	ORF	Uncharacterized	YLR422W	n.a.	12	965893	971691	W	Hypothetical protein
3370	S000004415	ORF	Verified	YLR423C	ATG17	12	973166	971913	C	Protein that interacts with and is required for activation of Apg1p protein kinase; involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway
3372	S000004416	ORF	Uncharacterized	YLR424W	n.a.	12	973391	975517	W	Essential protein present in native splicing complexes; identified as a suppressor of prp38-1, a spliceosomal maturation mutation; cold sensitive alleles accumulate pre-mRNA
3374	S000006672	tRNA	n.a.	tN(GUU)L	n.a.	12	976052	975979	C	tRNA-Asn
3379	S000004417	ORF	Verified	YLR425W	TUS1	12	982890	986813	W	Guanine nucleotide exchange factor (GEF) that functions to modulate Rhop1 activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate
3381	S000004418	ORF	Uncharacterized	YLR426W	n.a.	12	987058	988109	W	Hypothetical protein
3384	S000033426	intron	n.a.	n.a.	n.a.	12	987138	987208	W	n.a.
3385	S000004419	ORF	Uncharacterized	YLR427W	MAG2	12	988424	990436	W	DNA-3-methyladenine glycosidase II that catalyzes of the hydrolysis of alkylated DNA
3387	S000004421	ORF	Verified	YLR429W	CRN1	12	990773	992728	W	Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity
3389	S000004420	ORF	Dubious	YLR428C	n.a.	12	990957	990613	C	Hypothetical protein
3391	S000004422	ORF	Verified	YLR430W	SEN1	12	993430	1000125	W	Nuclear protein, putative helicase required for processing of tRNAs, rRNAs, and small nuclear RNAs; potential Cdc28p substrate
3393	S000004423	ORF	Verified	YLR431C	ATG23	12	1001699	1000338	C	Peripheral membrane protein, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway
3395	S000004424	ORF	Verified	YLR432W	IMD3	12	1002553	1004124	W	Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
3397	S000004425	ORF	Verified	YLR433C	CNA1	12	1006004	1004343	C	Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1
3399	S000004427	ORF	Verified	YLR435W	TSR2	12	1006374	1006991	W	Protein with a potential role in pre-rRNA processing
3401	S000004426	ORF	Dubious	YLR434C	n.a.	12	1006404	1006021	C	Protein of unknown function, mRNA is targeted to the bud via the mRNA transport system involving She2p
3403	S000004428	ORF	Verified	YLR436C	ECM30	12	1011241	1007417	C	Non-essential protein of unknown function
3405	S000004429	ORF	Uncharacterized	YLR437C	n.a.	12	1012019	1011618	C	Hypothetical protein
3407	S000004430	ORF	Verified	YLR438W	CAR2	12	1012497	1013771	W	L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive
3409	S000028684	ORF	Dubious	YLR437C-A	n.a.	12	1012682	1012455	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3411	S000006434	ORF	Verified	YLR438C-A	LSM3	12	1014174	1013905	C	Component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
3413	S000004431	ORF	Verified	YLR439W	MRPL4	12	1014487	1015446	W	Mitochondrial ribosomal protein of the large subunit
3415	S000004432	ORF	Verified	YLR440C	SEC39	12	1017693	1015564	C	Protein of unknown function proposed to be involved in protein secretion
3417	S000004433	ORF	Verified	YLR441C	RPS1A	12	1018904	1018137	C	Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein
3419	S000004434	ORF	Verified	YLR442C	SIR3	12	1022247	1019311	C	Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p
3421	S000004435	ORF	Verified	YLR443W	ECM7	12	1022621	1023967	W	Non-essential protein of unknown function
3423	S000004436	ORF	Dubious	YLR444C	n.a.	12	1023984	1023682	C	Hypothetical protein
3425	S000004437	ORF	Uncharacterized	YLR445W	n.a.	12	1024185	1024833	W	Hypothetical protein
3428	S000031806	intron	n.a.	n.a.	n.a.	12	1024569	1024650	W	n.a.
3429	S000004438	ORF	Uncharacterized	YLR446W	n.a.	12	1025210	1026511	W	Hypothetical protein
3431	S000004439	ORF	Verified	YLR447C	VMA6	12	1027889	1026852	C	Subunit D of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane
3433	S000004440	ORF	Verified	YLR448W	RPL6B	12	1028849	1029763	W	Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA
3436	S000032932	intron	n.a.	n.a.	n.a.	12	1028864	1029247	W	n.a.
3437	S000004441	ORF	Verified	YLR449W	FPR4	12	1030829	1032007	W	Nuclear protein, putative peptidyl-prolyl cis-trans isomerase (PPIase) with similarity to Fpr3p; overproduction suppresses the growth defect resulting from the absence of E3 ubiquitin-protein ligase Tom1p
3439	S000004442	ORF	Verified	YLR450W	HMG2	12	1032623	1035760	W	One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks
3441	S000004443	ORF	Verified	YLR451W	LEU3	12	1036089	1038749	W	Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis
3443	S000004444	ORF	Verified	YLR452C	SST2	12	1041363	1039267	C	GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family
3445	S000004445	ORF	Verified	YLR453C	RIF2	12	1042983	1041796	C	Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation
3447	S000004446	ORF	Uncharacterized	YLR454W	n.a.	12	1043995	1051881	W	The authentic, non-tagged protein was localized to the mitochondria
3449	S000006608	tRNA	n.a.	tI(AAU)L2	n.a.	12	1052141	1052068	C	tRNA-Ile
3452	S000004447	ORF	Uncharacterized	YLR455W	n.a.	12	1053626	1054540	W	Hypothetical protein
3454	S000004448	ORF	Uncharacterized	YLR456W	n.a.	12	1055067	1055681	W	Hypothetical protein
3456	S000004450	ORF	Dubious	YLR458W	n.a.	12	1056452	1056832	W	Protein required for cell viability
3458	S000004449	ORF	Verified	YLR457C	NBP1	12	1056768	1055809	C	Component of the mitotic apparatus containing a coiled-coil domain, essential for the G2/M transition
3460	S000004451	ORF	Verified	YLR459W	GAB1	12	1057331	1058515	W	GPI transamidase subunit, involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI
3462	S000004452	ORF	Uncharacterized	YLR460C	n.a.	12	1060884	1059754	C	Hypothetical protein
3464	S000004453	ORF	Verified	YLR461W	PAU4	12	1062916	1063278	W	Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
3475	S000004454	ORF	Uncharacterized	YLR462W	n.a.	12	1065953	1066561	W	Hypothetical protein
3477	S000004456	ORF	Uncharacterized	YLR464W	n.a.	12	1066569	1067498	W	Hypothetical protein
3480	S000031006	intron	n.a.	n.a.	n.a.	12	1067082	1067360	W	n.a.
3481	S000004455	ORF	Dubious	YLR463C	n.a.	12	1066813	1066262	C	Hypothetical protein
3483	S000004458	ORF	Verified	YLR466W	YRF1-4	12	1067084	1071232	W	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
3485	S000004457	ORF	Dubious	YLR465C	BSC3	12	1067350	1067042	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 100% of YLR465C overlaps the uncharacterized ORF YLR464W and 86% of YLR465C overlaps the verified gene YRF1-4
3487	S000028685	ORF	Dubious	YLR466C-A	n.a.	12	1070866	1070384	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3493	S000028686	ORF	Uncharacterized	YLR466C-B	n.a.	12	1071707	1071591	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3495	S000004459	ORF	Verified	YLR467W	YRF1-5	12	1072505	1077895	W	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
3497	S000028687	ORF	Dubious	YLR467C-A	n.a.	12	1077529	1077047	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3501	S000028690	ORF	Dubious	YML133W-B	n.a.	13	827	1309	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3503	S000028689	ORF	Dubious	YML133W-A	n.a.	13	1610	2185	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3505	S000004602	ORF	Uncharacterized	YML133C	n.a.	13	4684	461	C	Hypothetical protein
3508	S000033212	intron	n.a.	n.a.	n.a.	13	3890	3792	C	n.a.
3517	S000004601	ORF	Verified	YML132W	COS3	13	7244	8383	W	Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of a family of conserved, often subtelomerically-encoded proteins
3519	S000004600	ORF	Uncharacterized	YML131W	n.a.	13	10199	11296	W	Hypothetical protein
3521	S000004599	ORF	Verified	YML130C	ERO1	13	13175	11484	C	Glycoprotein required for oxidative protein folding in the endoplasmic reticulum
3523	S000004598	ORF	Verified	YML129C	COX14	13	14754	14542	C	Mitochondrial membrane protein, required for assembly of cytochrome c oxidase
3525	S000004597	ORF	Verified	YML128C	MSC1	13	16677	15136	C	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc1 mutants are defective in directing meiotic recombination events to homologous chromatids
3527	S000004596	ORF	Verified	YML127W	RSC9	13	17065	18810	W	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway
3529	S000004595	ORF	Verified	YML126C	ERG13	13	20536	19061	C	3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis
3531	S000004594	ORF	Uncharacterized	YML125C	n.a.	13	21700	20762	C	Protein required for cell viability
3533	S000004593	ORF	Verified	YML124C	TUB3	13	23684	22049	C	Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p
3536	S000037764	intron	n.a.	n.a.	n.a.	13	23659	23362	C	n.a.
3537	S000004592	ORF	Verified	YML123C	PHO84	13	25801	24038	C	High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p
3539	S000004591	ORF	Dubious	YML122C	n.a.	13	26419	26039	C	Hypothetical protein
3541	S000004590	ORF	Verified	YML121W	GTR1	13	26930	27862	W	Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle, through its homolog and binding partner, Gtr2p; involved in phosphate transport and invasive growth; human RagA and RagB proteins are functional homologs
3543	S000004589	ORF	Verified	YML120C	NDI1	13	29807	28266	C	NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I which is absent in S. cerevisiae
3545	S000004588	ORF	Uncharacterized	YML119W	n.a.	13	30611	31684	W	Protein of unknown function, potential Cdc28p substrate
3547	S000004587	ORF	Verified	YML118W	NGL3	13	32334	33851	W	Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p
3549	S000004585	ORF	Uncharacterized	YML117W	NAB6	13	34243	37647	W	Putative RNA-binding protein, based on computational analysis of large-scale protein-protein interaction data
3551	S000004586	ORF	Dubious	YML116W-A	n.a.	13	37472	37774	W	Hypothetical protein
3553	S000004584	ORF	Verified	YML116W	ATR1	13	38196	39824	W	Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide
3555	S000004583	ORF	Verified	YML115C	VAN1	13	41794	40187	C	Component of the mannan polymerase I; forms a complex with Mnn9p, which is involved in in mannan synthesis; mutants are vanadate-resistant
3557	S000004582	ORF	Verified	YML114C	TAF8	13	43575	42043	C	TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation
3559	S000004581	ORF	Verified	YML113W	DAT1	13	44045	44791	W	DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability
3561	S000004580	ORF	Verified	YML112W	CTK3	13	45063	45953	W	Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing
3563	S000004579	ORF	Verified	YML111W	BUL2	13	46942	49704	W	Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1
3565	S000004578	ORF	Verified	YML110C	COQ5	13	50954	50031	C	2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; located in mitochondria
3567	S000004577	ORF	Verified	YML109W	ZDS2	13	51640	54468	W	Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; paralog of Zds1p
3569	S000004576	ORF	Uncharacterized	YML108W	n.a.	13	54793	55110	W	defines a new subfamily of the split beta-alpha-beta sandwiches.
3571	S000004575	ORF	Uncharacterized	YML107C	n.a.	13	56269	55265	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
3573	S000004574	ORF	Verified	YML106W	URA5	13	56773	57453	W	One of two orotate phosphoribosyltransferase isozymes (see also URA10) that catalyze the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate
3575	S000004573	ORF	Verified	YML105C	SEC65	13	58687	57866	C	Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19
3577	S000004572	ORF	Verified	YML104C	MDM1	13	62322	58939	C	Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds
3579	S000004571	ORF	Verified	YML103C	NUP188	13	67549	62582	C	Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p
3581	S000004570	ORF	Verified	YML102W	CAC2	13	68294	69700	W	Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans
3583	S000004569	ORF	Dubious	YML101C-A	n.a.	13	69726	69409	C	Hypothetical protein
3585	S000004568	ORF	Uncharacterized	YML101C	CUE4	13	70088	69735	C	Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination
3587	S000028688	ORF	Uncharacterized	YML100W-A	n.a.	13	70138	70311	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3589	S000004566	ORF	Verified	YML100W	TSL1	13	70624	73920	W	Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, homologous to Tps3p and may share function
3591	S000004567	ORF	Dubious	YML099W-A	n.a.	13	74229	74558	W	Hypothetical protein
3593	S000004565	ORF	Verified	YML099C	ARG81	13	77040	74398	C	Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p
3595	S000004564	ORF	Verified	YML098W	TAF13	13	77267	77770	W	TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors
3597	S000004563	ORF	Verified	YML097C	VPS9	13	79690	78335	C	Protein required for Golgi to vacuole trafficking, has similarity with mammalian ras inhibitors
3599	S000004562	ORF	Uncharacterized	YML096W	n.a.	13	79909	81486	W	Hypothetical protein
3601	S000004560	ORF	Verified	YML095C	RAD10	13	82113	81481	C	Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein
3603	S000004559	ORF	Verified	YML094W	GIM5	13	82275	82849	W	Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
3606	S000030922	intron	n.a.	n.a.	n.a.	13	82291	82373	W	n.a.
3607	S000004561	ORF	Dubious	YML094C-A	n.a.	13	82620	82219	C	Hypothetical protein
3609	S000004558	ORF	Verified	YML093W	UTP14	13	83090	85789	W	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
3611	S000004557	ORF	Verified	YML092C	PRE8	13	86739	85987	C	20S proteasome beta-type subunit
3613	S000004556	ORF	Verified	YML091C	RPM2	13	90731	87123	C	Protein component of mitochondrial RNase P, along with the mitochondrially-encoded RNA subunit RPM1; Rnase P removes 5' extensions from tRNA precursors; Rpm2p is also involved in maturation of RPM1 and in translation of mitochondrial mRNAs
3615	S000004555	ORF	Dubious	YML090W	n.a.	13	90744	91130	W	Hypothetical protein
3617	S000004554	ORF	Dubious	YML089C	n.a.	13	91409	91041	C	Hypothetical protein
3619	S000004553	ORF	Verified	YML088W	UFO1	13	92235	94241	W	F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation
3621	S000004552	ORF	Uncharacterized	YML087C	n.a.	13	95369	94431	C	Hypothetical protein
3623	S000004551	ORF	Verified	YML086C	ALO1	13	97371	95791	C	D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of D-erythroascorbic acid, which is protective against oxidative stress
3625	S000004550	ORF	Verified	YML085C	TUB1	13	99400	97941	C	Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules
3628	S000035129	intron	n.a.	n.a.	n.a.	13	99375	99260	C	n.a.
3629	S000004549	ORF	Dubious	YML084W	n.a.	13	99489	99797	W	Hypothetical protein
3631	S000004548	ORF	Uncharacterized	YML083C	n.a.	13	101050	99794	C	Hypothetical protein
3633	S000004547	ORF	Uncharacterized	YML082W	n.a.	13	101862	103811	W	Hypothetical protein
3635	S000007247	ORF	Verified	YML081C-A	ATP18	13	104162	103983	C	Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms
3637	S000004546	ORF	Uncharacterized	YML081W	n.a.	13	104777	108532	W	Hypothetical protein
3639	S000004545	ORF	Verified	YML080W	DUS1	13	108806	110077	W	Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17
3641	S000004544	ORF	Uncharacterized	YML079W	n.a.	13	110247	110852	W	Uncharacterized protein with structural resemblance to plant storage and ligand binding proteins (canavalin, glycinin, auxin binding protein), and also to some plant and bacterial enzymes (epimerase, germin)
3643	S000004543	ORF	Verified	YML078W	CPR3	13	111002	111550	W	Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria
3645	S000004542	ORF	Verified	YML077W	BET5	13	111865	112344	W	Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi
3647	S000004541	ORF	Verified	YML076C	WAR1	13	115347	112513	C	Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively
3649	S000004540	ORF	Verified	YML075C	HMG1	13	118898	115734	C	One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae
3651	S000004539	ORF	Verified	YML074C	FPR3	13	121324	120089	C	Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p
3653	S000004538	ORF	Verified	YML073C	RPL6A	13	124172	123227	C	N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA
3656	S000037685	intron	n.a.	n.a.	n.a.	13	124157	123743	C	n.a.
3657	S000004537	ORF	Verified	YML072C	TCB3	13	129367	124730	C	Contains three calcium and lipid binding domains; localized to the bud; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; mRNA is targeted to the bud via the mRNA transport system involving She2p; C-terminal portion of Tcb1p, Tcb2p and Tcb3p interact
3659	S000004536	ORF	Verified	YML071C	COG8	13	131572	129749	C	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
3661	S000006718	tRNA	n.a.	tR(UCU)M2	n.a.	13	131896	131825	C	tRNA-Arg
3664	S000004535	ORF	Verified	YML070W	DAK1	13	133475	135229	W	Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
3666	S000004534	ORF	Verified	YML069W	POB3	13	135500	137158	W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure
3668	S000004533	ORF	Verified	YML068W	ITT1	13	137550	138944	W	Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins
3670	S000004532	ORF	Verified	YML067C	ERV41	13	140214	139063	C	Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport
3673	S000035440	intron	n.a.	n.a.	n.a.	13	140183	140091	C	n.a.
3674	S000004531	ORF	Verified	YML066C	SMA2	13	141533	140424	C	Protein of unknown function involved in the assembly of the prospore membrane during sporulation
3676	S000004530	ORF	Verified	YML065W	ORC1	13	142210	144954	W	Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p
3678	S000004529	ORF	Verified	YML064C	TEM1	13	145876	145139	C	Gtp-binding protein of the ras superfamily involved in termination of M-phase; GTP-binding protein, RAS superfamily
3680	S000004528	ORF	Verified	YML063W	RPS1B	13	146482	147249	W	Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein
3682	S000004527	ORF	Verified	YML062C	MFT1	13	148683	147505	C	Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination
3684	S000004526	ORF	Verified	YML061C	PIF1	13	151532	148953	C	DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA
3686	S000004525	ORF	Verified	YML060W	OGG1	13	151871	153001	W	Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA
3688	S000004524	ORF	Verified	YML059C	NTE1	13	158258	153219	C	Serine esterase that deacylates exogenous lysophospholipids, homolog of human neuropathy target esterase (NTE); mammalian NTE1 deacylates phosphatidylcholine to glycerophosphocholine
3690	S000007472	ORF	Verified	YML058W-A	HUG1	13	158760	158966	W	Protein involved in the Mec1p-mediated checkpoint pathway that responds to DNA damage or replication arrest, transcription is induced by DNA damage
3692	S000004523	ORF	Verified	YML058W	SML1	13	159383	159697	W	Ribonucleotide reductase inhibitor involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase
3694	S000004521	ORF	Verified	YML057W	CMP2	13	160180	161994	W	Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1
3696	S000004522	ORF	Dubious	YML057C-A	n.a.	13	160412	160023	C	Hypothetical protein
3698	S000006445	snoRNA	n.a.	snR54	SNR54	13	163620	163535	C	guides 2'-O-methylation on small subunit rRNA at A973; small nucleolar RNA snR54
3700	S000004520	ORF	Verified	YML056C	IMD4	13	164176	162194	C	Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed
3703	S000031023	intron	n.a.	n.a.	n.a.	13	163716	163309	C	n.a.
3704	S000004519	ORF	Verified	YML055W	SPC2	13	164790	165326	W	Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25
3706	S000004518	ORF	Verified	YML054C	CYB2	13	167308	165533	C	Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions
3708	S000028573	ORF	Uncharacterized	YML054C-A	n.a.	13	167781	167623	C	Identified by fungal homology and RT-PCR
3711	S000006783	tRNA	n.a.	tY(GUA)M1	SUP5	13	168795	168883	W	tRNA-Tyr
3712	S000032294	intron	n.a.	n.a.	n.a.	13	168834	168847	W	n.a.
3715	S000004517	ORF	Uncharacterized	YML053C	n.a.	13	169754	169116	C	Hypothetical protein
3717	S000004516	ORF	Verified	YML052W	SUR7	13	170402	171310	W	Integral membrane protein localized to cortical patch structures; multicopy suppressor of rvs167 mutation; mutants show defects in sporulation and altered sphingolipid content in plasma membrane
3719	S000004515	ORF	Verified	YML051W	GAL80	13	171594	172901	W	Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding
3721	S000004514	ORF	Uncharacterized	YML050W	n.a.	13	173139	174074	W	Hypothetical protein
3723	S000004513	ORF	Verified	YML049C	RSE1	13	178305	174220	C	Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport
3725	S000004511	ORF	Verified	YML048W	GSF2	13	178426	179637	W	ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression
3727	S000004512	ORF	Dubious	YML047W-A	n.a.	13	179893	180258	W	Hypothetical protein
3729	S000004510	ORF	Verified	YML047C	PRM6	13	181075	180017	C	Pheromone-regulated protein, predicted to have 2 transmembrane segments; regulated by Ste12p during mating
3731	S000004509	ORF	Verified	YML046W	PRP39	13	181474	183363	W	U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats
3733	S000006585	tRNA	n.a.	tG(GCC)M	n.a.	13	183968	183898	C	tRNA-Gly
3744	S000004507	ORF	Verified	YML043C	RRN11	13	191767	190244	C	rDNA transcription factor CF component, which also contains Rrn6p and Rrn7p, which is required for rDNA transcription by RNA polymerase I; component of rDNA transcription factor
3746	S000004506	ORF	Verified	YML042W	CAT2	13	192788	194800	W	Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes
3748	S000004505	ORF	Verified	YML041C	VPS71	13	195755	194913	C	Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; required for vacuolar protein sorting
3750	S000006684	tRNA	n.a.	tP(UGG)M	SUF7	13	196170	196068	C	tRNA-Pro
3751	S000036019	intron	n.a.	n.a.	n.a.	13	196134	196104	C	n.a.
3763	S000004502	ORF	Verified	YML038C	YMD8	13	204103	202775	C	Putative nucleotide sugar transporter, has similarity to Vrg4p
3765	S000004501	ORF	Uncharacterized	YML037C	n.a.	13	205408	204386	C	Hypothetical protein
3767	S000004500	ORF	Uncharacterized	YML036W	n.a.	13	205642	206211	W	Hypothetical protein
3769	S000004498	ORF	Verified	YML035C	AMD1	13	208860	206428	C	AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools
3771	S000004497	ORF	Verified	YML034W	SRC1	13	209525	212155	W	Protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
3774	S000031571	intron	n.a.	n.a.	n.a.	13	211445	211570	W	n.a.
3775	S000004499	ORF	Dubious	YML034C-A	n.a.	13	209826	209428	C	Hypothetical protein
3777	S000004494	ORF	Verified	YML032C	RAD52	13	213930	212515	C	Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis
3779	S000004493	ORF	Verified	YML031W	NDC1	13	214189	216156	W	Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II
3781	S000028809	ORF	Dubious	YML031C-A	n.a.	13	214421	214086	C	Questionable ORF from MIPS
3783	S000004492	ORF	Uncharacterized	YML030W	n.a.	13	216435	216914	W	Hypothetical protein
3785	S000004491	ORF	Verified	YML029W	USA1	13	217362	219878	W	Protein that interacts in the two-hybrid system with the U1 snRNP-specific protein, Snp1p; may have a role in pre-mRNA splicing
3787	S000004490	ORF	Verified	YML028W	TSA1	13	220138	220728	W	Ubiquitous housekeeping thioredoxin peroxidase, reduces reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; mediates redox regulation of the nuclear localization of Yap1p; deletion results in mutator phenotype
3789	S000004489	ORF	Verified	YML027W	YOX1	13	221406	222563	W	Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate
3791	S000004488	ORF	Verified	YML026C	RPS18B	13	223828	222987	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins
3794	S000036755	intron	n.a.	n.a.	n.a.	13	223781	223381	C	n.a.
3795	S000004487	ORF	Verified	YML025C	YML6	13	225365	224406	C	Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins
3798	S000036691	intron	n.a.	n.a.	n.a.	13	225338	225240	C	n.a.
3799	S000004486	ORF	Verified	YML024W	RPS17A	13	225889	226697	W	Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein
3802	S000036661	intron	n.a.	n.a.	n.a.	13	225892	226289	W	n.a.
3803	S000004485	ORF	Uncharacterized	YML023C	n.a.	13	228664	226994	C	Protein required for cell viability
3805	S000004484	ORF	Verified	YML022W	APT1	13	228937	229500	W	Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis
3807	S000004483	ORF	Verified	YML021C	UNG1	13	230813	229734	C	Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus
3809	S000004482	ORF	Uncharacterized	YML020W	n.a.	13	231149	233143	W	Hypothetical protein
3811	S000004481	ORF	Verified	YML019W	OST6	13	233457	234455	W	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p
3813	S000004480	ORF	Uncharacterized	YML018C	n.a.	13	235952	234771	C	Hypothetical protein
3815	S000004479	ORF	Verified	YML017W	PSP2	13	236588	238731	W	Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing
3818	S000033402	intron	n.a.	n.a.	n.a.	13	236592	236953	W	n.a.
3819	S000004478	ORF	Verified	YML016C	PPZ1	13	241536	239458	C	Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
3821	S000004477	ORF	Verified	YML015C	TAF11	13	243029	241989	C	TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors
3823	S000004476	ORF	Verified	YML014W	TRM9	13	243225	244064	W	tRNA methyltransferase, catalyzes the esterification of modified uridine nucleotides in tRNAs, creating 5-methylcarbonylmethyluridine in tRNA(Arg3) and 5-methylcarbonylmethyl-2-thiouridine in tRNA(Glu); may have a role in stress response
3825	S000004475	ORF	Verified	YML013W	SEL1	13	244149	245903	W	UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, has a ubiquitin-associated (UBA) domain, interacts with ubiquitylated proteins in vivo, and is required for degradation of a ubiquitylated model substrate
3827	S000004474	ORF	Dubious	YML012C-A	n.a.	13	245914	245537	C	Hypothetical protein
3829	S000004473	ORF	Verified	YML012W	ERV25	13	246116	246751	W	Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport
3831	S000004472	ORF	Uncharacterized	YML011C	n.a.	13	247428	246895	C	Hypothetical protein
3833	S000004470	ORF	Verified	YML010W	SPT5	13	247677	250868	W	Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing
3835	S000004471	ORF	Dubious	YML009W-B	n.a.	13	250435	250911	W	Hypothetical protein
3837	S000004469	ORF	Dubious	YML009C-A	n.a.	13	251001	250675	C	Hypothetical protein
3839	S000004468	ORF	Verified	YML009C	MRPL39	13	251516	251304	C	Mitochondrial ribosomal protein of the large subunit
3841	S000004467	ORF	Verified	YML008C	ERG6	13	252990	251839	C	Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24
3843	S000007621	ORF	Uncharacterized	YML007C-A	n.a.	13	253272	253162	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
3845	S000004466	ORF	Verified	YML007W	YAP1	13	253848	255800	W	Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; mediates pleiotropic drug and metal resistance; localized to the nucleus in response to the presence of oxidants
3847	S000004465	ORF	Verified	YML006C	GIS4	13	258416	256092	C	CAAX box containing protein of unknown function, proposed to be involved in the RAS/cAMP signaling pathway
3849	S000006729	tRNA	n.a.	tS(AGA)M	n.a.	13	259239	259158	C	tRNA-Ser
3851	S000004464	ORF	Verified	YML005W	TRM12	13	260221	261609	W	S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; required for the wybutosine formation in the Phenylalanine-accepting tRNA.
3853	S000004463	ORF	Verified	YML004C	GLO1	13	262685	261705	C	Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress
3855	S000004462	ORF	Uncharacterized	YML003W	n.a.	13	263483	264355	W	Hypothetical protein
3857	S000004461	ORF	Uncharacterized	YML002W	n.a.	13	264541	266754	W	Hypothetical protein
3859	S000004460	ORF	Verified	YML001W	YPT7	13	267174	267800	W	Gtp-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, and for fusion of endosomes to vacuoles when expressed from high copy plasmid; GTP-binding protein, rab family
3865	S000004603	ORF	Verified	YMR001C	CDC5	13	271136	269019	C	Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate
3867	S000028691	ORF	Uncharacterized	YMR001C-A	n.a.	13	271577	271347	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
3869	S000004604	ORF	Uncharacterized	YMR002W	n.a.	13	272193	272663	W	Hypothetical protein
3871	S000004605	ORF	Uncharacterized	YMR003W	n.a.	13	273118	273714	W	Hypothetical protein
3873	S000004606	ORF	Verified	YMR004W	MVP1	13	274017	275552	W	Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole
3875	S000004607	ORF	Verified	YMR005W	TAF4	13	276045	277211	W	TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate
3877	S000004608	ORF	Verified	YMR006C	PLB2	13	279681	277561	C	Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine
3879	S000004609	ORF	Dubious	YMR007W	n.a.	13	279960	280340	W	Hypothetical protein
3881	S000004610	ORF	Verified	YMR008C	PLB1	13	282584	280590	C	Phospholipase B (lysophospholipase) involved in lipid metabolism, required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol
3883	S000004611	ORF	Verified	YMR009W	n.a.	13	284101	284640	W	Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1
3885	S000004612	ORF	Uncharacterized	YMR010W	n.a.	13	285099	286316	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
3887	S000004613	ORF	Verified	YMR011W	HXT2	13	288078	289703	W	High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
3890	S000006560	tRNA	n.a.	tE(UUC)M	n.a.	13	290800	290871	W	tRNA-Glu
3892	S000004614	ORF	Verified	YMR012W	CLU1	13	291133	294966	W	eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant
3894	S000028847	ORF	Dubious	YMR013C-A	n.a.	13	296619	296470	C	Identified by expression profiling and mass spectrometry
3896	S000004615	ORF	Verified	YMR013C	SEC59	13	296737	295178	C	Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation
3898	S000007312	snoRNA	n.a.	snR78	SNR78	13	297277	297362	W	Small nucleolar RNA; small nucleolar RNA
3900	S000007311	snoRNA	n.a.	snR77	SNR77	13	297505	297592	W	Small nucleolar RNA; small nucleolar RNA
3902	S000007310	snoRNA	n.a.	snR76	SNR76	13	297724	297832	W	Small nucleolar RNA; small nucleolar RNA
3904	S000007309	snoRNA	n.a.	snR75	SNR75	13	297917	298005	W	Small nucleolar RNA; small nucleolar RNA
3906	S000007308	snoRNA	n.a.	snR74	SNR74	13	298137	298224	W	Small nucleolar RNA; small nucleolar RNA
3908	S000007307	snoRNA	n.a.	snR73	SNR73	13	298306	298411	W	Small nucleolar RNA; small nucleolar RNA
3910	S000007622	ORF	Uncharacterized	YMR013W-A	n.a.	13	298310	298390	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
3912	S000007306	snoRNA	n.a.	snR72	SNR72	13	298553	298650	W	Small nucleolar RNA; small nucleolar RNA
3914	S000004616	ORF	Verified	YMR014W	BUD22	13	298867	300426	W	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
3916	S000004617	ORF	Verified	YMR015C	ERG5	13	302484	300868	C	C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs
3918	S000004618	ORF	Verified	YMR016C	SOK2	13	305592	303235	C	Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors
3920	S000004619	ORF	Verified	YMR017W	SPO20	13	307488	308681	W	Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog
3922	S000004620	ORF	Uncharacterized	YMR018W	n.a.	13	310207	311751	W	Hypothetical protein
3924	S000004621	ORF	Verified	YMR019W	STB4	13	312155	315004	W	Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins
3926	S000004622	ORF	Verified	YMR020W	FMS1	13	315376	316902	W	Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis
3928	S000004623	ORF	Verified	YMR021C	MAC1	13	318417	317164	C	Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport
3930	S000004624	ORF	Verified	YMR022W	QRI8	13	318679	319176	W	Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly
3932	S000004625	ORF	Verified	YMR023C	MSS1	13	321016	319436	C	Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3
3934	S000006518	tRNA	n.a.	tA(AGC)M1	n.a.	13	321218	321146	C	tRNA-Ala
3936	S000004626	ORF	Verified	YMR024W	MRPL3	13	321874	323046	W	Mitochondrial ribosomal protein of the large subunit
3938	S000004627	ORF	Verified	YMR025W	CSI1	13	323299	324186	W	Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
3940	S000004628	ORF	Verified	YMR026C	PEX12	13	325434	324235	C	RING-finger peroxisomal membrane peroxin that plays an essential role in peroxisome biogenesis and peroxisomal matrix protein import, forms translocation subcomplex with Pex2p and Pex10p
3942	S000004629	ORF	Uncharacterized	YMR027W	n.a.	13	325876	327288	W	High level expression reduced Ty3 Transposition
3944	S000004630	ORF	Verified	YMR028W	TAP42	13	327481	328581	W	Essential protein involved in the TOR signaling pathway; physically associates with the protein phosphatase 2A and the SIT4 protein phosphatase catalytic subunits
3946	S000004631	ORF	Verified	YMR029C	FAR8	13	330230	328659	C	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far9p, Far10p, and Far11p
3948	S000004632	ORF	Verified	YMR030W	RSF1	13	330792	331922	W	Protein required for respiratory growth; localized to both the nucleus and mitochondrion; mutant displays decreased transcription of specific nuclear and mitochondrial genes whose products are involved in respiratory growth
3950	S000004634	ORF	Dubious	YMR031W-A	n.a.	13	334708	335034	W	Hypothetical protein
3952	S000004633	ORF	Uncharacterized	YMR031C	n.a.	13	334742	332211	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
3954	S000004635	ORF	Verified	YMR032W	HOF1	13	335297	337306	W	Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p
3956	S000028574	ORF	Uncharacterized	YMR030W-A	n.a.	13	337312	337602	W	Identified by fungal homology and RT-PCR
3958	S000004636	ORF	Verified	YMR033W	ARP9	13	337787	339276	W	Actin-related protein involved in transcriptional regulation; subunit of the chromatin remodeling Snf/Swi complex
3961	S000035137	intron	n.a.	n.a.	n.a.	13	337817	337902	W	n.a.
3962	S000004637	ORF	Uncharacterized	YMR034C	n.a.	13	340721	339417	C	Hypothetical protein
3964	S000004638	ORF	Verified	YMR035W	IMP2	13	341141	341674	W	Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p
3966	S000004639	ORF	Verified	YMR036C	MIH1	13	343519	341855	C	Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25
3968	S000004640	ORF	Verified	YMR037C	MSN2	13	346516	344402	C	Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression
3970	S000004641	ORF	Verified	YMR038C	CCS1	13	348259	347510	C	Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation
3972	S000004642	ORF	Verified	YMR039C	SUB1	13	349521	348643	C	Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations
3974	S000004643	ORF	Uncharacterized	YMR040W	n.a.	13	350380	350862	W	Endoplasmic reticulum transmembrane protein, homolog of human BAP31 protein
3976	S000004644	ORF	Uncharacterized	YMR041C	n.a.	13	351972	350965	C	Hypothetical protein
3978	S000006568	tRNA	n.a.	tF(GAA)M	n.a.	13	352279	352369	W	tRNA-Phe
3979	S000035417	intron	n.a.	n.a.	n.a.	13	352316	352333	W	n.a.
3982	S000004645	ORF	Verified	YMR042W	ARG80	13	352602	353135	W	Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p
3984	S000004646	ORF	Verified	YMR043W	MCM1	13	353870	354730	W	Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes
3986	S000004647	ORF	Verified	YMR044W	IOC4	13	355383	356810	W	Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PWWP motif
3995	S000007248	ORF	Dubious	YMR046W-A	n.a.	13	362701	362829	W	Similar to probable membrane protein YLR334C and ORF YOL106W
3999	S000006599	tRNA	n.a.	tH(GUG)M	n.a.	13	363063	363134	W	tRNA-His
4001	S000004650	ORF	Verified	YMR047C	NUP116	13	366704	363363	C	Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p
4003	S000004651	ORF	Verified	YMR048W	CSM3	13	366980	367933	W	Protein required for accurate chromosome segregation during meiosis
4005	S000004652	ORF	Verified	YMR049C	ERB1	13	370516	368093	C	Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1
4007	S000006763	tRNA	n.a.	tV(AAC)M1	n.a.	13	372517	372444	C	tRNA-Val
4020	S000006775	tRNA	n.a.	tW(CCA)M	n.a.	13	379407	379302	C	tRNA-Trp
4021	S000034112	intron	n.a.	n.a.	n.a.	13	379371	379338	C	n.a.
4024	S000004656	ORF	Verified	YMR052W	FAR3	13	379585	380199	W	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p
4026	S000004655	ORF	Dubious	YMR052C-A	n.a.	13	380433	380068	C	Hypothetical protein
4028	S000004657	ORF	Verified	YMR053C	STB2	13	382897	380345	C	Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p
4030	S000004658	ORF	Verified	YMR054W	STV1	13	383302	385974	W	Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole
4032	S000004659	ORF	Verified	YMR055C	BUB2	13	387020	386100	C	Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage
4034	S000004660	ORF	Verified	YMR056C	AAC1	13	388243	387314	C	Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator
4036	S000004661	ORF	Dubious	YMR057C	n.a.	13	388729	388358	C	Hypothetical protein
4038	S000004662	ORF	Verified	YMR058W	FET3	13	388821	390731	W	Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases
4040	S000004663	ORF	Verified	YMR059W	SEN15	13	391038	391484	W	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p
4042	S000004664	ORF	Verified	YMR060C	SAM37	13	392514	391531	C	Component of the mitochondrial outer membrane sorting and assembly machinery (SAM) complex; required for the sorting of some proteins to the outer membrane after import by the TOM complex
4044	S000004665	ORF	Verified	YMR061W	RNA14	13	392754	394787	W	Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex
4046	S000004666	ORF	Verified	YMR062C	ECM40	13	396378	395053	C	Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine
4048	S000004667	ORF	Verified	YMR063W	RIM9	13	397076	397795	W	Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalI; putative membrane protein
4050	S000004668	ORF	Verified	YMR064W	AEP1	13	397902	399458	W	Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase
4052	S000004669	ORF	Verified	YMR065W	KAR5	13	399701	401215	W	Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone
4054	S000004670	ORF	Uncharacterized	YMR066W	n.a.	13	401540	404236	W	Mitochondrial protein of unknown function
4056	S000004671	ORF	Uncharacterized	YMR067C	UBX4	13	405572	404322	C	UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
4058	S000004672	ORF	Verified	YMR068W	AVO2	13	406303	407583	W	Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
4060	S000004673	ORF	Verified	YMR069W	NAT4	13	407708	408565	W	N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A
4062	S000004674	ORF	Verified	YMR070W	MOT3	13	409153	410625	W	Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes
4064	S000004675	ORF	Uncharacterized	YMR071C	n.a.	13	411264	410761	C	Tlg2-Vesicle Protein of 18 kDa, integral membrane vesicle protein
4066	S000004676	ORF	Verified	YMR072W	ABF2	13	411568	412119	W	Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation
4068	S000004677	ORF	Uncharacterized	YMR073C	n.a.	13	412872	412267	C	Hypothetical protein
4070	S000004678	ORF	Uncharacterized	YMR074C	n.a.	13	413472	413035	C	Hypothetical protein
4072	S000004680	ORF	Uncharacterized	YMR075W	n.a.	13	413981	416035	W	Nuclear protein of unknown function
4074	S000004679	ORF	Dubious	YMR075C-A	n.a.	13	416052	415687	C	Hypothetical protein
4076	S000004681	ORF	Verified	YMR076C	PDS5	13	420028	416195	C	Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold
4078	S000006764	tRNA	n.a.	tV(AAC)M2	n.a.	13	420660	420587	C	tRNA-Val
4080	S000004682	ORF	Verified	YMR077C	VPS20	13	422148	421483	C	Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes
4082	S000004683	ORF	Verified	YMR078C	CTF18	13	424727	422502	C	Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint
4084	S000004684	ORF	Verified	YMR079W	SEC14	13	424988	426058	W	Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate regulation of PtdIns and PtdCho metabolism, products of which are regulators in Golgi to plasma membrane transport; functionally homologous to mammalian PITPs
4087	S000036085	intron	n.a.	n.a.	n.a.	13	424997	425152	W	n.a.
4088	S000004685	ORF	Verified	YMR080C	NAM7	13	429626	426711	C	ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons
4090	S000004686	ORF	Verified	YMR081C	ISF1	13	431094	430078	C	Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant
4092	S000004687	ORF	Dubious	YMR082C	n.a.	13	432124	431768	C	Hypothetical protein
4094	S000004688	ORF	Verified	YMR083W	ADH3	13	434787	435914	W	Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production
4096	S000004689	ORF	Uncharacterized	YMR084W	n.a.	13	436627	437415	W	Hypothetical protein
4098	S000004690	ORF	Uncharacterized	YMR085W	n.a.	13	437490	438788	W	Hypothetical protein
4100	S000004692	ORF	Uncharacterized	YMR086W	n.a.	13	439207	442089	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
4102	S000004691	ORF	Dubious	YMR086C-A	n.a.	13	442363	442025	C	Hypothetical protein
4104	S000004693	ORF	Verified	YMR087W	n.a.	13	442526	443380	W	Putative ADP-ribose-1''-monophosphatase that converts ADP-ribose-1''-monophosphate to ADP-ribose; may have a role in tRNA splicing; contains an A1pp domain
4106	S000004694	ORF	Verified	YMR088C	VBA1	13	445101	443413	C	Permease of basic amino acids in the vacuolar membrane
4108	S000004695	ORF	Verified	YMR089C	YTA12	13	448085	445608	C	Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes
4110	S000004696	ORF	Uncharacterized	YMR090W	n.a.	13	449244	449927	W	Hypothetical protein
4112	S000004697	ORF	Verified	YMR091C	NPL6	13	451364	450057	C	Nuclear protein that may have a role in nuclear protein import
4114	S000004698	ORF	Verified	YMR092C	AIP1	13	453478	451631	C	Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats
4116	S000004699	ORF	Verified	YMR093W	UTP15	13	454014	455555	W	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
4118	S000004700	ORF	Verified	YMR094W	CTF13	13	455824	457260	W	Subunit of the CBF3 complex, which binds to the CDE III element of centromeres, bending the DNA upon binding, and may be involved in sister chromatid cohesion during mitosis
4120	S000004701	ORF	Verified	YMR095C	SNO1	13	457958	457284	C	Protein of unconfirmed function, involved in pyridoxine metabolism; expression is induced during stationary phase; forms a putative glutamine amidotransferase complex with Snz1p, with Sno1p serving as the glutaminase
4122	S000004702	ORF	Verified	YMR096W	SNZ1	13	458407	459300	W	Protein involved in vitamin B6 biosynthesis; member of a stationary phase-induced gene family; coregulated with SNO1; interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins
4124	S000004703	ORF	Verified	YMR097C	MTG1	13	460526	459423	C	Peripheral GTPase of the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals
4126	S000004704	ORF	Uncharacterized	YMR098C	n.a.	13	462608	460770	C	Hypothetical protein
4129	S000006543	tRNA	n.a.	tD(GUC)M	n.a.	13	463553	463624	W	tRNA-Asp
4131	S000004705	ORF	Uncharacterized	YMR099C	n.a.	13	464826	463933	C	Hypothetical protein
4133	S000004706	ORF	Verified	YMR100W	MUB1	13	466299	468161	W	Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene
4135	S000004707	ORF	Verified	YMR101C	SRT1	13	469475	468444	C	Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase
4137	S000004708	ORF	Uncharacterized	YMR102C	n.a.	13	472351	469847	C	Protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
4139	S000004709	ORF	Dubious	YMR103C	n.a.	13	473263	472901	C	Hypothetical protein
4141	S000004710	ORF	Verified	YMR104C	YPK2	13	475452	473419	C	Protein kinase with similarityto serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK
4143	S000004711	ORF	Verified	YMR105C	PGM2	13	477605	475896	C	Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase
4145	S000028692	ORF	Uncharacterized	YMR105W-A	n.a.	13	478063	478257	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4147	S000004712	ORF	Verified	YMR106C	YKU80	13	480189	478300	C	Forms heterodimer with Yku70p known as Ku, binds chromosome ends and is involved in maintaining normal telomere length and structure, in addition to participating in the formation of silent chromatin at telomere-proximal genes
4149	S000006627	tRNA	n.a.	tK(CUU)M	n.a.	13	480692	480620	C	tRNA-Lys
4153	S000004713	ORF	Verified	YMR107W	SPG4	13	483013	483360	W	Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
4155	S000004714	ORF	Verified	YMR108W	ILV2	13	484083	486146	W	Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control
4157	S000004715	ORF	Verified	YMR109W	MYO5	13	486586	490245	W	One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization
4159	S000004716	ORF	Uncharacterized	YMR110C	n.a.	13	491991	490393	C	Hypothetical protein
4161	S000004717	ORF	Uncharacterized	YMR111C	n.a.	13	493791	492403	C	Hypothetical protein
4163	S000004718	ORF	Verified	YMR112C	MED11	13	494494	494099	C	14 Kd mediator subunit of RNA polymerase II holoenzyme
4165	S000004719	ORF	Verified	YMR113W	FOL3	13	494998	496281	W	Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis
4167	S000004720	ORF	Uncharacterized	YMR114C	n.a.	13	497448	496342	C	Hypothetical protein
4169	S000004721	ORF	Uncharacterized	YMR115W	n.a.	13	497703	499208	W	The authentic, non-tagged protein was localized to the mitochondria
4171	S000007501	snoRNA	n.a.	snR24	SNR24	13	500071	499983	C	guides 2'-O-methylation on large subunit rRNA at C1437, A1449, and G1450; small nucleolar RNA U24
4173	S000004722	ORF	Verified	YMR116C	ASC1	13	500687	499455	C	WD repeat protein (G-beta like protein) involved in translation regulation; required for repression of Gcn4p activity in the absence of amino-acid starvation; core component of the ribosome; ortholog of mammalian RACK1
4176	S000031295	intron	n.a.	n.a.	n.a.	13	500150	499878	C	n.a.
4177	S000004723	ORF	Verified	YMR117C	SPC24	13	501890	501249	C	Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
4179	S000004724	ORF	Uncharacterized	YMR118C	n.a.	13	502733	502143	C	Hypothetical protein
4184	S000006644	tRNA	n.a.	tL(CAA)M	n.a.	13	504894	505007	W	tRNA-Leu
4185	S000033800	intron	n.a.	n.a.	n.a.	13	504932	504963	W	n.a.
4188	S000004725	ORF	Verified	YMR119W	ASI1	13	505332	507206	W	Putative integral membrane E3 ubiquitin ligase; genetic interactions suggest a role in negative regulation of amino acid uptake
4190	S000004726	ORF	Dubious	YMR119W-A	n.a.	13	506995	507369	W	Hypothetical protein
4192	S000004727	ORF	Verified	YMR120C	ADE17	13	509279	507501	C	Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine
4194	S000004728	ORF	Verified	YMR121C	RPL15B	13	510347	509733	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA
4196	S000004729	ORF	Dubious	YMR122C	n.a.	13	511074	510700	C	Hypothetical protein
4198	S000007524	ORF	Uncharacterized	YMR122W-A	n.a.	13	511314	511568	W	Hypothetical protein
4200	S000004730	ORF	Verified	YMR123W	PKR1	13	513592	513960	W	Protein of unknown function; overproduction confers resistance to Pichia farinosa killer toxin
4202	S000004731	ORF	Uncharacterized	YMR124W	n.a.	13	514455	517286	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck
4204	S000004732	ORF	Verified	YMR125W	STO1	13	517538	520445	W	Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry poly(A)+ mRNA from the nucleus to the cytoplasm; also involved in mRNA degradation in the nucleus; orthologous to mammalian CBP80
4207	S000035484	intron	n.a.	n.a.	n.a.	13	517563	517884	W	n.a.
4208	S000004733	ORF	Uncharacterized	YMR126C	n.a.	13	521788	520760	C	Protein of unknown function, deletion causes sensitivity to thermal stress
4210	S000004734	ORF	Verified	YMR127C	SAS2	13	523344	522328	C	Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which  acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family
4212	S000004735	ORF	Verified	YMR128W	ECM16	13	523695	527498	W	Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis
4214	S000004736	ORF	Verified	YMR129W	POM152	13	527803	531816	W	Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase;
4216	S000004737	ORF	Uncharacterized	YMR130W	n.a.	13	532118	533026	W	Hypothetical protein
4218	S000004738	ORF	Verified	YMR131C	RRB1	13	534697	533162	C	Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p
4220	S000004739	ORF	Uncharacterized	YMR132C	JLP2	13	535569	534943	C	Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)
4222	S000004740	ORF	Verified	YMR133W	REC114	13	536206	537608	W	Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division
4225	S000037487	intron	n.a.	n.a.	n.a.	13	537448	537563	W	n.a.
4226	S000004741	ORF	Uncharacterized	YMR134W	n.a.	13	537837	538550	W	Protein required for cell viability
4228	S000004743	ORF	Dubious	YMR135W-A	n.a.	13	539910	540443	W	Hypothetical protein
4230	S000004742	ORF	Verified	YMR135C	GID8	13	540055	538688	C	Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p
4232	S000004744	ORF	Verified	YMR136W	GAT2	13	541198	542880	W	Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine
4234	S000004745	ORF	Verified	YMR137C	PSO2	13	544962	542977	C	Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation
4236	S000004746	ORF	Verified	YMR138W	CIN4	13	545154	545729	W	GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
4238	S000004747	ORF	Verified	YMR139W	RIM11	13	546124	547236	W	Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta
4240	S000004748	ORF	Verified	YMR140W	SIP5	13	547713	549182	W	Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase
4242	S000004749	ORF	Dubious	YMR141C	n.a.	13	550043	549735	C	Hypothetical protein
4244	S000028575	ORF	Dubious	YMR141W-A	n.a.	13	550910	551134	W	Identified by fungal homology and RT-PCR
4246	S000004750	ORF	Verified	YMR142C	RPL13B	13	551206	550205	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential for viability; has similarity to rat L13 ribosomal protein
4249	S000032640	intron	n.a.	n.a.	n.a.	13	551202	550801	C	n.a.
4250	S000004751	ORF	Verified	YMR143W	RPS16A	13	551927	552902	W	Protein component of the small (40S) ribosomal subunit; identical to Rps16Bp and has similarity to E. coli S9 and rat S16 ribosomal proteins
4253	S000032781	intron	n.a.	n.a.	n.a.	13	551951	552494	W	n.a.
4254	S000004752	ORF	Uncharacterized	YMR144W	n.a.	13	553361	554389	W	Hypothetical protein
4256	S000004753	ORF	Verified	YMR145C	NDE1	13	556474	554792	C	Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain
4258	S000004754	ORF	Verified	YMR146C	TIF34	13	558523	557480	C	Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation
4260	S000004755	ORF	Uncharacterized	YMR147W	n.a.	13	559198	559869	W	Hypothetical protein
4262	S000004756	ORF	Uncharacterized	YMR148W	n.a.	13	560365	560811	W	Hypothetical protein
4264	S000004757	ORF	Verified	YMR149W	SWP1	13	560995	561855	W	Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum
4266	S000004759	ORF	Dubious	YMR151W	YIM2	13	562505	562942	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 5% of ORF overlaps the verified gene IMP1
4268	S000004758	ORF	Verified	YMR150C	IMP1	13	562527	561955	C	Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p
4270	S000004760	ORF	Verified	YMR152W	YIM1	13	563095	564192	W	Mitochondrial inner membrane protease, similar to E. coli leader peptidase
4272	S000004762	ORF	Verified	YMR153W	NUP53	13	564434	565861	W	Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex
4274	S000004761	ORF	Dubious	YMR153C-A	n.a.	13	565908	565573	C	Hypothetical protein
4276	S000004763	ORF	Verified	YMR154C	RIM13	13	568181	565998	C	Calpain-like protease involved in proteolytic activation of Ri0m101p in response to alkaline pH; has similarity to A. nidulans palB
4278	S000004764	ORF	Uncharacterized	YMR155W	n.a.	13	568550	570193	W	Hypothetical protein
4280	S000004765	ORF	Verified	YMR156C	TPP1	13	571015	570299	C	DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily
4282	S000004766	ORF	Uncharacterized	YMR157C	n.a.	13	572043	571276	C	The authentic, non-tagged protein was localized to the mitochondria
4284	S000004767	ORF	Verified	YMR158W	MRPS8	13	572247	572714	W	Mitochondrial ribosomal protein of the small subunit
4286	S000006664	tRNA	n.a.	tM(CAU)M	EMT4	13	572954	572882	C	tRNA that accepts methionine; functions in translational elongation but not translational initiation
4288	S000007249	ORF	Uncharacterized	YMR158C-A	n.a.	13	573330	573193	C	Similar to probable membrane protein YDR340W and to yeast CYC1/CYP3 transcription activator
4291	S000004768	ORF	Dubious	YMR158W-B	n.a.	13	574470	574790	W	Hypothetical protein
4293	S000004769	ORF	Verified	YMR159C	ATG16	13	574927	574475	C	Protein that interacts with the Atg12p-Atg5p conjugate during formation of the pre-autophagosomal structure; essential for autophagy
4295	S000004770	ORF	Uncharacterized	YMR160W	n.a.	13	575065	577515	W	Hypothetical protein
4297	S000004771	ORF	Verified	YMR161W	HLJ1	13	577717	578391	W	Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ
4299	S000004772	ORF	Verified	YMR162C	DNF3	13	583920	578950	C	Non-essential P-type ATPase that is a potential aminophospholipid translocase, localizes to the trans-Golgi, likely involved in protein transport
4301	S000004773	ORF	Uncharacterized	YMR163C	n.a.	13	586387	584270	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
4303	S000006765	tRNA	n.a.	tV(AAC)M3	n.a.	13	586708	586635	C	tRNA-Val
4305	S000004774	ORF	Verified	YMR164C	MSS11	13	589549	587273	C	Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals
4307	S000004775	ORF	Verified	YMR165C	SMP2	13	592627	590039	C	Protein of unknown function involved in respiration and plasmid maintenance; proposed to be involved in cell wall integrity
4309	S000004776	ORF	Uncharacterized	YMR166C	n.a.	13	594472	593366	C	Hypothetical protein
4311	S000004777	ORF	Verified	YMR167W	MLH1	13	594885	597194	W	Protein required for mismatch repair in mitosis and meiosis, postmeiotic segregation, and spore viability; forms a complex with Pms1p and Msh2p to repair mismatched DNA; human homolog is associated with hereditary non-polyposis colon cancer
4313	S000004778	ORF	Verified	YMR168C	CEP3	13	599157	597331	C	Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain
4315	S000004779	ORF	Verified	YMR169C	ALD3	13	600871	599351	C	Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose
4317	S000004780	ORF	Verified	YMR170C	ALD2	13	603081	601561	C	Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p
4319	S000004781	ORF	Uncharacterized	YMR171C	n.a.	13	605519	603867	C	Endosomal protein of unknown function, mRNA is targeted to the bud via the mRNA transport system involving She2p
4321	S000004783	ORF	Verified	YMR172W	HOT1	13	605980	608139	W	Transcription factor required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p
4323	S000004782	ORF	Dubious	YMR172C-A	n.a.	13	608210	607827	C	Hypothetical protein
4325	S000004784	ORF	Verified	YMR173W	DDR48	13	608688	609980	W	DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS
4327	S000004785	ORF	Dubious	YMR173W-A	n.a.	13	608896	610080	W	Hypothetical protein
4329	S000004786	ORF	Verified	YMR174C	PAI3	13	610364	610158	C	Cytoplasmic proteinase A inhibitor, dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact
4331	S000004787	ORF	Verified	YMR175W	SIP18	13	611015	611254	W	Protein of unknown function whose expression is induced by osmotic stress
4333	S000028848	ORF	Uncharacterized	YMR175W-A	n.a.	13	611313	611507	W	Identified by expression profiling and mass spectrometry
4335	S000004788	ORF	Verified	YMR176W	ECM5	13	611739	615974	W	Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks
4337	S000004789	ORF	Verified	YMR177W	MMT1	13	616565	618097	W	Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p
4339	S000004790	ORF	Uncharacterized	YMR178W	n.a.	13	618478	619302	W	Hypothetical protein
4341	S000004791	ORF	Verified	YMR179W	SPT21	13	619857	622133	W	Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p
4343	S000004792	ORF	Verified	YMR180C	CTL1	13	623212	622250	C	RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm
4345	S000004793	ORF	Uncharacterized	YMR181C	n.a.	13	624079	623615	C	Protein of unknown function; open reading frame may be part of a bicistronic transcript with RGM1
4347	S000004794	ORF	Verified	YMR182C	RGM1	13	625166	624531	C	Putative transcriptional repressor with proline-rich zinc fingers; overproduction impairs cell growth
4349	S000028693	ORF	Uncharacterized	YMR182W-A	n.a.	13	625810	625896	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4351	S000028468	snoRNA	n.a.	snR83	SNR83	13	626348	626653	W	H/ACA snoRNA; guides pseudouridylation of small subunit rRNA at position 1289
4353	S000004795	ORF	Verified	YMR183C	SSO2	13	627807	626920	C	Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p
4355	S000004796	ORF	Uncharacterized	YMR184W	n.a.	13	628188	628784	W	Hypothetical protein
4357	S000004797	ORF	Uncharacterized	YMR185W	n.a.	13	629024	631969	W	Protein required for cell viability
4359	S000004798	ORF	Verified	YMR186W	HSC82	13	632354	634471	W	Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels that HSP82 and induced 2-3 fold by heat shock
4361	S000004799	ORF	Uncharacterized	YMR187C	n.a.	13	635983	634688	C	Hypothetical protein
4363	S000004800	ORF	Verified	YMR188C	MRPS17	13	637003	636290	C	Mitochondrial ribosomal protein of the small subunit
4365	S000004801	ORF	Verified	YMR189W	GCV2	13	637499	640603	W	P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm
4367	S000004802	ORF	Verified	YMR190C	SGS1	13	645257	640914	C	Nucleolar DNA helicase of the RecQ family, involved in maintenance of genome integrity; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes
4369	S000004803	ORF	Verified	YMR191W	SPG5	13	645655	646776	W	Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
4371	S000004804	ORF	Verified	YMR192W	GYL1	13	647117	649279	W	Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p
4373	S000004806	ORF	Verified	YMR193W	MRPL24	13	650035	650811	W	Mitochondrial ribosomal protein of the large subunit
4375	S000004807	ORF	Verified	YMR194W	RPL36A	13	651144	651909	W	N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Bp and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA
4378	S000035871	intron	n.a.	n.a.	n.a.	13	651160	651622	W	n.a.
4379	S000004805	ORF	Dubious	YMR193C-A	n.a.	13	651457	651071	C	Hypothetical protein
4381	S000007293	snoRNA	n.a.	snR11	SNR11	13	652274	652531	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2415
4383	S000028514	ORF	Uncharacterized	YMR194C-B	n.a.	13	652886	652593	C	Identified based on homology to <i>Ashbya gossypii</i>
4386	S000030282	intron	n.a.	n.a.	n.a.	13	652846	652775	C	n.a.
4387	S000007250	ORF	Dubious	YMR194C-A	n.a.	13	653135	652911	C	Hypothetical protein
4389	S000004808	ORF	Uncharacterized	YMR195W	ICY1	13	654033	654416	W	Protein that interacts with the cytoskeleton and is involved in chromatin organization and nuclear transport, interacts genetically with TCP1 and ICY2, required for viability in rich media of cells lacking mitochondrial DNA
4391	S000004809	ORF	Uncharacterized	YMR196W	n.a.	13	655075	658341	W	Hypothetical protein
4393	S000004810	ORF	Verified	YMR197C	VTI1	13	659197	658544	C	Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways
4395	S000004811	ORF	Verified	YMR198W	CIK1	13	659744	661528	W	CIK1 is important for proper organiziation of microtubule arrays and establishment of a spindle; is essential for karyogamy; and expression is regulated by KAR4 and mating; spindle pole body associated protein
4397	S000004812	ORF	Verified	YMR199W	CLN1	13	662643	664283	W	G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
4399	S000004813	ORF	Verified	YMR200W	ROT1	13	664751	665521	W	Protein that may be involved in cell wall function; mutations in rot1 cause cell wall defects, suppress tor2 mutations, and are synthetically lethal with rot2 mutations
4401	S000004814	ORF	Verified	YMR201C	RAD14	13	667043	665844	C	Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein
4404	S000035531	intron	n.a.	n.a.	n.a.	13	667016	666933	C	n.a.
4405	S000004815	ORF	Verified	YMR202W	ERG2	13	667536	668204	W	C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis
4407	S000004816	ORF	Verified	YMR203W	TOM40	13	668491	669654	W	Essential component of the preprotein translocase of the mitochondrial outer membrane (TOM complex) in which it constitutes the core element of the protein conducting pore
4409	S000004817	ORF	Verified	YMR204C	INP1	13	671324	670062	C	Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance
4411	S000004818	ORF	Verified	YMR205C	PFK2	13	674765	671886	C	Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
4413	S000004819	ORF	Uncharacterized	YMR206W	n.a.	13	675895	676836	W	Hypothetical protein
4415	S000004820	ORF	Verified	YMR207C	HFA1	13	683563	677192	C	Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondrial fatty acid biosynthesis
4417	S000004821	ORF	Verified	YMR208W	ERG12	13	684466	685797	W	Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
4419	S000004822	ORF	Uncharacterized	YMR209C	n.a.	13	687283	685910	C	Hypothetical protein
4421	S000004823	ORF	Uncharacterized	YMR210W	n.a.	13	687515	688864	W	Hypothetical protein
4423	S000004824	ORF	Verified	YMR211W	DML1	13	689082	690509	W	Essential protein involved in mtDNA inheritance, may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family
4425	S000004825	ORF	Verified	YMR212C	EFR3	13	693042	690694	C	Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
4427	S000004826	ORF	Verified	YMR213W	CEF1	13	693380	695152	W	Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p
4429	S000004827	ORF	Verified	YMR214W	SCJ1	13	695349	696482	W	One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins
4431	S000004828	ORF	Verified	YMR215W	GAS3	13	696795	698369	W	Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
4433	S000004829	ORF	Verified	YMR216C	SKY1	13	701038	698810	C	SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1
4435	S000004830	ORF	Verified	YMR217W	GUA1	13	701789	703366	W	GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
4437	S000004831	ORF	Verified	YMR218C	TRS130	13	706886	703578	C	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in ER to Golgi membrane traffic; mutation activates transcription of OCH1
4439	S000004832	ORF	Verified	YMR219W	ESC1	13	707132	712108	W	Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p
4441	S000004833	ORF	Verified	YMR220W	ERG8	13	712315	713670	W	Phosphomevalonate kinase, an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
4443	S000004834	ORF	Uncharacterized	YMR221C	n.a.	13	715444	713930	C	The authentic, non-tagged protein was localized to the mitochondria
4445	S000004835	ORF	Verified	YMR222C	FSH2	13	716308	715637	C	Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh1p and Fsh3p
4447	S000004836	ORF	Verified	YMR223W	UBP8	13	716714	718129	W	Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B
4449	S000004837	ORF	Verified	YMR224C	MRE11	13	720652	718574	C	Subunit of a complex with Rad50p and Xrs2p (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for RMX function; widely conserved
4451	S000004838	ORF	Verified	YMR225C	MRPL44	13	721402	720959	C	Mitochondrial ribosomal protein of the large subunit
4454	S000036821	intron	n.a.	n.a.	n.a.	13	721344	721198	C	n.a.
4455	S000004839	ORF	Uncharacterized	YMR226C	n.a.	13	722395	721592	C	NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids
4457	S000004840	ORF	Verified	YMR227C	TAF7	13	724384	722612	C	TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation
4459	S000004841	ORF	Verified	YMR228W	MTF1	13	724625	725650	W	Mitochondrial RNA polymerase sigma-like specificity factor required for promoter recognition, interacts with mitochondrial core polymerase Rpo41p, imported into mitochondria via a novel process requiring most of the Mtf1p sequence
4461	S000004842	ORF	Verified	YMR229C	RRP5	13	731122	725933	C	Protein required for the synthesis of both 18S and 5.8S rRNA; C-terminal region is crucial for the formation of 18S rRNA and N-terminal region is required for the 5.8S rRNA; component of small ribosomal subunit (SSU) processosome
4463	S000004843	ORF	Verified	YMR230W	RPS10B	13	732413	733140	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Ap and has similarity to rat ribosomal protein S10
4466	S000030775	intron	n.a.	n.a.	n.a.	13	732465	732874	W	n.a.
4467	S000028576	ORF	Uncharacterized	YMR230W-A	n.a.	13	733267	733455	W	Identified by fungal homology and RT-PCR
4469	S000004844	ORF	Verified	YMR231W	PEP5	13	733544	736633	W	Peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; forms complex with Pep3p that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, also interacts with Pep7p
4471	S000004845	ORF	Verified	YMR232W	FUS2	13	736925	738958	W	Cytoplasmic protein localized to the shmoo tip; required for the alignment of parental nuclei before nuclear fusion during mating
4473	S000004846	ORF	Uncharacterized	YMR233W	n.a.	13	739184	739864	W	Interacts with Top1p in 2-hybrid assay.
4475	S000004847	ORF	Verified	YMR234W	RNH1	13	740265	741311	W	Ribonuclease H1, removes RNA primers during Okazaki fragment synthesis; degrades RNA attached to the 5'-end of a DNA strand
4477	S000004848	ORF	Verified	YMR235C	RNA1	13	742734	741511	C	GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport
4479	S000004849	ORF	Verified	YMR236W	TAF9	13	742970	743443	W	Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3
4481	S000004850	ORF	Uncharacterized	YMR237W	n.a.	13	743748	745922	W	Protein that colocalizes with clathrin-coated vesicles; involved in transport at the trans-Golgi
4483	S000004851	ORF	Verified	YMR238W	DFG5	13	746352	747728	W	Mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis, involved in filamentous growth, homologous to Dcw1p
4485	S000006717	tRNA	n.a.	tR(UCU)M1	n.a.	13	747962	747891	C	tRNA-Arg
4487	S000004852	ORF	Verified	YMR239C	RNT1	13	749676	748261	C	RNAase III; cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end
4489	S000004853	ORF	Verified	YMR240C	CUS1	13	751239	749929	C	Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p
4491	S000004854	ORF	Verified	YMR241W	YHM2	13	751960	752904	W	Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family
4493	S000004855	ORF	Verified	YMR242C	RPL20A	13	754196	753224	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein
4496	S000035253	intron	n.a.	n.a.	n.a.	13	754177	753742	C	n.a.
4497	S000028694	ORF	Uncharacterized	YMR242W-A	n.a.	13	754296	754385	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4499	S000004856	ORF	Verified	YMR243C	ZRC1	13	756165	754837	C	Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; also has a role in resistance to zinc shock resulting from a sudden influx of zinc into the cytoplasm
4501	S000004858	ORF	Uncharacterized	YMR244W	n.a.	13	757249	758316	W	Hypothetical protein
4503	S000004859	ORF	Dubious	YMR245W	n.a.	13	758562	759182	W	Hypothetical protein
4505	S000004857	ORF	Uncharacterized	YMR244C-A	n.a.	13	758830	758516	C	Hypothetical protein
4507	S000004860	ORF	Verified	YMR246W	FAA4	13	759806	761890	W	Long chain fatty acyl-CoA synthetase
4509	S000004861	ORF	Uncharacterized	YMR247C	n.a.	13	768038	763350	C	Hypothetical protein
4511	S000006519	tRNA	n.a.	tA(AGC)M2	n.a.	13	768440	768368	C	tRNA-Ala
4514	S000028849	ORF	Uncharacterized	YMR247W-A	n.a.	13	769282	769425	W	Identified by expression profiling and mass spectrometry
4516	S000004862	ORF	Verified	YMR250W	GAD1	13	770800	772557	W	Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress
4518	S000004863	ORF	Uncharacterized	YMR251W	n.a.	13	772914	774014	W	Omega class glutathione transferase
4520	S000004864	ORF	Verified	YMR251W-A	HOR7	13	774751	774930	W	Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor
4522	S000004865	ORF	Uncharacterized	YMR252C	n.a.	13	775718	775314	C	Hypothetical protein
4524	S000004866	ORF	Uncharacterized	YMR253C	n.a.	13	777189	775945	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
4526	S000004867	ORF	Dubious	YMR254C	n.a.	13	777922	777614	C	Hypothetical protein
4528	S000004868	ORF	Verified	YMR255W	GFD1	13	778000	778566	W	Coiled-coiled protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation
4530	S000004869	ORF	Verified	YMR256C	COX7	13	779126	778944	C	Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
4532	S000004870	ORF	Verified	YMR257C	PET111	13	782030	779628	C	Specific translational activator for the COX2 mRNA, located in the mitochondrial inner membrane
4534	S000004871	ORF	Uncharacterized	YMR258C	n.a.	13	784280	782619	C	Hypothetical protein
4536	S000004872	ORF	Uncharacterized	YMR259C	n.a.	13	788882	784620	C	Hypothetical protein
4538	S000004873	ORF	Verified	YMR260C	TIF11	13	789838	789377	C	Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3
4540	S000004874	ORF	Verified	YMR261C	TPS3	13	793368	790204	C	Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
4542	S000004875	ORF	Uncharacterized	YMR262W	n.a.	13	793725	794666	W	Hypothetical protein
4544	S000004876	ORF	Verified	YMR263W	SAP30	13	794918	795523	W	Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci
4546	S000004877	ORF	Verified	YMR264W	CUE1	13	795804	796415	W	Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination
4548	S000004878	ORF	Uncharacterized	YMR265C	n.a.	13	797924	796539	C	Hypothetical protein
4550	S000004879	ORF	Uncharacterized	YMR266W	n.a.	13	798517	801378	W	Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant
4552	S000004880	ORF	Verified	YMR267W	PPA2	13	801771	802703	W	Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate
4554	S000004881	ORF	Verified	YMR268C	PRP24	13	804221	802887	C	Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling
4556	S000004882	ORF	Uncharacterized	YMR269W	n.a.	13	804455	805090	W	Nucleolar protein of unknown function
4558	S000004883	ORF	Verified	YMR270C	RRN9	13	806422	805325	C	Upstream activation factor subunit
4560	S000004884	ORF	Verified	YMR271C	URA10	13	807547	806864	C	One of two orotate phosphoribosyltransferase isozymes (see also URA5) that catalyze the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate
4562	S000006690	tRNA	n.a.	tQ(CUG)M	CDC65	13	808316	808245	C	Glutamine tRNA with anticodon CUG
4566	S000028695	ORF	Dubious	YMR272W-A	n.a.	13	810465	810578	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4568	S000004885	ORF	Verified	YMR272C	SCS7	13	810776	809622	C	Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth
4570	S000028696	ORF	Uncharacterized	YMR272W-B	n.a.	13	811088	811195	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4572	S000004886	ORF	Verified	YMR273C	ZDS1	13	813979	811232	C	Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; has a role in localization of Bcy1p, a regulatory subunit of protein kinase A; implicated in mRNA nuclear export
4574	S000004887	ORF	Verified	YMR274C	RCE1	13	815310	814363	C	Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mating pheromone
4576	S000004888	ORF	Verified	YMR275C	BUL1	13	818580	815650	C	Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases
4578	S000004889	ORF	Verified	YMR276W	DSK2	13	818826	819947	W	Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle, involved in proteolysis, interacts with the proteasome
4580	S000004890	ORF	Verified	YMR277W	FCP1	13	820255	822453	W	Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p)
4582	S000004891	ORF	Uncharacterized	YMR278W	n.a.	13	822762	824630	W	Hypothetical protein
4584	S000004892	ORF	Uncharacterized	YMR279C	n.a.	13	826350	824728	C	Hypothetical protein
4586	S000004893	ORF	Verified	YMR280C	CAT8	13	831328	827027	C	Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements
4588	S000004894	ORF	Verified	YMR281W	GPI12	13	832338	833252	W	ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly, the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp
4590	S000004895	ORF	Verified	YMR282C	AEP2	13	835097	833355	C	Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader
4592	S000004896	ORF	Verified	YMR283C	RIT1	13	836866	835325	C	2'-O-ribosyl phosphate transferase, modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA
4595	S000006784	tRNA	n.a.	tY(GUA)M2	SUP8	13	837927	838015	W	tRNA-Tyr
4596	S000032300	intron	n.a.	n.a.	n.a.	13	837966	837979	W	n.a.
4599	S000004897	ORF	Verified	YMR284W	YKU70	13	838186	839994	W	Forms heterodimer with Yku80p known as Ku, binds chromosome ends and is involved in maintaining normal telomere length and structure, in addition to participating in the formation of silent chromatin at telomere-proximal genes
4601	S000004898	ORF	Verified	YMR285C	NGL2	13	841690	840143	C	Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p
4603	S000004899	ORF	Verified	YMR286W	MRPL33	13	841941	842201	W	Mitochondrial ribosomal protein of the large subunit
4605	S000004900	ORF	Verified	YMR287C	MSU1	13	845344	842435	C	RNase, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs
4607	S000004901	ORF	Verified	YMR288W	HSH155	13	845570	848485	W	U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155
4609	S000004902	ORF	Uncharacterized	YMR289W	n.a.	13	848684	849808	W	4-amino-4-deoxychorismate lyase, catalyzes the third step in para-aminobenzoic acid biosynthesis
4611	S000004904	ORF	Dubious	YMR290W-A	n.a.	13	851421	851768	W	Protein required for cell viability
4613	S000004903	ORF	Verified	YMR290C	HAS1	13	851590	850073	C	ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles
4615	S000004905	ORF	Uncharacterized	YMR291W	n.a.	13	852629	854389	W	Hypothetical protein
4617	S000004906	ORF	Verified	YMR292W	GOT1	13	854794	855292	W	Evolutionarily conserved non-essential protein present in early Golgi cisternae that may be involved in ER-Golgi transport at a step after vesicle tethering to Golgi membranes, exhibits membrane topology similar to that of Sft2p
4620	S000037004	intron	n.a.	n.a.	n.a.	13	854816	854897	W	n.a.
4621	S000004907	ORF	Uncharacterized	YMR293C	n.a.	13	856792	855398	C	protein similar to bacterial glutamyl-tRNA amidotransferases
4623	S000004908	ORF	Verified	YMR294W	JNM1	13	856965	858086	W	Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B
4625	S000004909	ORF	Dubious	YMR294W-A	n.a.	13	858208	858567	W	Hypothetical protein
4627	S000004910	ORF	Uncharacterized	YMR295C	n.a.	13	858889	858296	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud
4629	S000004911	ORF	Verified	YMR296C	LCB1	13	860890	859214	C	Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
4631	S000004912	ORF	Verified	YMR297W	PRC1	13	861921	863519	W	Vacuolar carboxypeptidase Y (proteinase C), involved in protein degradation in the vacuole and required for full protein degradation during sporulation
4633	S000004913	ORF	Verified	YMR298W	LIP1	13	863818	864270	W	Ceramide synthase subunit; single-span ER membrane protein associated with Lag1p and Lac1p and required for ceramide synthase activity, null mutant grows extremely slowly and is defective in ceramide synthesis
4635	S000004914	ORF	Verified	YMR299C	DYN3	13	865349	864411	C	Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration
4637	S000004915	ORF	Verified	YMR300C	ADE4	13	867090	865558	C	Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway
4639	S000004916	ORF	Verified	YMR301C	ATM1	13	869626	867554	C	Mitochondrial inner membrane transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol; member of the ATP-binding cassette (ABC) transporter family
4641	S000004917	ORF	Verified	YMR302C	PRP12	13	872624	870072	C	Integral inner mitochondrial membrane protein with similarity to exonucleases; prp12 mutants exhibit an increased rate of mt DNA escape
4643	S000004918	ORF	Verified	YMR303C	ADH2	13	874336	873290	C	Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1
4645	S000004920	ORF	Verified	YMR304W	UBP15	13	874986	878678	W	Ubiquitin-specific protease that may play a role in ubiquitin precursor processing
4647	S000004919	ORF	Dubious	YMR304C-A	n.a.	13	879129	878779	C	Hypothetical protein
4649	S000004921	ORF	Verified	YMR305C	SCW10	13	880231	879062	C	Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p
4651	S000004923	ORF	Verified	YMR306W	FKS3	13	881158	886515	W	Protein of unknown function, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p
4653	S000004922	ORF	Dubious	YMR306C-A	n.a.	13	886571	886182	C	Hypothetical protein
4655	S000004924	ORF	Verified	YMR307W	GAS1	13	887002	888681	W	Beta-1.3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor
4657	S000028578	ORF	Dubious	YMR307C-A	n.a.	13	887924	887730	C	Identified by fungal homology and RT-PCR
4659	S000004925	ORF	Verified	YMR308C	PSE1	13	892220	888951	C	Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p
4661	S000004926	ORF	Verified	YMR309C	NIP1	13	895425	892987	C	Subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection
4663	S000004927	ORF	Uncharacterized	YMR310C	n.a.	13	896668	895715	C	Hypothetical protein
4665	S000004928	ORF	Verified	YMR311C	GLC8	13	897602	896913	C	Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2
4667	S000004929	ORF	Verified	YMR312W	ELP6	13	898404	899225	W	Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subunit component of the RNA polymerase II holoenzyme; required for Elongator structural integrity and histone acetyltransferase activity
4669	S000004930	ORF	Verified	YMR313C	TGL3	13	901306	899378	C	Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes
4671	S000004931	ORF	Verified	YMR314W	PRE5	13	901708	902412	W	20S proteasome alpha-type subunit
4673	S000004932	ORF	Uncharacterized	YMR315W	n.a.	13	902799	903848	W	Hypothetical protein
4675	S000028697	ORF	Uncharacterized	YMR315W-A	n.a.	13	904285	904392	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4677	S000004935	ORF	Verified	YMR316W	DIA1	13	904823	905833	W	Protein of unknown function, involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
4679	S000004933	ORF	Dubious	YMR316C-A	n.a.	13	905971	905660	C	Hypothetical protein
4681	S000004936	ORF	Uncharacterized	YMR317W	n.a.	13	907362	910784	W	Hypothetical protein
4683	S000004934	ORF	Dubious	YMR316C-B	n.a.	13	907627	907319	C	Hypothetical protein
4685	S000004937	ORF	Verified	YMR318C	ADH6	13	912141	911059	C	NADPH-dependent cinnamyl alcohol dehydrogenase family member with broad substrate specificity; may be involved in fusel alcohol synthesis or in aldehyde tolerance
4687	S000004938	ORF	Verified	YMR319C	FET4	13	914536	912878	C	Low-affinity Fe(II) transporter of the plasma membrane
4689	S000004939	ORF	Dubious	YMR320W	n.a.	13	916744	917049	W	Hypothetical protein
4691	S000004940	ORF	Uncharacterized	YMR321C	n.a.	13	917894	917577	C	Hypothetical protein
4693	S000004941	ORF	Uncharacterized	YMR322C	SNO4	13	919077	918364	C	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Hsp33p; member of the DJ-1/ThiJ/PfpI superfamily; may have a role in pyridoxine metabolism
4695	S000004942	ORF	Verified	YMR323W	ERR3	13	920086	921399	W	Protein of unknown function, has similarity to enolases
4697	S000004943	ORF	Dubious	YMR324C	n.a.	13	922442	922200	C	Hypothetical protein
4699	S000004944	ORF	Uncharacterized	YMR325W	n.a.	13	922639	923013	W	Hypothetical protein
4705	S000004945	ORF	Dubious	YMR326C	n.a.	13	923800	923492	C	Hypothetical protein
4710	S000028704	ORF	Dubious	YNL339W-B	n.a.	14	734	1216	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4712	S000028703	ORF	Dubious	YNL339W-A	n.a.	14	1517	2092	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
4714	S000005283	ORF	Verified	YNL339C	YRF1-6	14	6098	371	C	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
4717	S000031359	intron	n.a.	n.a.	n.a.	14	6079	5932	C	n.a.
4718	S000005282	ORF	Dubious	YNL338W	n.a.	14	6561	6719	W	Hypothetical protein
4725	S000005281	ORF	Dubious	YNL337W	n.a.	14	7165	7419	W	Hypothetical protein
4730	S000005280	ORF	Verified	YNL336W	COS1	14	8330	9475	W	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
4732	S000005279	ORF	Uncharacterized	YNL335W	n.a.	14	11452	12129	W	Hypothetical protein
4734	S000005278	ORF	Verified	YNL334C	SNO2	14	12876	12208	C	Protein of unknown function, nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin
4736	S000005277	ORF	Verified	YNL333W	SNZ2	14	13267	14163	W	Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p
4738	S000005276	ORF	Verified	YNL332W	THI12	14	14832	15854	W	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
4740	S000005275	ORF	Verified	YNL331C	AAD14	14	17248	16118	C	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
4742	S000005274	ORF	Verified	YNL330C	RPD3	14	19302	18001	C	Histone deacetylase; regulates transcription and silencing
4744	S000005273	ORF	Verified	YNL329C	PEX6	14	22633	19541	C	Peroxisomal membrane AAA-family ATPase peroxin required for peroxisome assembly, contains two 230 amino acid ATP-binding AAA cassettes, interacts with Pex1p
4746	S000005272	ORF	Verified	YNL328C	MDJ2	14	23274	22834	C	Protein of the mitochondrial inner membrane; function partially overlaps that of Mdj1p, which is a chaperone involved in folding of mitochondrially synthesized proteins in the mitochondrial matrix; member of the DnaJ family
4748	S000005271	ORF	Verified	YNL327W	EGT2	14	24047	27172	W	Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner
4750	S000005270	ORF	Uncharacterized	YNL326C	n.a.	14	28346	27336	C	Palmitoyltransferase for Vac8p, one of three yeast DHHC-cysteine rich domain proteins (Pfa3p, Erf2p, Akr1p) with palmitoyltransferase activity; required for vacuolar integrity under stress conditions
4752	S000005268	ORF	Dubious	YNL324W	n.a.	14	31049	31444	W	Hypothetical protein
4754	S000005269	ORF	Verified	YNL325C	FIG4	14	31377	28738	C	Protein required for efficient mating, member of a family of eukaryotic proteins that contain a domain homologous to Sac1p
4756	S000005267	ORF	Verified	YNL323W	LEM3	14	31943	33187	W	Membrane protein of the plasma membrane and ER, involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane
4758	S000005266	ORF	Verified	YNL322C	KRE1	14	34234	33293	C	Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor
4760	S000005265	ORF	Uncharacterized	YNL321W	n.a.	14	34695	37421	W	Protein of unknown function, potential Cdc28p substrate
4762	S000005264	ORF	Uncharacterized	YNL320W	n.a.	14	37699	38553	W	Hypothetical protein
4764	S000005263	ORF	Dubious	YNL319W	n.a.	14	38641	39081	W	Hypothetical protein
4766	S000005262	ORF	Verified	YNL318C	HXT14	14	40328	38706	C	Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
4768	S000005261	ORF	Verified	YNL317W	PFS2	14	40618	42015	W	Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex
4770	S000005260	ORF	Verified	YNL316C	PHA2	14	43074	42070	C	Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway
4772	S000005259	ORF	Verified	YNL315C	ATP11	14	44279	43323	C	Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase
4774	S000005258	ORF	Verified	YNL314W	DAL82	14	44446	45213	W	Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain
4776	S000005257	ORF	Uncharacterized	YNL313C	n.a.	14	48021	45307	C	Protein required for cell viability
4778	S000005256	ORF	Verified	YNL312W	RFA2	14	48286	49215	W	Subunit of heterotrimeric Replication Factor A (RF-A), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination
4781	S000036980	intron	n.a.	n.a.	n.a.	14	48293	48400	W	n.a.
4782	S000005255	ORF	Uncharacterized	YNL311C	n.a.	14	51687	49396	C	F-box protein
4784	S000005254	ORF	Verified	YNL310C	ZIM17	14	52523	51906	C	Essential component of the mitochondrial import system; zinc finger protein that may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix
4786	S000005253	ORF	Verified	YNL309W	STB1	14	52661	53923	W	Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated
4788	S000005252	ORF	Verified	YNL308C	KRI1	14	55896	54121	C	Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p
4790	S000005251	ORF	Verified	YNL307C	MCK1	14	57573	56446	C	Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family
4792	S000005250	ORF	Verified	YNL306W	MRPS18	14	58155	58808	W	Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins
4794	S000005249	ORF	Uncharacterized	YNL305C	n.a.	14	59791	58898	C	Hypothetical protein
4796	S000005248	ORF	Verified	YNL304W	YPT11	14	60482	61549	W	Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p to mediate distribution of mitochondria to daughter cells
4798	S000005247	ORF	Dubious	YNL303W	n.a.	14	61509	61856	W	Hypothetical protein
4800	S000005246	ORF	Verified	YNL302C	RPS19B	14	62942	61957	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps19Ap and has similarity to rat S19 ribosomal protein
4803	S000032916	intron	n.a.	n.a.	n.a.	14	62922	62372	C	n.a.
4804	S000005245	ORF	Verified	YNL301C	RPL18B	14	64561	63569	C	Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein
4807	S000032847	intron	n.a.	n.a.	n.a.	14	64449	64018	C	n.a.
4808	S000005244	ORF	Uncharacterized	YNL300W	n.a.	14	65743	66051	W	Hypothetical protein
4810	S000005243	ORF	Verified	YNL299W	TRF5	14	66516	68393	W	Putative poly (A) polymerase involved in nuclear RNA quality control based on: homology with Trf4p, genetic interactions with TRF4 mutants, and physical interaction with Mtr4p (subunit of TRAMP); disputed role as a sigma DNA polymerase
4812	S000005242	ORF	Verified	YNL298W	CLA4	14	68913	71441	W	Involved in localizing cell growth with respect to the septin ring; protein kinase, homologous to Ste20p, interacts with CDC42
4814	S000005240	ORF	Dubious	YNL296W	n.a.	14	76271	76585	W	Hypothetical protein
4816	S000005241	ORF	Verified	YNL297C	MON2	14	76581	71671	C	Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins
4818	S000005239	ORF	Uncharacterized	YNL295W	n.a.	14	76944	78518	W	Hypothetical protein
4820	S000005238	ORF	Verified	YNL294C	RIM21	14	80258	78657	C	Protein proposed to be involved in the response to alkaline pH; has similarity to A. nidulans PalH
4822	S000005237	ORF	Verified	YNL293W	MSB3	14	80638	82539	W	GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth
4824	S000005236	ORF	Verified	YNL292W	PUS4	14	82804	84015	W	Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)
4826	S000005235	ORF	Verified	YNL291C	MID1	14	85813	84167	C	N-glycosylated integral membrane protein of the ER membrane and plasma membrane, required for Ca2+ influx stimulated by pheromone, functions as a stretch-activated Ca2+-permeable cation channel in mammals; forms an oligomer
4828	S000005234	ORF	Verified	YNL290W	RFC3	14	86216	87238	W	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
4830	S000005233	ORF	Verified	YNL289W	PCL1	14	87895	88734	W	Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth
4832	S000007304	snoRNA	n.a.	snR40	SNR40	14	89208	89304	W	Small nucleolar RNA; small nucleolar RNA
4834	S000005232	ORF	Verified	YNL288W	CAF40	14	90301	91422	W	Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p
4836	S000005231	ORF	Verified	YNL287W	SEC21	14	91992	94799	W	Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in  ER to Golgi transport of selective cargo
4838	S000005230	ORF	Verified	YNL286W	CUS2	14	95221	96078	W	Protein that binds to U2 snRNA and Prp11p, may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs)
4840	S000005229	ORF	Dubious	YNL285W	n.a.	14	96171	96542	W	Hypothetical protein
4842	S000006591	tRNA	n.a.	tG(UCC)N	SUF6	14	96310	96239	C	tRNA-Gly
4855	S000006673	tRNA	n.a.	tN(GUU)N1	n.a.	14	102714	102787	W	tRNA-Asn
4857	S000005228	ORF	Verified	YNL284C	MRPL10	14	104100	103132	C	Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels
4859	S000006744	tRNA	n.a.	tT(AGU)N1	n.a.	14	104803	104875	W	tRNA-Thr
4861	S000005227	ORF	Verified	YNL283C	WSC2	14	106693	105182	C	cell wall integrity and stress response component 2; Putative integral membrane protein containing novel cysteine motif. Similarity to SLG1 (WSC1), WSC3 and WSC4
4863	S000005226	ORF	Verified	YNL282W	POP3	14	107685	108272	W	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
4865	S000005225	ORF	Verified	YNL281W	HCH1	14	108465	108926	W	Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus
4867	S000005224	ORF	Verified	YNL280C	ERG24	14	110409	109093	C	C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions
4869	S000005223	ORF	Verified	YNL279W	PRM1	14	110915	112900	W	Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p
4871	S000005222	ORF	Verified	YNL278W	CAF120	14	113269	116451	W	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation
4873	S000028852	ORF	Uncharacterized	YNL277W-A	n.a.	14	116677	116865	W	Identified by expression profiling and mass spectrometry
4875	S000005221	ORF	Verified	YNL277W	MET2	14	117347	118807	W	L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway
4877	S000005220	ORF	Dubious	YNL276C	n.a.	14	118824	118429	C	Hypothetical protein
4879	S000005219	ORF	Verified	YNL275W	n.a.	14	119266	120996	W	Plasma membrane protein that binds HCO3-, I-, Br-, NO3- and Cl- ; putative boron efflux transporter with similarity to A. thaliana BOR1 which is a known boron efflux transporter
4881	S000005218	ORF	Uncharacterized	YNL274C	n.a.	14	122168	121116	C	Putative hydroxyisocaproate dehydrogenase
4883	S000005217	ORF	Verified	YNL273W	TOF1	14	122881	126597	W	Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase
4885	S000005216	ORF	Verified	YNL272C	SEC2	14	129082	126803	C	Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cytoplasmic vesicles; essential for post-Golgi vesicle transport
4887	S000005215	ORF	Verified	YNL271C	BNI1	14	135382	129521	C	Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1
4889	S000005214	ORF	Verified	YNL270C	ALP1	14	137660	135939	C	Basic amino acid transporter, involved in uptake of cationic amino acids
4891	S000005213	ORF	Verified	YNL269W	BSC4	14	137698	138093	W	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p
4893	S000005212	ORF	Verified	YNL268W	LYP1	14	138549	140384	W	Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids
4895	S000005211	ORF	Verified	YNL267W	PIK1	14	140877	144077	W	Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokineses through the actin cytoskeleton
4897	S000005210	ORF	Dubious	YNL266W	n.a.	14	144244	144663	W	Hypothetical protein
4899	S000005209	ORF	Verified	YNL265C	IST1	14	145280	144279	C	Putative translation initiation factor, as suggested by computational analysis of large-scale protein-protein interaction data
4902	S000030433	intron	n.a.	n.a.	n.a.	14	145253	145149	C	n.a.
4903	S000005208	ORF	Verified	YNL264C	PDR17	14	146614	145562	C	Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition
4905	S000005207	ORF	Verified	YNL263C	YIF1	14	147839	146895	C	Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles
4907	S000005206	ORF	Verified	YNL262W	POL2	14	148211	154879	W	Catalytic subunit of DNA polymerase epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair
4909	S000005205	ORF	Verified	YNL261W	ORC5	14	155099	156538	W	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
4911	S000005204	ORF	Uncharacterized	YNL260C	n.a.	14	157454	156858	C	Protein required for cell viability
4913	S000005203	ORF	Verified	YNL259C	ATX1	14	157864	157643	C	Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake
4915	S000005202	ORF	Verified	YNL258C	DSL1	14	160372	158108	C	Endoplasmic reticulum (ER)-localized peripheral membrane protein required for Golgi-to-ER retrograde traffic; component of the ER target site that interacts with coatomer, the major component of the COPI vesicle protein coat
4917	S000005201	ORF	Verified	YNL257C	SIP3	14	164319	160630	C	Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate
4919	S000005200	ORF	Verified	YNL256W	FOL1	14	164622	167096	W	Multifunctional enzyme of the folic acid biosynthesis pathway, has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities
4921	S000005199	ORF	Verified	YNL255C	GIS2	14	167789	167328	C	Putative zinc finger protein with similarity to human CNBP, proposed to be involved in the RAS/cAMP signaling pathway
4923	S000005198	ORF	Uncharacterized	YNL254C	n.a.	14	169247	168042	C	Hypothetical protein
4926	S000005197	ORF	Verified	YNL253W	TEX1	14	170017	171285	W	transcription export complex component
4928	S000005196	ORF	Verified	YNL252C	MRPL17	14	172285	171440	C	Mitochondrial ribosomal protein of the large subunit
4930	S000005195	ORF	Verified	YNL251C	NRD1	14	174314	172587	C	RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs
4932	S000005194	ORF	Verified	YNL250W	RAD50	14	175409	179347	W	Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining
4934	S000005193	ORF	Verified	YNL249C	MPA43	14	181021	179393	C	Mitochondrial protein of unknown function
4936	S000005192	ORF	Verified	YNL248C	RPA49	14	182607	181360	C	RNA polymerase I subunit A49
4938	S000005191	ORF	Uncharacterized	YNL247W	n.a.	14	182874	185177	W	Protein required for cell viability
4940	S000005190	ORF	Verified	YNL246W	VPS75	14	185459	186348	W	Protein of unknown function involved in vacuolar protein sorting; detected in the nucleus
4943	S000031151	intron	n.a.	n.a.	n.a.	14	185491	185585	W	n.a.
4944	S000005189	ORF	Verified	YNL245C	CWC25	14	186884	186345	C	Component of a complex containing Cef1p, involved in pre-mRNA splicing; has similarity to S. pombe Cwf25p
4946	S000005188	ORF	Verified	YNL244C	SUI1	14	187495	187169	C	Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation and elongation phases
4948	S000005187	ORF	Verified	YNL243W	SLA2	14	188050	190956	W	Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo
4950	S000005186	ORF	Verified	YNL242W	ATG2	14	191323	196101	W	Peripheral membrane protein required for the formation of cytosolic sequestering vesicles involved in vacuolar import through both the Cvt pathway and autophagy; interacts with Atg9p and is necessary for its trafficking
4953	S000005185	ORF	Verified	YNL241C	ZWF1	14	197942	196425	C	Glucose-6-phosphate dehydrogenase
4955	S000005184	ORF	Verified	YNL240C	NAR1	14	199976	198501	C	Nuclear architecture related protein; component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of cytosolic and nuclear FeS proteins; homologous to human Narf
4957	S000005183	ORF	Verified	YNL239W	LAP3	14	200568	201932	W	Aminopeptidase of cysteine protease family, has a DNA binding activity and acts as bleomycin hydrolase in vitro; transcription is regulated by galactose via Gal4p
4959	S000005182	ORF	Verified	YNL238W	KEX2	14	202427	204871	W	Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway
4961	S000005181	ORF	Verified	YNL237W	YTP1	14	205187	206566	W	Probable type-III integral membrane protein of unknown function, has regions of similarity to mitochondrial electron transport proteins
4963	S000005180	ORF	Verified	YNL236W	SIN4	14	206929	209853	W	Subunit of the Mediator complex; interacts with the RNA polymerase II holoenzyme to postively or negatively regulate transcription; dispensible for basal transcription
4965	S000005179	ORF	Dubious	YNL235C	n.a.	14	209978	209547	C	Hypothetical protein
4967	S000005178	ORF	Uncharacterized	YNL234W	n.a.	14	210232	211512	W	Similar to globins and has a functional heme-binding domain; involved in glucose signaling or metabolism; regulated by Rgt1p
4969	S000005177	ORF	Verified	YNL233W	BNI4	14	211921	214599	W	Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p
4971	S000005176	ORF	Verified	YNL232W	CSL4	14	214922	215800	W	Subunit of the exosome, which is an essential complex present in both nucleus and cytoplasm that mediates RNA processing and degradation
4973	S000005175	ORF	Verified	YNL231C	PDR16	14	217041	215986	C	Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p
4975	S000005174	ORF	Verified	YNL230C	ELA1	14	218661	217522	C	Elongin A, F-box protein that forms a heterodimer with Elc1p and participates in transcription elongation
4977	S000005173	ORF	Verified	YNL229C	URE2	14	220200	219136	C	Nitrogen catabolite repression regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion
4979	S000005172	ORF	Dubious	YNL228W	n.a.	14	220644	221420	W	Hypothetical protein
4981	S000005170	ORF	Dubious	YNL226W	n.a.	14	222238	222648	W	Hypothetical protein
4983	S000005171	ORF	Uncharacterized	YNL227C	JJJ1	14	222430	220658	C	Protein that contains a 70 amino acid J-domain, may function as a co-chaperone to recruit Hsp70-like activity to specific sites; mutation causes defects in fluid-phase endocytosis
4985	S000005169	ORF	Verified	YNL225C	CNM67	14	224468	222723	C	Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclear migration
4987	S000005168	ORF	Uncharacterized	YNL224C	n.a.	14	227098	224795	C	Hypothetical protein
4989	S000005167	ORF	Verified	YNL223W	ATG4	14	227369	228853	W	Cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation; mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p
4991	S000005166	ORF	Verified	YNL222W	SSU72	14	229093	229713	W	Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p, exhibits intrinsic phosphatase activity, affects start site selection in vivo; Nuclear zinc-finger motif containing protein.
