Tomás Norambuena A.

Tomás Norambuena A., Ph.D.
Postdoctoral Fellow
Ph.D. in Biological Sciences, Molecular Genetics and Microbiology
Phone: +56 (2) 354-1918
Email: tanoramb@puc.cl (tanoramb null@null puc NULL.cl)

Research project: Protein-DNA interactions. Structure-based consensus DNA binding motif prediction for sequence-based complete genome scanning of transcription factor binding sites

Selected publications:

1)    Schüller, A., Slater, A.W., Norambuena, T., Cifuentes, J.J., Almonacid, L.I. and Melo, F. (2012) Computer-based annotation of putative AraC/XylS-family transcription factors of known structure but unknown function. J Biomed Biotechnol 2012, 103132.

2)    Capriotti, E., Norambuena, T., Marti-Renom, M.A., and Melo, F. (2011) All-atom knowledge-based potential for RNA structure prediction and assessment. Bioinformatics 27, 1086-93.

3)     Norambuena, T. and Melo, F. (2010) The Protein-DNA Interface database. BMC Bioinformatics 11, 262.

4)     Kühner, S., van Noort, V., Betts, M.J., Leo-Macias, A., Batisse, C., Rode, M., Yamada, T., Maier, T., Bader, S., Beltran-Alvarez, P., Castaño-Diez, D., Chen, W.H., Devos, D., Güell, M., Norambuena, T., Racke, I., Rybin, V., Schmidt, A., Yus, E., Aebersold, R., Herrmann, R., Böttcher, B., Frangakis, A.S., Russell, R.B., Serrano, L., Bork, P., Gavin, A.C. (2009) Proteome organization in a genome-reduced bacterium. Science 326, 1235-40.

5)    Vergara, I. A., Norambuena, T., Ferrada, E., Slater, A. W. and Melo, F. (2008) StAR: a simple tool for the statistical comparison of ROC curves. BMC Bioinformatics 9, 265-269.

Selected talks and posters:

1)    Norambuena, T. and Melo, F. “Full-atom structure-based prediction of transcription factor binding sites” Presented in: ISMB 2012, Long Beach, California, USA (Poster, English) Jul 2012; ISCB Latin America 2012, Santiago, Chile (Poster, English)            Mar 2012; XXXIII Congreso Chileno de Microbiología 2011, Olmue, Chile (Oral, Spanish) Nov 2011; XXXIV Reunión Anual SBBM, Valdivia, Chile (Poster, Spanish) Sep 2011

2)    Norambuena, T. and Melo, F. “The Protein-DNA Interface database” Presented in: 1st International Conference on Bioinformatics SoIBio, Chillán, Chile (Oral, English) Sep 2010

3)    Norambuena, T. and Melo, F. “PDIdb: a novel database containing the three-dimensional interfaces of protein-DNA complexes” Presented in: ISCB Latin America 2010, Montevideo, Uruguay (Poster, English) Mar 2010