4993	S000007295	snRNA	n.a.	snR19	SNR19	14	230671	230104	C	U1 spliceosomal RNA; snRNA U1 homolog
4995	S000005165	ORF	Verified	YNL221C	POP1	14	233694	231067	C	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P
4997	S000005164	ORF	Verified	YNL220W	ADE12	14	234412	235713	W	Adenylosuccinate synthase, catalyzes the first committed step in the 'de novo' biosynthesis of adenosine
4999	S000005163	ORF	Verified	YNL219C	ALG9	14	237662	235995	C	Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation
5001	S000005162	ORF	Verified	YNL218W	MGS1	14	238237	240000	W	Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP)
5003	S000005161	ORF	Uncharacterized	YNL217W	n.a.	14	240330	241310	W	Hypothetical protein
5005	S000005160	ORF	Verified	YNL216W	RAP1	14	241688	244171	W	DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure
5007	S000005159	ORF	Verified	YNL215W	IES2	14	244467	245429	W	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
5009	S000005158	ORF	Verified	YNL214W	PEX17	14	245616	246215	W	Peroxisomal membrane protein component of the peroxisomal translocation machinery, required for peroxisome biogenesis, binds Pex14p
5011	S000005157	ORF	Uncharacterized	YNL213C	n.a.	14	247103	246459	C	Hypothetical protein
5013	S000005156	ORF	Verified	YNL212W	VID27	14	247460	249808	W	Cytoplasmic protein possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth
5015	S000005155	ORF	Uncharacterized	YNL211C	n.a.	14	250314	250054	C	Hypothetical protein
5018	S000005154	ORF	Verified	YNL210W	MER1	14	250930	251742	W	Protein with RNA-binding motifs required for meiosis-specific mRNA splicing; required for chromosome pairing and meiotic recombination
5020	S000005153	ORF	Verified	YNL209W	SSB2	14	252058	253899	W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone; may be involved in the folding of newly-synthesized polypeptide chains; member of the heat shock protein 70 (HSP70) family; homolog of SSB1
5022	S000005152	ORF	Uncharacterized	YNL208W	n.a.	14	254417	255016	W	Hypothetical protein
5024	S000005151	ORF	Verified	YNL207W	RIO2	14	255352	256629	W	Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p
5026	S000005150	ORF	Verified	YNL206C	RTT106	14	258154	256787	C	Protein with a role in regulation of Ty1 transposition
5028	S000005149	ORF	Dubious	YNL205C	n.a.	14	258576	258154	C	Hypothetical protein
5030	S000005148	ORF	Verified	YNL204C	SPS18	14	259276	258374	C	Protein of unknown function, contains a putative zinc-binding domain; expressed during sporulation
5032	S000005146	ORF	Verified	YNL202W	SPS19	14	259568	260455	W	Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate
5034	S000005147	ORF	Dubious	YNL203C	n.a.	14	260049	259438	C	Hypothetical protein
5036	S000005145	ORF	Uncharacterized	YNL201C	PSY2	14	263202	260626	C	Nuclear protein of unknown function; deletion results in sensitivity to anticancer drugs oxaliplatin and cisplatin, but not mitomycin C; deletion is synthetically lethal with a chitin synthase (CHS1) null mutant
5038	S000005144	ORF	Uncharacterized	YNL200C	n.a.	14	264452	263712	C	Hypothetical protein; similarity to human TGR-CL10C, thyroidal receptor for N-acetylglucosamine
5040	S000005143	ORF	Verified	YNL199C	GCR2	14	266529	264925	C	Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p
5042	S000005142	ORF	Dubious	YNL198C	n.a.	14	266815	266513	C	Hypothetical protein
5044	S000005141	ORF	Verified	YNL197C	WHI3	14	269592	267607	C	RNA binding protein that binds to and sequesters the G1 cyclin CLN3 mRNA; regulates cell fate and dose-dependently inhibits passage through Start by regulating the critical cell size requirement necessary for cell cycle progression
5046	S000005140	ORF	Uncharacterized	YNL196C	n.a.	14	271170	270274	C	Sporulation-specific protein with a leucine zipper motif
5048	S000005139	ORF	Uncharacterized	YNL195C	n.a.	14	272307	271522	C	Hypothetical protein
5050	S000005138	ORF	Uncharacterized	YNL194C	n.a.	14	273614	272709	C	Hypothetical protein
5052	S000005137	ORF	Uncharacterized	YNL193W	n.a.	14	274367	276043	W	Hypothetical protein
5054	S000005136	ORF	Verified	YNL192W	CHS1	14	276501	279896	W	Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor
5057	S000005135	ORF	Uncharacterized	YNL191W	n.a.	14	280431	281504	W	Hypothetical protein
5059	S000005134	ORF	Uncharacterized	YNL190W	n.a.	14	282394	283008	W	Hypothetical protein
5061	S000005133	ORF	Verified	YNL189W	SRP1	14	284259	285887	W	Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation
5063	S000005132	ORF	Verified	YNL188W	KAR1	14	286307	287608	W	Essential protein involved in karyogamy during mating and in spindle pole body duplication during mitosis, localizes to the half-bridge of the spindle pole body, interacts with Spc72p during karyogamy, also interacts with Cdc31p
5065	S000005131	ORF	Uncharacterized	YNL187W	n.a.	14	287994	289067	W	Non-essential protein with putative leucine-rich nuclear export signal (NES) sequence that fits the consensus sequence recognized by Crm1p
5067	S000005130	ORF	Verified	YNL186W	UBP10	14	289498	291876	W	Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus
5069	S000005129	ORF	Verified	YNL185C	MRPL19	14	292669	292193	C	Mitochondrial ribosomal protein of the large subunit
5071	S000005128	ORF	Dubious	YNL184C	n.a.	14	292883	292557	C	Hypothetical protein
5073	S000005127	ORF	Verified	YNL183C	NPR1	14	295509	293137	C	Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation
5075	S000005126	ORF	Uncharacterized	YNL182C	IPI3	14	297627	295960	C	Protein required for cell viability; computational analysis of large-scale protein-protein interaction data suggests a possible role in assembly of the ribosomal large subunit
5077	S000005125	ORF	Uncharacterized	YNL181W	n.a.	14	298335	299558	W	Protein required for cell viability
5079	S000005124	ORF	Verified	YNL180C	RHO5	14	300649	299654	C	Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity
5081	S000005123	ORF	Dubious	YNL179C	n.a.	14	301103	300666	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; deletion in cyr1 mutant results in loss of stress resistance
5083	S000005122	ORF	Verified	YNL178W	RPS3	14	302680	303402	W	Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
5085	S000005121	ORF	Verified	YNL177C	MRPL22	14	304615	303686	C	Mitochondrial ribosomal protein of the large subunit
5087	S000005120	ORF	Uncharacterized	YNL176C	n.a.	14	306980	305070	C	Hypothetical protein
5089	S000005118	ORF	Dubious	YNL174W	n.a.	14	308074	308646	W	Hypothetical protein
5091	S000005119	ORF	Verified	YNL175C	NOP13	14	308612	307401	C	Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA
5093	S000005117	ORF	Verified	YNL173C	MDG1	14	310057	308957	C	Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations
5095	S000005116	ORF	Verified	YNL172W	APC1	14	310636	315882	W	Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
5097	S000005114	ORF	Dubious	YNL170W	n.a.	14	315978	316373	W	Sporulation
5099	S000005115	ORF	Dubious	YNL171C	n.a.	14	315997	315629	C	Hypothetical protein
5101	S000005113	ORF	Verified	YNL169C	PSD1	14	317671	316169	C	Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts phosphatidylserine to phosphatidylethanolamine
5103	S000005112	ORF	Uncharacterized	YNL168C	n.a.	14	318809	318030	C	The authentic, non-tagged protein was localized to mitochondria
5105	S000005111	ORF	Verified	YNL167C	SKO1	14	321359	319416	C	Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family that forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in the osmotic and oxidative stress responses
5107	S000005110	ORF	Verified	YNL166C	BNI5	14	323565	322219	C	Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner
5109	S000005109	ORF	Uncharacterized	YNL165W	n.a.	14	323832	325052	W	Hypothetical protein
5111	S000005108	ORF	Verified	YNL164C	IBD2	14	326320	325265	C	Component of the BUB2-dependent spindle checkpoint pathway, interacts with Bfa1p and functions upstream of Bub2p and Bfa1p
5113	S000005107	ORF	Verified	YNL163C	RIA1	14	330073	326741	C	Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p)
5115	S000007624	ORF	Uncharacterized	YNL162W-A	n.a.	14	330329	330547	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
5117	S000005106	ORF	Verified	YNL162W	RPL42A	14	331322	332154	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein
5120	S000034974	intron	n.a.	n.a.	n.a.	14	331326	331837	W	n.a.
5121	S000005105	ORF	Verified	YNL161W	CBK1	14	332597	334867	W	Protein kinase involved in cell wall biosynthesis; required for efficient apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation
5123	S000005104	ORF	Verified	YNL160W	YGP1	14	336545	337609	W	Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p
5125	S000005103	ORF	Verified	YNL159C	ASI2	14	339347	338478	C	Predicted membrane protein; genetic interactions suggest a role in negative regulation of amino acid uptake
5127	S000005102	ORF	Uncharacterized	YNL158W	n.a.	14	339612	340208	W	Essential protein required for maturation of Gas1p and Pho8p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
5129	S000005101	ORF	Uncharacterized	YNL157W	n.a.	14	340352	340858	W	Hypothetical protein
5131	S000005100	ORF	Uncharacterized	YNL156C	n.a.	14	341968	341069	C	Protein of unknown function, potential homolog of mammalian Insig 1
5133	S000005099	ORF	Uncharacterized	YNL155W	n.a.	14	342516	343340	W	Hypothetical protein
5135	S000005098	ORF	Verified	YNL154C	YCK2	14	345276	343636	C	Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p
5137	S000005097	ORF	Verified	YNL153C	GIM3	14	346058	345669	C	Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
5139	S000005096	ORF	Uncharacterized	YNL152W	n.a.	14	346313	347542	W	Protein required for cell viability
5141	S000005095	ORF	Verified	YNL151C	RPC31	14	348521	347766	C	RNA polymerase III subunit C31; contains HMG-like C-terminal domain
5143	S000005094	ORF	Dubious	YNL150W	n.a.	14	349251	349658	W	Protein required for cell viability
5145	S000005093	ORF	Uncharacterized	YNL149C	n.a.	14	349756	349367	C	Protein required for cell viability
5147	S000005092	ORF	Verified	YNL148C	ALF1	14	350671	349907	C	Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance
5149	S000005091	ORF	Verified	YNL147W	LSM7	14	350940	351383	W	Component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
5152	S000031003	intron	n.a.	n.a.	n.a.	14	350958	351077	W	n.a.
5153	S000028851	ORF	Uncharacterized	YNL146C-A	n.a.	14	351580	351386	C	Identified by expression profiling and mass spectrometry
5155	S000005090	ORF	Uncharacterized	YNL146W	n.a.	14	351715	352017	W	Hypothetical protein
5157	S000005089	ORF	Verified	YNL145W	MFA2	14	352414	352530	W	Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1
5159	S000028702	ORF	Dubious	YNL144W-A	n.a.	14	353061	353144	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5161	S000005088	ORF	Uncharacterized	YNL144C	n.a.	14	355042	352820	C	Hypothetical protein
5163	S000005087	ORF	Dubious	YNL143C	n.a.	14	357186	356794	C	Hypothetical protein
5165	S000005086	ORF	Verified	YNL142W	MEP2	14	357453	358952	W	Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation
5167	S000005085	ORF	Verified	YNL141W	AAH1	14	359596	360639	W	Adenine deaminase (adenine aminohydrolase), involved in purine salvage and nitrogen catabolism
5169	S000005084	ORF	Dubious	YNL140C	n.a.	14	361486	360917	C	Hypothetical protein
5171	S000005083	ORF	Verified	YNL139C	RLR1	14	365717	360924	C	Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids
5173	S000028509	ORF	Uncharacterized	YNL138W-A	n.a.	14	366033	366412	W	Component of the U2 snRNP, associated with the SF3b complex; conserved in Ashbya gossypii
5176	S000030225	intron	n.a.	n.a.	n.a.	14	366036	366157	W	n.a.
5177	S000005082	ORF	Verified	YNL138W	SRV2	14	366741	368321	W	CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis
5179	S000005081	ORF	Verified	YNL137C	NAM9	14	370055	368595	C	Mitochondrial ribosomal component of the small subunit
5181	S000005080	ORF	Verified	YNL136W	EAF7	14	370368	371645	W	Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A
5183	S000005079	ORF	Verified	YNL135C	FPR1	14	372226	371882	C	Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function
5185	S000005078	ORF	Uncharacterized	YNL134C	n.a.	14	373581	372451	C	ORF, Uncharacterized
5187	S000005077	ORF	Verified	YNL133C	FYV6	14	374692	374171	C	Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining
5189	S000006569	tRNA	n.a.	tF(GAA)N	n.a.	14	374869	374959	W	tRNA-Phe
5190	S000035429	intron	n.a.	n.a.	n.a.	14	374906	374923	W	n.a.
5193	S000005076	ORF	Verified	YNL132W	KRE33	14	375321	378491	W	Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance
5195	S000005075	ORF	Verified	YNL131W	TOM22	14	378767	379225	W	Constituent of the mitochondrial outer membrane translocase complex involved in protein import into mitochondria
5197	S000005074	ORF	Verified	YNL130C	CPT1	14	380831	379558	C	Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription
5200	S000030246	intron	n.a.	n.a.	n.a.	14	380781	380690	C	n.a.
5201	S000028579	ORF	Uncharacterized	YNL130C-A	n.a.	14	381391	381245	C	Identified by fungal homology and RT-PCR
5203	S000005073	ORF	Verified	YNL129W	NRK1	14	381480	382202	W	Nicotinamide riboside kinase, catalyzes the synthesis of nicotinamide nucleotide (NMN) from nicotinamide riboside; involved in a salvage pathway for NAD+ biosynthesis
5205	S000005072	ORF	Verified	YNL128W	TEP1	14	382359	383663	W	Putative phosphatidylinositol phosphate phosphatase, similar to human tumor suppressor gene known as TEP1, MMAC1 and PTEN1
5207	S000005071	ORF	Verified	YNL127W	FAR11	14	383987	386848	W	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p
5209	S000005070	ORF	Verified	YNL126W	SPC98	14	387227	389767	W	Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque
5211	S000005069	ORF	Verified	YNL125C	ESBP6	14	392167	390146	C	Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane
5213	S000005068	ORF	Verified	YNL124W	NAF1	14	392892	394370	W	Protein required for the assembly of box H/ACA snoRNPs and for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; has similarity to Gar1p and other RNA-binding proteins
5215	S000005067	ORF	Uncharacterized	YNL123W	n.a.	14	394685	397678	W	shows protein sequence similarity to the mammalian Omi/HtrA2 family of serine proteases
5217	S000005066	ORF	Uncharacterized	YNL122C	n.a.	14	398370	398023	C	Hypothetical protein
5219	S000005065	ORF	Verified	YNL121C	TOM70	14	400537	398684	C	Translocase of Outer Mitochondrial membrane; 70 kDa mitochondrial specialized import receptor of the outer membrane
5221	S000005063	ORF	Uncharacterized	YNL119W	NCS2	14	401040	402521	W	Protein with a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
5223	S000005064	ORF	Dubious	YNL120C	n.a.	14	401518	401033	C	Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene NCS2
5225	S000005062	ORF	Verified	YNL118C	DCP2	14	405564	402652	C	Protein required for the decapping of mRNAs, functions to allow the production of active Dcp1p, contains a pyrophosphatase MutT motif and several alpha-helical leucine-rich motifs
5227	S000005061	ORF	Verified	YNL117W	MLS1	14	406358	408022	W	Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium
5229	S000005060	ORF	Verified	YNL116W	DMA2	14	408341	409909	W	Protein involved in regulating spindle position and orientation, functionally redundant with Dma1p; homolog of S. pombe Dma1 and H. sapiens Chfr
5231	S000005059	ORF	Uncharacterized	YNL115C	n.a.	14	412053	410119	C	Hypothetical protein
5233	S000005057	ORF	Verified	YNL113W	RPC19	14	412771	413199	W	RNA polymerase subunit, common to RNA polymerases I and III
5235	S000005058	ORF	Dubious	YNL114C	n.a.	14	413055	412684	C	Protein required for cell viability
5237	S000005056	ORF	Verified	YNL112W	DBP2	14	413639	416281	W	Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing
5240	S000033964	intron	n.a.	n.a.	n.a.	14	414912	415913	W	n.a.
5241	S000005055	ORF	Verified	YNL111C	CYB5	14	417302	416940	C	Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; required for sterol C5-6 and fatty acid desaturation
5243	S000005054	ORF	Verified	YNL110C	NOP15	14	418488	417826	C	Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm
5245	S000005053	ORF	Dubious	YNL109W	n.a.	14	418964	419509	W	Hypothetical protein
5247	S000005052	ORF	Uncharacterized	YNL108C	n.a.	14	419826	419014	C	Hypothetical protein
5249	S000005051	ORF	Verified	YNL107W	YAF9	14	420098	420778	W	Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain
5251	S000005049	ORF	Dubious	YNL105W	n.a.	14	424155	424583	W	Hypothetical protein
5253	S000005050	ORF	Verified	YNL106C	INP52	14	424495	420944	C	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in endocytosis; hyperosmotic stress causes translocation to actin patches
5255	S000028701	ORF	Dubious	YNL103W-A	n.a.	14	426719	426808	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5257	S000005048	ORF	Verified	YNL104C	LEU4	14	426754	424895	C	Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway
5259	S000005047	ORF	Verified	YNL103W	MET4	14	427735	429753	W	Lecine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p
5261	S000005046	ORF	Verified	YNL102W	POL1	14	430087	434493	W	Catalytic subunit of the DNA polymerase alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis
5263	S000005045	ORF	Verified	YNL101W	AVT4	14	434999	437140	W	Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
5265	S000005044	ORF	Uncharacterized	YNL100W	n.a.	14	437613	438317	W	Hypothetical protein
5267	S000005043	ORF	Verified	YNL099C	OCA1	14	439283	438567	C	Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA
5269	S000005042	ORF	Verified	YNL098C	RAS2	14	440570	439602	C	GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes
5271	S000028699	ORF	Uncharacterized	YNL097C-B	n.a.	14	440919	440797	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5273	S000028700	ORF	Dubious	YNL097W-A	n.a.	14	441431	441586	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5275	S000005041	ORF	Verified	YNL097C	PHO23	14	442358	441366	C	Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)
5277	S000006645	tRNA	n.a.	tL(CAA)N	n.a.	14	443006	443119	W	tRNA-Leu
5278	S000033817	intron	n.a.	n.a.	n.a.	14	443044	443075	W	n.a.
5281	S000005040	ORF	Verified	YNL096C	RPS7B	14	444315	443398	C	Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Ap; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
5284	S000030168	intron	n.a.	n.a.	n.a.	14	444171	443827	C	n.a.
5285	S000005039	ORF	Uncharacterized	YNL095C	n.a.	14	446840	444912	C	Hypothetical protein
5287	S000005038	ORF	Uncharacterized	YNL094W	APP1	14	447611	449374	W	Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization
5289	S000005037	ORF	Verified	YNL093W	YPT53	14	449868	450530	W	GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis
5291	S000005036	ORF	Uncharacterized	YNL092W	n.a.	14	450871	452073	W	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
5293	S000005035	ORF	Verified	YNL091W	NST1	14	452408	456130	W	Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1
5295	S000005034	ORF	Verified	YNL090W	RHO2	14	456565	457143	W	Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly
5297	S000005033	ORF	Dubious	YNL089C	n.a.	14	457169	456693	C	Hypothetical protein
5299	S000005032	ORF	Verified	YNL088W	TOP2	14	457704	461990	W	Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis
5301	S000005031	ORF	Verified	YNL087W	TCB2	14	462411	465947	W	Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud via the mRNA transport system involving She2p
5303	S000005030	ORF	Uncharacterized	YNL086W	n.a.	14	466334	466642	W	Hypothetical protein
5305	S000005029	ORF	Verified	YNL085W	MKT1	14	467131	469623	W	Protein involved in propagation of M2 dsRNA satellite of L-A virus; forms a complex with Pbp1p that is involved in posttranscriptional regulation of HO endonuclease
5307	S000005028	ORF	Verified	YNL084C	END3	14	471102	470053	C	EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p
5309	S000005027	ORF	Verified	YNL083W	SAL1	14	471377	473014	W	Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains
5311	S000005026	ORF	Verified	YNL082W	PMS1	14	473390	476011	W	ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL
5313	S000005025	ORF	Uncharacterized	YNL081C	SWS2	14	476618	476187	C	Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S13 ribosomal protein
5315	S000005024	ORF	Uncharacterized	YNL080C	n.a.	14	478031	476931	C	Deletion causes slight growth defect, similar to U. maydis myp1 protein
5317	S000005023	ORF	Verified	YNL079C	TPM1	14	479164	478565	C	Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently
5319	S000005022	ORF	Verified	YNL078W	NIS1	14	479767	480990	W	Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network
5321	S000005021	ORF	Verified	YNL077W	APJ1	14	481390	482976	W	Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion
5323	S000005020	ORF	Verified	YNL076W	MKS1	14	483555	485309	W	Pleiotropic regulatory factor involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling
5325	S000005019	ORF	Verified	YNL075W	IMP4	14	485606	486478	W	Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs
5327	S000005018	ORF	Verified	YNL074C	MLF3	14	488123	486765	C	Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide
5329	S000005017	ORF	Verified	YNL073W	MSK1	14	488385	490115	W	Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria
5331	S000005016	ORF	Verified	YNL072W	RNH201	14	490316	491239	W	Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; cooperates with Rad27p nuclease
5333	S000005015	ORF	Verified	YNL071W	LAT1	14	491522	492970	W	Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA
5335	S000005014	ORF	Verified	YNL070W	TOM7	14	493365	493547	W	Involved in mitochondrial protein import; translocase of the outer mito. membrane
5337	S000005013	ORF	Verified	YNL069C	RPL16B	14	495000	493955	C	N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
5340	S000036375	intron	n.a.	n.a.	n.a.	14	494972	494524	C	n.a.
5341	S000005012	ORF	Verified	YNL068C	FKH2	14	498288	495700	C	Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR; potential Cdc28p substrate
5343	S000007623	ORF	Dubious	YNL067W-A	n.a.	14	498537	498683	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
5345	S000028810	ORF	Uncharacterized	YNL067W-B	n.a.	14	499416	499556	W	ORF, Uncharacterized
5347	S000005011	ORF	Verified	YNL067W	RPL9B	14	499680	500255	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins
5349	S000005010	ORF	Verified	YNL066W	SUN4	14	501514	502776	W	Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family
5351	S000005009	ORF	Verified	YNL065W	AQR1	14	503723	505483	W	Plasma membrane transporter of the major facilitator superfamily that confers resistance to short-chain monocarboxylic acids and quinidine
5353	S000005008	ORF	Verified	YNL064C	YDJ1	14	507096	505867	C	Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein translocation across membranes; member of the DnaJ family
5355	S000005007	ORF	Uncharacterized	YNL063W	n.a.	14	507757	508701	W	ORF, Uncharacterized
5357	S000005006	ORF	Verified	YNL062C	GCD10	14	510211	508775	C	Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
5359	S000005005	ORF	Verified	YNL061W	NOP2	14	510539	512395	W	Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles
5361	S000005004	ORF	Verified	YNL059C	ARP5	14	514934	512667	C	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
5363	S000005002	ORF	Dubious	YNL057W	n.a.	14	516402	516734	W	Hypothetical protein
5365	S000005003	ORF	Uncharacterized	YNL058C	n.a.	14	516712	515762	C	Protein of unknown function, localizes to the vacuole; potential Cdc28p substrate
5367	S000005001	ORF	Uncharacterized	YNL056W	n.a.	14	517248	517841	W	Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
5369	S000005000	ORF	Verified	YNL055C	POR1	14	518844	517993	C	Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability
5373	S000006544	tRNA	n.a.	tD(GUC)N	n.a.	14	519168	519098	C	tRNA-Asp
5382	S000004999	ORF	Verified	YNL054W	VAC7	14	526085	529582	W	Integral vacuolar membrane protein involved in vacuole inheritance and morphology; may function to regulate Fab1p kinase activity
5384	S000004998	ORF	Verified	YNL053W	MSG5	14	529941	531410	W	Dual-specificity protein phosphatase required for maintenance of a low level of signaling through the cell integrity pathway; regulates and is regulated by Slt2p; also required for adaptive response to pheromone
5386	S000004997	ORF	Verified	YNL052W	COX5A	14	531724	532185	W	Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth
5388	S000004996	ORF	Verified	YNL051W	COG5	14	532658	533869	W	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
5390	S000004995	ORF	Uncharacterized	YNL050C	n.a.	14	534981	534078	C	Hypothetical protein
5393	S000037524	intron	n.a.	n.a.	n.a.	14	534964	534874	C	n.a.
5394	S000004994	ORF	Verified	YNL049C	SFB2	14	537910	535280	C	Probable component of COPII coated vesicles that binds to Sec23p; similar to and functionally redundant with Sec24p, but expressed at low levels; involved in ER to Golgi transport and in autophagy
5396	S000004993	ORF	Verified	YNL048W	ALG11	14	538172	539818	W	Alpha-1,2-mannosyltransferase, catalyzes addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER
5398	S000004992	ORF	Verified	YNL047C	SLM2	14	541880	539910	C	Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the Tor2p-containing complex TORC2
5400	S000004991	ORF	Uncharacterized	YNL046W	n.a.	14	542303	542821	W	Hypothetical protein
5402	S000004990	ORF	Verified	YNL045W	n.a.	14	542962	544977	W	Leucyl aminopeptidase with epoxide hydrolase activity, metalloenzyme containing one zinc atom; role in vivo is not defined
5404	S000004989	ORF	Verified	YNL044W	YIP3	14	545267	545876	W	Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p
5407	S000035330	intron	n.a.	n.a.	n.a.	14	545291	545369	W	n.a.
5408	S000004988	ORF	Dubious	YNL043C	n.a.	14	545908	545588	C	Hypothetical protein
5412	S000006685	tRNA	n.a.	tP(UGG)N1	n.a.	14	547093	547195	W	tRNA-Pro
5413	S000030970	intron	n.a.	n.a.	n.a.	14	547129	547159	W	n.a.
5416	S000028850	ORF	Uncharacterized	YNL042W-B	n.a.	14	547112	547369	W	Identified by expression profiling and mass spectrometry
5418	S000004987	ORF	Verified	YNL042W	BOP3	14	548099	549289	W	Protein of unknown function, potential Cdc28p substrate; overproduction suppresses a pam1 slv3 double null mutation and confers resistance to methylmercury
5420	S000004986	ORF	Verified	YNL041C	COG6	14	551986	549467	C	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
5422	S000004985	ORF	Uncharacterized	YNL040W	n.a.	14	553379	554749	W	Hypothetical protein
5424	S000004984	ORF	Verified	YNL039W	BDP1	14	555047	556831	W	Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs
5426	S000004983	ORF	Verified	YNL038W	GPI15	14	557019	557782	W	Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein
5429	S000032183	intron	n.a.	n.a.	n.a.	14	557610	557683	W	n.a.
5430	S000004982	ORF	Verified	YNL037C	IDH1	14	559001	557919	C	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
5432	S000004981	ORF	Verified	YNL036W	NCE103	14	559813	560478	W	Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway
5434	S000006745	tRNA	n.a.	tT(AGU)N2	n.a.	14	560764	560692	C	tRNA-Thr
5440	S000006686	tRNA	n.a.	tP(UGG)N2	n.a.	14	568114	568216	W	tRNA-Pro
5441	S000030974	intron	n.a.	n.a.	n.a.	14	568150	568180	W	n.a.
5444	S000004980	ORF	Uncharacterized	YNL035C	n.a.	14	569690	568521	C	Hypothetical protein
5446	S000006609	tRNA	n.a.	tI(AAU)N1	n.a.	14	569939	569866	C	tRNA-Ile
5448	S000004979	ORF	Uncharacterized	YNL034W	n.a.	14	570476	572314	W	Hypothetical protein
5450	S000004978	ORF	Uncharacterized	YNL033W	n.a.	14	572998	573852	W	Hypothetical protein
5452	S000004977	ORF	Verified	YNL032W	SIW14	14	574505	575350	W	Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm
5454	S000004976	ORF	Verified	YNL031C	HHT2	14	576049	575639	C	One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
5456	S000004975	ORF	Verified	YNL030W	HHF2	14	576726	577037	W	One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
5458	S000004973	ORF	Dubious	YNL028W	n.a.	14	578678	578995	W	Hypothetical protein
5460	S000004974	ORF	Verified	YNL029C	KTR5	14	578772	577204	C	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
5462	S000004972	ORF	Verified	YNL027W	CRZ1	14	579579	581615	W	Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation
5464	S000004971	ORF	Verified	YNL026W	SAM50	14	581919	583373	W	Essential component of the Sorting and Assembly Machinery (SAM complex) of the mitochondrial outer membrane; the authentic, non-tagged protein was localized to the mitochondria
5466	S000004970	ORF	Verified	YNL025C	SSN8	14	585290	584319	C	Component of RNA polymerase II holoenzyme, involved in RNA pol II carboxy-terminal domain phosphorylation
5468	S000007436	ncRNA	n.a.	NME1	NME1	14	585586	585925	W	RNA component of RNase MRP, which cleaves pre-rRNA
5470	S000006457	snoRNA	n.a.	snR66	SNR66	14	586089	586174	W	guides 2'-O-methylation on large subunit rRNA at U2415; small nucleolar RNA snR66
5472	S000028698	ORF	Uncharacterized	YNL024C-A	n.a.	14	586819	586601	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5474	S000004969	ORF	Uncharacterized	YNL024C	n.a.	14	587846	587106	C	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
5476	S000004968	ORF	Verified	YNL023C	FAP1	14	591159	588262	C	Protein that binds to Fpr1p (FKBP12), conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; has similarity to putative transcription factors, including D. melanogaster shuttle craft and human NFX1
5478	S000004967	ORF	Uncharacterized	YNL022C	n.a.	14	592898	591426	C	Non-essential protein with similarity to S. pombe hypothetical protein E349594
5480	S000004966	ORF	Verified	YNL021W	HDA1	14	593226	595346	W	Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation
5482	S000004965	ORF	Verified	YNL020C	ARK1	14	597538	595622	C	Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis
5484	S000004964	ORF	Uncharacterized	YNL019C	n.a.	14	599229	598375	C	Hypothetical protein
5486	S000004963	ORF	Uncharacterized	YNL018C	n.a.	14	601773	599935	C	Hypothetical protein
5488	S000006610	tRNA	n.a.	tI(AAU)N2	n.a.	14	602311	602384	W	tRNA-Ile
5490	S000004962	ORF	Dubious	YNL017C	n.a.	14	602475	602137	C	Hypothetical protein
5492	S000004961	ORF	Verified	YNL016W	PUB1	14	602906	604267	W	Poly(A)+ RNA-binding protein, abundant mRNP-component protein hypothesized to bind a pool of non-translatable mRNAs; not reported to associate with polyribosomes
5494	S000004960	ORF	Verified	YNL015W	PBI2	14	605383	605610	W	Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion
5496	S000004959	ORF	Verified	YNL014W	HEF3	14	606318	609452	W	Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells
5498	S000004958	ORF	Dubious	YNL013C	n.a.	14	609509	609132	C	Hypothetical protein
5500	S000004957	ORF	Verified	YNL012W	SPO1	14	609685	611664	W	Meiosis-specific protein with similarity to phospholipase B, required for meiotic spindle pole body duplication and separation; required for spore formation
5503	S000030706	intron	n.a.	n.a.	n.a.	14	609790	609873	W	n.a.
5504	S000004956	ORF	Uncharacterized	YNL011C	n.a.	14	613169	611835	C	Hypothetical protein
5506	S000004955	ORF	Uncharacterized	YNL010W	n.a.	14	613634	614359	W	Hypothetical protein
5508	S000004954	ORF	Verified	YNL009W	IDP3	14	614820	616082	W	Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids
5510	S000004953	ORF	Verified	YNL008C	ASI3	14	618219	616210	C	Putative integral membrane E3 ubiquitin ligase; genetic interactions suggest a role in negative regulation of amino acid uptake
5512	S000004952	ORF	Verified	YNL007C	SIS1	14	619565	618507	C	Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins
5514	S000004951	ORF	Verified	YNL006W	LST8	14	620067	620978	W	Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat
5516	S000004950	ORF	Verified	YNL005C	MRP7	14	622428	621313	C	Mitochondrial ribosomal protein of the large subunit
5518	S000004949	ORF	Verified	YNL004W	HRB1	14	623332	624621	W	Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p
5520	S000004948	ORF	Verified	YNL003C	PET8	14	625829	624975	C	S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth
5522	S000004947	ORF	Verified	YNL002C	RLP7	14	627142	626174	C	Nucleolar protein with similarity to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs
5524	S000004946	ORF	Verified	YNL001W	DOM34	14	627456	628616	W	Probable RNA-binding protein, functions in protein translation to promote G1 progression and differentiation, required for meiotic cell division
5530	S000005284	ORF	Verified	YNR001C	CIT1	14	631061	629622	C	Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein
5532	S000007625	ORF	Dubious	YNR001W-A	n.a.	14	631263	631481	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
5534	S000006679	tRNA	n.a.	tP(AGG)N	SUF10	14	631917	631846	C	tRNA-Pro
5538	S000006674	tRNA	n.a.	tN(GUU)N2	n.a.	14	632599	632672	W	tRNA-Asn
5540	S000005285	ORF	Verified	YNR002C	FUN34	14	633856	633008	C	Putative transmembrane protein, involved in ammonia production; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p
5542	S000028705	ORF	Dubious	YNR003W-A	n.a.	14	634420	634518	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5544	S000005286	ORF	Verified	YNR003C	RPC34	14	635297	634344	C	RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex
5546	S000005287	ORF	Uncharacterized	YNR004W	n.a.	14	635943	636383	W	Hypothetical protein
5548	S000005289	ORF	Verified	YNR006W	VPS27	14	636986	638854	W	Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)
5550	S000005288	ORF	Dubious	YNR005C	n.a.	14	637335	636931	C	Hypothetical protein
5552	S000005290	ORF	Verified	YNR007C	ATG3	14	640114	639182	C	Protein involved in autophagy; E2-like enzyme that plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy
5554	S000005291	ORF	Verified	YNR008W	LRO1	14	640396	642381	W	Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; putative homolog of human lecithin cholesterol acyltransferase
5556	S000005292	ORF	Uncharacterized	YNR009W	n.a.	14	642690	643439	W	Hypothetical protein
5558	S000005293	ORF	Verified	YNR010W	CSE2	14	643744	644193	W	Component of the Med9/10 module, which is a subcomplex within the RNA polymerase II Mediator complex; required for regulation of RNA polymerase II activity
5560	S000005294	ORF	Verified	YNR011C	PRP2	14	646950	644320	C	RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing
5562	S000005295	ORF	Verified	YNR012W	URK1	14	647432	648937	W	Uridine/cytidine kinase, component of the pyrimidine ribonucleotide salvage pathway that converts uridine into UMP and cytidine into CMP; involved in the pyrimidine deoxyribonucleotide salvage pathway, converting deoxycytidine into dCMP
5564	S000005296	ORF	Verified	YNR013C	PHO91	14	651712	649028	C	Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth
5566	S000005297	ORF	Uncharacterized	YNR014W	n.a.	14	652465	653103	W	Hypothetical protein
5568	S000005298	ORF	Verified	YNR015W	SMM1	14	653387	654541	W	Dihydrouridine synthase, member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs
5570	S000005299	ORF	Verified	YNR016C	ACC1	14	661374	654673	C	Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids
5572	S000005300	ORF	Verified	YNR017W	MAS6	14	662913	663581	W	Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system
5574	S000005301	ORF	Uncharacterized	YNR018W	n.a.	14	664270	664944	W	Hypothetical protein
5576	S000005302	ORF	Verified	YNR019W	ARE2	14	665339	667267	W	Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen
5578	S000005303	ORF	Uncharacterized	YNR020C	n.a.	14	668222	667410	C	Hypothetical protein
5580	S000005304	ORF	Uncharacterized	YNR021W	n.a.	14	668377	669591	W	Hypothetical protein
5582	S000005305	ORF	Verified	YNR022C	MRPL50	14	670193	669774	C	Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation
5584	S000005306	ORF	Verified	YNR023W	SNF12	14	670418	672118	W	73 kDa subunit of the 11-subunit SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive
5586	S000005307	ORF	Uncharacterized	YNR024W	n.a.	14	672409	672969	W	Hypothetical protein
5588	S000005308	ORF	Dubious	YNR025C	n.a.	14	673061	672702	C	Hypothetical protein
5590	S000005309	ORF	Verified	YNR026C	SEC12	14	674689	673274	C	Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein of the endoplasmic reticulum, important for the initiation of transport vesicle budding from the endoplasmic reticulum through activation of the GTPase Sar1p
5592	S000005310	ORF	Verified	YNR027W	BUD17	14	674923	675876	W	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
5594	S000005311	ORF	Verified	YNR028W	CPR8	14	676177	677103	W	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; similarity to Cpr4p suggests a potential role in the secretory pathway
5596	S000005312	ORF	Uncharacterized	YNR029C	n.a.	14	678488	677199	C	Hypothetical protein
5598	S000005313	ORF	Verified	YNR030W	ALG12	14	678799	680454	W	Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation
5600	S000005314	ORF	Verified	YNR031C	SSK2	14	685433	680694	C	MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress
5602	S000005315	ORF	Verified	YNR032W	PPG1	14	686010	687116	W	Putative serine/threonine protein phosphatase, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases
5604	S000007251	ORF	Verified	YNR032C-A	HUB1	14	687464	687243	C	Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear
5606	S000005316	ORF	Verified	YNR033W	ABZ1	14	687635	689998	W	Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB
5608	S000005317	ORF	Verified	YNR034W	SOL1	14	690321	691286	W	Protein with a possible role in tRNA export; shows similarity to glucose-6-phosphate dehydrogenase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p
5610	S000007525	ORF	Uncharacterized	YNR034W-A	n.a.	14	692561	692857	W	Hypothetical protein
5612	S000005318	ORF	Verified	YNR035C	ARC35	14	694047	693019	C	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin
5614	S000005319	ORF	Uncharacterized	YNR036C	n.a.	14	694822	694361	C	Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli and human mitochondrial S12 ribosomal proteins
5616	S000005320	ORF	Verified	YNR037C	RSM19	14	695327	695052	C	Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S19 ribosomal protein
5618	S000005321	ORF	Verified	YNR038W	DBP6	14	695595	697484	W	Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family
5620	S000005322	ORF	Verified	YNR039C	ZRG17	14	699431	697614	C	Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc deficiency; mutant phenotype suggests a role in uptake of zinc
5622	S000005323	ORF	Uncharacterized	YNR040W	n.a.	14	699690	700460	W	Hypothetical protein
5624	S000005325	ORF	Dubious	YNR042W	n.a.	14	701238	701666	W	Hypothetical protein
5626	S000005324	ORF	Verified	YNR041C	COQ2	14	701659	700541	C	Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis
5628	S000005326	ORF	Verified	YNR043W	MVD1	14	701895	703085	W	Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer
5630	S000005327	ORF	Verified	YNR044W	AGA1	14	703699	705876	W	Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds
5632	S000005328	ORF	Verified	YNR045W	PET494	14	706139	707608	W	Specific translational activator for the COX3 mRNA that acts together with Pet54p and Pet122p; located in the mitochondrial inner membrane
5634	S000005329	ORF	Verified	YNR046W	TRM112	14	707788	708195	W	Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; putative zinc binding subunit of other MTase-related proteins
5636	S000005330	ORF	Uncharacterized	YNR047W	n.a.	14	708523	711204	W	Putative protein kinase that, when overexpressed, interferes with pheromone-induced growth arrest; localizes to the cytoplasm; potential Cdc28p substrate
5638	S000005331	ORF	Uncharacterized	YNR048W	n.a.	14	711630	712811	W	Protein with similarity to Cdc50p
5640	S000005332	ORF	Verified	YNR049C	MSO1	14	713655	713023	C	Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows genetic and physical interactions with Sec1p and is enriched in microsomal membrane fractions; required for sporulation
5642	S000005333	ORF	Verified	YNR050C	LYS9	14	715388	714048	C	Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, which is the seventh step in lysine biosynthesis pathway
5644	S000007460	snoRNA	n.a.	snR49	SNR49	14	716120	716284	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of small subunit rRNA at positions 120, 211, and 302 and of large subunit rRNA at position 989
5646	S000005334	ORF	Verified	YNR051C	BRE5	14	718327	716780	C	Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A
5648	S000005335	ORF	Verified	YNR052C	POP2	14	720647	719346	C	RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation
5650	S000029463	snoRNA	n.a.	snR191	SNR191	14	722210	721937	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at positions 2259 and 2257; encoded within the intron of NOG2/YNR053C
5652	S000005336	ORF	Verified	YNR053C	NOG2	14	723111	721120	C	Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation
5655	S000033759	intron	n.a.	n.a.	n.a.	14	722301	721771	C	n.a.
5656	S000005337	ORF	Uncharacterized	YNR054C	n.a.	14	724305	723355	C	Essential protein of unknown function, has homology to mouse mABT1, which is a basal transcription activator that associates with TBP
5658	S000006653	tRNA	n.a.	tL(UAA)N	n.a.	14	726216	726133	C	tRNA-Leu
5663	S000005338	ORF	Verified	YNR055C	HOL1	14	730185	728425	C	Putative ion transporter similar to the major facilitator superfamily of transporters; mutations in membrane-spanning domains permit nonselective cation uptake
5665	S000005339	ORF	Verified	YNR056C	BIO5	14	733301	731616	C	Putative transmembrane protein involved in the biotin biosynthesis pathway; responsible for uptake of 7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis
5667	S000005340	ORF	Verified	YNR057C	BIO4	14	734067	733354	C	Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels
5669	S000005341	ORF	Verified	YNR058W	BIO3	14	734289	735731	W	7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis
5671	S000005342	ORF	Verified	YNR059W	MNT4	14	736801	738543	W	Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation
5673	S000005343	ORF	Verified	YNR060W	FRE4	14	739949	742108	W	Ferric reductase, reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels
5675	S000005344	ORF	Uncharacterized	YNR061C	n.a.	14	743538	742879	C	Hypothetical protein
5677	S000005345	ORF	Uncharacterized	YNR062C	n.a.	14	745341	744358	C	Hypothetical protein
5679	S000005346	ORF	Uncharacterized	YNR063W	n.a.	14	746941	748764	W	Hypothetical protein
5681	S000005347	ORF	Verified	YNR064C	n.a.	14	750006	749134	C	Epoxide hydrolase, member of the alpha/beta hydrolase fold family; may have a role in detoxification of epoxides
5683	S000005348	ORF	Uncharacterized	YNR065C	n.a.	14	753698	750348	C	Sortilin homolog, interacts with proteins of the endocytic machinery
5685	S000005349	ORF	Uncharacterized	YNR066C	n.a.	14	755033	753723	C	Hypothetical protein
5687	S000005350	ORF	Verified	YNR067C	DSE4	14	759097	755744	C	Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother
5689	S000005351	ORF	Uncharacterized	YNR068C	n.a.	14	760883	760065	C	Hypothetical protein
5691	S000005352	ORF	Verified	YNR069C	BSC5	14	762590	761121	C	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
5693	S000005353	ORF	Uncharacterized	YNR070W	n.a.	14	765373	769374	W	Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resistance
5695	S000005354	ORF	Uncharacterized	YNR071C	n.a.	14	771466	770438	C	Hypothetical protein
5697	S000005355	ORF	Verified	YNR072W	HXT17	14	772655	774349	W	Protein of unknown function with similarity to hexose transporter family members, expression is repressed by high levels of glucose
5699	S000005356	ORF	Uncharacterized	YNR073C	n.a.	14	776298	774790	C	Hypothetical protein
5701	S000005357	ORF	Verified	YNR074C	AIF1	14	778736	777600	C	Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase
5703	S000005358	ORF	Verified	YNR075W	COS10	14	779914	781038	W	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
5705	S000028706	ORF	Uncharacterized	YNR075C-A	n.a.	14	781601	781509	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5707	S000005359	ORF	Verified	YNR076W	PAU6	14	781916	782278	W	Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
5713	S000005360	ORF	Dubious	YNR077C	n.a.	14	783539	783285	C	Hypothetical protein
5720	S000028709	ORF	Uncharacterized	YOL166W-A	n.a.	15	585	740	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5725	S000005526	ORF	Dubious	YOL166C	n.a.	15	1338	1000	C	Hypothetical protein
5727	S000005525	ORF	Verified	YOL165C	AAD15	15	2078	1647	C	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
5731	S000028580	ORF	Uncharacterized	YOL164W-A	n.a.	15	4130	4312	W	Identified by fungal homology and RT-PCR
5733	S000005524	ORF	Uncharacterized	YOL164W	n.a.	15	6175	8115	W	Bacterially-derived sulfatase required for use of alkyl- and aryl-sulfates as sulfur sources
5735	S000005523	ORF	Uncharacterized	YOL163W	n.a.	15	9596	10105	W	Hypothetical protein, member of the Dal5p subfamily of the major facilitator family
5737	S000005522	ORF	Uncharacterized	YOL162W	n.a.	15	10118	10765	W	Hypothetical protein, member of the Dal5p subfamily of the major facilitator family
5739	S000005521	ORF	Uncharacterized	YOL161C	n.a.	15	11910	11548	C	Hypothetical protein
5741	S000005520	ORF	Dubious	YOL160W	n.a.	15	14312	14653	W	Hypothetical protein
5743	S000007627	ORF	Uncharacterized	YOL159C-A	n.a.	15	15504	15232	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
5745	S000005519	ORF	Uncharacterized	YOL159C	n.a.	15	17795	17280	C	Hypothetical protein
5748	S000005518	ORF	Verified	YOL158C	ENB1	15	21310	19490	C	Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment
5750	S000005517	ORF	Uncharacterized	YOL157C	n.a.	15	24293	22524	C	Hypothetical protein
5752	S000005516	ORF	Verified	YOL156W	HXT11	15	25272	26975	W	Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance
5754	S000028855	ORF	Uncharacterized	YOL155W-A	n.a.	15	27083	27217	W	Identified by expression profiling and mass spectrometry
5756	S000005515	ORF	Uncharacterized	YOL155C	n.a.	15	31605	28702	C	ORF
5758	S000005514	ORF	Verified	YOL154W	ZPS1	15	34657	35406	W	Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH
5762	S000005512	ORF	Verified	YOL152W	FRE7	15	40747	42636	W	Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels but not by low iron levels
5764	S000005511	ORF	Verified	YOL151W	GRE2	15	43692	44720	W	NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
5766	S000005510	ORF	Dubious	YOL150C	n.a.	15	44782	44471	C	Hypothetical protein
5768	S000005509	ORF	Verified	YOL149W	DCP1	15	44936	45631	W	Decapping enzyme, essential phosphoprotein component of mRNA decapping complex, plays key role in mRNA decay by cleaving off the 5' cap to leave the end susceptible to exonucleolytic degradation; regulated by DEAD box protein Dhh1p
5770	S000005508	ORF	Verified	YOL148C	SPT20	15	47572	45758	C	Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex
5772	S000005507	ORF	Verified	YOL147C	PEX11	15	48641	47931	C	Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation, most abundant protein in the peroxisomal membrane, regulated by Adr1p and Pip2p-Oaf1p, promoter contains ORE and UAS1-like elements
5774	S000005506	ORF	Verified	YOL146W	PSF3	15	48862	49446	W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
5776	S000005505	ORF	Verified	YOL145C	CTR9	15	52786	49553	C	Component of the Paf1p complex, which is a large complex that binds to and modulates the activity of RNA polymerase II and is required for expression of a subset of genes, including cyclin genes; contains TPR repeats
5778	S000005504	ORF	Verified	YOL144W	NOP8	15	53096	54550	W	Nucleolar protein required for 60S ribosomal subunit biogenesis
5780	S000005503	ORF	Verified	YOL143C	RIB4	15	55102	54593	C	Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin
5782	S000005502	ORF	Verified	YOL142W	RRP40	15	55556	56278	W	Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex
5784	S000005501	ORF	Verified	YOL141W	PPM2	15	56450	58537	W	Putative carboxyl methyl transferase, has similarity to Ppm1p but biochemical activity not yet demonstrated
5786	S000005500	ORF	Verified	YOL140W	ARG8	15	58758	60029	W	Acetylornithine aminotransferase, catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine
5788	S000005499	ORF	Verified	YOL139C	CDC33	15	61023	60382	C	Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p)
5790	S000005498	ORF	Uncharacterized	YOL138C	n.a.	15	65349	61324	C	Hypothetical protein
5792	S000005497	ORF	Verified	YOL137W	BSC6	15	65620	67113	W	Protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
5794	S000005496	ORF	Verified	YOL136C	PFK27	15	68753	67560	C	6-phosphofructo-2-kinase, has negligible fructose-2,6-bisphosphatase activity, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A
5796	S000005495	ORF	Verified	YOL135C	MED7	15	70043	69375	C	Member of RNA Polymerase II transcriptional regulation mediator; Stoichiometric member of mediator complex
5798	S000005493	ORF	Verified	YOL133W	HRT1	15	70324	70689	W	RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF
5800	S000005494	ORF	Dubious	YOL134C	n.a.	15	70544	70155	C	Protein required for cell viability
5802	S000005492	ORF	Verified	YOL132W	GAS4	15	71299	72714	W	Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
5804	S000005491	ORF	Uncharacterized	YOL131W	n.a.	15	73030	73356	W	Hypothetical protein
5806	S000005490	ORF	Verified	YOL130W	ALR1	15	74399	76978	W	Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions
5808	S000005489	ORF	Verified	YOL129W	VPS68	15	77559	78113	W	Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria
5810	S000005488	ORF	Verified	YOL128C	YGK3	15	79478	78351	C	Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation
5812	S000005487	ORF	Verified	YOL127W	RPL25	15	80347	81189	W	Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif
5815	S000031097	intron	n.a.	n.a.	n.a.	15	80360	80773	W	n.a.
5816	S000005486	ORF	Verified	YOL126C	MDH2	15	83057	81786	C	Cytoplasmic malate dehydrogenase, one of the three isozymes that catalyze interconversion of malate and oxaloacetate; involved in gluconeogenesis during growth on ethanol or acetate as carbon source; interacts with Pck1p and Fbp1p
5818	S000005485	ORF	Uncharacterized	YOL125W	n.a.	15	83833	85263	W	Hypothetical protein
5820	S000005484	ORF	Verified	YOL124C	TRM11	15	86756	85455	C	Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain
5822	S000005483	ORF	Verified	YOL123W	HRP1	15	87843	89447	W	Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences
5824	S000005482	ORF	Verified	YOL122C	SMF1	15	91418	89691	C	Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins
5826	S000005481	ORF	Verified	YOL121C	RPS19A	15	92849	92025	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps19Bp and has similarity to rat S19 ribosomal protein
5829	S000035839	intron	n.a.	n.a.	n.a.	15	92829	92440	C	n.a.
5830	S000005480	ORF	Verified	YOL120C	RPL18A	15	94401	93394	C	Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and has similarity to rat L18 ribosomal protein; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation
5833	S000035728	intron	n.a.	n.a.	n.a.	15	94289	93843	C	n.a.
5834	S000005479	ORF	Verified	YOL119C	MCH4	15	96360	94855	C	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
5836	S000005478	ORF	Dubious	YOL118C	n.a.	15	96915	96607	C	Hypothetical protein
5838	S000005477	ORF	Verified	YOL117W	RRI2	15	97550	99487	W	Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response
5840	S000005476	ORF	Verified	YOL116W	MSN1	15	99808	100956	W	Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus
5842	S000005475	ORF	Verified	YOL115W	PAP2	15	101474	103228	W	Catalytic subunit of TRAMP (Trf4/Pap2p-Mtr4p-Air1p/2p), a nuclear poly (A) polymerase complex involved in RNA quality control; catalyzes polyadenylation of unmodified tRNAs, and snoRNA and rRNA precursors; disputed role as a DNA polymerase
5844	S000005474	ORF	Uncharacterized	YOL114C	n.a.	15	103924	103316	C	Hypothetical protein
5846	S000005473	ORF	Verified	YOL113W	SKM1	15	104325	106292	W	Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; proposed to be a downstream effector of Cdc42p during polarized growth
5848	S000005472	ORF	Verified	YOL112W	MSB4	15	106709	108187	W	GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization
5850	S000005471	ORF	Uncharacterized	YOL111C	n.a.	15	108895	108257	C	Hypothetical protein
5852	S000005470	ORF	Verified	YOL110W	SHR5	15	109175	109888	W	Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to Ras2p through a thioester linkage; palmitoylation is required for Ras2p localization to the plasma membrane
5854	S000005469	ORF	Verified	YOL109W	ZEO1	15	110296	110637	W	Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p
5856	S000006592	tRNA	n.a.	tG(UCC)O	SUF1	15	111032	110961	C	tRNA-Gly
5858	S000005468	ORF	Verified	YOL108C	INO4	15	111885	111430	C	Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain
5860	S000005467	ORF	Uncharacterized	YOL107W	n.a.	15	112101	113129	W	Hypothetical protein
5862	S000005466	ORF	Dubious	YOL106W	n.a.	15	113225	113578	W	Hypothetical protein
5865	S000006746	tRNA	n.a.	tT(AGU)O1	n.a.	15	113801	113873	W	tRNA-Thr
5867	S000005465	ORF	Verified	YOL105C	WSC3	15	115807	114137	C	cell wall integrity and stress response component 3; Putative integral membrane protein containing novel cysteine motif. Similarity to SLG1 (WSC1), WSC2 and WSC4
5869	S000005464	ORF	Verified	YOL104C	NDJ1	15	117453	116395	C	Meiosis-specific telomere protein, required for bouquet formation, effective homolog pairing, ordered cross-over distribution (interference), sister chromatid cohesion at meiotic telomeres, and segregation of small chromosomes
5880	S000005463	ORF	Verified	YOL103W	ITR2	15	124000	125829	W	Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively
5882	S000005462	ORF	Verified	YOL102C	TPT1	15	126688	125996	C	tRNA 2'-phosphotransferase, catalyzes the final step in yeast tRNA splicing: the transfer of the 2'-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1''-2''cyclic phosphate and nicotinamide
5884	S000005461	ORF	Verified	YOL101C	IZH4	15	127919	126981	C	Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism
5886	S000005460	ORF	Verified	YOL100W	PKH2	15	129236	132481	W	Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p
5888	S000005459	ORF	Dubious	YOL099C	n.a.	15	132507	132016	C	Hypothetical protein
5890	S000005458	ORF	Uncharacterized	YOL098C	n.a.	15	135837	132724	C	Putative metalloprotease
5892	S000006449	snoRNA	n.a.	snR58	SNR58	15	136182	136087	C	guides 2'-O-methylation on large subunit ribosomal RNA at C661; small nucleolar RNA snR58
5894	S000028854	ORF	Uncharacterized	YOL097W-A	n.a.	15	136219	136404	W	Identified by expression profiling and mass spectrometry
5896	S000005457	ORF	Verified	YOL097C	WRS1	15	137824	136526	C	Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA
5898	S000005456	ORF	Verified	YOL096C	COQ3	15	139044	138106	C	O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex
5900	S000005455	ORF	Verified	YOL095C	HMI1	15	141346	139226	C	Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription
5902	S000005454	ORF	Verified	YOL094C	RFC4	15	142554	141583	C	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
5904	S000005453	ORF	Verified	YOL093W	TRM10	15	142814	143695	W	tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs
5906	S000005452	ORF	Uncharacterized	YOL092W	n.a.	15	144203	145129	W	Hypothetical protein
5908	S000005451	ORF	Verified	YOL091W	SPO21	15	145333	147162	W	Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation
5910	S000005450	ORF	Verified	YOL090W	MSH2	15	147381	150275	W	Protein that forms heterodimers, with Msh3p and Msh6p, that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP
5912	S000005449	ORF	Verified	YOL089C	HAL9	15	153489	150397	C	Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression
5914	S000005448	ORF	Verified	YOL088C	MPD2	15	154744	153911	C	Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p
5916	S000005447	ORF	Uncharacterized	YOL087C	n.a.	15	158636	155286	C	Hypothetical protein
5918	S000007626	ORF	Uncharacterized	YOL086W-A	n.a.	15	159172	159444	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
5920	S000005446	ORF	Verified	YOL086C	ADH1	15	160593	159547	C	Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway
5922	S000028708	ORF	Dubious	YOL085W-A	n.a.	15	161578	161790	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
5924	S000005445	ORF	Dubious	YOL085C	n.a.	15	162013	161672	C	Hypothetical protein
5926	S000005444	ORF	Verified	YOL084W	PHM7	15	162355	165330	W	Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
5928	S000005443	ORF	Uncharacterized	YOL083W	n.a.	15	165713	166951	W	Hypothetical protein
5930	S000028853	ORF	Dubious	YOL083C-A	n.a.	15	166600	166460	C	Identified by expression profiling and mass spectrometry
5932	S000005442	ORF	Verified	YOL082W	ATG19	15	168726	169973	W	Protein involved in the cytoplasm-to-vacuole targeting pathway and in autophagy, recognizes cargo proteins and delivers them to the preautophagosomal structure for eventual engulfment by the autophagosome and degradation
5934	S000005441	ORF	Verified	YOL081W	IRA2	15	171069	180308	W	GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin
5936	S000005439	ORF	Dubious	YOL079W	n.a.	15	181056	181454	W	Hypothetical protein
5938	S000005440	ORF	Verified	YOL080C	REX4	15	181426	180557	C	Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly
5940	S000005438	ORF	Verified	YOL078W	AVO1	15	181681	185211	W	Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth
5942	S000007339	ORF	Verified	YOL077W-A	ATP19	15	185437	185643	W	Subunit k of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase
5944	S000005437	ORF	Verified	YOL077C	BRX1	15	186722	185847	C	Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif
5946	S000005436	ORF	Verified	YOL076W	MDM20	15	187023	189413	W	Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met; involved in mitochondrial inheritance and actin assembly
5948	S000005435	ORF	Uncharacterized	YOL075C	n.a.	15	193541	189657	C	Hypothetical protein
5950	S000005434	ORF	Uncharacterized	YOL073C	n.a.	15	194799	193831	C	Hypothetical protein
5952	S000005433	ORF	Verified	YOL072W	THP1	15	194969	196336	W	Nuclear pore-associated protein, forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding
5954	S000005432	ORF	Verified	YOL071W	EMI5	15	196506	196994	W	Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation
5956	S000005431	ORF	Uncharacterized	YOL070C	n.a.	15	198724	197219	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, and bud neck; potential Cdc28p substrate
5958	S000005430	ORF	Verified	YOL069W	NUF2	15	198941	200296	W	Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
5960	S000005429	ORF	Verified	YOL068C	HST1	15	201878	200367	C	NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing at HMR and for mitotic repression of mid-sporulation genes; non-essential subunit of the Set3C deacetylase complex
5962	S000005428	ORF	Verified	YOL067C	RTG1	15	202517	201984	C	Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus
5964	S000005427	ORF	Verified	YOL066C	RIB2	15	204470	202695	C	DRAP deaminase, catalyzes the third step of the riboflavin biosynthesis pathway; N-terminus has sequence similarity to RNA:pseudouridine synthases
5966	S000005426	ORF	Verified	YOL065C	INP54	15	205884	204730	C	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins
5968	S000005425	ORF	Verified	YOL064C	MET22	15	207175	206102	C	Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway
5970	S000005424	ORF	Uncharacterized	YOL063C	n.a.	15	210264	207391	C	Protein of unknown function; not related to the HUS1 checkpoint protein identified in human and fission yeast
5972	S000005423	ORF	Verified	YOL062C	APM4	15	211994	210519	C	Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport
5974	S000005422	ORF	Verified	YOL061W	PRS5	15	212243	213733	W	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes
5976	S000005421	ORF	Verified	YOL060C	MAM3	15	216136	214016	C	Protein required for normal mitochondrial morphology, has similarity to hemolysins
5978	S000005420	ORF	Verified	YOL059W	GPD2	15	217125	218447	W	NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria
5980	S000005419	ORF	Verified	YOL058W	ARG1	15	219209	220471	W	Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate
5982	S000005418	ORF	Uncharacterized	YOL057W	n.a.	15	220765	222900	W	Putative metalloprotease
5984	S000005417	ORF	Verified	YOL056W	GPM3	15	223266	224177	W	Homolog of Gpm1p phosphoglycerate mutase which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event
5986	S000005416	ORF	Verified	YOL055C	THI20	15	226073	224418	C	Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI21 and THI22; functionally redundant with Thi21p
5988	S000006586	tRNA	n.a.	tG(GCC)O1	n.a.	15	226679	226609	C	tRNA-Gly
5993	S000006675	tRNA	n.a.	tN(GUU)O1	n.a.	15	228329	228402	W	tRNA-Asn
5995	S000005415	ORF	Uncharacterized	YOL054W	n.a.	15	228612	229832	W	Nuclear protein, putative RNA polymerase II elongation factor; isolated as Pob3p/Spt16p-binding protein
5997	S000005414	ORF	Uncharacterized	YOL053W	n.a.	15	230083	231270	W	Hypothetical protein
5999	S000005413	ORF	Verified	YOL052C-A	DDR2	15	231753	231568	C	Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses
6001	S000005412	ORF	Verified	YOL052C	SPE2	15	233634	232444	C	S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically
6003	S000005411	ORF	Verified	YOL051W	GAL11	15	234938	238183	W	Component of the Mediator complex; interacts with RNA polymerase II and the general transcription factors to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors
6005	S000005410	ORF	Dubious	YOL050C	n.a.	15	238200	237880	C	Hypothetical protein
6007	S000005409	ORF	Verified	YOL049W	GSH2	15	238617	240092	W	Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock
6009	S000005408	ORF	Uncharacterized	YOL048C	n.a.	15	241308	240202	C	Hypothetical protein
6012	S000036369	intron	n.a.	n.a.	n.a.	15	241023	240946	C	n.a.
6013	S000005407	ORF	Uncharacterized	YOL047C	n.a.	15	242745	241612	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
6016	S000036271	intron	n.a.	n.a.	n.a.	15	242502	242440	C	n.a.
6017	S000005405	ORF	Verified	YOL045W	PSK2	15	243495	246800	W	One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation)
6019	S000005406	ORF	Dubious	YOL046C	n.a.	15	244138	243464	C	Hypothetical protein
6021	S000005404	ORF	Verified	YOL044W	PEX15	15	247148	248299	W	Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly
6023	S000005403	ORF	Verified	YOL043C	NTG2	15	249532	248390	C	DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus
6025	S000005402	ORF	Verified	YOL042W	NGL1	15	249823	250914	W	Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p
6027	S000005401	ORF	Verified	YOL041C	NOP12	15	252644	251265	C	Nucleolar protein, required for pre-25S rRNA processing; contains an RNA recognition motif (RRM) and has similarity to Nop13p, Nsr1p, and putative orthologs in Drosophila and S. pombe
6029	S000005400	ORF	Verified	YOL040C	RPS15	15	253575	253147	C	Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins
6031	S000005399	ORF	Verified	YOL039W	RPP2A	15	254295	254615	W	Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
6033	S000028812	ORF	Uncharacterized	YOL038C-A	n.a.	15	255019	254924	C	Identified by SAGE
6035	S000005398	ORF	Verified	YOL038W	PRE6	15	255335	256099	W	20S proteasome alpha-type subunit
6037	S000005396	ORF	Uncharacterized	YOL036W	n.a.	15	256743	259028	W	Protein of unknown function; potential Cdc28p substrate
6039	S000005397	ORF	Dubious	YOL037C	n.a.	15	257017	256664	C	Hypothetical protein
6041	S000005395	ORF	Dubious	YOL035C	n.a.	15	259103	258801	C	Hypothetical protein
6043	S000006441	snoRNA	n.a.	snR50	SNR50	15	259489	259578	W	guides 2'-O-methylation on large subunit rRNA at G865; small nucleolar RNA snR50
6045	S000005394	ORF	Verified	YOL034W	SMC5	15	259923	263204	W	Structural maintenance of chromosomes (SMC) protein, interacts with Smc6p and Nse1p to form a large complex; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair
6047	S000005393	ORF	Verified	YOL033W	MSE1	15	263475	265085	W	Mitochondrial glutamyl-tRNA synthetase, encoded by a nuclear gene
6049	S000005392	ORF	Uncharacterized	YOL032W	n.a.	15	265429	266169	W	Hypothetical protein
6051	S000005391	ORF	Verified	YOL031C	SIL1	15	267529	266264	C	Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein
6053	S000005390	ORF	Verified	YOL030W	GAS5	15	268187	269641	W	Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall
6055	S000005389	ORF	Uncharacterized	YOL029C	n.a.	15	270420	269815	C	Hypothetical protein
6057	S000005388	ORF	Verified	YOL028C	YAP7	15	271370	270633	C	Putative basic leucine zipper (bZIP) transcription factor
6059	S000005387	ORF	Verified	YOL027C	MDM38	15	273724	272003	C	Mitochondrial inner membrane protein, required for mitochondrial potassium homeostasis and for normal mitochondrial morphology and inheritance; human ortholog is implicated in Wolf-Hirschhorn syndrome
6061	S000005386	ORF	Verified	YOL026C	MIM1	15	274353	274012	C	Mitochondrial outer membrane protein, required for assembly of the translocase of the outer membrane (TOM) complex and thereby for mitochondrial protein import; N terminus is exposed to the cytosol: transmembrane segment is highly conserved
6063	S000006733	tRNA	n.a.	tS(GCU)O	n.a.	15	274673	274773	W	tRNA-Ser
6064	S000037500	intron	n.a.	n.a.	n.a.	15	274710	274728	W	n.a.
6067	S000005385	ORF	Verified	YOL025W	LAG2	15	274957	276939	W	Protein involved in determination of longevity; LAG2 gene is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells
6069	S000005384	ORF	Uncharacterized	YOL024W	n.a.	15	277086	277604	W	Hypothetical protein
6071	S000005383	ORF	Verified	YOL023W	IFM1	15	278056	280086	W	Mitochondrial translation initiation factor 2
6073	S000005382	ORF	Uncharacterized	YOL022C	n.a.	15	281498	280272	C	Protein required for cell viability
6075	S000006587	tRNA	n.a.	tG(GCC)O2	SUF17	15	282164	282234	W	tRNA-Gly
6077	S000005381	ORF	Verified	YOL021C	DIS3	15	285426	282421	C	Nucleolar exosome component, involved in rRNA processing and RNA degradation, binds Gsp1p/Ran and enhances the GEF activity of Srm1p, implicated in mitotic control, homologous to the E. coli RNase R of the RNase II family
6079	S000005380	ORF	Verified	YOL020W	TAT2	15	286172	287950	W	High affinity tryptophan and tyrosine permease, overexpression confers FK506 resistance
6081	S000006785	tRNA	n.a.	tY(GUA)O	SUP3	15	288192	288280	W	tRNA-Tyr
6082	S000034708	intron	n.a.	n.a.	n.a.	15	288231	288244	W	n.a.
6085	S000028707	ORF	Uncharacterized	YOL019W-A	n.a.	15	288420	288572	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6087	S000005379	ORF	Uncharacterized	YOL019W	n.a.	15	288898	290553	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole
6089	S000005378	ORF	Verified	YOL018C	TLG2	15	292074	290881	C	Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation
6091	S000005377	ORF	Verified	YOL017W	ESC8	15	292529	294673	W	Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex
6093	S000005376	ORF	Verified	YOL016C	CMK2	15	296120	294777	C	Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk1p and mammalian Cam Kinase II
6095	S000005375	ORF	Uncharacterized	YOL015W	n.a.	15	297078	298838	W	Hypothetical protein
6097	S000005374	ORF	Uncharacterized	YOL014W	n.a.	15	299693	300067	W	Hypothetical protein
6099	S000007252	ORF	Dubious	YOL013W-B	n.a.	15	300690	300980	W	Similar to probable membrane protein YLR334C and ORF YOL106W
6102	S000028811	ORF	Uncharacterized	YOL013W-A	n.a.	15	301047	301238	W	Identified by SAGE
6104	S000006687	tRNA	n.a.	tP(UGG)O1	n.a.	15	301097	301198	W	tRNA-Pro
6105	S000031042	intron	n.a.	n.a.	n.a.	15	301133	301162	W	n.a.
6108	S000005373	ORF	Verified	YOL013C	HRD1	15	303035	301380	C	Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger
6110	S000005372	ORF	Verified	YOL012C	HTZ1	15	303983	303579	C	Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin
6112	S000005371	ORF	Verified	YOL011W	PLB3	15	305349	307409	W	Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro
6114	S000005370	ORF	Verified	YOL010W	RCL1	15	307938	309041	W	RNA terminal phosphate cyclase-like protein involved in rRNA processing at sites A0, A1, and A2; does not possess detectable RNA cyclase activity
6116	S000005369	ORF	Verified	YOL009C	MDM12	15	310139	309324	C	Mitochondrial outer membrane protein, required for transmission of mitochondria to daughter cells; exists in a complex with Mmm1p and Mdm10p
6118	S000005368	ORF	Uncharacterized	YOL008W	n.a.	15	310312	310935	W	Hypothetical protein
6120	S000005367	ORF	Uncharacterized	YOL007C	n.a.	15	312367	311342	C	Appears to be a structural component of the chitin synthase 3 complex
6122	S000005366	ORF	Verified	YOL006C	TOP1	15	315387	313078	C	Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination
6124	S000005365	ORF	Verified	YOL005C	RPB11	15	316175	315813	C	RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit
6126	S000005364	ORF	Verified	YOL004W	SIN3	15	316938	321548	W	DNA binding subunit of Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression of meiosis-specific genes during vegetative growth and silencing
6128	S000005363	ORF	Uncharacterized	YOL003C	n.a.	15	322994	321858	C	DHHC-CRD protein
6130	S000005362	ORF	Verified	YOL002C	IZH2	15	324364	323411	C	Membrane protein involved in zinc metabolism, member of the four-protein IZH family, direct target of the Zap1p transcription factor, expression induced by zinc deficiency and fatty acids, deletion increases sensitivity to elevated zinc
6132	S000005361	ORF	Verified	YOL001W	PHO80	15	325249	326130	W	Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p; deletion of PHO80 leads to aminoglycoside supersensitivity; truncated form of PHO80 affects vacuole inheritance
6138	S000005527	ORF	Verified	YOR001W	RRP6	15	326832	329033	W	Exonuclease component of the nuclear exosome; contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus
6140	S000005528	ORF	Verified	YOR002W	ALG6	15	329417	331051	W	Glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease
6142	S000005529	ORF	Verified	YOR003W	YSP3	15	331455	332891	W	Putative precursor to the subtilisin-like protease III
6144	S000005530	ORF	Uncharacterized	YOR004W	n.a.	15	333592	334356	W	Protein required for cell viability
6146	S000005531	ORF	Verified	YOR005C	DNL4	15	337343	334509	C	DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, catalyzes DNA ligation as part of a complex with Lif1p and Nej1p; involved in meiosis, not essential for vegetative growth
6148	S000005532	ORF	Uncharacterized	YOR006C	n.a.	15	338621	337680	C	Hypothetical protein
6150	S000005533	ORF	Verified	YOR007C	SGT2	15	339978	338938	C	Glutamine-rich cytoplasmic protein of unknown function, contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; conserved in human and C. elegans
6152	S000006705	tRNA	n.a.	tR(ACG)O	n.a.	15	340371	340299	C	tRNA-Arg
6155	S000005534	ORF	Verified	YOR008C	SLG1	15	342414	341278	C	Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response
6157	S000006431	ORF	Uncharacterized	YOR008C-A	n.a.	15	343081	342857	C	diepoxybutane and mitomycin C resistance
6159	S000007628	ORF	Dubious	YOR008W-B	n.a.	15	343928	344029	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
6161	S000005535	ORF	Verified	YOR009W	TIR4	15	344334	345797	W	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock
6163	S000005536	ORF	Verified	YOR010C	TIR2	15	346949	346194	C	Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis
6165	S000005537	ORF	Verified	YOR011W	AUS1	15	349678	353862	W	Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth
6167	S000006747	tRNA	n.a.	tT(AGU)O2	n.a.	15	354112	354040	C	tRNA-Thr
6171	S000028581	ORF	Uncharacterized	YOR011W-A	n.a.	15	355651	355857	W	Identified by fungal homology and RT-PCR
6173	S000005538	ORF	Uncharacterized	YOR012W	n.a.	15	356542	356955	W	Hypothetical protein
6175	S000005539	ORF	Dubious	YOR013W	n.a.	15	356750	357220	W	Hypothetical protein
6177	S000005540	ORF	Verified	YOR014W	RTS1	15	357673	359946	W	B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A
6179	S000005541	ORF	Dubious	YOR015W	n.a.	15	359992	360351	W	Hypothetical protein
6181	S000005542	ORF	Verified	YOR016C	ERP4	15	361083	360460	C	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
6183	S000005543	ORF	Verified	YOR017W	PET127	15	361411	363813	W	Protein with a role in mitochondrial RNA stability and/or processing, located in the mitochondrial membrane
6185	S000005544	ORF	Verified	YOR018W	ROD1	15	364368	366881	W	Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase
6187	S000005545	ORF	Uncharacterized	YOR019W	n.a.	15	368126	370318	W	Hypothetical protein
6189	S000005546	ORF	Verified	YOR020C	HSP10	15	370843	370523	C	Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES
6191	S000028526	ORF	Uncharacterized	YOR020W-A	n.a.	15	371684	371956	W	Identified by homology to <i>Ashbya gossypii</i>
6193	S000005547	ORF	Uncharacterized	YOR021C	n.a.	15	373438	372797	C	Hypothetical protein
6195	S000005548	ORF	Uncharacterized	YOR022C	n.a.	15	375856	373709	C	Hypothetical protein
6197	S000005549	ORF	Verified	YOR023C	AHC1	15	377711	376011	C	Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex
6199	S000005550	ORF	Dubious	YOR024W	n.a.	15	377846	378169	W	Hypothetical protein
6201	S000005551	ORF	Verified	YOR025W	HST3	15	378218	379561	W	Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
6203	S000005552	ORF	Verified	YOR026W	BUB3	15	379780	380805	W	Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p
6205	S000005553	ORF	Verified	YOR027W	STI1	15	381052	382821	W	Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein
6207	S000005554	ORF	Verified	YOR028C	CIN5	15	384419	383532	C	Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus
6209	S000005555	ORF	Dubious	YOR029W	n.a.	15	384599	384934	W	Hypothetical protein
6211	S000005556	ORF	Verified	YOR030W	DFG16	15	386824	388683	W	Probable multiple transmembrane protein, involved in invasive growth upon nitrogen starvation; required for accumulation of processed Rim101p
6213	S000005557	ORF	Verified	YOR031W	CRS5	15	389212	389421	W	Copper-binding metallothionein, required for wild-type copper resistance
6215	S000005558	ORF	Verified	YOR032C	HMS1	15	391074	389770	C	C2H2 zinc-finger protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant
6217	S000028710	ORF	Uncharacterized	YOR032W-A	n.a.	15	392175	392375	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6219	S000005559	ORF	Verified	YOR033C	EXO1	15	394523	392415	C	5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains
6221	S000005560	ORF	Verified	YOR034C	AKR2	15	397085	394836	C	Ankyrin repeat-containing protein of unknown function, similar to Akr1p; possibly involved in constitutive endocytosis of Ste3p
6223	S000028856	ORF	Uncharacterized	YOR034C-A	n.a.	15	397667	397425	C	Identified by expression profiling and mass spectrometry
6225	S000005561	ORF	Verified	YOR035C	SHE4	15	400103	397734	C	Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization
6227	S000005562	ORF	Verified	YOR036W	PEP12	15	400347	401213	W	Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin
6229	S000005563	ORF	Verified	YOR037W	CYC2	15	401554	402654	W	Mitochondrial protein required for normal abundance of mitochondrial cytochrome c (Cyc1p) and for mitochondrial osmotic stability; may be involved in regulating the activity of cytochrome c heme lyase (Cyc3p); potential Cdc28p substrate
6231	S000005564	ORF	Verified	YOR038C	HIR2	15	405387	402760	C	Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3, and H4 genes; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p
6233	S000005565	ORF	Verified	YOR039W	CKB2	15	405767	406543	W	protein kinase CK2, beta' subunit
6235	S000005566	ORF	Verified	YOR040W	GLO4	15	407063	407920	W	Mitochondrial glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate
6237	S000007292	snoRNA	n.a.	snR9	SNR9	15	408133	407947	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2339
6239	S000005568	ORF	Uncharacterized	YOR042W	CUE5	15	408424	409659	W	Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
6241	S000005567	ORF	Dubious	YOR041C	n.a.	15	408788	408357	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the uncharacterized gene CUE5; deletion in cyr1 mutant results in loss of stress resistance
6243	S000006453	snoRNA	n.a.	snR62	SNR62	15	409863	409764	C	guides 2'-O-methylation on large subunit rRNA at U1886; small nucleolar RNA snR62
6245	S000005569	ORF	Verified	YOR043W	WHI2	15	410869	412329	W	Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression
6247	S000005570	ORF	Uncharacterized	YOR044W	n.a.	15	413006	413479	W	Hypothetical protein
6249	S000005571	ORF	Verified	YOR045W	TOM6	15	413851	414036	W	involved in supporting the cooperativity between receptors and the general insertion pore and facilitating the release of preproteins from import components; outer mitochondrial membrane protein, component of the mitochondiral protein translocation complex, associates with TOM40
6251	S000005572	ORF	Verified	YOR046C	DBP5	15	415907	414459	C	Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus
6253	S000005573	ORF	Verified	YOR047C	STD1	15	417681	416347	C	Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p
6255	S000005574	ORF	Verified	YOR048C	RAT1	15	421650	418630	C	Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snRNA processing as well as mRNA transcription termination
6257	S000005575	ORF	Verified	YOR049C	RSB1	15	423732	422668	C	Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane
6259	S000005576	ORF	Dubious	YOR050C	n.a.	15	424618	424271	C	Hypothetical protein
6261	S000005577	ORF	Uncharacterized	YOR051C	n.a.	15	426085	424847	C	Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
6263	S000005578	ORF	Uncharacterized	YOR052C	n.a.	15	427225	426773	C	Hypothetical protein
6265	S000005579	ORF	Dubious	YOR053W	n.a.	15	427818	428159	W	Hypothetical protein
6267	S000005581	ORF	Dubious	YOR055W	n.a.	15	429479	429913	W	Hypothetical protein
6269	S000005580	ORF	Verified	YOR054C	VHS3	15	429858	427834	C	Functionally redundant (see also SIS2) inhibitory subunit of Ppz1p, a PP1c-related ser/thr protein phosphatase Z isoform; synthetically lethal with sis2; putative phosphopantothenoylcysteine decarboxylase involved in coenzyme A biosynthesis
6271	S000005582	ORF	Verified	YOR056C	NOB1	15	431627	430248	C	Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA
6273	S000005583	ORF	Verified	YOR057W	SGT1	15	432187	433374	W	Probable cochaperone, regulates activity of Cyr1p (adenylyl cyclase); involved in assembly of the kinetochore complex, associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex
6275	S000005584	ORF	Verified	YOR058C	ASE1	15	436346	433689	C	Member of a family of microtubule-associated proteins (MAPs) that function at the mitotic spindle midzone; required for spindle elongation; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate
6279	S000006634	tRNA	n.a.	tK(UUU)O	n.a.	15	438644	438739	W	tRNA-Lys
6280	S000034218	intron	n.a.	n.a.	n.a.	15	438681	438703	W	n.a.
6283	S000005585	ORF	Uncharacterized	YOR059C	n.a.	15	440259	438907	C	Hypothetical protein
6285	S000005586	ORF	Uncharacterized	YOR060C	n.a.	15	441164	440391	C	Protein required for cell viability
6287	S000005587	ORF	Verified	YOR061W	CKA2	15	441535	442554	W	may have a role in regulation and/or execution of the eukaryotic cell cycle; alpha' subunit of casein kinase II
6289	S000005588	ORF	Uncharacterized	YOR062C	n.a.	15	443532	442726	C	Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1p
6291	S000005589	ORF	Verified	YOR063W	RPL3	15	444687	445850	W	Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus
6293	S000005590	ORF	Verified	YOR064C	YNG1	15	446739	446080	C	Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; has similarity to the human tumor suppressor ING1
6295	S000005591	ORF	Verified	YOR065W	CYT1	15	447440	448369	W	Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex
6297	S000005592	ORF	Uncharacterized	YOR066W	n.a.	15	449437	451326	W	Protein of unknown function; potential Cdc28p substrate
6299	S000005593	ORF	Verified	YOR067C	ALG8	15	453463	451730	C	Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p
6301	S000005595	ORF	Verified	YOR069W	VPS5	15	453769	455796	W	Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p
6303	S000005594	ORF	Verified	YOR068C	VAM10	15	454214	453870	C	Protein involved in vacuole morphogenesis; acts at an early step of homotypic vacuole fusion that is required for vacuole tethering
6305	S000005596	ORF	Verified	YOR070C	GYP1	15	457821	455908	C	Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion
6307	S000005597	ORF	Uncharacterized	YOR071C	n.a.	15	461277	459481	C	Hypothetical protein
6309	S000005598	ORF	Dubious	YOR072W	n.a.	15	461503	461817	W	Hypothetical protein
6311	S000028582	ORF	Dubious	YOR072W-A	n.a.	15	461792	462040	W	Identified by fungal homology and RT-PCR
6313	S000006688	tRNA	n.a.	tP(UGG)O2	SUF11	15	464451	464552	W	tRNA-Pro
6314	S000031047	intron	n.a.	n.a.	n.a.	15	464487	464516	W	n.a.
6317	S000028516	ORF	Uncharacterized	YOR072W-B	n.a.	15	464470	464631	W	Identified by expression profiling and mass spectrometry
6319	S000005599	ORF	Verified	YOR073W	SGO1	15	464772	466544	W	Component of the spindle checkpoint, involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability
6321	S000028583	ORF	Dubious	YOR073W-A	n.a.	15	467391	467624	W	Identified by fungal homology and RT-PCR
6323	S000005600	ORF	Verified	YOR074C	CDC21	15	467590	466676	C	Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S
6326	S000034993	intron	n.a.	n.a.	n.a.	15	467490	467356	C	n.a.
6327	S000005601	ORF	Verified	YOR075W	UFE1	15	468213	469253	W	t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex
6329	S000005602	ORF	Verified	YOR076C	SKI7	15	471621	469378	C	Antiviral adaptor protein that mediates interactions via its N-terminus between the exosome and Ski complex (Ski2p, Ski3p, Ski8p) which operate in the 3'-to-5' mRNA-decay pathway; cytoplasmic protein required for degrading nonstop mRNAs
6331	S000005603	ORF	Verified	YOR077W	RTS2	15	471900	472598	W	Basic zinc-finger protein, similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication
6333	S000005604	ORF	Verified	YOR078W	BUD21	15	472726	473370	W	Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern
6335	S000005605	ORF	Verified	YOR079C	ATX2	15	474417	473476	C	Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation
6337	S000005606	ORF	Verified	YOR080W	DIA2	15	474553	476793	W	Protein of unknown function, involved in invasive and pseudohyphal growth
6339	S000005607	ORF	Uncharacterized	YOR081C	n.a.	15	479189	476940	C	Protein of unknown function, localizes to lipid particles; potential Cdc28p substrate
6341	S000005609	ORF	Verified	YOR083W	WHI5	15	479534	480421	W	Protein that regulates the critical cell size required for passage through Start and commitment to cell division; may act upstream of SCB binding factor (SBF) and MCB binding factor (MBF); periodically expressed in G1
6343	S000005608	ORF	Dubious	YOR082C	n.a.	15	479638	479297	C	Hypothetical protein
6345	S000005610	ORF	Verified	YOR084W	n.a.	15	480588	481751	W	Putative lipase of the peroxisomal matrix; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
6347	S000005611	ORF	Verified	YOR085W	OST3	15	482034	483086	W	Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins
6349	S000005612	ORF	Verified	YOR086C	TCB1	15	486780	483220	C	Contains three calcium and lipid binding domains; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; C-terminal portion of Tcb1p, Tcb2p and Tcb3p interact
6351	S000006676	tRNA	n.a.	tN(GUU)O2	n.a.	15	487440	487513	W	tRNA-Asn
6353	S000005613	ORF	Verified	YOR087W	YVC1	15	487708	489735	W	Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock
6355	S000005615	ORF	Verified	YOR089C	VPS21	15	490829	490197	C	GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog
6357	S000005616	ORF	Verified	YOR090C	PTC5	15	492842	491124	C	Mitochondrially localized type 2C protein phosphatase; contains Mg2+/Mn2+-dependent casein phosphatase activity in vitro but in vivo substrates are unknown
6359	S000005617	ORF	Uncharacterized	YOR091W	n.a.	15	493265	494470	W	Hypothetical protein
6361	S000005618	ORF	Verified	YOR092W	ECM3	15	495127	496968	W	Non-essential protein of unknown function
6363	S000005619	ORF	Uncharacterized	YOR093C	n.a.	15	502452	497506	C	Hypothetical protein
6365	S000005620	ORF	Verified	YOR094W	ARF3	15	502795	503346	W	Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity
6367	S000005621	ORF	Verified	YOR095C	RKI1	15	504328	503552	C	Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway
6369	S000005622	ORF	Verified	YOR096W	RPS7A	15	505794	506767	W	Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins
6372	S000034379	intron	n.a.	n.a.	n.a.	15	505938	506338	W	n.a.
6373	S000005623	ORF	Uncharacterized	YOR097C	n.a.	15	507505	506978	C	Hypothetical protein
6375	S000005624	ORF	Verified	YOR098C	NUP1	15	511178	507948	C	Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate
6377	S000005625	ORF	Verified	YOR099W	KTR1	15	511825	513006	W	Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
6379	S000005626	ORF	Verified	YOR100C	CRC1	15	514278	513295	C	Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation
6381	S000005627	ORF	Verified	YOR101W	RAS1	15	515244	516173	W	GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes
6383	S000005628	ORF	Dubious	YOR102W	n.a.	15	516423	516773	W	Protein required for cell viability
6385	S000005629	ORF	Verified	YOR103C	OST2	15	516841	516449	C	Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins
6387	S000005630	ORF	Verified	YOR104W	PIN2	15	517642	518490	W	Protein that induces appearance of [PIN+] prion when overproduced
6389	S000005631	ORF	Dubious	YOR105W	n.a.	15	518195	518521	W	Hypothetical protein
6391	S000005632	ORF	Verified	YOR106W	VAM3	15	519121	519972	W	Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein trafficking; member of the syntaxin family of proteins
6393	S000005633	ORF	Verified	YOR107W	RGS2	15	521353	522282	W	Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p
6395	S000005634	ORF	Verified	YOR108W	LEU9	15	523027	524841	W	Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant
6397	S000028711	ORF	Dubious	YOR108C-A	n.a.	15	524814	524605	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6399	S000005635	ORF	Verified	YOR109W	INP53	15	525278	528601	W	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in a TGN (trans Golgi network)-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches
6401	S000005636	ORF	Verified	YOR110W	TFC7	15	528941	530248	W	One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes
6403	S000005637	ORF	Uncharacterized	YOR111W	n.a.	15	530429	531127	W	Hypothetical protein
6405	S000005638	ORF	Uncharacterized	YOR112W	n.a.	15	531508	533793	W	Hypothetical protein
6407	S000005639	ORF	Verified	YOR113W	AZF1	15	534075	536819	W	Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance
6409	S000005640	ORF	Uncharacterized	YOR114W	n.a.	15	537570	538454	W	Hypothetical protein
6411	S000005641	ORF	Verified	YOR115C	TRS33	15	539465	538659	C	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic
6413	S000005642	ORF	Verified	YOR116C	RPO31	15	544145	539763	C	RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit
6415	S000005643	ORF	Verified	YOR117W	RPT5	15	545029	546333	W	One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription
6417	S000005644	ORF	Uncharacterized	YOR118W	n.a.	15	546857	548560	W	Hypothetical protein
6419	S000005645	ORF	Verified	YOR119C	RIO1	15	550246	548792	C	Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA
6421	S000005646	ORF	Verified	YOR120W	GCY1	15	551114	552052	W	Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism
6423	S000005647	ORF	Dubious	YOR121C	n.a.	15	552103	551798	C	Hypothetical protein
6425	S000005648	ORF	Verified	YOR122C	PFY1	15	552887	552298	C	Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, plays a role in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol
6428	S000033160	intron	n.a.	n.a.	n.a.	15	552874	552666	C	n.a.
6429	S000005649	ORF	Verified	YOR123C	LEO1	15	554570	553176	C	Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation
6431	S000005650	ORF	Verified	YOR124C	UBP2	15	558642	554824	C	Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terminus of ubiquitin fusions; capable of cleaving polyubiquitin and possesses isopeptidase activity
6433	S000005651	ORF	Verified	YOR125C	CAT5	15	559731	559030	C	Mitochondrial inner membrane protein directly involved in ubiquinone biosynthesis, essential for several other metabolic pathways including respiration and gluconeogenic gene activation
6435	S000005652	ORF	Verified	YOR126C	IAH1	15	560677	559961	C	Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing
6437	S000005653	ORF	Verified	YOR127W	RGA1	15	561170	564193	W	GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth
6439	S000005654	ORF	Verified	YOR128C	ADE2	15	566191	564476	C	Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine
6441	S000005655	ORF	Verified	YOR129C	n.a.	15	569558	566877	C	Putative component of the outer plaque of the spindle pole body; may be involved in cation homeostasis or multidrug resistance
6443	S000005656	ORF	Verified	YOR130C	ORT1	15	570807	569929	C	Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome
6445	S000006545	tRNA	n.a.	tD(GUC)O	n.a.	15	571958	572029	W	tRNA-Asp
6447	S000005657	ORF	Uncharacterized	YOR131C	n.a.	15	572838	572182	C	Hypothetical protein
6449	S000005658	ORF	Verified	YOR132W	VPS17	15	573175	574830	W	Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation
6451	S000005659	ORF	Verified	YOR133W	EFT1	15	575098	577626	W	Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
6453	S000005660	ORF	Verified	YOR134W	BAG7	15	578564	579793	W	Rho GTPase activating protein (RhoGAP), stimulates the intrinsic GTPase activity of Rho1p, which plays a role in actin cytoskeleton organization and control of cell wall synthesis; structurally and functionally related to Sac7p
6455	S000005662	ORF	Verified	YOR136W	IDH2	15	580250	581359	W	Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
6457	S000005661	ORF	Dubious	YOR135C	n.a.	15	580500	580159	C	Hypothetical protein
6459	S000005663	ORF	Verified	YOR137C	SIA1	15	583681	581813	C	Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose
6461	S000005664	ORF	Uncharacterized	YOR138C	n.a.	15	586324	584309	C	Hypothetical protein
6463	S000005666	ORF	Verified	YOR140W	SFL1	15	586981	589281	W	Transcription repressor involved in regulation of flocculation-related genes, inhibits transcription by recruiting general corepressor Cyc8p-Tup1p to different promoters; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p
6465	S000005665	ORF	Dubious	YOR139C	n.a.	15	587342	586950	C	Hypothetical protein
6467	S000005667	ORF	Verified	YOR141C	ARP8	15	592587	589942	C	Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes
6469	S000005668	ORF	Verified	YOR142W	LSC1	15	593057	594046	W	Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate
6471	S000006573	tRNA	n.a.	tG(CCC)O	SUF5	15	594425	594354	C	tRNA-Gly
6484	S000005669	ORF	Verified	YOR143C	THI80	15	602342	601383	C	Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate)
6486	S000005670	ORF	Verified	YOR144C	ELG1	15	605092	602717	C	Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; mutants are sensitive to DNA damage
6488	S000005672	ORF	Dubious	YOR146W	n.a.	15	605873	606178	W	Protein required for cell viability
6490	S000005671	ORF	Verified	YOR145C	PNO1	15	606171	605347	C	Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain
6492	S000005673	ORF	Verified	YOR147W	MDM32	15	606514	608475	W	Mitochondrial inner membrane protein with similarity to Mdm31p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34
6494	S000005674	ORF	Verified	YOR148C	SPP2	15	609197	608640	C	Essential protein that promotes the first step of splicing and is required for the final stages of spliceosome maturation; interacts with Prp2p, which may release Spp2p from the spliceosome following the first cleavage reaction
6496	S000005675	ORF	Verified	YOR149C	SMP3	15	611388	609838	C	Alpha 1,2-mannosyltransferase involved in glycosyl phosphatidyl inositol (GPI) biosynthesis; required for addition of the fourth, side branching mannose to the GPI core structure
6498	S000005676	ORF	Verified	YOR150W	MRPL23	15	611999	612490	W	Mitochondrial ribosomal protein of the large subunit
6500	S000005677	ORF	Verified	YOR151C	RPB2	15	616671	612997	C	RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit
6502	S000005678	ORF	Uncharacterized	YOR152C	n.a.	15	618288	617518	C	Hypothetical protein
6504	S000005679	ORF	Verified	YOR153W	PDR5	15	619840	624375	W	Short-lived membrane ABC (ATP-binding cassette) transporter, actively exports various drugs, expression regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth
6506	S000005680	ORF	Uncharacterized	YOR154W	n.a.	15	624729	626492	W	Hypothetical protein
6508	S000005681	ORF	Verified	YOR155C	ISN1	15	627980	626628	C	Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase, catalyzes the breakdown of IMP to inosine, does not show similarity to known 5'-nucleotidases from other organisms
6510	S000005682	ORF	Verified	YOR156C	NFI1	15	630540	628360	C	SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins
6512	S000005683	ORF	Verified	YOR157C	PUP1	15	631751	630966	C	Endopeptidase with trypsin-like activity that cleaves after basic residues; beta-type subunit of 20S proteasome synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z
6514	S000005684	ORF	Verified	YOR158W	PET123	15	632164	633120	W	Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator
6516	S000005685	ORF	Verified	YOR159C	SME1	15	633566	633282	C	Required for pre-mRNA splicing, cap modification and U1, U2, U4 and U5 snRNA stability; homologue of human E core protein
6518	S000005686	ORF	Verified	YOR160W	MTR10	15	633839	636757	W	Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export
6520	S000028713	ORF	Dubious	YOR161W-A	n.a.	15	637574	637654	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6522	S000028714	ORF	Dubious	YOR161W-B	n.a.	15	637975	638235	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6524	S000005687	ORF	Verified	YOR161C	PNS1	15	638558	636939	C	Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport
6526	S000028712	ORF	Uncharacterized	YOR161C-C	n.a.	15	639267	639121	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6528	S000005688	ORF	Verified	YOR162C	YRR1	15	641992	639560	C	Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes
6530	S000005689	ORF	Verified	YOR163W	DDP1	15	642741	643307	W	Diadenosine polyphosphate hydrolase, member of the MutT family of nucleotide hydrolases with high specificity for diadenosine hexa- and pentaphosphates, required for efficient hydrolysis of diphosphorylated inositol polyphosphates
6532	S000005690	ORF	Uncharacterized	YOR164C	n.a.	15	644332	643394	C	Hypothetical protein
6534	S000005691	ORF	Verified	YOR165W	SEY1	15	644566	646896	W	Protein of unknown function, contains two predicted GTP-binding motifs Gn.a.XGKS and DXXG near the N-terminus, homolog of the Arabidopsis gene RHD3 (Root Hair Defective)
6536	S000005692	ORF	Uncharacterized	YOR166C	n.a.	15	648502	647126	C	Hypothetical protein
6538	S000005693	ORF	Verified	YOR167C	RPS28A	15	649007	648804	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Ap and has similarity to rat S28 ribosomal protein
6540	S000005694	ORF	Verified	YOR168W	GLN4	15	649303	651732	W	Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu); N-terminal domain proposed to be involved in enzyme-tRNA interactions
6542	S000005695	ORF	Dubious	YOR169C	n.a.	15	651840	651376	C	Protein required for cell viability
6544	S000005696	ORF	Dubious	YOR170W	n.a.	15	651858	652163	W	Hypothetical protein
6546	S000005697	ORF	Verified	YOR171C	LCB4	15	653884	652010	C	Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes
6548	S000005698	ORF	Verified	YOR172W	YRM1	15	654210	656570	W	Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes
6550	S000005699	ORF	Verified	YOR173W	DCS2	15	657132	658325	W	Non-essential protein containing a HIT (histidine triad) motif; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, transcript accumulates under glucose limitation, similar to Dcs1p
6552	S000005700	ORF	Verified	YOR174W	MED4	15	658747	659601	W	Member of RNA Polymerase II transcriptional regulation mediator; Stoichiometric member of mediator complex
6554	S000005701	ORF	Uncharacterized	YOR175C	n.a.	15	661674	659815	C	Member of the MBOAT family of putative membrane-bound O-acyltransferases
6556	S000005702	ORF	Verified	YOR176W	HEM15	15	662401	663582	W	Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway; Yfh1p mediates the use of iron by Hem15p
6558	S000006766	tRNA	n.a.	tV(AAC)O	n.a.	15	663885	663812	C	tRNA-Val
6563	S000005703	ORF	Verified	YOR177C	MPC54	15	667179	665785	C	Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate
6565	S000005704	ORF	Verified	YOR178C	GAC1	15	670241	667860	C	Regulatory subunit for Glc7p (protein phosphatase I) for glycogen synthesis; regulatory role also predicted for glucose repression and ion homeostasis; potential Cdc28p substrate
6567	S000005705	ORF	Verified	YOR179C	SYC1	15	672411	671845	C	Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a role in 3' end formation of both polyadenylated and non-polyadenylated RNAs
6569	S000005706	ORF	Verified	YOR180C	DCI1	15	675167	674352	C	Peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, involved in fatty acid metabolism, contains peroxisome targeting signals at amino and carboxy termini
6571	S000005707	ORF	Verified	YOR181W	LAS17	15	675939	677840	W	Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments; localizes with the Arp2/3 complex to actin patches; homolog of the human Wiskott-Aldrich syndrome protein (WASP)
6573	S000005708	ORF	Verified	YOR182C	RPS30B	15	678793	678191	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Ap and has similarity to rat S30 ribosomal protein
6576	S000030005	intron	n.a.	n.a.	n.a.	15	678790	678380	C	n.a.
6577	S000005709	ORF	Uncharacterized	YOR183W	FYV12	15	678872	679261	W	Protein of unknown function, required for survival upon exposure to K1 killer toxin
6579	S000005710	ORF	Verified	YOR184W	SER1	15	679357	680544	W	3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p
6581	S000007300	snoRNA	n.a.	snR36	SNR36	15	680996	680642	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of small subunit rRNA at position 1185
6583	S000005711	ORF	Verified	YOR185C	GSP2	15	682106	681444	C	GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability
6585	S000005712	ORF	Uncharacterized	YOR186W	n.a.	15	683111	683545	W	Hypothetical protein
6587	S000028715	ORF	Dubious	YOR186C-A	n.a.	15	683538	683329	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6589	S000005713	ORF	Verified	YOR187W	TUF1	15	684030	685343	W	Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans
6591	S000005714	ORF	Verified	YOR188W	MSB1	15	685767	689180	W	Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4
6593	S000005715	ORF	Verified	YOR189W	IES4	15	689624	689974	W	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
6595	S000005716	ORF	Verified	YOR190W	SPR1	15	690695	692032	W	Sporulation regulated genes; sporulation-specific exo-1,3-beta-glucanase
6597	S000005717	ORF	Verified	YOR191W	RIS1	15	692475	697334	W	Member of the SWI/SNF family of DNA-dependent ATPases, plays a role in antagonizing silencing during mating-type switching, contains an N-terminal domain that interacts with Sir4p and a C-terminal SNF2 domain
6599	S000005718	ORF	Uncharacterized	YOR192C	n.a.	15	700567	698768	C	Hypothetical protein
6604	S000028857	ORF	Uncharacterized	YOR192C-C	n.a.	15	704224	703988	C	Identified by expression profiling and mass spectrometry
6616	S000006665	tRNA	n.a.	tM(CAU)O1	IMT1	15	710201	710272	W	Initiator methionine tRNA, tRNA(IMet), one of four initiator methionine tRNA genes in yeast that are functional for translation
6618	S000005719	ORF	Verified	YOR193W	PEX27	15	710446	711576	W	Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number, interacts with homologous protein Pex25p
6620	S000005720	ORF	Verified	YOR194C	TOA1	15	712543	711683	C	Transcription factor IIA, large chain
6622	S000005721	ORF	Verified	YOR195W	SLK19	15	712866	715331	W	Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate
6624	S000005722	ORF	Verified	YOR196C	LIP5	15	716837	715593	C	Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase
6626	S000005723	ORF	Verified	YOR197W	MCA1	15	717023	718384	W	Putative cysteine protease similar to mammalian caspases, involved in regulation of apoptosis upon hydrogen peroxide treatment
6628	S000005724	ORF	Verified	YOR198C	BFR1	15	720065	718653	C	Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity
6630	S000005725	ORF	Dubious	YOR199W	n.a.	15	720181	720510	W	Hypothetical protein
6632	S000005726	ORF	Dubious	YOR200W	n.a.	15	720417	720815	W	Hypothetical protein
6634	S000005727	ORF	Verified	YOR201C	n.a.	15	721708	720470	C	Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA
6636	S000005728	ORF	Verified	YOR202W	HIS3	15	721946	722608	W	Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p
6638	S000005729	ORF	Dubious	YOR203W	n.a.	15	722565	722918	W	Protein required for cell viability
6640	S000005730	ORF	Verified	YOR204W	DED1	15	722911	724725	W	ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility
6642	S000005731	ORF	Uncharacterized	YOR205C	n.a.	15	727234	725564	C	The authentic, non-tagged protein was localized to the mitochondria
6644	S000005732	ORF	Verified	YOR206W	NOC2	15	727512	729644	W	Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors
6646	S000005733	ORF	Verified	YOR207C	RET1	15	733457	730008	C	Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs
6648	S000005734	ORF	Verified	YOR208W	PTP2	15	733925	736177	W	Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus
6650	S000005735	ORF	Verified	YOR209C	NPT1	15	737726	736437	C	Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus
6652	S000005736	ORF	Verified	YOR210W	RPB10	15	738320	738532	W	RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III
6654	S000005737	ORF	Verified	YOR211C	MGM1	15	741632	738924	C	Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy
6656	S000005738	ORF	Verified	YOR212W	STE4	15	742910	744181	W	G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats
6658	S000005739	ORF	Verified	YOR213C	SAS5	15	745281	744535	C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which  acetylates free histones and nucleosomes and regulates transcriptional silencing; stimulates Sas2p HAT activity
6660	S000005740	ORF	Uncharacterized	YOR214C	n.a.	15	746303	745593	C	Hypothetical protein
6662	S000005741	ORF	Uncharacterized	YOR215C	n.a.	15	747282	746725	C	Hypothetical protein
6664	S000005742	ORF	Verified	YOR216C	RUD3	15	748979	747525	C	Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1
6666	S000005743	ORF	Verified	YOR217W	RFC1	15	749301	751886	W	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
6668	S000005744	ORF	Dubious	YOR218C	n.a.	15	751895	751476	C	Protein required for cell viability
6670	S000005745	ORF	Verified	YOR219C	STE13	15	755009	752214	C	Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor
6672	S000005746	ORF	Uncharacterized	YOR220W	n.a.	15	755328	756125	W	Hypothetical protein
6674	S000005747	ORF	Verified	YOR221C	MCT1	15	757831	756476	C	Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling
6677	S000034463	intron	n.a.	n.a.	n.a.	15	757737	757537	C	n.a.
6678	S000005748	ORF	Verified	YOR222W	ODC2	15	758330	759253	W	Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism
6680	S000007299	snoRNA	n.a.	snR35	SNR35	15	759729	759190	C	H/ACA small nucleolar RNA (snoRNA); predicted to guide pseudouridylation of small subunit rRNA at position 1189
6682	S000005749	ORF	Uncharacterized	YOR223W	n.a.	15	759782	760660	W	Hypothetical protein
6684	S000005750	ORF	Verified	YOR224C	RPB8	15	761265	760825	C	RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III
6686	S000005751	ORF	Dubious	YOR225W	n.a.	15	761392	761721	W	Hypothetical protein
6688	S000005752	ORF	Verified	YOR226C	ISU2	15	762084	761614	C	Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable
6690	S000005753	ORF	Uncharacterized	YOR227W	n.a.	15	762825	766565	W	Hypothetical protein
6692	S000005754	ORF	Uncharacterized	YOR228C	n.a.	15	767777	766869	C	Hypothetical protein
6694	S000005755	ORF	Verified	YOR229W	WTM2	15	768409	769812	W	Transcriptional repressor involved in regulation of meiosis and silencing; contains WD repeats
6696	S000005756	ORF	Verified	YOR230W	WTM1	15	770800	772113	W	Transcriptional repressor involved in regulation of meiosis and silencing; contains WD repeats
6698	S000005757	ORF	Verified	YOR231W	MKK1	15	772601	774127	W	Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p
6700	S000028716	ORF	Dubious	YOR231C-A	n.a.	15	773363	773163	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6702	S000005758	ORF	Verified	YOR232W	MGE1	15	774573	775259	W	Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE
6704	S000005759	ORF	Verified	YOR233W	KIN4	15	775846	778248	W	Nonessential protein kinase with unknown cellular role
6706	S000005760	ORF	Verified	YOR234C	RPL33B	15	779405	778555	C	Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable
6709	S000030772	intron	n.a.	n.a.	n.a.	15	779386	778860	C	n.a.
6710	S000005761	ORF	Dubious	YOR235W	n.a.	15	779870	780184	W	Hypothetical protein
6712	S000007294	snoRNA	n.a.	snR17a	SNR17A	15	780107	780596	W	encodes snoRNA U3, SNR17B also encodes snoRNA U3; part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); encodes snoRNA U3, SNR17B also encodes snoRNA U3
6713	S000030175	intron	n.a.	n.a.	n.a.	15	780121	780277	W	n.a.
6716	S000005762	ORF	Verified	YOR236W	DFR1	15	780906	781541	W	Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function
6718	S000005763	ORF	Verified	YOR237W	HES1	15	781994	783298	W	Protein implicated in the regulation of ergosterol biosynthesis; one of a seven member gene family with a common essential function and non-essential unique functions; similar to human oxysterol binding protein (OSBP)
6720	S000005764	ORF	Uncharacterized	YOR238W	n.a.	15	783677	784588	W	Hypothetical protein
6722	S000005765	ORF	Verified	YOR239W	ABP140	15	784857	786744	W	Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases
6726	S000005767	ORF	Verified	YOR241W	MET7	15	786995	788641	W	Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA, present in both the cytoplasm and mitochondria
6728	S000005768	ORF	Verified	YOR242C	SSP2	15	789857	788742	C	Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; SSP2 expression is induced midway in meiosis
6730	S000005769	ORF	Verified	YOR243C	PUS7	15	792241	790211	C	Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); Asp(256) mutation abolishes activity; conserved in archaea, some bacteria, and vertebrates
6732	S000005770	ORF	Verified	YOR244W	ESA1	15	792531	793868	W	Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression
6734	S000005771	ORF	Verified	YOR245C	DGA1	15	795332	794076	C	Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles
6736	S000005772	ORF	Uncharacterized	YOR246C	n.a.	15	796793	795801	C	Protein with similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
6738	S000005773	ORF	Verified	YOR247W	SRL1	15	797676	798308	W	Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants
6740	S000005774	ORF	Dubious	YOR248W	n.a.	15	798013	798315	W	Hypothetical protein
6742	S000005775	ORF	Verified	YOR249C	APC5	15	800731	798674	C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
6744	S000005776	ORF	Verified	YOR250C	CLP1	15	802307	800970	C	Subunit of cleavage factor I (CFI), involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3? end maturation
6746	S000005777	ORF	Uncharacterized	YOR251C	n.a.	15	803464	802550	C	catalyzes transfer of the sulfane atom of thiosulfate to cyanide to form sulfite and thiocyanate
6748	S000005778	ORF	Uncharacterized	YOR252W	n.a.	15	803777	804202	W	Hypothetical protein
6750	S000005779	ORF	Verified	YOR253W	NAT5	15	804376	804906	W	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
6752	S000005780	ORF	Verified	YOR254C	SEC63	15	807022	805031	C	Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
6754	S000005781	ORF	Verified	YOR255W	OSW1	15	807270	808106	W	Protein of unknown function required for the construction of the outer spore wall layers
6756	S000005782	ORF	Uncharacterized	YOR256C	n.a.	15	810681	808252	C	Protein of unknown function with similarity to TRE1/YPL176C; required for cell viability
6758	S000005783	ORF	Verified	YOR257W	CDC31	15	811006	811491	W	Component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; interacts with Kar1p
6760	S000005784	ORF	Verified	YOR258W	HNT3	15	811669	812322	W	Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia
6762	S000005785	ORF	Verified	YOR259C	RPT4	15	813706	812393	C	One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle
6764	S000005786	ORF	Verified	YOR260W	GCD1	15	813982	815718	W	Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression
6766	S000005787	ORF	Verified	YOR261C	RPN8	15	816929	815913	C	Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p
6768	S000005788	ORF	Uncharacterized	YOR262W	n.a.	15	817289	818332	W	Protein required for cell viability
6770	S000005790	ORF	Verified	YOR264W	DSE3	15	818863	820155	W	Daughter cell-specific protein, may help establish daughter fate
6772	S000005789	ORF	Dubious	YOR263C	n.a.	15	819161	818754	C	Hypothetical protein
6774	S000005791	ORF	Verified	YOR265W	RBL2	15	820451	820771	W	Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin
6776	S000005792	ORF	Verified	YOR266W	PNT1	15	821020	822291	W	Mitochondrial inner membrane protein involved in export of proteins from the mitochondrial matrix; overexpression of PNT1 confers resistance to the anti-Pneumocystis carinii drug pentamidine, and deletion confers increased sensitivity
6778	S000005793	ORF	Verified	YOR267C	HRK1	15	824864	822585	C	Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis
6780	S000005794	ORF	Uncharacterized	YOR268C	n.a.	15	825929	825531	C	Hypothetical protein
6782	S000005795	ORF	Verified	YOR269W	PAC1	15	826382	827866	W	Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1
6784	S000005796	ORF	Verified	YOR270C	VPH1	15	830571	828049	C	Subunit of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes
6786	S000005797	ORF	Uncharacterized	YOR271C	n.a.	15	832039	831056	C	Hypothetical protein
6788	S000006497	snoRNA	n.a.	snR8	SNR8	15	832329	832518	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at positions 985 and 959
6790	S000005798	ORF	Verified	YOR272W	YTM1	15	832810	834192	W	Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit
6792	S000005799	ORF	Verified	YOR273C	TPO4	15	836428	834449	C	Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily
6794	S000005800	ORF	Verified	YOR274W	MOD5	15	837671	838957	W	Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms
6796	S000005801	ORF	Verified	YOR275C	RIM20	15	841066	839081	C	Protein involved in proteolytic activation of Rim101p in response to alkaline pH; member of the PalA/AIP1/Alix family; interacts with the ESCRT-III subunits Snf7p, suggesting a relationship between the response to pH and multivesicular body formation
6798	S000005802	ORF	Verified	YOR276W	CAF20	15	841330	841815	W	Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E
6800	S000005803	ORF	Dubious	YOR277C	n.a.	15	841820	841512	C	Hypothetical protein
6802	S000007296	snoRNA	n.a.	snR31	SNR31	15	842179	841955	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of small subunit rRNA at position 1000
6804	S000007291	snoRNA	n.a.	snR5	SNR5	15	842400	842603	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at positions 1003 and 1123
6806	S000005804	ORF	Verified	YOR278W	HEM4	15	842814	843641	W	Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in the heme biosynthetic pathway
6808	S000005805	ORF	Verified	YOR279C	RFM1	15	844627	843695	C	DNA-binding protein required for repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p
6810	S000005806	ORF	Verified	YOR280C	FSH3	15	845789	844989	C	Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh1p and Fsh3p
6812	S000005808	ORF	Dubious	YOR282W	n.a.	15	846997	847317	W	Protein required for cell viability
6814	S000005807	ORF	Verified	YOR281C	PLP2	15	847126	846266	C	Essential protein with similarity to phosducins, which are GTPase inhibitors; lethality of null mutation is functionally complemented by expression of mouse phosducin-like protein MgcPhLP
6816	S000005809	ORF	Uncharacterized	YOR283W	n.a.	15	847450	848142	W	Hypothetical protein
6818	S000005810	ORF	Uncharacterized	YOR284W	HUA2	15	848475	849206	W	Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly
6820	S000005811	ORF	Uncharacterized	YOR285W	n.a.	15	849632	850051	W	Hypothetical protein
6822	S000005812	ORF	Uncharacterized	YOR286W	n.a.	15	850277	850726	W	The authentic, non-tagged protein was localized to the mitochondria
6824	S000005813	ORF	Uncharacterized	YOR287C	n.a.	15	851836	850934	C	Protein required for cell viability
6826	S000005814	ORF	Verified	YOR288C	MPD1	15	853074	852118	C	Member of the protein disulfide isomerase (PDI) family; overexpression suppresses the defect in maturation of carboxypeptidase Y, and defects in other essential Pdi1p functions, caused by PDI1 deletion
6828	S000005815	ORF	Uncharacterized	YOR289W	n.a.	15	853354	854109	W	Hypothetical protein
6830	S000006525	tRNA	n.a.	tA(UGC)O	n.a.	15	854256	854184	C	tRNA-Ala
6833	S000005816	ORF	Verified	YOR290C	SNF2	15	860255	855144	C	Catalytic subunit of the 11-subunit SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p
6835	S000005817	ORF	Uncharacterized	YOR291W	n.a.	15	861172	865590	W	Hypothetical protein
6837	S000005818	ORF	Uncharacterized	YOR292C	n.a.	15	866579	865650	C	Hypothetical protein
6839	S000005819	ORF	Verified	YOR293W	RPS10A	15	867095	867849	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10
6842	S000037301	intron	n.a.	n.a.	n.a.	15	867147	867583	W	n.a.
6843	S000028858	ORF	Uncharacterized	YOR293C-A	n.a.	15	868144	867995	C	Identified by expression profiling and mass spectrometry
6845	S000005820	ORF	Verified	YOR294W	RRS1	15	868337	868948	W	Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; mouse homolog shows altered expression in Huntington's disease model mice
6847	S000005821	ORF	Verified	YOR295W	UAF30	15	869205	869891	W	Subunit of UAF (upstream activation factor), which is an RNA polymerase I specific transcription stimulatory factor composed of Uaf30p, Rrn5p, Rrn9p, Rrn10p, histones H3 and H4; deletion decreases cellular growth rate
6849	S000005822	ORF	Uncharacterized	YOR296W	n.a.	15	870199	874068	W	Hypothetical protein
6851	S000005823	ORF	Verified	YOR297C	TIM18	15	875318	874740	C	mitochondrial inner membrane translocase
6853	S000005824	ORF	Verified	YOR298W	MUM3	15	875596	877035	W	Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acetyltransferases
6855	S000007253	ORF	Verified	YOR298C-A	MBF1	15	877682	877227	C	Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations
6857	S000005825	ORF	Verified	YOR299W	BUD7	15	878431	880671	W	Protein involved in bud-site selection; diploid mutants display an axial-like budding pattern
6859	S000005826	ORF	Dubious	YOR300W	HUF1	15	880571	880879	W	Dubious open reading frame, unlikely to encode a protein; HUF1 ORF overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection.
6861	S000005827	ORF	Verified	YOR301W	RAX1	15	880961	882268	W	Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily
6863	S000005828	ORF	Verified	YOR302W	n.a.	15	882761	882838	W	CPA1 uORF , Arginine attenuator peptide, regulates translation of the CPA1 mRNA
6865	S000005829	ORF	Verified	YOR303W	CPA1	15	882895	884130	W	Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader
6867	S000005831	ORF	Verified	YOR304W	ISW2	15	884510	887872	W	Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth
6869	S000005830	ORF	Uncharacterized	YOR304C-A	n.a.	15	888746	888516	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck
6871	S000005832	ORF	Uncharacterized	YOR305W	n.a.	15	889018	889746	W	Hypothetical protein
6873	S000005833	ORF	Verified	YOR306C	MCH5	15	891428	889863	C	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
6875	S000005834	ORF	Verified	YOR307C	SLY41	15	894087	892726	C	Protein involved in ER-to-Golgi transport
6877	S000005835	ORF	Verified	YOR308C	SNU66	15	896382	894619	C	66kD U4/U6.U5 snRNP associated protein
6879	S000005836	ORF	Dubious	YOR309C	n.a.	15	897073	896693	C	Hypothetical protein
6881	S000005837	ORF	Verified	YOR310C	NOP58	15	898355	896820	C	Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA
6883	S000005838	ORF	Verified	YOR311C	HSD1	15	899923	899051	C	Endoplasmic reticulum (ER)-resident membrane protein, overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation
6885	S000005839	ORF	Verified	YOR312C	RPL20B	15	901176	900245	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein
6888	S000032859	intron	n.a.	n.a.	n.a.	15	901169	900763	C	n.a.
6889	S000005840	ORF	Verified	YOR313C	SPS4	15	902869	901853	C	Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage
6891	S000005841	ORF	Dubious	YOR314W	n.a.	15	903038	903367	W	Hypothetical protein
6893	S000007629	ORF	Dubious	YOR314W-A	n.a.	15	904453	904563	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
6895	S000005842	ORF	Uncharacterized	YOR315W	n.a.	15	904755	905795	W	Protein of unknown function, found in the cytoplasm and the nucleus; potential Cdc28p substrate
6897	S000005843	ORF	Verified	YOR316C	COT1	15	907550	906231	C	Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium
6899	S000028584	ORF	Uncharacterized	YOR316C-A	n.a.	15	907930	907721	C	Identified by fungal homology and RT-PCR
6901	S000005844	ORF	Verified	YOR317W	FAA1	15	909338	911440	W	Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; not required for growth on nonfermentable carbon sources; essential for stationary phase
6903	S000005845	ORF	Dubious	YOR318C	n.a.	15	912431	911779	C	Hypothetical protein
6906	S000034045	intron	n.a.	n.a.	n.a.	15	912427	912081	C	n.a.
6907	S000005846	ORF	Verified	YOR319W	HSH49	15	912817	913458	W	U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)
6909	S000005847	ORF	Verified	YOR320C	GNT1	15	915089	913614	C	N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus
6911	S000005848	ORF	Verified	YOR321W	PMT3	15	916025	918286	W	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; target for new antifungals
6913	S000005849	ORF	Uncharacterized	YOR322C	n.a.	15	921057	918601	C	Hypothetical protein
6915	S000005850	ORF	Verified	YOR323C	PRO2	15	922900	921530	C	Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis
6917	S000005852	ORF	Dubious	YOR325W	n.a.	15	924572	925045	W	Hypothetical protein
6919	S000005851	ORF	Verified	YOR324C	FRT1	15	925035	923227	C	Tail-anchored endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress
6921	S000005853	ORF	Verified	YOR326W	MYO2	15	925716	930440	W	One of two type V myosins, involved in polarized distribution of mitochondria; required for mitochondrion and vacuole inheritance and nuclear spindle orientation; moves multiple cargo
6923	S000005854	ORF	Verified	YOR327C	SNC2	15	931076	930729	C	Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins
6925	S000005855	ORF	Verified	YOR328W	PDR10	15	931798	936492	W	ABC (ATP-binding cassette) membrane pump involved in the pleiotropic drug resistance network, regulated by Pdr1p and Pdr3p, similar to Pdr5p
6927	S000028585	ORF	Dubious	YOR329W-A	n.a.	15	939343	939552	W	Identified by fungal homology and RT-PCR
6929	S000005856	ORF	Verified	YOR329C	SCD5	15	939344	936726	C	Protein required for normal cortical actin organization and endocytosis; multicopy suppressor of clathrin deficiency; acts as a targeting subunit for protein phosphatase type 1
6931	S000005857	ORF	Verified	YOR330C	MIP1	15	943458	939616	C	Catalytic subunit of the mitochondrial DNA polymerase
6933	S000005859	ORF	Verified	YOR332W	VMA4	15	943651	944352	W	Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
6935	S000005858	ORF	Dubious	YOR331C	n.a.	15	944117	943560	C	Hypothetical protein
6937	S000005861	ORF	Verified	YOR334W	MRS2	15	944591	946003	W	Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns
6939	S000005860	ORF	Dubious	YOR333C	n.a.	15	944952	944536	C	Spore Wall Formation
6941	S000028717	ORF	Dubious	YOR335W-A	n.a.	15	946563	946643	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
6943	S000005862	ORF	Verified	YOR335C	ALA1	15	949104	946228	C	Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog
6945	S000005863	ORF	Verified	YOR336W	KRE5	15	949768	953865	W	Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects
6947	S000005864	ORF	Verified	YOR337W	TEA1	15	954339	956618	W	Mutants are defective in Ty1 Enhancer-mediated Activation; Ty1 enhancer activator
6949	S000005865	ORF	Uncharacterized	YOR338W	n.a.	15	956893	957984	W	Hypothetical protein
6951	S000005866	ORF	Verified	YOR339C	UBC11	15	958827	958357	C	Ubiquitin-conjugating enzyme most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2
6953	S000005867	ORF	Verified	YOR340C	RPA43	15	960177	959197	C	RNA polymerase I subunit A43
6955	S000005868	ORF	Verified	YOR341W	RPA190	15	960982	965976	W	RNA polymerase I subunit; largest subunit of RNA polymerase I
6957	S000005869	ORF	Uncharacterized	YOR342C	n.a.	15	967620	966661	C	Hypothetical protein
6959	S000005870	ORF	Dubious	YOR343C	n.a.	15	968469	968143	C	Hypothetical protein
6972	S000006666	tRNA	n.a.	tM(CAU)O2	EMT2	15	976416	976488	W	tRNA that accepts methionine; functions in translational elongation but not translational initiation
6974	S000005871	ORF	Verified	YOR344C	TYE7	15	978064	977189	C	Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression
6977	S000006689	tRNA	n.a.	tP(UGG)O3	n.a.	15	980678	980782	W	tRNA-Pro
6978	S000031061	intron	n.a.	n.a.	n.a.	15	980714	980746	W	n.a.
6981	S000005873	ORF	Verified	YOR346W	REV1	15	981823	984780	W	Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA
6983	S000005872	ORF	Dubious	YOR345C	n.a.	15	982157	981807	C	Hypothetical protein
6985	S000005874	ORF	Verified	YOR347C	PYK2	15	986457	984937	C	Pyruvate kinase, one of two isoforms that catalyze the final step in glycolysis; activity appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux
6987	S000005875	ORF	Verified	YOR348C	PUT4	15	988777	986894	C	Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells
6989	S000005876	ORF	Verified	YOR349W	CIN1	15	989784	992828	W	Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
6991	S000005877	ORF	Verified	YOR350C	MNE1	15	994850	992859	C	Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase
6993	S000005878	ORF	Verified	YOR351C	MEK1	15	996506	995013	C	Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, phosphorylates Red1p, interacts with Hop1p; required for meiotic recombination and normal spore viability
6995	S000005879	ORF	Uncharacterized	YOR352W	n.a.	15	997208	998239	W	Hypothetical protein
6997	S000005880	ORF	Verified	YOR353C	SOG2	15	1000823	998448	C	Protein required for cell morphogenesis and cell separation after mitosis
6999	S000005881	ORF	Verified	YOR354C	MSC6	15	1003220	1001142	C	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to mitochondria; msc6 mutants are defective in directing meiotic recombination events to homologous chromatids
7001	S000005882	ORF	Verified	YOR355W	GDS1	15	1005133	1006701	W	Protein of unknown function, required for growth on glycerol as a carbon source
7003	S000005883	ORF	Uncharacterized	YOR356W	n.a.	15	1007217	1009112	W	Hypothetical protein
7005	S000005884	ORF	Verified	YOR357C	GRD19	15	1009708	1009220	C	Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p
7007	S000005885	ORF	Verified	YOR358W	HAP5	15	1010157	1010885	W	Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex
7009	S000005886	ORF	Verified	YOR359W	VTS1	15	1011185	1012756	W	Protein of unknown function, shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic
7011	S000005887	ORF	Verified	YOR360C	PDE2	15	1014817	1013237	C	High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon
7013	S000005888	ORF	Verified	YOR361C	PRT1	15	1017648	1015357	C	Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
7015	S000005889	ORF	Verified	YOR362C	PRE10	15	1018742	1017876	C	20S proteasome alpha-type subunit
7017	S000005890	ORF	Verified	YOR363C	PIP2	15	1023208	1020218	C	Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes
7019	S000005891	ORF	Dubious	YOR364W	n.a.	15	1023367	1023735	W	Hypothetical protein
7021	S000005893	ORF	Dubious	YOR366W	n.a.	15	1025252	1025605	W	Hypothetical protein
7023	S000005892	ORF	Uncharacterized	YOR365C	n.a.	15	1025568	1023457	C	Hypothetical protein
7025	S000005894	ORF	Verified	YOR367W	SCP1	15	1026003	1026605	W	Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin
7027	S000005895	ORF	Verified	YOR368W	RAD17	15	1026839	1028044	W	Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins
7029	S000005896	ORF	Verified	YOR369C	RPS12	15	1028621	1028190	C	Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12
7031	S000005897	ORF	Verified	YOR370C	MRS6	15	1030990	1029179	C	Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
7033	S000005898	ORF	Verified	YOR371C	GPB1	15	1034178	1031485	C	Proposed beta subunit of the heterotrimeric G protein that interacts with the receptor Grp1p, has signaling role in response to nutrients; involved in regulation of pseudohyphal growth through cAMP levels; homolog of Gpb2p
7035	S000005899	ORF	Verified	YOR372C	NDD1	15	1036467	1034803	C	Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes
7037	S000005900	ORF	Verified	YOR373W	NUD1	15	1036830	1039385	W	Component of the spindle pole body outer plaque, required for exit from mitosis
7039	S000005901	ORF	Verified	YOR374W	ALD4	15	1039836	1041395	W	Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed
7041	S000005902	ORF	Verified	YOR375C	GDH1	15	1043038	1041674	C	NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources
7043	S000005903	ORF	Dubious	YOR376W	n.a.	15	1043187	1043555	W	Hypothetical protein
7045	S000028586	ORF	Uncharacterized	YOR376W-A	n.a.	15	1045192	1045347	W	Identified by fungal homology and RT-PCR
7047	S000005904	ORF	Verified	YOR377W	ATF1	15	1046222	1047799	W	Alcohol acetyltransferase with potential roles in lipid and sterol metabolism; responsible for the major part of volatile acetate ester production during fermentation
7049	S000005905	ORF	Uncharacterized	YOR378W	n.a.	15	1049507	1051054	W	Hypothetical protein
7051	S000005906	ORF	Dubious	YOR379C	n.a.	15	1051060	1050722	C	Hypothetical protein
7053	S000005907	ORF	Verified	YOR380W	RDR1	15	1051286	1052926	W	Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins
7055	S000005908	ORF	Verified	YOR381W	FRE3	15	1055541	1057676	W	Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels
7057	S000028587	ORF	Uncharacterized	YOR381W-A	n.a.	15	1058419	1058586	W	Identified by fungal homology and RT-PCR
7059	S000005909	ORF	Verified	YOR382W	FIT2	15	1059527	1059988	W	Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
7061	S000005910	ORF	Verified	YOR383C	FIT3	15	1061051	1060437	C	Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
7063	S000005911	ORF	Verified	YOR384W	FRE5	15	1061560	1063644	W	Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels
7065	S000005912	ORF	Uncharacterized	YOR385W	n.a.	15	1065039	1065911	W	Hypothetical protein
7067	S000005913	ORF	Verified	YOR386W	PHR1	15	1066835	1068532	W	DNA photolyase involved in photoreactivation, repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p
7069	S000005914	ORF	Uncharacterized	YOR387C	n.a.	15	1070237	1069617	C	Hypothetical protein
7071	S000005915	ORF	Verified	YOR388C	FDH1	15	1072919	1071789	C	NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate
7073	S000005916	ORF	Uncharacterized	YOR389W	n.a.	15	1074209	1076083	W	Hypothetical protein
7075	S000005917	ORF	Uncharacterized	YOR390W	n.a.	15	1076780	1077907	W	Hypothetical protein
7077	S000005918	ORF	Uncharacterized	YOR391C	HSP33	15	1079254	1078541	C	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp32p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease
7079	S000005919	ORF	Dubious	YOR392W	n.a.	15	1079278	1079721	W	Hypothetical protein
7081	S000005920	ORF	Verified	YOR393W	ERR1	15	1080272	1081585	W	Protein of unknown function, has similarity to enolases
7083	S000005921	ORF	Uncharacterized	YOR394W	n.a.	15	1082714	1083208	W	Hypothetical protein
7090	S000028718	ORF	Uncharacterized	YOR394C-A	n.a.	15	1084365	1084198	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7095	S000007526	ORF	Uncharacterized	YOR396W	n.a.	15	1087185	1090859	W	Hypothetical protein
7097	S000028719	ORF	Dubious	YOR396C-A	n.a.	15	1090493	1090011	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7101	S000028724	ORF	Dubious	YPL283W-B	n.a.	16	643	1125	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7103	S000028723	ORF	Dubious	YPL283W-A	n.a.	16	1426	2001	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7105	S000006204	ORF	Verified	YPL283C	YRF1-7	16	6007	280	C	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
7108	S000036890	intron	n.a.	n.a.	n.a.	16	5988	5841	C	n.a.
7116	S000006203	ORF	Uncharacterized	YPL282C	n.a.	16	8427	7933	C	Hypothetical protein
7118	S000006202	ORF	Verified	YPL281C	ERR2	16	10870	9557	C	Protein of unknown function, has similarity to enolases
7120	S000006201	ORF	Uncharacterized	YPL280W	HSP32	16	11887	12600	W	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease
7122	S000006200	ORF	Uncharacterized	YPL279C	n.a.	16	14355	13228	C	Hypothetical protein
7124	S000006199	ORF	Uncharacterized	YPL278C	n.a.	16	15355	15053	C	Hypothetical protein
7126	S000006198	ORF	Uncharacterized	YPL277C	n.a.	16	16868	15405	C	Hypothetical protein
7132	S000006195	ORF	Verified	YPL274W	SAM3	16	22938	24701	W	High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p
7134	S000006194	ORF	Verified	YPL273W	SAM4	16	25087	26064	W	S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio
7136	S000006193	ORF	Uncharacterized	YPL272C	n.a.	16	28164	26611	C	Hypothetical protein
7138	S000006192	ORF	Verified	YPL271W	ATP15	16	30079	30267	W	Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
7140	S000006191	ORF	Verified	YPL270W	MDL2	16	30482	32803	W	Half-type ATP-binding cassette (ABC) transporter of the inner mitochondrial membrane
7142	S000006190	ORF	Verified	YPL269W	KAR9	16	33013	34947	W	Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase
7144	S000006189	ORF	Verified	YPL268W	PLC1	16	35236	37845	W	Phosphoinositide-specific phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in kinetochore function and pseudohyphal differentiation
7146	S000006188	ORF	Uncharacterized	YPL267W	n.a.	16	38169	38798	W	Protein of unknown function, potential Cdc28p substrate
7148	S000006187	ORF	Verified	YPL266W	DIM1	16	39121	40077	W	Essential 18S rRNA dimethylase, responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18 S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing
7150	S000006186	ORF	Verified	YPL265W	DIP5	16	41043	42869	W	Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly
7152	S000006185	ORF	Uncharacterized	YPL264C	n.a.	16	44344	43283	C	Hypothetical protein
7154	S000006184	ORF	Verified	YPL263C	KEL3	16	46506	44551	C	Cytoplasmic protein of unknown function
7156	S000006183	ORF	Verified	YPL262W	FUM1	16	47336	48802	W	Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation
7158	S000006181	ORF	Uncharacterized	YPL260W	n.a.	16	49303	50958	W	Hypothetical protein
7160	S000006182	ORF	Dubious	YPL261C	n.a.	16	49304	48996	C	Hypothetical protein
7162	S000006180	ORF	Verified	YPL259C	APM1	16	52671	51244	C	Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting
7164	S000006179	ORF	Verified	YPL258C	THI21	16	55153	53498	C	Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p
7167	S000006776	tRNA	n.a.	tW(CCA)P	n.a.	16	56274	56169	C	tRNA-Trp
7168	S000034120	intron	n.a.	n.a.	n.a.	16	56238	56205	C	n.a.
7184	S000006178	ORF	Uncharacterized	YPL257W	n.a.	16	63279	63860	W	Hypothetical protein
7186	S000006177	ORF	Verified	YPL256C	CLN2	16	66614	64977	C	G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)
7188	S000006176	ORF	Verified	YPL255W	BBP1	16	67725	68882	W	Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p
7190	S000006175	ORF	Verified	YPL254W	HFI1	16	69485	70951	W	Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions
7192	S000006174	ORF	Verified	YPL253C	VIK1	16	73006	71063	C	Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p
7194	S000006172	ORF	Dubious	YPL251W	n.a.	16	73625	73927	W	Protein required for cell viability
7196	S000006173	ORF	Verified	YPL252C	YAH1	16	73881	73363	C	Ferredoxin of the mitochondrial matrix required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; homologous to human adrenodoxin
7198	S000006171	ORF	Uncharacterized	YPL250C	ICY2	16	74719	74309	C	Protein that interacts with the cytoskeleton and is involved in chromatin organization and nuclear transport, interacts genetically with TCP1 and ICY1; potential Cdc28p substrate
7200	S000028589	ORF	Dubious	YPL250W-A	n.a.	16	75702	75989	W	Identified by fungal homology and RT-PCR
7202	S000006438	ORF	Verified	YPL249C-A	RPL36B	16	76239	75699	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA
7205	S000032351	intron	n.a.	n.a.	n.a.	16	76223	75986	C	n.a.
7206	S000006170	ORF	Verified	YPL249C	GYP5	16	79353	76669	C	GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p
7208	S000006169	ORF	Verified	YPL248C	GAL4	16	82356	79711	C	DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p
7210	S000006168	ORF	Uncharacterized	YPL247C	n.a.	16	84196	82625	C	Hypothetical protein
7212	S000006167	ORF	Verified	YPL246C	RBD2	16	85297	84509	C	Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p
7214	S000006166	ORF	Uncharacterized	YPL245W	n.a.	16	85586	86950	W	Hypothetical protein
7216	S000006165	ORF	Verified	YPL244C	HUT1	16	88033	87014	C	Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1
7218	S000006164	ORF	Verified	YPL243W	SRP68	16	88517	90316	W	Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane
7220	S000006163	ORF	Verified	YPL242C	IQG1	16	95109	90622	C	Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family
7222	S000006162	ORF	Verified	YPL241C	CIN2	16	96258	95372	C	Tubulin folding factor C (putative) involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl
7225	S000037282	intron	n.a.	n.a.	n.a.	16	96233	96154	C	n.a.
7226	S000006161	ORF	Verified	YPL240C	HSP82	16	98625	96496	C	Cytoplasmic chaperone (Hsp90 family) required for pheromone signaling and negative regulation of Hsf1p; docks with the mitochondrial import receptor Tom70p for preprotein delivery; interacts with co-chaperones Cns1p, Cpr6p, Cpr7p, and Sti1p
7228	S000006160	ORF	Verified	YPL239W	YAR1	16	99484	100086	W	Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock
7230	S000006158	ORF	Verified	YPL237W	SUI3	16	100496	101353	W	Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding
7232	S000006159	ORF	Dubious	YPL238C	n.a.	16	100863	100474	C	Protein required for cell viability
7234	S000006157	ORF	Uncharacterized	YPL236C	n.a.	16	102702	101608	C	Hypothetical protein
7236	S000006156	ORF	Verified	YPL235W	RVB2	16	103232	104647	W	Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family
7238	S000006155	ORF	Verified	YPL234C	TFP3	16	105440	104946	C	Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen
7240	S000006154	ORF	Verified	YPL233W	NSL1	16	106172	106822	W	Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation
7242	S000006153	ORF	Verified	YPL232W	SSO1	16	107275	108147	W	Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; forms a complex, with t-SNARE Sec9p, that binds v-SNARE Snc2p; also required for sporulation; syntaxin homolog that is functionally redundant with Sso2p
7244	S000006152	ORF	Verified	YPL231W	FAS2	16	108652	114315	W	Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities
7246	S000006151	ORF	Uncharacterized	YPL230W	n.a.	16	115312	116487	W	Up in StarVation
7248	S000006150	ORF	Uncharacterized	YPL229W	n.a.	16	117067	117687	W	Hypothetical protein
7250	S000006149	ORF	Verified	YPL228W	CET1	16	118382	120031	W	Interacts with Ceg1p, the mRNA capping enzyme alpha subunit; removes gamma-phosphate from triphosphate-terminated RNA; mRNA capping enzyme beta subunit (80 kDa), RNA 5'-triphosphatase
7252	S000006148	ORF	Verified	YPL227C	ALG5	16	121167	120163	C	UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum
7254	S000006147	ORF	Verified	YPL226W	NEW1	16	121767	125357	W	ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation, susceptibility to [PSI+] prion induction and aggregation of a fragment of the human Machado-Joseph Disease protein
7256	S000006146	ORF	Uncharacterized	YPL225W	n.a.	16	126006	126446	W	Hypothetical protein
7258	S000006145	ORF	Verified	YPL224C	MMT2	16	128087	126738	C	Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p
7260	S000006144	ORF	Verified	YPL223C	GRE1	16	129137	128631	C	Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway
7262	S000006143	ORF	Uncharacterized	YPL222W	n.a.	16	130161	132227	W	The authentic, non-tagged protein was localized to the mitochondria.
7264	S000028722	ORF	Dubious	YPL222C-A	n.a.	16	132114	131869	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7266	S000006142	ORF	Uncharacterized	YPL221W	n.a.	16	133042	135423	W	Protein of unknown function, overproduction suppresses a pam1 slv3 double null mutation
7268	S000006141	ORF	Verified	YPL220W	RPL1A	16	135789	136442	W	N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal
7270	S000006140	ORF	Verified	YPL219W	PCL8	16	136749	138227	W	Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation
7272	S000006139	ORF	Verified	YPL218W	SAR1	16	138697	139408	W	GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport
7275	S000036529	intron	n.a.	n.a.	n.a.	16	138725	138863	W	n.a.
7276	S000006138	ORF	Verified	YPL217C	BMS1	16	143170	139619	C	Essential conserved nucleolar GTP-binding protein required for synthesis of 40S ribosomal subunits and for processing of the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, has similarity to Tsr1p
7278	S000006137	ORF	Uncharacterized	YPL216W	n.a.	16	143820	147128	W	Hypothetical protein
7280	S000006136	ORF	Verified	YPL215W	CBP3	16	147415	148422	W	Protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); involved in cytochrome-c reductase assembly
7282	S000006135	ORF	Verified	YPL214C	THI6	16	150190	148568	C	Bifunctional enzyme with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities, required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
7284	S000006134	ORF	Verified	YPL213W	LEA1	16	150613	151329	W	Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; putative homolog of human U2A' snRNP protein
7286	S000006133	ORF	Verified	YPL212C	PUS1	16	153148	151514	C	tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA
7288	S000006132	ORF	Verified	YPL211W	NIP7	16	153494	154039	W	Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p
7290	S000006131	ORF	Verified	YPL210C	SRP72	16	156211	154289	C	Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane
7292	S000006130	ORF	Verified	YPL209C	IPL1	16	157592	156489	C	Aurora kinase involved in regulating kinetochore-microtubule attachments, associates with Sli5p, which stimulates Ipl1p kinase activity and promotes its association with the mitotic spindle, potential Cdc28p substrate
7294	S000006129	ORF	Uncharacterized	YPL208W	n.a.	16	157841	159592	W	Hypothetical protein
7296	S000006128	ORF	Uncharacterized	YPL207W	n.a.	16	159908	162340	W	Hypothetical protein
7298	S000006127	ORF	Uncharacterized	YPL206C	n.a.	16	163596	162631	C	Endoplasmic reticulum protein of unknown function
7300	S000006126	ORF	Dubious	YPL205C	n.a.	16	164265	163921	C	Hypothetical protein
7302	S000006125	ORF	Verified	YPL204W	HRR25	16	164275	165759	W	Protein kinase involved in regulating diverse events including vesicular trafficking, gene expression, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta)
7304	S000006124	ORF	Verified	YPL203W	TPK2	16	166255	167397	W	Subunit of cytoplasmic cAMP-dependent protein kinase, which contains redundant catalytic subunits Tpk1p, Tpk2p, and Tpk3p and regulatory subunit Bcy1p; promotes vegetative growth in response to nutrients; activates filamentous growth
7306	S000006123	ORF	Verified	YPL202C	AFT2	16	169337	168087	C	Iron-regulated transcriptional activator, required for iron homeostasis and resistance to oxidative stress; similar to Aft1p
7308	S000006122	ORF	Uncharacterized	YPL201C	n.a.	16	171154	169769	C	Hypothetical protein
7310	S000006121	ORF	Verified	YPL200W	CSM4	16	171483	171953	W	Protein required for accurate chromosome segregation during meiosis
7312	S000006120	ORF	Uncharacterized	YPL199C	n.a.	16	172754	172032	C	Hypothetical protein
7314	S000006119	ORF	Verified	YPL198W	RPL7B	16	173151	174701	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
7318	S000031811	intron	n.a.	n.a.	n.a.	16	173162	173570	W	n.a.
7319	S000031812	intron	n.a.	n.a.	n.a.	16	173665	174071	W	n.a.
7320	S000006450	snoRNA	n.a.	snR59	SNR59	16	173826	173903	W	small nucleolar RNA snR59
7322	S000006118	ORF	Dubious	YPL197C	n.a.	16	174755	174342	C	Hypothetical protein
7324	S000006117	ORF	Verified	YPL196W	OXR1	16	175042	175863	W	Protein of unknown function required for normal levels of resistance to oxidative damage, null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes but not in prokaryotes
7326	S000006116	ORF	Verified	YPL195W	APL5	16	176222	179020	W	Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function
7328	S000006115	ORF	Verified	YPL194W	DDC1	16	179276	181114	W	DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate
7330	S000006114	ORF	Verified	YPL193W	RSA1	16	181402	182547	W	Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly
7332	S000006113	ORF	Verified	YPL192C	PRM3	16	183055	182654	C	Pheromone-regulated protein required for karyogamy; localizes to the inner membrane of the nuclear envelope
7334	S000006112	ORF	Uncharacterized	YPL191C	n.a.	16	184678	183596	C	Hypothetical protein
7336	S000006111	ORF	Verified	YPL190C	NAB3	16	187724	185316	C	Single stranded DNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p
7338	S000028527	ORF	Uncharacterized	YPL189C-A	n.a.	16	188512	188306	C	Identified by homology to <i>Ashbya gossypii</i>
7340	S000006110	ORF	Verified	YPL189W	GUP2	16	189153	190982	W	Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog
7342	S000006109	ORF	Verified	YPL188W	POS5	16	191405	192649	W	Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress
7344	S000006108	ORF	Verified	YPL187W	MF(ALPHA)1	16	193647	194144	W	Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor
7346	S000006106	ORF	Dubious	YPL185W	n.a.	16	195252	195647	W	Hypothetical protein
7348	S000006107	ORF	Verified	YPL186C	UIP4	16	195425	194511	C	Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates
7350	S000006105	ORF	Uncharacterized	YPL184C	n.a.	16	197787	195949	C	Hypothetical protein
7352	S000007224	ORF	Uncharacterized	YPL183W-A	n.a.	16	199094	199375	W	Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome
7354	S000006104	ORF	Uncharacterized	YPL183C	n.a.	16	202535	199494	C	Hypothetical protein
7356	S000006102	ORF	Verified	YPL181W	CTI6	16	203420	204940	W	Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain
7358	S000006103	ORF	Dubious	YPL182C	n.a.	16	203688	203305	C	Hypothetical protein
7360	S000006101	ORF	Verified	YPL180W	TCO89	16	205247	207646	W	Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates growth in response to nutrient availability; cooperates with Ssd1p in the maintenance of cellular integrity; deletion strains are hypersensitive to rapamycin
7362	S000006100	ORF	Verified	YPL179W	PPQ1	16	208156	209805	W	Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors
7364	S000006561	tRNA	n.a.	tE(UUC)P	n.a.	16	210262	210191	C	tRNA-Glu
7368	S000006099	ORF	Verified	YPL178W	CBC2	16	212157	212783	W	Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif
7370	S000006098	ORF	Verified	YPL177C	CUP9	16	213961	213041	C	Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription
7372	S000006097	ORF	Uncharacterized	YPL176C	n.a.	16	218362	216011	C	Plasma membrane localized protein of unknown function; contains sequence similarity to the transferrin receptor
7374	S000006096	ORF	Verified	YPL175W	SPT14	16	218629	220087	W	UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins
7377	S000032482	intron	n.a.	n.a.	n.a.	16	218646	218745	W	n.a.
7378	S000006095	ORF	Verified	YPL174C	NIP100	16	222772	220166	C	Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)
7380	S000006094	ORF	Verified	YPL173W	MRPL40	16	223142	224035	W	Mitochondrial ribosomal protein of the large subunit
7382	S000006093	ORF	Verified	YPL172C	COX10	16	225740	224352	C	Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders
7384	S000006092	ORF	Verified	YPL171C	OYE3	16	227370	226168	C	Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism
7386	S000006091	ORF	Verified	YPL170W	DAP1	16	228313	228771	W	Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis
7388	S000006090	ORF	Verified	YPL169C	MEX67	16	230837	229038	C	Poly(A)RNA binding protein involved in nuclear mRNA export, component of the nuclear pore; ortholog of human TAP
7390	S000006089	ORF	Uncharacterized	YPL168W	n.a.	16	231216	232508	W	Hypothetical protein
7392	S000006088	ORF	Verified	YPL167C	REV3	16	237106	232592	C	Subunit of DNA polymerase zeta, which is involved in DNA repair; required for mutagenesis induced by DNA damage
7394	S000006087	ORF	Uncharacterized	YPL166W	n.a.	16	237337	237978	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
7396	S000006086	ORF	Verified	YPL165C	SET6	16	239076	237955	C	Protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability
7398	S000006085	ORF	Verified	YPL164C	MLH3	16	241496	239349	C	Protein involved in DNA mismatch repair; forms a complex with Mlh1p to promote meiotic crossing-over; mammalian homolog is implicated mammalian microsatellite instability
7400	S000006084	ORF	Verified	YPL163C	SVS1	16	242699	241917	C	Cell wall and vacuolar protein, required for wild-type resistance to vanadate
7402	S000006083	ORF	Uncharacterized	YPL162C	n.a.	16	244026	243205	C	Hypothetical protein
7404	S000006082	ORF	Verified	YPL161C	BEM4	16	246219	244318	C	Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p
7406	S000006081	ORF	Verified	YPL160W	CDC60	16	246989	250261	W	Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA
7408	S000006080	ORF	Uncharacterized	YPL159C	PET20	16	251667	250906	C	Protein required for respiratory growth and stability of the mitochondrial genome
7410	S000006079	ORF	Uncharacterized	YPL158C	n.a.	16	254309	252033	C	Hypothetical protein
7412	S000006078	ORF	Verified	YPL157W	TGS1	16	254813	255760	W	Trimethyl guanosine synthase, conserved nucleolar methyl transferase responsible for conversion of the m(7)G cap structure of snRNAs and snoRNAs to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology
7414	S000006077	ORF	Verified	YPL156C	PRM4	16	256766	255912	C	Pheromone-regulated protein, predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift
7416	S000006076	ORF	Verified	YPL155C	KIP2	16	259335	257215	C	Kinesin-related motor protein involved in mitotic spindle positioning
7418	S000006075	ORF	Verified	YPL154C	PEP4	16	260930	259713	C	Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; synthesized as a zymogen, self-activates
7420	S000006074	ORF	Verified	YPL153C	RAD53	16	264191	261726	C	Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p
7422	S000028721	ORF	Uncharacterized	YPL152W-A	n.a.	16	264601	264699	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7424	S000006073	ORF	Verified	YPL152W	RRD2	16	265027	266103	W	Activator of the phosphotyrosyl phosphatase activity of PP2A; regulates G1 phase progression, the osmoresponse and microtubule dynamics; implicated in the spindle assembly check; subunit of the Tap42p-Pph21p-Rrd2p complex
7426	S000006072	ORF	Verified	YPL151C	PRP46	16	267534	266179	C	Splicing factor that is found in the Cef1p subcomplex of the spliceosome
7428	S000006071	ORF	Uncharacterized	YPL150W	n.a.	16	268187	270892	W	Hypothetical protein
7430	S000006070	ORF	Verified	YPL149W	ATG5	16	271309	272193	W	Conserved autophagy-related protein that undergoes conjugation with Atg12p and then associates with Atg16p to form a cytosolic complex essential for autophagosome formation
7432	S000006069	ORF	Verified	YPL148C	PPT2	16	272814	272293	C	Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation
7434	S000006068	ORF	Verified	YPL147W	PXA1	16	273254	275866	W	Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins
7436	S000006067	ORF	Verified	YPL146C	NOP53	16	277528	276161	C	Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired
7438	S000006066	ORF	Verified	YPL145C	KES1	16	279698	278394	C	Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex
7440	S000006065	ORF	Uncharacterized	YPL144W	n.a.	16	280479	280925	W	Hypothetical protein
7442	S000007441	snoRNA	n.a.	snR17b	SNR17B	16	281516	281055	C	encodes snoRNA U3, SNR17A also encodes snoRNA U3; part of small (ribosomal) subunit (SSU) processosome (contains U3 snoRNA); encodes snoRNA U3, SNR17A also encodes snoRNA U3
7443	S000030181	intron	n.a.	n.a.	n.a.	16	281502	281373	C	n.a.
7446	S000006064	ORF	Verified	YPL143W	RPL33A	16	282121	282969	W	N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable
7449	S000035519	intron	n.a.	n.a.	n.a.	16	282140	282664	W	n.a.
7450	S000006063	ORF	Dubious	YPL142C	n.a.	16	283002	282685	C	Protein required for cell viability
7452	S000006062	ORF	Uncharacterized	YPL141C	n.a.	16	286060	283463	C	Hypothetical protein
7454	S000006061	ORF	Verified	YPL140C	MKK2	16	289033	287513	C	Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p
7456	S000006060	ORF	Verified	YPL139C	UME1	16	291050	289668	C	Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p
7458	S000006059	ORF	Verified	YPL138C	SPP1	16	292426	291365	C	Subunit of COMPASS (Set1C), a complex which methylates Rad6p ubiquitinated histone H3 on lysine 4 and is required in telomeric transcriptional silencing; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein
7460	S000006057	ORF	Dubious	YPL136W	n.a.	16	296285	296653	W	Hypothetical protein
7462	S000006058	ORF	Uncharacterized	YPL137C	n.a.	16	296646	292816	C	Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus
7464	S000006056	ORF	Verified	YPL135W	ISU1	16	297552	298049	W	Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable
7466	S000028720	ORF	Dubious	YPL135C-A	n.a.	16	297850	297677	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
7468	S000006055	ORF	Verified	YPL134C	ODC1	16	299502	298570	C	Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism
7470	S000006054	ORF	Verified	YPL133C	RDS2	16	301227	299887	C	Zinc cluster protein involved in conferring resistance to ketoconazole
7472	S000006053	ORF	Verified	YPL132W	COX11	16	301715	302617	W	Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p
7474	S000006052	ORF	Verified	YPL131W	RPL5	16	303120	304013	W	Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins; binds 5S rRNA and is required for 60S subunit assembly
7476	S000006051	ORF	Verified	YPL130W	SPO19	16	304386	305057	W	Meiosis-specific protein of unknown function, involved in completion of nuclear divisions; identified as a weak high-copy suppressor of the spo1-1 ts mutation; putative GPI-dependent cell-wall protein
7478	S000006050	ORF	Verified	YPL129W	TAF14	16	305297	306136	W	Subunit (30 kDa) of TFIID, TFIIF, and SWI/SNF complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, contains a YEATS domain
7481	S000031308	intron	n.a.	n.a.	n.a.	16	305306	305410	W	n.a.
7482	S000006049	ORF	Verified	YPL128C	TBF1	16	308220	306532	C	Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation
7484	S000006048	ORF	Verified	YPL127C	HHO1	16	309603	308827	C	Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation
7486	S000006047	ORF	Verified	YPL126W	NAN1	16	310209	312899	W	U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA
7488	S000006046	ORF	Verified	YPL125W	KAP120	16	313387	316485	W	Karyopherin with a role in the assembly or export of 60S ribosomal subunits
7490	S000006045	ORF	Verified	YPL124W	SPC29	16	316754	317515	W	Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication
7492	S000006044	ORF	Verified	YPL123C	RNY1	16	318944	317640	C	RNAse; member of the T(2) family of endoribonucleases
7494	S000006043	ORF	Verified	YPL122C	TFB2	16	320766	319225	C	Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH
7496	S000006042	ORF	Verified	YPL121C	MEI5	16	321629	320961	C	Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p
7498	S000006041	ORF	Verified	YPL120W	VPS30	16	322070	323743	W	Protein that forms a membrane-associated complex with Apg14p that is essential for autophagy; involved in a retrieval step of the carboxypeptidase Y receptor, Vps10p, to the late Golgi from the endosome; involved in vacuolar protein sorting
7500	S000028859	ORF	Uncharacterized	YPL119C-A	n.a.	16	324286	324023	C	Identified by expression profiling and mass spectrometry
7502	S000006040	ORF	Verified	YPL119C	DBP1	16	326263	324410	C	Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs
7504	S000006039	ORF	Verified	YPL118W	MRP51	16	326627	327661	W	Mitochondrial ribosomal protein of the large subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences
7506	S000006038	ORF	Verified	YPL117C	IDI1	16	328729	327863	C	Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase), catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability
7508	S000006037	ORF	Verified	YPL116W	HOS3	16	329605	331698	W	Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats
7510	S000006036	ORF	Verified	YPL115C	BEM3	16	335485	332099	C	Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly
7512	S000006035	ORF	Dubious	YPL114W	n.a.	16	335947	336366	W	Hypothetical protein
7514	S000006034	ORF	Uncharacterized	YPL113C	n.a.	16	337142	335952	C	Putative dehydrogenase
7516	S000006033	ORF	Verified	YPL112C	PEX25	16	338619	337435	C	Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p
7518	S000006667	tRNA	n.a.	tM(CAU)P	IMT2	16	338918	338847	C	Initiator methionine tRNA, tRNA(IMet), one of four initiator methionine tRNA genes in yeast that are functional for translation
7520	S000006032	ORF	Verified	YPL111W	CAR1	16	339943	340944	W	Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance
7522	S000006031	ORF	Uncharacterized	YPL110C	n.a.	16	344738	341067	C	Hypothetical protein
7524	S000006030	ORF	Uncharacterized	YPL109C	n.a.	16	347388	345263	C	Hypothetical protein
7527	S000032180	intron	n.a.	n.a.	n.a.	16	345595	345444	C	n.a.
7528	S000006029	ORF	Uncharacterized	YPL108W	n.a.	16	348443	348949	W	Hypothetical protein
7530	S000006028	ORF	Uncharacterized	YPL107W	n.a.	16	349116	349862	W	Hypothetical protein
7532	S000006027	ORF	Verified	YPL106C	SSE1	16	352272	350191	C	ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm
7534	S000006026	ORF	Uncharacterized	YPL105C	n.a.	16	355409	352860	C	Hypothetical protein
7536	S000006025	ORF	Verified	YPL104W	MSD1	16	355697	357673	W	Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene
7538	S000006024	ORF	Uncharacterized	YPL103C	n.a.	16	359403	357997	C	The authentic, non-tagged protein was localized to the mitochondria
7540	S000006022	ORF	Verified	YPL101W	ELP4	16	360206	361576	W	Elongator protein, part of the HAP subcomplex of Elongator, which is a six-subunit component of the RNA polymerase II holoenzyme; required for Elongator structural integrity and histone acetyltransferase activity
7542	S000006023	ORF	Dubious	YPL102C	n.a.	16	360302	360000	C	Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene ELP4
7544	S000006021	ORF	Verified	YPL100W	ATG21	16	361869	363359	W	Phosphatidylinositol 3,5-bisphosphate-binding protein required for maturation of pro-aminopeptidase I, predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization
7546	S000006020	ORF	Uncharacterized	YPL099C	n.a.	16	364065	363517	C	The authentic, non-tagged protein was localized to the mitochondria
7548	S000006019	ORF	Uncharacterized	YPL098C	n.a.	16	364724	364383	C	Hypothetical protein
7550	S000006018	ORF	Verified	YPL097W	MSY1	16	364949	366427	W	Mitochondrial tyrosyl-tRNA synthetase
7552	S000028423	ORF	Verified	YPL096C-A	ERI1	16	366732	366526	C	Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2p at the ER; component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis
7554	S000006017	ORF	Verified	YPL096W	PNG1	16	366924	368015	W	Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation, localizes to the cytoplasm and nucleus, interacts with the DNA repair protein Rad23p
7556	S000006016	ORF	Uncharacterized	YPL095C	n.a.	16	369438	368068	C	Acyl-coenzymeA:ethanol O-acyltransferase responsible for the major part of short-chain fatty acid ethyl ester production during fermentation
7558	S000006015	ORF	Verified	YPL094C	SEC62	16	370660	369836	C	Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
7560	S000006014	ORF	Verified	YPL093W	NOG1	16	370975	372918	W	Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins
7562	S000006013	ORF	Verified	YPL092W	SSU1	16	373790	375166	W	Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein
7564	S000006012	ORF	Verified	YPL091W	GLR1	16	375499	376950	W	Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione
7566	S000006011	ORF	Verified	YPL090C	RPS6A	16	378392	377288	C	Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein
7569	S000035036	intron	n.a.	n.a.	n.a.	16	378386	377993	C	n.a.
7570	S000006010	ORF	Verified	YPL089C	RLM1	16	381147	379117	C	MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p
7572	S000006009	ORF	Uncharacterized	YPL088W	n.a.	16	381962	382990	W	Putative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
7574	S000006008	ORF	Verified	YPL087W	YDC1	16	383452	384405	W	Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity
7576	S000006007	ORF	Verified	YPL086C	ELP3	16	386443	384770	C	Histone acetyltransferase subunit of the Elongator complex, which is a component of the RNA polymerase II holoenzyme; activity is directed specifically towards histones H3 and H4; disruption confers resistance to K. lactis zymotoxin
7578	S000006006	ORF	Verified	YPL085W	SEC16	16	387064	393651	W	COPII vesicle coat protein required for ER transport vesicle budding and autophagosome formation; Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p
7580	S000006005	ORF	Verified	YPL084W	BRO1	16	394035	396569	W	Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes
7582	S000006004	ORF	Verified	YPL083C	SEN54	16	398102	396699	C	Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p
7584	S000006003	ORF	Verified	YPL082C	MOT1	16	404080	398477	C	Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity
7586	S000006002	ORF	Verified	YPL081W	RPS9A	16	404947	406041	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins
7589	S000032633	intron	n.a.	n.a.	n.a.	16	404954	405454	W	n.a.
7590	S000006001	ORF	Dubious	YPL080C	n.a.	16	406495	406169	C	Hypothetical protein
7592	S000006000	ORF	Verified	YPL079W	RPL21B	16	406633	407536	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Ap and has similarity to rat L21 ribosomal protein
7595	S000031937	intron	n.a.	n.a.	n.a.	16	406644	407064	W	n.a.
7596	S000005999	ORF	Verified	YPL078C	ATP4	16	408741	408007	C	Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
7598	S000005998	ORF	Uncharacterized	YPL077C	n.a.	16	410087	409365	C	Hypothetical protein
7600	S000005997	ORF	Verified	YPL076W	GPI2	16	410440	411282	W	Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein
7602	S000005996	ORF	Verified	YPL075W	GCR1	16	412251	415359	W	Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p
7605	S000036780	intron	n.a.	n.a.	n.a.	16	412259	413009	W	n.a.
7606	S000005995	ORF	Verified	YPL074W	YTA6	16	415760	418024	W	Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells
7608	S000005993	ORF	Verified	YPL072W	UBP16	16	418509	420008	W	Putative ubiquitin-specific protease
7610	S000005994	ORF	Dubious	YPL073C	n.a.	16	418981	418496	C	Hypothetical protein
7612	S000005992	ORF	Uncharacterized	YPL071C	n.a.	16	420515	420045	C	Hypothetical protein
7614	S000005991	ORF	Uncharacterized	YPL070W	MUK1	16	420945	422783	W	Protein of unknown function, localized to the cytoplasm; computational analysis of large-scale protein-protein interaction data suggests a possible role in transcriptional regulation
7616	S000005990	ORF	Verified	YPL069C	BTS1	16	423889	422882	C	Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic
7618	S000005989	ORF	Uncharacterized	YPL068C	n.a.	16	425093	424212	C	Hypothetical protein
7620	S000005988	ORF	Uncharacterized	YPL067C	n.a.	16	425844	425248	C	Hypothetical protein
7622	S000005987	ORF	Uncharacterized	YPL066W	n.a.	16	426230	427669	W	Hypothetical protein
7624	S000005986	ORF	Verified	YPL065W	VPS28	16	427924	428652	W	Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; involved in transport of precursors for soluble vacuolar hydrolases from the late endosome to the vacuole
7626	S000005985	ORF	Verified	YPL064C	CWC27	16	429613	428708	C	Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p
7628	S000005984	ORF	Verified	YPL063W	TIM50	16	429936	431366	W	Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may promote binding of incoming precursor proteins to the intermembrane space domain of Tom22p during translocation
7630	S000005983	ORF	Dubious	YPL062W	n.a.	16	431892	432296	W	Hypothetical protein
7632	S000005982	ORF	Verified	YPL061W	ALD6	16	432585	434087	W	Cytosolic aldehyde dehydrogenase that is activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for the conversion of acetaldehyde to acetate; constitutively expressed
7634	S000005981	ORF	Verified	YPL060W	LPE10	16	434520	435761	W	Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p
7636	S000006528	tRNA	n.a.	tC(GCA)P1	n.a.	16	435961	435890	C	tRNA-Cys
7646	S000005980	ORF	Verified	YPL059W	GRX5	16	444576	445028	W	Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p
7648	S000005979	ORF	Verified	YPL058C	PDR12	16	450374	445839	C	Plasma membrane weak-acid-inducible ATP-binding cassette (ABC) transporter, required for weak organic acid resistance, strongly induced by sorbate and benzoate, regulated by War1p, mutants exhibit sorbate hypersensitivity
7650	S000005978	ORF	Verified	YPL057C	SUR1	16	453054	451906	C	Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p
7652	S000005977	ORF	Uncharacterized	YPL056C	n.a.	16	453732	453427	C	Hypothetical protein
7654	S000005976	ORF	Verified	YPL055C	LGE1	16	454987	453989	C	Protein of unknown function; null mutant forms abnormally large cells
7656	S000005975	ORF	Verified	YPL054W	LEE1	16	455756	456661	W	Zinc-finger protein of unknown function
7658	S000005974	ORF	Verified	YPL053C	KTR6	16	458455	457115	C	Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family
7660	S000005973	ORF	Verified	YPL052W	OAZ1	16	459070	459675	W	Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to regulate ubiquitin-independent degradation; ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated
7662	S000005972	ORF	Verified	YPL051W	ARL3	16	459960	460556	W	GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor
7664	S000005971	ORF	Verified	YPL050C	MNN9	16	461963	460776	C	Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation
7666	S000005970	ORF	Verified	YPL049C	DIG1	16	463836	462478	C	Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
7668	S000005969	ORF	Verified	YPL048W	CAM1	16	464398	465645	W	Translational cofactor elongation factor-1 gamma, participates in the regulation of GTP-binding protein EF-1 alpha, may play a redundant role in the regulation of protein synthesis or another GTP-dependent process
7670	S000005968	ORF	Verified	YPL047W	SGF11	16	465959	466258	W	Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation
7672	S000005967	ORF	Verified	YPL046C	ELC1	16	466940	466641	C	Elongin C, forms heterodimer with Ela1p that participates in transcription elongation; expression dramatically upregulated during sporulation; widely conserved among eukaryotes
7674	S000005966	ORF	Verified	YPL045W	VPS16	16	467257	469653	W	Subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; part of the Class C Vps complex essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport
7676	S000005964	ORF	Verified	YPL043W	NOP4	16	469936	471993	W	Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs)
7678	S000005965	ORF	Dubious	YPL044C	n.a.	16	470471	469923	C	Protein required for cell viability
7680	S000005963	ORF	Verified	YPL042C	SSN3	16	474704	473037	C	Component of RNA polymerase II holoenzyme, involved in RNA pol II carboxy-terminal domain phosphorylation
7682	S000005962	ORF	Uncharacterized	YPL041C	n.a.	16	475738	475115	C	Hypothetical protein
7684	S000005961	ORF	Verified	YPL040C	ISM1	16	478998	475990	C	Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth
7686	S000005960	ORF	Uncharacterized	YPL039W	n.a.	16	479222	480172	W	Hypothetical protein
7688	S000028588	ORF	Uncharacterized	YPL038W-A	n.a.	16	480179	480370	W	Identified by fungal homology and RT-PCR
7690	S000005959	ORF	Verified	YPL038W	MET31	16	480532	481065	W	Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met32p
7692	S000005958	ORF	Verified	YPL037C	EGD1	16	481898	481425	C	Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b
7694	S000005957	ORF	Verified	YPL036W	PMA2	16	482841	485684	W	Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential
7696	S000005955	ORF	Uncharacterized	YPL034W	n.a.	16	486710	487207	W	Hypothetical protein
7698	S000005956	ORF	Dubious	YPL035C	n.a.	16	486909	486562	C	Hypothetical protein
7700	S000005954	ORF	Uncharacterized	YPL033C	n.a.	16	488205	487360	C	Hypothetical protein
7702	S000005953	ORF	Verified	YPL032C	SVL3	16	491362	488885	C	Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck
7704	S000005952	ORF	Verified	YPL031C	PHO85	16	493035	492016	C	Cyclin-dependent kinase, with ten cyclin partners; involved in environmental stress response; in phosphate-rich conditions, Pho85p-Pho80p complex phosphorylates Pho4p which in turn represses PHO5
7707	S000029950	intron	n.a.	n.a.	n.a.	16	493018	492917	C	n.a.
7708	S000005951	ORF	Uncharacterized	YPL030W	n.a.	16	493541	495244	W	Hypothetical protein
7710	S000005950	ORF	Verified	YPL029W	SUV3	16	495504	497717	W	ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Msu1p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs
7712	S000005949	ORF	Verified	YPL028W	ERG10	16	498094	499290	W	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis
7714	S000005948	ORF	Verified	YPL027W	SMA1	16	499663	500400	W	Protein of unknown function involved in the assembly of the prospore membrane during sporulation
7716	S000005947	ORF	Verified	YPL026C	SKS1	16	502181	500673	C	Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway
7718	S000005946	ORF	Dubious	YPL025C	n.a.	16	503028	502471	C	Hypothetical protein
7720	S000005945	ORF	Verified	YPL024W	RMI1	16	503515	504240	W	Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III)
7722	S000005944	ORF	Verified	YPL023C	MET12	16	506310	504337	C	Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
7724	S000005943	ORF	Verified	YPL022W	RAD1	16	506695	509997	W	Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein
7726	S000005942	ORF	Verified	YPL021W	ECM23	16	511099	511662	W	Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p
7728	S000005941	ORF	Verified	YPL020C	ULP1	16	514176	512311	C	Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates;  specifically required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase
7730	S000005940	ORF	Verified	YPL019C	VTC3	16	517016	514509	C	Phosphate metabolism; transcription is regulated by PHO system; polyphosphate synthetase (putative)
7732	S000005939	ORF	Verified	YPL018W	CTF19	16	517649	518758	W	Outer kinetochore protein, required for accurate mitotic chromosome segregation; forms a complex with Mcm21p and Okp1p that binds to centromeres via the CBF3 complex
7734	S000005938	ORF	Uncharacterized	YPL017C	n.a.	16	520231	518732	C	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
7736	S000005937	ORF	Verified	YPL016W	SWI1	16	521011	524955	W	One of 11 subunits of the SWI/SNF chromatin remodeling complex that regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2
7738	S000005936	ORF	Verified	YPL015C	HST2	16	526880	525807	C	Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro
7740	S000005935	ORF	Uncharacterized	YPL014W	n.a.	16	527544	528689	W	Hypothetical protein
7742	S000005934	ORF	Verified	YPL013C	MRPS16	16	529347	528982	C	Mitochondrial ribosomal protein of the small subunit
7744	S000005933	ORF	Verified	YPL012W	RRP12	16	529720	533406	W	Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats
7746	S000005932	ORF	Verified	YPL011C	TAF3	16	534700	533639	C	TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation
7748	S000005931	ORF	Verified	YPL010W	RET3	16	535015	535584	W	Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER
7750	S000005930	ORF	Uncharacterized	YPL009C	n.a.	16	538933	535817	C	Hypothetical protein
7752	S000005929	ORF	Verified	YPL008W	CHL1	16	539382	541967	W	Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p
7754	S000005928	ORF	Verified	YPL007C	TFC8	16	543845	542079	C	One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90
7756	S000005927	ORF	Verified	YPL006W	NCR1	16	544628	548140	W	Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein homologous to human Niemann Pick C1 (NPC) protein
7758	S000005926	ORF	Verified	YPL005W	AEP3	16	548483	550303	W	Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex
7760	S000005925	ORF	Verified	YPL004C	LSP1	16	551654	550629	C	Long chain base-responsive inhibitor of protein kinases Phk1p and Phk2p, acts along with Pil1p to down-regulate heat stress resistance via regulation of the Pkc1p and Ypk1p pathways; phosphorylated by Phk1p and Phk2p
7762	S000005924	ORF	Verified	YPL003W	ULA1	16	552017	553405	W	Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation
7764	S000005923	ORF	Verified	YPL002C	SNF8	16	554325	553624	C	Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression
7766	S000005922	ORF	Verified	YPL001W	HAT1	16	554602	555726	W	Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair
7772	S000006205	ORF	Verified	YPR001W	CIT3	16	556374	557834	W	Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, mitochondrial isozyme involved in the TCA cycle
7774	S000006206	ORF	Verified	YPR002W	PDH1	16	558382	559932	W	Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate
7776	S000006570	tRNA	n.a.	tF(GAA)P1	n.a.	16	560286	560195	C	tRNA-Phe
7777	S000035230	intron	n.a.	n.a.	n.a.	16	560249	560231	C	n.a.
7781	S000007254	ORF	Dubious	YPR002C-A	n.a.	16	560763	560566	C	Similar to probable membrane protein YLR334C and ORF YOL106W
7783	S000006207	ORF	Uncharacterized	YPR003C	n.a.	16	563765	561501	C	Hypothetical protein
7785	S000006208	ORF	Uncharacterized	YPR004C	n.a.	16	565038	564004	C	Hypothetical protein
7787	S000006209	ORF	Verified	YPR005C	HAL1	16	566668	565784	C	Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p
7789	S000006210	ORF	Verified	YPR006C	ICL2	16	568993	567266	C	2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol
7791	S000006211	ORF	Verified	YPR007C	REC8	16	571375	569333	C	Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p
7794	S000006588	tRNA	n.a.	tG(GCC)P1	n.a.	16	572266	572336	W	tRNA-Gly
7796	S000006212	ORF	Verified	YPR008W	HAA1	16	573015	575099	W	Transcriptional activator involved in the transcription of TPO2, HSP30 and other genes encoding membrane stress proteins; despite sequence similarity with the transcription factor Ace1p, it is not subject to metalloregulation
7798	S000006213	ORF	Verified	YPR009W	SUT2	16	576549	577355	W	Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p
7800	S000006214	ORF	Verified	YPR010C	RPA135	16	581193	577582	C	RNA polymerase I subunit A135
7802	S000006628	tRNA	n.a.	tK(CUU)P	n.a.	16	582059	582131	W	tRNA-Lys
7804	S000006215	ORF	Uncharacterized	YPR011C	n.a.	16	584039	583059	C	Hypothetical protein
7806	S000006216	ORF	Dubious	YPR012W	n.a.	16	584306	584560	W	Hypothetical protein
7808	S000006217	ORF	Uncharacterized	YPR013C	n.a.	16	585582	584629	C	Hypothetical protein
7810	S000006218	ORF	Dubious	YPR014C	n.a.	16	587515	587186	C	Hypothetical protein
7812	S000006219	ORF	Uncharacterized	YPR015C	n.a.	16	591023	590280	C	Hypothetical protein
7814	S000006220	ORF	Verified	YPR016C	TIF6	16	593066	592329	C	Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits
7816	S000007630	ORF	Dubious	YPR016W-A	n.a.	16	593093	593353	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
7818	S000006221	ORF	Verified	YPR017C	DSS4	16	593914	593483	C	Nucleotide release factor functioning in the post-Golgi secretory pathway, required for ER-to-Golgi transport, binds zinc, found both on membranes and in the cytosol; guanine nucleotide dissociation stimulator
7820	S000006222	ORF	Verified	YPR018W	RLF2	16	594473	596293	W	Largest subunit (p90) of the Chromatin Assembly Complex (CAF-I) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin
7822	S000006223	ORF	Verified	YPR019W	CDC54	16	596747	599548	W	Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p
7824	S000006224	ORF	Verified	YPR020W	ATP20	16	599867	600214	W	Subunit g of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase
7826	S000006225	ORF	Verified	YPR021C	AGC1	16	603354	600646	C	Mitochondrial transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism, ornithine synthesis, and the malate-aspartate NADH shuttle
7828	S000006226	ORF	Uncharacterized	YPR022C	n.a.	16	607309	603908	C	Hypothetical protein
7830	S000006227	ORF	Verified	YPR023C	EAF3	16	610028	608823	C	Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3
7832	S000006228	ORF	Verified	YPR024W	YME1	16	610478	612721	W	Mitochondrial inner membrane protease of the AAA family, responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover
7834	S000006229	ORF	Verified	YPR025C	CCL1	16	614555	613374	C	Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters
7836	S000006230	ORF	Verified	YPR026W	ATH1	16	615376	619011	W	Vacuolar acid trehalase, required for trehalose utilization
7838	S000006231	ORF	Uncharacterized	YPR027C	n.a.	16	621255	620422	C	Hypothetical protein
7840	S000006571	tRNA	n.a.	tF(GAA)P2	n.a.	16	622628	622537	C	tRNA-Phe
7841	S000035233	intron	n.a.	n.a.	n.a.	16	622591	622573	C	n.a.
7844	S000006232	ORF	Verified	YPR028W	YOP1	16	623524	624199	W	Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpression results in cell death and accumulation of internal cell membranes; regulates vesicular traffic in stressed cells
7847	S000032205	intron	n.a.	n.a.	n.a.	16	623575	623707	W	n.a.
7848	S000006233	ORF	Verified	YPR029C	APL4	16	626964	624466	C	Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport
7850	S000006234	ORF	Verified	YPR030W	CSR2	16	627877	631242	W	Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate
7852	S000006235	ORF	Uncharacterized	YPR031W	n.a.	16	631512	633758	W	Component of the histone acetyltransferase complex
7854	S000006236	ORF	Verified	YPR032W	SRO7	16	634120	637221	W	Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p
7856	S000006237	ORF	Verified	YPR033C	HTS1	16	639016	637376	C	Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence
7858	S000006238	ORF	Verified	YPR034W	ARP7	16	639522	640955	W	Actin-related protein involved in transcriptional regulation; subunit of the chromatin remodeling Snf/Swi complex
7860	S000006239	ORF	Verified	YPR035W	GLN1	16	642205	643317	W	Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation
7862	S000006240	ORF	Verified	YPR036W	VMA13	16	643833	645269	W	Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase
7864	S000028425	ORF	Uncharacterized	YPR036W-A	n.a.	16	645947	646150	W	ORF, Uncharacterized
7866	S000006242	ORF	Dubious	YPR038W	n.a.	16	646833	647192	W	Hypothetical protein
7868	S000006243	ORF	Dubious	YPR039W	n.a.	16	647009	647344	W	Hypothetical protein
7870	S000006241	ORF	Verified	YPR037C	ERV2	16	647035	646445	C	Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER
7872	S000006244	ORF	Verified	YPR040W	TIP41	16	647302	648372	W	Protein involved in regulation of the TOR pathway
7874	S000006245	ORF	Verified	YPR041W	TIF5	16	648701	649918	W	Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation
7876	S000006246	ORF	Verified	YPR042C	PUF2	16	653659	650432	C	Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins
7878	S000006247	ORF	Verified	YPR043W	RPL43A	16	654163	654844	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype
7881	S000030560	intron	n.a.	n.a.	n.a.	16	654165	654567	W	n.a.
7882	S000006248	ORF	Dubious	YPR044C	n.a.	16	654874	654521	C	Hypothetical protein
7884	S000006249	ORF	Uncharacterized	YPR045C	n.a.	16	656549	655137	C	Hypothetical protein
7886	S000006250	ORF	Verified	YPR046W	MCM16	16	656796	657341	W	Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA
7888	S000006251	ORF	Verified	YPR047W	MSF1	16	657526	658935	W	Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase
7890	S000006252	ORF	Verified	YPR048W	TAH18	16	659179	661050	W	Protein with a potential role in DNA replication; displays synthetic lethal genetic interaction with the pol3-13 allele of POL3, which encodes DNA polymerase delta
7892	S000006253	ORF	Verified	YPR049C	ATG11	16	664670	661134	C	Peripheral membrane protein required for delivery of aminopeptidase I (Lap4p) to the vacuole in the cytoplasm-to-vacuole targeting pathway; also required for peroxisomal degradation (pexophagy)
7894	S000006255	ORF	Verified	YPR051W	MAK3	16	664957	665487	W	Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus
7896	S000006254	ORF	Dubious	YPR050C	n.a.	16	665363	664950	C	Hypothetical protein
7898	S000006256	ORF	Verified	YPR052C	NHP6A	16	665971	665690	C	High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Bp; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters
7900	S000006257	ORF	Dubious	YPR053C	n.a.	16	666240	665785	C	Hypothetical protein
7902	S000006258	ORF	Verified	YPR054W	SMK1	16	666277	667443	W	Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for spore morphogenesis
7904	S000006259	ORF	Verified	YPR055W	SEC8	16	667673	670870	W	Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
7906	S000006260	ORF	Verified	YPR056W	TFB4	16	671123	672139	W	Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p
7908	S000006261	ORF	Verified	YPR057W	BRR1	16	672468	673493	W	snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed
7910	S000006262	ORF	Verified	YPR058W	YMC1	16	673748	674671	W	Putative mitochondrial inner membrane transporter, member of the mitochondrial carrier (MCF) family
7912	S000006263	ORF	Dubious	YPR059C	n.a.	16	674697	674311	C	Hypothetical protein
7914	S000006264	ORF	Verified	YPR060C	ARO7	16	675628	674858	C	Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis
7916	S000006265	ORF	Verified	YPR061C	JID1	16	676879	675974	C	Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae
7918	S000006266	ORF	Verified	YPR062W	FCY1	16	677162	677638	W	Cytosine deaminase, involved in salvage pathways of pyrimidine metabolism
7920	S000006267	ORF	Uncharacterized	YPR063C	n.a.	16	678317	677809	C	Hypothetical protein
7923	S000029985	intron	n.a.	n.a.	n.a.	16	678276	678191	C	n.a.
7924	S000006268	ORF	Dubious	YPR064W	n.a.	16	678948	679367	W	Hypothetical protein
7926	S000006269	ORF	Verified	YPR065W	ROX1	16	679690	680796	W	Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity
7928	S000006270	ORF	Verified	YPR066W	UBA3	16	681210	682109	W	Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
7930	S000006271	ORF	Verified	YPR067W	ISA2	16	682217	682774	W	Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations
7932	S000006272	ORF	Verified	YPR068C	HOS1	16	684350	682938	C	Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex
7934	S000006273	ORF	Verified	YPR069C	SPE3	16	685434	684553	C	Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells
7936	S000006274	ORF	Verified	YPR070W	MED1	16	685895	687595	W	Subunit 1 of the Mediator complex essential for transcriptional regulation
7938	S000006275	ORF	Uncharacterized	YPR071W	n.a.	16	688169	688804	W	Hypothetical protein
7940	S000006736	tRNA	n.a.	tS(UGA)P	n.a.	16	689562	689643	W	tRNA-Ser
7942	S000006276	ORF	Verified	YPR072W	NOT5	16	690104	691786	W	Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation
7944	S000006277	ORF	Verified	YPR073C	LTP1	16	692415	691930	C	Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine
7946	S000006278	ORF	Verified	YPR074C	TKL1	16	694835	692793	C	Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
7948	S000007631	ORF	Dubious	YPR074W-A	n.a.	16	695015	695185	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
7950	S000006280	ORF	Dubious	YPR076W	n.a.	16	696473	696847	W	Hypothetical protein
7952	S000006279	ORF	Verified	YPR075C	OPY2	16	696816	695734	C	Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone
7954	S000006281	ORF	Dubious	YPR077C	n.a.	16	697499	697128	C	Hypothetical protein
7956	S000006282	ORF	Uncharacterized	YPR078C	n.a.	16	698262	697144	C	Hypothetical protein
7958	S000006283	ORF	Verified	YPR079W	MRL1	16	698867	700012	W	Membrane protein with similarity to mammalian mannose-6-phosphate receptors, possibly functions as a sorting receptor in the delivery of vacuolar hydrolases
7960	S000006284	ORF	Verified	YPR080W	TEF1	16	700592	701968	W	functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes; translational elongation factor EF-1 alpha
7962	S000006285	ORF	Verified	YPR081C	GRS2	16	703968	702112	C	Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels
7964	S000006286	ORF	Verified	YPR082C	DIB1	16	704654	704223	C	17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA splicing, orthologue of the human U5-specific 15-kDa protein
7966	S000006287	ORF	Verified	YPR083W	MDM36	16	704852	706591	W	Protein required for normal mitochondrial morphology and inheritance
7968	S000006288	ORF	Uncharacterized	YPR084W	n.a.	16	706970	708340	W	Hypothetical protein
7970	S000006289	ORF	Uncharacterized	YPR085C	n.a.	16	709826	708495	C	Protein required for cell viability
7972	S000006290	ORF	Verified	YPR086W	SUA7	16	710099	711136	W	Transcription factor TFIIB, a general transcription factor required for transcription initiation and start site selection by RNA polymerase II
7974	S000006291	ORF	Dubious	YPR087W	VPS69	16	711352	711672	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 85% of ORF overlaps the verified gene SRP54; deletion causes a vacuolar protein sorting defect
7976	S000006292	ORF	Verified	YPR088C	SRP54	16	713026	711401	C	Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain
7978	S000006293	ORF	Uncharacterized	YPR089W	n.a.	16	713273	715939	W	Hypothetical protein
7980	S000006296	ORF	Dubious	YPR092W	n.a.	16	718377	718682	W	Hypothetical protein
7982	S000006295	ORF	Uncharacterized	YPR091C	n.a.	16	718466	716154	C	Hypothetical protein
7984	S000006442	snoRNA	n.a.	snR51	SNR51	16	718804	718698	C	guides 2'-O-methylation on small subunit rRNA at A100 and on large subunit rRNA at U2726; small nucleolar RNA snR51
7986	S000006461	snoRNA	n.a.	snR70	SNR70	16	719049	718885	C	involved in 2'-O-methylation on small subunit rRNA at C1638; small nucleolar RNA snR70
7988	S000007305	snoRNA	n.a.	snR41	SNR41	16	719240	719146	C	Small nucleolar RNA
7990	S000006297	ORF	Verified	YPR093C	ASR1	16	720422	719556	C	Protein involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain
7992	S000006298	ORF	Verified	YPR094W	RDS3	16	720635	720958	W	Zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance
7994	S000006299	ORF	Verified	YPR095C	SYT1	16	724715	721035	C	Guanine nucleotide exchange factor (GEF) for Arf proteins; involved in vesicular transport; suppressor of ypt3 mutations; member of the Sec7-domain family
7996	S000006300	ORF	Dubious	YPR096C	n.a.	16	725142	724840	C	Hypothetical protein
7998	S000006301	ORF	Uncharacterized	YPR097W	n.a.	16	725392	728613	W	Hypothetical protein
8000	S000006302	ORF	Uncharacterized	YPR098C	n.a.	16	729526	728945	C	Hypothetical protein
8003	S000034699	intron	n.a.	n.a.	n.a.	16	729479	729384	C	n.a.
8004	S000006304	ORF	Verified	YPR100W	MRPL51	16	729789	730211	W	Mitochondrial ribosomal protein of the large subunit
8006	S000006303	ORF	Dubious	YPR099C	n.a.	16	730111	729755	C	Hypothetical protein
8008	S000006305	ORF	Verified	YPR101W	SNT309	16	730490	731017	W	Component of a protein complex associated with the splicing factor Prp19p, essential for mRNA splicing
8010	S000006306	ORF	Verified	YPR102C	RPL11A	16	731746	731222	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11
8012	S000006307	ORF	Verified	YPR103W	PRE2	16	732347	733210	W	20S proteasome beta-type subunit, responsible for the chymotryptic activity of the proteasome
8014	S000006308	ORF	Verified	YPR104C	FHL1	16	736431	733621	C	Putative transcriptional regulator with similarity to DNA-binding domain of Drosophila forkhead; required for rRNA processing
8016	S000006309	ORF	Verified	YPR105C	COG4	16	739567	736982	C	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
8018	S000006310	ORF	Verified	YPR106W	ISR1	16	740059	741390	W	Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C
8020	S000006311	ORF	Verified	YPR107C	YTH1	16	742062	741436	C	Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation
8022	S000006312	ORF	Verified	YPR108W	RPN7	16	742452	743741	W	Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits
8024	S000028590	ORF	Uncharacterized	YPR108W-A	n.a.	16	744173	744385	W	Identified by fungal homology and RT-PCR
8026	S000006752	tRNA	n.a.	tT(UGU)P	n.a.	16	744282	744353	W	tRNA-Thr
8028	S000006313	ORF	Uncharacterized	YPR109W	n.a.	16	744687	745571	W	Hypothetical protein
8030	S000006314	ORF	Verified	YPR110C	RPC40	16	746833	745826	C	RNA polymerase subunit, common to RNA polymerase I and III
8032	S000006315	ORF	Verified	YPR111W	DBF20	16	747304	748998	W	Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis
8034	S000006316	ORF	Verified	YPR112C	MRD1	16	751917	749254	C	Essential conserved protein that associates with 35S precursor rRNA and is required for its initial processing at the A(0)-A(2) cleavage sites, shows partial nucleolar localization, contains five consensus RNA-binding domains
8036	S000006317	ORF	Verified	YPR113W	PIS1	16	752255	752917	W	Phosphatidylinositol synthase, required for biosynthesis of phosphatidylinositol, which is a precursor for polyphosphoinositides, sphingolipids, and glycolipid anchors for some of the plasma membrane proteins
8038	S000006318	ORF	Uncharacterized	YPR114W	n.a.	16	753299	754246	W	Hypothetical protein
8040	S000006319	ORF	Uncharacterized	YPR115W	n.a.	16	754875	758126	W	Hypothetical protein
8042	S000006320	ORF	Uncharacterized	YPR116W	n.a.	16	758646	759479	W	Hypothetical protein
8044	S000006321	ORF	Uncharacterized	YPR117W	n.a.	16	760023	767492	W	Hypothetical protein
8046	S000006322	ORF	Verified	YPR118W	n.a.	16	767750	768985	W	Methylthioribose-1-phosphate isomerase, catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway
8048	S000006635	tRNA	n.a.	tK(UUU)P	n.a.	16	769300	769205	C	tRNA-Lys
8049	S000034222	intron	n.a.	n.a.	n.a.	16	769263	769241	C	n.a.
8053	S000006323	ORF	Verified	YPR119W	CLB2	16	771651	773126	W	B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
8055	S000006324	ORF	Verified	YPR120C	CLB5	16	775180	773873	C	B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase
8057	S000006529	tRNA	n.a.	tC(GCA)P2	n.a.	16	775834	775763	C	tRNA-Cys
8062	S000006325	ORF	Verified	YPR121W	THI22	16	778579	780297	W	Protein with similarity to hydroxymethylpyrimidine phosphate kinases; member of a gene family with THI20 and THI21; not required for thiamine biosynthesis
8064	S000006326	ORF	Verified	YPR122W	AXL1	16	782041	785667	W	Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells
8066	S000006328	ORF	Verified	YPR124W	CTR1	16	786204	787424	W	High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels
8068	S000006327	ORF	Dubious	YPR123C	n.a.	16	786571	786137	C	Hypothetical protein
8070	S000006329	ORF	Uncharacterized	YPR125W	n.a.	16	787957	789321	W	Hypothetical protein
8072	S000006330	ORF	Dubious	YPR126C	n.a.	16	789381	789073	C	Hypothetical protein
8074	S000006331	ORF	Uncharacterized	YPR127W	n.a.	16	790079	791116	W	Hypothetical protein
8076	S000006332	ORF	Verified	YPR128C	ANT1	16	792200	791214	C	Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation
8078	S000006333	ORF	Verified	YPR129W	SCD6	16	792683	793732	W	Protein containing an Lsm domain, may bind RNA and have a role in RNA processing; overproduction suppresses a null mutation in CHC1, which encodes the heavy chain of clathrin
8080	S000006334	ORF	Dubious	YPR130C	n.a.	16	793777	793370	C	Hypothetical protein
8082	S000006335	ORF	Verified	YPR131C	NAT3	16	794494	793907	C	Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met
8084	S000006336	ORF	Verified	YPR132W	RPS23B	16	794961	795763	W	Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Ap and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal
8087	S000035961	intron	n.a.	n.a.	n.a.	16	795026	795390	W	n.a.
8088	S000006337	ORF	Verified	YPR133C	IWS1	16	797206	795974	C	Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcriptional elongation factor; metazoan homologs contain an acidic N terminus; mutations in the gene confer an Spt- phenotype
8090	S000006433	ORF	Verified	YPR133W-A	TOM5	16	797553	797705	W	Small mitochondrial outer membrane protein crucial to a binding relay for the import of proteins into mitochondria; subunit on the outer mouth of the TOM channel that accepts precursors from the receptors Tom20p and Tom22p
8092	S000006338	ORF	Verified	YPR134W	MSS18	16	798047	798853	W	Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions
8094	S000006339	ORF	Verified	YPR135W	CTF4	16	799230	802013	W	Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion
8096	S000006341	ORF	Verified	YPR137W	RRP9	16	802355	804076	W	Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein
8098	S000006340	ORF	Dubious	YPR136C	n.a.	16	802833	802321	C	Hypothetical protein
8110	S000006677	tRNA	n.a.	tN(GUU)P	n.a.	16	810672	810745	W	tRNA-Asn
8112	S000006342	ORF	Verified	YPR138C	MEP3	16	812449	810980	C	Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease
8114	S000006343	ORF	Verified	YPR139C	VPS66	16	814054	813152	C	Cytoplasmic protein of unknown function involved in vacuolar protein sorting
8116	S000006344	ORF	Verified	YPR140W	TAZ1	16	814387	815532	W	Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; similar to human tafazzin, which is implicated in Barth syndrome
8118	S000006345	ORF	Verified	YPR141C	KAR3	16	817919	815730	C	Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate
8120	S000006347	ORF	Verified	YPR143W	RRP15	16	818319	819071	W	Nucleolar protein, constituent of pre-60S ribosomal particles; required for processing of the 27S pre-rRNA at the A2 site to yield 5.8S and 25S rRNA
8122	S000006346	ORF	Dubious	YPR142C	n.a.	16	818689	818126	C	Protein required for cell viability
8124	S000006611	tRNA	n.a.	tI(AAU)P1	n.a.	16	819525	819598	W	tRNA-Ile
8126	S000006348	ORF	Verified	YPR144C	NOC4	16	821419	819761	C	Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits
8128	S000006505	snoRNA	n.a.	snR45	SNR45	16	821728	821899	W	Small nucleolar RNA
8130	S000006349	ORF	Verified	YPR145W	ASN1	16	822616	824334	W	Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
8132	S000006350	ORF	Dubious	YPR146C	n.a.	16	825672	825343	C	Hypothetical protein
8134	S000006351	ORF	Uncharacterized	YPR147C	n.a.	16	826555	825641	C	Hypothetical protein
8136	S000006352	ORF	Uncharacterized	YPR148C	n.a.	16	828136	826829	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
8138	S000006353	ORF	Verified	YPR149W	NCE102	16	829914	830435	W	Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)
8140	S000006354	ORF	Dubious	YPR150W	n.a.	16	830995	831516	W	Hypothetical protein
8142	S000006355	ORF	Verified	YPR151C	SUE1	16	831671	831051	C	Mitochondrial protein required for degradation of unstable forms of cytochrome c
8144	S000006356	ORF	Uncharacterized	YPR152C	n.a.	16	833454	832057	C	Hypothetical protein
8146	S000006357	ORF	Uncharacterized	YPR153W	n.a.	16	833807	834241	W	Hypothetical protein
8148	S000006358	ORF	Verified	YPR154W	PIN3	16	834561	835208	W	Protein that induces appearance of [PIN+] prion when overproduced
8150	S000006359	ORF	Verified	YPR155C	NCA2	16	837409	835559	C	Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p
8152	S000006360	ORF	Verified	YPR156C	TPO3	16	839773	837905	C	Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the major facilitator superfamily
8154	S000006361	ORF	Uncharacterized	YPR157W	n.a.	16	841262	842665	W	Hypothetical protein
8156	S000006362	ORF	Uncharacterized	YPR158W	n.a.	16	843258	844016	W	Hypothetical protein
8178	S000006520	tRNA	n.a.	tA(AGC)P	n.a.	16	856898	856970	W	tRNA-Ala
8180	S000006363	ORF	Verified	YPR159W	KRE6	16	857579	859741	W	Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p
8182	S000006589	tRNA	n.a.	tG(GCC)P2	n.a.	16	860375	860445	W	tRNA-Gly
8184	S000028725	ORF	Uncharacterized	YPR159C-A	n.a.	16	860411	860310	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8186	S000006364	ORF	Verified	YPR160W	GPH1	16	861302	864010	W	Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway
8188	S000028860	ORF	Dubious	YPR160W-A	n.a.	16	861930	862010	W	Identified by expression profiling and mass spectrometry
8190	S000028726	ORF	Dubious	YPR160C-A	n.a.	16	862857	862573	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8192	S000006365	ORF	Verified	YPR161C	SGV1	16	866418	864445	C	Cyclin (Bur2p)-dependent protein kinase that functions in transcriptional regulation; phosphorylates the carboxy-terminal domain of Rpo21p, which is the largest subunit of RNA polymerase II; regulated by Cak1p
8194	S000006366	ORF	Verified	YPR162C	ORC4	16	868300	866711	C	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing
8196	S000006367	ORF	Verified	YPR163C	TIF3	16	869951	868641	C	Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA
8198	S000006368	ORF	Verified	YPR164W	MMS1	16	870699	874922	W	Protein likely involved in protection against replication-dependent DNA damage; mutants are sensitive to methyl methanesulfonate (MMS); implicated in regulation of Ty1 transposition
8200	S000006369	ORF	Verified	YPR165W	RHO1	16	875364	875993	W	GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)
8202	S000006370	ORF	Verified	YPR166C	MRP2	16	876625	876278	C	Mitochondrial ribosomal protein of the small subunit
8204	S000006371	ORF	Verified	YPR167C	MET16	16	877628	876843	C	3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism
8206	S000006372	ORF	Verified	YPR168W	NUT2	16	878072	878545	W	Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription
8208	S000006373	ORF	Uncharacterized	YPR169W	n.a.	16	878620	880164	W	Nucleolar protein of unknown function, exhibits a physical interaction with Bre1p
8210	S000006612	tRNA	n.a.	tI(AAU)P2	n.a.	16	880365	880292	C	tRNA-Ile
8214	S000028591	ORF	Dubious	YPR169W-A	n.a.	16	883235	883453	W	Identified by fungal homology and RT-PCR
8216	S000028515	ORF	Dubious	YPR170W-B	n.a.	16	883235	883591	W	Identified based on homology to <i>Ashbya gossypii</i>
8219	S000030286	intron	n.a.	n.a.	n.a.	16	883384	883482	W	n.a.
8220	S000006374	ORF	Dubious	YPR170C	n.a.	16	883314	882979	C	Hypothetical protein
8222	S000028861	ORF	Dubious	YPR170W-A	n.a.	16	883374	883559	W	Identified by expression profiling and mass spectrometry
8224	S000006375	ORF	Verified	YPR171W	BSP1	16	883824	885554	W	Adapter that links synaptojanins Inp2p and Inp53p to the cortical actin cytoskeleton
8226	S000006376	ORF	Uncharacterized	YPR172W	n.a.	16	885792	886394	W	Protein of unknown function, transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
8228	S000006377	ORF	Verified	YPR173C	VPS4	16	887833	886520	C	AAA-type ATPase required for efficient late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; cytoplasmic protein that is also associated with an endosomal compartment
8230	S000006378	ORF	Uncharacterized	YPR174C	n.a.	16	888704	888039	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; potential Cdc28p substrate
8232	S000006379	ORF	Verified	YPR175W	DPB2	16	888970	891039	W	Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate
8234	S000006380	ORF	Verified	YPR176C	BET2	16	892074	891097	C	Beta subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p
8236	S000006382	ORF	Verified	YPR178W	PRP4	16	892328	893725	W	Splicing factor, component of the U4/U6-U5 snRNP complex
8238	S000006381	ORF	Dubious	YPR177C	n.a.	16	892680	892309	C	Protein required for cell viability
8240	S000006383	ORF	Verified	YPR179C	HDA3	16	895760	893793	C	Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda2p
8242	S000006384	ORF	Verified	YPR180W	AOS1	16	895957	897000	W	Nuclear protein that acts as a heterodimer with Uba2p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability
8244	S000006385	ORF	Verified	YPR181C	SEC23	16	899663	897357	C	GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p
8246	S000006386	ORF	Verified	YPR182W	SMX3	16	900190	900450	W	Sm or Sm-like snRNP protein
8248	S000006387	ORF	Verified	YPR183W	DPM1	16	900751	901554	W	Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation
8250	S000006388	ORF	Verified	YPR184W	GDB1	16	902040	906650	W	Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation
8252	S000006389	ORF	Verified	YPR185W	ATG13	16	907214	909430	W	Phosphorylated protein that interacts with Vac8p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway and autophagy
8254	S000006390	ORF	Verified	YPR186C	PZF1	16	911018	909729	C	Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA
8256	S000006391	ORF	Verified	YPR187W	RPO26	16	911253	911796	W	RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit
8259	S000032736	intron	n.a.	n.a.	n.a.	16	911273	911348	W	n.a.
8260	S000006392	ORF	Uncharacterized	YPR188C	MLC2	16	912475	911984	C	Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring
8262	S000006393	ORF	Verified	YPR189W	SKI3	16	912660	916958	W	Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski2p and Ski8p; required for repressing propagation of dsRNA viruses
8264	S000006394	ORF	Verified	YPR190C	RPC82	16	919037	917073	C	RNA polymerase III subunit C82
8266	S000006395	ORF	Verified	YPR191W	QCR2	16	919377	920483	W	Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme
8268	S000006396	ORF	Verified	YPR192W	AQY1	16	921856	922773	W	Water channel that mediates the transport of water across cell membranes and may be involved in freeze tolerance
8270	S000006397	ORF	Verified	YPR193C	HPA2	16	923375	922905	C	Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity
8272	S000006398	ORF	Verified	YPR194C	OPT2	16	926933	924300	C	Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans
8274	S000006399	ORF	Dubious	YPR195C	n.a.	16	928290	927961	C	Hypothetical protein
8276	S000006400	ORF	Uncharacterized	YPR196W	n.a.	16	931372	932784	W	nuclear protein (putative)
8279	S000006402	ORF	Verified	YPR198W	SGE1	16	934030	935661	W	Membrane-associated multidrug transporter, acts as an extrusion permease, member of the drug-resistance protein family within the major facilitator superfamily (MFS), partial multicopy suppressor of gal11 mutations
8281	S000006401	ORF	Dubious	YPR197C	n.a.	16	934457	933894	C	Hypothetical protein
8283	S000006403	ORF	Verified	YPR199C	ARR1	16	939028	938144	C	Transcriptional activator of the bZIP family, required for transcription of genes involved in resistance to arsenic compounds
8285	S000006404	ORF	Verified	YPR200C	ARR2	16	939667	939275	C	Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p
8287	S000006405	ORF	Verified	YPR201W	ARR3	16	939918	941132	W	Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite
8296	S000006406	ORF	Uncharacterized	YPR202W	n.a.	16	943028	943892	W	similar to other subtelomerically-encoded proteins
8299	S000034728	intron	n.a.	n.a.	n.a.	16	943047	943194	W	n.a.
8300	S000006407	ORF	Uncharacterized	YPR203W	n.a.	16	943876	944184	W	Hypothetical protein
8302	S000006408	ORF	Uncharacterized	YPR204W	n.a.	16	944599	947697	W	subtelomerically-encoded DNA helicase
8304	S000028727	ORF	Dubious	YPR204C-A	n.a.	16	947334	946852	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8306	S000007328	tRNA	n.a.	tP(UGG)Q	n.a.	17	731	802	W	tRNA-Pro
8308	S000007257	ORF	Dubious	Q0010	n.a.	17	3952	4338	W	Hypothetical protein
8310	S000007258	ORF	Dubious	Q0017	n.a.	17	4254	4415	W	Hypothetical protein
8312	S000007287	rRNA	n.a.	15S_rRNA	15S_RRNA	17	6546	8194	W	Ribosomal RNA of the small mitochondrial ribosomal subunit; MSU1 allele suppresses ochre stop mutations in mitochondrial protein-coding genes
8314	S000007337	tRNA	n.a.	tW(UCA)Q	n.a.	17	9374	9447	W	tRNA-Trp1
8316	S000007259	ORF	Dubious	Q0032	n.a.	17	11667	11957	W	Hypothetical protein
8318	S000007260	ORF	Verified	Q0045	COX1	17	13818	26701	W	Subunit I of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
8327	S000037028	intron	n.a.	n.a.	n.a.	17	13987	16434	W	n.a.
8328	S000037029	intron	n.a.	n.a.	n.a.	17	16471	18953	W	n.a.
8329	S000037030	intron	n.a.	n.a.	n.a.	17	18992	20507	W	n.a.
8330	S000037031	intron	n.a.	n.a.	n.a.	17	20985	21994	W	n.a.
8331	S000037032	intron	n.a.	n.a.	n.a.	17	22247	23611	W	n.a.
8332	S000037033	intron	n.a.	n.a.	n.a.	17	23747	25317	W	n.a.
8333	S000037034	intron	n.a.	n.a.	n.a.	17	25343	26228	W	n.a.
8334	S000007263	ORF	Verified	Q0060	AI3	17	13818	19996	W	Endonuclease I-SceIII, encoded by a mobile group I intron within the mitochondrial COX1 gene
8337	S000037205	intron	n.a.	n.a.	n.a.	17	13987	18953	W	n.a.
8338	S000007265	ORF	Verified	Q0070	AI5_ALPHA	17	13818	23167	W	Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mitochondrial COX1 gene
8344	S000029866	intron	n.a.	n.a.	n.a.	17	13987	16434	W	n.a.
8345	S000029867	intron	n.a.	n.a.	n.a.	17	16471	18953	W	n.a.
8346	S000029868	intron	n.a.	n.a.	n.a.	17	18992	20507	W	n.a.
8347	S000029869	intron	n.a.	n.a.	n.a.	17	20985	21994	W	n.a.
8348	S000007264	ORF	Verified	Q0065	AI4	17	13818	21935	W	Endonuclease I-SceII, encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity
8352	S000037227	intron	n.a.	n.a.	n.a.	17	13987	18953	W	n.a.
8353	S000037228	intron	n.a.	n.a.	n.a.	17	18992	20507	W	n.a.
8354	S000007262	ORF	Verified	Q0055	AI2	17	13818	18830	W	Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene
8357	S000037127	intron	n.a.	n.a.	n.a.	17	13987	16434	W	n.a.
8358	S000007261	ORF	Verified	Q0050	AI1	17	13818	16322	W	Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene
8360	S000007266	ORF	Uncharacterized	Q0075	AI5_BETA	17	24156	25255	W	Protein of unknown function, encoded within an intron of the mitochondrial COX1 gene; translational initiation codon is predicted to be ATA rather than ATG
8363	S000029883	intron	n.a.	n.a.	n.a.	17	24871	24905	W	n.a.
8364	S000007267	ORF	Verified	Q0080	AAP1	17	27666	27812	W	Subunit 8 of the F0 sector of mitochondrial inner membrane F1-F0 ATP synthase, encoded on the mitochondrial genome
8366	S000007268	ORF	Verified	Q0085	ATP6	17	28487	29266	W	Mitochondrially encoded subunit 6 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
8368	S000007269	ORF	Dubious	Q0092	n.a.	17	30874	31014	W	Hypothetical protein
8370	S000007318	tRNA	n.a.	tE(UUC)Q	n.a.	17	35373	35444	W	tRNA-Glu
8372	S000007270	ORF	Verified	Q0105	COB	17	36540	43647	W	Cytochrome b
8379	S000031171	intron	n.a.	n.a.	n.a.	17	36955	37722	W	n.a.
8380	S000031172	intron	n.a.	n.a.	n.a.	17	37737	39140	W	n.a.
8381	S000031173	intron	n.a.	n.a.	n.a.	17	39218	40840	W	n.a.
8382	S000031174	intron	n.a.	n.a.	n.a.	17	41091	42507	W	n.a.
8383	S000031175	intron	n.a.	n.a.	n.a.	17	42559	43296	W	n.a.
8384	S000007271	ORF	Verified	Q0110	BI2	17	36540	38579	W	Mitochondrial mRNA maturase with a role in splicing, encoded by both exon and intron sequences of partially processed COB mRNA
8387	S000031216	intron	n.a.	n.a.	n.a.	17	36955	37722	W	n.a.
8388	S000007272	ORF	Verified	Q0115	BI3	17	36540	40265	W	Mitochondrial mRNA maturase, forms a complex with Mrs1p to mediate splicing of the bI3 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA
8392	S000031227	intron	n.a.	n.a.	n.a.	17	36955	37722	W	n.a.
8393	S000031228	intron	n.a.	n.a.	n.a.	17	37737	39140	W	n.a.
8394	S000007273	ORF	Verified	Q0120	BI4	17	36540	42251	W	Mitochondrial mRNA maturase, forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA
8399	S000032188	intron	n.a.	n.a.	n.a.	17	36955	37722	W	n.a.
8400	S000032189	intron	n.a.	n.a.	n.a.	17	37737	39140	W	n.a.
8401	S000032190	intron	n.a.	n.a.	n.a.	17	39218	40840	W	n.a.
8402	S000007274	ORF	Verified	Q0130	OLI1	17	46723	46953	W	F0-ATP synthase subunit 9 (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2
8404	S000007333	tRNA	n.a.	tS(UGA)Q2	n.a.	17	48201	48290	W	tRNA-Ser
8406	S000007275	ORF	Verified	Q0140	VAR1	17	48901	50097	W	Mitochondrial ribosomal protein of the small subunit, mitochondrially-encoded; polymorphic in different strains due to variation in number of AAT (asparagine) codons; translated near the mitochondrial inner membrane
8408	S000007276	ORF	Dubious	Q0142	n.a.	17	51052	51228	W	Hypothetical protein
8410	S000007277	ORF	Dubious	Q0143	n.a.	17	51277	51429	W	Hypothetical protein
8412	S000007278	ORF	Dubious	Q0144	n.a.	17	54109	54438	W	Hypothetical protein
8414	S000007288	rRNA	n.a.	21S_rRNA	21S_RRNA	17	58009	62447	W	Mitochondrial 21S rRNA gene; intron encodes the I-SceI DNA endonuclease
8415	S000034078	intron	n.a.	n.a.	n.a.	17	60725	61867	W	n.a.
8418	S000007279	ORF	Verified	Q0160	SCEI	17	61022	61729	W	I-SceI DNA endonuclease, encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene
8420	S000007334	tRNA	n.a.	tT(UGU)Q1	n.a.	17	63862	63937	W	tRNA-Thr
8422	S000007316	tRNA	n.a.	tC(GCA)Q	n.a.	17	64415	64490	W	tRNA-Cys
8424	S000007321	tRNA	n.a.	tH(GUG)Q	n.a.	17	64596	64670	W	tRNA-His
8426	S000007280	ORF	Dubious	Q0182	n.a.	17	65770	66174	W	Hypothetical protein
8428	S000007324	tRNA	n.a.	tL(UAA)Q	n.a.	17	66095	66179	W	tRNA-Leu
8430	S000007329	tRNA	n.a.	tQ(UUG)Q	n.a.	17	66210	66285	W	tRNA-Gln
8432	S000007323	tRNA	n.a.	tK(UUU)Q	n.a.	17	67061	67134	W	tRNA-Lys
8434	S000007331	tRNA	n.a.	tR(UCU)Q1	n.a.	17	67309	67381	W	tRNA-Arg
8436	S000007320	tRNA	n.a.	tG(UCC)Q	n.a.	17	67468	67542	W	tRNA-Gly
8438	S000007317	tRNA	n.a.	tD(GUC)Q	n.a.	17	68322	68396	W	tRNA-Asp
8440	S000007332	tRNA	n.a.	tS(GCU)Q1	n.a.	17	69203	69288	W	tRNA-Ser
8442	S000007330	tRNA	n.a.	tR(ACG)Q2	n.a.	17	69289	69362	W	tRNA-Arg
8444	S000007315	tRNA	n.a.	tA(UGC)Q	n.a.	17	69846	69921	W	tRNA-Ala
8446	S000007322	tRNA	n.a.	tI(GAU)Q	n.a.	17	70162	70237	W	tRNA-Ile
8448	S000007338	tRNA	n.a.	tY(GUA)Q	n.a.	17	70824	70907	W	tRNA-Tyr
8450	S000007327	tRNA	n.a.	tN(GUU)Q	n.a.	17	71433	71503	W	tRNA-Asn
8452	S000007325	tRNA	n.a.	tM(CAU)Q1	n.a.	17	72630	72705	W	tRNA-Met
8454	S000007281	ORF	Verified	Q0250	COX2	17	73758	74513	W	Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
8456	S000007282	ORF	Uncharacterized	Q0255	n.a.	17	74495	75984	W	Hypothetical protein
8460	S000036466	intron	n.a.	n.a.	n.a.	17	75623	75662	W	n.a.
8461	S000036467	intron	n.a.	n.a.	n.a.	17	75873	75903	W	n.a.
8462	S000007319	tRNA	n.a.	tF(GAA)Q	n.a.	17	77431	77505	W	tRNA-Phe
8464	S000007335	tRNA	n.a.	tT(n.a.)Q2	n.a.	17	78162	78089	C	tRNA-Thr
8466	S000007336	tRNA	n.a.	tV(UAC)Q	n.a.	17	78533	78608	W	tRNA-Val
8468	S000007283	ORF	Verified	Q0275	COX3	17	79213	80022	W	Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits
8470	S000007326	tRNA	n.a.	tM(CAU)Q2	n.a.	17	85035	85112	W	tRNA-fMet
8472	S000029023	ncRNA	n.a.	RPM1	RPM1	17	85295	85777	W	RNA component of mitochondrial RNase P, which also contains the protein subunit Rpm2p; Rnase P removes 5' extensions from tRNA precursors
8474	S000007284	ORF	Dubious	Q0297	n.a.	17	85554	85709	W	Hypothetical protein
8477	S000028599	ORF	Dubious	YBL113W-A	n.a.	2	646	1128	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8479	S000002153	ORF	Uncharacterized	YBL113C	n.a.	2	2658	280	C	Hypothetical protein
8481	S000002152	ORF	Uncharacterized	YBL112C	n.a.	2	2899	2582	C	Hypothetical protein
8483	S000002151	ORF	Uncharacterized	YBL111C	n.a.	2	5009	2907	C	Hypothetical protein
8486	S000035859	intron	n.a.	n.a.	n.a.	2	4215	4117	C	n.a.
8487	S000002150	ORF	Dubious	YBL109W	n.a.	2	5790	6125	W	Hypothetical protein
8496	S000007592	ORF	Uncharacterized	YBL108C-A	n.a.	2	7733	7605	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
8498	S000000204	ORF	Dubious	YBL108W	n.a.	2	8177	8482	W	Hypothetical protein
8502	S000007229	ORF	Dubious	YBL107W-A	n.a.	2	9268	9372	W	Similar to TyA and TyB proteins
8505	S000006647	tRNA	n.a.	tL(UAA)B1	n.a.	2	9583	9666	W	tRNA-Leu
8507	S000000203	ORF	Uncharacterized	YBL107C	n.a.	2	10551	9961	C	Hypothetical protein
8509	S000000202	ORF	Verified	YBL106C	SRO77	2	13879	10847	C	Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p
8511	S000000201	ORF	Verified	YBL105C	PKC1	2	17696	14241	C	Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)
8513	S000000200	ORF	Uncharacterized	YBL104C	n.a.	2	21293	18177	C	Hypothetical protein
8515	S000000199	ORF	Verified	YBL103C	RTG3	2	23535	22075	C	Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways
8517	S000000198	ORF	Verified	YBL102W	SFT2	2	24098	24745	W	Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5
8519	S000000197	ORF	Verified	YBL101C	ECM21	2	28299	24946	C	Non-essential protein of unknown function; promoter contains several Gcn4p binding elements
8521	S000028598	ORF	Uncharacterized	YBL100W-C	n.a.	2	28427	28546	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8534	S000006562	tRNA	n.a.	tF(GAA)B	n.a.	2	36395	36485	W	tRNA-Phe
8535	S000035371	intron	n.a.	n.a.	n.a.	2	36432	36449	W	n.a.
8538	S000000195	ORF	Verified	YBL099W	ATP1	2	37050	38687	W	Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
8540	S000000196	ORF	Dubious	YBL100C	n.a.	2	37300	36986	C	Dubious open reading frame
8542	S000000194	ORF	Verified	YBL098W	BNA4	2	39142	40524	W	Kynurenine 3-mono oxygenase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
8544	S000000193	ORF	Verified	YBL097W	BRN1	2	40828	43092	W	Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics
8546	S000000191	ORF	Uncharacterized	YBL095W	n.a.	2	43274	44086	W	Hypothetical protein
8548	S000000192	ORF	Dubious	YBL096C	n.a.	2	43479	43171	C	Hypothetical protein
8550	S000000190	ORF	Dubious	YBL094C	n.a.	2	44094	43762	C	Hypothetical protein
8552	S000000189	ORF	Verified	YBL093C	ROX3	2	44915	44253	C	RNA polymerase II holoenzyme component
8554	S000000188	ORF	Verified	YBL092W	RPL32	2	45975	46367	W	Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing
8556	S000007228	ORF	Verified	YBL091C-A	SCS22	2	47177	46562	C	Protein involved in regulation of phospholipid metabolism; homolog of Scs2p2; similar to D. melanogaster inturned protein
8559	S000037852	intron	n.a.	n.a.	n.a.	2	47143	47056	C	n.a.
8560	S000000187	ORF	Verified	YBL091C	MAP2	2	48625	47360	C	Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p
8562	S000000186	ORF	Verified	YBL090W	MRP21	2	48822	49355	W	Mitochondrial ribosomal protein of the large subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences
8564	S000000185	ORF	Verified	YBL089W	AVT5	2	49571	50950	W	Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
8566	S000000184	ORF	Verified	YBL088C	TEL1	2	59379	51016	C	Protein kinase, primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene
8568	S000000183	ORF	Verified	YBL087C	RPL23A	2	60735	59818	C	Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins
8571	S000030033	intron	n.a.	n.a.	n.a.	2	60693	60190	C	n.a.
8572	S000000182	ORF	Uncharacterized	YBL086C	n.a.	2	62599	61199	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
8574	S000000181	ORF	Verified	YBL085W	BOI1	2	63873	66815	W	Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
8576	S000000180	ORF	Verified	YBL084C	CDC27	2	69442	67166	C	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
8578	S000000179	ORF	Dubious	YBL083C	n.a.	2	70135	69710	C	Hypothetical protein
8580	S000000178	ORF	Verified	YBL082C	ALG3	2	71124	69748	C	Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins
8582	S000000177	ORF	Uncharacterized	YBL081W	n.a.	2	71863	72969	W	Hypothetical protein
8584	S000000176	ORF	Verified	YBL080C	PET112	2	74692	73067	C	Protein required for mitochondrial translation; mutation is functionally complemented by a Bacillus subtilis ortholog
8586	S000000175	ORF	Verified	YBL079W	NUP170	2	75256	79764	W	Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p
8588	S000000174	ORF	Verified	YBL078C	ATG8	2	80728	80375	C	Protein required for autophagy; modified by the serial action of Atg4p, Atg7p, and Atg3p, and conjugated at the C terminus with phosphatidylethanolamine, to become the form essential for generation of autophagosomes
8590	S000000173	ORF	Dubious	YBL077W	n.a.	2	80895	81326	W	Protein required for cell viability
8592	S000000172	ORF	Verified	YBL076C	ILS1	2	84259	81041	C	Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A
8594	S000000171	ORF	Verified	YBL075C	SSA3	2	86446	84497	C	ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm
8596	S000000169	ORF	Dubious	YBL073W	n.a.	2	87644	87955	W	Protein required for cell viability
8598	S000000170	ORF	Verified	YBL074C	AAR2	2	87787	86720	C	Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron
8600	S000006447	snoRNA	n.a.	snR56	SNR56	2	88188	88275	W	guides 2'-O-methylation on small subunit rRNA at G1427; small nucleolar RNA snR56
8602	S000000168	ORF	Verified	YBL072C	RPS8A	2	89123	88521	C	Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein
8604	S000028597	ORF	Uncharacterized	YBL071C-B	n.a.	2	89554	89456	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8606	S000007587	ORF	Verified	YBL071W-A	KTI11	2	89976	90224	W	Protein required, along with Dph1p, Dph2p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Dph2p
8608	S000000167	ORF	Dubious	YBL071C	n.a.	2	90529	90221	C	Hypothetical protein
8610	S000000165	ORF	Verified	YBL069W	AST1	2	90739	92028	W	Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts
8612	S000000166	ORF	Dubious	YBL070C	n.a.	2	90923	90603	C	Hypothetical protein
8614	S000028530	ORF	Dubious	YBL068W-A	n.a.	2	91792	92028	W	Identified by fungal homology and RT-PCR
8616	S000000164	ORF	Verified	YBL068W	PRS4	2	92412	93395	W	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes
8618	S000000163	ORF	Verified	YBL067C	UBP13	2	95884	93641	C	Putative ubiquitin-specific protease
8620	S000000161	ORF	Dubious	YBL065W	n.a.	2	99965	100309	W	Hypothetical protein
8622	S000000162	ORF	Verified	YBL066C	SEF1	2	100117	96671	C	Putative transcription factor, has homolog in Kluyveromyces lactis
8624	S000000160	ORF	Verified	YBL064C	PRX1	2	101158	100373	C	Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; induced during respiratory growth and under conditions of oxidative stress
8626	S000000159	ORF	Verified	YBL063W	KIP1	2	101888	105223	W	Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p
8628	S000000158	ORF	Dubious	YBL062W	n.a.	2	105310	105690	W	Hypothetical protein
8630	S000000157	ORF	Verified	YBL061C	SKT5	2	107408	105318	C	Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation
8632	S000000156	ORF	Uncharacterized	YBL060W	n.a.	2	107934	109997	W	Hypothetical protein
8634	S000007488	ORF	Uncharacterized	YBL059C-A	n.a.	2	110541	110127	C	Hypothetical protein
8637	S000032275	intron	n.a.	n.a.	n.a.	2	110507	110423	C	n.a.
8638	S000000155	ORF	Uncharacterized	YBL059W	n.a.	2	110596	111246	W	Hypothetical protein
8641	S000035394	intron	n.a.	n.a.	n.a.	2	110882	110950	W	n.a.
8642	S000000154	ORF	Verified	YBL058W	SHP1	2	111439	112710	W	UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate
8644	S000000153	ORF	Verified	YBL057C	PTH2	2	113447	112803	C	One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for cell growth
8646	S000000152	ORF	Verified	YBL056W	PTC3	2	113765	115171	W	Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation
8648	S000000151	ORF	Uncharacterized	YBL055C	n.a.	2	116832	115576	C	Hypothetical protein
8650	S000000150	ORF	Uncharacterized	YBL054W	n.a.	2	117592	119169	W	Hypothetical protein
8652	S000000149	ORF	Dubious	YBL053W	n.a.	2	119338	119712	W	Hypothetical protein
8654	S000000148	ORF	Verified	YBL052C	SAS3	2	121877	119382	C	Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality
8656	S000000147	ORF	Verified	YBL051C	PIN4	2	124762	122756	C	Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage
8658	S000000146	ORF	Verified	YBL050W	SEC17	2	125128	126122	W	Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP
8661	S000032146	intron	n.a.	n.a.	n.a.	2	125158	125273	W	n.a.
8662	S000000145	ORF	Uncharacterized	YBL049W	MOH1	2	126831	127247	W	Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase
8664	S000000144	ORF	Dubious	YBL048W	n.a.	2	127302	127613	W	Hypothetical protein
8666	S000000143	ORF	Verified	YBL047C	EDE1	2	132043	127898	C	Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins
8668	S000000142	ORF	Uncharacterized	YBL046W	n.a.	2	132427	133752	W	Hypothetical protein
8670	S000000141	ORF	Verified	YBL045C	COR1	2	135519	134146	C	Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain
8672	S000000140	ORF	Uncharacterized	YBL044W	n.a.	2	136001	136369	W	Hypothetical protein
8674	S000000139	ORF	Verified	YBL043W	ECM13	2	136691	137464	W	Non-essential protein of unknown function
8676	S000000138	ORF	Verified	YBL042C	FUI1	2	140263	138344	C	High affinity uridine permease, localized to the plasma membrane; not involved in uracil transport
8678	S000000137	ORF	Verified	YBL041W	PRE7	2	141250	141975	W	20S proteasome beta-type subunit
8680	S000000136	ORF	Verified	YBL040C	ERD2	2	142871	142115	C	Integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins
8683	S000036162	intron	n.a.	n.a.	n.a.	2	142849	142753	C	n.a.
8684	S000028517	ORF	Uncharacterized	YBL039W-B	n.a.	2	143396	143575	W	Identified by homology to <i>Ashbya gossypii</i>
8686	S000028814	ORF	Dubious	YBL039C-A	n.a.	2	145034	144951	C	Identified by expression profiling and mass spectrometry
8688	S000000135	ORF	Verified	YBL039C	URA7	2	145731	143992	C	Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis
8690	S000000134	ORF	Verified	YBL038W	MRPL16	2	146190	146888	W	Mitochondrial ribosomal protein of the large subunit
8692	S000000133	ORF	Verified	YBL037W	APL3	2	147212	150289	W	Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport
8694	S000000132	ORF	Verified	YBL036C	n.a.	2	151223	150450	C	Single-domain racemase, possibly non-specific due to the lack of the second domain, which presumably determines specificity
8696	S000000131	ORF	Verified	YBL035C	POL12	2	153613	151496	C	B subunit of DNA polymerase alpha-primase complex, required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation
8698	S000000130	ORF	Verified	YBL034C	STU1	2	158392	153851	C	Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles
8700	S000000129	ORF	Verified	YBL033C	RIB1	2	159696	158659	C	GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway
8702	S000000128	ORF	Verified	YBL032W	HEK2	2	160187	161332	W	RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length
8704	S000000127	ORF	Verified	YBL031W	SHE1	2	161702	162718	W	Cytoskeletal protein of unknown function; overexpression causes growth arrest
8706	S000000126	ORF	Verified	YBL030C	PET9	2	164000	163044	C	Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene
8708	S000007591	ORF	Uncharacterized	YBL029C-A	n.a.	2	164775	164491	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; has potential orthologs in Saccharomyces species and in Yarrowia lipolytica
8710	S000000125	ORF	Uncharacterized	YBL029W	n.a.	2	166137	167267	W	Hypothetical protein
8712	S000000124	ORF	Uncharacterized	YBL028C	n.a.	2	167841	167521	C	Hypothetical protein
8714	S000000123	ORF	Verified	YBL027W	RPL19B	2	168426	169379	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal
8717	S000031848	intron	n.a.	n.a.	n.a.	2	168428	168811	W	n.a.
8718	S000000122	ORF	Verified	YBL026W	LSM2	2	170626	171041	W	Component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
8721	S000030860	intron	n.a.	n.a.	n.a.	2	170680	170807	W	n.a.
8722	S000000121	ORF	Verified	YBL025W	RRN10	2	171484	171921	W	subunit of UAF (upstream activation factor); involved in promoting high level transcription of rDNA; Upstream activation factor subunit
8724	S000000120	ORF	Verified	YBL024W	NCL1	2	172537	174591	W	S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120
8726	S000000119	ORF	Verified	YBL023C	MCM2	2	177529	174923	C	Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
8728	S000000118	ORF	Verified	YBL022C	PIM1	2	181278	177877	C	Mitochondrial ATP-dependent protease involved in intramitochondrial proteolysis; involved in degradation of misfolded proteins in mitochondria; required for bigenesis and maintenance of mitochondria
8730	S000000117	ORF	Verified	YBL021C	HAP3	2	182097	181663	C	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding
8732	S000000116	ORF	Verified	YBL020W	RFT1	2	182404	184128	W	Flippase, essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane; mutation is suppressed by expression human p53 protein
8734	S000000115	ORF	Verified	YBL019W	APN2	2	184356	185918	W	Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII
8736	S000000114	ORF	Verified	YBL018C	POP8	2	186477	186001	C	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
8739	S000035954	intron	n.a.	n.a.	n.a.	2	186430	186356	C	n.a.
8740	S000000113	ORF	Verified	YBL017C	PEP1	2	191586	186847	C	Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments
8742	S000000112	ORF	Verified	YBL016W	FUS3	2	192454	193515	W	Mitogen-activated protein kinase involved in mating pheromone response; activated by phoshporylation by Ste7p; provides specificity during the mating vs. filamentous growth response by phosphorylating transcriptional and cytoplasmic targets
8744	S000000111	ORF	Verified	YBL015W	ACH1	2	194125	195705	W	Acetyl-coA hydrolase, primarily localized to mitochondria; required for acetate utilization and for diploid pseudohyphal growth
8747	S000006600	tRNA	n.a.	tI(AAU)B	n.a.	2	197497	197570	W	tRNA-Ile
8749	S000006574	tRNA	n.a.	tG(GCC)B	n.a.	2	197702	197632	C	tRNA-Gly
8752	S000000110	ORF	Verified	YBL014C	RRN6	2	201751	199067	C	involved in the transcription of 35S rRNA genes by RNA polymerase I; member of yeast Pol I core factor (CF) also composed of Rrn11p, Rrn7p and TATA-binding protein
8754	S000000109	ORF	Verified	YBL013W	FMT1	2	202059	203264	W	Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate
8756	S000000107	ORF	Verified	YBL011W	SCT1	2	203541	205820	W	Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed
8758	S000000108	ORF	Dubious	YBL012C	n.a.	2	203810	203409	C	Hypothetical protein
8760	S000000106	ORF	Uncharacterized	YBL010C	n.a.	2	206952	206110	C	Hypothetical protein
8762	S000000105	ORF	Uncharacterized	YBL009W	n.a.	2	207197	209227	W	haspin
8764	S000028529	ORF	Uncharacterized	YBL008W-A	n.a.	2	209412	209651	W	Identified by fungal homology and RT-PCR
8766	S000000104	ORF	Verified	YBL008W	HIR1	2	209656	212178	W	Non-essential transcriptional corepressor involved in the cell cycle-regulated transcription of histone H2A, H2B, H3 and H4 genes; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores
8768	S000000103	ORF	Verified	YBL007C	SLA1	2	216369	212635	C	Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; contains 3 SH3 domains; interacts with proteins regulating actin dynamics and with proteins required for endocytosis
8770	S000028596	ORF	Dubious	YBL006W-A	n.a.	2	216714	216863	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
8772	S000000102	ORF	Verified	YBL006C	LDB7	2	217132	216590	C	Protein of unknown function; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface
8774	S000000101	ORF	Verified	YBL005W	PDR3	2	217473	220403	W	Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)
8786	S000006720	tRNA	n.a.	tS(AGA)B	n.a.	2	227078	227159	W	tRNA-Ser
8788	S000000100	ORF	Uncharacterized	YBL004W	UTP20	2	227639	235120	W	Possible snoRNA-binding protein, based on computational analysis of large-scale protein-protein interaction data
8790	S000000099	ORF	Verified	YBL003C	HTA2	2	235795	235397	C	One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
8792	S000000098	ORF	Verified	YBL002W	HTB2	2	236495	236890	W	One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
8794	S000000097	ORF	Verified	YBL001C	ECM15	2	237469	237155	C	Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis
8800	S000000205	ORF	Verified	YBR001C	NTH2	2	241285	238943	C	Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses
8802	S000000206	ORF	Verified	YBR002C	RER2	2	242570	241710	C	Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting
8804	S000000207	ORF	Verified	YBR003W	COQ1	2	242811	244232	W	Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis
8806	S000000208	ORF	Verified	YBR004C	GPI18	2	245669	244368	C	Functional ortholog of human PIG-V, which is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis; the authentic, non-tagged protein was localized to mitochondria
8808	S000000209	ORF	Verified	YBR005W	RCR1	2	245908	246549	W	Protein of the endoplasmic reticulum membrane involved in chitin deposition in the cell wall; overproduction confers resistance to Congo Red
8810	S000000210	ORF	Verified	YBR006W	UGA2	2	247012	248505	W	Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm
8812	S000000211	ORF	Uncharacterized	YBR007C	n.a.	2	251017	248807	C	ORF, Uncharacterized
8814	S000000212	ORF	Verified	YBR008C	FLR1	2	254210	252564	C	Plasma membrane multidrug transporter, member of the major facilitator superfamily; involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs
8816	S000000213	ORF	Verified	YBR009C	HHF1	2	255682	255371	C	One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity
8818	S000000214	ORF	Verified	YBR010W	HHT1	2	256329	256739	W	One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation
8820	S000000215	ORF	Verified	YBR011C	IPP1	2	257973	257110	C	Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase
8823	S000000216	ORF	Dubious	YBR012C	n.a.	2	259564	259145	C	Hypothetical protein
8834	S000000217	ORF	Uncharacterized	YBR013C	n.a.	2	265879	265490	C	Hypothetical protein
8837	S000006737	tRNA	n.a.	tT(AGU)B	n.a.	2	266378	266450	W	tRNA-Thr
8839	S000000218	ORF	Uncharacterized	YBR014C	n.a.	2	267336	266725	C	Hypothetical protein
8841	S000000219	ORF	Verified	YBR015C	MNN2	2	269503	267710	C	Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment
8843	S000000220	ORF	Uncharacterized	YBR016W	n.a.	2	270247	270633	W	Plasma membrane protein of unknown function; has similarity to hydrophilins, which are hydrophilic, glycine-rich proteins involved in the adaptive response to hyperosmotic conditions
8845	S000000221	ORF	Verified	YBR017C	KAP104	2	273703	270947	C	Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous nuclear ribonucleoproteins to the nucleoplasm, binds rg-nuclear localization signals on Nab2p and Hrp1p, plays a role in cell-cycle progression
8847	S000000222	ORF	Verified	YBR018C	GAL7	2	275527	274427	C	Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism
8849	S000000223	ORF	Verified	YBR019C	GAL10	2	278352	276253	C	UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers
8851	S000000224	ORF	Verified	YBR020W	GAL1	2	279021	280607	W	Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p
8853	S000000225	ORF	Verified	YBR021W	FUR4	2	281443	283344	W	Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues
8855	S000000226	ORF	Verified	YBR022W	POA1	2	283738	284271	W	Phosphatase that is highly specific for ADP-ribose 1''-phosphate, a tRNA splicing metabolite; may have a role in regulation of tRNA splicing
8857	S000000227	ORF	Verified	YBR023C	CHS3	2	287925	284428	C	Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan
8859	S000000228	ORF	Verified	YBR024W	SCO2	2	289445	290350	W	Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p
8861	S000000229	ORF	Uncharacterized	YBR025C	n.a.	2	291865	290681	C	Hypothetical protein
8863	S000000230	ORF	Verified	YBR026C	ETR1	2	294019	292877	C	2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis
8865	S000000231	ORF	Dubious	YBR027C	n.a.	2	294356	294024	C	Hypothetical protein
8867	S000000232	ORF	Uncharacterized	YBR028C	n.a.	2	296002	294425	C	Hypothetical protein
8869	S000000233	ORF	Verified	YBR029C	CDS1	2	297742	296369	C	Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids
8871	S000000234	ORF	Uncharacterized	YBR030W	n.a.	2	298292	299950	W	Hypothetical protein
8873	S000000235	ORF	Verified	YBR031W	RPL4A	2	300166	301254	W	N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins
8875	S000000236	ORF	Dubious	YBR032W	n.a.	2	301519	301821	W	Hypothetical protein
8877	S000000237	ORF	Uncharacterized	YBR033W	n.a.	2	301944	304703	W	Non-essential protein of unknown function
8879	S000000238	ORF	Verified	YBR034C	HMT1	2	305976	304930	C	Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants
8881	S000000239	ORF	Verified	YBR035C	PDX3	2	306955	306269	C	Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism
8883	S000006657	ncRNA	n.a.	TLC1	TLC1	2	307587	308887	W	TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase
8885	S000000240	ORF	Verified	YBR036C	CSG2	2	310313	309081	C	Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations
8887	S000000241	ORF	Verified	YBR037C	SCO1	2	311451	310564	C	Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; has similarity to thioredoxins
8889	S000000242	ORF	Verified	YBR038W	CHS2	2	311897	314788	W	Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis
8891	S000000243	ORF	Verified	YBR039W	ATP3	2	315575	316510	W	Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
8893	S000000244	ORF	Verified	YBR040W	FIG1	2	316968	317864	W	Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating
8895	S000000245	ORF	Verified	YBR041W	FAT1	2	318266	320275	W	Fatty acid transporter and very long-chain fatty acyl-CoA synthetase, may form a complex with Faa1p or Faa4p that imports and activates exogenous fatty acids
8897	S000000246	ORF	Uncharacterized	YBR042C	n.a.	2	321609	320416	C	Hypothetical protein
8899	S000000247	ORF	Verified	YBR043C	QDR3	2	323945	321876	C	Multidrug transporter required for resistance to quinidine, barban, cisplatin, and bleomycin; member of the major facilitator superfamily of transporters conferring multiple drug resistance (MFS-MDR)
8901	S000000248	ORF	Verified	YBR044C	TCM62	2	326058	324337	C	Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone
8903	S000006769	tRNA	n.a.	tV(UAC)B	n.a.	2	326864	326791	C	tRNA-Val
8907	S000000249	ORF	Verified	YBR045C	GIP1	2	330090	328369	C	Meiosis-specific protein proposed to be a regulatory subunit of the protein phosphatase Glc7p, required for spore wall formation and proper septin organization
8909	S000000250	ORF	Verified	YBR046C	ZTA1	2	331509	330505	C	Zeta-crystallin homolog, found in the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin, which has quinone oxidoreductase activity
8911	S000000251	ORF	Uncharacterized	YBR047W	n.a.	2	331831	332358	W	The authentic, non-tagged protein was localized to the mitochondria
8913	S000000252	ORF	Verified	YBR048W	RPS11B	2	332829	333810	W	Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins
8916	S000035810	intron	n.a.	n.a.	n.a.	2	332874	333384	W	n.a.
8917	S000000253	ORF	Verified	YBR049C	REB1	2	336816	334384	C	RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription
8919	S000000255	ORF	Dubious	YBR051W	n.a.	2	337986	338336	W	Hypothetical protein
8921	S000000254	ORF	Verified	YBR050C	REG2	2	338197	337181	C	Protein that binds type 1 protein phosphatase Glc7p; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes
8923	S000000256	ORF	Uncharacterized	YBR052C	n.a.	2	339350	338718	C	Protein of unknown function; member of a flavodoxin-like fold protein family that includes Pst2p and Ycp4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
8925	S000000257	ORF	Uncharacterized	YBR053C	n.a.	2	340749	339673	C	Hypothetical protein
8927	S000000258	ORF	Verified	YBR054W	YRO2	2	343099	344133	W	Putative plasma membrane protein of unknown function, transcriptionally regulated by Haa1p; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud
8929	S000000259	ORF	Verified	YBR055C	PRP6	2	347299	344600	C	Splicing factor, component of the U4/U6-U5 snRNP complex
8931	S000006648	tRNA	n.a.	tL(UAA)B2	n.a.	2	347601	347684	W	tRNA-Leu
8933	S000000260	ORF	Uncharacterized	YBR056W	n.a.	2	347877	349382	W	Hypothetical protein
8936	S000006691	tRNA	n.a.	tQ(UUG)B	n.a.	2	350825	350896	W	tRNA-Gln
8938	S000028736	ORF	Uncharacterized	YBR056W-A	n.a.	2	351253	351453	W	ORF, Uncharacterized
8940	S000000261	ORF	Verified	YBR057C	MUM2	2	353291	352191	C	Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, which is a component of the origin recognition complex
8942	S000000262	ORF	Verified	YBR058C	UBP14	2	356015	353670	C	Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T
8944	S000007521	ORF	Verified	YBR058C-A	TSC3	2	356564	356322	C	Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis
8946	S000000263	ORF	Verified	YBR059C	AKL1	2	360185	356859	C	Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization
8948	S000000264	ORF	Verified	YBR060C	ORC2	2	362512	360650	C	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p
8950	S000000265	ORF	Verified	YBR061C	TRM7	2	365717	364785	C	2'-O-ribose methyltransferase, methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop
8952	S000000266	ORF	Uncharacterized	YBR062C	n.a.	2	366598	365974	C	Hypothetical protein
8955	S000032828	intron	n.a.	n.a.	n.a.	2	366582	366501	C	n.a.
8956	S000000268	ORF	Dubious	YBR064W	n.a.	2	367761	368189	W	Hypothetical protein
8958	S000000267	ORF	Uncharacterized	YBR063C	n.a.	2	368182	366968	C	Hypothetical protein
8960	S000000269	ORF	Verified	YBR065C	ECM2	2	369676	368582	C	Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p
8962	S000000270	ORF	Verified	YBR066C	NRG2	2	370697	370035	C	Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p
8964	S000000271	ORF	Verified	YBR067C	TIP1	2	372732	372100	C	Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins
8966	S000000272	ORF	Verified	YBR068C	BAP2	2	375687	373858	C	High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains
8968	S000000273	ORF	Verified	YBR069C	TAT1	2	378430	376571	C	Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 resistance
8970	S000000274	ORF	Verified	YBR070C	ALG14	2	379931	379218	C	Essential protein required for the second step of dolichyl-linked oligosaccharide synthesis; involved in N-linked glycosylation; similar to bacterial glycosyltransferases
8972	S000000275	ORF	Uncharacterized	YBR071W	n.a.	2	380408	381043	W	Hypothetical protein
8974	S000000276	ORF	Verified	YBR072W	HSP26	2	382027	382671	W	Small heat shock protein with chaperone activity that is regulated by a heat induced transition from an inactive oligomeric (24-mer) complex to an active dimer; induced by heat, upon entry into stationary phase, and during sporulation
8976	S000028532	ORF	Uncharacterized	YBR072C-A	n.a.	2	383016	382855	C	Identified by fungal homology and RT-PCR
8978	S000000277	ORF	Verified	YBR073W	RDH54	2	383209	385983	W	DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during mitosis and meiosis; proposed to be involved in crossover interference
8980	S000000278	ORF	Uncharacterized	YBR074W	n.a.	2	386281	389211	W	Putative metalloprotease
8982	S000000280	ORF	Verified	YBR076W	ECM8	2	390369	391388	W	Non-essential protein of unknown function
8984	S000028533	ORF	Dubious	YBR076C-A	n.a.	2	391611	391345	C	Identified by fungal homology and RT-PCR
8986	S000000281	ORF	Verified	YBR077C	SLM4	2	392287	391799	C	Component of the EGO complex, which is involved in the regulation of microautophagy; gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase
8988	S000000282	ORF	Verified	YBR078W	ECM33	2	393118	394854	W	GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; similar to Sps2p and Pst1p
8991	S000030048	intron	n.a.	n.a.	n.a.	2	393176	393505	W	n.a.
8992	S000000283	ORF	Verified	YBR079C	RPG1	2	398271	395377	C	Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes
8994	S000000284	ORF	Verified	YBR080C	SEC18	2	400884	398608	C	ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF
8996	S000000285	ORF	Verified	YBR081C	SPT7	2	405245	401247	C	Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex
8998	S000006708	tRNA	n.a.	tR(UCU)B	n.a.	2	405872	405943	W	tRNA-Arg
9000	S000006530	tRNA	n.a.	tD(GUC)B	n.a.	2	405954	406025	W	tRNA-Asp
9002	S000000286	ORF	Verified	YBR082C	UBC4	2	407163	406622	C	Ubiquitin-conjugating enzyme that mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response
9005	S000032124	intron	n.a.	n.a.	n.a.	2	407116	407022	C	n.a.
9006	S000000287	ORF	Verified	YBR083W	TEC1	2	409163	410623	W	transcription factor of the TEA/ATTS DNA-binding domain family, regulator of Ty1 expression
9008	S000000288	ORF	Verified	YBR084W	MIS1	2	411048	413975	W	Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase
9010	S000002156	ORF	Verified	YBR084C-A	RPL19A	2	415255	414180	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal
9013	S000033731	intron	n.a.	n.a.	n.a.	2	415253	414748	C	n.a.
9014	S000000289	ORF	Verified	YBR085W	AAC3	2	415977	416900	W	Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Pet9p and Aac1p; has roles in maintenance of viability and in respiration
9016	S000007522	ORF	Uncharacterized	YBR085C-A	n.a.	2	419158	418901	C	Hypothetical protein
9018	S000000290	ORF	Verified	YBR086C	IST2	2	423035	420195	C	Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process
9020	S000000291	ORF	Verified	YBR087W	RFC5	2	423759	424823	W	Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon
9022	S000000293	ORF	Dubious	YBR089W	n.a.	2	425177	425776	W	Hypothetical protein
9024	S000000292	ORF	Verified	YBR088C	POL30	2	425760	424984	C	Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair
9026	S000002157	ORF	Verified	YBR089C-A	NHP6B	2	426483	426184	C	High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters
9028	S000000294	ORF	Uncharacterized	YBR090C	n.a.	2	427052	426327	C	Hypothetical protein
9031	S000035424	intron	n.a.	n.a.	n.a.	2	426867	426511	C	n.a.
9032	S000000295	ORF	Verified	YBR091C	MRS5	2	427478	427149	C	Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins
9034	S000000296	ORF	Verified	YBR092C	PHO3	2	429095	427692	C	Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin
9036	S000000297	ORF	Verified	YBR093C	PHO5	2	430945	429542	C	One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2
9038	S000000298	ORF	Uncharacterized	YBR094W	n.a.	2	432030	434291	W	Hypothetical protein
9040	S000000299	ORF	Uncharacterized	YBR095C	n.a.	2	435692	434400	C	Protein possibly involved in cell fusion and invasive growth
9042	S000000300	ORF	Uncharacterized	YBR096W	n.a.	2	436015	436707	W	Hypothetical protein
9044	S000000301	ORF	Verified	YBR097W	VPS15	2	436945	441309	W	Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; also detected in mitochondria
9046	S000000302	ORF	Verified	YBR098W	MMS4	2	441509	443584	W	Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination and DNA repair
9048	S000000303	ORF	Dubious	YBR099C	n.a.	2	443301	442918	C	Hypothetical protein
9050	S000000305	ORF	Verified	YBR101C	FES1	2	444687	443815	C	Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum
9052	S000000306	ORF	Verified	YBR102C	EXO84	2	447317	445056	C	Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis
9054	S000000307	ORF	Verified	YBR103W	SIF2	2	447703	449310	W	WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus
9056	S000007593	ORF	Dubious	YBR103C-A	n.a.	2	449457	449314	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
9058	S000000308	ORF	Verified	YBR104W	YMC2	2	449661	450650	W	Putative mitochondrial inner membrane transporter, member of the mitochondrial carrier (MCF) family
9060	S000000309	ORF	Verified	YBR105C	VID24	2	451963	450875	C	Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase
9062	S000000310	ORF	Verified	YBR106W	PHO88	2	452652	453218	W	Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations
9064	S000000311	ORF	Verified	YBR107C	IML3	2	454524	453787	C	Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p
9066	S000000312	ORF	Uncharacterized	YBR108W	n.a.	2	454816	457659	W	Protein interacting with Rsv167p
9068	S000000313	ORF	Verified	YBR109C	CMD1	2	458356	457913	C	Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin
9070	S000028737	ORF	Dubious	YBR109W-A	n.a.	2	458602	458826	W	Questionable ORF from MIPS
9072	S000000314	ORF	Verified	YBR110W	ALG1	2	458866	460215	W	Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog
9074	S000000315	ORF	Verified	YBR111C	YSA1	2	461867	461172	C	Protein with weak similarity to D. melanogaster serendipity protein and X. laevis basis fibroblast growth factor
9076	S000028510	ORF	Verified	YBR111W-A	SUS1	2	462133	462573	W	Protein involved in mRNA export coupled transcription activation; component of the SAGA histone acetylase complex
9080	S000030262	intron	n.a.	n.a.	n.a.	2	462204	462283	W	n.a.
9081	S000030264	intron	n.a.	n.a.	n.a.	2	462424	462493	W	n.a.
9082	S000000317	ORF	Dubious	YBR113W	n.a.	2	465560	466042	W	Hypothetical protein
9084	S000000316	ORF	Verified	YBR112C	CYC8	2	465764	462864	C	General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters
9086	S000000318	ORF	Verified	YBR114W	RAD16	2	467242	469614	W	Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4); member of the SWI/SNF family
9088	S000000319	ORF	Verified	YBR115C	LYS2	2	473920	469742	C	Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p
9090	S000000320	ORF	Dubious	YBR116C	n.a.	2	474720	474193	C	Hypothetical protein
9092	S000000321	ORF	Verified	YBR117C	TKL2	2	476431	474386	C	Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids
9094	S000000322	ORF	Verified	YBR118W	TEF2	2	477665	479041	W	functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes; translational elongation factor EF-1 alpha
9096	S000000323	ORF	Verified	YBR119W	MUD1	2	479332	480317	W	U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing
9099	S000034717	intron	n.a.	n.a.	n.a.	2	479340	479428	W	n.a.
9100	S000000324	ORF	Verified	YBR120C	CBP6	2	480917	480429	C	Translational activator of COB mRNA
9102	S000028815	ORF	Dubious	YBR121C-A	n.a.	2	482478	482320	C	Identified by expression profiling and mass spectrometry
9104	S000000325	ORF	Verified	YBR121C	GRS1	2	483361	481358	C	Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation
9106	S000000326	ORF	Verified	YBR122C	MRPL36	2	484497	483964	C	Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region
9108	S000000328	ORF	Dubious	YBR124W	n.a.	2	486501	486860	W	Hypothetical protein
9110	S000000327	ORF	Verified	YBR123C	TFC1	2	486685	484736	C	One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63
9112	S000000329	ORF	Verified	YBR125C	PTC4	2	488374	487193	C	Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of the synthetic lethality of a cnb1 mpk1 double deletion; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity
9114	S000000330	ORF	Verified	YBR126C	TPS1	2	490386	488899	C	Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway
9116	S000028600	ORF	Dubious	YBR126W-A	n.a.	2	490844	491050	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9118	S000028738	ORF	Dubious	YBR126W-B	n.a.	2	490921	491064	W	Identified by SAGE
9120	S000000331	ORF	Verified	YBR127C	VMA2	2	492816	491263	C	Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm
9122	S000000332	ORF	Verified	YBR128C	ATG14	2	494109	493075	C	Subunit of an autophagy-specific phosphatidylinositol 3-kinase complex (with Vps34p, Vps15p, and Vps30p) required for organization of a pre-autophagosomal structure; ATG14 transcription is activated by Gln3p during nitrogen starvation
9124	S000000333	ORF	Verified	YBR129C	OPY1	2	495333	494347	C	Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone
9126	S000000334	ORF	Verified	YBR130C	SHE3	2	496863	495586	C	Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance
9128	S000000335	ORF	Verified	YBR131W	CCZ1	2	497157	499271	W	Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway
9130	S000028601	ORF	Dubious	YBR131C-A	n.a.	2	497733	497644	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9132	S000000336	ORF	Verified	YBR132C	AGP2	2	501436	499646	C	High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease
9134	S000000338	ORF	Dubious	YBR134W	n.a.	2	504237	504638	W	Hypothetical protein
9136	S000000337	ORF	Verified	YBR133C	HSL7	2	504281	501798	C	Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p
9138	S000000339	ORF	Verified	YBR135W	CKS1	2	504848	505300	W	Subunit of the Cdc28 protein kinase, required for mitotic proteolysis, may also be involved in the proteolysis of the G1 cyclins
9140	S000000340	ORF	Verified	YBR136W	MEC1	2	505662	512768	W	Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination
9142	S000000341	ORF	Uncharacterized	YBR137W	n.a.	2	513038	513577	W	Hypothetical protein
9144	S000000342	ORF	Uncharacterized	YBR138C	n.a.	2	515330	513756	C	Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p
9146	S000000343	ORF	Uncharacterized	YBR139W	n.a.	2	515658	517184	W	Hypothetical protein
9148	S000000344	ORF	Verified	YBR140C	IRA1	2	526622	517344	C	GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase
9150	S000028602	ORF	Dubious	YBR141W-A	n.a.	2	527161	527256	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9152	S000000345	ORF	Uncharacterized	YBR141C	n.a.	2	528032	527019	C	Hypothetical protein
9154	S000000346	ORF	Verified	YBR142W	MAK5	2	528311	530632	W	Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits
9156	S000000347	ORF	Verified	YBR143C	SUP45	2	532176	530863	C	Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor
9158	S000000348	ORF	Dubious	YBR144C	n.a.	2	533543	533229	C	Hypothetical protein
9160	S000000349	ORF	Verified	YBR145W	ADH5	2	533756	534811	W	Alcohol dehydrogenase isoenzyme V; involved in ethanol production
9162	S000000350	ORF	Verified	YBR146W	MRPS9	2	535254	536090	W	Mitochondrial ribosomal protein of the small subunit
9164	S000000351	ORF	Uncharacterized	YBR147W	n.a.	2	536569	537459	W	Hypothetical protein
9166	S000000352	ORF	Verified	YBR148W	YSW1	2	537870	539699	W	Protein expressed specifically in spores
9168	S000000353	ORF	Verified	YBR149W	ARA1	2	539981	541015	W	Large subunit of NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; small subunit is unidentified
9170	S000000354	ORF	Verified	YBR150C	TBS1	2	544487	541203	C	Probable Zn-finger protein
9172	S000000355	ORF	Verified	YBR151W	APD1	2	545022	545972	W	Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus
9174	S000000356	ORF	Verified	YBR152W	SPP381	2	546370	547245	W	Suppressor of Pre-mRNA Processing mutant; U4/U6.U5-associated snRNP protein; contains a PEST proteolysis motif
9176	S000000357	ORF	Verified	YBR153W	RIB7	2	547454	548188	W	Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway
9178	S000000358	ORF	Verified	YBR154C	RPB5	2	549003	548356	C	RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation
9180	S000000359	ORF	Verified	YBR155W	CNS1	2	549765	550922	W	TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion
9182	S000000360	ORF	Verified	YBR156C	SLI15	2	553194	551098	C	Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase
9184	S000000361	ORF	Verified	YBR157C	ICS2	2	554304	553537	C	Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization
9186	S000000362	ORF	Verified	YBR158W	AMN1	2	556543	558192	W	Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)
9188	S000000363	ORF	Uncharacterized	YBR159W	n.a.	2	558679	559722	W	microsomal beta-keto-reductase
9190	S000000364	ORF	Verified	YBR160W	CDC28	2	560072	560968	W	Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates
9192	S000000365	ORF	Verified	YBR161W	CSH1	2	561629	562759	W	Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p
9194	S000000366	ORF	Uncharacterized	YBR162C	TOS1	2	564565	563198	C	Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C
9196	S000002158	ORF	Verified	YBR162W-A	YSY6	2	565226	565423	W	Protein that participates in secretory pathway
9198	S000000367	ORF	Verified	YBR163W	DEM1	2	565718	567475	W	Protein of unknown function, shows similarity to RNA-processing protein Pta1p
9200	S000000368	ORF	Verified	YBR164C	ARL1	2	568421	567870	C	Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor
9202	S000000369	ORF	Verified	YBR165W	UBS1	2	568847	569680	W	Ubiquitin-conjugating enzyme suppressor that functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity
9204	S000000370	ORF	Verified	YBR166C	TYR1	2	571195	569837	C	Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels
9206	S000000371	ORF	Verified	YBR167C	POP7	2	571885	571463	C	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
9208	S000000372	ORF	Verified	YBR168W	PEX32	2	572366	573607	W	Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p
9210	S000000373	ORF	Verified	YBR169C	SSE2	2	575991	573910	C	Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p
9212	S000000374	ORF	Verified	YBR170C	NPL4	2	578081	576339	C	Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation
9214	S000000375	ORF	Verified	YBR171W	SEC66	2	578359	578979	W	Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER
9216	S000000376	ORF	Verified	YBR172C	SMY2	2	581367	579145	C	Protein of unknown function that interacts with Myo2p; has similarity to S. pombe Mpd2
9218	S000000377	ORF	Verified	YBR173C	UMP1	2	582167	581721	C	Short-lived chaperone required for correct maturation of the 20S proteasome; degraded by proteasome upon completion of its assembly; involved in ubiquitin-mediated proteolysis; mutant defective in degradation of short-lived proteins
9220	S000000379	ORF	Verified	YBR175W	SWD3	2	582403	583350	W	Essential subunit of the COMPASS (Set1C) complex, which methylates Rad6p ubiquitinated histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5
9222	S000000378	ORF	Dubious	YBR174C	n.a.	2	582647	582333	C	Hypothetical protein
9224	S000000380	ORF	Verified	YBR176W	ECM31	2	583715	584653	W	Ketopantoate hydroxymethyltransferase, required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate
9226	S000000382	ORF	Dubious	YBR178W	n.a.	2	586066	586440	W	Hypothetical protein
9228	S000000381	ORF	Verified	YBR177C	EHT1	2	586157	584802	C	Possible serine hydrolase, may be involved in lipid metabolism, null mutant slightly temperature sensitive at 37C
9230	S000000383	ORF	Verified	YBR179C	FZO1	2	589109	586542	C	Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain
9232	S000000384	ORF	Verified	YBR180W	DTR1	2	589736	591454	W	Multidrug resistance dityrosine transporter of the major facilitator superfamily, essential for spore wall synthesis, facilitates the translocation of bisformyl dityrosine through the prospore membrane
9234	S000000385	ORF	Verified	YBR181C	RPS6B	2	592769	591707	C	Protein component of the small (40S) ribosomal subunit; identical to Rps6Ap and has similarity to rat S6 ribosomal protein
9237	S000035076	intron	n.a.	n.a.	n.a.	2	592763	592412	C	n.a.
9238	S000000386	ORF	Verified	YBR182C	SMP1	2	594859	593501	C	Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors
9240	S000028603	ORF	Uncharacterized	YBR182C-A	n.a.	2	595550	595356	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9242	S000000387	ORF	Verified	YBR183W	YPC1	2	596110	597060	W	Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance
9244	S000000388	ORF	Uncharacterized	YBR184W	n.a.	2	597358	598929	W	Hypothetical protein
9246	S000000389	ORF	Verified	YBR185C	MBA1	2	599954	599118	C	Protein involved in assembly of mitochondrial respiratory complexes; may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane
9248	S000000390	ORF	Verified	YBR186W	PCH2	2	600548	602355	W	Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA
9251	S000036995	intron	n.a.	n.a.	n.a.	2	602099	602211	W	n.a.
9252	S000000391	ORF	Uncharacterized	YBR187W	n.a.	2	602629	603471	W	Hypothetical protein
9254	S000000392	ORF	Verified	YBR188C	NTC20	2	604102	603680	C	Member of a complex, including Prp19p, that binds to the spliceosome; required for pre-mRNA splicing
9256	S000000393	ORF	Verified	YBR189W	RPS9B	2	604503	605503	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins
9259	S000037266	intron	n.a.	n.a.	n.a.	2	604510	604922	W	n.a.
9260	S000000394	ORF	Dubious	YBR190W	n.a.	2	605961	606272	W	Protein required for cell viability
9262	S000000395	ORF	Verified	YBR191W	RPL21A	2	606265	607135	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein
9265	S000030994	intron	n.a.	n.a.	n.a.	2	606276	606663	W	n.a.
9266	S000007594	ORF	Dubious	YBR191W-A	n.a.	2	607144	607218	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
9268	S000000396	ORF	Verified	YBR192W	RIM2	2	607647	608780	W	Protein required for respiration, member of the mitochondrial carrier family
9270	S000000397	ORF	Verified	YBR193C	MED8	2	609748	609077	C	Member of RNA Polymerase II transcriptional regulation mediator; Stoichiometric member of mediator complex
9272	S000000398	ORF	Uncharacterized	YBR194W	n.a.	2	610033	610404	W	Protein proposed to be associated with the nuclear pore complex
9274	S000000399	ORF	Verified	YBR195C	MSI1	2	611877	610609	C	Subunit of chromatin assembly factor I (CAF-I), regulates the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46
9276	S000000400	ORF	Verified	YBR196C	PGI1	2	613895	612231	C	Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation
9278	S000028534	ORF	Uncharacterized	YBR196C-A	n.a.	2	614168	614019	C	Identified by fungal homology and RT-PCR
9280	S000028816	ORF	Uncharacterized	YBR196C-B	n.a.	2	614625	614521	C	Identified by expression profiling and mass spectrometry
9282	S000000401	ORF	Uncharacterized	YBR197C	n.a.	2	615851	615198	C	Hypothetical protein
9284	S000000402	ORF	Verified	YBR198C	TAF5	2	618518	616122	C	Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification
9286	S000000403	ORF	Verified	YBR199W	KTR4	2	618904	620298	W	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
9288	S000000404	ORF	Verified	YBR200W	BEM1	2	620867	622522	W	Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p
9290	S000028535	ORF	Uncharacterized	YBR200W-A	n.a.	2	622978	623142	W	Identified by fungal homology and RT-PCR
9292	S000000405	ORF	Verified	YBR201W	DER1	2	623572	624207	W	Endoplasmic reticulum membrane protein, required for ER-associated protein degradation, involved in the retrograde transport of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p
9294	S000000406	ORF	Verified	YBR202W	CDC47	2	625767	628304	W	Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase
9296	S000000407	ORF	Verified	YBR203W	COS111	2	629163	631937	W	Protein required for wild-type resistance to the antifungal drug ciclopirox olamine; not related to the COS family of subtelomerically-encoded proteins
9298	S000000408	ORF	Uncharacterized	YBR204C	n.a.	2	633376	632249	C	Hypothetical protein
9300	S000000409	ORF	Verified	YBR205W	KTR3	2	633617	634831	W	Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
9302	S000000410	ORF	Dubious	YBR206W	n.a.	2	634596	634919	W	Hypothetical protein
9304	S000000411	ORF	Verified	YBR207W	FTH1	2	635141	636538	W	Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis
9306	S000000412	ORF	Verified	YBR208C	DUR1,2	2	642205	636698	C	Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
9308	S000000413	ORF	Dubious	YBR209W	n.a.	2	642578	642895	W	Hypothetical protein
9310	S000006526	tRNA	n.a.	tC(GCA)B	n.a.	2	643073	643002	C	tRNA-Cys
9315	S000006548	tRNA	n.a.	tE(UUC)B	n.a.	2	645162	645233	W	tRNA-Glu
9317	S000000414	ORF	Verified	YBR210W	ERV15	2	645545	645973	W	Protein of unknown function, has similarity to Erv14p
9319	S000000415	ORF	Verified	YBR211C	AME1	2	647127	646153	C	Essential kinetochore protein associated with microtubules and spindle pole bodies, subunit of the COMA complex
9321	S000000416	ORF	Verified	YBR212W	NGR1	2	647881	649899	W	RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase
9323	S000000417	ORF	Verified	YBR213W	MET8	2	650363	651187	W	Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme; also involved in the expression of PAPS reductase and sulfite reductase
9325	S000000418	ORF	Verified	YBR214W	SDS24	2	651410	652993	W	One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC/cyclosome regulation; may play an indirect role in fluid-phase endocytosis
9327	S000000419	ORF	Verified	YBR215W	HPC2	2	653441	655312	W	Highly charged, basic protein required for normal cell-cycle regulation of histone gene transcription; mutants display strong synthetic defects with subunits of FACT, a complex that allows RNA Pol II to elongate through nucleosomes
9329	S000000420	ORF	Verified	YBR216C	YBP1	2	657595	655571	C	Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resulting in the nuclear localization of Yap1p in response to stress
9331	S000000421	ORF	Verified	YBR217W	ATG12	2	657827	658387	W	Protein that becomes conjugated to Atg5p by the E1 enzyme Atg7p, a step that is essential for autophagy
9333	S000000422	ORF	Verified	YBR218C	PYC2	2	662244	658702	C	Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis
9335	S000000423	ORF	Uncharacterized	YBR219C	n.a.	2	663298	662494	C	Hypothetical protein
9338	S000036942	intron	n.a.	n.a.	n.a.	2	662997	662577	C	n.a.
9339	S000000424	ORF	Uncharacterized	YBR220C	n.a.	2	664672	662990	C	Hypothetical protein
9341	S000000425	ORF	Verified	YBR221C	PDB1	2	666248	665148	C	E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria
9343	S000028817	ORF	Uncharacterized	YBR221W-A	n.a.	2	666533	666637	W	Identified by expression profiling and mass spectrometry
9345	S000000426	ORF	Verified	YBR222C	PCS60	2	668346	666715	C	Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase
9347	S000028604	ORF	Dubious	YBR223W-A	n.a.	2	668716	668835	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9349	S000000428	ORF	Dubious	YBR224W	n.a.	2	670120	670635	W	Hypothetical protein
9351	S000000427	ORF	Verified	YBR223C	TDP1	2	670292	668658	C	Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I
9353	S000000429	ORF	Uncharacterized	YBR225W	n.a.	2	670622	673324	W	Hypothetical protein
9355	S000000430	ORF	Dubious	YBR226C	n.a.	2	673560	673150	C	Hypothetical protein
9357	S000000431	ORF	Verified	YBR227C	MCX1	2	675129	673567	C	Mitochondrial ATP-binding protein, possibly a mitochondrial chaperone with non-proteolytic function; similar to bacterial ClpX proteins
9359	S000000432	ORF	Verified	YBR228W	SLX1	2	675308	676222	W	Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p
9361	S000000433	ORF	Verified	YBR229C	ROT2	2	679216	676352	C	Glucosidase II catalytic subunit required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations
9363	S000000434	ORF	Uncharacterized	YBR230C	n.a.	2	680045	679544	C	Hypothetical protein
9366	S000034002	intron	n.a.	n.a.	n.a.	2	680034	679938	C	n.a.
9367	S000029722	ORF	Uncharacterized	YBR230W-A	n.a.	2	680357	680557	W	ORF, Uncharacterized
9369	S000006478	snRNA	n.a.	LSR1	LSR1	2	681853	680679	C	U2 snRNA, component of the spliceosome; functionally and structurally equivalent to mammalian U2, U4, U5, and U6 snRNAs
9371	S000000435	ORF	Uncharacterized	YBR231C	SWC5	2	683085	682174	C	Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin
9373	S000000437	ORF	Verified	YBR233W	PBP2	2	683423	684664	W	RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length
9375	S000000436	ORF	Dubious	YBR232C	n.a.	2	683727	683368	C	Hypothetical protein
9377	S000007595	ORF	Verified	YBR233W-A	DAD3	2	684972	685256	W	Essential protein, component of the DASH complex; involved in spindle integrity and kinetochore function; interacts with Duo1p and Dam1p; localizes to intranuclear spindles and kinetochore
9379	S000000438	ORF	Verified	YBR234C	ARC40	2	686587	685433	C	Essential subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
9381	S000000439	ORF	Uncharacterized	YBR235W	n.a.	2	686896	690258	W	Hypothetical protein
9383	S000000440	ORF	Verified	YBR236C	ABD1	2	691688	690378	C	Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA
9385	S000000441	ORF	Verified	YBR237W	PRP5	2	691964	694513	W	RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA
9387	S000000442	ORF	Uncharacterized	YBR238C	n.a.	2	697297	695102	C	Hypothetical protein
9389	S000000443	ORF	Uncharacterized	YBR239C	n.a.	2	699938	698349	C	Hypothetical protein
9391	S000000444	ORF	Verified	YBR240C	THI2	2	701837	700485	C	Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes
9393	S000000445	ORF	Uncharacterized	YBR241C	n.a.	2	704050	702584	C	Hypothetical protein
9395	S000000446	ORF	Uncharacterized	YBR242W	n.a.	2	704665	705381	W	Hypothetical protein
9397	S000000447	ORF	Verified	YBR243C	ALG7	2	706788	705442	C	UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin
9399	S000000448	ORF	Verified	YBR244W	GPX2	2	707523	708011	W	Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress
9401	S000000449	ORF	Verified	YBR245C	ISW1	2	711534	708145	C	Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation
9403	S000000450	ORF	Uncharacterized	YBR246W	n.a.	2	711586	712749	W	Hypothetical protein
9405	S000000451	ORF	Verified	YBR247C	ENP1	2	714450	712999	C	Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus
9407	S000000452	ORF	Verified	YBR248C	HIS7	2	716460	714802	C	Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor
9409	S000000453	ORF	Verified	YBR249C	ARO4	2	717989	716877	C	3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine
9411	S000000454	ORF	Uncharacterized	YBR250W	n.a.	2	719028	720599	W	Hypothetical protein
9413	S000000455	ORF	Verified	YBR251W	MRPS5	2	721385	722308	W	Mitochondrial ribosomal protein of the small subunit
9415	S000000456	ORF	Verified	YBR252W	DUT1	2	722606	723049	W	dUTPase, catalyzes the hydrolysis of dUTP to dUMP and PPi and thereby prevents the incorporation of uracil into DNA during replication
9417	S000000457	ORF	Verified	YBR253W	SRB6	2	723265	723630	W	Protein involved in transcription as part of the Srb/Mediator complex
9419	S000000458	ORF	Verified	YBR254C	TRS20	2	724258	723731	C	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder
9421	S000000459	ORF	Uncharacterized	YBR255W	n.a.	2	724451	726535	W	Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
9423	S000007649	ORF	Uncharacterized	YBR255C-A	n.a.	2	727069	726613	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
9426	S000037336	intron	n.a.	n.a.	n.a.	2	727006	726913	C	n.a.
9427	S000000460	ORF	Verified	YBR256C	RIB5	2	728097	727381	C	Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway
9429	S000000461	ORF	Verified	YBR257W	POP4	2	728880	729719	W	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P
9431	S000000462	ORF	Verified	YBR258C	SHG1	2	730157	729729	C	Subunit of the COMPASS (Set1C) complex, which methylates Rad6p ubiquitinated histone H3 on lysine 4 and is required in transcriptional silencing near telomeres
9433	S000000463	ORF	Uncharacterized	YBR259W	n.a.	2	730382	732448	W	Hypothetical protein
9435	S000000464	ORF	Verified	YBR260C	RGD1	2	734634	732634	C	GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization
9437	S000000465	ORF	Uncharacterized	YBR261C	n.a.	2	735525	734827	C	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
9439	S000000466	ORF	Uncharacterized	YBR262C	n.a.	2	736035	735715	C	The authentic, non-tagged protein was localized to the mitochondria
9441	S000000467	ORF	Verified	YBR263W	SHM1	2	736259	737731	W	Serine hydroxymethyltransferase, mitochondrial
9443	S000000468	ORF	Verified	YBR264C	YPT10	2	738364	737765	C	GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles
9445	S000000469	ORF	Verified	YBR265W	TSC10	2	738577	739539	W	3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family
9447	S000000471	ORF	Verified	YBR267W	REI1	2	739836	741017	W	Protein of unknown function involved in bud growth in the mitotic signaling network; proposed negative regulator of Swe1p and Gin4p; contains dispersed C2H2 zinc finger domains
9449	S000000470	ORF	Dubious	YBR266C	SLM6	2	740383	739931	C	Protein with a potential role in actin cytoskeleton organization; gene exhibits synthetic genetic interaction with MSS4 encoding phosphatidylinositol 4-phosphate kinase
9451	S000000472	ORF	Verified	YBR268W	MRPL37	2	741294	741611	W	Mitochondrial ribosomal protein of the large subunit
9453	S000000473	ORF	Uncharacterized	YBR269C	n.a.	2	742571	742155	C	The authentic, non-tagged protein was localized to the mitochondria
9455	S000000474	ORF	Uncharacterized	YBR270C	n.a.	2	744393	742756	C	Hypothetical protein
9457	S000000475	ORF	Uncharacterized	YBR271W	n.a.	2	744847	746106	W	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
9459	S000000476	ORF	Verified	YBR272C	HSM3	2	747798	746356	C	Protein of unknown function, involved in DNA mismatch repair during slow growth; has weak similarity to Msh1p
9461	S000000477	ORF	Uncharacterized	YBR273C	UBX7	2	749366	748056	C	UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
9463	S000000478	ORF	Verified	YBR274W	CHK1	2	749589	751172	W	checkpoint kinase 1; homolog of the S. pombe and mammalian Chk1 checkpoint kinases; Protein kinase Chk1
9465	S000000479	ORF	Verified	YBR275C	RIF1	2	757101	751351	C	Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation
9467	S000000480	ORF	Verified	YBR276C	PPS1	2	760039	757616	C	Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle
9469	S000000482	ORF	Verified	YBR278W	DPB3	2	760290	760895	W	Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle
9471	S000000481	ORF	Dubious	YBR277C	n.a.	2	760612	760211	C	Hypothetical protein
9473	S000000483	ORF	Verified	YBR279W	PAF1	2	761253	762590	W	RNA polymerase II-associated protein, defines a large complex that is biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme and is required for full expression of a subset of cell cycle-regulated genes
9475	S000000484	ORF	Uncharacterized	YBR280C	n.a.	2	764693	762780	C	Hypothetical protein
9477	S000000485	ORF	Uncharacterized	YBR281C	n.a.	2	767602	764966	C	Hypothetical protein
9479	S000000486	ORF	Verified	YBR282W	MRPL27	2	768236	768676	W	Mitochondrial ribosomal protein of the large subunit
9481	S000000487	ORF	Verified	YBR283C	SSH1	2	770411	768939	C	Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential
9483	S000000488	ORF	Uncharacterized	YBR284W	n.a.	2	771235	773628	W	Hypothetical protein
9485	S000000489	ORF	Uncharacterized	YBR285W	n.a.	2	773918	774352	W	Hypothetical protein
9487	S000000490	ORF	Verified	YBR286W	APE3	2	774618	776309	W	Vacuolar aminopeptidase Y, processed to mature form by Prb1p
9489	S000000491	ORF	Uncharacterized	YBR287W	n.a.	2	776567	777850	W	Protein of unknown function; mutation results in a zinc sensitive phenotype
9491	S000000492	ORF	Verified	YBR288C	APM3	2	779459	778008	C	Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway
9493	S000000493	ORF	Verified	YBR289W	SNF5	2	779663	782380	W	One of 11 subunits of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p
9495	S000000494	ORF	Verified	YBR290W	BSD2	2	782587	783552	W	Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification
9497	S000000495	ORF	Verified	YBR291C	CTP1	2	784568	783669	C	Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family
9499	S000000496	ORF	Dubious	YBR292C	n.a.	2	785069	784698	C	Hypothetical protein
9501	S000000497	ORF	Verified	YBR293W	VBA2	2	787001	788425	W	Permease of basic amino acids in the vacuolar membrane
9503	S000000498	ORF	Verified	YBR294W	SUL1	2	789230	791809	W	High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates
9505	S000000499	ORF	Verified	YBR295W	PCA1	2	792843	796493	W	P-type metal-transporting ATPase with a role in copper and iron homeostasis; R970G-substitution in the C-terminal region confers cadmium resistance
9507	S000000500	ORF	Verified	YBR296C	PHO89	2	798516	796792	C	Na+/Pi cotransporter, active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p
9509	S000028605	ORF	Uncharacterized	YBR296C-A	n.a.	2	800236	800117	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9511	S000000501	ORF	Verified	YBR297W	MAL33	2	800517	801923	W	MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C
9513	S000000502	ORF	Verified	YBR298C	MAL31	2	804469	802625	C	Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C
9515	S000028606	ORF	Uncharacterized	YBR298C-A	n.a.	2	805250	805029	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9517	S000000503	ORF	Verified	YBR299W	MAL32	2	805345	807099	W	Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C
9519	S000000505	ORF	Verified	YBR301W	DAN3	2	809051	809413	W	Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth
9521	S000000504	ORF	Dubious	YBR300C	n.a.	2	809091	808594	C	Hypothetical protein
9523	S000000506	ORF	Verified	YBR302C	COS2	2	811473	810334	C	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
9541	S000000581	ORF	Dubious	YCL076W	n.a.	3	1392	2135	W	Hypothetical protein
9548	S000000575	ORF	Uncharacterized	YCL073C	n.a.	3	8326	6479	C	Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YKR106W
9550	S000000574	ORF	Verified	YCL069W	VBA3	3	9706	11082	W	Permease of basic amino acids in the vacuolar membrane
9554	S000000573	ORF	Uncharacterized	YCL068C	n.a.	3	12285	11503	C	Hypothetical protein
9556	S000000572	ORF	Verified	YCL067C	HMLALPHA2	3	13018	12386	C	Silenced copy of ALPHA2, encoding a homeobox-domain containing protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with A1p in diploid cells to repress haploid-specific gene expression
9558	S000000571	ORF	Verified	YCL066W	HMLALPHA1	3	13282	13809	W	Silenced copy of ALPHA1, encoding a transcriptional coactivator involved in the regulation of mating-type alpha-specific gene expression
9560	S000000570	ORF	Dubious	YCL065W	n.a.	3	13751	14119	W	Hypothetical protein
9568	S000000569	ORF	Verified	YCL064C	CHA1	3	16880	15798	C	catabolism of hydroxy amino acids; catabolic serine (threonine) dehydratase
9570	S000000568	ORF	Verified	YCL063W	VAC17	3	17290	18561	W	Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p
9572	S000000566	ORF	Verified	YCL061C	MRC1	3	22106	18816	C	S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p; protein involved in replication checkpoint
9574	S000000564	ORF	Verified	YCL059C	KRR1	3	23379	22429	C	Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit
9576	S000028518	ORF	Uncharacterized	YCL058W-A	n.a.	3	23527	23925	W	Identified by homology to <i>Ashbya gossypii</i>
9578	S000000563	ORF	Dubious	YCL058C	FYV5	3	23981	23523	C	Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in ion homeostasis
9580	S000007547	ORF	Uncharacterized	YCL057C-A	n.a.	3	24325	24032	C	Hypothetical protein, has similarity to proteins in S. pombe, C. elegans, D. melanogaster.
9582	S000000562	ORF	Verified	YCL057W	PRD1	3	24768	26906	W	Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins
9584	S000000561	ORF	Uncharacterized	YCL056C	n.a.	3	27359	26925	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
9586	S000000560	ORF	Verified	YCL055W	KAR4	3	27929	28936	W	Transcription factor required for induction of KAR3 and CIK1 during mating, also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone
9590	S000000559	ORF	Verified	YCL054W	SPB1	3	31449	33974	W	AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the putative tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants
9592	S000000557	ORF	Verified	YCL052C	PBN1	3	35393	34143	C	Essential component of glycosylphosphatidylinositol-mannosyltransferase I, required for the autocatalytic post-translational processing of the protease B precursor Prb1p, localizes to ER in lumenal orientation; homolog of mammalian PIG-X
9594	S000000556	ORF	Verified	YCL051W	LRE1	3	35865	37616	W	Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes
9596	S000000555	ORF	Verified	YCL050C	APA1	3	38801	37836	C	Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p
9600	S000000554	ORF	Uncharacterized	YCL049C	n.a.	3	40724	39786	C	Hypothetical protein
9602	S000000553	ORF	Verified	YCL048W	SPS22	3	42165	43556	W	Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall
9604	S000000552	ORF	Uncharacterized	YCL047C	n.a.	3	44437	43661	C	Hypothetical protein
9606	S000000551	ORF	Dubious	YCL046W	n.a.	3	46640	46963	W	Hypothetical protein
9608	S000000550	ORF	Uncharacterized	YCL045C	n.a.	3	46905	44623	C	Hypothetical protein
9610	S000000549	ORF	Uncharacterized	YCL044C	n.a.	3	48364	47111	C	Hypothetical protein
9612	S000000548	ORF	Verified	YCL043C	PDI1	3	50221	48653	C	Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds
9614	S000000547	ORF	Uncharacterized	YCL042W	n.a.	3	50584	50943	W	Hypothetical protein
9616	S000000546	ORF	Dubious	YCL041C	n.a.	3	50627	50133	C	Protein required for cell viability
9618	S000000545	ORF	Verified	YCL040W	GLK1	3	50838	52340	W	Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources
9620	S000000544	ORF	Verified	YCL039W	GID7	3	52645	54882	W	Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions
9622	S000000543	ORF	Verified	YCL038C	ATG22	3	56527	54941	C	Protein required for the breakdown of autophagic vesicles in the vacuole during autophagy, putative integral membrane protein that localizes to vacuolar membranes and punctate structures attached to the vacuole
9624	S000000542	ORF	Verified	YCL037C	SRO9	3	58678	57374	C	Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif
9626	S000000541	ORF	Uncharacterized	YCL036W	GFD2	3	59026	60726	W	Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation
9628	S000000540	ORF	Verified	YCL035C	GRX1	3	61173	60841	C	Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair; protects cells from oxidative damage
9630	S000000539	ORF	Verified	YCL034W	LSB5	3	61658	62722	W	Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
9632	S000000538	ORF	Uncharacterized	YCL033C	n.a.	3	63282	62776	C	Hypothetical protein
9634	S000000537	ORF	Verified	YCL032W	STE50	3	63441	64481	W	Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction
9636	S000000536	ORF	Verified	YCL031C	RRP7	3	65568	64675	C	Essential protein involved in rRNA processing and ribosome biogenesis
9638	S000000535	ORF	Verified	YCL030C	HIS4	3	68333	65934	C	Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis
9640	S000000534	ORF	Verified	YCL029C	BIK1	3	69921	68599	C	Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170
9642	S000000533	ORF	Verified	YCL028W	RNQ1	3	70150	71367	W	[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate
9644	S000000532	ORF	Verified	YCL027W	FUS1	3	71803	73341	W	Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate
9646	S000007548	ORF	Uncharacterized	YCL026C-B	n.a.	3	73986	73405	C	Hypothetical protein
9650	S000000589	ORF	Verified	YCL026C-A	FRM2	3	75285	74704	C	Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis
9652	S000000530	ORF	Verified	YCL025C	AGP1	3	77918	76131	C	Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)
9654	S000000529	ORF	Verified	YCL024W	KCC4	3	79161	82274	W	Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p
9656	S000000528	ORF	Dubious	YCL023C	n.a.	3	79295	78948	C	Hypothetical protein
9658	S000000527	ORF	Dubious	YCL022C	n.a.	3	82084	81569	C	Hypothetical protein
9660	S000006549	tRNA	n.a.	tE(UUC)C	n.a.	3	82532	82461	C	tRNA-Glu
9663	S000007549	ORF	Uncharacterized	YCL021W-A	n.a.	3	83619	83996	W	Hypothetical protein
9677	S000006637	tRNA	n.a.	tL(CAA)C	SUP53	3	90858	90971	W	tRNA-Leu
9678	S000033768	intron	n.a.	n.a.	n.a.	3	90896	90927	W	n.a.
9681	S000000523	ORF	Verified	YCL018W	LEU2	3	91323	92417	W	Beta-isopropylmalate dehydrogenase, catalyzes the third step in the leucine biosynthesis pathway
9683	S000000522	ORF	Verified	YCL017C	NFS1	3	94269	92776	C	Cysteine desulfurase involved in iron-sulfur cluster (Fe/S)biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria
9685	S000000521	ORF	Verified	YCL016C	DCC1	3	95762	94620	C	Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion
9687	S000000520	ORF	Verified	YCL014W	BUD3	3	96280	101190	W	Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding
9689	S000029705	ORF	Verified	YCL012C	n.a.	3	101787	101316	C	Nonessential protein of unknown function; orthologs are present in S. bayanus, S. paradoxus and Ashbya gossypii.
9692	S000036815	intron	n.a.	n.a.	n.a.	3	101699	101633	C	n.a.
9693	S000000517	ORF	Verified	YCL011C	GBP2	3	103357	102074	C	Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro
9695	S000000516	ORF	Verified	YCL010C	SGF29	3	104349	103570	C	SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex
9697	S000000515	ORF	Verified	YCL009C	ILV6	3	105547	104618	C	Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria
9699	S000000514	ORF	Verified	YCL008C	STP22	3	106852	105695	C	Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype
9701	S000028508	ORF	Verified	YCL005W-A	VMA9	3	107022	107416	W	Vacuolar H+ ATPase subunit e of the V0 (membrane) sector, essential for vacuolar acidification
9705	S000030221	intron	n.a.	n.a.	n.a.	3	107033	107109	W	n.a.
9706	S000030222	intron	n.a.	n.a.	n.a.	3	107191	107286	W	n.a.
9707	S000000513	ORF	Dubious	YCL007C	n.a.	3	107365	106973	C	Dubious open reading frame that overlaps YCL005W-A (87%); mutations in YCL007C were thought to confer sensitivity to calcofluor white, but this phenotype was later shown to be due to the defect in YCL005W-A
9709	S000006503	snoRNA	n.a.	snR43	SNR43	3	107711	107503	C	H/ACA small nucleolar RNA (snoRNA); predicted to guide pseudouridylation of large subunit rRNA at position 965
9711	S000000511	ORF	Uncharacterized	YCL005W	n.a.	3	108020	108790	W	Hypothetical protein
9715	S000000510	ORF	Verified	YCL004W	PGS1	3	109104	110669	W	Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis
9717	S000000508	ORF	Uncharacterized	YCL002C	n.a.	3	111673	110842	C	Hypothetical protein
9720	S000037736	intron	n.a.	n.a.	n.a.	3	111631	111556	C	n.a.
9721	S000000507	ORF	Verified	YCL001W	RER1	3	111913	112479	W	Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER
9723	S000007221	ORF	Uncharacterized	YCL001W-A	n.a.	3	113077	113538	W	Hypothetical protein
9725	S000007596	ORF	Uncharacterized	YCL001W-B	n.a.	3	113767	114021	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
9732	S000000594	ORF	Dubious	YCR001W	n.a.	3	115682	115996	W	Hypothetical protein
9734	S000000595	ORF	Verified	YCR002C	CDC10	3	118345	117377	C	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
9736	S000000596	ORF	Verified	YCR003W	MRPL32	3	118617	119168	W	Mitochondrial ribosomal protein of the large subunit
9738	S000000597	ORF	Verified	YCR004C	YCP4	3	120315	119572	C	Protein of unknown function, has sequence and structural similarity to flavodoxins; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
9740	S000000598	ORF	Verified	YCR005C	CIT2	3	122325	120943	C	Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors
9742	S000000599	ORF	Dubious	YCR006C	n.a.	3	123000	122527	C	Hypothetical protein
9744	S000006678	tRNA	n.a.	tP(AGG)C	SUF2	3	123645	123574	C	tRNA-Pro
9747	S000000600	ORF	Uncharacterized	YCR007C	n.a.	3	126727	126008	C	Putative integral membrane protein, member of DUP240 gene family
9749	S000006668	tRNA	n.a.	tN(GUU)C	n.a.	3	127713	127786	W	tRNA-Asn
9751	S000000601	ORF	Verified	YCR008W	SAT4	3	128467	130278	W	Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p
9753	S000000602	ORF	Verified	YCR009C	RVS161	3	131539	130742	C	Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress
9757	S000000603	ORF	Verified	YCR010C	ADY2	3	133121	132270	C	Acetate transporter required for normal sporulation
9759	S000000604	ORF	Verified	YCR011C	ADP1	3	136870	133721	C	Putative ATP-dependent permease of the ABC transporter family of proteins
9761	S000000605	ORF	Verified	YCR012W	PGK1	3	137743	138993	W	3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis
9763	S000000606	ORF	Dubious	YCR013C	n.a.	3	139046	138399	C	Protein required for cell viability
9765	S000000607	ORF	Verified	YCR014C	POL4	3	140930	139182	C	DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta
9767	S000000608	ORF	Uncharacterized	YCR015C	n.a.	3	142167	141214	C	Hypothetical protein
9769	S000007298	snoRNA	n.a.	snR33	SNR33	3	142543	142361	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 1041
9772	S000006575	tRNA	n.a.	tG(GCC)C	SUF16	3	142768	142698	C	tRNA-Gly
9774	S000000609	ORF	Uncharacterized	YCR016W	n.a.	3	143631	144503	W	Hypothetical protein
9776	S000000610	ORF	Verified	YCR017C	CWH43	3	147631	144770	C	Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion
9778	S000000611	ORF	Verified	YCR018C	SRD1	3	148900	148235	C	Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation
9781	S000006658	tRNA	n.a.	tM(CAU)C	n.a.	3	149917	149988	W	tRNA-Met
9785	S000006615	tRNA	n.a.	tK(CUU)C	n.a.	3	151353	151281	C	tRNA-Lys
9788	S000007230	ORF	Dubious	YCR018C-A	n.a.	3	151859	151605	C	Similar to probable membrane protein YLR334C and ORF YOL106W
9790	S000000612	ORF	Verified	YCR019W	MAK32	3	152834	153925	W	Protein necessary for structural stability of L-A double-stranded RNA-containing particles
9792	S000000613	ORF	Verified	YCR020C	PET18	3	154656	154009	C	Protein required for respiratory growth and stability of the mitochondrial genome
9794	S000000614	ORF	Verified	YCR020C-A	MAK31	3	155093	154827	C	Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family
9796	S000006439	ORF	Verified	YCR020W-B	HTL1	3	155317	155553	W	Subunit of the RSC chromatin remodeling complex, a multisubunit complex that functions in transcriptional regulation, chromosome stability and establishing sister chromatid cohesion
9798	S000000615	ORF	Verified	YCR021C	HSP30	3	157102	156104	C	Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase
9800	S000000616	ORF	Dubious	YCR022C	n.a.	3	157760	157416	C	Hypothetical protein
9802	S000000617	ORF	Uncharacterized	YCR023C	n.a.	3	160368	158533	C	Hypothetical protein
9804	S000000618	ORF	Verified	YCR024C	SLM5	3	162217	160739	C	Mitochondrial asparaginyl-tRNA synthetase
9806	S000028818	ORF	Uncharacterized	YCR024C-B	n.a.	3	162860	162594	C	Identified by expression profiling and mass spectrometry
9808	S000000619	ORF	Verified	YCR024C-A	PMP1	3	163062	162940	C	May regulate plasma membrane H(+)-ATPase; Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p)
9810	S000000620	ORF	Dubious	YCR025C	n.a.	3	163851	163441	C	Hypothetical protein
9812	S000000621	ORF	Uncharacterized	YCR026C	n.a.	3	166334	164106	C	Hypothetical protein
9818	S000000622	ORF	Verified	YCR027C	RHB1	3	167994	167365	C	Putative Rheb-related GTPase involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins
9820	S000006692	tRNA	n.a.	tQ(UUG)C	n.a.	3	168367	168296	C	tRNA-Gln
9823	S000000623	ORF	Verified	YCR028C	FEN2	3	172419	170881	C	Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph
9825	S000007222	ORF	Verified	YCR028C-A	RIM1	3	173435	172945	C	Single-stranded DNA-binding protein that is essential for mitochondrial genome maintenance; Single-stranded zinc finger DNA-binding protein
9828	S000030989	intron	n.a.	n.a.	n.a.	3	173193	173111	C	n.a.
9829	S000000626	ORF	Verified	YCR030C	SYP1	3	176433	173821	C	Protein with a potential role in actin cytoskeletal organization; overexpression suppresses a pfy1 (profilin) null mutation
9831	S000006456	snoRNA	n.a.	snR65	SNR65	3	177178	177277	W	guides 2'-O-methylation on large subunit rRNA at U2345; small nucleolar RNA snR65
9833	S000000627	ORF	Verified	YCR031C	RPS14A	3	178215	177495	C	Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins
9836	S000037574	intron	n.a.	n.a.	n.a.	3	178208	177902	C	n.a.
9837	S000007314	snoRNA	n.a.	snR189	SNR189	3	178793	178605	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of small subunit rRNA at position 466 and of large subunit rRNA at position 2730
9839	S000000628	ORF	Verified	YCR032W	BPH1	3	179515	186018	W	Protein homologous to human Chediak-Higashi syndrome protein and murine beige gene, which are implicated in disease syndromes due to defective lysosomal trafficking
9841	S000000629	ORF	Verified	YCR033W	SNT1	3	186484	190164	W	Subunit of the Set3C deacetylase complex; putative DNA-binding protein
9843	S000000630	ORF	Verified	YCR034W	FEN1	3	190587	191630	W	Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway
9845	S000000631	ORF	Verified	YCR035C	RRP43	3	193013	191829	C	Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp4p and Dis3p; required for efficient maturation of 5.8S, 18S and 25S rRNA
9847	S000000632	ORF	Verified	YCR036W	RBK1	3	193292	194293	W	Putative ribokinase
9851	S000000633	ORF	Verified	YCR037C	PHO87	3	197180	194409	C	Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments
9853	S000007597	ORF	Dubious	YCR038W-A	n.a.	3	199288	199413	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
9855	S000000634	ORF	Verified	YCR038C	BUD5	3	199544	197616	C	GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types
9857	S000000635	ORF	Verified	YCR039C	MATALPHA2	3	200173	199541	C	Homeobox-domain containing protein which acts with Mcm1p in haploid cells to repress a-specific genes; in diploid cells Alpha2p acts together with A1p to repress transcription of haploid-specific genes
9859	S000000636	ORF	Verified	YCR040W	MATALPHA1	3	200437	200964	W	Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the alpha mating type cassette
9861	S000000637	ORF	Dubious	YCR041W	n.a.	3	200906	201238	W	Hypothetical protein
9863	S000000638	ORF	Verified	YCR042C	TAF2	3	205392	201169	C	TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation
9865	S000000639	ORF	Uncharacterized	YCR043C	n.a.	3	206639	206256	C	Hypothetical protein
9867	S000000640	ORF	Verified	YCR044C	PER1	3	207945	206872	C	Vacuolar membrane protein that seems to be involved in Mn2+ homeostasis; mutant is dependent on activation of the unfolded protein response pathway for viability
9869	S000028607	ORF	Dubious	YCR045W-A	n.a.	3	208746	209096	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9871	S000000641	ORF	Uncharacterized	YCR045C	n.a.	3	209605	208130	C	Hypothetical protein
9873	S000000642	ORF	Verified	YCR046C	IMG1	3	210418	209909	C	Mitochondrial ribosomal protein of the small subunit, required for respiration and for maintenance of the mitochondrial genome
9875	S000028608	ORF	Dubious	YCR047W-A	n.a.	3	211296	211502	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9877	S000000643	ORF	Verified	YCR047C	BUD23	3	211540	210713	C	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
9879	S000000644	ORF	Verified	YCR048W	ARE1	3	211924	213756	W	Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen
9881	S000000645	ORF	Dubious	YCR049C	n.a.	3	212312	211866	C	Hypothetical protein
9883	S000000646	ORF	Dubious	YCR050C	n.a.	3	213767	213459	C	Hypothetical protein
9885	S000000647	ORF	Uncharacterized	YCR051W	n.a.	3	214066	214734	W	Hypothetical protein
9887	S000000648	ORF	Verified	YCR052W	RSC6	3	214989	216440	W	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential for mitotic growth; homolog of SWI/SNF subunit Swp73p
9889	S000000649	ORF	Verified	YCR053W	THR4	3	216692	218236	W	Threonine synthase, conserved protein that catalyzes formation of threonine from 0-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway
9891	S000000650	ORF	Verified	YCR054C	CTR86	3	220062	218371	C	Essential protein of unknown function
9893	S000000653	ORF	Verified	YCR057C	PWP2	3	223223	220452	C	Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis
9895	S000000655	ORF	Verified	YCR059C	YIH1	3	224225	223449	C	piecemeal microautophagy of the nucleus (PMN)
9897	S000000656	ORF	Verified	YCR060W	TAH1	3	224394	224729	W	HSP90 cofactor; interacts with Hsp82p, Pih1p, Rvb1 and Rvb2, contains a single TPR domain with at least two TPR motifs
9900	S000000657	ORF	Uncharacterized	YCR061W	n.a.	3	225558	227453	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
9902	S000006730	tRNA	n.a.	tS(CGA)C	SUP61	3	227937	228037	W	tRNA-Ser
9903	S000029830	intron	n.a.	n.a.	n.a.	3	227974	227992	W	n.a.
9906	S000000659	ORF	Verified	YCR063W	BUD31	3	228313	228786	W	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
9908	S000000660	ORF	Dubious	YCR064C	n.a.	3	228500	228090	C	Hypothetical protein
9910	S000000661	ORF	Verified	YCR065W	HCM1	3	229305	230999	W	Forkhead transcription factor involved in cell cycle specific transcription of SPC110, encoding a spindle pole body (SPB) calmodulin binding protein; dosage-dependent suppressor of calmodulin mutants with specific defects in SPB assembly
9912	S000000662	ORF	Verified	YCR066W	RAD18	3	231495	232958	W	Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif
9914	S000000663	ORF	Verified	YCR067C	SED4	3	236317	233120	C	Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p
9916	S000000664	ORF	Verified	YCR068W	ATG15	3	237209	238771	W	Lipase, required for intravacuolar lysis of autophagic bodies; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway
9918	S000000665	ORF	Verified	YCR069W	CPR4	3	239050	240006	W	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway
9920	S000000667	ORF	Verified	YCR071C	IMG2	3	240538	240098	C	Mitochondrial ribosomal protein of the small subunit
9922	S000000668	ORF	Uncharacterized	YCR072C	n.a.	3	242347	240800	C	Protein required for cell viability
9924	S000000669	ORF	Verified	YCR073C	SSK22	3	246579	242584	C	MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; functionally redundant with, and homologous to, Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p
9926	S000000718	ORF	Verified	YCR073W-A	SOL2	3	246959	247906	W	Protein with a possible role in tRNA export; shows similarity to glucose-6-phosphate dehydrogenase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol1p, Sol3p, and Sol4p
9928	S000000671	ORF	Verified	YCR075C	ERS1	3	248811	248029	C	Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains
9930	S000028519	ORF	Uncharacterized	YCR075W-A	n.a.	3	248971	249198	W	Identified by homology to <i>Ashbya gossypii</i>
9932	S000000672	ORF	Uncharacterized	YCR076C	n.a.	3	250041	249289	C	Hypothetical protein
9934	S000000673	ORF	Verified	YCR077C	PAT1	3	252624	250234	C	Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p
9936	S000002133	ORF	Uncharacterized	YCR079W	n.a.	3	252841	254169	W	Hypothetical protein
9938	S000000677	ORF	Verified	YCR081W	SRB8	3	254367	258650	W	RNA polymerase II mediator complex subunit
9940	S000028609	ORF	Dubious	YCR081C-A	n.a.	3	258647	258411	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
9942	S000000678	ORF	Uncharacterized	YCR082W	n.a.	3	258879	259265	W	Protein of unknown function, proposed to be a Ada Histone acetyltransferase complex component; GFP tagged protein is localized to the cytoplasm and nucleus
9944	S000000679	ORF	Verified	YCR083W	TRX3	3	259574	259957	W	Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p
9946	S000000680	ORF	Verified	YCR084C	TUP1	3	262448	260307	C	General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes
9948	S000000681	ORF	Dubious	YCR085W	n.a.	3	262912	263265	W	Hypothetical protein
9950	S000000682	ORF	Verified	YCR086W	CSM1	3	263388	263960	W	Protein that forms a complex with Lrs4p, located in the nucleolus; Lrs4p-Csm1p heterodimer binds to Mam1p at kinetochores during meiosis I to mediate accurate chromosome segregation, may be involved in premeiotic DNA replication
9952	S000000683	ORF	Dubious	YCR087W	n.a.	3	263972	264487	W	Hypothetical protein
9954	S000007223	ORF	Uncharacterized	YCR087C-A	n.a.	3	264463	264002	C	Hypothetical protein
9956	S000000684	ORF	Verified	YCR088W	ABP1	3	265064	266842	W	Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization
9958	S000000685	ORF	Verified	YCR089W	FIG2	3	267430	272259	W	Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating
9961	S000000686	ORF	Uncharacterized	YCR090C	n.a.	3	272859	272311	C	Hypothetical protein
9963	S000000687	ORF	Verified	YCR091W	KIN82	3	274400	276562	W	Putative serine/threonine protein kinase, most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily
9965	S000000688	ORF	Verified	YCR092C	MSH3	3	279903	276760	C	Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability
9967	S000000689	ORF	Verified	YCR093W	CDC39	3	280113	286439	W	Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
9969	S000000690	ORF	Verified	YCR094W	CDC50	3	286758	287933	W	Endosomal protein that regulates cell polarity; similar to Ynr048wp and Lem3p
9971	S000000691	ORF	Uncharacterized	YCR095C	n.a.	3	289254	288166	C	Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
9973	S000029724	ORF	Uncharacterized	YCR095W-A	n.a.	3	289635	289793	W	ORF, Uncharacterized
9978	S000000692	ORF	Verified	YCR096C	HMRA2	3	293534	293175	C	Silenced copy of A2, encoding a protein of with similarity to Alpha2p that is required along with A1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system
9980	S000000694	ORF	Verified	YCR097W	HMRA1	3	293831	294317	W	Silenced copy of A1, encoding a homeobox-domain containing corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells
9984	S000030024	intron	n.a.	n.a.	n.a.	3	293936	293989	W	n.a.
9985	S000030025	intron	n.a.	n.a.	n.a.	3	294236	294287	W	n.a.
9988	S000007632	ORF	Dubious	YCR097W-A	n.a.	3	294435	294701	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36. (ChrIII)
9991	S000006738	tRNA	n.a.	tT(AGU)C	n.a.	3	295480	295552	W	tRNA-Thr
9994	S000000695	ORF	Verified	YCR098C	GIT1	3	298601	297045	C	Plasma membrane permease, mediates uptake of the phosphatidylinositol metabolite glycerophosphoinositol as a source of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability
9996	S000000696	ORF	Uncharacterized	YCR099C	n.a.	3	301295	300828	C	Hypothetical protein
9998	S000000697	ORF	Uncharacterized	YCR100C	n.a.	3	302217	301267	C	Hypothetical protein
10000	S000000698	ORF	Uncharacterized	YCR101C	n.a.	3	303026	302478	C	Hypothetical protein
10002	S000000699	ORF	Uncharacterized	YCR102C	n.a.	3	305463	304357	C	Hypothetical protein
10004	S000007231	ORF	Dubious	YCR102W-A	n.a.	3	306731	306928	W	Similar to several yeast probable membrane proteins, including YNR075W and YFL062W
10006	S000000701	ORF	Verified	YCR104W	PAU3	3	307797	308171	W	Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
10008	S000000702	ORF	Verified	YCR105W	ADH7	3	309066	310151	W	NADPH-dependent cinnamyl alcohol dehydrogenase family member with broad substrate specificity; may be involved in fusel alcohol synthesis
10010	S000000703	ORF	Verified	YCR106W	RDS1	3	310954	313452	W	Zinc cluster protein involved in conferring resistance to cycloheximide
10012	S000000704	ORF	Verified	YCR107W	AAD3	3	313886	314977	W	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
10020	S000028536	ORF	Uncharacterized	YCR108C	n.a.	3	316184	315993	C	Identified by fungal homology and RT-PCR
10030	S000002407	ORF	Verified	YDL248W	COS7	4	1802	2953	W	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
10032	S000007602	ORF	Dubious	YDL247W-A	n.a.	4	3762	3836	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
10034	S000002406	ORF	Verified	YDL247W	MPH2	4	5985	7814	W	Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph3p; encoded in a subtelomeric position in a region likely to have undergone duplication
10036	S000002405	ORF	Uncharacterized	YDL246C	SOR2	4	9756	8683	C	Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in fructose or mannose metabolism
10038	S000002404	ORF	Verified	YDL245C	HXT15	4	13360	11657	C	Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
10040	S000002403	ORF	Verified	YDL244W	THI13	4	16204	17226	W	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
10042	S000002402	ORF	Verified	YDL243C	AAD4	4	18566	17577	C	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response
10044	S000002401	ORF	Dubious	YDL242W	n.a.	4	18959	19312	W	Hypothetical protein
10046	S000002400	ORF	Uncharacterized	YDL241W	n.a.	4	20635	21006	W	Hypothetical protein
10048	S000007601	ORF	Dubious	YDL240C-A	n.a.	4	22608	22471	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
10050	S000002399	ORF	Verified	YDL240W	LRG1	4	22823	25876	W	Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis
10052	S000002398	ORF	Verified	YDL239C	ADY3	4	28775	26403	C	Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p
10054	S000002397	ORF	Verified	YDL238C	GUD1	4	30454	28985	C	Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures
10056	S000002396	ORF	Uncharacterized	YDL237W	n.a.	4	30657	31829	W	Hypothetical protein
10058	S000002395	ORF	Verified	YDL236W	PHO13	4	32296	33234	W	Alkaline phosphatase specific for p-nitrophenyl phosphate, involved in dephosphorylation of histone II-A and casein
10060	S000002394	ORF	Verified	YDL235C	YPD1	4	33918	33415	C	Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus
10062	S000002393	ORF	Verified	YDL234C	GYP7	4	36478	34238	C	GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking
10064	S000002392	ORF	Uncharacterized	YDL233W	n.a.	4	36798	38174	W	Hypothetical protein
10066	S000002391	ORF	Verified	YDL232W	OST4	4	38488	38598	W	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; type I membrane protein of 36 residues that binds Stt3p and Ost3p together in a subcomplex
10068	S000002390	ORF	Verified	YDL231C	BRE4	4	42245	38868	C	Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport
10070	S000002389	ORF	Verified	YDL230W	PTP1	4	42701	43708	W	Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria
10072	S000002388	ORF	Verified	YDL229W	SSB1	4	44066	45907	W	Cytoplasmic ATPase that is a ribosome-associated molecular chaperone; may be involved in the folding of newly-synthesized polypeptide chains; member of the heat shock protein 70 (HSP70) family; interacts with the phosphatase subunit Reg1p
10074	S000002387	ORF	Dubious	YDL228C	n.a.	4	45919	45278	C	Hypothetical protein
10076	S000002386	ORF	Verified	YDL227C	HO	4	48032	46272	C	Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p
10078	S000002385	ORF	Verified	YDL226C	GCS1	4	52174	51116	C	ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p
10080	S000002384	ORF	Verified	YDL225W	SHS1	4	52446	54101	W	One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis
10082	S000002383	ORF	Verified	YDL224C	WHI4	4	56347	54398	C	Putative RNA binding protein and partially redundant Whi3p homolog that regulates the cell size requirement for passage through Start and commitment to cell division
10084	S000002382	ORF	Verified	YDL223C	HBT1	4	60406	57266	C	Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis
10086	S000002381	ORF	Uncharacterized	YDL222C	FMP45	4	61802	60873	C	The authentic, non-tagged protein was localized to the mitochondria; cell cortex protein; not required for growth on nonfermentable carbon sources; required for viability in stationary phase
10088	S000002380	ORF	Dubious	YDL221W	n.a.	4	62012	62563	W	Protein required for cell viability
10090	S000002379	ORF	Verified	YDL220C	CDC13	4	65019	62245	C	Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping
10092	S000002378	ORF	Verified	YDL219W	DTD1	4	65243	65766	W	D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes
10095	S000032534	intron	n.a.	n.a.	n.a.	4	65308	65378	W	n.a.
10096	S000002377	ORF	Uncharacterized	YDL218W	n.a.	4	66494	67447	W	Hypothetical protein
10098	S000002376	ORF	Verified	YDL217C	TIM22	4	68607	67984	C	Mitochondrial inner membrane protein involved in import of proteins of the ADP/ATP carrier (AAC) family
10100	S000002375	ORF	Verified	YDL216C	RRI1	4	70365	68998	C	Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling
10102	S000002374	ORF	Verified	YDL215C	GDH2	4	73919	70641	C	NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels
10104	S000002373	ORF	Verified	YDL214C	PRR2	4	76546	74447	C	Protein kinase with a possible role in MAP kinase signaling in the pheromone response pathway
10106	S000002372	ORF	Uncharacterized	YDL213C	NOP6	4	77967	77290	C	Protein with similarity to hydrophilins, which are involved in the adaptive response to hyperosmotic conditions; computational analysis of large-scale protein-protein interaction data suggests a possible role in rRNA processing
10108	S000002371	ORF	Verified	YDL212W	SHR3	4	78427	79059	W	Endoplasmic reticulum packaging chaperone, required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface
10110	S000002370	ORF	Uncharacterized	YDL211C	n.a.	4	80413	79295	C	Hypothetical protein
10112	S000006576	tRNA	n.a.	tG(GCC)D1	n.a.	4	83549	83619	W	tRNA-Gly
10114	S000002369	ORF	Verified	YDL210W	UGA4	4	84271	85986	W	Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane
10116	S000002368	ORF	Verified	YDL209C	CWC2	4	87227	86208	C	Protein involved in pre-mRNA splicing, component of a complex containing Cef1p; interacts with Prp19p; contains an RNA recognition motif; has similarity to S. pombe Cwf2p
10118	S000002367	ORF	Verified	YDL208W	NHP2	4	87462	87983	W	Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing
10120	S000002366	ORF	Verified	YDL207W	GLE1	4	88249	89865	W	Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component of Nup82p nuclear pore subcomplex; contains a nuclear export signal
10122	S000002365	ORF	Uncharacterized	YDL206W	n.a.	4	90177	92465	W	Hypothetical protein
10124	S000002364	ORF	Verified	YDL205C	HEM3	4	93746	92763	C	Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p
10126	S000002363	ORF	Verified	YDL204W	RTN2	4	94606	95787	W	Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily
10128	S000002362	ORF	Uncharacterized	YDL203C	n.a.	4	97954	96083	C	Hypothetical protein
10130	S000002361	ORF	Verified	YDL202W	MRPL11	4	98476	99225	W	Mitochondrial ribosomal protein of the large subunit
10132	S000002360	ORF	Verified	YDL201W	TRM8	4	99562	100422	W	Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA
10134	S000002359	ORF	Verified	YDL200C	MGT1	4	101122	100502	C	DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage
10136	S000002358	ORF	Uncharacterized	YDL199C	n.a.	4	103354	101291	C	Hypothetical protein
10138	S000002357	ORF	Verified	YDL198C	GGC1	4	104552	103650	C	Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family; (putative) mitochondrial carrier protein
10140	S000002356	ORF	Verified	YDL197C	ASF2	4	106495	104918	C	Anti-silencing protein that causes derepression of silent loci when overexpressed
10142	S000002355	ORF	Dubious	YDL196W	n.a.	4	106742	107071	W	Protein required for cell viability
10144	S000002354	ORF	Verified	YDL195W	SEC31	4	107209	111030	W	Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles, in complex with Sec13p; required for ER-derived transport vesicle formation
10146	S000002353	ORF	Verified	YDL194W	SNF3	4	111581	114235	W	Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4
10148	S000002352	ORF	Uncharacterized	YDL193W	n.a.	4	114673	115800	W	Protein required for cell viability
10150	S000002351	ORF	Verified	YDL192W	ARF1	4	116322	116867	W	ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p
10152	S000002350	ORF	Verified	YDL191W	RPL35A	4	117665	118518	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein
10155	S000033397	intron	n.a.	n.a.	n.a.	4	117668	118158	W	n.a.
10156	S000002349	ORF	Verified	YDL190C	UFD2	4	121593	118708	C	Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3
10158	S000002348	ORF	Verified	YDL189W	RBS1	4	122217	123590	W	Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain
10160	S000002347	ORF	Verified	YDL188C	PPH22	4	124999	123866	C	Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
10162	S000002345	ORF	Uncharacterized	YDL186W	n.a.	4	125617	126450	W	Hypothetical protein
10164	S000002346	ORF	Dubious	YDL187C	n.a.	4	125839	125510	C	Hypothetical protein
10166	S000002344	ORF	Verified	YDL185W	TFP1	4	126788	130003	W	Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease
10168	S000007600	ORF	Dubious	YDL185C-A	n.a.	4	126836	126609	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
10170	S000002343	ORF	Verified	YDL184C	RPL41A	4	130485	130408	C	Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Bp and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable
10172	S000002342	ORF	Uncharacterized	YDL183C	n.a.	4	131834	130872	C	Hypothetical protein
10174	S000002341	ORF	Verified	YDL182W	LYS20	4	133438	134724	W	Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p
10176	S000002340	ORF	Verified	YDL181W	INH1	4	135180	135437	W	Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase, inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p and both Inh1p and Stf1p exhibit the potential to form coiled-coil structures
10178	S000002339	ORF	Uncharacterized	YDL180W	n.a.	4	135897	137540	W	Hypothetical protein
10180	S000002338	ORF	Verified	YDL179W	PCL9	4	138292	139206	W	Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p
10182	S000002337	ORF	Verified	YDL178W	DLD2	4	139523	141115	W	D-lactate dehydrogenase, located in the mitochondrial matrix
10184	S000002336	ORF	Uncharacterized	YDL177C	n.a.	4	141722	141210	C	Hypothetical protein
10186	S000002335	ORF	Uncharacterized	YDL176W	n.a.	4	142098	144224	W	Hypothetical protein
10188	S000002334	ORF	Verified	YDL175C	AIR2	4	145519	144485	C	RING finger protein that interacts with the arginine methyltransferase Hmt1p; may regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air1p
10190	S000002333	ORF	Verified	YDL174C	DLD1	4	147590	145827	C	D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane
10192	S000002332	ORF	Uncharacterized	YDL173W	n.a.	4	148192	149079	W	Hypothetical protein
10194	S000002331	ORF	Dubious	YDL172C	n.a.	4	149087	148608	C	Hypothetical protein
10196	S000002330	ORF	Verified	YDL171C	GLT1	4	155641	149204	C	NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source
10198	S000002329	ORF	Verified	YDL170W	UGA3	4	156319	157905	W	Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus
10200	S000002328	ORF	Verified	YDL169C	UGX2	4	158736	158065	C	Protein of unknown function
10202	S000002327	ORF	Verified	YDL168W	SFA1	4	159605	160765	W	Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p
10204	S000002326	ORF	Verified	YDL167C	NRP1	4	163155	160996	C	Protein of unknown function, rich in asparagine residues
10206	S000002325	ORF	Verified	YDL166C	FAP7	4	164043	163450	C	Essential nuclear protein, involved in the oxidative stress response
10208	S000002324	ORF	Verified	YDL165W	CDC36	4	164291	164866	W	Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor
10210	S000002322	ORF	Dubious	YDL163W	n.a.	4	166957	167259	W	Protein required for cell viability
10212	S000002323	ORF	Verified	YDL164C	CDC9	4	167255	164988	C	DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination
10214	S000002320	ORF	Verified	YDL161W	ENT1	4	167715	169079	W	Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus
10216	S000002321	ORF	Dubious	YDL162C	n.a.	4	167716	167360	C	Hypothetical protein
10218	S000028520	ORF	Uncharacterized	YDL160C-A	n.a.	4	169609	169367	C	Identified by homology to <i>Ashbya gossypii</i>
10220	S000002319	ORF	Verified	YDL160C	DHH1	4	171931	170411	C	Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation
10222	S000007599	ORF	Uncharacterized	YDL159W-A	n.a.	4	172183	172314	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
10224	S000002318	ORF	Verified	YDL159W	STE7	4	172482	174029	W	Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway
10226	S000028612	ORF	Dubious	YDL159C-B	n.a.	4	173233	173057	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
10228	S000002317	ORF	Dubious	YDL158C	n.a.	4	174175	173867	C	Hypothetical protein
10230	S000002316	ORF	Uncharacterized	YDL157C	n.a.	4	174589	174233	C	Hypothetical protein
10232	S000002315	ORF	Uncharacterized	YDL156W	n.a.	4	174919	176487	W	Hypothetical protein
10234	S000002314	ORF	Verified	YDL155W	CLB3	4	176774	178057	W	B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation
10236	S000002313	ORF	Verified	YDL154W	MSH5	4	178335	181040	W	Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans
10238	S000002311	ORF	Dubious	YDL152W	n.a.	4	182823	183188	W	Protein required for cell viability
10240	S000002312	ORF	Verified	YDL153C	SAS10	4	183019	181187	C	Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing; essential nucleolar protein that, when overproduced, disrupts silencing
10242	S000002309	ORF	Verified	YDL150W	RPC53	4	183344	184612	W	RNA polymerase III subunit C53
10244	S000002310	ORF	Dubious	YDL151C	BUD30	4	183900	183319	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 96% of ORF overlaps the verified gene RPC53; diploid mutant displays a weak budding pattern phenotype in a systematic assay
10246	S000002308	ORF	Verified	YDL149W	ATG9	4	184926	187919	W	Transmembrane protein involved in formation of Cvt and autophagic vesicles; cycles between the pre-autophagosomal structure and other cytosolic punctate structures, not found in autophagosomes
10248	S000002307	ORF	Verified	YDL148C	NOP14	4	190587	188155	C	Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA
10250	S000002306	ORF	Verified	YDL147W	RPN5	4	190925	192262	W	Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p
10252	S000002305	ORF	Uncharacterized	YDL146W	n.a.	4	192751	194226	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck
10254	S000002304	ORF	Verified	YDL145C	COP1	4	198177	194572	C	Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway
10256	S000002303	ORF	Uncharacterized	YDL144C	n.a.	4	199733	198663	C	Hypothetical protein
10258	S000002302	ORF	Verified	YDL143W	CCT4	4	199997	201583	W	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
10260	S000002301	ORF	Verified	YDL142C	CRD1	4	202571	201720	C	Cardiolipin synthase; produces cardiolipin, which is an important constituent of mitochondrial membranes; required for normal mitochondrial membrane potential and function
10262	S000002300	ORF	Verified	YDL141W	BPL1	4	203040	205112	W	Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation
10264	S000002299	ORF	Verified	YDL140C	RPO21	4	210562	205361	C	RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime
10266	S000002298	ORF	Uncharacterized	YDL139C	SCM3	4	212047	211376	C	Protein of unknown function; isolated as a high-copy suppressor of mutations in the histone fold domain (HFD) of CSE4
10268	S000002297	ORF	Verified	YDL138W	RGT2	4	213352	215643	W	Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes
10270	S000002296	ORF	Verified	YDL137W	ARF2	4	216529	217074	W	ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p
10272	S000002295	ORF	Verified	YDL136W	RPL35B	4	217600	218367	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein
10275	S000036639	intron	n.a.	n.a.	n.a.	4	217603	218007	W	n.a.
10276	S000002294	ORF	Verified	YDL135C	RDI1	4	219288	218680	C	Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p
10278	S000002292	ORF	Verified	YDL134C	PPH21	4	220771	219662	C	Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis
10280	S000002293	ORF	Verified	YDL133C-A	RPL41B	4	221801	221724	C	Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Ap and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable
10282	S000002291	ORF	Uncharacterized	YDL133W	n.a.	4	222427	223740	W	Hypothetical protein
10284	S000002290	ORF	Verified	YDL132W	CDC53	4	224304	226751	W	Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation
10286	S000002289	ORF	Verified	YDL131W	LYS21	4	227393	228715	W	Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p
10288	S000007232	ORF	Verified	YDL130W-A	STF1	4	229171	229431	W	Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein
10290	S000002288	ORF	Verified	YDL130W	RPP1B	4	229906	230527	W	Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component
10293	S000035363	intron	n.a.	n.a.	n.a.	4	230020	230320	W	n.a.
10294	S000002287	ORF	Uncharacterized	YDL129W	n.a.	4	231024	231899	W	Hypothetical protein
10296	S000002286	ORF	Verified	YDL128W	VCX1	4	232652	233887	W	Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter
10298	S000002285	ORF	Verified	YDL127W	PCL2	4	234927	235853	W	G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to entry into the mitotic cell cycle, essential for cell morphogenesis; localizes to sites of polarized cell growth
10300	S000002284	ORF	Verified	YDL126C	CDC48	4	238664	236157	C	ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome
10302	S000002283	ORF	Verified	YDL125C	HNT1	4	239606	239019	C	Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint
10305	S000033249	intron	n.a.	n.a.	n.a.	4	239509	239399	C	n.a.
10306	S000002282	ORF	Verified	YDL124W	n.a.	4	240259	241197	W	NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters
10308	S000002281	ORF	Verified	YDL123W	SNA4	4	241418	241840	W	Protein of unknown function, localized to the vacuolar outer membrane
10310	S000002280	ORF	Verified	YDL122W	UBP1	4	242552	244981	W	Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains
10312	S000002279	ORF	Uncharacterized	YDL121C	n.a.	4	245582	245133	C	Hypothetical protein
10314	S000002278	ORF	Verified	YDL120W	YFH1	4	245923	246447	W	Yeast Frataxin Homologue; mitochondrial protein that regulates mitochondrial iron accumulation
10316	S000002276	ORF	Dubious	YDL118W	n.a.	4	247302	247682	W	Hypothetical protein
10318	S000002277	ORF	Uncharacterized	YDL119C	n.a.	4	247612	246689	C	Hypothetical protein
10320	S000002275	ORF	Verified	YDL117W	CYK3	4	248581	251238	W	SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis
10322	S000002274	ORF	Verified	YDL116W	NUP84	4	251566	253746	W	Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis
10324	S000002273	ORF	Uncharacterized	YDL115C	IWR1	4	254717	253995	C	Protein of unknown function, deletion causes hypersensitivity to the K1 killer toxin
10326	S000007598	ORF	Dubious	YDL114W-A	n.a.	4	254935	255048	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
10328	S000002272	ORF	Uncharacterized	YDL114W	n.a.	4	255604	256530	W	Hypothetical protein
10330	S000002271	ORF	Verified	YDL113C	ATG20	4	258555	256633	C	Protein required for transport of aminopeptidase I (Lap4p) through the cytoplasm-to-vacuole targeting pathway; binds phosphatidylinositol-3-phosphate, involved in localization of membranes to the preautophagosome, potential Cdc28p substrate
10332	S000002270	ORF	Verified	YDL112W	TRM3	4	258915	263225	W	2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs
10334	S000002269	ORF	Verified	YDL111C	RRP42	4	264110	263313	C	Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp4p, Rrp41p, Rrp43p and Dis3p
10336	S000002268	ORF	Uncharacterized	YDL110C	n.a.	4	264964	264512	C	Hypothetical protein
10338	S000002267	ORF	Uncharacterized	YDL109C	n.a.	4	267201	265258	C	Hypothetical protein
10340	S000002266	ORF	Verified	YDL108W	KIN28	4	267698	268699	W	Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters
10343	S000033870	intron	n.a.	n.a.	n.a.	4	267726	267806	W	n.a.
10344	S000002265	ORF	Verified	YDL107W	MSS2	4	268921	269976	W	Peripherally bound inner membrane protein of the mitochondrial matrix, required for export of C-terminal tail of Cox2p through the inner membrane
10346	S000002264	ORF	Verified	YDL106C	PHO2	4	271901	270222	C	Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p
10348	S000002263	ORF	Verified	YDL105W	NSE4	4	272389	273597	W	Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex
10350	S000002262	ORF	Uncharacterized	YDL104C	QRI7	4	274876	273653	C	Putative metalloprotease, similar to O-sialoglycoprotein metallopeptidase from P. haemolytica
10352	S000002261	ORF	Verified	YDL103C	QRI1	4	276581	275148	C	UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis
10354	S000002260	ORF	Verified	YDL102W	CDC2	4	276872	280165	W	Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)
10356	S000002259	ORF	Verified	YDL101C	DUN1	4	281848	280307	C	Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair
10358	S000002258	ORF	Verified	YDL100C	ARR4	4	283176	282112	C	ATPase, involved in resistance to heat and metal stress, active as a dimer; normally localized to the cytosol, but appears to localize to late endosomes under stress conditions
10360	S000002257	ORF	Uncharacterized	YDL099W	n.a.	4	283419	284444	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
10362	S000002256	ORF	Verified	YDL098C	SNU23	4	285165	284581	C	23 kD U4/U6.U5 snRNP associated protein; Putative RNA binding zinc finger protein
10364	S000002255	ORF	Verified	YDL097C	RPN6	4	286695	285391	C	Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for the assembly and activity of the 26S proteasome; the human homolog (S9 protein) partially rescues Rpn6p depletion
10366	S000002253	ORF	Verified	YDL095W	PMT1	4	287059	289512	W	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals
10368	S000002254	ORF	Dubious	YDL096C	n.a.	4	287324	286998	C	Hypothetical protein
10370	S000002251	ORF	Verified	YDL093W	PMT5	4	289909	292140	W	Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals
10372	S000002252	ORF	Dubious	YDL094C	n.a.	4	290081	289572	C	Hypothetical protein
10374	S000002250	ORF	Verified	YDL092W	SRP14	4	292781	293221	W	Signal recognition particle (SRP) subunit, interacts with the RNA component of SRP to form the Alu domain, which is the region of SRP responsible for arrest of nascent chain elongation during membrane targeting; homolog of mammalian SRP14
10376	S000002249	ORF	Uncharacterized	YDL091C	UBX3	4	294759	293392	C	UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
10378	S000002248	ORF	Verified	YDL090C	RAM1	4	296329	295034	C	Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit
10380	S000002247	ORF	Uncharacterized	YDL089W	n.a.	4	296820	298274	W	Protein of unknown function; interacts with meiotic division protein Csm1p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, potential Cdc28p substrate
10382	S000002246	ORF	Verified	YDL088C	ASM4	4	300003	298417	C	Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p
10384	S000002245	ORF	Verified	YDL087C	LUC7	4	300999	300214	C	Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site
10386	S000002244	ORF	Uncharacterized	YDL086W	n.a.	4	301413	302234	W	Hypothetical protein
10388	S000028611	ORF	Dubious	YDL086C-A	n.a.	4	302089	301655	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
10390	S000007588	ORF	Uncharacterized	YDL085C-A	n.a.	4	302670	302464	C	Hypothetical protein
10392	S000002243	ORF	Verified	YDL085W	NDE2	4	303211	304848	W	Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain
10394	S000002242	ORF	Verified	YDL084W	SUB2	4	305237	306577	W	Component of the TREX complex required for nuclear mRNA export; DEAD-box RNA helicase involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56
10396	S000002241	ORF	Verified	YDL083C	RPS16B	4	307789	306926	C	Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins
10399	S000035914	intron	n.a.	n.a.	n.a.	4	307765	307334	C	n.a.
10400	S000002240	ORF	Verified	YDL082W	RPL13A	4	308424	309388	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein
10403	S000035862	intron	n.a.	n.a.	n.a.	4	308428	308792	W	n.a.
10404	S000002239	ORF	Verified	YDL081C	RPP1A	4	310122	309802	C	Ribosomal protein P1 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component
10406	S000002238	ORF	Verified	YDL080C	THI3	4	312471	310642	C	Probable decarboxylase, required for expression of enzymes involved in thiamine biosynthesis; may have a role in catabolism of amino acids to long-chain and complex alcohols
10408	S000002237	ORF	Verified	YDL079C	MRK1	4	314748	312951	C	Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation
10411	S000033719	intron	n.a.	n.a.	n.a.	4	314336	314045	C	n.a.
10412	S000002236	ORF	Verified	YDL078C	MDH3	4	316388	315357	C	Cytoplasmic malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle
10414	S000002235	ORF	Verified	YDL077C	VAM6	4	320120	316971	C	Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by facilitating guanine nucleotide exchange on small guanosine triphosphatase Ypt7p
10416	S000002234	ORF	Uncharacterized	YDL076C	RXT3	4	321552	320668	C	Protein of unknown function, may be involved in chromatin silencing
10418	S000002233	ORF	Verified	YDL075W	RPL31A	4	322226	322988	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p
10421	S000032746	intron	n.a.	n.a.	n.a.	4	322283	322703	W	n.a.
10422	S000006454	snoRNA	n.a.	snR63	SNR63	4	323471	323217	C	guides 2'-O-methylation on large subunit rRNA at A2254; small nucleolar RNA snR63
10424	S000002232	ORF	Verified	YDL074C	BRE1	4	326149	324047	C	E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on L4 and L79), contains RING finger domain
10426	S000002231	ORF	Uncharacterized	YDL073W	n.a.	4	326613	329567	W	Hypothetical protein
10428	S000002230	ORF	Uncharacterized	YDL072C	n.a.	4	330447	329836	C	Endoplasmic reticulum transmembrane protein, homolog of human BAP31 protein
10430	S000002228	ORF	Verified	YDL070W	BDF2	4	331025	332941	W	Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p
10432	S000002229	ORF	Dubious	YDL071C	n.a.	4	331041	330667	C	Hypothetical protein
10434	S000002226	ORF	Dubious	YDL068W	n.a.	4	333500	333829	W	Hypothetical protein
10436	S000002227	ORF	Verified	YDL069C	CBS1	4	333810	333121	C	translational activator of cytochrome b
10438	S000002225	ORF	Verified	YDL067C	COX9	4	334396	334217	C	Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain
10440	S000002224	ORF	Verified	YDL066W	IDP1	4	334835	336121	W	Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes
10442	S000002223	ORF	Verified	YDL065C	PEX19	4	337301	336249	C	Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane
10444	S000002222	ORF	Verified	YDL064W	UBC9	4	337487	338070	W	SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC)
10447	S000036732	intron	n.a.	n.a.	n.a.	4	337525	337634	W	n.a.
10448	S000002220	ORF	Dubious	YDL062W	n.a.	4	339857	340282	W	Hypothetical protein
10450	S000002221	ORF	Uncharacterized	YDL063C	n.a.	4	340134	338272	C	Hypothetical protein
10452	S000002219	ORF	Verified	YDL061C	RPS29B	4	340798	340628	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Ap and has similarity to rat S29 and E. coli S14 ribosomal proteins
10454	S000002218	ORF	Verified	YDL060W	TSR1	4	341619	343985	W	Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles
10456	S000002217	ORF	Verified	YDL059C	RAD59	4	344953	344237	C	Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; homologous to Rad52p
10458	S000002216	ORF	Verified	YDL058W	USO1	4	345665	351037	W	Essential protein involved in intracellular protein transport, coiled-coil protein necessary for transport from ER to Golgi; required for assembly of the ER-to-Golgi SNARE complex
10460	S000002215	ORF	Uncharacterized	YDL057W	n.a.	4	351434	352420	W	Hypothetical protein
10462	S000002214	ORF	Verified	YDL056W	MBP1	4	352877	355378	W	Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes
10464	S000002213	ORF	Verified	YDL055C	PSA1	4	356759	355674	C	GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure
10466	S000006629	tRNA	n.a.	tK(UUU)D	n.a.	4	359577	359672	W	tRNA-Lys
10467	S000034182	intron	n.a.	n.a.	n.a.	4	359614	359636	W	n.a.
10470	S000002212	ORF	Verified	YDL054C	MCH1	4	361285	359825	C	Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport
10472	S000002211	ORF	Uncharacterized	YDL053C	PBP4	4	362256	361699	C	Pbp1p binding protein, interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system
10474	S000002210	ORF	Verified	YDL052C	SLC1	4	363583	362672	C	1-acyl-sn-gylcerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; located in lipid particles and endoplasmic reticulum
10476	S000002209	ORF	Verified	YDL051W	LHP1	4	363952	364779	W	RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen
10478	S000002208	ORF	Dubious	YDL050C	n.a.	4	364817	364446	C	Hypothetical protein
10480	S000002207	ORF	Verified	YDL049C	KNH1	4	365874	365068	C	Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis; overproduction suppresses growth defects of a kre9 null mutant
10482	S000002206	ORF	Verified	YDL048C	STP4	4	368211	366739	C	Protein involved in pre-tRNA splicing and in uptake of branched-chain amino acids
10484	S000002205	ORF	Verified	YDL047W	SIT4	4	369769	370704	W	Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization
10486	S000002204	ORF	Uncharacterized	YDL046W	n.a.	4	371237	371758	W	Putative homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes
10488	S000006430	ORF	Verified	YDL045W-A	MRP10	4	372245	372532	W	Mitochondrial ribosomal protein of the small subunit
10490	S000002203	ORF	Verified	YDL045C	FAD1	4	373605	372685	C	Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin
10492	S000002202	ORF	Verified	YDL044C	MTF2	4	375286	373964	C	Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription
10494	S000002201	ORF	Verified	YDL043C	PRP11	4	376477	375677	C	Subunit of the SF3a splicing factor complex, required for spliceosome assembly
10496	S000002199	ORF	Dubious	YDL041W	n.a.	4	378099	378452	W	Hypothetical protein
10498	S000002200	ORF	Verified	YDL042C	SIR2	4	378442	376754	C	Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan;  plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication
10500	S000002198	ORF	Verified	YDL040C	NAT1	4	381435	378871	C	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
10502	S000002197	ORF	Verified	YDL039C	PRM7	4	382330	381983	C	Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements
10504	S000002196	ORF	Uncharacterized	YDL038C	n.a.	4	384078	382327	C	Hypothetical protein
10506	S000002195	ORF	Verified	YDL037C	BSC1	4	385584	384598	C	Protein of unconfirmed function, similar to cell surface flocculin Muc1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
10508	S000002194	ORF	Uncharacterized	YDL036C	n.a.	4	388898	387510	C	Hypothetical protein
10510	S000002192	ORF	Dubious	YDL034W	n.a.	4	391780	392124	W	Hypothetical protein
10512	S000002193	ORF	Verified	YDL035C	GPR1	4	392054	389169	C	Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis
10514	S000002190	ORF	Dubious	YDL032W	n.a.	4	393687	393998	W	Hypothetical protein
10516	S000002191	ORF	Uncharacterized	YDL033C	SLM3	4	393909	392656	C	tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)
10518	S000002189	ORF	Verified	YDL031W	DBP10	4	394214	397201	W	Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis
10520	S000002188	ORF	Verified	YDL030W	PRP9	4	397534	399126	W	Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex
10522	S000002187	ORF	Verified	YDL029W	ARP2	4	399337	400635	W	Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity
10525	S000032600	intron	n.a.	n.a.	n.a.	4	399359	399481	W	n.a.
10526	S000002186	ORF	Verified	YDL028C	MPS1	4	403288	400994	C	Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p
10528	S000002184	ORF	Dubious	YDL026W	n.a.	4	404746	405057	W	Hypothetical protein
10530	S000002185	ORF	Uncharacterized	YDL027C	n.a.	4	404954	403692	C	Hypothetical protein
10532	S000028610	ORF	Dubious	YDL025W-A	n.a.	4	405407	405511	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
10534	S000002183	ORF	Uncharacterized	YDL025C	n.a.	4	407203	405341	C	Protein of unknown function, potentially phosphorylated by Cdc28p
10536	S000002182	ORF	Verified	YDL024C	DIA3	4	409854	408448	C	Protein of unknown function, involved in invasive and pseudohyphal growth
10538	S000028537	ORF	Dubious	YDL022C-A	n.a.	4	410053	409805	C	Identified by fungal homology and RT-PCR
10540	S000006510	tRNA	n.a.	tA(AGC)D	n.a.	4	410376	410448	W	tRNA-Ala
10542	S000002180	ORF	Verified	YDL022W	GPD1	4	411822	412997	W	NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p
10544	S000002181	ORF	Dubious	YDL023C	n.a.	4	412078	411758	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 80% of ORF overlaps the verified gene GPD1; deletion in cyr1 mutant results in loss of stress resistance
10546	S000002179	ORF	Verified	YDL021W	GPM2	4	413950	414885	W	Homolog of Gpm1p phosphoglycerate mutase which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event
10548	S000002178	ORF	Verified	YDL020C	RPN4	4	416705	415110	C	Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses
10550	S000002177	ORF	Verified	YDL019C	OSH2	4	421511	417660	C	Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability
10552	S000002176	ORF	Verified	YDL018C	ERP3	4	423507	422830	C	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
10554	S000002175	ORF	Verified	YDL017W	CDC7	4	424206	425729	W	DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression
10556	S000002174	ORF	Dubious	YDL016C	n.a.	4	425869	425567	C	Protein required for cell viability
10558	S000002173	ORF	Verified	YDL015C	TSC13	4	426931	425999	C	Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p
10560	S000002172	ORF	Verified	YDL014W	NOP1	4	427361	428344	W	Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin
10562	S000002171	ORF	Verified	YDL013W	HEX3	4	429064	430923	W	Ring finger protein involved in the DNA damage response with possible recombination role; genetically identified by synthetic lethality with SGS1 (DNA helicase) and TOP3 (DNA topoisomerase); sporulation role; interacts with Slx8p and Lin1p
10564	S000002170	ORF	Uncharacterized	YDL012C	n.a.	4	431514	431105	C	Plasma membrane protein of unknown function
10567	S000033171	intron	n.a.	n.a.	n.a.	4	431469	431384	C	n.a.
10568	S000002168	ORF	Uncharacterized	YDL010W	n.a.	4	432327	433022	W	Hypothetical protein
10570	S000002169	ORF	Dubious	YDL011C	n.a.	4	432628	432305	C	Hypothetical protein
10572	S000002167	ORF	Dubious	YDL009C	n.a.	4	433245	432922	C	Hypothetical protein
10574	S000002166	ORF	Verified	YDL008W	APC11	4	433494	433991	W	Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
10576	S000006739	tRNA	n.a.	tT(AGU)D	n.a.	4	434333	434261	C	tRNA-Thr
10580	S000006721	tRNA	n.a.	tS(AGA)D1	n.a.	4	437769	437850	W	tRNA-Ser
10582	S000002165	ORF	Verified	YDL007W	RPT2	4	438044	439357	W	One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle
10584	S000002164	ORF	Verified	YDL006W	PTC1	4	439906	440751	W	Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation
10586	S000002163	ORF	Verified	YDL005C	MED2	4	442306	441011	C	RNA Polymerase II transcriptional regulation mediator; Stoichiometric member of mediator complex
10588	S000002162	ORF	Verified	YDL004W	ATP16	4	443026	443508	W	Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
10590	S000002161	ORF	Verified	YDL003W	MCD1	4	444680	446380	W	Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase
10592	S000002160	ORF	Verified	YDL002C	NHP10	4	447575	446964	C	Protein related to mammalian high mobility group proteins; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex
10594	S000002159	ORF	Verified	YDL001W	RMD1	4	447981	449273	W	Cytoplasmic protein required for sporulation
10600	S000002408	ORF	Verified	YDR001C	NTH1	4	452472	450217	C	Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p
10602	S000002409	ORF	Verified	YDR002W	YRB1	4	453042	453647	W	Yeast Ran Binder #1; suppressor of FUS1; homolog of mouse HTF9a and human RanBP1; nuclear GTPase-activating protein for Ran
10604	S000002410	ORF	Verified	YDR003W	RCR2	4	454119	454751	W	Endoplasmic reticulum membrane protein with similarity to Rcr1p; C-terminal region can functionally replace the corresponding region of Rcr1p in conferring Congo Red resistance when overexpressed
10606	S000028819	ORF	Uncharacterized	YDR003W-A	n.a.	4	454779	454901	W	Identified by expression profiling and mass spectrometry
10608	S000002411	ORF	Verified	YDR004W	RAD57	4	455198	456580	W	Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p
10610	S000002412	ORF	Verified	YDR005C	MAF1	4	458100	456833	C	Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB
10613	S000034764	intron	n.a.	n.a.	n.a.	4	458094	458015	C	n.a.
10614	S000002413	ORF	Verified	YDR006C	SOK1	4	461244	458539	C	Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13
10616	S000002414	ORF	Verified	YDR007W	TRP1	4	461839	462513	W	Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)
10618	S000002415	ORF	Dubious	YDR008C	n.a.	4	462599	462249	C	Hypothetical protein
10620	S000002416	ORF	Verified	YDR009W	GAL3	4	463431	464993	W	Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p and Gal4p to relieve inhibition by Gal80p; binds galactose and ATP but does not have galactokinase activity
10622	S000002417	ORF	Dubious	YDR010C	n.a.	4	465380	465048	C	Hypothetical protein
10624	S000002418	ORF	Verified	YDR011W	SNQ2	4	465916	470421	W	ABC transporter protein involved in multidrug resistance and resistance to singlet oxygen species
10626	S000002419	ORF	Verified	YDR012W	RPL4B	4	471850	472938	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Ap and has similarity to E. coli L4 and rat L4 ribosomal proteins
10628	S000002420	ORF	Verified	YDR013W	PSF1	4	473154	473780	W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
10630	S000002421	ORF	Verified	YDR014W	RAD61	4	474043	475986	W	Protein of unknown function; mutation confers radiation sensitivity
10632	S000002422	ORF	Dubious	YDR015C	n.a.	4	478195	477806	C	Hypothetical protein
10634	S000002423	ORF	Verified	YDR016C	DAD1	4	478754	478470	C	Essential protein, component of the DASH complex, involved in spindle integrity and kinetochore function; interacts with Duo1p and Dam1p; localizes to intranuclear spindles and kinetochore
10636	S000002424	ORF	Verified	YDR017C	KCS1	4	482263	479111	C	Inositol hexaphosphate kinase, phosphorylates inositol hexakisphosphate (InsP6) to diphosphoinositol polyphosphates, required for proper vacuole morphology and involved in salt stress response, contains two leucine heptad repeats
10638	S000002425	ORF	Uncharacterized	YDR018C	n.a.	4	483856	482666	C	Hypothetical protein
10640	S000002426	ORF	Verified	YDR019C	GCV1	4	485361	484159	C	T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm
10642	S000002427	ORF	Uncharacterized	YDR020C	n.a.	4	486440	485742	C	Hypothetical protein
10644	S000002428	ORF	Verified	YDR021W	FAL1	4	486800	487999	W	Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases
10646	S000002429	ORF	Verified	YDR022C	CIS1	4	488658	488068	C	Protein of unknown function that may be involved in microtubule organization; high-copy suppressor of CIK1 deletion
10648	S000006770	tRNA	n.a.	tV(UAC)D	n.a.	4	488866	488793	C	tRNA-Val
10650	S000002430	ORF	Verified	YDR023W	SES1	4	489504	490892	W	Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p
10652	S000002431	ORF	Dubious	YDR024W	FYV1	4	491013	491498	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; mutation decreases survival upon exposure to K1 killer toxin
10654	S000002432	ORF	Verified	YDR025W	RPS11A	4	491511	492320	W	Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins
10657	S000033921	intron	n.a.	n.a.	n.a.	4	491556	491894	W	n.a.
10658	S000002433	ORF	Uncharacterized	YDR026C	n.a.	4	494264	492552	C	Hypothetical protein
10660	S000002434	ORF	Verified	YDR027C	VPS54	4	497314	494645	C	Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p
10662	S000002435	ORF	Verified	YDR028C	REG1	4	500875	497831	C	Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes; involved in RNA processing
10664	S000002436	ORF	Dubious	YDR029W	n.a.	4	501096	501410	W	Hypothetical protein
10666	S000002437	ORF	Verified	YDR030C	RAD28	4	503269	501749	C	Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSA protein
10668	S000002438	ORF	Uncharacterized	YDR031W	n.a.	4	503494	503859	W	Hypothetical protein
10670	S000002439	ORF	Verified	YDR032C	PST2	4	504691	504095	C	Protein of unknown function with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; GFP-fusion protein localizes to the cytoplasm in a punctate pattern
10672	S000002440	ORF	Verified	YDR033W	MRH1	4	508143	509105	W	Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; has similarity to Hsp30p and Yro2p, which are induced during heat shock
10674	S000002441	ORF	Verified	YDR034C	LYS14	4	512105	509733	C	Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer
10687	S000006649	tRNA	n.a.	tL(UAA)D	n.a.	4	519739	519822	W	tRNA-Leu
10691	S000007233	ORF	Uncharacterized	YDR034C-A	n.a.	4	520688	520512	C	Similar to probable membrane protein YLR334C and ORF YOL106W
10694	S000006693	tRNA	n.a.	tQ(UUG)D1	n.a.	4	520968	521039	W	tRNA-Gln
10696	S000007234	ORF	Uncharacterized	YDR034W-B	n.a.	4	521310	521465	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
10698	S000002442	ORF	Verified	YDR035W	ARO3	4	521812	522924	W	3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine
10700	S000002443	ORF	Verified	YDR036C	EHD3	4	524709	523207	C	Protein of unconfirmed function, plays an indirect role in endocytic membrane trafficking, member of a family of enoyl-CoA hydratase/isomerases
10702	S000002444	ORF	Verified	YDR037W	KRS1	4	525436	527211	W	Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis
10704	S000002445	ORF	Verified	YDR038C	ENA5	4	530693	527418	C	Protein with similarity to P-type ATPase sodium pumps
10706	S000002446	ORF	Verified	YDR039C	ENA2	4	534578	531303	C	P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux
10708	S000002447	ORF	Verified	YDR040C	ENA1	4	538463	535188	C	P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance
10710	S000002448	ORF	Verified	YDR041W	RSM10	4	539799	540410	W	Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins
10712	S000002449	ORF	Uncharacterized	YDR042C	n.a.	4	541199	540597	C	Hypothetical protein
10714	S000006507	snoRNA	n.a.	snR47	SNR47	4	541741	541643	C	small nucleolar RNA snR47
10716	S000002450	ORF	Verified	YDR043C	NRG1	4	543366	542671	C	Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response
10718	S000002451	ORF	Verified	YDR044W	HEM13	4	546639	547625	W	Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)
10720	S000002452	ORF	Verified	YDR045C	RPC11	4	548307	547975	C	RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription
10722	S000002453	ORF	Verified	YDR046C	BAP3	4	550573	548759	C	Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine
10724	S000002454	ORF	Verified	YDR047W	HEM12	4	551857	552945	W	Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents
10726	S000002456	ORF	Uncharacterized	YDR049W	n.a.	4	553251	555149	W	Hypothetical protein
10728	S000002455	ORF	Dubious	YDR048C	n.a.	4	553395	553081	C	Hypothetical protein
10730	S000002457	ORF	Verified	YDR050C	TPI1	4	556469	555723	C	Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region
10732	S000002458	ORF	Uncharacterized	YDR051C	n.a.	4	558057	557053	C	Hypothetical protein
10734	S000002460	ORF	Dubious	YDR053W	n.a.	4	560246	560641	W	Protein required for cell viability
10736	S000002459	ORF	Verified	YDR052C	DBF4	4	560622	558508	C	Regulatory subunit of Cdc7p-Dbf4p kinase complex, required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated
10738	S000002461	ORF	Verified	YDR054C	CDC34	4	562324	561437	C	Ubiquitin-conjugating enzyme or E2; together with Skp1p, Rbx1p, Cdc53p, and an F-box protein, forms a ubiquitin-protein ligase called the SCF complex which regulates cell cycle progression by targeting key substrates for degradation
10740	S000002462	ORF	Verified	YDR055W	PST1	4	563524	564858	W	Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1
10742	S000002463	ORF	Uncharacterized	YDR056C	n.a.	4	565637	565020	C	Hypothetical protein
10744	S000002464	ORF	Verified	YDR057W	YOS9	4	565924	567552	W	Glycoprotein of the ER membrane, involved in ER-to-Golgi transport of glycosylphosphatidylinositol (GPI)-anchored proteins
10746	S000002465	ORF	Verified	YDR058C	TGL2	4	568700	567720	C	Protein with lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli; role in yeast lipid degradation is unclear
10748	S000006709	tRNA	n.a.	tR(UCU)D	n.a.	4	568879	568950	W	tRNA-Arg
10750	S000006531	tRNA	n.a.	tD(GUC)D	n.a.	4	568961	569032	W	tRNA-Asp
10752	S000002466	ORF	Verified	YDR059C	UBC5	4	569767	569231	C	Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins, central component of the cellular stress response; expression is heat inducible
10755	S000031455	intron	n.a.	n.a.	n.a.	4	569720	569631	C	n.a.
10756	S000002467	ORF	Verified	YDR060W	MAK21	4	570645	573722	W	Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein
10758	S000002468	ORF	Uncharacterized	YDR061W	n.a.	4	574160	575779	W	Mitochondrial protein, member of the ATP-binding cassette (ABC) transporter family; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance
10760	S000002469	ORF	Verified	YDR062W	LCB2	4	576470	578155	W	Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine
10762	S000002470	ORF	Uncharacterized	YDR063W	n.a.	4	578660	579109	W	Hypothetical protein
10764	S000002471	ORF	Verified	YDR064W	RPS13	4	579455	580449	W	Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins
10767	S000032958	intron	n.a.	n.a.	n.a.	4	579476	580014	W	n.a.
10768	S000002472	ORF	Uncharacterized	YDR065W	n.a.	4	580684	581781	W	Hypothetical protein
10770	S000002473	ORF	Uncharacterized	YDR066C	n.a.	4	582495	581905	C	Hypothetical protein
10772	S000002474	ORF	Uncharacterized	YDR067C	n.a.	4	583462	582788	C	Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
10774	S000002475	ORF	Verified	YDR068W	DOS2	4	583710	584642	W	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
10776	S000002476	ORF	Verified	YDR069C	DOA4	4	587716	584936	C	Ubiquitin hydrolase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole
10778	S000002477	ORF	Uncharacterized	YDR070C	n.a.	4	588376	588095	C	The authentic, non-tagged protein was localized to the mitochondria
10780	S000002478	ORF	Verified	YDR071C	PAA1	4	589399	588824	C	Polyamine acetyltransferase; acetylates polyamines such as putrescine, spermidine and spermine; may be involved in transcription and/or DNA replication via regulation of levels of polyamines bound to chromosomal DNA
10782	S000002479	ORF	Verified	YDR072C	IPT1	4	591341	589758	C	Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
10784	S000002480	ORF	Verified	YDR073W	SNF11	4	592435	592944	W	One of 11 subunits of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p
10786	S000002481	ORF	Verified	YDR074W	TPS2	4	593889	596579	W	Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway
10788	S000002482	ORF	Verified	YDR075W	PPH3	4	597152	598078	W	Catalytic subunit of protein phosphatase; involved in activation of Gln3p, which is a transcription factor with a role in nitrogen utilization
10790	S000002483	ORF	Verified	YDR076W	RAD55	4	598464	599684	W	Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p
10792	S000002484	ORF	Verified	YDR077W	SED1	4	600789	601805	W	Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites
10794	S000002485	ORF	Uncharacterized	YDR078C	SHU2	4	602865	602194	C	Protein of unassigned function involved in mutation suppression, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p
10796	S000002486	ORF	Verified	YDR079W	PET100	4	603060	603395	W	Chaperone that specifically facilitates the assembly of cytochrome c oxidase, located in the mitochondrial inner membrane
10798	S000007603	ORF	Verified	YDR079C-A	TFB5	4	603807	603589	C	Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation; homolog of the Chlamydomonas reinhardtii REX1-S protein which is involved in DNA repair
10800	S000002487	ORF	Verified	YDR080W	VPS41	4	604004	606982	W	Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport
10802	S000002488	ORF	Verified	YDR081C	PDC2	4	610077	607300	C	Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes
10804	S000002489	ORF	Verified	YDR082W	STN1	4	610437	611921	W	Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping
10806	S000002490	ORF	Verified	YDR083W	RRP8	4	612069	613220	W	Protein involved in rRNA processing; involved in pre-rRNA cleavage at site A2; mutation is synthetically lethal with a gar1 mutation
10808	S000002491	ORF	Uncharacterized	YDR084C	n.a.	4	613999	613400	C	Integral membrane protein localized to vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
10810	S000002492	ORF	Verified	YDR085C	AFR1	4	616145	614283	C	Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; interacts with Cdc12p
10812	S000002493	ORF	Verified	YDR086C	SSS1	4	617165	616923	C	Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p
10814	S000002494	ORF	Verified	YDR087C	RRP1	4	618301	617465	C	Essential evolutionarily conserved nucleolar protein necessary for biogenesis of 60S ribosomal subunits and processing of pre-rRNAs to mature rRNAs, associated with several distinct 66S pre-ribosomal particles
10816	S000002495	ORF	Verified	YDR088C	SLU7	4	619640	618492	C	Protein involved in 3' splice site choices, acts in concert with Prp18p during the 2nd step of splicing
10818	S000006700	tRNA	n.a.	tR(ACG)D	n.a.	4	620036	619964	C	tRNA-Arg
10820	S000002496	ORF	Uncharacterized	YDR089W	n.a.	4	622107	624716	W	Hypothetical protein
10822	S000002497	ORF	Uncharacterized	YDR090C	n.a.	4	625993	625061	C	Hypothetical protein
10824	S000002498	ORF	Verified	YDR091C	RLI1	4	628529	626703	C	Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase
10826	S000002499	ORF	Verified	YDR092W	UBC13	4	629871	630600	W	Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus
10829	S000035562	intron	n.a.	n.a.	n.a.	4	629901	630168	W	n.a.
10830	S000002500	ORF	Verified	YDR093W	DNF2	4	631277	636115	W	Non-essential P-type ATPase that is a potential aminophospholipid translocase, localizes to the plasma membrane and late exocytic or early endocytic membranes, likely involved in protein transport; potential Cdc28p substrate
10832	S000002501	ORF	Dubious	YDR094W	n.a.	4	635835	636170	W	Hypothetical protein
10834	S000002502	ORF	Dubious	YDR095C	n.a.	4	636522	636112	C	Hypothetical protein
10836	S000002503	ORF	Verified	YDR096W	GIS1	4	637134	639818	W	Transcriptional factor, involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1
10838	S000002504	ORF	Verified	YDR097C	MSH6	4	643832	640104	C	Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p
10840	S000002505	ORF	Verified	YDR098C	GRX3	4	645030	644173	C	Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage
10842	S000006694	tRNA	n.a.	tQ(UUG)D2	n.a.	4	645219	645148	C	tRNA-Gln
10855	S000002506	ORF	Verified	YDR099W	BMH2	4	653602	654423	W	14-3-3 protein, minor isoform; binds proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras/MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling, and others
10857	S000002507	ORF	Uncharacterized	YDR100W	n.a.	4	655008	655439	W	Tlg2-Vesicle Protein of 15 kDa; integral membrane vesicle protein
10859	S000002508	ORF	Verified	YDR101C	ARX1	4	657462	655681	C	Protein associated with the ribosomal export complex
10861	S000002509	ORF	Dubious	YDR102C	n.a.	4	657975	657643	C	Hypothetical protein
10863	S000002510	ORF	Verified	YDR103W	STE5	4	658345	661098	W	Scaffold protein that, in response to pheromone, shuttles from the nucleus to the plasma membrane and assembles kinases Ste11p, Ste7p, and Fus3p into a specific signaling complex; active oligomeric form interacts with Ste4p-Ste18p complex
10865	S000002511	ORF	Verified	YDR104C	SPO71	4	664905	661168	C	Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis
10867	S000002512	ORF	Verified	YDR105C	TMS1	4	666765	665344	C	Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance
10869	S000002513	ORF	Verified	YDR106W	ARP10	4	666999	667853	W	Actin-related protein
10871	S000006601	tRNA	n.a.	tI(AAU)D	n.a.	4	668075	668002	C	tRNA-Ile
10875	S000002514	ORF	Uncharacterized	YDR107C	n.a.	4	671029	669011	C	multispanning membrane protein
10877	S000002515	ORF	Verified	YDR108W	GSG1	4	671264	673360	W	Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication
10879	S000002516	ORF	Uncharacterized	YDR109C	n.a.	4	675662	673515	C	Hypothetical protein
10881	S000002517	ORF	Verified	YDR110W	FOB1	4	676097	677797	W	Nucleolar protein required for DNA replication fork blocking and recombinational hotspot activities; binds to the replication fork barrier site in the rDNA region; related to retroviral integrases
10883	S000002519	ORF	Dubious	YDR112W	n.a.	4	679539	679847	W	Hypothetical protein
10885	S000002518	ORF	Uncharacterized	YDR111C	n.a.	4	679759	678236	C	Putative alanine transaminase (glutamic pyruvic transaminase)
10887	S000002520	ORF	Verified	YDR113C	PDS1	4	681612	680491	C	Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei
10889	S000002522	ORF	Verified	YDR115W	n.a.	4	682170	682487	W	Putative mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L34 ribosomal protein; required for respiratory growth, as are most mitochondrial ribosomal proteins
10891	S000002521	ORF	Dubious	YDR114C	n.a.	4	682221	681919	C	Hypothetical protein
10893	S000002523	ORF	Verified	YDR116C	MRPL1	4	683576	682719	C	Mitochondrial ribosomal protein of the large subunit
10895	S000002524	ORF	Uncharacterized	YDR117C	n.a.	4	685638	683941	C	Hypothetical protein
10897	S000002525	ORF	Verified	YDR118W	APC4	4	685877	687835	W	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
10899	S000028820	ORF	Dubious	YDR118W-A	n.a.	4	687763	687879	W	Identified by expression profiling and mass spectrometry
10901	S000002526	ORF	Uncharacterized	YDR119W	n.a.	4	688222	690528	W	Hypothetical protein
10903	S000002527	ORF	Verified	YDR120C	TRM1	4	693256	691544	C	tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments
10905	S000002528	ORF	Verified	YDR121W	DPB4	4	693580	694170	W	Shared subunit of DNA polymerase epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing
10907	S000002529	ORF	Verified	YDR122W	KIN1	4	694695	697889	W	Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p
10909	S000002530	ORF	Verified	YDR123C	INO2	4	699463	698549	C	Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion
10911	S000002531	ORF	Uncharacterized	YDR124W	n.a.	4	700310	701284	W	Hypothetical protein
10913	S000002532	ORF	Verified	YDR125C	ECM18	4	702753	701392	C	Protein of unknown function, similar to Rlp24p
10915	S000002533	ORF	Verified	YDR126W	SWF1	4	703229	704239	W	Protein essential for spore wall formation
10917	S000002534	ORF	Verified	YDR127W	ARO1	4	704479	709245	W	Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids
10919	S000002535	ORF	Uncharacterized	YDR128W	n.a.	4	709544	712990	W	Hypothetical protein
10921	S000002536	ORF	Verified	YDR129C	SAC6	4	715374	713335	C	Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton
10924	S000030259	intron	n.a.	n.a.	n.a.	4	715353	715243	C	n.a.
10925	S000002537	ORF	Verified	YDR130C	FIN1	4	716617	715742	C	Basic protein with putative coiled-coil regions that comprises a filament between spindle pole bodies; self-assembles into filaments with a diameter of approximately 10 nm; potential Cdc28p substrate
10927	S000002538	ORF	Uncharacterized	YDR131C	n.a.	4	718455	716785	C	Hypothetical protein
10929	S000002539	ORF	Uncharacterized	YDR132C	n.a.	4	720298	718811	C	Hypothetical protein
10931	S000002540	ORF	Dubious	YDR133C	n.a.	4	721292	720957	C	Hypothetical protein
10935	S000002542	ORF	Verified	YDR135C	YCF1	4	727546	722999	C	Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR
10937	S000002544	ORF	Verified	YDR137W	RGP1	4	728254	730245	W	Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p
10939	S000002543	ORF	Dubious	YDR136C	VPS61	4	728278	727706	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 4% of ORF overlaps the verified gene RGP1; deletion causes a vacuolar protein sorting defect
10941	S000002545	ORF	Verified	YDR138W	HPR1	4	730573	732831	W	Subunit of THO/TREX, related complexes that couple transcription elongation with mitotic recombination and elongation with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; similar to Top1p
10943	S000002546	ORF	Verified	YDR139C	RUB1	4	733919	733613	C	Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)
10946	S000033099	intron	n.a.	n.a.	n.a.	4	733770	733698	C	n.a.
10947	S000002547	ORF	Uncharacterized	YDR140W	n.a.	4	734133	734798	W	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; methylates release factor eRF1 (Sup45p) in vitro
10949	S000002548	ORF	Verified	YDR141C	DOP1	4	739992	734896	C	Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
10951	S000002549	ORF	Verified	YDR142C	PEX7	4	741595	740468	C	Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP)
10953	S000002550	ORF	Verified	YDR143C	SAN1	4	743869	742037	C	Ubiquitin-protein ligase, controls turnover of a specific class of unstable nuclear proteins including Sir4p but not Sir2p or Sir3p; san1 mutations suppress sir4, spt16, and cdc68 mutations, suggesting a role in chromatin silencing
10955	S000002551	ORF	Verified	YDR144C	MKC7	4	746096	744306	C	GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p
10957	S000002552	ORF	Verified	YDR145W	TAF12	4	746733	748352	W	Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A
10959	S000002553	ORF	Verified	YDR146C	SWI5	4	750737	748608	C	Transcription factor that activates transcription of genes expressed in G1 phase and at the G1/M boundary; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase
10961	S000002554	ORF	Verified	YDR147W	EKI1	4	751626	753230	W	Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; also exhibits choline kinase activity
10963	S000002555	ORF	Verified	YDR148C	KGD2	4	755061	753670	C	Dihydrolipoyl transsuccinylase, a component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA
10965	S000002557	ORF	Verified	YDR150W	NUM1	4	755623	763869	W	Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex
10967	S000002556	ORF	Dubious	YDR149C	n.a.	4	756257	755550	C	Hypothetical protein
10969	S000002558	ORF	Verified	YDR151C	CTH1	4	765150	764173	C	Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis
10971	S000002559	ORF	Verified	YDR152W	GIR2	4	765701	766498	W	Highly-acidic cytoplasmic RWD domain-containing protein of unknown function, sensitive to proteolysis, N-terminal region has high content of acidic amino acid residues, putative IUP (intrinsically unstructured protein)
10973	S000002560	ORF	Verified	YDR153C	ENT5	4	767966	766731	C	Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin
10975	S000002561	ORF	Dubious	YDR154C	n.a.	4	768748	768398	C	Hypothetical protein
10977	S000002562	ORF	Verified	YDR155C	CPR1	4	768995	768507	C	Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A
10979	S000002563	ORF	Verified	YDR156W	RPA14	4	769520	769933	W	RNA polymerase I subunit A14
10981	S000002564	ORF	Dubious	YDR157W	n.a.	4	769926	770327	W	Hypothetical protein
10983	S000002565	ORF	Verified	YDR158W	HOM2	4	770352	771449	W	Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis
10985	S000002566	ORF	Verified	YDR159W	SAC3	4	771872	775777	W	Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus
10987	S000002567	ORF	Verified	YDR160W	SSY1	4	776158	778716	W	Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
10989	S000002568	ORF	Uncharacterized	YDR161W	n.a.	4	779038	780201	W	interacts with PP2C
10991	S000002569	ORF	Verified	YDR162C	NBP2	4	781095	780385	C	Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p
10993	S000002570	ORF	Verified	YDR163W	CWC15	4	781418	781945	W	Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p
10995	S000002571	ORF	Verified	YDR164C	SEC1	4	784210	782036	C	Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function
10997	S000002572	ORF	Verified	YDR165W	TRM82	4	784866	786200	W	Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA
10999	S000002573	ORF	Verified	YDR166C	SEC5	4	789216	786301	C	Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
11001	S000002574	ORF	Verified	YDR167W	TAF10	4	789444	790064	W	Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification
11003	S000002575	ORF	Verified	YDR168W	CDC37	4	790323	791843	W	Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle
11005	S000002576	ORF	Verified	YDR169C	STB3	4	793884	792343	C	Protein that binds Sin3p in a two-hybrid assay
11007	S000028538	ORF	Uncharacterized	YDR169C-A	n.a.	4	794718	794569	C	Identified by fungal homology and RT-PCR
11009	S000002577	ORF	Verified	YDR170C	SEC7	4	802217	796188	C	Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles
11011	S000006695	tRNA	n.a.	tQ(UUG)D3	n.a.	4	802797	802726	C	tRNA-Gln
11016	S000002578	ORF	Verified	YDR171W	HSP42	4	806616	807743	W	Small cytosolic stress-induced chaperone that forms barrel-shaped oligomers and suppresses the aggregation of non-native proteins; oligomer dissociation is not required for function; involved in cytoskeleton reorganization after heat shock
11018	S000002579	ORF	Verified	YDR172W	SUP35	4	808319	810376	W	Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonsense suppressor phenotype
11020	S000002580	ORF	Verified	YDR173C	ARG82	4	811627	810560	C	Protein involved in regulation of arginine-responsive and Mcm1p-dependent genes; has a dual-specificity inositol polyphosphate kinase activity required for regulation of phosphate- and nitrogen-responsive genes
11022	S000002581	ORF	Verified	YDR174W	HMO1	4	812105	812845	W	Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase
11024	S000002582	ORF	Verified	YDR175C	RSM24	4	814147	813188	C	Mitochondrial ribosomal protein of the small subunit
11026	S000002583	ORF	Verified	YDR176W	NGG1	4	814447	816555	W	Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex
11028	S000002584	ORF	Verified	YDR177W	UBC1	4	816873	817520	W	Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response
11030	S000002585	ORF	Verified	YDR178W	SDH4	4	817945	818490	W	Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone
11032	S000002586	ORF	Verified	YDR179C	CSN9	4	819191	818703	C	Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling
11034	S000002587	ORF	Uncharacterized	YDR179W-A	n.a.	4	819428	820819	W	Hypothetical protein
11036	S000002588	ORF	Verified	YDR180W	SCC2	4	821290	825771	W	Putative protein kinase and subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX
11038	S000002589	ORF	Verified	YDR181C	SAS4	4	827350	825905	C	Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which  acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p
11040	S000002590	ORF	Verified	YDR182W	CDC1	4	827577	829052	W	Putative membrane protein of unknown function involved in Mn2+ homeostasis; mutants display actin and general growth defects, heterogeneous cell cycle arrests, and pleiotropic defects in cell cycle progression and organelle distribution
11042	S000028539	ORF	Uncharacterized	YDR182W-A	n.a.	4	829146	829349	W	Identified by fungal homology and RT-PCR
11044	S000002591	ORF	Verified	YDR183W	PLP1	4	829580	830272	W	Protein with a possible role in folding of beta-tubulin; has similarity to phosducins, which are GTPase inhibitors
11046	S000028540	ORF	Dubious	YDR183C-A	n.a.	4	830649	830392	C	Identified by fungal homology and RT-PCR
11048	S000002592	ORF	Verified	YDR184C	ATC1	4	831508	830624	C	Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern
11050	S000002593	ORF	Uncharacterized	YDR185C	n.a.	4	832468	831929	C	Hypothetical protein
11052	S000002594	ORF	Uncharacterized	YDR186C	n.a.	4	835487	832854	C	Hypothetical protein
11054	S000002596	ORF	Verified	YDR188W	CCT6	4	836416	838056	W	Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif
11056	S000002595	ORF	Dubious	YDR187C	n.a.	4	836741	836223	C	Protein required for cell viability
11058	S000002597	ORF	Verified	YDR189W	SLY1	4	838387	840387	W	Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex
11060	S000002598	ORF	Verified	YDR190C	RVB1	4	841990	840599	C	Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family
11062	S000002599	ORF	Verified	YDR191W	HST4	4	842332	843444	W	Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism
11064	S000002601	ORF	Dubious	YDR193W	n.a.	4	844549	844947	W	Hypothetical protein
11066	S000002600	ORF	Verified	YDR192C	NUP42	4	844856	843564	C	Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side; involved in RNA export, most likely at a terminal step; interacts with Gle1p
11068	S000002602	ORF	Verified	YDR194C	MSS116	4	847941	845947	C	DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; presumed RNA helicase due to DEAD-box motif
11070	S000028541	ORF	Uncharacterized	YDR194W-A	n.a.	4	848066	848218	W	Identified by fungal homology and RT-PCR
11072	S000002603	ORF	Verified	YDR195W	REF2	4	848594	850195	W	RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation; also involved in snoRNA maturation
11074	S000002604	ORF	Uncharacterized	YDR196C	n.a.	4	850994	850269	C	predicted to catalyze the final step in synthesis of Coenzyme A
11076	S000002605	ORF	Verified	YDR197W	CBS2	4	851223	852392	W	Translational activator of COB mRNA; soluble protein; cytochrome b translational activator
11078	S000002606	ORF	Uncharacterized	YDR198C	n.a.	4	853967	852528	C	Hypothetical protein
11080	S000002607	ORF	Dubious	YDR199W	n.a.	4	854170	854535	W	Hypothetical protein
11082	S000002608	ORF	Verified	YDR200C	VPS64	4	856088	854274	C	Cytoplasmic protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p, Far7p, Far10p, and Far11p that is involved in pheromone-induced cell cycle arrest; also localized to the endoplasmic reticulum membrane
11084	S000002609	ORF	Verified	YDR201W	SPC19	4	856312	856809	W	Component of Dam1p complex, important for spindle and kinetochore integrity; localized to nuclear side of spindle pole body and along mitotic spindle
11086	S000002611	ORF	Dubious	YDR203W	n.a.	4	857677	857994	W	Hypothetical protein
11088	S000002610	ORF	Verified	YDR202C	RAV2	4	857948	856893	C	Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme
11090	S000002612	ORF	Verified	YDR204W	COQ4	4	858132	859139	W	Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex
11092	S000002613	ORF	Verified	YDR205W	MSC2	4	859341	861515	W	Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids
11094	S000002614	ORF	Verified	YDR206W	EBS1	4	862049	864703	W	Protein of unknown function, contains a putative RNA recognition motif, deletion results in short telomeres; similar to Est1p, may be partially redundant with Est1p for telomere maintenance
11096	S000002615	ORF	Verified	YDR207C	UME6	4	867517	865007	C	Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p
11098	S000002616	ORF	Verified	YDR208W	MSS4	4	868219	870558	W	Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation
11100	S000002618	ORF	Uncharacterized	YDR210W	n.a.	4	871069	871296	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
11102	S000002617	ORF	Dubious	YDR209C	n.a.	4	871444	871031	C	Hypothetical protein
11120	S000006613	tRNA	n.a.	tI(UAU)D	n.a.	4	884356	884488	W	tRNA-Ile
11121	S000035113	intron	n.a.	n.a.	n.a.	4	884393	884452	W	n.a.
11124	S000002619	ORF	Verified	YDR211W	GCD6	4	884722	886860	W	Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression
11126	S000002620	ORF	Verified	YDR212W	TCP1	4	887227	888906	W	Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in maintenance of actin cytoskeleton; homolog to Drosophila melanogaster and mouse tailless complex polypeptide
11128	S000002621	ORF	Verified	YDR213W	UPC2	4	889746	892487	W	Sterol regulatory element binding protein, induces transcription of sterol transport and biosynthetic genes; involved in the anaerobic induction of DAN/TIR mannoproteins and seripauperins; binucleate zinc cluster protein; Ecm22p homolog
11130	S000002622	ORF	Verified	YDR214W	AHA1	4	892870	893922	W	Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock
11132	S000002623	ORF	Dubious	YDR215C	n.a.	4	894496	894113	C	Hypothetical protein
11134	S000002624	ORF	Verified	YDR216W	ADR1	4	895029	899000	W	Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization
11136	S000002625	ORF	Verified	YDR217C	RAD9	4	903474	899545	C	DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate
11138	S000002626	ORF	Verified	YDR218C	SPR28	4	905046	903775	C	Septin-related protein expressed during sporulation
11140	S000002627	ORF	Uncharacterized	YDR219C	n.a.	4	906846	905449	C	Hypothetical protein
11142	S000002628	ORF	Dubious	YDR220C	n.a.	4	907287	906994	C	Hypothetical protein
11144	S000002629	ORF	Uncharacterized	YDR221W	n.a.	4	907324	909432	W	Hypothetical protein
11146	S000002630	ORF	Uncharacterized	YDR222W	n.a.	4	910048	911295	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
11148	S000002631	ORF	Verified	YDR223W	CRF1	4	912093	913496	W	Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus
11150	S000002632	ORF	Verified	YDR224C	HTB1	4	914706	914311	C	One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation
11152	S000002633	ORF	Verified	YDR225W	HTA1	4	915524	915922	W	One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p
11154	S000002634	ORF	Verified	YDR226W	ADK1	4	916480	917148	W	Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence
11156	S000002635	ORF	Verified	YDR227W	SIR4	4	917565	921641	W	Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan
11158	S000002636	ORF	Verified	YDR228C	PCF11	4	923800	921920	C	mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)
11160	S000002637	ORF	Verified	YDR229W	IVY1	4	924779	926140	W	Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase
11162	S000002638	ORF	Dubious	YDR230W	n.a.	4	926217	926564	W	Hypothetical protein
11164	S000002639	ORF	Verified	YDR231C	COX20	4	926904	926287	C	Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase
11166	S000002640	ORF	Verified	YDR232W	HEM1	4	927446	929092	W	5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p
11168	S000002641	ORF	Verified	YDR233C	RTN1	4	930351	929464	C	Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily
11170	S000002642	ORF	Verified	YDR234W	LYS4	4	931123	933204	W	Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway
11172	S000002643	ORF	Verified	YDR235W	PRP42	4	933498	935132	W	U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats
11174	S000002644	ORF	Verified	YDR236C	FMN1	4	935886	935230	C	Riboflavin kinase, phosphorylates riboflavin to form riboflavin monophosphate (FMN), which is a necessary cofactor for many enzymes; localizes to microsomes and to the mitochondrial inner membrane
11176	S000002645	ORF	Verified	YDR237W	MRPL7	4	936609	937487	W	Mitochondrial ribosomal protein of the large subunit
11178	S000002646	ORF	Verified	YDR238C	SEC26	4	940810	937889	C	Essential subunit of the COP II vesicle coat, involved in endoplasmic-to-Golgi protein trafficking and maintenance of normal ER morphology; similar to mammalian beta-coat protein (beta-COP)
11180	S000002647	ORF	Uncharacterized	YDR239C	n.a.	4	943414	941051	C	Hypothetical protein
11182	S000002649	ORF	Dubious	YDR241W	BUD26	4	945145	945432	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 1% of ORF overlaps the verified gene SNU56; diploid mutant displays a weak budding pattern phenotype in a systematic assay
11184	S000002648	ORF	Verified	YDR240C	SNU56	4	945146	943668	C	U1 snRNP protein, serine-rich; has no counterpart in mammalian U1 snRNP
11188	S000006778	tRNA	n.a.	tY(GUA)D	SUP2	4	946306	946394	W	tRNA-Tyr
11189	S000034661	intron	n.a.	n.a.	n.a.	4	946345	946358	W	n.a.
11192	S000002650	ORF	Verified	YDR242W	AMD2	4	946801	948450	W	Putative amidase
11194	S000002651	ORF	Verified	YDR243C	PRP28	4	950278	948512	C	RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site
11196	S000002652	ORF	Verified	YDR244W	PEX5	4	950557	952395	W	Peroxisomal membrane signal receptor for C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import, tetratricopeptide repeat protein, also involved in PTS1-independent import
11198	S000002653	ORF	Verified	YDR245W	MNN10	4	952794	953975	W	Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family
11200	S000002654	ORF	Verified	YDR246W	TRS23	4	954282	954941	W	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic; human homolog is TRAPPC4
11202	S000028542	ORF	Uncharacterized	YDR246W-A	n.a.	4	955127	955327	W	Identified by fungal homology and RT-PCR
11204	S000002655	ORF	Verified	YDR247W	VHS1	4	956007	957392	W	Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p
11206	S000002656	ORF	Uncharacterized	YDR248C	n.a.	4	958333	957752	C	Hypothetical protein
11208	S000002657	ORF	Uncharacterized	YDR249C	n.a.	4	959796	958675	C	Hypothetical protein
11210	S000002658	ORF	Dubious	YDR250C	n.a.	4	960355	960080	C	Hypothetical protein
11212	S000002659	ORF	Verified	YDR251W	PAM1	4	960608	963100	W	Essential protein of unknown function; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype
11214	S000002660	ORF	Verified	YDR252W	BTT1	4	963406	963855	W	Beta3 subunit of the heterotrimeric nascent polypeptide-associated complex (alpha, beta1, beta3) which binds ribosomes via its beta-subunits in close proximity to nascent polypeptides
11216	S000002661	ORF	Verified	YDR253C	MET32	4	964559	963984	C	Zinc-finger DNA-binding protein, involved in regulating expression of the methionine biosynthetic genes, similar to Met31p
11218	S000002662	ORF	Verified	YDR254W	CHL4	4	965107	966483	W	Outer kinetochore protein required for chromosome stability, interacts with kinetochore proteins Ctf19p, Ctf3p, and Iml3p; exhibits a two-hybrid interaction with Mif2p; association with CEN DNA requires Ctf19p
11220	S000002663	ORF	Verified	YDR255C	RMD5	4	967816	966551	C	Cytosolic protein required for sporulation; also required for the ubiquitination of the gluconeogenetic enzyme fructose-1,6-bisphosphatase, which is degraded rapidly after the switch from gluconeogenesis to glycolysis
11222	S000002664	ORF	Verified	YDR256C	CTA1	4	969674	968127	C	Catalase A, breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation
11224	S000002665	ORF	Verified	YDR257C	SET7	4	971468	969984	C	Nuclear protein that contains a SET-domain, which have been shown to mediate methyltransferase activity in other proteins
11226	S000002666	ORF	Verified	YDR258C	HSP78	4	974237	971802	C	Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system
11228	S000002667	ORF	Verified	YDR259C	YAP6	4	975776	974625	C	Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance
11230	S000002668	ORF	Verified	YDR260C	SWM1	4	977223	976711	C	Subunit of the anaphase-promoting complex, which is an E3 ubiquitin ligase that regulates the metaphase-anaphase transition and exit from mitosis; required for activation of the daughter-specific gene expression and spore wall maturation
11232	S000002669	ORF	Verified	YDR261C	EXG2	4	979203	977515	C	Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor
11234	S000006722	tRNA	n.a.	tS(AGA)D2	n.a.	4	981049	980968	C	tRNA-Ser
11255	S000006577	tRNA	n.a.	tG(GCC)D2	n.a.	4	992826	992896	W	tRNA-Gly
11257	S000002670	ORF	Uncharacterized	YDR262W	n.a.	4	993128	993946	W	Hypothetical protein
11259	S000002671	ORF	Verified	YDR263C	DIN7	4	995528	994236	C	Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination
11261	S000002672	ORF	Verified	YDR264C	AKR1	4	998317	996023	C	Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats
11263	S000002673	ORF	Verified	YDR265W	PEX10	4	998858	999871	W	RING finger peroxisomal membrane peroxin required for peroxisomal matrix protein import, interacts with Pex12p, links ubiquitin-conjugating Pex4p to protein import machinery; mutations in human homolog cause a variety of peroxisomal disorders
11265	S000002674	ORF	Uncharacterized	YDR266C	n.a.	4	1002017	1000098	C	Hypothetical protein
11267	S000002675	ORF	Uncharacterized	YDR267C	n.a.	4	1003496	1002504	C	Essential protein involved in assembly of cytosolic and nuclear iron-sulfur proteins
11269	S000002676	ORF	Verified	YDR268W	MSW1	4	1003998	1005137	W	Mitochondrial tryptophanyl-tRNA synthetase
11271	S000002678	ORF	Verified	YDR270W	CCC2	4	1005669	1008683	W	copper-transporting P-type ATPase with similarity to human Menkes and Wilsons genes; Cu(2+)-transporting ATPase
11273	S000002677	ORF	Dubious	YDR269C	n.a.	4	1005982	1005659	C	Hypothetical protein
11275	S000002679	ORF	Dubious	YDR271C	n.a.	4	1008760	1008389	C	Hypothetical protein
11277	S000002680	ORF	Verified	YDR272W	GLO2	4	1009004	1009828	W	Cytoplasmic glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate
11279	S000002681	ORF	Verified	YDR273W	DON1	4	1010170	1011267	W	Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II
11281	S000002682	ORF	Dubious	YDR274C	n.a.	4	1011954	1011583	C	Hypothetical protein
11283	S000002683	ORF	Verified	YDR275W	BSC2	4	1012246	1012953	W	Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression
11285	S000002684	ORF	Verified	YDR276C	PMP3	4	1013637	1013470	C	Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential
11287	S000002685	ORF	Verified	YDR277C	MTH1	4	1015696	1014395	C	Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation
11289	S000006546	tRNA	n.a.	tE(CUC)D	n.a.	4	1017272	1017201	C	tRNA-Glu
11291	S000002686	ORF	Dubious	YDR278C	n.a.	4	1017312	1016995	C	Hypothetical protein
11293	S000002687	ORF	Verified	YDR279W	RNH202	4	1019362	1020414	W	Ribonuclease H2 subunit, required for RNase H2 activity
11295	S000002688	ORF	Verified	YDR280W	RRP45	4	1020741	1021658	W	Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex
11297	S000002689	ORF	Verified	YDR281C	PHM6	4	1022315	1022001	C	Protein of unknown function, expression is regulated by phosphate levels
11300	S000002690	ORF	Uncharacterized	YDR282C	n.a.	4	1024749	1023505	C	Hypothetical protein
11302	S000002691	ORF	Verified	YDR283C	GCN2	4	1030043	1025064	C	Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex
11304	S000002692	ORF	Verified	YDR284C	DPP1	4	1031413	1030544	C	Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism
11306	S000002693	ORF	Verified	YDR285W	ZIP1	4	1032430	1035057	W	Synaptonemal complex (SC) protein that connects homologous chromosomes partially during zygotene and entirely during pachytene; potential Cdc28p substrate; synaptonemal complex protein
11308	S000002694	ORF	Uncharacterized	YDR286C	n.a.	4	1035569	1035225	C	Hypothetical protein
11310	S000002695	ORF	Uncharacterized	YDR287W	n.a.	4	1035989	1036867	W	<u>in</U>ositol <u>m</U>onophosphatase
11312	S000002696	ORF	Uncharacterized	YDR288W	NSE3	4	1037189	1038100	W	Essential protein of unknown function; interacts with Nse4p, which is a component of the Smc5/6 DNA repair complex
11314	S000002698	ORF	Dubious	YDR290W	n.a.	4	1039364	1039693	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 42% of ORF overlaps the verified gene RTT103; deletion causes hydroxyuracil sensitivity
11316	S000002697	ORF	Verified	YDR289C	RTT103	4	1039503	1038274	C	Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in transcription termination by RNA polymerase II, has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition
11318	S000002699	ORF	Uncharacterized	YDR291W	n.a.	4	1039722	1042955	W	Hypothetical protein
11320	S000002700	ORF	Verified	YDR292C	SRP101	4	1045005	1043140	C	Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with SRP102p
11322	S000002701	ORF	Verified	YDR293C	SSD1	4	1049386	1045634	C	Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence
11324	S000002702	ORF	Verified	YDR294C	DPL1	4	1052222	1050453	C	Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate
11326	S000002703	ORF	Verified	YDR295C	HDA2	4	1054641	1052617	C	Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda3p; Ploidy-related
11328	S000002704	ORF	Verified	YDR296W	MHR1	4	1055206	1055886	W	Protein involved in homologous recombination in mitochondria and in transcription regulation in nucleus; binds to activation domains of acidic activators; required for recombination-dependent mtDNA partitioning
11330	S000002705	ORF	Verified	YDR297W	SUR2	4	1056545	1057594	W	Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis
11332	S000002706	ORF	Verified	YDR298C	ATP5	4	1058808	1058170	C	Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein)
11334	S000002707	ORF	Verified	YDR299W	BFR2	4	1059621	1061225	W	Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A
11336	S000002708	ORF	Verified	YDR300C	PRO1	4	1062785	1061499	C	Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis
11338	S000002709	ORF	Verified	YDR301W	CFT1	4	1063346	1067419	W	RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF
11340	S000002710	ORF	Verified	YDR302W	GPI11	4	1067725	1068384	W	ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI) anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated GPI intermediate; human PIG-Fp is a functional homolog
11342	S000002711	ORF	Verified	YDR303C	RSC3	4	1071380	1068723	C	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p
11344	S000002712	ORF	Verified	YDR304C	CPR5	4	1072551	1071874	C	Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER
11346	S000002713	ORF	Verified	YDR305C	HNT2	4	1073482	1072740	C	Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins
11349	S000034248	intron	n.a.	n.a.	n.a.	4	1073395	1073307	C	n.a.
11350	S000002714	ORF	Uncharacterized	YDR306C	n.a.	4	1075165	1073729	C	Hypothetical protein
11352	S000006767	tRNA	n.a.	tV(CAC)D	n.a.	4	1075538	1075466	C	tRNA-Val
11354	S000002715	ORF	Uncharacterized	YDR307W	n.a.	4	1075859	1077847	W	Hypothetical protein
11356	S000002716	ORF	Verified	YDR308C	SRB7	4	1078443	1078021	C	RNA polymerase II holoenzyme component
11358	S000002717	ORF	Verified	YDR309C	GIC2	4	1080193	1079042	C	Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain
11360	S000002718	ORF	Verified	YDR310C	SUM1	4	1084310	1081122	C	Transcriptional repressor required for repression of middle sporulation-specific genes during mitosis; regulated by the pachytene checkpoint; a dominant mutation acts as a suppressor of silencing defects of SIR2 mutations
11362	S000002719	ORF	Verified	YDR311W	TFB1	4	1085060	1086988	W	Subunit of TFIIH and nucleotide excision repair factor 3 complexes, required for nucleotide excision repair, target for transcriptional activators
11364	S000002720	ORF	Verified	YDR312W	SSF2	4	1087576	1088937	W	Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member of the Brix family
11366	S000002721	ORF	Verified	YDR313C	PIB1	4	1090074	1089214	C	RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain
11368	S000002722	ORF	Uncharacterized	YDR314C	n.a.	4	1092506	1090428	C	Hypothetical protein
11370	S000002723	ORF	Verified	YDR315C	IPK1	4	1093581	1092736	C	Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable
11372	S000002724	ORF	Verified	YDR316W	OMS1	4	1093758	1095173	W	Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations
11374	S000006563	tRNA	n.a.	tF(GAA)D	n.a.	4	1095456	1095365	C	tRNA-Phe
11375	S000035376	intron	n.a.	n.a.	n.a.	4	1095419	1095401	C	n.a.
11387	S000002725	ORF	Verified	YDR317W	HIM1	4	1102179	1103423	W	Protein of unknown function involved in DNA repair
11389	S000002726	ORF	Verified	YDR318W	MCM21	4	1103753	1104942	W	Protein involved in minichromosome maintenance; component of the COMA complex that bridges kinetochore subunits that are in contact with centromeric DNA and the subunits bound to microtubules
11392	S000030338	intron	n.a.	n.a.	n.a.	4	1103805	1103887	W	n.a.
11393	S000002727	ORF	Uncharacterized	YDR319C	n.a.	4	1105822	1104998	C	Hypothetical protein
11395	S000002728	ORF	Verified	YDR320C	SWA2	4	1108096	1106090	C	Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles
11397	S000028821	ORF	Dubious	YDR320W-B	n.a.	4	1108479	1108616	W	Identified by expression profiling and mass spectrometry
11399	S000007604	ORF	Verified	YDR320C-A	DAD4	4	1108493	1108275	C	Essential protein, component of the DASH complex; involved in spindle integrity and kinetochore function; interacts with Duo1p and Dam1p; localizes to intranuclear spindles and kinetochore
11401	S000002729	ORF	Verified	YDR321W	ASP1	4	1108697	1109842	W	Cytosolic L-asparaginase, involved in asparagine catabolism
11403	S000002730	ORF	Verified	YDR322W	MRPL35	4	1110584	1111687	W	Mitochondrial ribosomal protein of the large subunit
11405	S000007255	ORF	Verified	YDR322C-A	TIM11	4	1112288	1111998	C	Subunit e of mitochondrial F1F0-ATPase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric state of ATP synthase
11407	S000002731	ORF	Verified	YDR323C	PEP7	4	1114022	1112475	C	Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance
11409	S000002732	ORF	Verified	YDR324C	UTP4	4	1116758	1114428	C	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
11411	S000002733	ORF	Verified	YDR325W	YCG1	4	1117119	1120226	W	Yeast Condensin G
11413	S000002734	ORF	Uncharacterized	YDR326C	n.a.	4	1124918	1120602	C	Hypothetical protein
11415	S000002735	ORF	Dubious	YDR327W	n.a.	4	1125295	1125621	W	Protein required for cell viability
11417	S000002736	ORF	Verified	YDR328C	SKP1	4	1126011	1125427	C	Evolutionarily conserved kinetochore protein that is part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase
11419	S000002737	ORF	Verified	YDR329C	PEX3	4	1127588	1126263	C	Peroxisomal membrane protein (PMP) required to recruit Pex19p chaperone to peroxisomes; plays selective, essential, direct role in PMP import as a docking factor for Pex19p
11421	S000002738	ORF	Uncharacterized	YDR330W	UBX5	4	1127865	1129367	W	UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p
11423	S000002739	ORF	Verified	YDR331W	GPI8	4	1129581	1130816	W	ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog
11425	S000002740	ORF	Uncharacterized	YDR332W	n.a.	4	1130994	1133063	W	Hypothetical protein
11427	S000002741	ORF	Uncharacterized	YDR333C	n.a.	4	1135424	1133253	C	Hypothetical protein
11429	S000002742	ORF	Verified	YDR334W	SWR1	4	1135925	1140469	W	Swi2/Snf2-related ATPase, component of the SWR1 complex; required for the incorporation of Htz1p into chromatin
11431	S000002743	ORF	Verified	YDR335W	MSN5	4	1141160	1144834	W	Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP
11433	S000002744	ORF	Uncharacterized	YDR336W	n.a.	4	1145084	1146028	W	Hypothetical protein
11435	S000002745	ORF	Verified	YDR337W	MRPS28	4	1146311	1147171	W	Mitochondrial ribosomal protein of the small subunit
11437	S000002746	ORF	Uncharacterized	YDR338C	n.a.	4	1149458	1147371	C	Hypothetical protein
11439	S000002747	ORF	Uncharacterized	YDR339C	n.a.	4	1150512	1149943	C	Protein required for cell viability
11441	S000002748	ORF	Dubious	YDR340W	n.a.	4	1150873	1151175	W	Hypothetical protein
11443	S000006777	tRNA	n.a.	tX(n.a.)D	n.a.	4	1150933	1150834	C	tRNA-Undet
11446	S000002749	ORF	Verified	YDR341C	n.a.	4	1153618	1151795	C	Cytoplasmic arginyl-tRNA synthetase
11448	S000002750	ORF	Verified	YDR342C	HXT7	4	1155920	1154208	C	High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels
11450	S000002751	ORF	Verified	YDR343C	HXT6	4	1161312	1159600	C	High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3
11452	S000002752	ORF	Dubious	YDR344C	n.a.	4	1162441	1161998	C	Hypothetical protein
11454	S000002753	ORF	Verified	YDR345C	HXT3	4	1164652	1162949	C	Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions
11456	S000002754	ORF	Verified	YDR346C	SVF1	4	1168651	1167206	C	Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis
11458	S000002755	ORF	Verified	YDR347W	MRP1	4	1169170	1170135	W	Mitochondrial ribosomal protein of the small subunit; MRP1 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator, and with PET123, encoding a small subunit mitochondrial ribosomal protein
11460	S000002756	ORF	Uncharacterized	YDR348C	n.a.	4	1171817	1170318	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate
11462	S000002757	ORF	Verified	YDR349C	YPS7	4	1174168	1172378	C	Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmic reticulum
11466	S000006659	tRNA	n.a.	tM(CAU)D	EMT1	4	1175821	1175893	W	tRNA that accepts methionine; functions in translational elongation but not translational initiation
11468	S000002758	ORF	Verified	YDR350C	TCM10	4	1178165	1176330	C	Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
11470	S000002759	ORF	Verified	YDR351W	SBE2	4	1178657	1181251	W	Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth
11472	S000002760	ORF	Uncharacterized	YDR352W	n.a.	4	1181792	1182745	W	Hypothetical protein
11474	S000002761	ORF	Verified	YDR353W	TRR1	4	1183290	1184249	W	Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress
11476	S000002762	ORF	Verified	YDR354W	TRP4	4	1184738	1185880	W	Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis
11478	S000028613	ORF	Dubious	YDR354C-A	n.a.	4	1185273	1185130	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11480	S000002764	ORF	Verified	YDR356W	SPC110	4	1186098	1188932	W	Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner
11482	S000002763	ORF	Dubious	YDR355C	n.a.	4	1186360	1186058	C	Protein required for cell viability
11484	S000002765	ORF	Uncharacterized	YDR357C	n.a.	4	1189558	1189190	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
11486	S000002766	ORF	Verified	YDR358W	GGA1	4	1190050	1191723	W	Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi
11488	S000002768	ORF	Dubious	YDR360W	n.a.	4	1194589	1194975	W	Hypothetical protein
11490	S000002767	ORF	Verified	YDR359C	VID21	4	1194875	1191927	C	Component of the NuA4 histone acetyltransferase complex
11492	S000002769	ORF	Uncharacterized	YDR361C	BCP1	4	1196253	1195402	C	Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport
11494	S000002770	ORF	Verified	YDR362C	TFC6	4	1198687	1196669	C	One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110
11496	S000002771	ORF	Verified	YDR363W	ESC2	4	1199173	1200543	W	Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins
11498	S000006616	tRNA	n.a.	tK(CUU)D1	n.a.	4	1201740	1201812	W	tRNA-Lys
11500	S000007235	ORF	Verified	YDR363W-A	SEM1	4	1202118	1202387	W	Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; ortholog of human DSS1
11502	S000002772	ORF	Verified	YDR364C	CDC40	4	1204200	1202833	C	Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats
11504	S000002773	ORF	Verified	YDR365C	ESF1	4	1206373	1204487	C	Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels
11515	S000002774	ORF	Uncharacterized	YDR366C	n.a.	4	1212826	1212428	C	Hypothetical protein
11517	S000002775	ORF	Uncharacterized	YDR367W	n.a.	4	1212838	1213604	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
11520	S000032664	intron	n.a.	n.a.	n.a.	4	1212868	1212968	W	n.a.
11521	S000002776	ORF	Verified	YDR368W	YPR1	4	1213894	1214832	W	2-methylbutyraldehyde reductase, may be involved in isoleucine catabolism
11523	S000002777	ORF	Verified	YDR369C	XRS2	4	1217570	1215006	C	Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling
11525	S000002778	ORF	Uncharacterized	YDR370C	n.a.	4	1219100	1217772	C	Hypothetical protein
11527	S000002779	ORF	Uncharacterized	YDR371W	CTS2	4	1219403	1220938	W	Sporulation-specific chitinase
11529	S000028822	ORF	Dubious	YDR371C-A	n.a.	4	1219603	1219499	C	Identified by expression profiling and mass spectrometry
11531	S000002780	ORF	Verified	YDR372C	VPS74	4	1222139	1221102	C	Non-essential protein of unknown function involved in vacuolar protein sorting; belongs to a family of cytosolic Golgi-associated proteins suggesting that it may play a role in secretion; also detected in the nucleus
11533	S000002781	ORF	Verified	YDR373W	FRQ1	4	1222749	1223321	W	N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily
11535	S000002782	ORF	Uncharacterized	YDR374C	n.a.	4	1224384	1223464	C	Hypothetical protein
11537	S000002783	ORF	Verified	YDR375C	BCS1	4	1226526	1225156	C	Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required for the assembly of the cytochrome bc(1) complex from the Rip1p and Qcr10p proteins; member of the CDC48/PAS1/SEC18 ATPase family
11539	S000002784	ORF	Verified	YDR376W	ARH1	4	1226812	1228293	W	Oxidoreductase of the mitochondrial inner membrane, involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability
11541	S000002785	ORF	Verified	YDR377W	ATP17	4	1228601	1228906	W	Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis
11543	S000002786	ORF	Verified	YDR378C	LSM6	4	1229710	1229339	C	Component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
11545	S000002787	ORF	Verified	YDR379W	RGA2	4	1230157	1233186	W	GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth
11547	S000007605	ORF	Uncharacterized	YDR379C-A	n.a.	4	1233507	1233268	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
11549	S000002788	ORF	Verified	YDR380W	ARO10	4	1234208	1236115	W	Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway
11551	S000002789	ORF	Verified	YDR381W	YRA1	4	1236548	1237994	W	Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function
11554	S000037617	intron	n.a.	n.a.	n.a.	4	1236833	1237598	W	n.a.
11555	S000007650	ORF	Uncharacterized	YDR381C-A	n.a.	4	1238840	1238302	C	Hypothetical protein identified by homology. See FEBS Letters [2000]487:31-36.
11558	S000037339	intron	n.a.	n.a.	n.a.	4	1238814	1238621	C	n.a.
11559	S000002790	ORF	Verified	YDR382W	RPP2B	4	1239482	1239814	W	Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm
11561	S000002791	ORF	Verified	YDR383C	NKP1	4	1240666	1239950	C	Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)
11563	S000002792	ORF	Verified	YDR384C	ATO3	4	1242021	1241194	C	Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; member of the TC 9.B.33 YaaH family of putative transporters
11565	S000002793	ORF	Verified	YDR385W	EFT2	4	1243220	1245748	W	Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin
11567	S000002794	ORF	Verified	YDR386W	MUS81	4	1246074	1247972	W	Helix-hairpin-helix protein, involved in DNA repair and replication fork stability; functions as an endonuclease in complex with Mms4p; interacts with Rad54p
11569	S000002795	ORF	Uncharacterized	YDR387C	n.a.	4	1249811	1248144	C	Hypothetical protein
11571	S000002796	ORF	Verified	YDR388W	RVS167	4	1250176	1251624	W	Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in regulation of actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin
11573	S000002797	ORF	Verified	YDR389W	SAC7	4	1252527	1254491	W	GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate
11575	S000002798	ORF	Verified	YDR390C	UBA2	4	1256837	1254927	C	Nuclear protein that acts as a heterodimer with Aos1p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability
11577	S000006572	tRNA	n.a.	tG(CCC)D	SUF3	4	1257069	1256998	C	tRNA-Gly
11579	S000002799	ORF	Uncharacterized	YDR391C	n.a.	4	1258046	1257348	C	Hypothetical protein
11581	S000002800	ORF	Verified	YDR392W	SPT3	4	1258686	1259699	W	Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters
11583	S000002801	ORF	Verified	YDR393W	SHE9	4	1259891	1261261	W	Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex
11585	S000002802	ORF	Verified	YDR394W	RPT3	4	1261671	1262957	W	One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B
11587	S000002803	ORF	Verified	YDR395W	SXM1	4	1263314	1266148	W	Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1
11589	S000002804	ORF	Dubious	YDR396W	n.a.	4	1266285	1266785	W	Protein required for cell viability
11591	S000002805	ORF	Verified	YDR397C	NCB2	4	1266888	1266356	C	Beta subunit of the NC2 dimeric histone-fold complex; represses RNA polymerase II transcription through binding to TBP and inhibition of TFIIA and TFIIB; homologous to the Dr1 subunit of the mammalian NC2 (negative cofactor2)
11594	S000034924	intron	n.a.	n.a.	n.a.	4	1266851	1266760	C	n.a.
11595	S000002806	ORF	Verified	YDR398W	UTP5	4	1267461	1269392	W	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
11597	S000002807	ORF	Verified	YDR399W	HPT1	4	1270058	1270723	W	Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
11599	S000002808	ORF	Verified	YDR400W	URH1	4	1271053	1272075	W	Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in recycling pyrimidine deoxy- and ribonucleosides via the pyrimidine salvage pathway
11601	S000002809	ORF	Dubious	YDR401W	n.a.	4	1272213	1272776	W	Hypothetical protein
11603	S000002810	ORF	Verified	YDR402C	DIT2	4	1273693	1272224	C	N-formyltyrosine oxidase, sporulation-specific microsomal enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall, homologous to cytochrome P-450s
11605	S000002811	ORF	Verified	YDR403W	DIT1	4	1274592	1276202	W	Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure
11607	S000002812	ORF	Verified	YDR404C	RPB7	4	1277159	1276644	C	RNA polymerase II subunit B16; forms two subunit dissociable complex with Rpb4p
11609	S000002813	ORF	Verified	YDR405W	MRP20	4	1277636	1278427	W	Mitochondrial ribosomal protein of the large subunit
11611	S000002814	ORF	Verified	YDR406W	PDR15	4	1279200	1283789	W	ATP binding cassette (ABC) transporter of the plasma membrane; general stress response factor implicated in cellular detoxification; target of Pdr1p, Pdr3p and Pdr8p transcription regulators; promoter contains a PDR responsive element
11613	S000028543	ORF	Dubious	YDR406W-A	n.a.	4	1283789	1284034	W	Identified by fungal homology and RT-PCR
11615	S000002815	ORF	Verified	YDR407C	TRS120	4	1287928	1284059	C	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic
11617	S000002816	ORF	Verified	YDR408C	ADE8	4	1288849	1288205	C	Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway
11619	S000002817	ORF	Verified	YDR409W	SIZ1	4	1289396	1292110	W	SUMO ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring
11621	S000002818	ORF	Verified	YDR410C	STE14	4	1293081	1292362	C	Farnesyl cysteine-carboxyl methyltransferase, mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane
11623	S000002819	ORF	Uncharacterized	YDR411C	DFM1	4	1294384	1293359	C	Protein of unknown function, localizes to the ER, contains four transmembrane domains; member of the Der1p-like family
11625	S000002820	ORF	Uncharacterized	YDR412W	n.a.	4	1294683	1295390	W	Protein required for cell viability
11627	S000002821	ORF	Dubious	YDR413C	n.a.	4	1295401	1294826	C	Protein required for cell viability
11629	S000002822	ORF	Verified	YDR414C	ERD1	4	1296676	1295588	C	Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)
11631	S000002823	ORF	Uncharacterized	YDR415C	n.a.	4	1298151	1297027	C	Hypothetical protein
11633	S000002824	ORF	Verified	YDR416W	SYF1	4	1298422	1301001	W	Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression; similar to Drosophila crooked neck protein
11635	S000002826	ORF	Verified	YDR418W	RPL12B	4	1301606	1302103	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
11637	S000002825	ORF	Dubious	YDR417C	n.a.	4	1301916	1301545	C	Hypothetical protein
11639	S000002827	ORF	Verified	YDR419W	RAD30	4	1303164	1305062	W	DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins
11641	S000006723	tRNA	n.a.	tS(AGA)D3	n.a.	4	1305620	1305702	W	tRNA-Ser
11643	S000002828	ORF	Verified	YDR420W	HKR1	4	1306257	1311665	W	Serine/threonine rich cell surface protein that contains an EF hand motif; involved in the regulation of cell wall beta-1,3 glucan synthesis and bud site selection; overexpression confers resistance to Hansenula mrakii killer toxin, HM-1
11645	S000002829	ORF	Verified	YDR421W	ARO80	4	1312030	1314882	W	Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids
11647	S000002830	ORF	Verified	YDR422C	SIP1	4	1317907	1315316	C	Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions
11649	S000002831	ORF	Verified	YDR423C	CAD1	4	1319265	1318036	C	AP-1-like bZIP transcriptional activator involved in multiple stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins, binds consensus sequence TTACTAA; 5' UTR contains uORFs
11651	S000002832	ORF	Verified	YDR424C	DYN2	4	1319831	1319377	C	Cytoplasmic light chain dynein, microtubule motor protein
11655	S000033952	intron	n.a.	n.a.	n.a.	4	1319687	1319608	C	n.a.
11656	S000033951	intron	n.a.	n.a.	n.a.	4	1319806	1319711	C	n.a.
11657	S000002833	ORF	Verified	YDR425W	SNX41	4	1320054	1321931	W	Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; forms a complex with Snx4p and Atg20p
11659	S000002834	ORF	Dubious	YDR426C	n.a.	4	1321996	1321619	C	Hypothetical protein
11661	S000002835	ORF	Verified	YDR427W	RPN9	4	1322195	1323376	W	Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects
11663	S000002836	ORF	Uncharacterized	YDR428C	n.a.	4	1324229	1323444	C	Hypothetical protein
11665	S000002837	ORF	Verified	YDR429C	TIF35	4	1325291	1324467	C	Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation
11667	S000002839	ORF	Dubious	YDR431W	n.a.	4	1328380	1328691	W	Hypothetical protein
11669	S000002838	ORF	Verified	YDR430C	CYM1	4	1328460	1325491	C	Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology
11671	S000002840	ORF	Verified	YDR432W	NPL3	4	1328773	1330017	W	RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; phosphorylation by Sky1p in the cytoplasm may promote release of mRNAs
11673	S000002841	ORF	Dubious	YDR433W	n.a.	4	1329590	1330030	W	Hypothetical protein
11675	S000002842	ORF	Verified	YDR434W	GPI17	4	1331227	1332831	W	Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Sp homolog
11677	S000002843	ORF	Verified	YDR435C	PPM1	4	1333959	1332973	C	Carboxyl methyl transferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits
11679	S000002844	ORF	Verified	YDR436W	PPZ2	4	1334811	1336943	W	Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance
11681	S000002845	ORF	Verified	YDR437W	n.a.	4	1337342	1337764	W	Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P
11683	S000002846	ORF	Uncharacterized	YDR438W	n.a.	4	1338264	1339376	W	Hypothetical protein
11685	S000002847	ORF	Verified	YDR439W	LRS4	4	1339666	1340709	W	Protein involved in rDNA silencing; positively charged coiled-coil protein with limited similarity to myosin
11687	S000002848	ORF	Verified	YDR440W	DOT1	4	1342483	1344231	W	Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes, functions in gene silencing at telomeres, most likely by directly modulating chromatin structure and Sir protein localization
11689	S000002849	ORF	Verified	YDR441C	APT2	4	1345052	1344507	C	Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity
11691	S000002850	ORF	Dubious	YDR442W	n.a.	4	1345637	1346029	W	Hypothetical protein
11693	S000002851	ORF	Verified	YDR443C	SSN2	4	1349928	1345666	C	Required for stable association of Srb10p-Srb11p kinase with RNA polymerase holoenzyme; regulates YGP1 epxression; component of RNA polymerase II holoenzyme and Kornberg's mediator (SRB) subcomplex; transcription factor
11695	S000002852	ORF	Uncharacterized	YDR444W	n.a.	4	1350280	1352343	W	Hypothetical protein
11697	S000006617	tRNA	n.a.	tK(CUU)D2	n.a.	4	1352528	1352456	C	tRNA-Lys
11699	S000002853	ORF	Dubious	YDR445C	n.a.	4	1352579	1352172	C	Hypothetical protein
11703	S000002854	ORF	Verified	YDR446W	ECM11	4	1353715	1354623	W	Non-essential protein of unknown function, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure
11705	S000002855	ORF	Verified	YDR447C	RPS17B	4	1355543	1354819	C	Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similarity to rat S17 ribosomal protein
11708	S000035612	intron	n.a.	n.a.	n.a.	4	1355540	1355227	C	n.a.
11709	S000002856	ORF	Verified	YDR448W	ADA2	4	1356055	1357359	W	Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes
11711	S000002857	ORF	Verified	YDR449C	UTP6	4	1358892	1357570	C	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
11713	S000002858	ORF	Verified	YDR450W	RPS18A	4	1359913	1360788	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins
11716	S000036545	intron	n.a.	n.a.	n.a.	4	1359960	1360394	W	n.a.
11717	S000002859	ORF	Verified	YDR451C	YHP1	4	1362171	1361110	C	One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval
11719	S000002860	ORF	Verified	YDR452W	PPN1	4	1362868	1364892	W	Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer
11721	S000002861	ORF	Verified	YDR453C	TSA2	4	1365652	1365062	C	Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants
11723	S000002862	ORF	Verified	YDR454C	GUK1	4	1366817	1366254	C	Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins
11725	S000002864	ORF	Verified	YDR456W	NHX1	4	1367475	1369376	W	Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; required for osmotolerance to acute hypertonic shock
11727	S000002863	ORF	Dubious	YDR455C	n.a.	4	1367671	1367363	C	Hypothetical protein
11729	S000002865	ORF	Verified	YDR457W	TOM1	4	1369780	1379586	W	Temperature dependent Organization in Mitotic nucleus; hect-domain-containing protein, containing kinase motifs; similar to Rsp5
11731	S000002866	ORF	Uncharacterized	YDR458C	n.a.	4	1382036	1380045	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
11733	S000002867	ORF	Uncharacterized	YDR459C	n.a.	4	1383433	1382309	C	likely functions in pathway(s) outside Ras
11735	S000002868	ORF	Verified	YDR460W	TFB3	4	1383801	1384766	W	Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit
11737	S000002869	ORF	Verified	YDR461W	MFA1	4	1385166	1385276	W	Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2
11739	S000002870	ORF	Verified	YDR462W	MRPL28	4	1386063	1386506	W	Mitochondrial ribosomal protein of the large subunit
11741	S000002871	ORF	Verified	YDR463W	STP1	4	1386806	1388365	W	Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing
11743	S000002872	ORF	Verified	YDR464W	SPP41	4	1388862	1393169	W	appears to control expression of spliceosome components PRP4 and PRP3; negative regulator of prp genes
11745	S000028614	ORF	Dubious	YDR464C-A	n.a.	4	1392670	1392482	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11747	S000002873	ORF	Verified	YDR465C	RMT2	4	1394564	1393326	C	Arginine methyltransferase; ribosomal protein L12 is a substrate
11749	S000002874	ORF	Verified	YDR466W	PKH3	4	1395111	1397807	W	Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant
11751	S000002875	ORF	Dubious	YDR467C	n.a.	4	1397899	1397573	C	Hypothetical protein
11753	S000002876	ORF	Verified	YDR468C	TLG1	4	1398690	1398016	C	Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p
11755	S000002877	ORF	Verified	YDR469W	SDC1	4	1399005	1399532	W	Subunit of the COMPASS (Set1C) complex, which methylates Rad6p ubiquitinated histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30
11757	S000002878	ORF	Verified	YDR470C	UGO1	4	1401204	1399696	C	Protein of unknown function; outer membrane component of the mitochondrial fusion machinery; Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion
11759	S000002879	ORF	Verified	YDR471W	RPL27B	4	1401760	1402554	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein
11762	S000036789	intron	n.a.	n.a.	n.a.	4	1401791	1402174	W	n.a.
11763	S000006498	snoRNA	n.a.	snR13	SNR13	4	1402909	1403032	W	small nucleolar RNA
11765	S000002880	ORF	Verified	YDR472W	TRS31	4	1403312	1404163	W	One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic
11767	S000002881	ORF	Verified	YDR473C	PRP3	4	1405844	1404435	C	Splicing factor, component of the U4/U6-U5 snRNP complex
11769	S000002883	ORF	Uncharacterized	YDR475C	n.a.	4	1410084	1407454	C	Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence
11771	S000002884	ORF	Uncharacterized	YDR476C	n.a.	4	1411117	1410443	C	Hypothetical protein
11773	S000002885	ORF	Verified	YDR477W	SNF1	4	1412363	1414264	W	AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis
11775	S000002886	ORF	Verified	YDR478W	SNM1	4	1414565	1415161	W	Subunit of RNase MRP, which cleaves pre-rRNA; not shared between Rnase MRP and nuclear Rnase P, in contrast to all other Rnase MRP protein subunits; binds to the NME1 RNA subunit of Rnase MRP
11777	S000002887	ORF	Verified	YDR479C	PEX29	4	1416864	1415200	C	Peroxisomal integral membrane protein, involved in regulation of peroxisome size and number; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p
11779	S000002888	ORF	Verified	YDR480W	DIG2	4	1417389	1418360	W	Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription
11781	S000002889	ORF	Verified	YDR481C	PHO8	4	1420240	1418540	C	Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides
11783	S000002890	ORF	Verified	YDR482C	CWC21	4	1420828	1420421	C	Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; may bind RNA; has similarity to S. pombe Cwf21p
11785	S000002891	ORF	Verified	YDR483W	KRE2	4	1421147	1422475	W	Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation
11787	S000002892	ORF	Verified	YDR484W	VPS52	4	1422753	1424678	W	Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; involved in localization of actin and chitin
11789	S000002893	ORF	Verified	YDR485C	VPS72	4	1427197	1424810	C	Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; required for vacuolar protein sorting
11791	S000002894	ORF	Verified	YDR486C	VPS60	4	1428110	1427421	C	Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport; required for normal filament maturation during pseudohyphal growth; may function in targeting specific cargo proteins for degradation
11793	S000002895	ORF	Verified	YDR487C	RIB3	4	1428970	1428344	C	3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase), required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration
11795	S000002896	ORF	Verified	YDR488C	PAC11	4	1430779	1429178	C	Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8
11797	S000002897	ORF	Verified	YDR489W	SLD5	4	1431002	1431886	W	Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which binds to DNA replication origins and facilitates assembly of the DNA replication machinery
11799	S000002898	ORF	Verified	YDR490C	PKH1	4	1434258	1431958	C	Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p
11801	S000002900	ORF	Verified	YDR492W	IZH1	4	1434914	1435864	W	Membrane protein involved in zinc metabolism, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc
11803	S000002899	ORF	Dubious	YDR491C	n.a.	4	1434981	1434490	C	Hypothetical protein
11805	S000002901	ORF	Uncharacterized	YDR493W	n.a.	4	1436207	1436578	W	The authentic, non-tagged protein was localized to the mitochondria
11807	S000002902	ORF	Verified	YDR494W	RSM28	4	1436920	1438005	W	Mitochondrial ribosomal protein of the small subunit; genetic interactions suggest a possible role in promoting translation initiation
11809	S000002903	ORF	Verified	YDR495C	VPS3	4	1441140	1438105	C	Cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase
11811	S000002904	ORF	Verified	YDR496C	PUF6	4	1443393	1441423	C	Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences in the 3' UTR and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA
11813	S000002905	ORF	Verified	YDR497C	ITR1	4	1445457	1443703	C	Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p
11815	S000002906	ORF	Verified	YDR498C	SEC20	4	1446984	1445833	C	Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; forms a complex with the cytosolic Tip20p
11817	S000002907	ORF	Verified	YDR499W	LCD1	4	1447820	1450063	W	Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1p; putative homolog of S. pombe Rad26 and human ATRIP
11819	S000002908	ORF	Verified	YDR500C	RPL37B	4	1450843	1450188	C	Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein
11822	S000036332	intron	n.a.	n.a.	n.a.	4	1450836	1450448	C	n.a.
11823	S000002909	ORF	Verified	YDR501W	PLM2	4	1451343	1452908	W	Protein required for partitioning of the 2-micron plasmid
11825	S000002910	ORF	Verified	YDR502C	SAM2	4	1454454	1453300	C	S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)
11827	S000002911	ORF	Verified	YDR503C	LPP1	4	1455856	1455032	C	Lipid phosphate phosphatase, catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA
11829	S000002912	ORF	Verified	YDR504C	SPG3	4	1456684	1456301	C	Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
11831	S000002913	ORF	Verified	YDR505C	PSP1	4	1459210	1456685	C	Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition
11833	S000002914	ORF	Uncharacterized	YDR506C	n.a.	4	1461544	1459718	C	Hypothetical protein
11835	S000006638	tRNA	n.a.	tL(CAA)D	n.a.	4	1461819	1461705	C	tRNA-Leu
11836	S000033776	intron	n.a.	n.a.	n.a.	4	1461781	1461749	C	n.a.
11839	S000002915	ORF	Verified	YDR507C	GIN4	4	1465776	1462348	C	Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p
11841	S000002917	ORF	Dubious	YDR509W	n.a.	4	1468216	1468563	W	Hypothetical protein
11843	S000002916	ORF	Verified	YDR508C	GNP1	4	1468434	1466443	C	High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids
11845	S000002918	ORF	Verified	YDR510W	SMT3	4	1469390	1469695	W	Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics
11847	S000028615	ORF	Dubious	YDR510C-A	n.a.	4	1469801	1469685	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11849	S000002919	ORF	Verified	YDR511W	ACN9	4	1470007	1470408	W	Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes
11851	S000002921	ORF	Verified	YDR513W	TTR1	4	1471007	1471438	W	Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress
11853	S000002920	ORF	Verified	YDR512C	EMI1	4	1471053	1470490	C	Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation
11855	S000002922	ORF	Uncharacterized	YDR514C	n.a.	4	1472989	1471538	C	Hypothetical protein
11857	S000002923	ORF	Verified	YDR515W	SLF1	4	1473419	1474762	W	RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA translation; involved in the copper-dependent mineralization of copper sulfide complexes on cell surface in cells cultured in copper salts
11859	S000002924	ORF	Verified	YDR516C	EMI2	4	1476466	1474964	C	Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation
11861	S000002925	ORF	Uncharacterized	YDR517W	GRH1	4	1477229	1478347	W	Golgi localized protein component of the spindle assembly checkpoint; homolog of human GRASP65, which functions in postmitotic reassembly of Golgi stacks
11863	S000002926	ORF	Verified	YDR518W	EUG1	4	1478598	1480151	W	Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER
11865	S000002927	ORF	Verified	YDR519W	FPR2	4	1480415	1480822	W	Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking
11867	S000002929	ORF	Dubious	YDR521W	n.a.	4	1483131	1483466	W	Hypothetical protein
11869	S000002928	ORF	Uncharacterized	YDR520C	n.a.	4	1483393	1481075	C	Hypothetical protein
11871	S000002930	ORF	Verified	YDR522C	SPS2	4	1485293	1483785	C	Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan layer of the spore wall; S. pombe ortholog is a spore wall component
11873	S000002931	ORF	Verified	YDR523C	SPS1	4	1487028	1485556	C	Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis
11875	S000002932	ORF	Verified	YDR524C	AGE1	4	1488980	1487532	C	ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif
11877	S000028740	ORF	Uncharacterized	YDR524W-C	n.a.	4	1489393	1489482	W	Identified by SAGE
11879	S000028739	ORF	Uncharacterized	YDR524C-B	n.a.	4	1489788	1489588	C	ORF, Uncharacterized
11881	S000002933	ORF	Dubious	YDR525W	API2	4	1489895	1490224	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 26% of ORF overlaps the dubious ORF YDR524C-A; insertion mutation in a cdc34-2 mutant background causes altered bud morphology
11883	S000028616	ORF	Dubious	YDR524C-A	n.a.	4	1489980	1489861	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11885	S000007236	ORF	Verified	YDR525W-A	SNA2	4	1490586	1490825	W	Protein of unknown function, has similarity to Pmp3p, which is involved in cation transport; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
11887	S000002935	ORF	Verified	YDR527W	RBA50	4	1491084	1492403	W	Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1
11889	S000002934	ORF	Dubious	YDR526C	n.a.	4	1491535	1491065	C	Hypothetical protein
11891	S000028466	snoRNA	n.a.	snR84	SNR84	4	1493016	1492467	C	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2265
11893	S000002936	ORF	Verified	YDR528W	HLR1	4	1494576	1495847	W	Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A
11895	S000002937	ORF	Verified	YDR529C	QCR7	4	1496538	1496155	C	Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly
11897	S000002938	ORF	Verified	YDR530C	APA2	4	1497758	1496781	C	Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p
11899	S000002939	ORF	Uncharacterized	YDR531W	n.a.	4	1498222	1499325	W	Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase, EC 2.7.1.33) catalyzes the first committed step in the universal biosynthetic pathway leading to CoA.
11901	S000002940	ORF	Uncharacterized	YDR532C	n.a.	4	1500543	1499386	C	Protein of unknown function that localizes to the nuclear side of the spindle pole body and along short spindles; forms a complex with Spc105p
11903	S000002941	ORF	Verified	YDR533C	HSP31	4	1502150	1501437	C	Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp32p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer
11905	S000002942	ORF	Verified	YDR534C	FIT1	4	1504889	1503303	C	Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall
11907	S000002943	ORF	Dubious	YDR535C	n.a.	4	1507351	1506595	C	Hypothetical protein
11910	S000032614	intron	n.a.	n.a.	n.a.	4	1507303	1507048	C	n.a.
11911	S000002944	ORF	Verified	YDR536W	STL1	4	1507994	1509703	W	Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock
11913	S000002946	ORF	Verified	YDR538W	PAD1	4	1510890	1511618	W	Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives
11915	S000002945	ORF	Dubious	YDR537C	n.a.	4	1511449	1510844	C	Hypothetical protein
11917	S000002947	ORF	Uncharacterized	YDR539W	n.a.	4	1512082	1513593	W	Hypothetical protein
11919	S000002948	ORF	Uncharacterized	YDR540C	n.a.	4	1517657	1517118	C	Hypothetical protein
11922	S000002949	ORF	Uncharacterized	YDR541C	n.a.	4	1520680	1519646	C	Hypothetical protein
11924	S000002950	ORF	Uncharacterized	YDR542W	n.a.	4	1523232	1523594	W	Hypothetical protein
11930	S000002951	ORF	Dubious	YDR543C	n.a.	4	1524916	1524617	C	Hypothetical protein
11937	S000002952	ORF	Dubious	YDR544C	n.a.	4	1525506	1525078	C	Hypothetical protein
11939	S000002953	ORF	Verified	YDR545W	YRF1-1	4	1526304	1531694	W	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
11941	S000028617	ORF	Dubious	YDR545C-A	n.a.	4	1531325	1530846	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11944	S000028621	ORF	Dubious	YEL077W-A	n.a.	5	630	1112	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
11946	S000006409	ORF	Uncharacterized	YEL077C	n.a.	5	4097	264	C	Hypothetical protein
11949	S000002956	ORF	Dubious	YEL075W-A	n.a.	5	4870	5481	W	Hypothetical protein
11951	S000000802	ORF	Uncharacterized	YEL076C	n.a.	5	5114	4464	C	Hypothetical protein
11953	S000002955	ORF	Uncharacterized	YEL076C-A	n.a.	5	5114	4185	C	Hypothetical protein
11956	S000036123	intron	n.a.	n.a.	n.a.	5	4601	4323	C	n.a.
11957	S000000801	ORF	Uncharacterized	YEL075C	n.a.	5	5713	5345	C	Hypothetical protein
11959	S000000800	ORF	Dubious	YEL074W	n.a.	5	6126	6464	W	Hypothetical protein
11967	S000000799	ORF	Uncharacterized	YEL073C	n.a.	5	7553	7230	C	Hypothetical protein
11970	S000000798	ORF	Verified	YEL072W	RMD6	5	13720	14415	W	Protein required for sporulation
11972	S000000797	ORF	Verified	YEL071W	DLD3	5	16355	17845	W	D-lactate dehydrogenase, part of the retrograde regulon which consists of genes whose expression is stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source, located in the cytoplasm
11974	S000000796	ORF	Uncharacterized	YEL070W	n.a.	5	19589	21097	W	ORF, Uncharacterized
11976	S000000795	ORF	Verified	YEL069C	HXT13	5	23231	21537	C	Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose
11978	S000000794	ORF	Dubious	YEL068C	n.a.	5	25978	25646	C	Hypothetical protein
11980	S000000792	ORF	Verified	YEL066W	HPA3	5	26667	27206	W	D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro
11982	S000000793	ORF	Dubious	YEL067C	n.a.	5	26776	26189	C	Hypothetical protein
11984	S000000791	ORF	Verified	YEL065W	SIT1	5	27657	29543	W	Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p
11986	S000000790	ORF	Verified	YEL064C	AVT2	5	31239	29797	C	Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
11988	S000000789	ORF	Verified	YEL063C	CAN1	5	33466	31694	C	Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance
11990	S000000788	ORF	Verified	YEL062W	NPR2	5	34407	36254	W	Regulator of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences
11992	S000000787	ORF	Verified	YEL061C	CIN8	5	39537	36535	C	Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation
11994	S000000786	ORF	Verified	YEL060C	PRB1	5	41953	40046	C	Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation
11996	S000002954	ORF	Verified	YEL059C-A	SOM1	5	42624	42400	C	Protein whose overexpression suppresses the imp1 mutation, may be required for the function of the Imp1p mitochondrial inner membrane peptidase and/or the protein sorting machinery
11998	S000000785	ORF	Dubious	YEL059W	n.a.	5	42652	42960	W	Hypothetical protein
12000	S000000784	ORF	Verified	YEL058W	PCM1	5	43252	44925	W	Essential N-acetylglucosamine-phosphate mutase, a hexosephosphate mutase involved in the biosynthesis of chitin
12002	S000000783	ORF	Uncharacterized	YEL057C	n.a.	5	45721	45020	C	Hypothetical protein
12004	S000000782	ORF	Verified	YEL056W	HAT2	5	47168	48373	W	Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing
12006	S000000781	ORF	Verified	YEL055C	POL5	5	51539	48471	C	Protein with sequence similarity to the human MybBP1A and weak sequence similar to B-type DNA polymerases, not required for chromosomal DNA replication; required for the synthesis of rRNA
12008	S000028744	ORF	Dubious	YEL053W-A	n.a.	5	52908	53255	W	Hypothetical protein
12010	S000000780	ORF	Verified	YEL054C	RPL12A	5	53218	52721	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins
12012	S000000779	ORF	Verified	YEL053C	MAK10	5	56102	53901	C	Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible
12014	S000000778	ORF	Verified	YEL052W	AFG1	5	56571	58100	W	Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to mitochondria
12016	S000000777	ORF	Verified	YEL051W	VMA8	5	58378	59148	W	Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis
12019	S000028545	ORF	Dubious	YEL050W-A	n.a.	5	59549	59740	W	Identified by fungal homology and RT-PCR
12021	S000000776	ORF	Verified	YEL050C	RML2	5	60851	59670	C	Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L2 ribosomal protein; fat21 mutant allele causes inability to utilize oleate and may interfere with activity of the Adr1p transcription factor
12023	S000006458	snoRNA	n.a.	snR67	SNR67	5	61352	61433	W	guides 2'-O-methylation on large subunit rRNA at G2616 and U2721; small nucleolar RNA snR67
12025	S000006444	snoRNA	n.a.	snR53	SNR53	5	61699	61789	W	guides 2'-O-methylation on small subunit rRNA at A796; small nucleolar RNA snR53
12027	S000006578	tRNA	n.a.	tG(GCC)E	n.a.	5	61960	61890	C	tRNA-Gly
12031	S000000775	ORF	Verified	YEL049W	PAU2	5	63728	64090	W	Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
12033	S000000774	ORF	Uncharacterized	YEL048C	n.a.	5	65167	64709	C	Hypothetical protein
12035	S000000773	ORF	Uncharacterized	YEL047C	n.a.	5	66797	65385	C	Fumurate ReDuctase Soluble
12037	S000000772	ORF	Verified	YEL046C	GLY1	5	68792	67629	C	Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis
12039	S000000771	ORF	Dubious	YEL045C	n.a.	5	69265	68840	C	Hypothetical protein
12041	S000000770	ORF	Verified	YEL044W	IES6	5	69757	70257	W	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
12043	S000000769	ORF	Uncharacterized	YEL043W	n.a.	5	70478	73348	W	Hypothetical protein
12045	S000000768	ORF	Verified	YEL042W	GDA1	5	73771	75327	W	Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate
12047	S000000767	ORF	Uncharacterized	YEL041W	n.a.	5	75944	77431	W	Hypothetical protein
12049	S000000766	ORF	Verified	YEL040W	UTR2	5	78053	79456	W	Putative glycosidase, glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance
12051	S000000765	ORF	Verified	YEL039C	CYC7	5	79977	79636	C	Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration
12053	S000000764	ORF	Verified	YEL038W	UTR4	5	80420	81145	W	Protein of unknown function, found in both the cytoplasm and nucleus
12055	S000000763	ORF	Verified	YEL037C	RAD23	5	82603	81407	C	Protein with ubiquitin-like N terminus, recognizes and binds damaged DNA (with Rad4p) during nucleotide excision repair; regulates Rad4p levels, subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human HR23A and HR23B proteins
12057	S000000762	ORF	Verified	YEL036C	ANP1	5	84552	83050	C	Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol
12059	S000000761	ORF	Uncharacterized	YEL035C	UTR5	5	85545	85045	C	Protein of unknown function; transcription may be regulated by Gcr1p
12061	S000000760	ORF	Verified	YEL034W	HYP2	5	85676	86149	W	Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; undergoes an essential hypusination modification; expressed under aerobic conditions
12063	S000000759	ORF	Dubious	YEL033W	n.a.	5	86179	86598	W	Hypothetical protein
12065	S000028743	ORF	Dubious	YEL034C-A	n.a.	5	86215	85613	C	Hypothetical protein
12067	S000006724	tRNA	n.a.	tS(AGA)E	n.a.	5	86604	86685	W	tRNA-Ser
12069	S000000758	ORF	Verified	YEL032W	MCM3	5	86937	89852	W	Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
12071	S000028620	ORF	Dubious	YEL032C-A	n.a.	5	87201	87040	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12073	S000000757	ORF	Verified	YEL031W	SPF1	5	90258	93905	W	P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1
12076	S000000756	ORF	Verified	YEL030W	ECM10	5	94644	96578	W	Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations
12078	S000028619	ORF	Dubious	YEL030C-A	n.a.	5	94897	94583	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12080	S000000755	ORF	Verified	YEL029C	BUD16	5	97796	96858	C	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern; has similarity to pyridoxal kinases
12082	S000000754	ORF	Dubious	YEL028W	n.a.	5	98668	99129	W	Hypothetical protein
12085	S000006660	tRNA	n.a.	tM(CAU)E	IMT4	5	100133	100204	W	Initiator methionine tRNA, tRNA(IMet), one of four initiator methionine tRNA genes in yeast that are functional for translation
12087	S000000753	ORF	Verified	YEL027W	CUP5	5	100769	101251	W	Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis
12089	S000000752	ORF	Verified	YEL026W	SNU13	5	101943	102323	W	RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein
12091	S000000751	ORF	Uncharacterized	YEL025C	n.a.	5	106147	102581	C	SWI/SNF and RSC interacting protein 1
12093	S000000750	ORF	Verified	YEL024W	RIP1	5	107260	107907	W	Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration
12095	S000000749	ORF	Uncharacterized	YEL023C	n.a.	5	110552	108504	C	Hypothetical protein
12097	S000000748	ORF	Verified	YEL022W	GEA2	5	111421	115800	W	Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p
12099	S000000747	ORF	Verified	YEL021W	URA3	5	116167	116970	W	Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound
12101	S000007256	ORF	Verified	YEL020W-A	TIM9	5	117211	117474	W	Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins
12103	S000028544	ORF	Dubious	YEL020C-B	n.a.	5	117380	117183	C	Identified by fungal homology and RT-PCR
12105	S000006490	ncRNA	n.a.	RPR1	RPR1	5	118035	117667	C	RNA component of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; may be responsible for recognition of substrate tRNAs
12108	S000000746	ORF	Uncharacterized	YEL020C	n.a.	5	120299	118617	C	Hypothetical protein
12110	S000000745	ORF	Verified	YEL019C	MMS21	5	121301	120498	C	SUMO ligase involved in chromosomal organization and DNA repair; forms a complex with Smc5p, Rhc18p, and Nse1p; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination
12112	S000000744	ORF	Uncharacterized	YEL018W	EAF5	5	121471	122310	W	Esa1p-associated factor, subunit of the NuA4 acetyltransferase complex
12114	S000028742	ORF	Dubious	YEL018C-A	n.a.	5	121988	121455	C	Questionable ORF from MIPS
12116	S000002103	ORF	Verified	YEL017C-A	PMP2	5	122929	122798	C	May regulate plasma membrane H(+)-ATPase; nearly identical to PMP1; Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p)
12118	S000000743	ORF	Uncharacterized	YEL017W	GTT3	5	123657	124670	W	Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery
12120	S000000742	ORF	Uncharacterized	YEL016C	n.a.	5	126218	124737	C	Hypothetical protein
12122	S000000741	ORF	Verified	YEL015W	EDC3	5	126629	128284	W	Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies
12124	S000000740	ORF	Dubious	YEL014C	n.a.	5	128608	128303	C	Hypothetical protein
12126	S000000739	ORF	Verified	YEL013W	VAC8	5	128825	130561	W	Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions
12128	S000006697	tRNA	n.a.	tQ(UUG)E2	n.a.	5	131153	131082	C	tRNA-Gln
12130	S000000738	ORF	Verified	YEL012W	UBC8	5	131772	132551	W	Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro
12133	S000033014	intron	n.a.	n.a.	n.a.	5	131777	131899	W	n.a.
12134	S000000737	ORF	Verified	YEL011W	GLC3	5	133120	135234	W	Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
12136	S000006618	tRNA	n.a.	tK(CUU)E1	n.a.	5	135497	135425	C	tRNA-Lys
12139	S000000736	ORF	Dubious	YEL010W	n.a.	5	136279	136629	W	Hypothetical protein
12141	S000028741	ORF	Dubious	YEL009C-A	n.a.	5	136778	136371	C	Questionable ORF from MIPS
12145	S000006710	tRNA	n.a.	tR(UCU)E	n.a.	5	138666	138737	W	tRNA-Arg
12147	S000000735	ORF	Verified	YEL009C	GCN4	5	139763	138918	C	Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels
12149	S000000734	ORF	Dubious	YEL008W	n.a.	5	140512	140892	W	Hypothetical protein
12151	S000028618	ORF	Dubious	YEL008C-A	n.a.	5	140818	140726	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12153	S000000733	ORF	Uncharacterized	YEL007W	n.a.	5	141891	143891	W	Hypothetical protein
12155	S000000732	ORF	Uncharacterized	YEL006W	n.a.	5	144326	145333	W	Hypothetical protein
12158	S000000731	ORF	Verified	YEL005C	VAB2	5	146754	145906	C	Protein with a potential role in vacuolar function, as suggested by its ability to bind Vac8p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
12160	S000000730	ORF	Verified	YEL004W	YEA4	5	146950	147978	W	Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter required for cell wall chitin synthesis; localized to the ER
12162	S000000729	ORF	Verified	YEL003W	GIM4	5	148227	148598	W	Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it
12164	S000000728	ORF	Verified	YEL002C	WBP1	5	150013	148721	C	Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum
12166	S000000727	ORF	Uncharacterized	YEL001C	n.a.	5	150977	150300	C	Hypothetical protein
12172	S000000803	ORF	Verified	YER001W	MNN1	5	153519	155807	W	Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family
12174	S000000804	ORF	Verified	YER002W	NOP16	5	156802	157497	W	Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis
12176	S000000805	ORF	Verified	YER003C	PMI40	5	159117	157735	C	Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation
12179	S000033754	intron	n.a.	n.a.	n.a.	5	159086	158994	C	n.a.
12180	S000000806	ORF	Uncharacterized	YER004W	n.a.	5	159579	160274	W	The authentic, non-tagged protein was localized to the mitochondria
12182	S000000807	ORF	Verified	YER005W	YND1	5	160549	162441	W	Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p
12184	S000000808	ORF	Verified	YER006W	NUG1	5	162722	164284	W	GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60S ribosomal subunits from the nucleus
12186	S000000809	ORF	Verified	YER007W	PAC2	5	164526	166082	W	Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl
12188	S000028745	ORF	Dubious	YER006C-A	n.a.	5	164660	164343	C	Questionable ORF from MIPS
12190	S000002957	ORF	Uncharacterized	YER007C-A	n.a.	5	166884	166236	C	Hypothetical protein
12193	S000032951	intron	n.a.	n.a.	n.a.	5	166873	166771	C	n.a.
12194	S000006499	snRNA	n.a.	snR14	SNR14	5	167585	167426	C	U4 spliceosomal RNA; interacts with U6; snRNA U4
12196	S000000810	ORF	Verified	YER008C	SEC3	5	171817	167807	C	Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion
12198	S000000811	ORF	Verified	YER009W	NTF2	5	172114	172491	W	Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport
12200	S000000812	ORF	Uncharacterized	YER010C	n.a.	5	173337	172633	C	Hypothetical protein
12203	S000000813	ORF	Verified	YER011W	TIR1	5	175247	176011	W	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking
12206	S000006550	tRNA	n.a.	tE(UUC)E1	n.a.	5	177098	177169	W	tRNA-Glu
12208	S000000814	ORF	Verified	YER012W	PRE1	5	177834	178430	W	20S proteasome beta-type subunit; localizes to the nucleus throughout the cell cycle
12210	S000000815	ORF	Verified	YER013W	PRP22	5	178840	182277	W	DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes
12212	S000000816	ORF	Verified	YER014W	HEM14	5	182599	184218	W	Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX
12214	S000000817	ORF	Verified	YER015W	FAA2	5	184540	186774	W	Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids
12216	S000007590	ORF	Uncharacterized	YER014C-A	BUD25	5	184699	183730	C	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
12219	S000037102	intron	n.a.	n.a.	n.a.	5	184676	184169	C	n.a.
12220	S000000818	ORF	Verified	YER016W	BIM1	5	188276	189310	W	Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally
12222	S000000819	ORF	Verified	YER017C	AFG3	5	191787	189502	C	Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes
12224	S000000820	ORF	Verified	YER018C	SPC25	5	192623	191958	C	Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering
12226	S000000821	ORF	Verified	YER019W	ISC1	5	192796	194229	W	Inositol phosphosphingolipid phospholipase C, hydrolyzes inositolphosphosphingolipids, activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol, mediates Na+ and Li+ halotolerance, contains a P loop-like domain
12228	S000002127	ORF	Verified	YER019C-A	SBH2	5	194538	194272	C	Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p
12230	S000000822	ORF	Verified	YER020W	GPA2	5	195167	196516	W	Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
12232	S000000823	ORF	Verified	YER021W	RPN3	5	196947	198518	W	Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control
12234	S000000824	ORF	Verified	YER022W	SRB4	5	198811	200874	W	subunit of RNA polymerase II holoenzyme/mediator complex
12236	S000000825	ORF	Verified	YER023W	PRO3	5	201075	201935	W	Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis
12238	S000028622	ORF	Dubious	YER023C-A	n.a.	5	201733	201521	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12240	S000000826	ORF	Verified	YER024W	YAT2	5	202191	204962	W	Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane
12242	S000000827	ORF	Verified	YER025W	GCD11	5	205250	206833	W	Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met
12244	S000006593	tRNA	n.a.	tH(GUG)E1	n.a.	5	207356	207427	W	tRNA-His
12246	S000000828	ORF	Verified	YER026C	CHO1	5	208473	207643	C	phosphatidylserine synthase
12248	S000000829	ORF	Verified	YER027C	GAL83	5	210231	208978	C	One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain
12250	S000000830	ORF	Verified	YER028C	MIG3	5	211875	210691	C	Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes
12253	S000000831	ORF	Verified	YER029C	SMB1	5	213176	212586	C	associated with U1, U2, U4, and U5 snRNPs as part of the Sm-core that is common to all spliceosomal snRNPs; U1 snRNP protein
12255	S000000832	ORF	Uncharacterized	YER030W	n.a.	5	213415	213897	W	Hypothetical protein
12257	S000000833	ORF	Verified	YER031C	YPT31	5	214746	214075	C	GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi
12259	S000000834	ORF	Verified	YER032W	FIR1	5	215062	217692	W	Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate
12261	S000000835	ORF	Verified	YER033C	ZRG8	5	221286	218056	C	Cytoplasmic protein of unknown function, transcription is induced under conditions of zinc deficiency
12263	S000000836	ORF	Uncharacterized	YER034W	n.a.	5	221845	222402	W	Hypothetical protein
12265	S000000837	ORF	Verified	YER035W	EDC2	5	222638	223075	W	RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p
12267	S000000838	ORF	Uncharacterized	YER036C	n.a.	5	225198	223366	C	ATPase of the ATP-binding cassette (ABC) family involved in ribosome biogenesis, has similarity to Gcn20p
12269	S000000839	ORF	Verified	YER037W	PHM8	5	225888	226853	W	Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p
12271	S000000840	ORF	Verified	YER038C	KRE29	5	228251	226857	C	Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance
12273	S000028746	ORF	Dubious	YER038W-A	n.a.	5	228450	228830	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 99% of ORF overlaps the verified gene HVG1; protein product detected in mitochondria
12275	S000000841	ORF	Verified	YER039C	HVG1	5	229204	228455	C	Protein of unknown function, has homology to Vrg4p
12277	S000007226	ORF	Uncharacterized	YER039C-A	n.a.	5	229480	229262	C	Hypothetical protein
12279	S000000842	ORF	Verified	YER040W	GLN3	5	229794	231986	W	Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source
12281	S000000843	ORF	Verified	YER041W	YEN1	5	232460	234739	W	Protein of unknown function, has similarity to endonuclease Rth1p; potentially phosphorylated by Cdc28p
12283	S000000844	ORF	Verified	YER042W	MXR1	5	234936	235490	W	Peptide methionine sulfoxide reductase, reverses the oxidation of methionine residues; involved in oxidative damage repair, providing resistance to oxidative stress and regulation of lifespan
12285	S000000845	ORF	Verified	YER043C	SAH1	5	237118	235769	C	S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor
12287	S000000846	ORF	Verified	YER044C	ERG28	5	238015	237569	C	Endoplasmic reticulum membrane protein, may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p
12289	S000001954	ORF	Verified	YER044C-A	MEI4	5	239773	238459	C	Functions in early recombination; mRNA is meiosis-specific and has 88 bp intron at 5' end spliced independently of MER1.
12292	S000032767	intron	n.a.	n.a.	n.a.	5	239710	239623	C	n.a.
12293	S000000847	ORF	Verified	YER045C	ACA1	5	241500	240031	C	Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources
12295	S000000848	ORF	Verified	YER046W	SPO73	5	243179	243610	W	Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis
12297	S000028747	ORF	Dubious	YER046W-A	n.a.	5	243699	244028	W	Questionable ORF from MIPS
12299	S000000849	ORF	Verified	YER047C	SAP1	5	246502	243809	C	Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system
12301	S000000850	ORF	Verified	YER048C	CAJ1	5	248156	246981	C	Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly
12306	S000006696	tRNA	n.a.	tQ(UUG)E1	n.a.	5	250285	250356	W	tRNA-Gln
12308	S000007237	ORF	Uncharacterized	YER048W-A	n.a.	5	250717	251001	W	Similar to D. melanogaster protein; weaker homology to C. elegans protein with similarity to human cdk7/cyclin H assembly factor
12310	S000000851	ORF	Uncharacterized	YER049W	n.a.	5	251727	253661	W	Hypothetical protein
12312	S000000852	ORF	Verified	YER050C	RSM18	5	254578	253970	C	Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S18 ribosomal protein
12314	S000000853	ORF	Uncharacterized	YER051W	n.a.	5	254655	256133	W	Hypothetical protein
12316	S000000854	ORF	Verified	YER052C	HOM3	5	257957	256374	C	Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis
12319	S000000855	ORF	Verified	YER053C	PIC2	5	259638	258736	C	Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature
12321	S000007523	ORF	Uncharacterized	YER053C-A	n.a.	5	261045	260932	C	Hypothetical protein
12323	S000000856	ORF	Verified	YER054C	GIP2	5	263697	262051	C	Putative regulatory subunit of the protein phosphatase Glc7p, proposed to be involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p
12325	S000000857	ORF	Verified	YER055C	HIS1	5	265784	264891	C	ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
12327	S000000858	ORF	Verified	YER056C	FCY2	5	268112	266511	C	Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation
12329	S000002135	ORF	Verified	YER056C-A	RPL34A	5	270183	269421	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein
12332	S000031750	intron	n.a.	n.a.	n.a.	5	270146	269750	C	n.a.
12333	S000000859	ORF	Verified	YER057C	HMF1	5	271124	270735	C	Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro
12335	S000000860	ORF	Verified	YER058W	PET117	5	271766	272089	W	Protein required for assembly of cytochrome c oxidase
12337	S000000861	ORF	Verified	YER059W	PCL6	5	272622	273884	W	Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding
12339	S000000862	ORF	Verified	YER060W	FCY21	5	274565	276151	W	Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function
12341	S000002958	ORF	Verified	YER060W-A	FCY22	5	276570	278162	W	Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function
12343	S000000863	ORF	Verified	YER061C	CEM1	5	279624	278296	C	Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration
12345	S000000864	ORF	Verified	YER062C	HOR2	5	280680	279928	C	One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition
12347	S000000865	ORF	Verified	YER063W	THO1	5	281708	282364	W	Protein of unknown function; overproduction suppresses the transcriptional defect caused by an hpr1 mutation
12349	S000000866	ORF	Uncharacterized	YER064C	n.a.	5	284220	282703	C	Non-essential nuclear protein; null mutation has global effects on transcription
12351	S000000867	ORF	Verified	YER065C	ICL1	5	286912	285239	C	Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose
12355	S000006734	tRNA	n.a.	tS(UGA)E	SUP19	5	288522	288441	C	tRNA-Ser
12357	S000000868	ORF	Uncharacterized	YER066W	n.a.	5	290240	290797	W	Hypothetical protein
12359	S000000869	ORF	Uncharacterized	YER067W	n.a.	5	292064	292549	W	Hypothetical protein
12361	S000002959	ORF	Dubious	YER066C-A	n.a.	5	292201	291701	C	Hypothetical protein
12363	S000028748	ORF	Dubious	YER067C-A	n.a.	5	292561	292238	C	Questionable ORF from MIPS
12365	S000000870	ORF	Verified	YER068W	MOT2	5	293048	294811	W	Component of the CCR4-NOT transcription regulatory complex, which represses transcription, at least in part, by inhibiting functional TBP-DNA interactions and also aids in transcription elongation; interacts with C-terminal region of Not1p
12367	S000000871	ORF	Verified	YER069W	ARG5,6	5	295408	297999	W	Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p
12369	S000028749	ORF	Dubious	YER068C-A	n.a.	5	295730	295299	C	Questionable ORF from MIPS
12371	S000000872	ORF	Verified	YER070W	RNR1	5	298948	301614	W	Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
12373	S000000873	ORF	Uncharacterized	YER071C	n.a.	5	302325	301945	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
12375	S000000874	ORF	Verified	YER072W	VTC1	5	302804	303193	W	Protein involved in vacuolar maintenance
12377	S000000875	ORF	Verified	YER073W	ALD5	5	304027	305589	W	Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed
12379	S000000876	ORF	Verified	YER074W	RPS24A	5	306319	307192	W	Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein
12382	S000036671	intron	n.a.	n.a.	n.a.	5	306322	306787	W	n.a.
12383	S000007651	ORF	Verified	YER074W-A	YOS1	5	307649	308119	W	Integral membrane protein required for ER to Golgi transport; localized to the Golgi, the ER, and COPII vesicles; interacts with Yip1p and Yif1p
12387	S000037344	intron	n.a.	n.a.	n.a.	5	307743	307844	W	n.a.
12388	S000037345	intron	n.a.	n.a.	n.a.	5	307953	308063	W	n.a.
12389	S000000877	ORF	Verified	YER075C	PTP3	5	311195	308409	C	Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm
12391	S000006522	tRNA	n.a.	tA(UGC)E	n.a.	5	312091	312019	C	tRNA-Ala
12394	S000028750	ORF	Dubious	YER076W-A	n.a.	5	313386	313733	W	Questionable ORF from MIPS
12396	S000000878	ORF	Uncharacterized	YER076C	n.a.	5	313494	312586	C	Hypothetical protein
12398	S000000879	ORF	Uncharacterized	YER077C	n.a.	5	316596	314530	C	Hypothetical protein
12401	S000000880	ORF	Uncharacterized	YER078C	n.a.	5	318338	316803	C	Metallopeptidase, localized to the mitochondrial matrix
12403	S000028546	ORF	Uncharacterized	YER078W-A	n.a.	5	318642	318806	W	Identified by fungal homology and RT-PCR
12405	S000000881	ORF	Uncharacterized	YER079W	n.a.	5	318916	319548	W	Hypothetical protein
12407	S000000882	ORF	Uncharacterized	YER080W	n.a.	5	319959	321842	W	The authentic, non-tagged protein was localized to the mitochondria
12409	S000028751	ORF	Dubious	YER079C-A	n.a.	5	320236	319898	C	Hypothetical protein
12411	S000029010	ncRNA	n.a.	SRG1	SRG1	5	322208	322758	W	Non-protein-coding RNA that regulates the transcription of SER3; expression of SRG1 RNA represses expression of its neighboring gene SER3 via a transcription-interference mechanism
12413	S000000883	ORF	Verified	YER081W	SER3	5	322682	324091	W	3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p
12415	S000000884	ORF	Verified	YER082C	UTP7	5	325932	324268	C	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
12417	S000000885	ORF	Verified	YER083C	RMD7	5	327027	326170	C	Protein required for meiotic nuclear division; appears to function in DNA replication and damage response; may be involved in cell wall function
12419	S000000886	ORF	Dubious	YER084W	n.a.	5	327061	327447	W	Hypothetical protein
12421	S000028752	ORF	Dubious	YER084W-A	n.a.	5	327594	328106	W	Questionable ORF from MIPS
12423	S000000887	ORF	Uncharacterized	YER085C	n.a.	5	328136	327615	C	Hypothetical protein
12425	S000000888	ORF	Verified	YER086W	ILV1	5	328473	330203	W	Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation
12427	S000000889	ORF	Uncharacterized	YER087W	n.a.	5	330572	332302	W	Hypothetical protein
12429	S000028753	ORF	Dubious	YER087C-A	n.a.	5	332364	331813	C	Questionable ORF from MIPS
12431	S000002128	ORF	Verified	YER087C-B	SBH1	5	332826	332578	C	Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; homologous to Sbh2p
12433	S000000890	ORF	Verified	YER088C	DOT6	5	335184	333172	C	Protein of unknown function, involved in telomeric gene silencing and filamentation
12435	S000028623	ORF	Dubious	YER088W-B	n.a.	5	335923	336069	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12437	S000028754	ORF	Dubious	YER088C-A	n.a.	5	336015	335692	C	Questionable ORF from MIPS
12439	S000000891	ORF	Verified	YER089C	PTC2	5	337336	335942	C	Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation
12441	S000000892	ORF	Verified	YER090W	TRP2	5	337945	339468	W	Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p
12443	S000029725	ORF	Dubious	YER090C-A	n.a.	5	338407	338318	C	Hypothetical protein
12445	S000000893	ORF	Verified	YER091C	MET6	5	342163	339860	C	Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; also called N5-methyltetrahydrofolate homocysteine methyltransferase or 5-methyltetrahydropteroyltriglutamate homocysteine methyltransferase
12447	S000007238	ORF	Dubious	YER091C-A	n.a.	5	342607	342386	C	Hypothetical protein
12449	S000000894	ORF	Verified	YER092W	IES5	5	342851	343228	W	Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
12451	S000000895	ORF	Verified	YER093C	TSC11	5	347608	343316	C	Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain
12453	S000002960	ORF	Uncharacterized	YER093C-A	n.a.	5	348396	347908	C	Hypothetical protein
12456	S000030867	intron	n.a.	n.a.	n.a.	5	348272	348198	C	n.a.
12457	S000000896	ORF	Verified	YER094C	PUP3	5	349342	348725	C	Beta subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit C10
12459	S000000897	ORF	Verified	YER095W	RAD51	5	349976	351178	W	Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein
12461	S000000898	ORF	Verified	YER096W	SHC1	5	351694	353232	W	Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH
12468	S000006551	tRNA	n.a.	tE(UUC)E2	n.a.	5	354930	355001	W	tRNA-Glu
12470	S000000899	ORF	Dubious	YER097W	n.a.	5	355136	355465	W	Hypothetical protein
12472	S000000900	ORF	Verified	YER098W	UBP9	5	355462	357726	W	Ubiquitin-specific protease that cleaves ubiquitin-protein fusions
12474	S000000901	ORF	Verified	YER099C	PRS2	5	359057	358101	C	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes
12476	S000000902	ORF	Verified	YER100W	UBC6	5	359558	360310	W	Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway
12478	S000000903	ORF	Verified	YER101C	AST2	5	361790	360498	C	Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions
12480	S000000904	ORF	Verified	YER102W	RPS8B	5	363096	363698	W	Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein
12482	S000000905	ORF	Verified	YER103W	SSA4	5	364585	366513	W	Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation
12484	S000000906	ORF	Verified	YER104W	RTT105	5	366798	367424	W	Protein with a role in regulation of Ty1 transposition
12486	S000000907	ORF	Verified	YER105C	NUP157	5	372009	367834	C	Abundant subunit of the nuclear pore complex (NPC), present on both sides of the NPC, has similarity to Nup170p
12488	S000000908	ORF	Verified	YER106W	MAM1	5	372322	373230	W	Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle
12490	S000028755	ORF	Dubious	YER107W-A	n.a.	5	374390	374710	W	Questionable ORF from MIPS
12492	S000000909	ORF	Verified	YER107C	GLE2	5	374541	373444	C	Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import, homologous to S. pombe Rae1p
12494	S000000911	ORF	Verified	YER109C	FLO8	5	377610	375211	C	Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene
12496	S000000912	ORF	Verified	YER110C	KAP123	5	382099	378758	C	Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1
12498	S000000913	ORF	Verified	YER111C	SWI4	5	385872	382591	C	DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair
12500	S000000914	ORF	Verified	YER112W	LSM4	5	387228	387791	W	Component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
12502	S000000915	ORF	Uncharacterized	YER113C	n.a.	5	390048	387928	C	Hypothetical protein
12504	S000000916	ORF	Verified	YER114C	BOI2	5	393708	390586	C	Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain
12506	S000000917	ORF	Verified	YER115C	SPR6	5	394863	394288	C	Protein of unknown function, expressed during sporulation; not required for sporulation, but gene exhibits genetic interactions with other genes required for sporulation
12508	S000000918	ORF	Verified	YER116C	SLX8	5	396168	395344	C	Protein containing a RING finger domain that forms a complex with Hex3p; mutant phenotypes and genetic interactions suggest a possible role in resolving recombination intermediates during DNA replication or repair
12510	S000000919	ORF	Verified	YER117W	RPL23B	5	396765	397649	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins
12513	S000033046	intron	n.a.	n.a.	n.a.	5	396807	397277	W	n.a.
12514	S000000920	ORF	Verified	YER118C	SHO1	5	399051	397948	C	Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway
12516	S000000921	ORF	Verified	YER119C	AVT6	5	400838	399492	C	Vacuolar transporter, exports aspartate and glutamate from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
12518	S000000922	ORF	Verified	YER120W	SCS2	5	401131	401865	W	Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog
12520	S000002961	ORF	Dubious	YER119C-A	n.a.	5	401234	400863	C	Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene SCS2
12522	S000000923	ORF	Dubious	YER121W	n.a.	5	402371	402715	W	Hypothetical protein
12524	S000000924	ORF	Verified	YER122C	GLO3	5	404348	402867	C	ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p
12526	S000000925	ORF	Verified	YER123W	YCK3	5	404809	406383	W	Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p
12529	S000000926	ORF	Verified	YER124C	DSE1	5	409059	407338	C	Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall
12531	S000000927	ORF	Verified	YER125W	RSP5	5	410185	412614	W	Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; plays a role in heat shock element (HSE)-mediated gene expression and multivesicular body sorting; contains a hect (homologous to E6-AP carboxyl terminus) domain
12533	S000000928	ORF	Verified	YER126C	NSA2	5	414175	413390	C	Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis
12535	S000000929	ORF	Verified	YER127W	LCP5	5	414477	415550	W	Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus
12537	S000000930	ORF	Uncharacterized	YER128W	n.a.	5	415855	416466	W	Hypothetical protein
12539	S000000931	ORF	Verified	YER129W	n.a.	5	417277	420705	W	Upstream kinase for the SNF1 complex; partially redundant function with Elm1p and Tos3p; members of this family of kinases have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
12541	S000000932	ORF	Uncharacterized	YER130C	n.a.	5	422442	421111	C	Hypothetical protein
12543	S000000933	ORF	Verified	YER131W	RPS26B	5	423948	424307	W	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein
12545	S000006493	snoRNA	n.a.	snR4	SNR4	5	424694	424879	W	small nucleolar RNA snR4
12547	S000000934	ORF	Verified	YER132C	PMD1	5	430445	425184	C	Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions
12549	S000006443	snoRNA	n.a.	snR52	SNR52	5	431216	431125	C	Small nucleolar RNA that guides the formation of 2'-O-methylation at position A420 of the small ribosomal subunit rRNA and U2921 of the large ribosomal subunit 35S pre-rRNA
12552	S000000935	ORF	Verified	YER133W	GLC7	5	432491	433954	W	Catalytic subunit of type 1 serine/threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p
12555	S000032309	intron	n.a.	n.a.	n.a.	5	432668	433192	W	n.a.
12556	S000006594	tRNA	n.a.	tH(GUG)E2	n.a.	5	434608	434537	C	tRNA-His
12560	S000006619	tRNA	n.a.	tK(CUU)E2	n.a.	5	435820	435748	C	tRNA-Lys
12564	S000028756	ORF	Dubious	YER133W-A	n.a.	5	437187	437528	W	Questionable ORF from MIPS
12566	S000000936	ORF	Uncharacterized	YER134C	n.a.	5	437799	437263	C	Hypothetical protein
12568	S000000937	ORF	Dubious	YER135C	n.a.	5	438340	437948	C	Hypothetical protein
12570	S000006753	tRNA	n.a.	tV(AAC)E1	n.a.	5	438696	438769	W	tRNA-Val
12573	S000000938	ORF	Verified	YER136W	GDI1	5	439612	440967	W	GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins
12575	S000028757	ORF	Dubious	YER137W-A	n.a.	5	441571	441876	W	Questionable ORF from MIPS
12577	S000000939	ORF	Uncharacterized	YER137C	n.a.	5	441815	441369	C	Hypothetical protein
12579	S000006491	ncRNA	n.a.	SCR1	SCR1	5	441983	442504	W	small cytoplasmic RNA 1
12583	S000006602	tRNA	n.a.	tI(AAU)E1	n.a.	5	443271	443198	C	tRNA-Ile
12595	S000007239	ORF	Uncharacterized	YER138W-A	n.a.	5	449470	449574	W	Similar to TyB and TyA
12597	S000000941	ORF	Uncharacterized	YER139C	n.a.	5	451238	450558	C	Hypothetical protein
12599	S000000942	ORF	Uncharacterized	YER140W	n.a.	5	451560	453230	W	Hypothetical protein
12601	S000000943	ORF	Verified	YER141W	COX15	5	453454	454914	W	Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase
12603	S000000944	ORF	Verified	YER142C	MAG1	5	456031	455141	C	3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired
12605	S000000945	ORF	Verified	YER143W	DDI1	5	456314	457600	W	DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (UBA) domain, may act as a negative regulator of constitutive exocytosis, may play a role in S-phase checkpoint control
12607	S000000946	ORF	Verified	YER144C	UBP5	5	460218	457801	C	Putative ubiquitin-specific protease that does not associate with the proteasome
12609	S000000947	ORF	Verified	YER145C	FTR1	5	461735	460521	C	High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron
12611	S000000948	ORF	Verified	YER146W	LSM5	5	462580	462861	W	Component of small nuclear ribonucleoprotein complexes involved in RNA processing, splicing, and decay
12613	S000028758	ORF	Dubious	YER145C-A	n.a.	5	462818	462381	C	Questionable ORF from MIPS
12615	S000000949	ORF	Verified	YER147C	SCC4	5	464837	462963	C	Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX
12617	S000000950	ORF	Verified	YER148W	SPT15	5	465298	466020	W	TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability
12619	S000028759	ORF	Dubious	YER147C-A	n.a.	5	465608	465198	C	Hypothetical protein
12621	S000028760	ORF	Dubious	YER148W-A	n.a.	5	466180	466758	W	Questionable ORF from MIPS
12623	S000000951	ORF	Verified	YER149C	PEA2	5	467465	466203	C	Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; forms polarisome complex with Bni1p, Bud6p, and Spa2p; localizes to sites of polarized growth
12625	S000000952	ORF	Verified	YER150W	SPI1	5	468365	468811	W	GPI-anchored, serine/threonine rich cell wall protein of unknown function; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p
12627	S000006754	tRNA	n.a.	tV(AAC)E2	n.a.	5	469452	469525	W	tRNA-Val
12629	S000000953	ORF	Verified	YER151C	UBP3	5	472419	469681	C	Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin
12631	S000028761	ORF	Dubious	YER152W-A	n.a.	5	473480	474046	W	Questionable ORF from MIPS
12633	S000000954	ORF	Uncharacterized	YER152C	n.a.	5	473983	472652	C	Hypothetical protein
12635	S000000955	ORF	Verified	YER153C	PET122	5	474800	474036	C	Specific translational activator for the COX3 mRNA that acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane
12637	S000000956	ORF	Verified	YER154W	OXA1	5	475015	476223	W	Translocase of the mitochondrial inner membrane, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; null is respiratory deficient
12639	S000000957	ORF	Verified	YER155C	BEM2	5	482843	476340	C	Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence
12641	S000000958	ORF	Uncharacterized	YER156C	n.a.	5	484336	483320	C	Hypothetical protein
12643	S000000959	ORF	Verified	YER157W	COG3	5	484783	487188	W	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
12645	S000006552	tRNA	n.a.	tE(UUC)E3	n.a.	5	487397	487326	C	tRNA-Glu
12648	S000000960	ORF	Uncharacterized	YER158C	n.a.	5	490573	488852	C	Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p
12650	S000028624	ORF	Dubious	YER158W-A	n.a.	5	491482	491697	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12652	S000000961	ORF	Verified	YER159C	BUR6	5	491953	491525	C	Protein that forms a heterodimeric histone-fold NC2 general transcription regulator complex with Ydr1p that binds to TBP and represses RNA pol II transcription during assembly of the preinitiation complex, homologous to human NC2alpha
12654	S000006701	tRNA	n.a.	tR(ACG)E	n.a.	5	492419	492347	C	tRNA-Arg
12666	S000000963	ORF	Verified	YER161C	SPT2	5	500343	499342	C	Protein involved in negative regulation of transcription, exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins
12668	S000000964	ORF	Verified	YER162C	RAD4	5	502889	500625	C	Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein
12670	S000000965	ORF	Uncharacterized	YER163C	n.a.	5	503777	503079	C	Hypothetical protein
12672	S000000966	ORF	Verified	YER164W	CHD1	5	505387	509793	W	Sole S. cerevisiae member of CHD gene family containing Chromodomain, Helicase domain, and DNA-binding domain; transcriptional regulator
12674	S000000967	ORF	Verified	YER165W	PAB1	5	510368	512101	W	Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G
12676	S000000968	ORF	Verified	YER166W	DNF1	5	512739	517454	W	Non-essential P-type ATPase that is a potential aminophospholipid translocase, localizes to the plasma membrane and late exocytic or early endocytic membranes, likely involved in protein transport
12678	S000028762	ORF	Dubious	YER165C-A	n.a.	5	512978	512622	C	Questionable ORF from MIPS
12680	S000000969	ORF	Verified	YER167W	BCK2	5	518211	520766	W	Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations
12683	S000000970	ORF	Verified	YER168C	CCA1	5	522664	521024	C	tRNA nucleotidyltransferase (tRNA CCA-pyrophosphorylase)
12685	S000000971	ORF	Verified	YER169W	RPH1	5	523364	525754	W	Transcriptional repressor of PHR1, which is a photolyase induced by DNA damage; binds to AG(4) (C(4)T) sequence upstream of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway
12687	S000000972	ORF	Verified	YER170W	ADK2	5	525969	526646	W	Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background
12689	S000000973	ORF	Verified	YER171W	RAD3	5	527077	529413	W	5' to 3' DNA helicase, involved in nucleotide excision repair and transcription; subunit of RNA polymerase II transcription initiation factor TFIIH; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein
12691	S000000974	ORF	Verified	YER172C	BRR2	5	536016	529525	C	RNA-dependent ATPase RNA helicase involved in the facilitation and disruption of snRNA interactions, required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis
12693	S000000975	ORF	Verified	YER173W	RAD24	5	536295	538274	W	Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein
12695	S000028763	ORF	Dubious	YER172C-A	n.a.	5	536650	536270	C	Questionable ORF from MIPS
12697	S000000976	ORF	Verified	YER174C	GRX4	5	539163	538429	C	Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage
12699	S000000977	ORF	Verified	YER175C	TMT1	5	540358	539459	C	Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle
12701	S000028625	ORF	Uncharacterized	YER175W-A	n.a.	5	540645	540809	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12703	S000000978	ORF	Verified	YER176W	ECM32	5	541685	545050	W	DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes
12705	S000000979	ORF	Verified	YER177W	BMH1	5	545606	546409	W	14-3-3 protein, major isoform; binds proteins and DNA, involved in regulation of many processes including exocytosis and vesicle transport, Ras/MAPK signaling during pseudohyphal development, rapamycin-sensitive signaling, and others
12707	S000000980	ORF	Verified	YER178W	PDA1	5	546812	548074	W	E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA, regulated by glucose
12709	S000000981	ORF	Verified	YER179W	DMC1	5	548416	549512	W	Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein
12712	S000033130	intron	n.a.	n.a.	n.a.	5	548548	548639	W	n.a.
12714	S000000982	ORF	Verified	YER180C	ISC10	5	550522	549719	C	Protein required for sporulation, transcript is induced 7.5 hours after induction of meiosis, expected to play significant role in the formation of reproductive cells
12716	S000028437	ORF	Verified	YER180C-A	SLO1	5	551117	550860	C	SCOCO like ORF
12718	S000006603	tRNA	n.a.	tI(AAU)E2	n.a.	5	551353	551280	C	tRNA-Ile
12721	S000000983	ORF	Dubious	YER181C	n.a.	5	551791	551468	C	Hypothetical protein
12724	S000000984	ORF	Uncharacterized	YER182W	n.a.	5	552520	553254	W	The authentic, non-tagged protein was localized to the mitochondria
12726	S000000985	ORF	Verified	YER183C	FAU1	5	553964	553329	C	5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis
12728	S000000986	ORF	Uncharacterized	YER184C	n.a.	5	558675	556291	C	Hypothetical protein
12730	S000000987	ORF	Uncharacterized	YER185W	n.a.	5	559449	560360	W	Hypothetical protein
12732	S000000988	ORF	Uncharacterized	YER186C	n.a.	5	562620	561700	C	Hypothetical protein
12735	S000000989	ORF	Uncharacterized	YER187W	n.a.	5	566225	566650	W	Hypothetical protein
12737	S000000990	ORF	Dubious	YER188W	n.a.	5	568035	568754	W	Hypothetical protein
12745	S000028764	ORF	Uncharacterized	YER188C-A	n.a.	5	569902	569603	C	ORF, Uncharacterized
12751	S000000991	ORF	Uncharacterized	YER189W	n.a.	5	571150	571518	W	Hypothetical protein
12753	S000000992	ORF	Verified	YER190W	YRF1-2	5	571475	576520	W	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
12755	S000028626	ORF	Dubious	YER190C-A	n.a.	5	575374	574799	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12757	S000028627	ORF	Dubious	YER190C-B	n.a.	5	576157	575675	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12760	S000001826	ORF	Uncharacterized	YFL068W	n.a.	6	53	535	W	Hypothetical protein
12762	S000001827	ORF	Uncharacterized	YFL067W	n.a.	6	836	1363	W	Hypothetical protein
12764	S000001828	ORF	Uncharacterized	YFL066C	n.a.	6	2615	1437	C	Hypothetical protein
12766	S000001829	ORF	Uncharacterized	YFL065C	n.a.	6	3338	3030	C	Hypothetical protein
12768	S000001830	ORF	Uncharacterized	YFL064C	n.a.	6	3846	3322	C	Hypothetical protein
12773	S000001831	ORF	Dubious	YFL063W	n.a.	6	5066	5521	W	Hypothetical protein
12779	S000001832	ORF	Verified	YFL062W	COS4	6	6426	7565	W	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
12781	S000001833	ORF	Uncharacterized	YFL061W	n.a.	6	9545	10222	W	Hypothetical protein
12783	S000001834	ORF	Verified	YFL060C	SNO3	6	10969	10301	C	Protein of unknown function, nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin
12785	S000001835	ORF	Verified	YFL059W	SNZ3	6	11363	12259	W	Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3
12787	S000001836	ORF	Verified	YFL058W	THI5	6	12929	13951	W	Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13
12789	S000001837	ORF	Verified	YFL057C	AAD16	6	14763	14305	C	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role
12791	S000001838	ORF	Verified	YFL056C	AAD6	6	15431	14793	C	Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response
12793	S000001839	ORF	Uncharacterized	YFL055W	AGP3	6	17004	18680	W	Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation
12795	S000001840	ORF	Uncharacterized	YFL054C	n.a.	6	22787	20847	C	Hypothetical protein
12797	S000001841	ORF	Verified	YFL053W	DAK2	6	23423	25198	W	Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation
12799	S000001842	ORF	Uncharacterized	YFL052W	n.a.	6	28232	29629	W	Hypothetical protein
12801	S000001843	ORF	Uncharacterized	YFL051C	n.a.	6	30540	30058	C	Hypothetical protein
12805	S000001844	ORF	Verified	YFL050C	ALR2	6	35848	33272	C	Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions
12807	S000001845	ORF	Uncharacterized	YFL049W	n.a.	6	36803	38674	W	Hypothetical protein
12809	S000001846	ORF	Verified	YFL048C	EMP47	6	40180	38843	C	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport
12811	S000001847	ORF	Verified	YFL047W	RGD2	6	40421	42565	W	GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p
12813	S000001848	ORF	Uncharacterized	YFL046W	n.a.	6	42815	43438	W	The authentic, non-tagged protein was localized to the mitochondria
12815	S000001849	ORF	Verified	YFL045C	SEC53	6	44392	43628	C	Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen
12817	S000001850	ORF	Uncharacterized	YFL044C	n.a.	6	45560	44655	C	Protein of unknown function, proposed to act as a deubiquitinating (DUB) enzyme and/or transcription factor; contains a C2H2-type DNA-binding Zn finger domain; has similarity to the ovarian tumor (OTU) superfamily of cysteine proteases
12819	S000001852	ORF	Uncharacterized	YFL042C	n.a.	6	47744	45720	C	Due to a sequence change (deletion of G at 46151), YFL043C is now part of YFL042C.
12821	S000028547	ORF	Uncharacterized	YFL041W-A	n.a.	6	48734	48925	W	Identified by fungal homology and RT-PCR
12823	S000001853	ORF	Verified	YFL041W	FET5	6	49139	51007	W	Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport
12825	S000001854	ORF	Uncharacterized	YFL040W	n.a.	6	51350	52972	W	Hypothetical protein
12827	S000001855	ORF	Verified	YFL039C	ACT1	6	54695	53260	C	Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions
12830	S000034733	intron	n.a.	n.a.	n.a.	6	54685	54378	C	n.a.
12831	S000001856	ORF	Verified	YFL038C	YPT1	6	55985	55365	C	Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)
12833	S000001857	ORF	Verified	YFL037W	TUB2	6	56335	57708	W	Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules
12835	S000001858	ORF	Verified	YFL036W	RPO41	6	58781	62836	W	Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition
12837	S000001859	ORF	Verified	YFL034C-B	MOB2	6	63992	63015	C	Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein
12840	S000036509	intron	n.a.	n.a.	n.a.	6	63972	63859	C	n.a.
12841	S000006436	ORF	Verified	YFL034C-A	RPL22B	6	64931	64242	C	Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein
12844	S000036496	intron	n.a.	n.a.	n.a.	6	64919	64599	C	n.a.
12845	S000001860	ORF	Uncharacterized	YFL034W	n.a.	6	65475	68696	W	Possible integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk
12848	S000001861	ORF	Verified	YFL033C	RIM15	6	74425	69113	C	Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; originally identified as a regulator of IME2
12850	S000001862	ORF	Dubious	YFL032W	n.a.	6	74870	75190	W	Hypothetical protein
12852	S000001863	ORF	Verified	YFL031W	HAC1	6	75177	76145	W	bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway utilizing Ire1p, Trl1p and Ada5p facilitates efficient Hac1p synthesis
12855	S000031640	intron	n.a.	n.a.	n.a.	6	75838	76089	W	n.a.
12856	S000028629	ORF	Dubious	YFL031C-A	n.a.	6	76113	76012	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12858	S000001864	ORF	Verified	YFL030W	AGX1	6	76829	77986	W	Alanine : glyoxylate aminotransferase, catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine : glyoxylate aminotransferases
12860	S000001865	ORF	Verified	YFL029C	CAK1	6	79159	78053	C	Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases
12862	S000001866	ORF	Verified	YFL028C	CAF16	6	80211	79342	C	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p
12864	S000001867	ORF	Verified	YFL027C	GYP8	6	81910	80417	C	GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport
12866	S000001868	ORF	Verified	YFL026W	STE2	6	82578	83873	W	Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells
12868	S000001869	ORF	Verified	YFL025C	BST1	6	87232	84143	C	GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules
12870	S000001870	ORF	Verified	YFL024C	EPL1	6	90343	87845	C	Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex; homologous to Drosophila Enhancer of Polycomb
12872	S000001871	ORF	Verified	YFL023W	BUD27	6	90984	93374	W	Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by the TOR kinase; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
12874	S000001872	ORF	Verified	YFL022C	FRS2	6	95008	93497	C	Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar
12876	S000001873	ORF	Verified	YFL021W	GAT1	6	95964	97496	W	Transcriptional activator of genes involved in nitrogen catabolite repression, member of the GATA family of DNA binding proteins; activity and localization regulated by nitrogen limitation and Ure2p
12878	S000028766	ORF	Dubious	YFL021C-A	n.a.	6	96613	95759	C	Questionable ORF from MIPS
12880	S000001874	ORF	Verified	YFL020C	PAU5	6	99593	99225	C	Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme
12883	S000001875	ORF	Dubious	YFL019C	n.a.	6	100599	100246	C	Hypothetical protein
12885	S000006681	tRNA	n.a.	tP(UGG)F	SUF9	6	101370	101472	W	tRNA-Pro
12886	S000035980	intron	n.a.	n.a.	n.a.	6	101406	101436	W	n.a.
12889	S000001876	ORF	Verified	YFL018C	LPD1	6	103121	101622	C	Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes
12891	S000002965	ORF	Verified	YFL017W-A	SMX2	6	103693	103926	W	snRNP G protein (the homologue of the human Sm-G)
12893	S000001877	ORF	Verified	YFL017C	GNA1	6	104456	103977	C	Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA
12895	S000001878	ORF	Verified	YFL016C	MDJ1	6	106230	104695	C	Protein involved in folding of mitochondrially synthesized proteins in the mitochondrial matrix; localizes to the mitochondrial inner membrane; member of the DnaJ family of molecular chaperones
12897	S000028765	ORF	Dubious	YFL015W-A	n.a.	6	106409	106726	W	Questionable ORF from MIPS
12899	S000001879	ORF	Dubious	YFL015C	n.a.	6	106957	106463	C	Hypothetical protein
12901	S000001880	ORF	Verified	YFL014W	HSP12	6	107250	107579	W	Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways
12903	S000028628	ORF	Dubious	YFL013W-A	n.a.	6	107793	108596	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
12905	S000002964	ORF	Dubious	YFL012W-A	n.a.	6	109804	110178	W	Hypothetical protein
12907	S000001881	ORF	Verified	YFL013C	IES1	6	109924	107846	C	Subunit of the INO80 chromatin remodeling complex
12909	S000001882	ORF	Uncharacterized	YFL012W	n.a.	6	110641	111087	W	Hypothetical protein
12911	S000001883	ORF	Verified	YFL011W	HXT10	6	112339	113979	W	Putative hexose transporter, expressed at low levels and expression is repressed by glucose
12913	S000001955	ORF	Verified	YFL010W-A	AUA1	6	114984	115268	W	Protein required for the negative regulation by ammonia of Gap1p, which is a general amino acid permease
12915	S000001884	ORF	Verified	YFL010C	WWM1	6	115737	115102	C	WW domain containing protein interacting with Metacaspase (MCA1)
12917	S000001885	ORF	Verified	YFL009W	CDC4	6	116139	118478	W	F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p
12920	S000001886	ORF	Verified	YFL008W	SMC1	6	119424	123101	W	Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure
12922	S000001887	ORF	Verified	YFL007W	BLM3	6	123474	129905	W	Protein involved in assembly of proteasomal core particles in the nucleus; required for normal resistance to bleomycin, may be involved in protection against oxidative damage
12925	S000001889	ORF	Verified	YFL005W	SEC4	6	130329	130976	W	Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane
12927	S000001890	ORF	Verified	YFL004W	VTC2	6	131805	134291	W	Phosphate metabolism; transcription is regulated by PHO system; polyphosphate synthetase (putative)
12930	S000001891	ORF	Verified	YFL003C	MSH4	6	137152	134516	C	Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein
12932	S000006669	tRNA	n.a.	tN(GUU)F	n.a.	6	137554	137481	C	tRNA-Asn
12947	S000001894	ORF	Verified	YFL002C	SPB4	6	146929	145109	C	Putative ATP-dependent RNA helicase, nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients
12949	S000001895	ORF	Verified	YFL001W	DEG1	6	147126	148454	W	Non-essential tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm
12955	S000001897	ORF	Verified	YFR001W	LOC1	6	149105	149719	W	Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles
12957	S000001898	ORF	Verified	YFR002W	NIC96	6	150011	152530	W	Component of the nuclear pore complex, required for nuclear pore formation; forms a subcomplex with Nsp1p, Nup57p, and Nup49p
12959	S000001899	ORF	Verified	YFR003C	YPI1	6	153119	152652	C	Inhibitor of the type I protein phosphatase Glc7p, which is involved in regulation of a variety of metabolic processes; overproduction causes decreased cellular content of glycogen
12961	S000001900	ORF	Verified	YFR004W	RPN11	6	153388	154308	W	Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates
12963	S000001901	ORF	Verified	YFR005C	SAD1	6	155868	154522	C	Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRNA into the U4/U6 particle
12965	S000001902	ORF	Uncharacterized	YFR006W	n.a.	6	156139	157746	W	Hypothetical protein
12967	S000006564	tRNA	n.a.	tF(GAA)F	n.a.	6	158001	157910	C	tRNA-Phe
12968	S000035384	intron	n.a.	n.a.	n.a.	6	157964	157946	C	n.a.
12972	S000001903	ORF	Uncharacterized	YFR007W	n.a.	6	159293	160354	W	Hypothetical protein
12974	S000001904	ORF	Verified	YFR008W	FAR7	6	160529	161194	W	Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p
12977	S000006579	tRNA	n.a.	tG(GCC)F1	SUF20	6	162222	162292	W	tRNA-Gly
12979	S000001905	ORF	Verified	YFR009W	GCN20	6	162482	164740	W	Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA
12981	S000028823	ORF	Dubious	YFR009W-A	n.a.	6	163869	164126	W	Identified by expression profiling and mass spectrometry
12983	S000001906	ORF	Verified	YFR010W	UBP6	6	165060	166559	W	Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; deletion causes hypersensitivity to cycloheximide and other toxic compounds
12985	S000028824	ORF	Dubious	YFR010W-A	n.a.	6	166721	166909	W	Identified by expression profiling and mass spectrometry
12987	S000001907	ORF	Uncharacterized	YFR011C	n.a.	6	167251	166739	C	Hypothetical protein
12989	S000006779	tRNA	n.a.	tY(GUA)F1	SUP11	6	167430	167518	W	tRNA-Tyr
12990	S000030879	intron	n.a.	n.a.	n.a.	6	167469	167482	W	n.a.
12994	S000001908	ORF	Uncharacterized	YFR012W	n.a.	6	167881	168489	W	Hypothetical protein
12996	S000007606	ORF	Uncharacterized	YFR012W-A	n.a.	6	169216	169302	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
12998	S000001909	ORF	Verified	YFR013W	IOC3	6	169914	172277	W	Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing
13000	S000001910	ORF	Verified	YFR014C	CMK1	6	173869	172529	C	Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II
13002	S000001911	ORF	Verified	YFR015C	GSY1	6	176383	174257	C	Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase
13004	S000001912	ORF	Uncharacterized	YFR016C	n.a.	6	180735	177034	C	Hypothetical protein
13006	S000006580	tRNA	n.a.	tG(GCC)F2	n.a.	6	181036	180966	C	tRNA-Gly
13008	S000001913	ORF	Uncharacterized	YFR017C	n.a.	6	182849	182262	C	Hypothetical protein
13010	S000001914	ORF	Uncharacterized	YFR018C	n.a.	6	184210	183119	C	Hypothetical protein
13012	S000001915	ORF	Verified	YFR019W	FAB1	6	184490	191326	W	1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis
13014	S000006731	tRNA	n.a.	tS(GCU)F	n.a.	6	191601	191501	C	tRNA-Ser
13015	S000037442	intron	n.a.	n.a.	n.a.	6	191564	191546	C	n.a.
13019	S000001916	ORF	Dubious	YFR020W	n.a.	6	192726	193424	W	Hypothetical protein
13021	S000001917	ORF	Verified	YFR021W	ATG18	6	194800	196302	W	Phosphatidylinositol 3,5-bisphosphate-binding protein of the vacuolar membrane, predicted to fold as a seven-bladed beta-propeller; required for recycling of Atg9p through the pre-autophagosomal structure
13023	S000001918	ORF	Verified	YFR022W	ROG3	6	196821	199022	W	Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY motifs; has similarity to Rod1p; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant
13026	S000001919	ORF	Verified	YFR023W	PES4	6	199862	201697	W	Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p
13028	S000002968	ORF	Verified	YFR024C-A	LSB3	6	203421	201948	C	Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
13031	S000035056	intron	n.a.	n.a.	n.a.	6	203374	203257	C	n.a.
13032	S000001921	ORF	Verified	YFR025C	HIS2	6	204738	203731	C	Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control
13034	S000006511	tRNA	n.a.	tA(AGC)F	n.a.	6	204984	204912	C	tRNA-Ala
13036	S000001922	ORF	Uncharacterized	YFR026C	n.a.	6	206245	205736	C	Hypothetical protein
13039	S000001923	ORF	Verified	YFR027W	ECO1	6	207440	208285	W	Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication, but not for its maintenance during G2 and M phases; also required for postreplicative double-strand break repair; interacts with Chl1p
13041	S000001924	ORF	Verified	YFR028C	CDC14	6	210056	208401	C	Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit
13043	S000006780	tRNA	n.a.	tY(GUA)F2	SUP6	6	210695	210607	C	tRNA-Tyr
13044	S000030888	intron	n.a.	n.a.	n.a.	6	210656	210643	C	n.a.
13047	S000001925	ORF	Verified	YFR029W	PTR3	6	210925	212961	W	Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes
13049	S000001926	ORF	Verified	YFR030W	MET10	6	213300	216407	W	Subunit alpha of assimilatory sulfite reductase, which is responsible for the conversion of sulfite into sulfide
13052	S000001927	ORF	Verified	YFR031C	SMC2	6	220094	216582	C	Component of the condensin complex, essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA, possibly in the cleft formed by the coiled-coil of the folded dimer
13054	S000002104	ORF	Verified	YFR031C-A	RPL2A	6	221406	220495	C	Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins
13057	S000032330	intron	n.a.	n.a.	n.a.	6	221402	221256	C	n.a.
13058	S000001928	ORF	Uncharacterized	YFR032C	n.a.	6	222947	222078	C	Hypothetical protein
13060	S000006437	ORF	Verified	YFR032C-A	RPL29	6	223425	223246	C	Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate
13062	S000028630	ORF	Uncharacterized	YFR032C-B	n.a.	6	223961	223698	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13064	S000001929	ORF	Verified	YFR033C	QCR6	6	224757	224314	C	Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1
13066	S000001930	ORF	Verified	YFR034C	PHO4	6	225946	225008	C	Basic helix-loop-helix (bHLH) transcription factor; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability
13068	S000028631	ORF	Dubious	YFR034W-A	n.a.	6	226010	226297	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13070	S000001931	ORF	Uncharacterized	YFR035C	n.a.	6	226453	226109	C	Hypothetical protein
13072	S000006620	tRNA	n.a.	tK(CUU)F	n.a.	6	226747	226676	C	tRNA-Lys
13074	S000001932	ORF	Verified	YFR036W	CDC26	6	226950	227324	W	Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
13076	S000028767	ORF	Dubious	YFR036W-A	n.a.	6	227438	228088	W	Questionable ORF from MIPS
13078	S000001933	ORF	Verified	YFR037C	RSC8	6	229173	227500	C	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters
13080	S000001934	ORF	Uncharacterized	YFR038W	n.a.	6	229367	231928	W	Hypothetical protein
13082	S000001935	ORF	Uncharacterized	YFR039C	n.a.	6	233531	231999	C	Hypothetical protein
13084	S000001936	ORF	Verified	YFR040W	SAP155	6	234229	237237	W	Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p
13086	S000001937	ORF	Uncharacterized	YFR041C	ERJ5	6	238242	237355	C	Endoplasmic reticulum protein that may function as a cochaperone, as suggested by the presence of a DnaJ-like domain
13088	S000001938	ORF	Uncharacterized	YFR042W	n.a.	6	238445	239047	W	Protein required for cell viability
13090	S000001939	ORF	Uncharacterized	YFR043C	n.a.	6	239814	239101	C	Hypothetical protein
13092	S000001940	ORF	Uncharacterized	YFR044C	n.a.	6	241424	239979	C	Hypothetical protein
13094	S000001941	ORF	Uncharacterized	YFR045W	n.a.	6	242129	242986	W	Hypothetical protein
13096	S000001942	ORF	Verified	YFR046C	CNN1	6	244146	243061	C	Kinetochore protein of unknown function; associated with the essential kinetochore proteins Nnf11p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1.
13098	S000001943	ORF	Verified	YFR047C	BNA6	6	245153	244266	C	Quinolinate phosphoribosyl transferase, required for biosynthesis of nicotinic acid from tryptophan via kynurenine pathway
13100	S000001944	ORF	Verified	YFR048W	RMD8	6	246133	248121	W	Cytosolic protein required for sporulation
13102	S000001945	ORF	Verified	YFR049W	YMR31	6	248510	248881	W	Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36
13104	S000001946	ORF	Verified	YFR050C	PRE4	6	249853	249053	C	20S proteasome beta-type subunit
13106	S000001947	ORF	Verified	YFR051C	RET2	6	251790	250150	C	Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER
13108	S000001948	ORF	Verified	YFR052W	RPN12	6	252492	253316	W	Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p
13110	S000028768	ORF	Dubious	YFR052C-A	n.a.	6	253721	253416	C	Questionable ORF from MIPS
13112	S000001949	ORF	Verified	YFR053C	HXK1	6	255036	253579	C	Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p
13115	S000001950	ORF	Dubious	YFR054C	n.a.	6	259420	258842	C	Hypothetical protein
13117	S000001952	ORF	Uncharacterized	YFR055W	n.a.	6	264191	265213	W	Hypothetical protein
13119	S000001951	ORF	Dubious	YFR056C	n.a.	6	264312	263944	C	Hypothetical protein
13121	S000001953	ORF	Uncharacterized	YFR057W	n.a.	6	269048	269503	W	Hypothetical protein
13135	S000003232	ORF	Verified	YGL263W	COS12	7	2790	3932	W	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
13137	S000003231	ORF	Uncharacterized	YGL262W	n.a.	7	5312	5839	W	Hypothetical protein
13139	S000003230	ORF	Uncharacterized	YGL261C	n.a.	7	6652	6290	C	Hypothetical protein
13141	S000003229	ORF	Dubious	YGL260W	n.a.	7	6860	7090	W	Hypothetical protein
13143	S000003228	ORF	Uncharacterized	YGL259W	YPS5	7	8470	8967	W	Protein with similarity to GPI-anchored aspartic proteases such as Yap1p and Yap3p
13145	S000007607	ORF	Uncharacterized	YGL258W-A	n.a.	7	9162	9395	W	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
13147	S000003227	ORF	Uncharacterized	YGL258W	n.a.	7	11110	11730	W	Hypothetical protein
13149	S000003226	ORF	Verified	YGL257C	MNT2	7	14157	12481	C	Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans
13151	S000003225	ORF	Verified	YGL256W	ADH4	7	14910	16307	W	Alcohol dehydrogenase type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency; alcohol dehydrogenase isoenzyme IV
13153	S000003224	ORF	Verified	YGL255W	ZRT1	7	20978	22108	W	High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor
13155	S000003223	ORF	Verified	YGL254W	FZF1	7	22304	23203	W	Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers
13157	S000003222	ORF	Verified	YGL253W	HXK2	7	23935	25395	W	Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene
13159	S000003221	ORF	Verified	YGL252C	RTG2	7	27484	25718	C	Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p
13161	S000003220	ORF	Verified	YGL251C	HFM1	7	31636	27921	C	Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity
13164	S000035420	intron	n.a.	n.a.	n.a.	7	31578	31427	C	n.a.
13165	S000003219	ORF	Uncharacterized	YGL250W	n.a.	7	31910	32635	W	Hypothetical protein
13167	S000003218	ORF	Verified	YGL249W	ZIP2	7	33098	35212	W	Required for 'ZIPpering' up meiotic chromosomes during chromosome synapsis; involved in meiotic recombination and disjunction
13169	S000003217	ORF	Verified	YGL248W	PDE1	7	35653	36762	W	Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation
13171	S000003216	ORF	Verified	YGL247W	BRR6	7	36933	37526	W	Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores
13173	S000003215	ORF	Verified	YGL246C	RAI1	7	38780	37617	C	Nuclear protein that binds to and stabilizes the exoribonuclease Rat1p, required for pre-rRNA processing
13175	S000003214	ORF	Verified	YGL245W	GUS1	7	39023	41149	W	Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm
13177	S000003213	ORF	Verified	YGL244W	RTF1	7	41498	43174	W	Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p (TATA box-binding protein) and relative activities of different TATA elements
13179	S000003212	ORF	Verified	YGL243W	TAD1	7	43307	44509	W	tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala
13181	S000003211	ORF	Uncharacterized	YGL242C	n.a.	7	45197	44652	C	Hypothetical protein
13183	S000003210	ORF	Verified	YGL241W	KAP114	7	45445	48459	W	Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear
13185	S000003209	ORF	Verified	YGL240W	DOC1	7	48613	49365	W	Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis
13187	S000003207	ORF	Verified	YGL238W	CSE1	7	49552	52434	W	Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p), homolog of metazoan CAS protein, required for accurate chromosome segregation
13189	S000003208	ORF	Dubious	YGL239C	n.a.	7	49745	49431	C	Protein required for cell viability
13191	S000003206	ORF	Verified	YGL237C	HAP2	7	53528	52731	C	Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding
13193	S000003204	ORF	Uncharacterized	YGL235W	n.a.	7	55279	55815	W	Protein of unknown function, potential Cdc28p substrate
13195	S000003205	ORF	Verified	YGL236C	MTO1	7	55796	53787	C	Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants
13197	S000003203	ORF	Verified	YGL234W	ADE5,7	7	56482	58890	W	Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities
13199	S000003202	ORF	Verified	YGL233W	SEC15	7	59122	61854	W	Essential 113kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which mediates polarized targeting of vesicles to active sites of exocytosis; Sec15p associates with Sec4p and vesicles
13201	S000003201	ORF	Verified	YGL232W	TAN1	7	62075	63002	W	Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA
13204	S000036132	intron	n.a.	n.a.	n.a.	7	62132	62189	W	n.a.
13205	S000003200	ORF	Uncharacterized	YGL231C	n.a.	7	63620	63048	C	Hypothetical protein
13207	S000003199	ORF	Uncharacterized	YGL230C	n.a.	7	64215	63772	C	Hypothetical protein
13209	S000003198	ORF	Verified	YGL229C	SAP4	7	66959	64503	C	Protein required for function of the Sit4p protein phosphatase, member of a family of similar proteins that form complexes with Sit4p, including Sap155p, Sap185p, and Sap190p
13211	S000003197	ORF	Verified	YGL228W	SHE10	7	67598	69331	W	Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest
13213	S000003196	ORF	Verified	YGL227W	VID30	7	69671	72547	W	Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); shifts the balance of nitrogen metabolism toward the production of glutamate; localized to the nucleus and the cytoplasm
13215	S000003194	ORF	Verified	YGL226C-A	OST5	7	73157	72748	C	Zeta subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins
13218	S000037109	intron	n.a.	n.a.	n.a.	7	73136	72988	C	n.a.
13219	S000003195	ORF	Uncharacterized	YGL226W	n.a.	7	73339	73710	W	Hypothetical protein
13221	S000006757	tRNA	n.a.	tV(AAC)G3	n.a.	7	73901	73828	C	tRNA-Val
13223	S000003193	ORF	Verified	YGL225W	VRG4	7	76893	77906	W	Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi
13225	S000003192	ORF	Verified	YGL224C	SDT1	7	78856	78014	C	Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives
13227	S000003191	ORF	Verified	YGL223C	COG1	7	80364	79111	C	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
13229	S000003190	ORF	Verified	YGL222C	EDC1	7	81185	80658	C	RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p
13231	S000003189	ORF	Verified	YGL221C	NIF3	7	82291	81425	C	Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product)
13233	S000003188	ORF	Uncharacterized	YGL220W	n.a.	7	82373	82735	W	Hypothetical protein
13235	S000003186	ORF	Dubious	YGL218W	n.a.	7	83649	84299	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 93% of ORF overlaps the verified gene MDM34; deletion in cyr1 mutant results in loss of stress resistance
13237	S000003187	ORF	Verified	YGL219C	MDM34	7	84256	82877	C	Mitochondrial outer membrane protein, required for normal mitochondrial morphology and inheritance; localizes to dots on the mitochondrial surface near mtDNA nucleoids; interacts genetically with MDM31 and MDM32
13239	S000003184	ORF	Verified	YGL216W	KIP3	7	84884	87301	W	Kinesin-related motor protein involved in mitotic spindle positioning
13241	S000003185	ORF	Dubious	YGL217C	n.a.	7	85179	84838	C	Hypothetical protein
13243	S000003183	ORF	Verified	YGL215W	CLG1	7	87980	89338	W	Cyclin-like protein that interacts with Pho85p; has sequence similarity to G1 cyclins PCL1 and PCL2
13245	S000003182	ORF	Dubious	YGL214W	n.a.	7	90011	90499	W	Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation enhances replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene SKI8
13247	S000003181	ORF	Verified	YGL213C	SKI8	7	91251	90058	C	Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs as well as double-strand break formation during meiotic recombination; required for repressing propagation of dsRNA viruses
13249	S000003180	ORF	Verified	YGL212W	VAM7	7	91436	92386	W	Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-25 homolog; functions with a syntaxin homolog Vam3p in vacuolar protein trafficking
13251	S000003179	ORF	Uncharacterized	YGL211W	NCS6	7	92516	93595	W	Protein with a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
13253	S000003178	ORF	Verified	YGL210W	YPT32	7	93797	94465	W	GTPase of the Ypt/Rab family, very similar to Ypt31p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi
13255	S000003177	ORF	Verified	YGL209W	MIG2	7	95862	97010	W	Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter
13257	S000003176	ORF	Verified	YGL208W	SIP2	7	97342	98589	W	One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane
13259	S000003175	ORF	Verified	YGL207W	SPT16	7	98973	102080	W	Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure
13261	S000003174	ORF	Verified	YGL206C	CHC1	7	107508	102547	C	vesicle coat protein; presumed vesicle coat protein
13263	S000003173	ORF	Verified	YGL205W	POX1	7	108162	110408	W	Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix
13265	S000006595	tRNA	n.a.	tH(GUG)G1	n.a.	7	110700	110629	C	tRNA-His
13270	S000003172	ORF	Dubious	YGL204C	n.a.	7	112009	111704	C	Hypothetical protein
13272	S000003171	ORF	Verified	YGL203C	KEX1	7	114668	112479	C	Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins
13275	S000006630	tRNA	n.a.	tK(UUU)G1	n.a.	7	115492	115587	W	tRNA-Lys
13276	S000033672	intron	n.a.	n.a.	n.a.	7	115529	115551	W	n.a.
13279	S000003170	ORF	Verified	YGL202W	ARO8	7	116063	117565	W	Aromatic aminotransferase, expression is regulated by general control of amino acid biosynthesis
13281	S000003169	ORF	Verified	YGL201C	MCM6	7	120911	117858	C	Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex
13283	S000006621	tRNA	n.a.	tK(CUU)G1	n.a.	7	122273	122345	W	tRNA-Lys
13285	S000003168	ORF	Verified	YGL200C	EMP24	7	123310	122699	C	Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport
13287	S000003166	ORF	Verified	YGL198W	YIP4	7	123596	124303	W	Protein that interacts with Rab GTPases; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
13289	S000003167	ORF	Dubious	YGL199C	n.a.	7	124047	123577	C	Hypothetical protein
13291	S000003165	ORF	Verified	YGL197W	MDS3	7	124703	129166	W	Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions
13293	S000003164	ORF	Uncharacterized	YGL196W	n.a.	7	129888	131174	W	Hypothetical protein
13295	S000003163	ORF	Verified	YGL195W	GCN1	7	131531	139549	W	Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA
13297	S000003162	ORF	Verified	YGL194C	HOS2	7	141732	140374	C	Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity
13299	S000003161	ORF	Dubious	YGL193C	n.a.	7	142233	141922	C	Hypothetical protein
13301	S000003160	ORF	Verified	YGL192W	IME4	7	142252	144054	W	Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation; expression is induced in starved MATa/MAT alpha diploid cells
13303	S000003159	ORF	Verified	YGL191W	COX13	7	144814	145203	W	Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP
13305	S000003158	ORF	Verified	YGL190C	CDC55	7	147395	145815	C	Non-essential regulatory subunit B of protein phosphatase 2A; has multiple roles in mitosis and protein biosynthesis; found in the nucleus of most cells but also at the bud neck (large-budded cells) and at the bud tip (small-budded cells)
13307	S000003157	ORF	Verified	YGL189C	RPS26A	7	148594	148235	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein
13309	S000028635	ORF	Uncharacterized	YGL188C-A	n.a.	7	148970	148830	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13311	S000003156	ORF	Dubious	YGL188C	n.a.	7	149522	149349	C	Hypothetical protein
13313	S000003155	ORF	Verified	YGL187C	COX4	7	150177	149710	C	Subunit IV of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; N-terminal 25 residues of precursor are cleaved during mitochondrial import
13315	S000003154	ORF	Verified	YGL186C	TPN1	7	152782	151043	C	Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosine permease subfamily within the major facilitator superfamily; proton symporter with similarity to Fcy21p, Fcy2p, and Fcy22p
13317	S000003153	ORF	Uncharacterized	YGL185C	n.a.	7	154312	153173	C	Putative hydroxyacid dehydrogenase
13319	S000003152	ORF	Verified	YGL184C	STR3	7	156018	154621	C	Cystathionine beta-lyase, converts cystathionine into homocysteine
13321	S000003151	ORF	Verified	YGL183C	MND1	7	157291	156549	C	Protein required for recombination and meiotic nuclear division; forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks
13324	S000037290	intron	n.a.	n.a.	n.a.	7	157288	157206	C	n.a.
13325	S000003150	ORF	Dubious	YGL182C	n.a.	7	157602	157279	C	Hypothetical protein
13327	S000003149	ORF	Verified	YGL181W	GTS1	7	157912	159102	W	Protein containing a zinc-finger in the N-terminus and a long Gln-rich region in the C-terminus; regulates ultradian rhythm, cell size, cell cycle, lifespan, sporulation, heat tolerance, and multidrug transport
13329	S000003148	ORF	Verified	YGL180W	ATG1	7	160071	162764	W	Protein serine/threonine kinase, required for autophagy and for the cytoplasm-to-vacuole targeting (Cvt) pathway
13331	S000003147	ORF	Verified	YGL179C	TOS3	7	165097	163415	C	Protein kinase, related to and functionally redundant with Elm1p and Pak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome
13333	S000003146	ORF	Verified	YGL178W	MPT5	7	167358	170577	W	Protein that specifically binds to mRNAs encoding chromatin modifiers and spindle pole body components; has roles in longevity, in maintenance of cell wall integrity, and in sensitivity to and recovery from pheromone arrest
13336	S000034398	intron	n.a.	n.a.	n.a.	7	167361	168000	W	n.a.
13337	S000003145	ORF	Dubious	YGL177W	n.a.	7	167565	167912	W	Hypothetical protein
13339	S000003144	ORF	Uncharacterized	YGL176C	n.a.	7	173085	171421	C	Hypothetical protein
13341	S000003143	ORF	Verified	YGL175C	SAE2	7	174328	173291	C	Protein with a role in accurate meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents
13343	S000003142	ORF	Verified	YGL174W	BUD13	7	174551	175351	W	Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern
13345	S000003141	ORF	Verified	YGL173C	KEM1	7	180119	175533	C	5'-3' exonuclease involved in mRNA decay, evolutionarily conserved component of cytoplasmic processing (P) bodies, plays a role in microtubule-mediated processes, filamentous growth, and ribosomal RNA maturation
13347	S000003140	ORF	Verified	YGL172W	NUP49	7	180706	182124	W	Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes
13349	S000003139	ORF	Verified	YGL171W	ROK1	7	182396	184090	W	ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis
13351	S000003138	ORF	Verified	YGL170C	SPO74	7	185400	184159	C	Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation
13353	S000006622	tRNA	n.a.	tK(CUU)G2	n.a.	7	185792	185720	C	tRNA-Lys
13355	S000003137	ORF	Verified	YGL169W	SUA5	7	186065	187345	W	Protein required for respiratory growth; null mutation suppresses the Cyc1p translation defect caused by the presence of an aberrant ATG codon upstream of the correct start
13357	S000003136	ORF	Uncharacterized	YGL168W	HUR1	7	187470	187802	W	Protein required for hydroxyurea resistance; has a possible role in DNA replication
13359	S000003135	ORF	Verified	YGL167C	PMR1	7	190474	187622	C	High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease
13361	S000003134	ORF	Verified	YGL166W	CUP2	7	191135	191812	W	Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations
13363	S000003133	ORF	Dubious	YGL165C	n.a.	7	191982	191404	C	Hypothetical protein
13365	S000003132	ORF	Verified	YGL164C	YRB30	7	193306	191984	C	Competes with yeast RanBP1 (Yrb1p) for binding to the GTP-bound form of yeast Ran (Gsp1p); able to form trimeric complexes with RanGTP and some of the karyopherins; inhibits RanGAP1(Rna1p)-mediated GTP hydrolysis on Ran.
13367	S000003131	ORF	Verified	YGL163C	RAD54	7	196409	193713	C	DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family
13369	S000003130	ORF	Verified	YGL162W	SUT1	7	198144	199043	W	Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression
13371	S000003129	ORF	Verified	YGL161C	YIP5	7	200148	199216	C	Protein that interacts with Rab GTPases; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport
13373	S000003128	ORF	Uncharacterized	YGL160W	n.a.	7	200567	202279	W	Hypothetical protein
13375	S000003127	ORF	Uncharacterized	YGL159W	n.a.	7	202727	203839	W	Hypothetical protein
13378	S000006639	tRNA	n.a.	tL(CAA)G1	n.a.	7	205527	205640	W	tRNA-Leu
13379	S000034236	intron	n.a.	n.a.	n.a.	7	205565	205596	W	n.a.
13382	S000003126	ORF	Verified	YGL158W	RCK1	7	207038	208576	W	Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations
13384	S000003125	ORF	Verified	YGL157W	n.a.	7	209011	210054	W	Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
13386	S000003124	ORF	Verified	YGL156W	AMS1	7	210421	213672	W	Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway
13388	S000003123	ORF	Verified	YGL155W	CDC43	7	214086	215216	W	Beta subunit of geranylgeranyltransferase type I, catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis
13390	S000003122	ORF	Verified	YGL154C	LYS5	7	216101	215283	C	Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine
13392	S000003121	ORF	Verified	YGL153W	PEX14	7	216278	217303	W	Peroxisomal membrane protein that is a central component of the peroxisomal protein import machinery, interacts with PTS1 (Pex5p) and PTS2 (Pex7p) peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p
13394	S000003120	ORF	Dubious	YGL152C	n.a.	7	217374	216697	C	Hypothetical protein
13396	S000003119	ORF	Verified	YGL151W	NUT1	7	217529	220927	W	Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription
13398	S000003117	ORF	Dubious	YGL149W	n.a.	7	225577	225882	W	Hypothetical protein
13400	S000003118	ORF	Verified	YGL150C	INO80	7	225578	221109	C	ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases
13402	S000003116	ORF	Verified	YGL148W	ARO2	7	226404	227534	W	Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids
13404	S000003115	ORF	Verified	YGL147C	RPL9A	7	228334	227759	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins
13406	S000003114	ORF	Uncharacterized	YGL146C	n.a.	7	229691	228756	C	Hypothetical protein
13408	S000003113	ORF	Verified	YGL145W	TIP20	7	230248	232353	W	Peripheral membrane protein required for fusion of COPI vesicles with the ER, prohibits back-fusion of COPII vesicles with the ER, may act as a sensor for vesicles at the ER membrane
13411	S000003112	ORF	Verified	YGL144C	ROG1	7	234512	232455	C	Protein with putative serine active lipase domain
13413	S000003111	ORF	Verified	YGL143C	MRF1	7	235963	234722	C	Mitochondrial polypeptide chain release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability
13415	S000003110	ORF	Verified	YGL142C	GPI10	7	238124	236274	C	Integral membrane protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the GPI core structure; human PIG-Bp is a functional homolog
13417	S000003109	ORF	Verified	YGL141W	HUL5	7	238358	241090	W	Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability
13419	S000003108	ORF	Uncharacterized	YGL140C	n.a.	7	245017	241358	C	Hypothetical protein
13421	S000003107	ORF	Uncharacterized	YGL139W	n.a.	7	245721	248129	W	Hypothetical protein
13423	S000003106	ORF	Uncharacterized	YGL138C	n.a.	7	249536	248499	C	Hypothetical protein
13425	S000003105	ORF	Verified	YGL137W	SEC27	7	249874	252743	W	Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP
13428	S000035923	intron	n.a.	n.a.	n.a.	7	249892	250091	W	n.a.
13429	S000003104	ORF	Verified	YGL136C	MRM2	7	253864	252902	C	Mitochondrial 21S rRNA methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ
13431	S000003103	ORF	Verified	YGL135W	RPL1B	7	254646	255299	W	N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal
13433	S000003102	ORF	Verified	YGL134W	PCL10	7	255668	256969	W	Pho85p cyclin; recruits, activates, and targets Pho85p cyclin-dependent protein kinase to its substrate
13435	S000003101	ORF	Verified	YGL133W	ITC1	7	257712	261506	W	Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1
13437	S000003100	ORF	Dubious	YGL132W	n.a.	7	261585	261920	W	Hypothetical protein
13439	S000003099	ORF	Verified	YGL131C	SNT2	7	265864	261653	C	DNA binding protein with similarity to the S. pombe Snt2 protein
13441	S000003098	ORF	Verified	YGL130W	CEG1	7	266150	267529	W	mRNA guanylyltransferase (mRNA capping enzyme), alpha subunit; involved in the synthesis of the cap structure found at the 5'-end of mRNAs
13443	S000003097	ORF	Verified	YGL129C	RSM23	7	269194	267728	C	Mitochondrial ribosomal protein of the small subunit, has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p
13445	S000003096	ORF	Verified	YGL128C	CWC23	7	270150	269299	C	Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to E. coli DnaJ and other DnaJ-like proteins and to S. pombe Cwf23p
13447	S000003095	ORF	Verified	YGL127C	SOH1	7	270781	270398	C	Protein with sequence similarity to RNA polymerases; interacts with a DNA repair protein, Rad5p, in the two-hybrid system; may provide a link between recombination in direct repeats and transcription
13449	S000003094	ORF	Verified	YGL126W	SCS3	7	271003	272145	W	Protein required for inositol prototrophy, appears to be involved in the synthesis of inositol phospholipids from inositol but not in the control of inositol synthesis
13451	S000003093	ORF	Verified	YGL125W	MET13	7	272526	274328	W	Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
13453	S000003092	ORF	Verified	YGL124C	MON1	7	276720	274786	C	Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate
13455	S000003091	ORF	Verified	YGL123W	RPS2	7	277623	278387	W	Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins
13457	S000028634	ORF	Dubious	YGL123C-A	n.a.	7	277870	277640	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13459	S000003090	ORF	Verified	YGL122C	NAB2	7	280529	278952	C	Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export
13461	S000003089	ORF	Verified	YGL121C	GPG1	7	281163	280783	C	Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Grp1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p
13463	S000003088	ORF	Verified	YGL120C	PRP43	7	283943	281640	C	RNA helicase in the DEAH-box family, involved in release of the lariat-intron from the spliceosome
13465	S000003087	ORF	Verified	YGL119W	ABC1	7	284448	285953	W	Protein required for ubiquinone (coenzyme Q) biosynthesis, which in turn is required for respiratory growth; has similarity to prokaryotic proteins involved in early steps of ubiquinone biosynthesis
13467	S000006771	tRNA	n.a.	tW(CCA)G1	n.a.	7	287461	287356	C	tRNA-Trp
13468	S000032524	intron	n.a.	n.a.	n.a.	7	287425	287392	C	n.a.
13471	S000003086	ORF	Dubious	YGL118C	n.a.	7	288457	288020	C	Hypothetical protein
13473	S000003085	ORF	Uncharacterized	YGL117W	n.a.	7	288518	289315	W	Hypothetical protein
13475	S000003084	ORF	Verified	YGL116W	CDC20	7	289812	291644	W	Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate
13477	S000003083	ORF	Verified	YGL115W	SNF4	7	292036	293004	W	Protein kinase activator found in a complex containing Snf1p and members of the Sip1p/Sip2p/Gal83p family; activates the Snf1p protein kinase; involved in expression of glucose-repressed genes, sporulation, and peroxisome biogenesis
13479	S000003082	ORF	Uncharacterized	YGL114W	n.a.	7	293463	295640	W	Putative member of the oligopeptide transporter (OPT) family of membrane transporters
13481	S000003081	ORF	Verified	YGL113W	SLD3	7	295935	297941	W	Protein involved in the initiation of DNA replication, required for proper assembly of replication proteins at the origins of replication; interacts with Cdc45p
13483	S000003080	ORF	Verified	YGL112C	TAF6	7	299731	298181	C	Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4
13485	S000003079	ORF	Verified	YGL111W	NSA1	7	299981	301372	W	Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis
13487	S000003078	ORF	Uncharacterized	YGL110C	CUE3	7	303414	301540	C	Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination
13489	S000003077	ORF	Dubious	YGL109W	n.a.	7	303516	303839	W	Hypothetical protein
13491	S000003076	ORF	Uncharacterized	YGL108C	n.a.	7	304074	303652	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
13493	S000003075	ORF	Verified	YGL107C	RMD9	7	306276	304336	C	Mitochondrial protein required for sporulation
13495	S000003074	ORF	Verified	YGL106W	MLC1	7	306563	307012	W	Essential light chain for myosin Myo2p; may stabilize Myo2p by binding to the neck region; may interact with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition
13497	S000003073	ORF	Verified	YGL105W	ARC1	7	307440	308570	W	Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids
13499	S000003072	ORF	Verified	YGL104C	VPS73	7	310176	308716	C	Mitochondrial protein of unknown function involved in vacuolar protein sorting
13501	S000003071	ORF	Verified	YGL103W	RPL28	7	310970	311930	W	Ribosomal protein L29 of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a ribosomal proteins; may have peptidyl transferase activity; can mutate to cycloheximide resistance
13504	S000032090	intron	n.a.	n.a.	n.a.	7	311019	311529	W	n.a.
13505	S000003070	ORF	Dubious	YGL102C	n.a.	7	311936	311508	C	Protein required for cell viability
13507	S000003069	ORF	Uncharacterized	YGL101W	n.a.	7	312196	312843	W	Hypothetical protein
13509	S000003068	ORF	Verified	YGL100W	SEH1	7	313237	314286	W	Nuclear pore protein that is part of the evolutionarily conserved Nup84p complex (Nup84p, Nup85p, Nup120p, Nup145p, and Seh1p); homologous to Sec13p
13511	S000003067	ORF	Verified	YGL099W	LSG1	7	314634	316556	W	Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm
13513	S000028467	snoRNA	n.a.	snR82	SNR82	7	316791	317058	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at positions 2348 and 2350
13515	S000003066	ORF	Verified	YGL098W	USE1	7	317345	318082	W	Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p
13520	S000006596	tRNA	n.a.	tH(GUG)G2	n.a.	7	319784	319855	W	tRNA-His
13523	S000003065	ORF	Verified	YGL097W	SRM1	7	321785	323233	W	Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; potentially phosphorylated by Cdc28p
13525	S000003064	ORF	Verified	YGL096W	TOS8	7	325334	326164	W	Homeodomain-containing transcription factor; SBF regulated target gene that in turn regulates expression of genes involved in G1/S phase events such as bud site selection, bud emergence and cell cycle progression; similarity to Cup9p
13528	S000006553	tRNA	n.a.	tE(UUC)G1	SOE1	7	328586	328657	W	tRNA-Glu
13530	S000003063	ORF	Verified	YGL095C	VPS45	7	330610	328877	C	Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment
13532	S000003062	ORF	Verified	YGL094C	PAN2	7	334468	331121	C	Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes
13534	S000003061	ORF	Verified	YGL093W	SPC105	7	334889	337642	W	Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp
13536	S000003060	ORF	Verified	YGL092W	NUP145	7	337909	341862	W	Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that assembles into the Nup84p subcomplex of the nuclear pore complex, and an N-terminal fragment of unknown function that is homologous to Nup100p
13538	S000003059	ORF	Verified	YGL091C	NBP35	7	343045	342059	C	Essential nuclear protein, evolutionarily conserved putative ATPase; exhibits genetic interaction with CDC2 encoding the catalytic subunit of DNA polymerase delta
13540	S000003058	ORF	Verified	YGL090W	LIF1	7	343322	344587	W	Protein involved in DNA double-strand break repair; physically interacts with DNA ligase 4 (Lig4p); homologous to mammalian XRCC4 protein
13542	S000003057	ORF	Verified	YGL089C	MF(ALPHA)2	7	345156	344794	C	Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2
13544	S000003056	ORF	Dubious	YGL088W	n.a.	7	345839	346204	W	Hypothetical protein
13546	S000007499	snoRNA	n.a.	snR10	SNR10	7	345989	346233	W	H/ACA small nucleolar RNA (snoRNA); essential gene required for preRNA processing for cleavage at sites A1 and A2; guides pseudouridylation of large subunit rRNA at position 2919
13548	S000003055	ORF	Verified	YGL087C	MMS2	7	346907	346409	C	Protein involved in error-free postreplication DNA repair; forms a heteromeric complex with Ubc13p that has a ubiquitin-conjugating activity; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p
13551	S000036107	intron	n.a.	n.a.	n.a.	7	346896	346812	C	n.a.
13552	S000003054	ORF	Verified	YGL086W	MAD1	7	347122	349371	W	Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p
13554	S000003053	ORF	Uncharacterized	YGL085W	n.a.	7	349619	350443	W	Hypothetical protein
13556	S000003052	ORF	Verified	YGL084C	GUP1	7	352301	350619	C	Plasma membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases
13558	S000003051	ORF	Verified	YGL083W	SCY1	7	353061	355475	W	Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase
13560	S000003050	ORF	Uncharacterized	YGL082W	n.a.	7	355830	356975	W	Hypothetical protein
13562	S000003049	ORF	Uncharacterized	YGL081W	n.a.	7	357380	358342	W	Hypothetical protein
13564	S000003048	ORF	Uncharacterized	YGL080W	n.a.	7	358639	359031	W	The authentic, non-tagged protein was localized to the mitochondria
13566	S000003047	ORF	Uncharacterized	YGL079W	n.a.	7	359447	360103	W	Hypothetical protein
13568	S000003046	ORF	Verified	YGL078C	DBP3	7	361862	360291	C	Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis
13570	S000003045	ORF	Verified	YGL077C	HNM1	7	363919	362228	C	Choline transporter (permease) that also controls the uptake of nitrogen mustard; expression is co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol
13572	S000007302	snoRNA	n.a.	snR39	SNR39	7	365254	365166	C	Small nucleolar RNA
13574	S000003044	ORF	Verified	YGL076C	RPL7A	7	365999	364338	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)
13578	S000032067	intron	n.a.	n.a.	n.a.	7	365435	364968	C	n.a.
13579	S000032066	intron	n.a.	n.a.	n.a.	7	365988	365530	C	n.a.
13580	S000007303	snoRNA	n.a.	snR39B	SNR39B	7	366472	366377	C	Small nucleolar RNA
13582	S000003043	ORF	Verified	YGL075C	MPS2	7	368091	366928	C	Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required for insertion of the newly duplicated SPB into the nuclear envelope; potentially phosphorylated by Cdc28p
13584	S000003041	ORF	Verified	YGL073W	HSF1	7	368756	371257	W	Trimeric heat shock transcription factor, activates multiple genes in response to hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; constitutively DNA-bound; posttranslationally regulated
13586	S000003042	ORF	Dubious	YGL074C	n.a.	7	368925	368599	C	Protein required for cell viability
13588	S000003040	ORF	Dubious	YGL072C	n.a.	7	371365	371006	C	Hypothetical protein
13590	S000003039	ORF	Verified	YGL071W	RCS1	7	372015	374087	W	Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability
13592	S000003038	ORF	Verified	YGL070C	RPB9	7	374830	374462	C	RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site
13594	S000003036	ORF	Verified	YGL068W	MNP1	7	375090	375674	W	Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7/L12 ribosomal protein; required for normal respiratory growth
13596	S000003037	ORF	Dubious	YGL069C	n.a.	7	375517	375053	C	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; 92% of ORF overlaps the uncharacterized ORF YGL068W; deletion in cyr1 mutant results in loss of stress resistance
13598	S000003035	ORF	Verified	YGL067W	NPY1	7	376104	377258	W	NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes
13600	S000003034	ORF	Verified	YGL066W	SGF73	7	377612	379585	W	Probable 73 kDa subunit of SAGA histone acetyltransferase complex
13602	S000003033	ORF	Verified	YGL065C	ALG2	7	381274	379763	C	Presumed early mannosyltransferase involved in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol
13604	S000003032	ORF	Verified	YGL064C	MRH4	7	383211	381526	C	Mitochondrial RNA helicase, plays an essential role in mitochondrial function
13606	S000003031	ORF	Verified	YGL063W	PUS2	7	383657	384769	W	Putative pseudouridine synthase
13608	S000028633	ORF	Dubious	YGL063C-A	n.a.	7	384654	384505	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13610	S000003030	ORF	Verified	YGL062W	PYC1	7	385199	388735	W	Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis
13612	S000003029	ORF	Verified	YGL061C	DUO1	7	389714	388971	C	Essential mitotic spindle protein required to maintain spindle integrity and kinetochore function, part of the multisubunit DASH complex which binds microtubules and is transferred to the kinetochore prior to mitosis
13614	S000003028	ORF	Verified	YGL060W	YBP2	7	390070	391995	W	Protein with a role in resistance to oxidative stress; has similarity to Ybp1p, which is involved in regulation of the transcription factor Yap1p via oxidation of specific cysteine residues
13616	S000003027	ORF	Uncharacterized	YGL059W	n.a.	7	392228	393703	W	Hypothetical protein
13618	S000003026	ORF	Verified	YGL058W	RAD6	7	393992	394510	W	Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)
13620	S000003025	ORF	Uncharacterized	YGL057C	n.a.	7	395835	394972	C	Hypothetical protein
13622	S000003024	ORF	Verified	YGL056C	SDS23	7	397624	396041	C	One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC/cyclosome regulation
13624	S000003023	ORF	Verified	YGL055W	OLE1	7	398631	400163	W	Fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria
13626	S000003022	ORF	Verified	YGL054C	ERV14	7	401290	400874	C	Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon
13628	S000006554	tRNA	n.a.	tE(UUC)G2	n.a.	7	401601	401530	C	tRNA-Glu
13632	S000003021	ORF	Verified	YGL053W	PRM8	7	402592	403305	W	Pheromone-regulated protein with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER
13634	S000003020	ORF	Dubious	YGL052W	n.a.	7	403440	403745	W	Hypothetical protein
13636	S000003019	ORF	Verified	YGL051W	MST27	7	403690	404394	W	Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles
13641	S000006711	tRNA	n.a.	tR(UCU)G1	n.a.	7	405473	405544	W	tRNA-Arg
13643	S000003018	ORF	Uncharacterized	YGL050W	n.a.	7	405779	406600	W	Hypothetical protein
13645	S000003017	ORF	Verified	YGL049C	TIF4632	7	409607	406863	C	Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p
13647	S000003016	ORF	Verified	YGL048C	RPT6	7	411289	410072	C	One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle
13649	S000003015	ORF	Verified	YGL047W	ALG13	7	411555	412163	W	Essential protein required for the second step of dolichyl-linked oligosaccharide synthesis; involved in N-linked glycosylation; similar to bacterial glycosyltransferases
13651	S000006755	tRNA	n.a.	tV(AAC)G1	n.a.	7	412370	412297	C	tRNA-Val
13654	S000003013	ORF	Verified	YGL045W	RIM8	7	414106	415734	W	Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalF
13656	S000003012	ORF	Verified	YGL044C	RNA15	7	417040	416150	C	Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p
13658	S000003011	ORF	Verified	YGL043W	DST1	7	417487	418416	W	General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites
13660	S000003010	ORF	Dubious	YGL042C	n.a.	7	418597	418292	C	Dubious open reading frame, not conserved in closely related Saccharomyces species; deletion mutation blocks replication of Brome mosaic virus in S. cerevisiae, but this is likely due to effects on the overlapping gene DST1
13662	S000028548	ORF	Uncharacterized	YGL041C-B	n.a.	7	418891	418709	C	Identified by fungal homology and RT-PCR
13664	S000028826	ORF	Dubious	YGL041W-A	n.a.	7	419047	419295	W	Identified by expression profiling and mass spectrometry
13666	S000003009	ORF	Dubious	YGL041C	n.a.	7	419231	418917	C	Hypothetical protein
13668	S000003008	ORF	Verified	YGL040C	HEM2	7	420561	419533	C	Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus
13670	S000006640	tRNA	n.a.	tL(CAA)G2	SUP54	7	423098	423211	W	tRNA-Leu
13671	S000034245	intron	n.a.	n.a.	n.a.	7	423136	423167	W	n.a.
13674	S000003007	ORF	Verified	YGL039W	n.a.	7	423967	425013	W	Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)
13676	S000003006	ORF	Verified	YGL038C	OCH1	7	426810	425368	C	Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins
13678	S000003005	ORF	Verified	YGL037C	PNC1	7	427953	427303	C	Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span
13680	S000003004	ORF	Uncharacterized	YGL036W	n.a.	7	428606	431335	W	Mtf1 Two Hybrid Clone 2
13682	S000003003	ORF	Verified	YGL035C	MIG1	7	433067	431553	C	Transcription factor involved in glucose repression; C2H2 zinc finger protein similar to mammalian Egr and Wilms tumor proteins
13684	S000003002	ORF	Dubious	YGL034C	n.a.	7	433584	433219	C	Hypothetical protein
13686	S000003001	ORF	Verified	YGL033W	HOP2	7	435630	436356	W	Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair
13689	S000033179	intron	n.a.	n.a.	n.a.	7	435685	435754	W	n.a.
13690	S000003000	ORF	Verified	YGL032C	AGA2	7	436838	436575	C	Adhesion subunit of a-agglutinin of a-cells, C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds
13692	S000002999	ORF	Verified	YGL031C	RPL24A	7	437939	437472	C	Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
13694	S000002998	ORF	Verified	YGL030W	RPL30	7	439096	439643	W	Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript
13697	S000032084	intron	n.a.	n.a.	n.a.	7	439099	439328	W	n.a.
13698	S000002997	ORF	Verified	YGL029W	CGR1	7	440068	440430	W	Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress
13700	S000006565	tRNA	n.a.	tF(GAA)G	n.a.	7	440812	440721	C	tRNA-Phe
13701	S000035389	intron	n.a.	n.a.	n.a.	7	440775	440757	C	n.a.
13704	S000002996	ORF	Verified	YGL028C	SCW11	7	442914	441286	C	Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p
13706	S000002995	ORF	Verified	YGL027C	CWH41	7	446148	443647	C	Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress
13708	S000002994	ORF	Verified	YGL026C	TRP5	7	448540	446417	C	Tryptophan synthase involved in tryptophan biosynthesis, regulated by the general control system of amino acid biosynthesis
13710	S000002992	ORF	Dubious	YGL024W	n.a.	7	449793	450128	W	Protein of unknown function
13712	S000002993	ORF	Verified	YGL025C	PGD1	7	449962	448769	C	Subunit of the Mediator global transcriptional cofactor complex, which is part of the RNA polymerase II holoenzyme and plays an essential role in basal and activated transcription; direct target of the Cyc8p-Tup1p transcriptional corepressor
13714	S000002991	ORF	Verified	YGL023C	PIB2	7	452109	450202	C	Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27
13716	S000002990	ORF	Verified	YGL022W	STT3	7	452409	454565	W	Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis
13718	S000002989	ORF	Verified	YGL021W	ALK1	7	454790	457072	W	Putative Ser-Thr protein kinase, belongs to the haspin family of kinases; contains a leucine zipper motif; may function in mitosis
13720	S000002988	ORF	Verified	YGL020C	MDM39	7	457875	457168	C	Protein required for normal mitochondrial morphology and inheritance
13722	S000002987	ORF	Verified	YGL019W	CKB1	7	458161	458997	W	beta (38kDa) subunit of protein kinase CK2
13724	S000002986	ORF	Verified	YGL018C	JAC1	7	459669	459115	C	Molecular chaperone involved, with partner Ssq1p, in assembly of Fe/S clusters and in mitochondrial iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix
13726	S000002985	ORF	Verified	YGL017W	ATE1	7	459859	461370	W	Arginyl-tRNA-protein transferase, catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway
13728	S000002984	ORF	Verified	YGL016W	KAP122	7	461671	464916	W	Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance
13730	S000002983	ORF	Uncharacterized	YGL015C	n.a.	7	465440	465048	C	Hypothetical protein
13732	S000002982	ORF	Verified	YGL014W	PUF4	7	466146	468812	W	Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors
13734	S000028825	ORF	Dubious	YGL014C-A	n.a.	7	466403	466242	C	Identified by expression profiling and mass spectrometry
13736	S000002981	ORF	Verified	YGL013C	PDR1	7	472303	469097	C	Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes
13738	S000002980	ORF	Verified	YGL012W	ERG4	7	472860	474281	W	C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol
13740	S000002979	ORF	Verified	YGL011C	SCL1	7	475252	474494	C	Alpha subunit of the 20S core complex of the 26S proteasome involved in the degradation of ubiquitinated substrates; essential for growth; detected in the mitochondria
13742	S000002978	ORF	Uncharacterized	YGL010W	n.a.	7	475550	476074	W	Hypothetical protein
13744	S000002977	ORF	Verified	YGL009C	LEU1	7	478657	476318	C	Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway
13746	S000002976	ORF	Verified	YGL008C	PMA1	7	482671	479915	C	Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases
13748	S000028632	ORF	Uncharacterized	YGL007C-A	n.a.	7	483032	482946	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13750	S000002975	ORF	Dubious	YGL007W	n.a.	7	483265	483642	W	Hypothetical protein
13752	S000028769	ORF	Uncharacterized	YGL006W-A	n.a.	7	485428	485538	W	Identified by SAGE
13754	S000002974	ORF	Verified	YGL006W	PMC1	7	485925	489446	W	Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium
13756	S000002973	ORF	Verified	YGL005C	COG7	7	490551	489712	C	Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
13758	S000002972	ORF	Uncharacterized	YGL004C	RPN14	7	491960	490707	C	Putative non-ATPase subunit of the 19S regulatory particle of the 26S proteasome; localized to the cytoplasm
13760	S000002971	ORF	Verified	YGL003C	CDH1	7	494178	492478	C	CDC20 homolog 1; protein required for Clb2 and Ase1 degradation
13762	S000002970	ORF	Verified	YGL002W	ERP6	7	494521	495171	W	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
13764	S000002969	ORF	Verified	YGL001C	ERG26	7	496506	495457	C	C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis
13770	S000003233	ORF	Uncharacterized	YGR001C	n.a.	7	498038	497137	C	Protein with similarity to methyltransferase family members; required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
13774	S000032875	intron	n.a.	n.a.	n.a.	7	497462	497370	C	n.a.
13775	S000032874	intron	n.a.	n.a.	n.a.	7	498003	497942	C	n.a.
13776	S000003234	ORF	Verified	YGR002C	SWC4	7	499910	498480	C	Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex
13778	S000003235	ORF	Verified	YGR003W	CUL3	7	500136	502370	W	Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; null mutation has no apparent phenotype
13780	S000003236	ORF	Verified	YGR004W	PEX31	7	502942	504330	W	Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p
13782	S000003237	ORF	Verified	YGR005C	TFG2	7	505863	504661	C	transcription initiation factor TFIIF middle subunit
13784	S000003238	ORF	Verified	YGR006W	PRP18	7	506074	506829	W	Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, recruited to the spliceosome by Slu7p
13786	S000003239	ORF	Verified	YGR007W	MUQ1	7	506973	507944	W	Choline phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases
13788	S000003240	ORF	Verified	YGR008C	STF2	7	508368	508114	C	Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p act as stabilizing factors that enhance inhibitory action of the Inh1p protein
13790	S000003241	ORF	Verified	YGR009C	SEC9	7	511006	509051	C	t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but not functionally redundant with Spo20p; SNAP-25 homolog
13792	S000003242	ORF	Verified	YGR010W	NMA2	7	511549	512736	W	Nicotinic acid mononucleotide adenylyltransferase, involved in NAD(+) salvage pathway
13794	S000003243	ORF	Dubious	YGR011W	n.a.	7	512501	512827	W	Hypothetical protein
13796	S000003244	ORF	Uncharacterized	YGR012W	n.a.	7	513163	514344	W	Hypothetical protein
13798	S000003245	ORF	Verified	YGR013W	SNU71	7	514558	516420	W	associated with U1 snRNP (no counterpart in mammalian U1 snRNP; contains few SR-, RE- and RD-dipeptides; U1 snRNP protein
13800	S000003246	ORF	Verified	YGR014W	MSB2	7	516947	520867	W	Mucin family member at the head of the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate
13802	S000003247	ORF	Uncharacterized	YGR015C	n.a.	7	522080	521094	C	Hypothetical protein
13804	S000003248	ORF	Uncharacterized	YGR016W	n.a.	7	522265	522837	W	Hypothetical protein
13806	S000003249	ORF	Uncharacterized	YGR017W	n.a.	7	523791	524684	W	Hypothetical protein
13808	S000003250	ORF	Dubious	YGR018C	n.a.	7	524698	524369	C	Hypothetical protein
13810	S000003251	ORF	Verified	YGR019W	UGA1	7	525233	526648	W	Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization
13812	S000003252	ORF	Verified	YGR020C	VMA7	7	527333	526977	C	Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane
13814	S000003253	ORF	Uncharacterized	YGR021W	n.a.	7	527636	528508	W	Hypothetical protein
13816	S000003255	ORF	Verified	YGR023W	MTL1	7	529268	530923	W	Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations
13818	S000003254	ORF	Dubious	YGR022C	n.a.	7	529590	529261	C	Hypothetical protein
13820	S000006532	tRNA	n.a.	tD(GUC)G1	n.a.	7	531614	531685	W	tRNA-Asp
13822	S000003256	ORF	Verified	YGR024C	THG1	7	532600	531887	C	tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes
13824	S000003257	ORF	Dubious	YGR025W	n.a.	7	532643	532945	W	Hypothetical protein
13826	S000003258	ORF	Uncharacterized	YGR026W	n.a.	7	532989	533825	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
13828	S000003259	ORF	Verified	YGR027C	RPS25A	7	534462	534136	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein
13841	S000006555	tRNA	n.a.	tE(UUC)G3	n.a.	7	541854	541925	W	tRNA-Glu
13843	S000003260	ORF	Verified	YGR028W	MSP1	7	542207	543295	W	Mitochondrial protein involved in sorting of proteins in the mitochondria; putative membrane-spanning ATPase
13845	S000003261	ORF	Verified	YGR029W	ERV1	7	543557	544209	W	Flavin-linked sulfhydryl oxidase localized to the mitochondrial intermembrane space, has a role in the maturation of cytosolic iron-sulfur proteins; ortholog of human hepatopoietin (ALR)
13848	S000035765	intron	n.a.	n.a.	n.a.	7	543643	543725	W	n.a.
13849	S000006533	tRNA	n.a.	tD(GUC)G2	n.a.	7	544652	544581	C	tRNA-Asp
13851	S000006506	snoRNA	n.a.	snR46	SNR46	7	545373	545569	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2861
13853	S000003262	ORF	Verified	YGR030C	POP6	7	546161	545685	C	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
13855	S000003263	ORF	Uncharacterized	YGR031W	n.a.	7	546445	547473	W	Hypothetical protein
13857	S000028636	ORF	Dubious	YGR031C-A	n.a.	7	547304	546813	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13859	S000003264	ORF	Verified	YGR032W	GSC2	7	548268	553955	W	Catalytic subunit of 1,3-beta-glucan synthase, has similarity to an alternate catalytic subunit, Fks1p (Gsc1p); Rho1p encodes the regulatory subunit; involved in cell wall synthesis and maintenance
13861	S000003265	ORF	Verified	YGR033C	TIM21	7	554971	554252	C	Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may regulate protein import by binding to both the translocase of the outer membrane (TOM) and presequence-associated motor (PAM) complexes
13863	S000003266	ORF	Verified	YGR034W	RPL26B	7	555933	556676	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA
13866	S000037474	intron	n.a.	n.a.	n.a.	7	555958	556311	W	n.a.
13867	S000003267	ORF	Uncharacterized	YGR035C	n.a.	7	557426	557076	C	Protein of unknown function, potential Cdc28p substrate; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance
13869	S000028827	ORF	Uncharacterized	YGR035W-A	n.a.	7	557569	557790	W	Identified by expression profiling and mass spectrometry
13871	S000003268	ORF	Verified	YGR036C	CAX4	7	558872	558153	C	Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation
13873	S000003269	ORF	Verified	YGR037C	ACB1	7	559998	559735	C	Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes
13875	S000003270	ORF	Verified	YGR038W	ORM1	7	560686	561354	W	Evolutionarily conserved protein with similarity to Orm2p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum
13877	S000006725	tRNA	n.a.	tS(AGA)G	n.a.	7	561747	561666	C	tRNA-Ser
13891	S000003271	ORF	Dubious	YGR039W	n.a.	7	574892	575203	W	Hypothetical protein
13893	S000003272	ORF	Verified	YGR040W	KSS1	7	575402	576508	W	Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response
13895	S000003273	ORF	Verified	YGR041W	BUD9	7	577491	579134	W	Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole
13897	S000003274	ORF	Uncharacterized	YGR042W	n.a.	7	579480	580295	W	Hypothetical protein
13899	S000003275	ORF	Uncharacterized	YGR043C	n.a.	7	581440	580439	C	Hypothetical protein
13901	S000003276	ORF	Verified	YGR044C	RME1	7	583896	582994	C	Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation
13903	S000003277	ORF	Uncharacterized	YGR045C	n.a.	7	584300	583938	C	Hypothetical protein
13905	S000003278	ORF	Uncharacterized	YGR046W	n.a.	7	584899	586056	W	Essential protein of unknown function, mRNA is targeted to the bud via the mRNA transport system involving She2p
13907	S000003279	ORF	Verified	YGR047C	TFC4	7	589473	586396	C	One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102
13909	S000003280	ORF	Verified	YGR048W	UFD1	7	589830	590915	W	Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol
13911	S000003281	ORF	Verified	YGR049W	SCM4	7	591318	591881	W	Potential regulatory effector of CDC4 function, suppresses a temperature-sensitive allele of CDC4, tripartite protein structure in which a charged region separates two uncharged domains, not essential for mitosis or meiosis
13913	S000003282	ORF	Dubious	YGR050C	n.a.	7	592446	592090	C	Hypothetical protein
13915	S000003283	ORF	Dubious	YGR051C	n.a.	7	593233	592910	C	Hypothetical protein
13917	S000003284	ORF	Uncharacterized	YGR052W	n.a.	7	593600	594709	W	The authentic, non-tagged protein was localized to the mitochondria
13919	S000003285	ORF	Uncharacterized	YGR053C	n.a.	7	595841	594990	C	Hypothetical protein
13921	S000003286	ORF	Uncharacterized	YGR054W	n.a.	7	596697	598625	W	yeast homolog of mammalian eIF2A
13923	S000003287	ORF	Verified	YGR055W	MUP1	7	599421	601145	W	High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake
13925	S000003288	ORF	Verified	YGR056W	RSC1	7	601665	604451	W	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; required for expression of mid-late sporulation-specific genes; contains two essential  bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook
13927	S000003289	ORF	Verified	YGR057C	LST7	7	605505	604777	C	Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface
13929	S000003290	ORF	Uncharacterized	YGR058W	n.a.	7	606140	607147	W	Hypothetical protein
13931	S000003291	ORF	Verified	YGR059W	SPR3	7	607567	609105	W	a sporulation-specific homologue of the yeast CDC3/10/11/12 family of bud neck microfilament genes; regulated by ABFI; septin protein involved in sporulation
13933	S000006440	snoRNA	n.a.	snR48	SNR48	7	609588	609700	W	guides 2'-O-methylation on large subunit rRNA at G2788 and G2790; small nucleolar RNA snR48
13935	S000003292	ORF	Verified	YGR060W	ERG25	7	610568	611497	W	C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol
13937	S000003293	ORF	Verified	YGR061C	ADE6	7	615969	611893	C	Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway
13939	S000003294	ORF	Verified	YGR062C	COX18	7	617282	616332	C	Mitochondrial inner membrane protein, required for export of the Cox2p C terminus from the mitochondrial matrix to the intermembrane space during its assembly into cytochrome c oxidase; similar to Oxa2p of N. crassa
13941	S000003296	ORF	Dubious	YGR064W	n.a.	7	617625	617993	W	Hypothetical protein
13943	S000003295	ORF	Verified	YGR063C	SPT4	7	617828	617520	C	Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing
13945	S000003297	ORF	Verified	YGR065C	VHT1	7	619862	618081	C	High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin
13947	S000003298	ORF	Uncharacterized	YGR066C	n.a.	7	621803	620925	C	Hypothetical protein
13949	S000003299	ORF	Uncharacterized	YGR067C	n.a.	7	624790	622406	C	Hypothetical protein; has similarity to Adr1p DNA-binding domain
13951	S000028637	ORF	Dubious	YGR068W-A	n.a.	7	626298	626393	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
13953	S000003301	ORF	Dubious	YGR069W	n.a.	7	627087	627422	W	Hypothetical protein
13955	S000003300	ORF	Uncharacterized	YGR068C	n.a.	7	627088	625328	C	Hypothetical protein
13957	S000003302	ORF	Verified	YGR070W	ROM1	7	627810	631277	W	GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP
13959	S000003303	ORF	Uncharacterized	YGR071C	n.a.	7	634067	631485	C	Hypothetical protein
13961	S000003304	ORF	Verified	YGR072W	UPF3	7	634308	635471	W	Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p and Nmd2p; involved in decay of mRNA containing nonsense codons
13963	S000003306	ORF	Verified	YGR074W	SMD1	7	635716	636156	W	Homolog of human core snRNP protein D1, involved in snRNA maturation; U6 snRNP protein
13965	S000003305	ORF	Dubious	YGR073C	n.a.	7	635990	635619	C	Protein required for cell viability
13967	S000003307	ORF	Verified	YGR075C	PRP38	7	636879	636151	C	Unique component of the U4/U6.U5 tri-snRNP particle, dispensable for spliceosome assembly, but required for conformational changes which lead to catalytic activation of the spliceosome
13969	S000003308	ORF	Verified	YGR076C	MRPL25	7	637581	637108	C	Mitochondrial ribosomal protein of the large subunit
13971	S000003309	ORF	Verified	YGR077C	PEX8	7	639517	637748	C	Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5p
13973	S000003310	ORF	Verified	YGR078C	PAC10	7	640375	639776	C	Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding
13975	S000003311	ORF	Uncharacterized	YGR079W	n.a.	7	640724	641836	W	Hypothetical protein
13977	S000003312	ORF	Verified	YGR080W	TWF1	7	642014	643012	W	Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly
13979	S000003313	ORF	Verified	YGR081C	SLX9	7	643784	643152	C	Protein of unknown function; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant
13981	S000003314	ORF	Verified	YGR082W	TOM20	7	644048	644599	W	Translocase of Outer Mitochondrial membrane; 20 kDa mitochondrial outer membrane protein import receptor
13983	S000003315	ORF	Verified	YGR083C	GCD2	7	646819	644864	C	Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression
13985	S000003316	ORF	Verified	YGR084C	MRP13	7	648146	647127	C	Mitochondrial ribosomal protein of the small subunit
13987	S000003317	ORF	Verified	YGR085C	RPL11B	7	648911	648387	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11
13989	S000003318	ORF	Verified	YGR086C	PIL1	7	650621	649602	C	Long chain base-responsive inhibitor of protein kinases Phk1p and Phk2p, acts along with Lsp1p to down-regulate heat stress resistance via regulation of the Pkc1p and Ypk1p pathways; phosphorylated by Phk1p and Phk2p
13991	S000003319	ORF	Verified	YGR087C	PDC6	7	652985	651294	C	Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, involved in amino acid catabolism
13993	S000003320	ORF	Verified	YGR088W	CTT1	7	654605	656326	W	Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide
13995	S000003321	ORF	Uncharacterized	YGR089W	NNF2	7	656964	659774	W	Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation
13997	S000006749	tRNA	n.a.	tT(UGU)G1	n.a.	7	661753	661824	W	tRNA-Thr
13999	S000003322	ORF	Uncharacterized	YGR090W	UTP22	7	662362	666075	W	Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data
14001	S000003323	ORF	Verified	YGR091W	PRP31	7	666345	667829	W	Splicing factor, component of the U4/U6-U5 snRNP complex
14003	S000003324	ORF	Verified	YGR092W	DBF2	7	668193	669911	W	Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis
14005	S000003325	ORF	Uncharacterized	YGR093W	n.a.	7	670392	671915	W	Hypothetical protein
14007	S000003326	ORF	Verified	YGR094W	VAS1	7	672190	675504	W	Mitochondrial and cytoplasmic valyl-tRNA synthetase
14009	S000003327	ORF	Verified	YGR095C	RRP46	7	676346	675675	C	Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex
14011	S000003328	ORF	Verified	YGR096W	TPC1	7	676625	677569	W	Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family
14013	S000003329	ORF	Verified	YGR097W	ASK10	7	678699	682139	W	Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes
14015	S000003330	ORF	Verified	YGR098C	ESP1	7	687462	682570	C	Separase with cysteine protease activity (related to caspases) that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibited by Pds1p
14017	S000003331	ORF	Verified	YGR099W	TEL2	7	687903	689969	W	Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect
14019	S000003332	ORF	Verified	YGR100W	MDR1	7	690249	693101	W	Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function
14021	S000003333	ORF	Verified	YGR101W	PCP1	7	693367	694407	W	Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases
14023	S000003334	ORF	Uncharacterized	YGR102C	n.a.	7	695139	694588	C	Hypothetical protein
14025	S000003335	ORF	Verified	YGR103W	NOP7	7	695421	697238	W	Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles
14027	S000003336	ORF	Verified	YGR104C	SRB5	7	698372	697449	C	subunit of RNA polymerase II holoenzyme/mediator complex
14029	S000003337	ORF	Verified	YGR105W	VMA21	7	698603	698836	W	Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)
14031	S000003338	ORF	Uncharacterized	YGR106C	n.a.	7	699790	698993	C	Hypothetical protein
14033	S000006646	tRNA	n.a.	tL(GAG)G	n.a.	7	700679	700760	W	tRNA-Leu
14035	S000006631	tRNA	n.a.	tK(UUU)G2	n.a.	7	701052	700957	C	tRNA-Lys
14036	S000033693	intron	n.a.	n.a.	n.a.	7	701015	700993	C	n.a.
14040	S000003339	ORF	Dubious	YGR107W	n.a.	7	702671	703120	W	Hypothetical protein
14042	S000003340	ORF	Verified	YGR108W	CLB1	7	703640	705055	W	B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome
14044	S000003341	ORF	Verified	YGR109C	CLB6	7	706505	705363	C	B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1
14046	S000006527	tRNA	n.a.	tC(GCA)G	n.a.	7	707183	707112	C	tRNA-Cys
14058	S000003342	ORF	Uncharacterized	YGR110W	n.a.	7	713713	715050	W	Hypothetical protein
14060	S000003343	ORF	Uncharacterized	YGR111W	n.a.	7	715832	717034	W	Hypothetical protein
14062	S000003344	ORF	Verified	YGR112W	SHY1	7	717362	718531	W	Mitochondrial inner membrane protein required for normal respiration, possible chaperone involved in assembly of cytochrome c oxidase; similar to SURF1 from mammals, chickens, and D. melanogaster
14064	S000003345	ORF	Verified	YGR113W	DAM1	7	718897	719928	W	Component of the DASH complex, localized to intranuclear spindles and spindle pole bodies; interacts with Duo1p and Mps1p; key Ipl1p target for regulating kinetochore-microtubule attachments
14066	S000003348	ORF	Verified	YGR116W	SPT6	7	720413	724768	W	Essential protein that interacts with histones and is involved in nucleosome disassembly and reassembly during transcription elongation
14068	S000003346	ORF	Dubious	YGR114C	n.a.	7	720658	720269	C	Protein required for cell viability
14070	S000003347	ORF	Dubious	YGR115C	n.a.	7	721155	720376	C	Protein required for cell viability
14072	S000003349	ORF	Uncharacterized	YGR117C	n.a.	7	726483	725053	C	Hypothetical protein
14074	S000003350	ORF	Verified	YGR118W	RPS23A	7	726978	727735	W	Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal
14077	S000033496	intron	n.a.	n.a.	n.a.	7	727043	727362	W	n.a.
14078	S000003351	ORF	Verified	YGR119C	NUP57	7	729676	728051	C	Essential subunit of the nuclear pore complex (NPC), functions as the organizing center of an NPC subcomplex containing Nsp1p, Nup49p, Nup57p, and Nic96p
14080	S000003352	ORF	Verified	YGR120C	COG2	7	730826	730038	C	Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments
14082	S000006670	tRNA	n.a.	tN(GUU)G	n.a.	7	731142	731215	W	tRNA-Asn
14084	S000003353	ORF	Verified	YGR121C	MEP1	7	732932	731454	C	Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation
14086	S000028550	ORF	Uncharacterized	YGR121W-A	n.a.	7	733417	733632	W	Identified by fungal homology and RT-PCR
14088	S000003354	ORF	Uncharacterized	YGR122W	n.a.	7	733940	735148	W	Hypothetical protein
14091	S000007240	ORF	Dubious	YGR122C-A	n.a.	7	735763	735635	C	Similar to probable membrane protein YLR334C and ORF YOL106W
14094	S000006713	tRNA	n.a.	tR(UCU)G3	n.a.	7	736345	736416	W	tRNA-Arg
14096	S000003355	ORF	Verified	YGR123C	PPT1	7	738208	736667	C	Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth
14098	S000006604	tRNA	n.a.	tI(AAU)G	n.a.	7	739127	739200	W	tRNA-Ile
14100	S000003356	ORF	Verified	YGR124W	ASN2	7	739949	741667	W	Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway
14102	S000003357	ORF	Uncharacterized	YGR125W	n.a.	7	742330	745440	W	Hypothetical protein
14104	S000003358	ORF	Uncharacterized	YGR126W	n.a.	7	745840	746532	W	Hypothetical protein
14106	S000003359	ORF	Uncharacterized	YGR127W	n.a.	7	746803	747741	W	Hypothetical protein
14108	S000003360	ORF	Verified	YGR128C	UTP8	7	750096	747955	C	Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
14110	S000003361	ORF	Verified	YGR129W	SYF2	7	750405	751052	W	Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression
14112	S000003362	ORF	Uncharacterized	YGR130C	n.a.	7	753849	751399	C	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
14114	S000003363	ORF	Uncharacterized	YGR131W	n.a.	7	754731	755255	W	Hypothetical protein
14116	S000003364	ORF	Verified	YGR132C	PHB1	7	756457	755594	C	Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation
14118	S000003365	ORF	Verified	YGR133W	PEX4	7	756901	757452	W	Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis
14120	S000003366	ORF	Verified	YGR134W	CAF130	7	757775	761143	W	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation
14122	S000003367	ORF	Verified	YGR135W	PRE9	7	761397	762173	W	20S proteasome beta-type subunit; the only nonessential 20S subunit
14124	S000003368	ORF	Verified	YGR136W	LSB1	7	762433	763158	W	Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization
14126	S000003369	ORF	Dubious	YGR137W	n.a.	7	762893	763267	W	Hypothetical protein
14128	S000003370	ORF	Verified	YGR138C	TPO2	7	765611	763767	C	Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily
14130	S000003371	ORF	Dubious	YGR139W	n.a.	7	765731	766069	W	Hypothetical protein
14132	S000003372	ORF	Verified	YGR140W	CBF2	7	767434	770304	W	Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo
14134	S000003373	ORF	Verified	YGR141W	VPS62	7	770574	771977	W	Vacuolar protein sorting (VPS) protein required for cytoplasm to vacuole targeting of proteins
14136	S000003374	ORF	Verified	YGR142W	BTN2	7	772459	773691	W	Cytosolic coiled-coil protein that modulates arginine uptake, interacts with Rhb1p, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase, may have a role in intracellular protein trafficking
14139	S000006512	tRNA	n.a.	tA(AGC)G	n.a.	7	774354	774426	W	tRNA-Ala
14141	S000003375	ORF	Verified	YGR143W	SKN1	7	775198	777513	W	Protein involved in sphingolipid biosynthesis; type II membrane protein with similarity to Kre6p
14146	S000006590	tRNA	n.a.	tG(UCC)G	SUF4	7	779621	779692	W	tRNA-Gly
14148	S000003376	ORF	Verified	YGR144W	THI4	7	780404	781384	W	Protein required for thiamine biosynthesis and for mitochondrial genome stability
14150	S000003377	ORF	Uncharacterized	YGR145W	ENP2	7	781772	783895	W	Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p
14152	S000003378	ORF	Uncharacterized	YGR146C	n.a.	7	784863	784228	C	Hypothetical protein
14154	S000028638	ORF	Uncharacterized	YGR146C-A	n.a.	7	785442	785281	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14156	S000003379	ORF	Verified	YGR147C	NAT2	7	786925	786059	C	N alpha-acetyl-transferase, transfers acetyl group from acetyl coenzyme A to the N-terminal methionine residues of proteins
14158	S000003380	ORF	Verified	YGR148C	RPL24B	7	787784	787317	C	Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate
14160	S000003381	ORF	Uncharacterized	YGR149W	n.a.	7	789036	790334	W	Hypothetical protein
14162	S000003382	ORF	Uncharacterized	YGR150C	n.a.	7	793058	790464	C	Hypothetical protein
14165	S000006523	tRNA	n.a.	tA(UGC)G	n.a.	7	794422	794494	W	tRNA-Ala
14167	S000003383	ORF	Dubious	YGR151C	n.a.	7	794995	794660	C	Hypothetical protein
14169	S000003384	ORF	Verified	YGR152C	RSR1	7	795497	794679	C	GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases
14171	S000003385	ORF	Uncharacterized	YGR153W	n.a.	7	796097	796750	W	Hypothetical protein
14173	S000003386	ORF	Uncharacterized	YGR154C	n.a.	7	797873	796803	C	Omega-class glutathione transferase
14175	S000003387	ORF	Verified	YGR155W	CYS4	7	798548	800071	W	Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis
14177	S000003388	ORF	Verified	YGR156W	PTI1	7	800551	801828	W	Pta1p Interacting protein
14179	S000003389	ORF	Verified	YGR157W	CHO2	7	802445	805054	W	First step in the methylation pathway for phosphatidylcholine biosynthesis; Phosphatidyl-ethanolamine N-methyltransferase
14181	S000003390	ORF	Verified	YGR158C	MTR3	7	806026	805274	C	3'5' exoribonuclease, exosome subunit; nucleolar protein involved in export of mRNA and ribosomal subunits; homologous to the E. coli exonuclease RNase PH
14183	S000003392	ORF	Dubious	YGR160W	n.a.	7	807078	807689	W	Hypothetical protein
14185	S000003391	ORF	Verified	YGR159C	NSR1	7	807661	806417	C	Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis
14187	S000003393	ORF	Uncharacterized	YGR161C	RTS3	7	809425	808634	C	Putative component of the protein phosphatase type 2A complex
14189	S000029726	ORF	Uncharacterized	YGR161W-C	n.a.	7	810232	810510	W	ORF, Uncharacterized
14209	S000006756	tRNA	n.a.	tV(AAC)G2	n.a.	7	823487	823560	W	tRNA-Val
14211	S000003394	ORF	Verified	YGR162W	TIF4631	7	824064	826922	W	Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p
14213	S000003395	ORF	Verified	YGR163W	GTR2	7	827557	828582	W	Cytoplasmic GTP binding protein, negative regulator of the Ran/Tc4 GTPase cycle downstream of Gtr1p; homolog of human RagC and RagD proteins; component of the EGO complex, which is involved in the regulation of microautophagy
14215	S000003396	ORF	Dubious	YGR164W	n.a.	7	828630	828965	W	Hypothetical protein
14217	S000006712	tRNA	n.a.	tR(UCU)G2	n.a.	7	828799	828728	C	tRNA-Arg
14219	S000003397	ORF	Verified	YGR165W	MRPS35	7	829121	830158	W	Mitochondrial ribosomal protein of the small subunit
14221	S000003398	ORF	Verified	YGR166W	KRE11	7	830520	832202	W	Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP (transport protein particle) complex, which is involved in the late steps of endoplasmic reticulum to Golgi transport
14223	S000003399	ORF	Verified	YGR167W	CLC1	7	832461	833162	W	Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function, two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component
14225	S000003400	ORF	Uncharacterized	YGR168C	n.a.	7	834487	833357	C	Hypothetical protein
14227	S000003401	ORF	Verified	YGR169C	PUS6	7	835908	834694	C	Pseudouridine synthase responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability
14229	S000028521	ORF	Uncharacterized	YGR169C-A	n.a.	7	836670	836392	C	Identified by homology to <i>Ashbya gossypii</i>
14231	S000003402	ORF	Verified	YGR170W	PSD2	7	837147	840563	W	Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes, converts phosphatidylserine to phosphatidylethanolamine
14233	S000003403	ORF	Verified	YGR171C	MSM1	7	842556	840829	C	Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p
14235	S000003404	ORF	Verified	YGR172C	YIP1	7	843596	842850	C	Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles
14237	S000003405	ORF	Uncharacterized	YGR173W	RBG2	7	843859	844965	W	Protein with similarity to mammalian developmentally regulated GTP-binding protein
14240	S000006581	tRNA	n.a.	tG(GCC)G1	n.a.	7	845654	845724	W	tRNA-Gly
14242	S000003406	ORF	Verified	YGR174C	CBP4	7	846410	845898	C	Essential for the expression and activity of ubiquinol-cytochrome c reductase; ubiquinol--cytochrome-c reductase assembly factor
14244	S000028639	ORF	Uncharacterized	YGR174W-A	n.a.	7	846660	846746	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14246	S000003407	ORF	Verified	YGR175C	ERG1	7	848428	846938	C	Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine
14248	S000003408	ORF	Dubious	YGR176W	n.a.	7	848725	849072	W	Hypothetical protein
14250	S000003409	ORF	Verified	YGR177C	ATF2	7	850441	848834	C	Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important in brewing
14252	S000003410	ORF	Verified	YGR178C	PBP1	7	853220	851052	C	Protein interacting with poly(A)-binding protein Pab1p; likely involved in control of the extent of mRNA polyadenylation
14254	S000003411	ORF	Verified	YGR179C	OKP1	7	854900	853680	C	Outer kinetochore protein, required for accurate mitotic chromosome segregation; forms a complex with Mcm21p and Okp1p that binds to centromeres via the CBF3 complex
14256	S000003412	ORF	Verified	YGR180C	RNR4	7	856306	855269	C	Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
14258	S000006641	tRNA	n.a.	tL(CAA)G3	n.a.	7	857496	857383	C	tRNA-Leu
14259	S000034251	intron	n.a.	n.a.	n.a.	7	857458	857427	C	n.a.
14262	S000003413	ORF	Verified	YGR181W	TIM13	7	858292	858609	W	Translocase of the inner membrane; mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; Subunit of mitochondrial protein import machinery
14264	S000003414	ORF	Dubious	YGR182C	n.a.	7	858909	858556	C	Hypothetical protein
14266	S000003415	ORF	Verified	YGR183C	QCR9	7	859481	859068	C	Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex
14269	S000032945	intron	n.a.	n.a.	n.a.	7	859478	859266	C	n.a.
14270	S000003416	ORF	Verified	YGR184C	UBR1	7	865758	859906	C	Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome
14272	S000003417	ORF	Verified	YGR185C	TYS1	7	867525	866341	C	Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr
14274	S000003418	ORF	Verified	YGR186W	TFG1	7	867779	869986	W	Largest subunit of the RNA Polymerase general transcription factor IIF (TFIIF), interacts with Fcp1p phosphatase and with TFIIB; potentially phosphorylated by Cdc28p
14276	S000003419	ORF	Verified	YGR187C	HGH1	7	871421	870237	C	Protein of unknown function with similarity to human HMG1 and HMG2; localizes to the cytoplasm
14278	S000003420	ORF	Verified	YGR188C	BUB1	7	875114	872049	C	Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p
14281	S000006623	tRNA	n.a.	tK(CUU)G3	n.a.	7	876399	876471	W	tRNA-Lys
14283	S000003421	ORF	Verified	YGR189C	CRH1	7	878197	876674	C	Putative glycosidase of the cell wall, may have a role in cell wall architecture
14285	S000006772	tRNA	n.a.	tW(CCA)G2	n.a.	7	878820	878715	C	tRNA-Trp
14286	S000032530	intron	n.a.	n.a.	n.a.	7	878784	878751	C	n.a.
14289	S000003423	ORF	Verified	YGR191W	HIP1	7	880425	882236	W	High-affinity histidine permease, also involved in the transport of manganese ions
14291	S000003422	ORF	Dubious	YGR190C	n.a.	7	880666	880301	C	Protein required for cell viability
14293	S000003424	ORF	Verified	YGR192C	TDH3	7	883815	882817	C	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall
14295	S000003425	ORF	Verified	YGR193C	PDX1	7	885746	884514	C	Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core
14297	S000003426	ORF	Verified	YGR194C	XKS1	7	887880	886078	C	Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains
14299	S000003427	ORF	Verified	YGR195W	SKI6	7	888887	889627	W	3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs
14301	S000003428	ORF	Verified	YGR196C	FYV8	7	892191	889738	C	Protein of unknown function, required for survival upon exposure to K1 killer toxin
14303	S000003429	ORF	Verified	YGR197C	SNG1	7	894145	892502	C	Protein involved in nitrosoguanidine (MNNG) resistance; expression is regulated by transcription factors involved in multidrug resistance
14305	S000003430	ORF	Uncharacterized	YGR198W	n.a.	7	894698	897151	W	Essential protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
14307	S000003431	ORF	Verified	YGR199W	PMT6	7	897507	899786	W	Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases
14309	S000003432	ORF	Verified	YGR200C	ELP2	7	902275	899909	C	Elongator protein, part of the six-subunit RNA polymerase II Elongator histone acetyltransferase complex; target of Kluyveromyces lactis zymocin
14311	S000003433	ORF	Uncharacterized	YGR201C	n.a.	7	903202	902525	C	Hypothetical protein
14313	S000003434	ORF	Verified	YGR202C	PCT1	7	904753	903479	C	Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding
14315	S000003435	ORF	Uncharacterized	YGR203W	n.a.	7	905242	905688	W	Probable protein tyrosine phosphatase of the CDC25-like phosphatase family, which includes Mih1p; potential ortholog S. pombe Ibp1 may regulate DNA replication
14317	S000003436	ORF	Verified	YGR204W	ADE3	7	905939	908779	W	Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine
14319	S000028640	ORF	Uncharacterized	YGR204C-A	n.a.	7	909179	909066	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14321	S000003437	ORF	Verified	YGR205W	n.a.	7	909218	910090	W	Protein that binds ATP; crystal structure resembles that of E.coli pantothenate kinase
14323	S000003438	ORF	Uncharacterized	YGR206W	n.a.	7	910437	910742	W	Hypothetical protein
14325	S000003439	ORF	Uncharacterized	YGR207C	n.a.	7	911633	910848	C	Hypothetical protein
14327	S000003440	ORF	Verified	YGR208W	SER2	7	911888	912817	W	Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source
14329	S000003441	ORF	Verified	YGR209C	TRX2	7	913232	912918	C	Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against both oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance
14331	S000003442	ORF	Uncharacterized	YGR210C	n.a.	7	914743	913508	C	Hypothetical protein
14333	S000003443	ORF	Verified	YGR211W	ZPR1	7	915246	916706	W	Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p)
14335	S000003444	ORF	Uncharacterized	YGR212W	SLI1	7	917045	918451	W	N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin
14337	S000003445	ORF	Verified	YGR213C	RTA1	7	919470	918517	C	Protein involved in 7-aminocholesterol resistance; has seven potential membrane-spanning regions
14339	S000003446	ORF	Verified	YGR214W	RPS0A	7	920580	921793	W	Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal
14342	S000035104	intron	n.a.	n.a.	n.a.	7	920670	921124	W	n.a.
14343	S000003447	ORF	Verified	YGR215W	RSM27	7	922180	922512	W	Mitochondrial ribosomal protein of the small subunit
14345	S000003448	ORF	Verified	YGR216C	GPI1	7	924467	922638	C	Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs
14347	S000003449	ORF	Verified	YGR217W	CCH1	7	924699	930818	W	Voltage-gated calcium channel involved in calcium influx in response to mating pheromones
14349	S000006582	tRNA	n.a.	tG(GCC)G2	n.a.	7	931026	930956	C	tRNA-Gly
14353	S000003450	ORF	Verified	YGR218W	CRM1	7	932544	935798	W	Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus
14355	S000003451	ORF	Dubious	YGR219W	n.a.	7	936038	936379	W	Hypothetical protein
14357	S000003452	ORF	Verified	YGR220C	MRPL9	7	936886	936077	C	Mitochondrial ribosomal protein of the large subunit
14359	S000003453	ORF	Verified	YGR221C	TOS2	7	938995	937127	C	Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p
14361	S000006495	snRNA	n.a.	snR7-L	SNR7-L	7	939675	939462	C	U5 spliceosomal RNA; homology to snRNA U5, associated with spliceosome
14363	S000006496	snRNA	n.a.	snR7-S	SNR7-S	7	939675	939497	C	U5 spliceosomal RNA; homology to snRNA U5, associated with spliceosome
14365	S000003454	ORF	Verified	YGR222W	PET54	7	939926	940807	W	Protein required for splicing of the COX1 intron AI5 beta; also specifically required, together with Pet122p and Pet494p, for translation of the COX3 mRNA; located in the mitochondrial inner membrane
14367	S000003455	ORF	Verified	YGR223C	HSV2	7	942218	940872	C	Phosphatidylinositol 3,5-bisphosphate-binding protein, predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization
14369	S000003456	ORF	Verified	YGR224W	AZR1	7	942809	944650	W	Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole
14371	S000003457	ORF	Verified	YGR225W	AMA1	7	945148	946929	W	Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis
14374	S000037308	intron	n.a.	n.a.	n.a.	7	946331	946423	W	n.a.
14375	S000003458	ORF	Uncharacterized	YGR226C	n.a.	7	947003	946404	C	ORF, Uncharacterized
14377	S000003459	ORF	Verified	YGR227W	DIE2	7	947422	948999	W	Dolichyl-phosphoglucose-dependent glucosyltransferase of the ER, functions in the dolichol pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1
14379	S000003460	ORF	Dubious	YGR228W	n.a.	7	949367	949711	W	Hypothetical protein
14381	S000003461	ORF	Verified	YGR229C	SMI1	7	950901	949384	C	Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity
14383	S000003462	ORF	Verified	YGR230W	BNS1	7	951896	952309	W	Protein with some similarity to Spo12p; overexpression bypasses need for Spo12p, but not required for meiosis
14385	S000003463	ORF	Verified	YGR231C	PHB2	7	953482	952550	C	Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation
14387	S000003464	ORF	Verified	YGR232W	NAS6	7	953962	954648	W	Regulatory, non-ATPase subunit of the 26S proteasome; homolog of the human oncoprotein gankyrin, which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4/6
14389	S000003465	ORF	Verified	YGR233C	PHO81	7	958212	954676	C	Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; required for derepression of PHO5; transcriptionally regulated by Pho4p and Pho2p
14391	S000003466	ORF	Verified	YGR234W	YHB1	7	959907	961106	W	Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses
14393	S000003467	ORF	Uncharacterized	YGR235C	n.a.	7	962064	961363	C	Hypothetical protein
14395	S000003468	ORF	Verified	YGR236C	SPG1	7	962821	962432	C	Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources
14397	S000003469	ORF	Uncharacterized	YGR237C	n.a.	7	965660	963303	C	Hypothetical protein
14399	S000003470	ORF	Verified	YGR238C	KEL2	7	968692	966044	C	Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
14401	S000003471	ORF	Verified	YGR239C	PEX21	7	970058	969192	C	Part of a two-member peroxin family (Pex18p and Pex21p) specifically required for peroxisomal targeting of the Pex7p peroxisomal signal recognition factor and PTS2-type peroxisomal matrix proteins
14403	S000003472	ORF	Verified	YGR240C	PFK1	7	973739	970776	C	Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
14405	S000028551	ORF	Uncharacterized	YGR240C-A	n.a.	7	974782	974582	C	Identified by fungal homology and RT-PCR
14407	S000003474	ORF	Dubious	YGR242W	n.a.	7	976420	976728	W	Hypothetical protein
14409	S000003473	ORF	Verified	YGR241C	YAP1802	7	976586	974880	C	Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family
14411	S000003475	ORF	Uncharacterized	YGR243W	n.a.	7	977341	977781	W	The authentic, non-tagged protein was localized to mitochondria
14413	S000003476	ORF	Verified	YGR244C	LSC2	7	979324	978041	C	Beta subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate
14415	S000003477	ORF	Verified	YGR245C	SDA1	7	982073	979770	C	Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis
14417	S000003478	ORF	Verified	YGR246C	BRF1	7	984277	982487	C	TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB
14419	S000003479	ORF	Verified	YGR247W	CPD1	7	984971	985690	W	Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; no detectable phenotype is conferred by null mutation or by overexpression
14421	S000003480	ORF	Verified	YGR248W	SOL4	7	985977	986744	W	6-phosphogluconolactonase with similarity to Sol3p
14423	S000003481	ORF	Verified	YGR249W	MGA1	7	988054	989424	W	Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants
14425	S000003482	ORF	Uncharacterized	YGR250C	n.a.	7	993526	991181	C	Hypothetical protein
14427	S000003483	ORF	Uncharacterized	YGR251W	n.a.	7	995644	996234	W	Protein required for cell viability
14429	S000003484	ORF	Verified	YGR252W	GCN5	7	996874	998193	W	Histone acetyltransferase, acetylates lysine 14 on histone H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily
14431	S000003485	ORF	Verified	YGR253C	PUP2	7	999145	998363	C	Alpha subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta
14433	S000003486	ORF	Verified	YGR254W	ENO1	7	1000932	1002245	W	Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose
14435	S000003487	ORF	Verified	YGR255C	COQ6	7	1003967	1002528	C	Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; located on the matrix side of the mitochondrial inner membrane
14437	S000006750	tRNA	n.a.	tT(UGU)G2	n.a.	7	1004222	1004293	W	tRNA-Thr
14439	S000003488	ORF	Verified	YGR256W	GND2	7	1004630	1006108	W	6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone
14441	S000003489	ORF	Verified	YGR257C	MTM1	7	1007311	1006211	C	Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor
14443	S000003490	ORF	Verified	YGR258C	RAD2	7	1010772	1007677	C	Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein
14445	S000003492	ORF	Verified	YGR260W	TNA1	7	1012491	1014095	W	High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)
14447	S000003491	ORF	Dubious	YGR259C	n.a.	7	1012927	1012487	C	Hypothetical protein
14449	S000003493	ORF	Verified	YGR261C	APL6	7	1016756	1014327	C	Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools
14451	S000003494	ORF	Verified	YGR262C	BUD32	7	1017765	1016980	C	Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
14453	S000003495	ORF	Uncharacterized	YGR263C	n.a.	7	1019247	1017973	C	presents weak similarity to a putative <i>E. coli</i> protein defined as a lipase-like enzyme
14455	S000003497	ORF	Dubious	YGR265W	n.a.	7	1021654	1022064	W	Protein required for cell viability
14457	S000003496	ORF	Verified	YGR264C	MES1	7	1021859	1019604	C	Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs
14459	S000003498	ORF	Uncharacterized	YGR266W	n.a.	7	1022662	1024767	W	probably contains a single transmembrane span
14461	S000003499	ORF	Verified	YGR267C	FOL2	7	1025741	1025010	C	GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway
14463	S000003501	ORF	Dubious	YGR269W	n.a.	7	1026642	1026968	W	Hypothetical protein
14465	S000003500	ORF	Uncharacterized	YGR268C	HUA1	7	1026659	1026063	C	Cytoplasmic protein containing a zinc finger domain with sequence similarity to that of Type I J-proteins; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly
14467	S000003502	ORF	Verified	YGR270W	YTA7	7	1027376	1031515	W	Protein of unknown function, member of CDC48/PAS1/SEC18 family of ATPases, potentially phosphorylated by Cdc28p
14469	S000028641	ORF	Dubious	YGR270C-A	n.a.	7	1027606	1027388	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14471	S000003503	ORF	Verified	YGR271W	SLH1	7	1031797	1037700	W	Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses
14473	S000007608	ORF	Uncharacterized	YGR271C-A	n.a.	7	1037997	1037806	C	Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36.
14475	S000003504	ORF	Uncharacterized	YGR272C	n.a.	7	1038506	1038048	C	Hypothetical protein
14477	S000003505	ORF	Uncharacterized	YGR273C	n.a.	7	1039244	1038720	C	Hypothetical protein
14479	S000003506	ORF	Verified	YGR274C	TAF1	7	1043101	1039901	C	TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression
14481	S000003507	ORF	Verified	YGR275W	RTT102	7	1043282	1043755	W	Regulator of Ty1 Transposition; regulator of Ty1 transposition
14483	S000003508	ORF	Verified	YGR276C	RNH70	7	1045486	1043825	C	3' exoribonuclease, required for 5S and tRNA-Arg3 maturation
14485	S000003509	ORF	Uncharacterized	YGR277C	n.a.	7	1046567	1045650	C	Homolog to human PPAT
14487	S000003510	ORF	Verified	YGR278W	CWC22	7	1046737	1048470	W	Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putative spliceosomal component, based on computational analysis of large-scale protein-protein interaction data
14489	S000003511	ORF	Verified	YGR279C	SCW4	7	1049964	1048804	C	Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating
14491	S000003512	ORF	Verified	YGR280C	PXR1	7	1051731	1050916	C	Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain
14493	S000003513	ORF	Verified	YGR281W	YOR1	7	1052830	1057263	W	Plasma membrane transporter of the ATP-binding cassette (ABC) family, mediates export of many different organic anions including oligomycin
14495	S000003514	ORF	Verified	YGR282C	BGL2	7	1058730	1057789	C	Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance
14497	S000003515	ORF	Uncharacterized	YGR283C	n.a.	7	1060046	1059021	C	Hypothetical protein
14499	S000003516	ORF	Verified	YGR284C	ERV29	7	1061596	1060664	C	Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo
14501	S000003517	ORF	Verified	YGR285C	ZUO1	7	1063159	1061858	C	Cytosolic ribosome-associated chaperone, contains a DnaJ domain; together with Ssz1p, acts as a chaperone for nascent polypeptide chains
14503	S000003518	ORF	Verified	YGR286C	BIO2	7	1064946	1063819	C	Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant
14505	S000003519	ORF	Uncharacterized	YGR287C	n.a.	7	1068997	1067228	C	Hypothetical protein
14507	S000003520	ORF	Verified	YGR288W	MAL13	7	1070299	1071720	W	MAL-activator protein, part of complex locus MAL1; nonfunctional in genomic reference strain S288C
14509	S000003522	ORF	Dubious	YGR290W	n.a.	7	1075488	1075931	W	Hypothetical protein
14511	S000003521	ORF	Verified	YGR289C	MAL11	7	1075819	1073969	C	Maltose permease, inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters
14513	S000003523	ORF	Dubious	YGR291C	n.a.	7	1076510	1076289	C	Hypothetical protein
14515	S000003524	ORF	Verified	YGR292W	MAL12	7	1076605	1078359	W	Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus
14517	S000003526	ORF	Uncharacterized	YGR294W	n.a.	7	1080312	1080674	W	Hypothetical protein
14519	S000003525	ORF	Dubious	YGR293C	n.a.	7	1080352	1079891	C	Hypothetical protein
14521	S000003527	ORF	Verified	YGR295C	COS6	7	1082735	1081590	C	Protein of unknown function, member of a family of conserved, often subtelomerically-encoded proteins
14531	S000003528	ORF	Verified	YGR296W	YRF1-3	7	1084870	1090597	W	Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p
14534	S000031884	intron	n.a.	n.a.	n.a.	7	1084889	1085036	W	n.a.
14535	S000028642	ORF	Dubious	YGR296C-A	n.a.	7	1089451	1088876	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14537	S000028643	ORF	Dubious	YGR296C-B	n.a.	7	1090234	1089752	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14541	S000028644	ORF	Dubious	YHL050W-A	n.a.	8	811	1293	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14543	S000001042	ORF	Uncharacterized	YHL050C	n.a.	8	3310	445	C	Protein of unknown function, potential Cdc28p substrate
14546	S000030584	intron	n.a.	n.a.	n.a.	8	2669	1898	C	n.a.
14547	S000001041	ORF	Uncharacterized	YHL049C	n.a.	8	4540	3725	C	Hypothetical protein
14556	S000028829	ORF	Uncharacterized	YHL048C-A	n.a.	8	5796	5662	C	Identified by expression profiling and mass spectrometry
14558	S000001040	ORF	Verified	YHL048W	COS8	8	6400	7545	W	Nuclear membrane protein, member of a family of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response
14561	S000028775	ORF	Dubious	YHL046W-A	n.a.	8	9979	10305	W	Questionable ORF from MIPS
14563	S000001039	ORF	Verified	YHL047C	ARN2	8	10211	8298	C	Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to the siderophore triacetylfusarinine C
14565	S000001038	ORF	Uncharacterized	YHL046C	n.a.	8	12283	11921	C	Hypothetical protein
14567	S000001037	ORF	Dubious	YHL045W	n.a.	8	12500	12847	W	Hypothetical protein
14569	S000001036	ORF	Uncharacterized	YHL044W	n.a.	8	13563	14270	W	Putative integral membrane protein, member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern
14571	S000001035	ORF	Verified	YHL043W	ECM34	8	14899	15411	W	Non-essential protein of unknown function
14573	S000001034	ORF	Uncharacterized	YHL042W	n.a.	8	15665	16117	W	Hypothetical protein
14575	S000001033	ORF	Dubious	YHL041W	n.a.	8	17390	17839	W	Hypothetical protein
14577	S000001032	ORF	Verified	YHL040C	ARN1	8	20968	19085	C	Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores
14579	S000001031	ORF	Uncharacterized	YHL039W	n.a.	8	21780	23537	W	Hypothetical protein
14581	S000001030	ORF	Verified	YHL038C	CBP2	8	25506	23614	C	Protein required for splicing of COB aI5 intron; Cytochrome B pre-mRNA processing protein
14583	S000001029	ORF	Dubious	YHL037C	n.a.	8	26177	25698	C	Hypothetical protein
14585	S000001028	ORF	Verified	YHL036W	MUP3	8	26239	27879	W	Low affinity methionine permease, similar to Mup1p
14587	S000001027	ORF	Uncharacterized	YHL035C	n.a.	8	32754	27976	C	Protein of unknown function, member of the ATP-binding cassette (ABC) family, potential Cdc28p substrate
14589	S000028774	ORF	Dubious	YHL034W-A	n.a.	8	33174	33635	W	Hypothetical protein
14591	S000001026	ORF	Verified	YHL034C	SBP1	8	34075	33191	C	Nucleolar single-strand nucleic acid binding protein; associates with small nuclear RNAs
14593	S000001025	ORF	Verified	YHL033C	RPL8A	8	36023	35253	C	Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits
14595	S000001024	ORF	Verified	YHL032C	GUT1	8	38506	36377	C	Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p
14597	S000028773	ORF	Dubious	YHL030W-A	n.a.	8	39072	39533	W	Questionable ORF from MIPS
14599	S000001023	ORF	Verified	YHL031C	GOS1	8	39484	38813	C	v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28
14601	S000001022	ORF	Verified	YHL030W	ECM29	8	40082	45688	W	Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome
14603	S000001021	ORF	Uncharacterized	YHL029C	n.a.	8	47966	45927	C	Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts
14605	S000001020	ORF	Verified	YHL028W	WSC4	8	48761	50578	W	cell wall integrity and stress response component 4; Putative integral membrane protein containing novel cysteine motif. Similarity to SLG1 (WSC1), WSC2 and WSC3
14607	S000001019	ORF	Verified	YHL027W	RIM101	8	51109	52986	W	Transcriptional repressor involved in the response to pH; required for alkaline pH-stimulated differentiation pathways such as haploid invasive growth and sporulation; activated by proteolytic processing; has similarity to the A. nidulans transcription factor PacC
14609	S000001018	ORF	Uncharacterized	YHL026C	n.a.	8	54023	53217	C	Hypothetical protein
14611	S000001017	ORF	Verified	YHL025W	SNF6	8	54848	55846	W	One of 11 subunits of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p
14613	S000001016	ORF	Verified	YHL024W	RIM4	8	56646	58787	W	Putative RNA-binding protein required for the expression of early and middle sporulation genes
14615	S000001015	ORF	Verified	YHL023C	RMD11	8	62560	59120	C	Protein required for sporulation
14617	S000006597	tRNA	n.a.	tH(GUG)H	n.a.	8	62752	62823	W	tRNA-His
14619	S000001014	ORF	Verified	YHL022C	SPO11	8	64154	62958	C	Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation
14621	S000001013	ORF	Uncharacterized	YHL021C	n.a.	8	65855	64458	C	The authentic, non-tagged protein was localized to the mitochondria
14623	S000001012	ORF	Verified	YHL020C	OPI1	8	67452	66238	C	Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes
14625	S000028772	ORF	Dubious	YHL019W-A	n.a.	8	67707	68300	W	Questionable ORF from MIPS
14627	S000001011	ORF	Verified	YHL019C	APM2	8	69544	67727	C	Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport
14629	S000001010	ORF	Uncharacterized	YHL018W	n.a.	8	69704	70066	W	Hypothetical protein
14631	S000001009	ORF	Uncharacterized	YHL017W	n.a.	8	70272	71870	W	Hypothetical protein
14633	S000001008	ORF	Verified	YHL016C	DUR3	8	74240	72033	C	Plasma membrane urea transporter, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway
14635	S000028828	ORF	Uncharacterized	YHL015W-A	n.a.	8	74695	74778	W	Identified by expression profiling and mass spectrometry
14637	S000001007	ORF	Verified	YHL015W	RPS20	8	75408	75773	W	Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins
14639	S000001006	ORF	Verified	YHL014C	YLF2	8	77310	76093	C	Protein with weak similarity to B. subtilis GTP-binding protein and to human glycogen phosphorylases
14641	S000001005	ORF	Uncharacterized	YHL013C	n.a.	8	78349	77426	C	Hypothetical protein
14643	S000001004	ORF	Uncharacterized	YHL012W	n.a.	8	78931	80412	W	Hypothetical protein
14645	S000001003	ORF	Verified	YHL011C	PRS3	8	81611	80649	C	5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, involved in nucleotide, histidine, and tryptophan biosynthesis; one of a five related enzymes, which are active as heteromultimeric complexes
14647	S000001002	ORF	Uncharacterized	YHL010C	n.a.	8	83716	81959	C	Hypothetical protein
14649	S000001001	ORF	Verified	YHL009C	YAP3	8	85055	84063	C	Basic leucine zipper (bZIP) transcription factor
14651	S000006758	tRNA	n.a.	tV(AAC)H	n.a.	8	85366	85293	C	tRNA-Val
14665	S000001000	ORF	Uncharacterized	YHL008C	n.a.	8	94505	92622	C	Hypothetical protein
14667	S000028771	ORF	Dubious	YHL006W-A	n.a.	8	97727	98080	W	Questionable ORF from MIPS
14669	S000000999	ORF	Verified	YHL007C	STE20	8	97932	95113	C	Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal/invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases
14671	S000000998	ORF	Uncharacterized	YHL006C	SHU1	8	98790	98338	C	Protein of unassigned function involved in mutation suppression, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu2p, Psy3p, and Csm2p
14673	S000000996	ORF	Verified	YHL004W	MRP4	8	99214	100398	W	Mitochondrial ribosomal protein of the small subunit
14675	S000000997	ORF	Dubious	YHL005C	n.a.	8	99215	98823	C	Hypothetical protein
14677	S000000995	ORF	Verified	YHL003C	LAG1	8	101878	100643	C	Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p
14679	S000000994	ORF	Verified	YHL002W	HSE1	8	102606	103964	W	Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes
14681	S000028770	ORF	Dubious	YHL002C-A	n.a.	8	103069	102581	C	Questionable ORF from MIPS
14683	S000000993	ORF	Verified	YHL001W	RPL14B	8	104271	105085	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Ap and has similarity to rat L14 ribosomal protein
14686	S000036894	intron	n.a.	n.a.	n.a.	8	104400	104797	W	n.a.
14691	S000001043	ORF	Verified	YHR001W	OSH7	8	106049	107362	W	Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability
14693	S000003529	ORF	Verified	YHR001W-A	QCR10	8	107820	108116	W	8.5 kDa subunit of the ubiqunol-cytochrome c oxidoreductase complex
14696	S000035664	intron	n.a.	n.a.	n.a.	8	107826	107888	W	n.a.
14697	S000001044	ORF	Verified	YHR002W	LEU5	8	108806	109879	W	Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized
14699	S000001045	ORF	Uncharacterized	YHR003C	n.a.	8	111311	110022	C	Hypothetical protein
14701	S000001046	ORF	Verified	YHR004C	NEM1	8	113088	111748	C	Protein of the nuclear envelope required for the spherical shape of the nucleus; required for normal sporulation
14703	S000001047	ORF	Verified	YHR005C	GPA1	8	114911	113493	C	GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates the pathway via Scp160p
14705	S000003530	ORF	Verified	YHR005C-A	MRS11	8	115895	115614	C	Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane, has homology to Mrs5p, which is also involved in this process
14707	S000006740	tRNA	n.a.	tT(AGU)H	n.a.	8	116173	116101	C	tRNA-Thr
14711	S000001048	ORF	Verified	YHR006W	STP2	8	117808	119433	W	Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes
14713	S000001049	ORF	Verified	YHR007C	ERG11	8	121677	120085	C	Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family
14715	S000028830	ORF	Uncharacterized	YHR007C-A	n.a.	8	122759	122544	C	Identified by expression profiling and mass spectrometry
14717	S000001050	ORF	Verified	YHR008C	SOD2	8	123584	122883	C	Manganese-containing superoxide dismutase
14719	S000001051	ORF	Uncharacterized	YHR009C	n.a.	8	125674	124103	C	Hypothetical protein
14721	S000001052	ORF	Verified	YHR010W	RPL27A	8	126514	127485	W	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein
14724	S000036520	intron	n.a.	n.a.	n.a.	8	126545	127105	W	n.a.
14725	S000001053	ORF	Verified	YHR011W	DIA4	8	127773	129113	W	Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth
14727	S000001054	ORF	Verified	YHR012W	VPS29	8	129474	130441	W	Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval
14730	S000036740	intron	n.a.	n.a.	n.a.	8	129522	129640	W	n.a.
14731	S000001055	ORF	Verified	YHR013C	ARD1	8	131439	130723	C	Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing
14733	S000001056	ORF	Verified	YHR014W	SPO13	8	132039	132914	W	Meiosis-specific protein of unknown function, involved in maintaining sister chromatid cohesion during meiosis I as well as promoting proper attachment of kinetochores to the spindle during meiosis I and meiosis II
14735	S000006726	tRNA	n.a.	tS(AGA)H	n.a.	8	133099	133018	C	tRNA-Ser
14740	S000006698	tRNA	n.a.	tQ(UUG)H	n.a.	8	134313	134384	W	tRNA-Gln
14742	S000001057	ORF	Verified	YHR015W	MIP6	8	134546	136525	W	Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export
14744	S000001058	ORF	Verified	YHR016C	YSC84	8	138447	136873	C	Protein involved in the organization of the actin cytoskeleton; contains SH3 domain similar to Rvs167p
14747	S000030437	intron	n.a.	n.a.	n.a.	8	138400	138233	C	n.a.
14748	S000001059	ORF	Verified	YHR017W	YSC83	8	138686	139843	W	similar to S. douglasii YSD83
14750	S000001060	ORF	Verified	YHR018C	ARG4	8	141394	140003	C	Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway
14752	S000001061	ORF	Verified	YHR019C	DED81	8	143550	141886	C	Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA
14754	S000001062	ORF	Uncharacterized	YHR020W	n.a.	8	143988	146054	W	Protein required for cell viability
14756	S000006513	tRNA	n.a.	tA(AGC)H	n.a.	8	146306	146234	C	tRNA-Ala
14760	S000001063	ORF	Verified	YHR021C	RPS27B	8	148661	147863	C	Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein
14763	S000031621	intron	n.a.	n.a.	n.a.	8	148658	148109	C	n.a.
14764	S000003531	ORF	Uncharacterized	YHR021W-A	ECM12	8	149217	149672	W	Non-essential protein of unknown function
14766	S000001064	ORF	Uncharacterized	YHR022C	n.a.	8	150337	149567	C	Hypothetical protein
14768	S000028645	ORF	Uncharacterized	YHR022C-A	n.a.	8	151298	151209	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14770	S000001065	ORF	Verified	YHR023W	MYO1	8	151658	157444	W	Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively
14772	S000001066	ORF	Verified	YHR024C	MAS2	8	159184	157736	C	Larger subunit of the mitochondrial processing protease, essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins
14774	S000001067	ORF	Verified	YHR025W	THR1	8	159430	160503	W	Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway
14776	S000001068	ORF	Verified	YHR026W	PPA1	8	160836	161477	W	Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain
14778	S000001069	ORF	Verified	YHR027C	RPN1	8	164703	161722	C	Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein?protein interactions
14780	S000028776	ORF	Dubious	YHR028W-A	n.a.	8	167344	167664	W	Questionable ORF from MIPS
14782	S000001070	ORF	Verified	YHR028C	DAP2	8	167426	164970	C	Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p
14784	S000001071	ORF	Uncharacterized	YHR029C	n.a.	8	168553	167669	C	Hypothetical protein
14786	S000001072	ORF	Verified	YHR030C	SLT2	8	170336	168882	C	Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway
14788	S000001073	ORF	Verified	YHR031C	RRM3	8	172962	170791	C	DNA helicase involved in rDNA replication and Ty1 transposition; structurally and functionally related to Pif1p
14790	S000001074	ORF	Uncharacterized	YHR032W	n.a.	8	173336	175081	W	Hypothetical protein
14792	S000028831	ORF	Dubious	YHR032W-A	n.a.	8	175187	175366	W	Identified by expression profiling and mass spectrometry
14794	S000028646	ORF	Dubious	YHR032C-A	n.a.	8	175386	175267	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14796	S000001075	ORF	Uncharacterized	YHR033W	n.a.	8	175540	176811	W	Hypothetical protein
14798	S000001076	ORF	Verified	YHR034C	PIH1	8	177991	176957	C	Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)
14800	S000001077	ORF	Uncharacterized	YHR035W	n.a.	8	178211	180103	W	Hypothetical protein
14802	S000001078	ORF	Uncharacterized	YHR036W	n.a.	8	180337	181752	W	Protein required for cell viability
14804	S000001079	ORF	Verified	YHR037W	PUT2	8	181969	183696	W	Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism
14806	S000001080	ORF	Verified	YHR038W	RRF1	8	184058	184750	W	Mitochondrial ribosome recycling factor, essential for mitochondrial protein synthesis and for the maintenance of the respiratory function of mitochondria
14808	S000001081	ORF	Verified	YHR039C	MSC7	8	186801	184867	C	Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids
14810	S000002100	ORF	Verified	YHR039C-A	VMA10	8	187671	187165	C	Vacuolar H+ ATPase subunit G of the catalytic (V1) sector
14813	S000035241	intron	n.a.	n.a.	n.a.	8	187668	187507	C	n.a.
14814	S000001082	ORF	Verified	YHR040W	BCD1	8	187916	189016	W	Essential protein required for the accumulation of box C/D snoRNA
14816	S000001083	ORF	Verified	YHR041C	SRB2	8	189856	189123	C	RNA polymerase II holoenzyme/mediator subunit
14819	S000032052	intron	n.a.	n.a.	n.a.	8	189842	189742	C	n.a.
14820	S000001084	ORF	Verified	YHR042W	NCP1	8	190535	192610	W	NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p
14822	S000001085	ORF	Verified	YHR043C	DOG2	8	193537	192797	C	2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed
14824	S000001086	ORF	Verified	YHR044C	DOG1	8	194800	194060	C	2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight phosphatases; confers 2-deoxyglucose resistance when overexpressed, in vivo substrate has not yet been identified
14826	S000001087	ORF	Uncharacterized	YHR045W	n.a.	8	195543	197225	W	Hypothetical protein
14828	S000001088	ORF	Verified	YHR046C	INM1	8	198277	197390	C	Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate
14830	S000001089	ORF	Verified	YHR047C	AAP1'	8	201302	198732	C	Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation
14832	S000001090	ORF	Uncharacterized	YHR048W	n.a.	8	204599	206143	W	Hypothetical protein
14834	S000001091	ORF	Verified	YHR049W	FSH1	8	206454	207185	W	Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh2p and Fsh3p
14836	S000003532	ORF	Dubious	YHR049C-A	n.a.	8	207523	207212	C	Hypothetical protein
14838	S000001092	ORF	Verified	YHR050W	SMF2	8	207647	209296	W	Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins
14840	S000028832	ORF	Uncharacterized	YHR050W-A	n.a.	8	209468	209638	W	Identified by expression profiling and mass spectrometry
14842	S000001093	ORF	Verified	YHR051W	COX6	8	209698	210144	W	Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels
14844	S000001094	ORF	Verified	YHR052W	CIC1	8	210841	211971	W	Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles
14846	S000028470	ncRNA	n.a.	RUF5-1	RUF5-1	8	212410	213119	W	RNA of Unknown Function
14848	S000028647	ORF	Dubious	YHR052W-A	n.a.	8	212511	212705	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14850	S000001095	ORF	Verified	YHR053C	CUP1-1	8	212721	212536	C	Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
14852	S000001096	ORF	Uncharacterized	YHR054C	n.a.	8	214250	213186	C	Hypothetical protein
14854	S000028474	ncRNA	n.a.	RUF5-2	RUF5-2	8	214408	215117	W	RNA of Unknown Function
14856	S000028648	ORF	Dubious	YHR054W-A	n.a.	8	214509	214703	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
14858	S000001097	ORF	Verified	YHR055C	CUP1-2	8	214719	214534	C	Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C
14860	S000028777	ORF	Dubious	YHR056W-A	n.a.	8	217407	217841	W	Questionable ORF from MIPS
14862	S000001098	ORF	Verified	YHR056C	RSC30	8	217835	215184	C	One of 15 subunits of the 'Remodel the Structure of Chromatin' (RSC) complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc3p; null mutants are osmosensitive
14864	S000001099	ORF	Verified	YHR057C	CPR2	8	218844	218227	C	Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway
14866	S000001100	ORF	Verified	YHR058C	MED6	8	219885	218998	C	RNA polymerase II transcriptional regulation mediator; RNA polymerase II mediator subunit
14868	S000001101	ORF	Verified	YHR059W	FYV4	8	220109	220501	W	Protein of unknown function, required for survival upon exposure to K1 killer toxin
14870	S000001102	ORF	Verified	YHR060W	VMA22	8	220726	221271	W	Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)
14872	S000001103	ORF	Verified	YHR061C	GIC1	8	222479	221535	C	Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain
14874	S000001104	ORF	Verified	YHR062C	RPP1	8	223759	222878	C	Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends
14876	S000001105	ORF	Verified	YHR063C	PAN5	8	225170	224031	C	2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE
14878	S000028778	ORF	Dubious	YHR063W-A	n.a.	8	225443	225778	W	Questionable ORF from MIPS
14880	S000001106	ORF	Verified	YHR064C	SSZ1	8	227142	225526	C	Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that is bound to the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5
14882	S000001107	ORF	Verified	YHR065C	RRP3	8	229038	227533	C	Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity
14884	S000001108	ORF	Verified	YHR066W	SSF1	8	229336	230697	W	Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family
14886	S000001109	ORF	Verified	YHR067W	HTD2	8	230971	231813	W	Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology
14888	S000001110	ORF	Verified	YHR068W	DYS1	8	232134	233297	W	Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric
14890	S000001111	ORF	Verified	YHR069C	RRP4	8	234659	233580	C	Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp43p and Dis3p
14892	S000001112	ORF	Verified	YHR070W	TRM5	8	234882	236381	W	tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya
14894	S000028779	ORF	Dubious	YHR069C-A	n.a.	8	235237	234875	C	Hypothetical protein
14896	S000028780	ORF	Dubious	YHR070C-A	n.a.	8	236513	236103	C	Questionable ORF from MIPS
14898	S000001113	ORF	Verified	YHR071W	PCL5	8	237005	237694	W	Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity
14900	S000006566	tRNA	n.a.	tF(GAA)H1	n.a.	8	237940	237849	C	tRNA-Phe
14901	S000032801	intron	n.a.	n.a.	n.a.	8	237903	237885	C	n.a.
14904	S000001114	ORF	Verified	YHR072W	ERG7	8	239099	241294	W	Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis
14906	S000028781	ORF	Dubious	YHR071C-A	n.a.	8	239231	238911	C	Questionable ORF from MIPS
14908	S000007455	ORF	Verified	YHR072W-A	NOP10	8	241665	241841	W	Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA
14910	S000001115	ORF	Verified	YHR073W	OSH3	8	242583	245573	W	Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability
14912	S000028834	ORF	Dubious	YHR073W-A	n.a.	8	242869	243045	W	Identified by expression profiling and mass spectrometry
14914	S000028833	ORF	Dubious	YHR073C-B	n.a.	8	245503	245423	C	Identified by expression profiling and mass spectrometry
14916	S000001116	ORF	Verified	YHR074W	QNS1	8	246194	248338	W	Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide
14918	S000001117	ORF	Verified	YHR075C	PPE1	8	249642	248440	C	Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein
14920	S000001118	ORF	Verified	YHR076W	PTC7	8	251102	252226	W	Mitochondrially localized type 2C protein phosphatase; expression induced by growth on ethanol and by sustained osmotic stress; possible role in carbon source utilization in low oxygen environments
14922	S000001119	ORF	Verified	YHR077C	NMD2	8	255757	252375	C	Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p
14925	S000037865	intron	n.a.	n.a.	n.a.	8	255751	255639	C	n.a.
14926	S000001120	ORF	Uncharacterized	YHR078W	n.a.	8	256361	258019	W	Hypothetical protein
14928	S000001121	ORF	Verified	YHR079C	IRE1	8	261592	258245	C	Serine-threonine kinase and endoribonuclease; transmembrane protein that initiates the unfolded protein response signal by regulating synthesis of Hac1p through HAC1 mRNA splicing
14930	S000001957	ORF	Verified	YHR079C-A	SAE3	8	262554	262402	C	Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p
14932	S000001122	ORF	Uncharacterized	YHR080C	n.a.	8	266839	262802	C	Hypothetical protein
14934	S000001123	ORF	Verified	YHR081W	LRP1	8	267539	268093	W	Substrate-specific nuclear cofactor for exosome activity in the processing of stable RNAs; homolog of mammalian nuclear matrix protein C1D, which is involved in regulation of DNA repair and recombination
14936	S000001124	ORF	Verified	YHR082C	KSP1	8	271549	268460	C	Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation
14938	S000001125	ORF	Verified	YHR083W	SAM35	8	272628	273617	W	Essential component of the sorting and assembly machinery (SAM complex, aka TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane
14940	S000001126	ORF	Verified	YHR084W	STE12	8	274175	276241	W	Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth
14942	S000001127	ORF	Verified	YHR085W	IPI1	8	276765	277769	W	Protein of unknown function, essential for viability, may be involved in rRNA processing
14944	S000001128	ORF	Verified	YHR086W	NAM8	8	278154	279725	W	RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA
14946	S000028552	ORF	Uncharacterized	YHR086W-A	n.a.	8	280232	280393	W	Identified by fungal homology and RT-PCR
14948	S000001129	ORF	Uncharacterized	YHR087W	n.a.	8	280821	281156	W	Protein involved in RNA metabolism, one of two yeast homologs (with Sdo1p/Ylr022cp) of the human protein SBDS responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome, also conserved in Archaea
14950	S000001130	ORF	Verified	YHR088W	RPF1	8	281496	282383	W	Nucleolar protein involved in the assembly of the large ribosomal subunit; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA
14952	S000001131	ORF	Verified	YHR089C	GAR1	8	283299	282682	C	Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA
14954	S000001132	ORF	Verified	YHR090C	YNG2	8	284626	283778	C	Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1
14956	S000001133	ORF	Verified	YHR091C	MSR1	8	286771	284840	C	Mitochondrial arginyl-tRNA synthetase
14958	S000001134	ORF	Verified	YHR092C	HXT4	8	288813	287131	C	High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose
14960	S000001135	ORF	Dubious	YHR093W	AHT1	8	289144	289692	W	Dubious open reading frame, unlikely to encode a protein; not conserved in closely related Saccharomyces species; multicopy suppressor of glucose transport defects, likely due to the presence of an HXT4 regulatory element in the region
14962	S000001136	ORF	Verified	YHR094C	HXT1	8	292627	290915	C	Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting
14964	S000001137	ORF	Dubious	YHR095W	n.a.	8	292945	293379	W	Hypothetical protein
14966	S000001138	ORF	Verified	YHR096C	HXT5	8	296449	294671	C	Hexose transporter with moderate affinity for glucose, may function in accumulation of reserve carbohydrates during stress, expression induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs
14968	S000001139	ORF	Uncharacterized	YHR097C	n.a.	8	298611	297387	C	Hypothetical protein
14971	S000035268	intron	n.a.	n.a.	n.a.	8	298486	298363	C	n.a.
14972	S000001140	ORF	Verified	YHR098C	SFB3	8	301936	299147	C	Member of the Sec24p family; forms a complex, with Sec23p, that is involved in sorting of Pma1p into COPII vesicles; peripheral ER membrane protein; potential Cdc28p substrate
14974	S000001141	ORF	Verified	YHR099W	TRA1	8	302763	313997	W	Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation
14976	S000001142	ORF	Uncharacterized	YHR100C	n.a.	8	314675	314118	C	Hypothetical protein
14978	S000001143	ORF	Verified	YHR101C	BIG1	8	315970	314876	C	Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan
14981	S000035671	intron	n.a.	n.a.	n.a.	8	315860	315774	C	n.a.
14982	S000001144	ORF	Verified	YHR102W	KIC1	8	316574	319816	W	Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body
14984	S000001145	ORF	Verified	YHR103W	SBE22	8	320416	322974	W	Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth
14986	S000001146	ORF	Verified	YHR104W	GRE3	8	323411	324394	W	Aldose reductase involved in methylglyoxal, d-xylose and arabinose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway
14988	S000001147	ORF	Uncharacterized	YHR105W	YPT35	8	324768	325412	W	Hypothetical protein
14990	S000001148	ORF	Verified	YHR106W	TRR2	8	325600	326628	W	Mitochondrial thioredoxin reductase involved in protection against oxidative stress, required with Glr1p to maintain the redox state of Trx3p, contains active-site motif (CAVC) present in prokaryotic thioredoxin reductases, binds NADPH and FAD
14992	S000001149	ORF	Verified	YHR107C	CDC12	8	328038	326815	C	Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM
14994	S000001150	ORF	Verified	YHR108W	GGA2	8	328305	330062	W	Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi
14996	S000001151	ORF	Verified	YHR109W	CTM1	8	330312	332069	W	Cytochrome c lysine methyltransferase, trimethylates residue 72 of apo-cytochrome c (Cyc1p) in the cytosol; not required for normal respiratory growth
14998	S000001152	ORF	Verified	YHR110W	ERP5	8	332284	332922	W	Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport
15000	S000001153	ORF	Verified	YHR111W	UBA4	8	333074	334396	W	Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response
15002	S000001154	ORF	Uncharacterized	YHR112C	n.a.	8	335665	334529	C	Hypothetical protein
15004	S000001155	ORF	Uncharacterized	YHR113W	n.a.	8	336339	337811	W	Putative metalloprotease
15006	S000001156	ORF	Verified	YHR114W	BZZ1	8	338085	339986	W	SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins
15008	S000001157	ORF	Verified	YHR115C	DMA1	8	341361	340111	C	Protein involved in regulating spindle position and orientation, functionally redundant with Dma2p; homolog of S. pombe Dma1 and H. sapiens Chfr
15010	S000001158	ORF	Verified	YHR116W	COX23	8	341667	342122	W	Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p
15012	S000001159	ORF	Verified	YHR117W	TOM71	8	342351	344270	W	Translocase of the Outer Mitochondrial membrane, 71.9 kDa; 71-kDa component of the protein translocase of the outer membrane of mitochondria
15014	S000001160	ORF	Verified	YHR118C	ORC6	8	345630	344323	C	Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; may be phosphorylated by Cdc28p
15016	S000001161	ORF	Verified	YHR119W	SET1	8	346045	349287	W	Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates Rad6p ubiquitinated histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain
15018	S000001162	ORF	Verified	YHR120W	MSH1	8	349576	352455	W	DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis
15020	S000001163	ORF	Uncharacterized	YHR121W	LSM12	8	352758	353321	W	Protein containing an Lsm domain and an AD domain; may bind RNA and have a role in RNA processing
15022	S000001164	ORF	Uncharacterized	YHR122W	n.a.	8	353627	354322	W	Protein required for cell viability
15024	S000001165	ORF	Verified	YHR123W	EPT1	8	354817	356083	W	sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability
15027	S000036153	intron	n.a.	n.a.	n.a.	8	354867	354957	W	n.a.
15028	S000001166	ORF	Verified	YHR124W	NDT80	8	356563	358446	W	Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE)
15030	S000006567	tRNA	n.a.	tF(GAA)H2	n.a.	8	358571	358480	C	tRNA-Phe
15031	S000032804	intron	n.a.	n.a.	n.a.	8	358534	358516	C	n.a.
15035	S000001167	ORF	Dubious	YHR125W	n.a.	8	358860	359165	W	Hypothetical protein
15039	S000001168	ORF	Uncharacterized	YHR126C	n.a.	8	360183	359704	C	Hypothetical protein
15041	S000001169	ORF	Uncharacterized	YHR127W	n.a.	8	360915	361646	W	(H)igh copy (S)uppressor of (N)34 dominant negative allele of SEC4. Suppression is very specific to this allele. It has no affect on the analogous YPT1 allele. No homology or known function.
15043	S000001170	ORF	Verified	YHR128W	FUR1	8	362117	362767	W	Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway
15045	S000001171	ORF	Verified	YHR129C	ARP1	8	364155	363001	C	Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; putative ortholog of mammalian centractin
15047	S000001172	ORF	Dubious	YHR130C	n.a.	8	365302	364967	C	Hypothetical protein
15049	S000028782	ORF	Dubious	YHR131W-A	n.a.	8	367749	367994	W	Questionable ORF from MIPS
15051	S000001173	ORF	Uncharacterized	YHR131C	n.a.	8	367894	365342	C	Hypothetical protein
15053	S000001174	ORF	Verified	YHR132C	ECM14	8	369796	368504	C	Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly
15055	S000007496	ORF	Uncharacterized	YHR132W-A	n.a.	8	370056	370451	W	Hypothetical protein
15057	S000001175	ORF	Uncharacterized	YHR133C	n.a.	8	371599	370724	C	Protein of unknown function, potential homolog of mammalian Insig 1; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery
15059	S000001176	ORF	Verified	YHR134W	WSS1	8	371751	372560	W	weak suppressor of smt3
15061	S000001177	ORF	Verified	YHR135C	YCK1	8	374312	372696	C	Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p
15063	S000001178	ORF	Verified	YHR136C	SPL2	8	375102	374656	C	Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern
15065	S000001179	ORF	Verified	YHR137W	ARO9	8	375711	377252	W	Aromatic aminotransferase, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism
15067	S000028649	ORF	Dubious	YHR137C-A	n.a.	8	376390	375740	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15069	S000001180	ORF	Uncharacterized	YHR138C	n.a.	8	377701	377357	C	Homologous to PBI2
15071	S000001181	ORF	Verified	YHR139C	SPS100	8	379201	378221	C	Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall
15073	S000003533	ORF	Dubious	YHR139C-A	n.a.	8	380421	380110	C	Hypothetical protein
15075	S000001182	ORF	Uncharacterized	YHR140W	n.a.	8	380574	381293	W	Hypothetical protein
15077	S000007297	snoRNA	n.a.	snR32	SNR32	8	381542	381729	W	H/ACA small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit rRNA at position 2190
15079	S000001183	ORF	Verified	YHR141C	RPL42B	8	382753	381992	C	Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus
15082	S000033512	intron	n.a.	n.a.	n.a.	8	382749	382309	C	n.a.
15083	S000001184	ORF	Verified	YHR142W	CHS7	8	383540	384490	W	Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER
15085	S000001186	ORF	Verified	YHR143W	DSE2	8	385512	386489	W	Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP
15087	S000001185	ORF	Verified	YHR143W-A	RPC10	8	387235	387447	W	RNA polymerase subunit, found in RNA polymerase complexes I, II, and III
15089	S000001187	ORF	Verified	YHR144C	DCD1	8	388728	387790	C	Deaminase required for dCTP and dTTP synthesis; expression is cell cycle regulated
15091	S000006682	tRNA	n.a.	tP(UGG)H	SUF8	8	388997	388895	C	tRNA-Pro
15092	S000035984	intron	n.a.	n.a.	n.a.	8	388961	388931	C	n.a.
15095	S000001188	ORF	Dubious	YHR145C	n.a.	8	389339	388983	C	Hypothetical protein
15099	S000001189	ORF	Verified	YHR146W	CRP1	8	390302	391699	W	Protein that binds to cruciform DNA structures
15101	S000001190	ORF	Verified	YHR147C	MRPL6	8	393285	392641	C	Mitochondrial ribosomal protein of the large subunit
15103	S000001191	ORF	Verified	YHR148W	IMP3	8	393536	394087	W	Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA
15105	S000001192	ORF	Uncharacterized	YHR149C	SKG6	8	396661	394457	C	Protein of unknown function; found in the bud tip and bud neck, potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p
15107	S000001193	ORF	Verified	YHR150W	PEX28	8	397253	398992	W	Peroxisomal integral membrane protein, involved in regulation of peroxisome size and number; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p
15109	S000001194	ORF	Uncharacterized	YHR151C	n.a.	8	400850	399270	C	Hypothetical protein
15111	S000001195	ORF	Verified	YHR152W	SPO12	8	401436	401957	W	Nucleolar protein of unknown function, positive regulator of exit from mitosis; involved in regulating the release of Cdc14p from the nucleolus in early anaphase; proposed to play similar role in meiosis
15113	S000001196	ORF	Verified	YHR153C	SPO16	8	402684	402088	C	Protein of unknown function, required for spore formation
15115	S000001197	ORF	Verified	YHR154W	RTT107	8	402968	406180	W	Protein that interacts with Mms22p and is implicated in Mms22-dependent DNA repair during S phase, damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; has four BRCT domains; has a role in regulation of Ty1 transposition
15117	S000001198	ORF	Uncharacterized	YHR155W	YSP1	8	407105	410791	W	Hypothetical protein
15119	S000006462	snoRNA	n.a.	snR71	SNR71	8	411230	411319	W	guides 2'-O-methylation on large subunit rRNA at A2943; small nucleolar RNA snR71
15121	S000001199	ORF	Verified	YHR156C	LIN1	8	412408	411386	C	Nuclear protein that physically interacts with Irr1p, a component of the cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication
15123	S000001200	ORF	Verified	YHR157W	REC104	8	412909	413457	W	Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination
15125	S000001201	ORF	Verified	YHR158C	KEL1	8	417181	413687	C	Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate
15127	S000001202	ORF	Uncharacterized	YHR159W	n.a.	8	417551	419065	W	Protein of unknown function that localizes to the cytoplasm, potential Cdc28p substrate
15129	S000001203	ORF	Verified	YHR160C	PEX18	8	420074	419223	C	Part of a two-member peroxin family (Pex18p and Pex21p) specifically required for peroxisomal targeting of the Pex7p peroxisomal signal recognition factor and PTS2 peroxisomal matrix proteins
15131	S000001204	ORF	Verified	YHR161C	YAP1801	8	422288	420375	C	Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1802p, member of the AP180 protein family
15133	S000001205	ORF	Uncharacterized	YHR162W	n.a.	8	423074	423463	W	Hypothetical protein
15135	S000001206	ORF	Verified	YHR163W	SOL3	8	423632	424474	W	Glucose-6-phosphate dehydrogenase; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p
15137	S000001207	ORF	Verified	YHR164C	DNA2	8	429179	424611	C	Essential tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; required for Okazaki fragment processing; involved in DNA repair pathways; potential Cdc28p substrate
15139	S000028783	ORF	Dubious	YHR165W-A	n.a.	8	436648	436959	W	Questionable ORF from MIPS
15141	S000001208	ORF	Verified	YHR165C	PRP8	8	436949	429708	C	Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing
15143	S000001209	ORF	Verified	YHR166C	CDC23	8	439051	437171	C	Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition
15145	S000001210	ORF	Verified	YHR167W	THP2	8	439343	440128	W	Subunit of the THO complex, which functions to connect transcription elongation with mitotic recombination, and of the TREX complex, which is recruited to activated genes and couples transcription to mRNA export
15147	S000001211	ORF	Verified	YHR168W	MTG2	8	440378	441877	W	Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly
15149	S000001212	ORF	Verified	YHR169W	DBP8	8	442181	443476	W	Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit
15151	S000001213	ORF	Verified	YHR170W	NMD3	8	443828	445384	W	Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex
15153	S000001214	ORF	Verified	YHR171W	ATG7	8	445712	447604	W	Autophagy-related protein that is a member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p, a required step in the formation of autophagosomes
15155	S000001215	ORF	Verified	YHR172W	SPC97	8	448334	450805	W	Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque
15157	S000001216	ORF	Dubious	YHR173C	n.a.	8	451152	450814	C	Hypothetical protein
15159	S000001217	ORF	Verified	YHR174W	ENO2	8	451326	452639	W	Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose
15161	S000001218	ORF	Verified	YHR175W	CTR2	8	452871	453440	W	Putative low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation
15163	S000028553	ORF	Uncharacterized	YHR175W-A	n.a.	8	453557	453706	W	Identified by fungal homology and RT-PCR
15165	S000001219	ORF	Verified	YHR176W	FMO1	8	454228	455526	W	Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins
15167	S000001220	ORF	Uncharacterized	YHR177W	n.a.	8	456590	457951	W	ORF, Uncharacterized
15169	S000001221	ORF	Verified	YHR178W	STB5	8	459298	461529	W	Activator of multidrug resistance genes, forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a PDRE (pleotropic drug resistance element) in vitro; binds Sin3p in a two-hybrid assay
15171	S000001222	ORF	Verified	YHR179W	OYE2	8	462501	463703	W	Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism
15174	S000001223	ORF	Dubious	YHR180W	n.a.	8	465177	465668	W	Hypothetical protein
15177	S000028555	ORF	Dubious	YHR180W-A	n.a.	8	466931	467113	W	Identified by fungal homology and RT-PCR
15180	S000006751	tRNA	n.a.	tT(UGU)H	n.a.	8	466989	467060	W	tRNA-Thr
15182	S000028554	ORF	Dubious	YHR180C-B	n.a.	8	467061	466957	C	Identified by fungal homology and RT-PCR
15184	S000001224	ORF	Uncharacterized	YHR181W	n.a.	8	467227	467913	W	Component of Sed5p vesicles
15186	S000001225	ORF	Uncharacterized	YHR182W	n.a.	8	468218	470575	W	Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and cytoplasm
15188	S000001226	ORF	Verified	YHR183W	GND1	8	470959	472428	W	6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress
15190	S000028784	ORF	Dubious	YHR182C-A	n.a.	8	471411	470938	C	Hypothetical protein
15192	S000001227	ORF	Verified	YHR184W	SSP1	8	472743	474458	W	Protein involved in the control of meiotic nuclear division and coordination of meiosis with spore formation; transcription is induced midway through meiosis
15194	S000001228	ORF	Verified	YHR185C	PFS1	8	475339	474626	C	Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies of a cell during meiosis II; not required for meiotic recombination or meiotic chromosome segregation
15196	S000006768	tRNA	n.a.	tV(CAC)H	n.a.	8	475777	475705	C	tRNA-Val
15198	S000001229	ORF	Verified	YHR186C	KOG1	8	480671	475998	C	Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors
15200	S000001230	ORF	Verified	YHR187W	IKI1	8	480989	481918	W	Subunit of the Elp4p-Iki1p-Elp6p-subcomplex of RNA polymerase II elongator complex, which is a histone acetyltransferase; iki1 mutations confer resistance to the K. lactis toxin zymocin
15202	S000001231	ORF	Verified	YHR188C	GPI16	8	483836	482004	C	Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog
15204	S000001232	ORF	Verified	YHR189W	PTH1	8	484027	484599	W	One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for cell growth and for mitochondrial respiration
15206	S000001233	ORF	Verified	YHR190W	ERG9	8	484844	486178	W	Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway
15208	S000001234	ORF	Verified	YHR191C	CTF8	8	486630	486229	C	Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion
15210	S000001235	ORF	Uncharacterized	YHR192W	n.a.	8	486825	487661	W	Hypothetical protein
15212	S000001236	ORF	Verified	YHR193C	EGD2	8	488235	487711	C	Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes
15214	S000001237	ORF	Verified	YHR194W	MDM31	8	488656	490395	W	Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34
15216	S000028785	ORF	Dubious	YHR193C-A	n.a.	8	489026	488652	C	Questionable ORF from MIPS
15218	S000001238	ORF	Verified	YHR195W	NVJ1	8	490746	491711	W	Nuclear envelope protein that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)
15220	S000001239	ORF	Verified	YHR196W	UTP9	8	491930	493657	W	Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA
15222	S000001240	ORF	Verified	YHR197W	RIX1	8	493895	496186	W	Essential protein involved in the processing of the ITS2 region of the rRNA locus; required for the maturation and nuclear export of the 60S ribosomal subunit
15224	S000001241	ORF	Uncharacterized	YHR198C	n.a.	8	497279	496314	C	The authentic, non-tagged protein was localized to the mitochondria
15226	S000001242	ORF	Uncharacterized	YHR199C	n.a.	8	498421	497489	C	The authentic, non-tagged protein was localized to the mitochondria
15228	S000029704	ORF	Uncharacterized	YHR199C-A	n.a.	8	498858	498570	C	ORF, Uncharacterized
15231	S000036812	intron	n.a.	n.a.	n.a.	8	498785	498719	C	n.a.
15232	S000001243	ORF	Verified	YHR200W	RPN10	8	499078	499884	W	Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein
15234	S000001244	ORF	Verified	YHR201C	PPX1	8	501142	499949	C	Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix
15236	S000001245	ORF	Uncharacterized	YHR202W	n.a.	8	502387	504195	W	Hypothetical protein
15238	S000001246	ORF	Verified	YHR203C	RPS4B	8	505529	504475	C	Protein component of the small (40S) ribosomal subunit; identical to Rps4Bp and has similarity to rat S4 ribosomal protein
15241	S000037173	intron	n.a.	n.a.	n.a.	8	505515	505247	C	n.a.
15242	S000001247	ORF	Verified	YHR204W	MNL1	8	506318	508708	W	Alpha mannosidase-like protein of the endoplasmic reticulum required for degradation of glycoproteins but not for processing of N-linked oligosaccharides
15244	S000001248	ORF	Verified	YHR205W	SCH9	8	509362	511836	W	Protein kinase that regulates signal transduction activity and G1 progression, controls cAPK activity, required for nitrogen activation of the FGM pathway, involved in life span regulation, homologous to mammalian Akt/PKB
15246	S000001249	ORF	Verified	YHR206W	SKN7	8	512731	514599	W	Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation
15248	S000001250	ORF	Verified	YHR207C	SET5	8	516484	514904	C	Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus
15250	S000001251	ORF	Verified	YHR208W	BAT1	8	517531	518712	W	Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase
15252	S000001252	ORF	Uncharacterized	YHR209W	n.a.	8	519436	520311	W	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
15254	S000001253	ORF	Uncharacterized	YHR210C	n.a.	8	521736	520711	C	Hypothetical protein
15256	S000001254	ORF	Verified	YHR211W	FLO5	8	525391	528618	W	Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p
15259	S000001255	ORF	Dubious	YHR212C	n.a.	8	538093	537758	C	Hypothetical protein
15261	S000028650	ORF	Uncharacterized	YHR212W-A	n.a.	8	538741	538944	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15263	S000001256	ORF	Uncharacterized	YHR213W	n.a.	8	539150	539746	W	Hypothetical protein
15265	S000028651	ORF	Uncharacterized	YHR213W-A	n.a.	8	540548	540781	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15267	S000028652	ORF	Uncharacterized	YHR213W-B	n.a.	8	540799	541098	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15269	S000001257	ORF	Uncharacterized	YHR214W	n.a.	8	541650	542261	W	putative membrane protein
15271	S000003535	ORF	Dubious	YHR214W-A	n.a.	8	543007	543492	W	Hypothetical protein
15282	S000028653	ORF	Uncharacterized	YHR214C-D	n.a.	8	550940	550647	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15284	S000028654	ORF	Uncharacterized	YHR214C-E	n.a.	8	551498	551199	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15286	S000001258	ORF	Verified	YHR215W	PHO12	8	552098	553501	W	One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; nearly identical to Pho11p; upregulated by phosphate starvation
15288	S000001259	ORF	Verified	YHR216W	IMD2	8	554395	555966	W	Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation
15299	S000001260	ORF	Dubious	YHR217C	n.a.	8	557041	556580	C	Hypothetical protein
15301	S000001261	ORF	Uncharacterized	YHR218W	n.a.	8	558013	559923	W	Hypothetical protein
15304	S000034724	intron	n.a.	n.a.	n.a.	8	558615	558713	W	n.a.
15305	S000028786	ORF	Dubious	YHR218W-A	n.a.	8	559931	560248	W	Hypothetical protein
15307	S000001262	ORF	Uncharacterized	YHR219W	n.a.	8	560172	562046	W	Hypothetical protein
15309	S000028655	ORF	Dubious	YHR219C-A	n.a.	8	561680	561198	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15314	S000028658	ORF	Dubious	YIL177W-A	n.a.	9	846	1328	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15316	S000001439	ORF	Uncharacterized	YIL177C	n.a.	9	6147	483	C	Hypothetical protein
15319	S000034518	intron	n.a.	n.a.	n.a.	9	4986	4599	C	n.a.
15328	S000001438	ORF	Uncharacterized	YIL176C	n.a.	9	9155	8793	C	Hypothetical protein
15334	S000001435	ORF	Verified	YIL173W	VTH1	9	11492	16141	W	Putative membrane glycoprotein with strong similarity to Vth2p and Pep1p/Vps10p, may be involved in vacuolar protein sorting
15336	S000028798	ORF	Dubious	YIL171W-A	n.a.	9	18260	18712	W	Questionable ORF from MIPS
15338	S000001434	ORF	Uncharacterized	YIL172C	n.a.	9	18553	16784	C	Hypothetical protein
15344	S000001431	ORF	Uncharacterized	YIL169C	n.a.	9	26106	23119	C	Hypothetical protein
15350	S000001428	ORF	Uncharacterized	YIL166C	n.a.	9	32566	30938	C	Hypothetical protein, member of the Dal5p subfamily of the major facilitator family
15352	S000001427	ORF	Uncharacterized	YIL165C	n.a.	9	34077	33718	C	Hypothetical protein
15354	S000001426	ORF	Verified	YIL164C	NIT1	9	34686	34087	C	Nitrilase, member of the widely found nitrilase branch (EC:3.5.5.1) of the nitrilase superfamily
15356	S000001425	ORF	Dubious	YIL163C	n.a.	9	37252	36899	C	Hypothetical protein
15358	S000001424	ORF	Verified	YIL162W	SUC2	9	37385	38983	W	Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively
15360	S000001423	ORF	Uncharacterized	YIL161W	n.a.	9	39433	40140	W	Hypothetical protein
15362	S000001422	ORF	Verified	YIL160C	POT1	9	41444	40191	C	3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids
15364	S000001421	ORF	Verified	YIL159W	BNR1	9	41825	45952	W	Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1
15366	S000001420	ORF	Uncharacterized	YIL158W	n.a.	9	46201	46815	W	Hypothetical protein
15368	S000028797	ORF	Dubious	YIL156W-A	n.a.	9	47292	47693	W	Questionable ORF from MIPS
15370	S000001419	ORF	Uncharacterized	YIL157C	n.a.	9	47542	46949	C	The authentic, non-tagged protein was localized to the mitochondria
15372	S000028511	ORF	Dubious	YIL156W-B	n.a.	9	47690	47973	W	Identified based on homology to <i>Ashbya gossypii</i>
15375	S000030267	intron	n.a.	n.a.	n.a.	9	47699	47760	W	n.a.
15376	S000001418	ORF	Verified	YIL156W	UBP7	9	48091	51306	W	Ubiquitin-specific protease that cleaves ubiquitin-protein fusions
15378	S000001417	ORF	Verified	YIL155C	GUT2	9	53708	51759	C	Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner
15380	S000001416	ORF	Verified	YIL154C	IMP2'	9	55021	53981	C	Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat
15382	S000001415	ORF	Verified	YIL153W	RRD1	9	55198	56379	W	Activator of the phosphotyrosyl phosphatase activity of PP2A; regulates G1 phase progression, the G2/M phase transition, microtubule dynamics, the osmoresponse, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex
15384	S000001414	ORF	Uncharacterized	YIL152W	n.a.	9	56545	57252	W	Hypothetical protein
15386	S000001413	ORF	Uncharacterized	YIL151C	n.a.	9	60694	57338	C	Hypothetical protein
15388	S000001412	ORF	Verified	YIL150C	MCM10	9	62728	61013	C	Essential, chromatin-associated protein involved in the initiation of DNA replication; required for the association of the MCM2-7 complex with replication origins
15390	S000001411	ORF	Verified	YIL149C	MLP2	9	68067	63028	C	Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length
15392	S000001410	ORF	Verified	YIL148W	RPL40A	9	68708	69528	W	Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes
15395	S000031653	intron	n.a.	n.a.	n.a.	9	68716	69149	W	n.a.
15396	S000001409	ORF	Verified	YIL147C	SLN1	9	73453	69791	C	Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators
15398	S000001408	ORF	Verified	YIL146C	ECM37	9	75773	74184	C	Non-essential protein of unknown function
15400	S000001407	ORF	Verified	YIL145C	PAN6	9	77283	76354	C	Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC
15402	S000001406	ORF	Verified	YIL144W	TID3	9	78074	80149	W	Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering
15404	S000001405	ORF	Verified	YIL143C	SSL2	9	83041	80510	C	Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3
15406	S000001404	ORF	Verified	YIL142W	CCT2	9	83302	84885	W	Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo
15408	S000028796	ORF	Dubious	YIL142C-A	n.a.	9	83540	83208	C	Hypothetical protein
15410	S000001403	ORF	Dubious	YIL141W	n.a.	9	85053	85442	W	Hypothetical protein
15412	S000001402	ORF	Verified	YIL140W	AXL2	9	85366	87837	W	Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate
15414	S000001401	ORF	Verified	YIL139C	REV7	9	88716	87979	C	Subunit of DNA polymerase zeta, which is involved in DNA repair; required for mutagenesis induced by DNA damage
15416	S000001400	ORF	Verified	YIL138C	TPM2	9	89715	89230	C	Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p
15418	S000001399	ORF	Uncharacterized	YIL137C	n.a.	9	92788	89948	C	Putative metalloprotease
15420	S000001398	ORF	Verified	YIL136W	OM45	9	93619	94800	W	Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane
15422	S000001397	ORF	Verified	YIL135C	VHS2	9	96375	95065	C	Cytoplasmic protein of unknown function; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; similar to Mlf3p
15424	S000028556	ORF	Uncharacterized	YIL134C-A	n.a.	9	96725	96522	C	Identified by fungal homology and RT-PCR
15426	S000006459	snoRNA	n.a.	snR68	SNR68	9	97111	97246	W	guides 2'-O-methylation on large subunit rRNA at A2637; small nucleolar RNA snR68
15428	S000001396	ORF	Verified	YIL134W	FLX1	9	97395	98330	W	Protein required for transport of flavin adenine dinucleotide (FAD) from mitochondria, where it is synthesized from riboflavin, to the cytosol
15430	S000001395	ORF	Verified	YIL133C	RPL16A	9	99416	98527	C	N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p
15433	S000033254	intron	n.a.	n.a.	n.a.	9	99385	99096	C	n.a.
15434	S000001394	ORF	Verified	YIL132C	CSM2	9	100501	99860	C	Protein required for accurate chromosome segregation during meiosis
15436	S000001393	ORF	Verified	YIL131C	FKH1	9	102235	100781	C	Transcription factor of the forkhead family that regulates the cell cycle and pseudohyphal growth; also involved in chromatin silencing at HML and HMR
15438	S000001392	ORF	Uncharacterized	YIL130W	n.a.	9	102782	105676	W	Proposed transcriptional activator, member of the Gal4p family of zinc cluster proteins
15440	S000001391	ORF	Verified	YIL129C	TAO3	9	113237	106107	C	Protein involved in cell morphogenesis and proliferation, associated with protein kinase Cbk1p; mutants activate OCH1 transcription
15442	S000001390	ORF	Verified	YIL128W	MET18	9	113806	116904	W	DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; possible role in assembly of a multiprotein complex(es) required for NER and RNAP II transcription
15444	S000001389	ORF	Uncharacterized	YIL127C	n.a.	9	117644	117024	C	Hypothetical protein
15446	S000001388	ORF	Verified	YIL126W	STH1	9	117992	122071	W	ATPase component of the ATP-dependent RSC chromatin remodeling complex required for kinetochore function in chromosome segregation; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p
15448	S000001387	ORF	Verified	YIL125W	KGD1	9	122689	125733	W	Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA
15450	S000001386	ORF	Verified	YIL124W	AYR1	9	126204	127097	W	NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles and ER; involved in phosphatidic acid biosynthesis and required for spore germination; capable of metabolizing mammalian steroid hormones
15452	S000001385	ORF	Verified	YIL123W	SIM1	9	128151	129578	W	Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated
15454	S000001384	ORF	Verified	YIL122W	POG1	9	130607	131662	W	Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated
15456	S000001383	ORF	Verified	YIL121W	QDR2	9	132241	133869	W	Multidrug transporter required for resistance to quinidine, barban, cisplatin, and bleomycin; member of the major facilitator superfamily of transporters conferring multiple drug resistance (MFS-MDR)
15458	S000001382	ORF	Verified	YIL120W	QDR1	9	134414	136105	W	Multidrug transporter required for resistance to quinidine, ketoconazole, fluconazole, and barban; member of the major facilitator superfamily of transporters conferring multiple drug resistance (MFS-MDR)
15460	S000001381	ORF	Verified	YIL119C	RPI1	9	137874	136651	C	Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation
15462	S000001380	ORF	Verified	YIL118W	RHO3	9	139749	140444	W	Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p
15464	S000001379	ORF	Verified	YIL117C	PRM5	9	141566	140610	C	Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling
15466	S000001378	ORF	Verified	YIL116W	HIS5	9	142925	144082	W	Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
15468	S000028795	ORF	Dubious	YIL115W-A	n.a.	9	144265	144636	W	Questionable ORF from MIPS
15470	S000001377	ORF	Verified	YIL115C	NUP159	9	148706	144324	C	Subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export
15472	S000001376	ORF	Verified	YIL114C	POR2	9	149985	149140	C	Putative mitochondrial porin (voltage-dependent anion channel), related to Por1p but not required for mitochondrial membrane permeability or mitochondrial osmotic stability
15474	S000001375	ORF	Verified	YIL113W	SDP1	9	150556	151185	W	Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock
15476	S000001374	ORF	Uncharacterized	YIL112W	HOS4	9	151592	154843	W	Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate
15478	S000001373	ORF	Verified	YIL111W	COX5B	9	155219	155762	W	Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth
15481	S000033708	intron	n.a.	n.a.	n.a.	9	155220	155307	W	n.a.
15482	S000001372	ORF	Uncharacterized	YIL110W	n.a.	9	156042	157175	W	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
15484	S000001371	ORF	Verified	YIL109C	SEC24	9	160162	157382	C	Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p
15486	S000001370	ORF	Uncharacterized	YIL108W	n.a.	9	160884	162974	W	Putative metalloprotease
15488	S000001369	ORF	Verified	YIL107C	PFK26	9	165758	163275	C	6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, has negligible fructose-2,6-bisphosphatase activity, transcriptional regulation involves protein kinase A
15490	S000001368	ORF	Verified	YIL106W	MOB1	9	166412	167441	W	Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex
15493	S000031987	intron	n.a.	n.a.	n.a.	9	166432	166516	W	n.a.
15494	S000028657	ORF	Dubious	YIL105W-A	n.a.	9	167661	167801	W	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15496	S000001367	ORF	Verified	YIL105C	SLM1	9	169638	167578	C	Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; phosphorylated by the Tor2p-containing complex TORC2
15498	S000001366	ORF	Verified	YIL104C	SHQ1	9	171502	169979	C	Essential nuclear protein, required for accumulation of box H/ACA snoRNAs and for rRNA processing; interacts with Naf1p
15500	S000001365	ORF	Verified	YIL103W	DPH1	9	171748	173025	W	Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p
15502	S000001364	ORF	Uncharacterized	YIL102C	n.a.	9	174884	174579	C	Hypothetical protein
15504	S000006741	tRNA	n.a.	tT(AGU)I1	n.a.	9	175028	175100	W	tRNA-Thr
15506	S000001363	ORF	Verified	YIL101C	XBP1	9	177247	175304	C	Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate
15508	S000001362	ORF	Dubious	YIL100W	n.a.	9	177370	177723	W	Hypothetical protein
15510	S000028794	ORF	Dubious	YIL100C-A	n.a.	9	177678	177340	C	Questionable ORF from MIPS
15512	S000001361	ORF	Verified	YIL099W	SGA1	9	178001	179650	W	Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation
15514	S000001360	ORF	Verified	YIL098C	FMC1	9	180236	179769	C	Mitochondrial matrix protein, required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase
15516	S000001359	ORF	Verified	YIL097W	FYV10	9	180424	181974	W	Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains CTLH domain
15518	S000001358	ORF	Uncharacterized	YIL096C	n.a.	9	183124	182114	C	Hypothetical protein
15520	S000006605	tRNA	n.a.	tI(AAU)I1	n.a.	9	183510	183437	C	tRNA-Ile
15522	S000001357	ORF	Verified	YIL095W	PRK1	9	183934	186366	W	Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex
15524	S000001356	ORF	Verified	YIL094C	LYS12	9	187629	186514	C	Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate
15526	S000001355	ORF	Verified	YIL093C	RSM25	9	188781	187987	C	Mitochondrial ribosomal protein of the small subunit
15528	S000001354	ORF	Uncharacterized	YIL092W	n.a.	9	189063	190964	W	Hypothetical protein
15530	S000001353	ORF	Uncharacterized	YIL091C	n.a.	9	193192	191027	C	Protein required for cell viability
15532	S000001352	ORF	Verified	YIL090W	ICE2	9	193592	195067	W	Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells
15534	S000001351	ORF	Uncharacterized	YIL089W	n.a.	9	195596	196213	W	Hypothetical protein
15538	S000006547	tRNA	n.a.	tE(CUC)I	n.a.	9	197589	197660	W	tRNA-Glu
15540	S000001350	ORF	Verified	YIL088C	AVT7	9	199400	197928	C	Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters
15542	S000001349	ORF	Uncharacterized	YIL087C	n.a.	9	200116	199643	C	Hypothetical protein
15544	S000001348	ORF	Dubious	YIL086C	n.a.	9	200458	200150	C	Hypothetical protein
15546	S000001347	ORF	Verified	YIL085C	KTR7	9	202040	200487	C	Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family
15548	S000001346	ORF	Verified	YIL084C	SDS3	9	203256	202273	C	Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes
15550	S000001345	ORF	Uncharacterized	YIL083C	n.a.	9	204650	203553	C	Homolog to human PPCS
15562	S000001344	ORF	Dubious	YIL082W	n.a.	9	205632	206504	W	Hypothetical protein
15565	S000006606	tRNA	n.a.	tI(AAU)I2	n.a.	9	210662	210735	W	tRNA-Ile
15567	S000001341	ORF	Verified	YIL079C	AIR1	9	212002	210920	C	RING finger protein that interacts with the arginine methyltransferase Hmt1p to regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air2p
15569	S000001340	ORF	Verified	YIL078W	THS1	9	212496	214700	W	Threonyl-tRNA synthetase, essential cytoplasmic protein
15572	S000001339	ORF	Uncharacterized	YIL077C	n.a.	9	215950	214988	C	Hypothetical protein
15574	S000001338	ORF	Verified	YIL076W	SEC28	9	216466	217545	W	Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth
15576	S000001337	ORF	Verified	YIL075C	RPN2	9	220697	217860	C	Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p
15578	S000001336	ORF	Verified	YIL074C	SER33	9	222487	221078	C	3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p
15580	S000001335	ORF	Verified	YIL073C	SPO22	9	225951	222934	C	Meiosis-specific protein with similarity to phospholipase A2, involved in completion of nuclear divisions during meiosis; induced early in meiosis
15583	S000030518	intron	n.a.	n.a.	n.a.	9	225896	225807	C	n.a.
15584	S000001334	ORF	Verified	YIL072W	HOP1	9	226599	228416	W	Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation
15586	S000028793	ORF	Dubious	YIL071W-A	n.a.	9	228547	229023	W	Questionable ORF from MIPS
15588	S000001333	ORF	Verified	YIL071C	PCI8	9	229991	228657	C	Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain
15590	S000001332	ORF	Verified	YIL070C	MAM33	9	231069	230269	C	Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation; related to the human complement receptor gC1q-R
15592	S000001331	ORF	Verified	YIL069C	RPS24B	9	232366	231550	C	Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein
15595	S000036652	intron	n.a.	n.a.	n.a.	9	232363	231955	C	n.a.
15596	S000028792	ORF	Dubious	YIL068W-A	n.a.	9	233010	233393	W	Questionable ORF from MIPS
15598	S000001330	ORF	Verified	YIL068C	SEC6	9	235471	233054	C	Essential 88kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis
15600	S000028791	ORF	Dubious	YIL066W-A	n.a.	9	237363	237806	W	Questionable ORF from MIPS
15602	S000001329	ORF	Uncharacterized	YIL067C	n.a.	9	237757	235721	C	Hypothetical protein
15604	S000001328	ORF	Verified	YIL066C	RNR3	9	240705	238096	C	Ribonucleotide-diphosphate reductase (RNR), large subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
15606	S000001327	ORF	Verified	YIL065C	FIS1	9	241772	241305	C	Mitochondrial outer membrane protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division
15608	S000001326	ORF	Uncharacterized	YIL064W	n.a.	9	241940	242713	W	Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family
15610	S000001325	ORF	Verified	YIL063C	YRB2	9	243741	242758	C	Ran-GTPase-binding protein involved in nuclear export; nuclear protein, interacts with Gsp1p and Crm1p
15612	S000001324	ORF	Verified	YIL062C	ARC15	9	244459	243995	C	Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches
15614	S000001323	ORF	Verified	YIL061C	SNP1	9	245556	244654	C	U1snRNP 70K protein homolog
15616	S000001322	ORF	Uncharacterized	YIL060W	n.a.	9	246389	246823	W	Hypothetical protein
15619	S000001320	ORF	Dubious	YIL058W	n.a.	9	246911	247195	W	Hypothetical protein
15621	S000001321	ORF	Dubious	YIL059C	n.a.	9	246912	246547	C	Hypothetical protein
15623	S000001319	ORF	Uncharacterized	YIL057C	n.a.	9	248393	247899	C	Hypothetical protein
15625	S000006735	tRNA	n.a.	tS(UGA)I	SUP17	9	248847	248928	W	tRNA-Ser
15627	S000001318	ORF	Uncharacterized	YIL056W	n.a.	9	249989	251911	W	Hypothetical protein
15629	S000001317	ORF	Uncharacterized	YIL055C	n.a.	9	253923	252040	C	Hypothetical protein
15631	S000001316	ORF	Dubious	YIL054W	n.a.	9	254541	254858	W	Hypothetical protein
15633	S000001315	ORF	Verified	YIL053W	RHR2	9	255050	255865	W	Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress
15635	S000001314	ORF	Verified	YIL052C	RPL34B	9	257061	256224	C	Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein
15638	S000030948	intron	n.a.	n.a.	n.a.	9	257024	256553	C	n.a.
15639	S000001313	ORF	Verified	YIL051C	MMF1	9	258279	257842	C	Mitochondrial protein involved in maintenance of the mitochondrial genome
15641	S000001312	ORF	Verified	YIL050W	PCL7	9	258912	259769	W	Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated
15643	S000001311	ORF	Verified	YIL049W	DFG10	9	260157	260918	W	Protein of unknown function, involved in filamentous growth
15645	S000001310	ORF	Verified	YIL048W	NEO1	9	261436	264891	W	Protein involved in the retrograde transport from the Golgi complex to the ER and the endosomal membrane traffic; putative aminophospholipid translocase; member of the highly conserved Drs2 family of P-type ATPases
15647	S000028790	ORF	Dubious	YIL047C-A	n.a.	9	265466	265098	C	Questionable ORF from MIPS
15649	S000001309	ORF	Verified	YIL047C	SYG1	9	267822	265114	C	Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency
15651	S000028836	ORF	Uncharacterized	YIL046W-A	n.a.	9	268308	268472	W	Identified by expression profiling and mass spectrometry
15653	S000001308	ORF	Verified	YIL046W	MET30	9	268650	270572	W	F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus
15655	S000001307	ORF	Verified	YIL045W	PIG2	9	271160	272776	W	Protein that interacts with glycogen synthase, Gsy2p
15657	S000001306	ORF	Verified	YIL044C	AGE2	9	273845	272949	C	ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif
15659	S000001305	ORF	Verified	YIL043C	CBR1	9	275039	274071	C	cytochrome b reductase
15661	S000001304	ORF	Uncharacterized	YIL042C	n.a.	9	276291	275107	C	Hypothetical protein
15663	S000001303	ORF	Uncharacterized	YIL041W	n.a.	9	276524	277504	W	Golgi-vesicle protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm
15665	S000001302	ORF	Verified	YIL040W	APQ12	9	277722	278138	W	Protein involved in nucleocytoplasmic transport of mRNA
15667	S000001301	ORF	Uncharacterized	YIL039W	n.a.	9	278425	279846	W	Hypothetical protein
15669	S000001300	ORF	Verified	YIL038C	NOT3	9	282651	280141	C	Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation
15671	S000001299	ORF	Verified	YIL037C	PRM2	9	284998	283028	C	Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p
15673	S000001298	ORF	Verified	YIL036W	CST6	9	285665	287428	W	Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources
15675	S000001297	ORF	Verified	YIL035C	CKA1	9	288907	287789	C	Alpha subunit of protein kinase casein kinase-2 (CK2), a spontaneously active, ubiquitous, pleiotropic enzyme that phosphorylates seryl/threonyl residues specified by multiple negatively charged side chains (consensus S/T-x-x-E/D/S(P)/T(P)
15677	S000001296	ORF	Verified	YIL034C	CAP2	9	290088	289225	C	Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches
15679	S000001295	ORF	Verified	YIL033C	BCY1	9	291668	290418	C	Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation
15681	S000001294	ORF	Dubious	YIL032C	n.a.	9	292316	291960	C	Hypothetical protein
15683	S000001293	ORF	Verified	YIL031W	ULP2	9	292632	295736	W	Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate
15685	S000028789	ORF	Dubious	YIL030W-A	n.a.	9	295564	295902	W	Questionable ORF from MIPS
15687	S000028788	ORF	Dubious	YIL029W-A	n.a.	9	299734	300105	W	Questionable ORF from MIPS
15689	S000001292	ORF	Verified	YIL030C	SSM4	9	300008	296049	C	Ubiquitin-protein ligase of the ER/nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation
15691	S000006624	tRNA	n.a.	tK(CUU)I	n.a.	9	300298	300227	C	tRNA-Lys
15694	S000001291	ORF	Uncharacterized	YIL029C	n.a.	9	301255	300827	C	Hypothetical protein
15696	S000001290	ORF	Dubious	YIL028W	n.a.	9	302098	302496	W	Hypothetical protein
15698	S000001289	ORF	Verified	YIL027C	KRE27	9	304102	303677	C	Protein of unknown function; null mutant shows K1 killer toxin resistance
15700	S000001288	ORF	Verified	YIL026C	IRR1	9	307927	304475	C	Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability
15702	S000001287	ORF	Dubious	YIL025C	n.a.	9	308573	308199	C	Hypothetical protein
15704	S000001286	ORF	Uncharacterized	YIL024C	n.a.	9	309169	308600	C	Hypothetical protein
15706	S000001285	ORF	Uncharacterized	YIL023C	n.a.	9	310424	309384	C	Hypothetical protein
15708	S000001284	ORF	Verified	YIL022W	TIM44	9	311163	312458	W	Peripheral mitochondrial membrane protein involved in mitochondrial protein import, tethers essential chaperone Ssc1p to the translocon channel at the matrix side of the inner membrane
15710	S000001283	ORF	Verified	YIL021W	RPB3	9	312903	313859	W	RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit
15712	S000028656	ORF	Dubious	YIL021C-A	n.a.	9	313466	313197	C	Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching
15714	S000028787	ORF	Dubious	YIL020C-A	n.a.	9	314049	313711	C	Questionable ORF from MIPS
15716	S000001282	ORF	Verified	YIL020C	HIS6	9	314818	314033	C	Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts
15718	S000001281	ORF	Verified	YIL019W	FAF1	9	315091	316131	W	Protein required for pre-rRNA processing and 40S ribosomal subunit assembly
15720	S000001280	ORF	Verified	YIL018W	RPL2B	9	316766	317930	W	Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures
15723	S000036026	intron	n.a.	n.a.	n.a.	9	316770	317169	W	n.a.
15724	S000001279	ORF	Verified	YIL017C	VID28	9	320963	318198	C	Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm
15726	S000001278	ORF	Verified	YIL016W	SNL1	9	321452	321931	W	Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein
15728	S000001277	ORF	Verified	YIL015W	BAR1	9	322340	324103	W	Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest
15730	S000006534	tRNA	n.a.	tD(GUC)I1	n.a.	9	324372	324301	C	tRNA-Asp
15734	S000003536	ORF	Uncharacterized	YIL014C-A	n.a.	9	325524	325210	C	Hypothetical protein
15736	S000006742	tRNA	n.a.	tT(AGU)I2	n.a.	9	325746	325818	W	tRNA-Thr
15738	S000001276	ORF	Verified	YIL014W	MNT3	9	326101	327993	W	Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation
15740	S000001275	ORF	Verified	YIL013C	PDR11	9	332440	328205	C	Membrane protein of the ATP-binding cassette (ABC) transporter superfamily, involved in multiple drug resistance, mediates sterol uptake when sterol biosynthesis is compromised, regulated by Pdr1p, required for anaerobic growth
15742	S000001274	ORF	Dubious	YIL012W	n.a.	9	333009	333401	W	Hypothetical protein
15744	S000001273	ORF	Verified	YIL011W	TIR3	9	333724	334533	W	Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth
15746	S000001272	ORF	Verified	YIL010W	DOT5	9	334879	335526	W	Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase during post-diauxic growth
15748	S000006432	ORF	Verified	YIL009C-A	EST3	9	336209	335663	C	Component of the telomerase holoenzyme, involved in telomere replication
15752	S000006535	tRNA	n.a.	tD(GUC)I2	n.a.	9	336417	336346	C	tRNA-Asp
15755	S000001271	ORF	Verified	YIL009W	FAA3	9	339341	341425	W	Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery
15757	S000001270	ORF	Verified	YIL008W	URM1	9	342533	342832	W	Ubiquitin-like protein with only weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature
15759	S000001269	ORF	Verified	YIL007C	NAS2	9	343653	342991	C	Protein with similarity to the p27 subunit of mammalian proteasome modulator; not essential; interacts with Rpn4p
15761	S000001268	ORF	Verified	YIL006W	n.a.	9	344059	345180	W	Pvruvate transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; has putative mouse and human orthologs
15763	S000001267	ORF	Verified	YIL005W	EPS1	9	345689	347794	W	Pdi1p (protein disulfide isomerase)-related protein involved in endoplasmic reticulum retention of resident ER proteins
15765	S000001266	ORF	Verified	YIL004C	BET1	9	348502	347943	C	Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins
15768	S000037581	intron	n.a.	n.a.	n.a.	9	348491	348361	C	n.a.
15769	S000001265	ORF	Verified	YIL003W	CFD1	9	349119	350000	W	Highly conserved, putative P-loop ATPase localized in the cytoplasm; has a potential role in assembly of iron-sulfur clusters in proteins
15771	S000028835	ORF	Uncharacterized	YIL002W-A	n.a.	9	350298	350507	W	Identified by expression profiling and mass spectrometry
15773	S000001264	ORF	Verified	YIL002C	INP51	9	353428	350588	C	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth
15775	S000001263	ORF	Uncharacterized	YIL001W	n.a.	9	353937	355478	W	Hypothetical protein
15781	S000001440	ORF	Verified	YIR001C	SGN1	9	356892	356140	C	Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation
15783	S000001441	ORF	Verified	YIR002C	MPH1	9	360393	357412	C	Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, mutations confer a mutator phenotype
15785	S000001442	ORF	Uncharacterized	YIR003W	n.a.	9	360882	362921	W	Hypothetical protein
15787	S000001443	ORF	Verified	YIR004W	DJP1	9	363218	364516	W	Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in peroxisome assembly, homologous to E. coli DnaJ
15789	S000001444	ORF	Verified	YIR005W	IST3	9	364886	365332	W	Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing
15791	S000001445	ORF	Verified	YIR006C	PAN1	9	369905	365463	C	Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease
15793	S000006556	tRNA	n.a.	tE(UUC)I	n.a.	9	370414	370485	W	tRNA-Glu
15795	S000001446	ORF	Uncharacterized	YIR007W	n.a.	9	370701	372995	W	Hypothetical protein
15797	S000001447	ORF	Verified	YIR008C	PRI1	9	374303	373074	C	Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair
15799	S000001448	ORF	Verified	YIR009W	MSL1	9	374522	374857	W	U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro; does not contain the conserved C-terminal RNA binding domain found in other family members
15801	S000001449	ORF	Verified	YIR010W	DSN1	9	375428	377158	W	Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation
15803	S000001450	ORF	Verified	YIR011C	STS1	9	378243	377284	C	Protein that interacts with the karyopherin Srp1p; may have a role with Srp1p in ubiquitin-mediated protein degradation
15805	S000001451	ORF	Verified	YIR012W	SQT1	9	378483	379778	W	Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay
15807	S000001452	ORF	Verified	YIR013C	GAT4	9	380381	380016	C	Protein containing GATA family zinc finger motifs
15809	S000001453	ORF	Uncharacterized	YIR014W	n.a.	9	381083	381811	W	Hypothetical protein
15811	S000001454	ORF	Verified	YIR015W	RPR2	9	381945	382379	W	Subunit of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; not shared between Rnase MRP and Rnase P, in contrast to all other Rnase P protein subunits
15813	S000001455	ORF	Uncharacterized	YIR016W	n.a.	9	382625	383422	W	Hypothetical protein
15815	S000028799	ORF	Dubious	YIR017W-A	n.a.	9	383563	384162	W	Questionable ORF from MIPS
15817	S000001456	ORF	Verified	YIR017C	MET28	9	384116	383553	C	Transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism
15819	S000001457	ORF	Verified	YIR018W	YAP5	9	384606	385343	W	Basic leucine zipper (bZIP) transcription factor
15821	S000028837	ORF	Uncharacterized	YIR018C-A	n.a.	9	385698	385561	C	Identified by expression profiling and mass spectrometry
15823	S000001458	ORF	Verified	YIR019C	MUC1	9	393672	389569	C	GPI-anchored cell surface glycoprotein required for diploid pseudohyphal formation and haploid invasive growth, transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)
15825	S000001459	ORF	Dubious	YIR020C	n.a.	9	394554	394252	C	Hypothetical protein
15827	S000007241	ORF	Dubious	YIR020W-A	n.a.	9	394914	395156	W	Hypothetical protein
15829	S000001460	ORF	Verified	YIR021W	MRS1	9	397291	398382	W	Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA
15831	S000028800	ORF	Dubious	YIR020C-B	n.a.	9	397946	397212	C	Questionable ORF from MIPS
15833	S000028838	ORF	Uncharacterized	YIR021W-A	n.a.	9	398511	398723	W	Identified by expression profiling and mass spectrometry
15835	S000001461	ORF	Verified	YIR022W	SEC11	9	398730	399233	W	18kDa catalytic subunit of the Signal Peptidase Complex (SPC; Spc1p, Spc2p, Spc3p, and Sec11p) which cleaves the signal sequence of proteins targeted to the endoplasmic reticulum
15837	S000001462	ORF	Verified	YIR023W	DAL81	9	399774	402686	W	Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism
15839	S000028801	ORF	Dubious	YIR023C-A	n.a.	9	402703	402380	C	Questionable ORF from MIPS
15841	S000001463	ORF	Uncharacterized	YIR024C	n.a.	9	403488	402838	C	(putative) involved in cell cycle control
15843	S000001464	ORF	Verified	YIR025W	MND2	9	403656	404762	W	Subunit of the anaphase-promoting complex (APC); needed for meiotic nuclear division
15845	S000001465	ORF	Verified	YIR026C	YVH1	9	405964	404870	C	nitrogen starvation-induced protein phosphatase
15847	S000001466	ORF	Verified	YIR027C	DAL1	9	407639	406257	C	Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression
15849	S000001467	ORF	Verified	YIR028W	DAL4	9	408465	410372	W	Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
15851	S000001468	ORF	Verified	YIR029W	DAL2	9	410804	411835	W	Allantoicase, converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
15853	S000001469	ORF	Verified	YIR030C	DCG1	9	412767	412033	C	Protein of unknown function, expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain
15855	S000028802	ORF	Dubious	YIR030W-A	n.a.	9	412896	413279	W	Hypothetical protein
15857	S000001470	ORF	Verified	YIR031C	DAL7	9	414676	413012	C	Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation
15859	S000001471	ORF	Verified	YIR032C	DAL3	9	415614	415027	C	Ureidoglycolate hydrolase, converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression sensitive to nitrogen catabolite repression
15861	S000001472	ORF	Verified	YIR033W	MGA2	9	416121	419462	W	ER membrane protein involved, with its homolog Spt23p, in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting
15863	S000001473	ORF	Verified	YIR034C	LYS1	9	420733	419612	C	Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway
15865	S000001474	ORF	Uncharacterized	YIR035C	n.a.	9	421787	421023	C	Hypothetical protein
15867	S000028803	ORF	Dubious	YIR036W-A	n.a.	9	422632	423033	W	Questionable ORF from MIPS
15869	S000001475	ORF	Uncharacterized	YIR036C	n.a.	9	422862	422071	C	Hypothetical protein
15871	S000001476	ORF	Verified	YIR037W	HYR1	9	423125	423616	W	Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor
15873	S000001477	ORF	Verified	YIR038C	GTT1	9	424510	423806	C	ER associated glutathione S-transferase capable of homodimerization; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p
15876	S000001478	ORF	Verified	YIR039C	YPS6	9	432107	430494	C	Putative GPI-anchored aspartic protease
15878	S000001479	ORF	Dubious	YIR040C	n.a.	9	433717	433385	C	Hypothetical protein
15880	S000001480	ORF	Uncharacterized	YIR041W	n.a.	9	433925	434299	W	Hypothetical protein
15882	S000001481	ORF	Uncharacterized	YIR042C	n.a.	9	435980	435270	C	Hypothetical protein